| Compound ID |
Compound Name |
Compound Formula |
|
CP0411141
|
(11S)-N-[(4-cyanophenyl)methyl]-5-ethyl-6,11-dioxobenzo[b][1,4]benzothiazepine-3-carboxamide
Show/Hide
|
C24H19N3O3S
|
1
|
| 1 |
AC50 = 1620 nM
|
|
|
|
CP0908023
|
10-Ethyl-N-(4-methoxybenzyl)-11-oxo-10,11-dihydrodibenzo[b,f][1,4]thiazepine-8-carboxamide 5-(S)-oxide
Show/Hide
|
C24H22N2O4S
|
1
|
| 1 |
AC50 = 2890 nM
|
|
|
|
CP0530680
|
(11S)-5-ethyl-N-[(4-fluorophenyl)methyl]-6,11-dioxobenzo[b][1,4]benzothiazepine-3-carboxamide
Show/Hide
|
C23H19FN2O3S
|
1
|
| 1 |
AC50 = 3240 nM
|
|
|
|
CP0382130
|
(11S)-5-methyl-6,11-dioxo-N-(2-pyrrolidin-1-ylethyl)benzo[b][1,4]benzothiazepine-3-carboxamide
Show/Hide
|
C21H23N3O3S
|
1
|
| 1 |
AC50 = 4570 nM
|
|
|
|
CP0411142
|
(11S)-N-[(4-bromophenyl)methyl]-5-methyl-6,11-dioxobenzo[b][1,4]benzothiazepine-3-carboxamide
Show/Hide
|
C22H17BrN2O3S
|
1
|
| 1 |
AC50 = 4570 nM
|
|
|
|
CP0377527
|
5-ethyl-6,11-diketo-N-p-anisyl-benzo[b][1,4]benzothiazepine-3-carboxamide
Show/Hide
|
C24H22N2O4S
|
1
|
| 1 |
AC50 = 5760 nM
|
|
|
|
CP0480949
|
(11S)-N-[(1R)-1-(4-bromophenyl)ethyl]-5-ethyl-6,11-dioxobenzo[b][1,4]benzothiazepine-3-carboxamide
Show/Hide
|
C24H21BrN2O3S
|
1
|
| 1 |
AC50 = 9130 nM
|
|
|
|
CP0908024
|
N-(4-Chlorobenzyl)-10-methyl-11-oxo-10,11-dihydrodibenzo[b,f][1,4]thiazepine-8-carboxamide 5-(S)-oxide
Show/Hide
|
C22H17ClN2O3S
|
1
|
| 1 |
AC50 = 10200 nM
|
|
|
|
CP0382131
|
(11S)-5-methyl-6,11-dioxo-N-(2-thiophen-2-ylethyl)benzo[b][1,4]benzothiazepine-3-carboxamide
Show/Hide
|
C21H18N2O3S2
|
1
|
| 1 |
AC50 = 12900 nM
|
|
|
|
CP0411140
|
(11S)-5-methyl-6,11-dioxo-N-(pyridin-3-ylmethyl)benzo[b][1,4]benzothiazepine-3-carboxamide
Show/Hide
|
C21H17N3O3S
|
1
|
| 1 |
AC50 = 14500 nM
|
|
|
|
CP0490048
|
5-methyl-6,11-dioxo-N-(2-thiophen-2-ylethyl)benzo[b][1,4]benzothiazepine-3-carboxamide
Show/Hide
|
C21H18N2O3S2
|
1
|
| 1 |
AC50 = 20400 nM
|
|
|
|
CP0380862
|
(11S)-5-ethyl-N-[(1R)-1-naphthalen-2-ylethyl]-6,11-dioxobenzo[b][1,4]benzothiazepine-3-carboxamide
Show/Hide
|
C28H24N2O3S
|
1
|
| 1 |
AC50 = 32400 nM
|
|
|
|
CP0411143
|
(11R)-5-methyl-6,11-dioxo-N-(2-thiophen-2-ylethyl)benzo[b][1,4]benzothiazepine-3-carboxamide
Show/Hide
|
C21H18N2O3S2
|
1
|
| 1 |
AC50 > 77000 nM
|
|
|
|
CP0381126
|
3-[4-[4-[2-[[(6S)-2-amino-4,5,6,7-tetrahydro-1,3-benzothiazol-6-yl]-propylamino]ethyl]piperazin-1-yl]phenyl]phenol
Show/Hide
|
C28H37N5OS
|
1
|
| 1 |
EC50 = 0.1 nM
|
|
|
|
CP0436143
|
1-(2-methoxyphenyl)-4-((1-phenyl-1H-pyrazol-4-yl)methyl)piperazine
Show/Hide
|
C21H24N4O
|
2
|
| 1 |
EC50 = 0.21 nM
|
|
|
| 2 |
Ki = 35 nM
|
|
|
|
CP0374106
|
(-)-6-((2-(4-(biphenyl-4-yl)piperazin-1-yl)ethyl)(propyl)amino)-5,6,7,8-tetrahydronaphthalen-1-ol
Show/Hide
|
C31H39N3O
|
1
|
| 1 |
EC50 = 0.25 nM
|
|
|
|
CP0413985
|
[4-[2-[[(6S)-2-amino-4,5,6,7-tetrahydro-1,3-benzothiazol-6-yl]-propylamino]ethyl]piperazin-1-yl]-(1H-indol-2-yl)methanone
Show/Hide
|
C25H34N6OS
|
1
|
| 1 |
EC50 = 0.26 nM
|
|
|
|
CP0375066
|
[4-[2-[(2-amino-4,5,6,7-tetrahydro-1,3-benzothiazol-6-yl)-propylamino]ethyl]piperazin-1-yl]-(1H-indol-2-yl)methanone
Show/Hide
|
C25H34N6OS
|
1
|
| 1 |
EC50 = 0.26 nM
|
|
|
|
CP0249245
|
4-[5-[[(2S)-5-hydroxy-1,2,3,4-tetrahydronaphthalen-2-yl]-propylamino]pentyl]benzene-1,2-diol
Show/Hide
|
C24H33NO3
|
1
|
| 1 |
EC50 = 0.33 nM
|
|
|
|
CP0104676
|
Benzo[b]thiophene-2-carboxylic acid {4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-butyl}-amide
Show/Hide
|
C24H29N3O2S
|
3
|
| 1 |
EC50 = 0.36 nM
|
|
|
| 2 |
Ki = 0.2344 nM
|
|
|
| 3 |
Ki = 0.27 nM
|
|
|
|
CP0397619
|
(6S)-6-[9-[[(2S)-5-hydroxy-1,2,3,4-tetrahydronaphthalen-2-yl]-propylamino]nonyl-propylamino]-5,6,7,8-tetrahydronaphthalen-1-ol
Show/Hide
|
C35H54N2O2
|
1
|
| 1 |
EC50 = 0.53 nM
|
|
|
|
CP0445313
|
[4-[2-[[(6S)-2-amino-4,5,6,7-tetrahydro-1,3-benzothiazol-6-yl]-propylamino]ethyl]piperazin-1-yl]-(1H-indol-5-yl)methanone
Show/Hide
|
C25H34N6OS
|
1
|
| 1 |
EC50 = 0.56 nM
|
|
|
|
CP0413983
|
(2R,3R)-6-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol
Show/Hide
|
C16H25NO
|
1
|
| 1 |
EC50 = 0.63 nM
|
|
|
|
CP0373532
|
(+)-4-(4-(2-((7-Hydroxy-1,2,3,4-tetrahydronaphthalen-2-yl)(propyl)amino)ethyl)piperazine-1-yl)-quinolin-8-ol
Show/Hide
|
C28H36N4O2
|
1
|
| 1 |
EC50 = 0.74 nM
|
|
|
|
CP0482680
|
4-[5-[[(6S)-2-amino-4,5,6,7-tetrahydro-1,3-benzothiazol-6-yl]-propylamino]pentyl]-2-methoxyphenol
Show/Hide
|
C22H33N3O2S
|
1
|
| 1 |
EC50 = 0.78 nM
|
|
|
|
CP0411950
|
(-)-(S)-N6-(2-(4-(Isoquinolin-1-yl)piperazin-1-yl)ethyl)-N6-propyl-4,5,6,7-tetrahydrobenzo[d]-thiazole-2,6-diamine
Show/Hide
|
C25H34N6S
|
1
|
| 1 |
EC50 = 0.82 nM
|
|
|
|
CP0380255
|
2-[[(6S)-2-amino-4,5,6,7-tetrahydro-1,3-benzothiazol-6-yl]-[2-[4-(7-chloro-1H-indol-6-yl)piperazin-1-yl]ethyl]amino]acetonitrile;2,2,2-trifluoroacetic acid
Show/Hide
|
C25H29ClF3N7O2S
|
1
|
| 1 |
EC50 = 0.84 nM
|
|
|
|
CP0381603
|
[4-[2-[[(6S)-2-amino-4,5,6,7-tetrahydro-1,3-benzothiazol-6-yl]-propylamino]ethyl]piperazin-1-yl]-(1H-indol-3-yl)methanone
Show/Hide
|
C25H34N6OS
|
1
|
| 1 |
EC50 = 0.87 nM
|
|
|
|
CP0452782
|
(6S)-6-[10-[[(2S)-5-hydroxy-1,2,3,4-tetrahydronaphthalen-2-yl]-propylamino]decyl-propylamino]-5,6,7,8-tetrahydronaphthalen-1-ol
Show/Hide
|
C36H56N2O2
|
1
|
| 1 |
EC50 = 0.94 nM
|
|
|
|
CP0072089
|
N-[3-hydroxy-4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]quinoline-3-carboxamide
Show/Hide
|
C25H30N4O3
|
2
|
| 1 |
EC50 = 0.95 nM
|
|
|
| 2 |
IC50 = 47 nM
|
|
|
|
CP0042392
|
(5aR,9aR)-6-Propyl-5,5a,6,7,8,9,9a,10-octahydro-pyrido[2,3-g]quinazolin-2-ylamine
Show/Hide
|
C14H22N4
|
2
|
| 1 |
EC50 = 1 nM
|
|
|
| 2 |
Ki = 0.9333 nM
|
|
|
|
CP0127400
|
(-)-Pramipexole
Show/Hide
|
C10H17N3S
|
4
|
| 1 |
EC50 = 1 nM
|
|
|
| 2 |
Ki = 0.7244 nM
|
|
|
| 3 |
Ki = 0.88 nM
|
|
|
| 4 |
Ki = 38 nM
|
|
|
|
CP0420406
|
[4-(3-carbamoylphenyl)phenyl] N-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl]carbamate
Show/Hide
|
C28H30Cl2N4O3
|
1
|
| 1 |
EC50 = 1 nM
|
|
|
|
CP0416650
|
7-((2-(4-(biphenyl-4-yl)piperazin-1-yl)ethyl)(propyl)amino)-5,6,7,8-tetrahydro naphthalen-2-ol
Show/Hide
|
C31H39N3O
|
1
|
| 1 |
EC50 = 1.03 nM
|
|
|
|
CP0463477
|
2-[5-[[(6S)-2-amino-4,5,6,7-tetrahydro-1,3-benzothiazol-6-yl]-propylamino]pentyl]benzene-1,4-diol
Show/Hide
|
C21H31N3O2S
|
1
|
| 1 |
EC50 = 1.22 nM
|
|
|
|
CP0499931
|
(6S)-6-N-[2-[4-(1H-indol-5-yl)piperazin-1-yl]ethyl]-6-N-propyl-4,5,6,7-tetrahydro-1,3-benzothiazole-2,6-diamine
Show/Hide
|
C24H34N6S
|
1
|
| 1 |
EC50 = 1.26 nM
|
|
|
|
CP0045034
|
N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]pyrazolo[1,5-a]pyridine-2-carboxamide
Show/Hide
|
C23H29N5O2
|
4
|
| 1 |
EC50 = 1.4 nM
|
|
|
| 2 |
Ki = 3.5 nM
|
|
|
| 3 |
Ki = 4.266 nM
|
|
|
| 4 |
Ki = 4.3 nM
|
|
|
|
CP0451725
|
(6S)-6-N-[2-[4-(7-chloro-1H-indol-6-yl)piperazin-1-yl]ethyl]-6-N-propyl-4,5,6,7-tetrahydro-1,3-benzothiazole-2,6-diamine;2,2,2-trifluoroacetic acid
Show/Hide
|
C26H34ClF3N6O2S
|
1
|
| 1 |
EC50 = 1.41 nM
|
|
|
|
CP0434837
|
(4aR,11bR)-4-propyl-2,3,4a,5,6,8,9,11b-octahydroisoindolo[5,6-h][1,4]benzoxazin-10-one
Show/Hide
|
C17H22N2O2
|
2
|
| 1 |
EC50 = 1.413 nM
|
|
|
| 2 |
Ki = 4.169 nM
|
|
|
|
CP0045037
|
Benzofuran-2-carboxylic acid {4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-butyl}-amide
Show/Hide
|
C24H29N3O3
|
2
|
| 1 |
EC50 = 1.5 nM
|
|
|
| 2 |
Ki = 1.122 nM
|
|
|
|
CP0402710
|
(S)-N*6*-[2-(4-Biphenyl-4-yl-piperazin-1-yl)-ethyl]-N*6*-propyl-4,5,6,7-tetrahydro-benzothiazole-2,6-diamine
Show/Hide
|
C28H37N5S
|
1
|
| 1 |
EC50 = 1.51 nM
|
|
|
|
CP0383266
|
(+)-4-(4-(2-((5-Hydroxy-1,2,3,4-tetrahydronaphthalen-2-yl)(propyl)amino)ethyl)piperazin-1-yl)quinolin-8-ol
Show/Hide
|
C28H36N4O2
|
1
|
| 1 |
EC50 = 1.58 nM
|
|
|
|
CP0071762
|
N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]naphthalene-2-carboxamide
Show/Hide
|
C26H31N3O2
|
7
|
| 1 |
EC50 = 1.8 nM
|
|
|
| 2 |
Ki = 0.67 nM
|
|
|
| 3 |
Ki = 0.91 nM
|
|
|
| 4 |
Ki = 0.92 nM
|
|
|
| 5 |
Ki = 1.3 nM
|
|
|
| 6 |
Ki = 1.413 nM
|
|
|
| 7 |
Ki = 4.6 nM
|
|
|
|
CP0394273
|
N-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl]-4-ethynylbenzamide
Show/Hide
|
C23H25Cl2N3O
|
2
|
| 1 |
EC50 = 2 nM
|
|
|
| 2 |
Ki = 0.31 nM
|
|
|
|
CP0393060
|
4-ethynyl-N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]benzamide
Show/Hide
|
C24H29N3O2
|
2
|
| 1 |
EC50 = 2.1 nM
|
|
|
| 2 |
Ki = 1 nM
|
|
|
|
CP0389481
|
S32504 (+)
Show/Hide
|
C16H22N2O2
|
2
|
| 1 |
EC50 = 2.291 nM
|
|
|
| 2 |
Ki = 14.79 nM
|
|
|
|
CP0389488
|
(4aR,11bR)-4-propyl-3,4a,5,6,8,11b-hexahydro-2H-[2]benzofuro[5,6-h][1,4]benzoxazin-10-one
Show/Hide
|
C17H21NO3
|
2
|
| 1 |
EC50 = 2.291 nM
|
|
|
| 2 |
Ki = 7.586 nM
|
|
|
|
CP0157764
|
N-[4-[4-(2-chloro-3-ethylphenyl)piperazin-1-yl]-3-hydroxybutyl]-1H-indole-2-carboxamide
Show/Hide
|
C25H31ClN4O2
|
2
|
| 1 |
EC50 = 2.58 nM
|
|
|
| 2 |
IC50 = 50.5 nM
|
|
|
|
CP0249244
|
4-[5-[[(6S)-2-amino-4,5,6,7-tetrahydro-1,3-benzothiazol-6-yl]-propylamino]pentyl]benzene-1,2-diol
Show/Hide
|
C21H31N3O2S
|
1
|
| 1 |
EC50 = 2.62 nM
|
|
|
|
CP0006107
|
CAS_85760-74-3
Show/Hide
|
C13H21N3
|
9
|
| 1 |
EC50 = 3.1 nM
|
|
|
| 2 |
EC50 = 3.4 nM
|
|
|
| 3 |
EC50 = 5.2 nM
|
|
|
| 4 |
Ki = 0.41 nM
|
|
|
| 5 |
Ki = 15 nM
|
|
|
| 6 |
Ki = 23.99 nM
|
|
|
| 7 |
Ki = 24 nM
|
|
|
| 8 |
Ki = 100 nM
|
|
|
| 9 |
Ki = 420 nM
|
|
|
|
CP0378749
|
4-phenyl-1-((1-phenyl-1H-pyrazol-4-yl)methyl)-1,2,3,6-tetrahydropyridine
Show/Hide
|
C21H21N3
|
2
|
| 1 |
EC50 = 3.3 nM
|
|
|
| 2 |
Ki = 33 nM
|
|
|
|
CP0469127
|
(6S)-6-N-[2-[4-[4-(3-methoxyphenyl)phenyl]piperazin-1-yl]ethyl]-6-N-propyl-4,5,6,7-tetrahydro-1,3-benzothiazole-2,6-diamine
Show/Hide
|
C29H39N5OS
|
1
|
| 1 |
EC50 = 3.42 nM
|
|
|
|
CP0373474
|
N-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl]-3-ethynylbenzamide
Show/Hide
|
C23H25Cl2N3O
|
2
|
| 1 |
EC50 = 3.5 nM
|
|
|
| 2 |
Ki = 0.83 nM
|
|
|
|
CP0408057
|
[4-(3-carbamoylphenyl)phenyl] N-[4-(4-phenylpiperazin-1-yl)butyl]carbamate
Show/Hide
|
C28H32N4O3
|
1
|
| 1 |
EC50 = 3.6 nM
|
|
|
|
CP0413891
|
(6S)-6-N-[2-[4-(5-chloro-1H-indol-4-yl)piperazin-1-yl]ethyl]-6-N-propyl-4,5,6,7-tetrahydro-1,3-benzothiazole-2,6-diamine;2,2,2-trifluoroacetic acid
Show/Hide
|
C26H34ClF3N6O2S
|
1
|
| 1 |
EC50 = 3.93 nM
|
|
|
|
CP0078778
|
4-[2-(dipropylamino)ethyl]-1,3-dihydro-2H-indol-2-one
Show/Hide
|
C16H24N2O
|
3
|
| 1 |
EC50 = 4 nM
|
|
|
| 2 |
EC50 = 10.3 nM
|
|
|
| 3 |
Ki = 36.31 nM
|
|
|
|
CP0479479
|
(4aR,12bR)-4-propyl-3,4a,5,6,8,9,10,12b-octahydro-2H-isoquinolino[6,7-h][1,4]benzoxazin-11-one
Show/Hide
|
C18H24N2O2
|
2
|
| 1 |
EC50 = 4.677 nM
|
|
|
| 2 |
Ki = 38.02 nM
|
|
|
|
CP0224535
|
N-[4-[4-(2-chloro-3-ethylphenyl)piperazin-1-yl]butyl]-1H-indole-2-carboxamide
Show/Hide
|
C25H31ClN4O
|
2
|
| 1 |
EC50 = 4.7 nM
|
|
|
| 2 |
IC50 = 19.1 nM
|
|
|
|
CP0036921
|
3-HYDROXYTYRAMINE HYDROCHLORIDE
Show/Hide
|
C8H11NO2
|
8
|
| 1 |
EC50 = 4.76 nM
|
|
|
| 2 |
EC50 = 5.34 nM
|
|
|
| 3 |
EC50 = 5.8 nM
|
|
|
| 4 |
EC50 = 7.26 nM
|
|
|
| 5 |
EC50 = 7.64 nM
|
|
|
| 6 |
EC50 = 8.57 nM
|
|
|
| 7 |
EC50 = 10.6 nM
|
|
|
| 8 |
Ki = 240 nM
|
|
|
|
CP0049308
|
N-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl]-4-pyridin-2-ylbenzamide
Show/Hide
|
C26H28Cl2N4O
|
1
|
| 1 |
EC50 = 6.31 nM
|
|
|
|
CP0042751
|
(6aR)-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol;hydrate;hydrochloride
Show/Hide
|
C17H17NO2
|
1
|
| 1 |
EC50 = 7 nM
|
|
|
|
CP0136024
|
(R)-3-(4-propylmorpholin-2-yl)phenol
Show/Hide
|
C13H19NO2
|
1
|
| 1 |
EC50 = 8 nM
|
|
|
|
CP0385333
|
2-[[(6S)-2-amino-4,5,6,7-tetrahydro-1,3-benzothiazol-6-yl]-[2-[4-(4-chloro-1H-indol-5-yl)piperazin-1-yl]ethyl]amino]acetonitrile;2,2,2-trifluoroacetic acid
Show/Hide
|
C25H29ClF3N7O2S
|
1
|
| 1 |
EC50 = 10.9 nM
|
|
|
|
CP0109608
|
N-[3-hydroxy-4-(4-naphthalen-1-ylpiperazin-1-yl)butyl]quinoline-3-carboxamide
Show/Hide
|
C28H30N4O2
|
2
|
| 1 |
EC50 = 13 nM
|
|
|
| 2 |
IC50 = 72 nM
|
|
|
|
CP0059097
|
N-[4-[4-(3-chloro-2-methoxyphenyl)piperazin-1-yl]butyl]quinoline-3-carboxamide
Show/Hide
|
C25H29ClN4O2
|
2
|
| 1 |
EC50 = 16 nM
|
|
|
| 2 |
IC50 = 59 nM
|
|
|
|
CP0157763
|
1-(2-chloro-3-ethylphenyl)piperazine
Show/Hide
|
C12H17ClN2
|
2
|
| 1 |
EC50 = 17.9 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0567530
|
(4-phenylphenyl) N-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl]carbamate
Show/Hide
|
C27H30Cl3N3O2
|
1
|
| 1 |
EC50 = 18 nM
|
|
|
|
CP0045182
|
N-[4-(4-naphthalen-1-ylpiperazin-1-yl)butyl]quinoline-3-carboxamide
Show/Hide
|
C28H30N4O
|
2
|
| 1 |
EC50 = 20 nM
|
|
|
| 2 |
IC50 = 7.4 nM
|
|
|
|
CP0427930
|
4-(4-chlorophenyl)-1-((2-methyl-1H-indol-3-yl)methyl)piperidin-4-ol
Show/Hide
|
C21H23ClN2O
|
1
|
| 1 |
EC50 = 20.2 nM
|
|
|
|
CP0460585
|
4-[(E)-5-[[(6S)-2-amino-4,5,6,7-tetrahydro-1,3-benzothiazol-6-yl]-propylamino]pent-1-enyl]-2-methoxyphenol
Show/Hide
|
C22H31N3O2S
|
1
|
| 1 |
EC50 = 20.4 nM
|
|
|
|
CP0544067
|
(4-phenylphenyl) N-[(E)-4-(4-phenylpiperazin-1-yl)but-2-enyl]carbamate
Show/Hide
|
C27H29N3O2
|
1
|
| 1 |
EC50 = 23 nM
|
|
|
|
CP0471129
|
3-(4-Propyl-morpholin-2-yl)-phenol
Show/Hide
|
C13H19NO2
|
1
|
| 1 |
EC50 = 27 nM
|
|
|
|
CP0380694
|
(2R)-2-N-[2-(4-phenylpiperazin-1-yl)ethyl]-2-N-propyl-1,2,3,4-tetrahydronaphthalene-2,7-diamine
Show/Hide
|
C25H36N4
|
1
|
| 1 |
EC50 = 30.3 nM
|
|
|
|
CP0302789
|
N-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl]-4-iodobenzamide
Show/Hide
|
C21H24Cl2IN3O
|
1
|
| 1 |
EC50 = 31.7 nM
|
|
|
|
CP0462501
|
(R)-5-(4-propylmorpholin-2-yl)benzene-1,3-diol
Show/Hide
|
C13H19NO3
|
1
|
| 1 |
EC50 = 32 nM
|
|
|
|
CP0530456
|
2-fluoro-5-(4-propylmorpholin-2-yl)phenol
Show/Hide
|
C13H18FNO2
|
1
|
| 1 |
EC50 = 35 nM
|
|
|
|
CP0421819
|
(R)-2-fluoro-5-(4-propylmorpholin-2-yl)phenol
Show/Hide
|
C13H18FNO2
|
1
|
| 1 |
EC50 = 36 nM
|
|
|
|
CP0527016
|
5-(4-propylmorpholin-2-yl)benzene-1,3-diol
Show/Hide
|
C13H19NO3
|
1
|
| 1 |
EC50 = 37 nM
|
|
|
|
CP0408058
|
[4-(3-carbamoylphenyl)phenyl] N-[(E)-4-[4-(2,3-dichlorophenyl)piperazin-1-yl]but-2-enyl]carbamate
Show/Hide
|
C28H28Cl2N4O3
|
1
|
| 1 |
EC50 = 37.8 nM
|
|
|
|
CP0391183
|
2-amino-4-(4-propylmorpholin-2-yl)phenol
Show/Hide
|
C13H20N2O2
|
1
|
| 1 |
EC50 = 40 nM
|
|
|
|
CP0421766
|
1-((1H-indol-3-yl)methyl)-4-(3,4-dichlorophenyl)piperidin-4-ol
Show/Hide
|
C20H20Cl2N2O
|
1
|
| 1 |
EC50 = 41.5 nM
|
|
|
|
CP0063623
|
N-[(3S)-4-[4-(2-chloro-3-ethylphenyl)piperazin-1-yl]-3-hydroxybutyl]-1H-indole-2-carboxamide
Show/Hide
|
C25H31ClN4O2
|
2
|
| 1 |
EC50 = 46 nM
|
|
|
| 2 |
IC50 = 660 nM
|
|
|
|
CP0082770
|
(-)-3-(1-Propyl-piperidin-3-yl)-phenol
Show/Hide
|
C14H21NO
|
2
|
| 1 |
EC50 = 51.9 nM
|
|
|
| 2 |
Ki = 25.12 nM
|
|
|
|
CP0041232
|
1-((1H-indol-3-yl)methyl)-4-(4-chlorophenyl)piperidin-4-ol
Show/Hide
|
C20H21ClN2O
|
4
|
| 1 |
EC50 = 90.4 nM
|
|
|
| 2 |
Ki = 60 nM
|
|
|
| 3 |
Ki = 87 nM
|
|
|
| 4 |
Ki = 100 nM
|
|
|
|
CP0449015
|
4-(4-chlorophenyl)-1-((1-methyl-1H-indol-3-yl)methyl)piperidin-4-ol
Show/Hide
|
C21H23ClN2O
|
1
|
| 1 |
EC50 = 98.6 nM
|
|
|
|
CP0057834
|
N-[4-(4-naphthalen-1-ylpiperazin-1-yl)butyl]-1H-indole-2-carboxamide
Show/Hide
|
C27H30N4O
|
2
|
| 1 |
EC50 = 140 nM
|
|
|
| 2 |
IC50 = 8 nM
|
|
|
|
CP0065124
|
9H-Fluorene-2-carboxylic acid {(E)-4-[4-(2,3-dichloro-phenyl)-piperazin-1-yl]-but-2-enyl}-amide
Show/Hide
|
C28H27Cl2N3O
|
1
|
| 1 |
EC50 = 173 nM
|
|
|
|
CP0250704
|
N-[4-[4-(2-chloro-3-ethylphenyl)piperazin-1-yl]-3-hydroxybutyl]-1-benzofuran-2-carboxamide
Show/Hide
|
C25H30ClN3O3
|
2
|
| 1 |
EC50 = 196 nM
|
|
|
| 2 |
IC50 = 230 nM
|
|
|
|
CP0409196
|
1-((1H-indol-3-yl)methyl)-4-(2,3-dichlorophenyl)piperidin-4-ol
Show/Hide
|
C20H20Cl2N2O
|
1
|
| 1 |
EC50 = 232 nM
|
|
|
|
CP0495774
|
3-((4-(4-chlorophenyl)-4-methoxypiperidin-1-yl)methyl)-1H-indole
Show/Hide
|
C21H23ClN2O
|
1
|
| 1 |
EC50 = 248 nM
|
|
|
|
CP0445423
|
3-((4-(4-chlorophenyl)-4-methylpiperidin-1-yl)methyl)-1H-indole
Show/Hide
|
C21H23ClN2
|
1
|
| 1 |
EC50 = 347 nM
|
|
|
|
CP0224534
|
N-[4-[4-(2-chloro-3-ethylphenyl)piperazin-1-yl]butyl]-1-benzofuran-2-carboxamide
Show/Hide
|
C25H30ClN3O2
|
2
|
| 1 |
EC50 = 410 nM
|
|
|
| 2 |
IC50 = 18.5 nM
|
|
|
|
CP0530455
|
2-hydroxy-5-(4-propylmorpholin-2-yl)benzamide
Show/Hide
|
C14H20N2O3
|
1
|
| 1 |
EC50 = 427 nM
|
|
|
|
CP0464307
|
3-(4-ethylmorpholin-2-yl)phenol
Show/Hide
|
C12H17NO2
|
1
|
| 1 |
EC50 = 547 nM
|
|
|
|
CP0158026
|
1-butyl-4-(2-chloro-3-ethylphenyl)piperazine
Show/Hide
|
C16H25ClN2
|
2
|
| 1 |
EC50 = 590 nM
|
|
|
| 2 |
IC50 = 63 nM
|
|
|
|
CP0372388
|
4-(4-chlorophenyl)-1-((1-hexyl-1H-indol-3-yl)methyl)piperidin-4-ol
Show/Hide
|
C26H33ClN2O
|
1
|
| 1 |
EC50 = 661 nM
|
|
|
|
CP0224532
|
1-(2-chloro-3-ethylphenyl)-4-methylpiperazine
Show/Hide
|
C13H19ClN2
|
1
|
| 1 |
EC50 = 710 nM
|
|
|
|
CP0510595
|
3-(morpholin-2-yl)phenol
Show/Hide
|
C10H13NO2
|
1
|
| 1 |
EC50 = 864 nM
|
|
|
|
CP0535382
|
3-(4-allylmorpholin-2-yl)phenol
Show/Hide
|
C13H17NO2
|
1
|
| 1 |
EC50 = 1312 nM
|
|
|
|
CP0109326
|
5-Fluoro-1H-indole-2-carboxylic acid {4-[4-(2,3-dichloro-phenyl)-piperazin-1-yl]-butyl}-amide
Show/Hide
|
C23H25Cl2FN4O
|
3
|
| 1 |
EC50 > 10000 nM
|
|
|
| 2 |
IC50 = 52 nM
|
|
|
| 3 |
IC50 = 52.4 nM
|
|
|
|
CP0276368
|
N-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl]quinoxaline-2-carboxamide
Show/Hide
|
C23H25Cl2N5O
|
2
|
| 1 |
EC50 > 10000 nM
|
|
|
| 2 |
IC50 = 26.9 nM
|
|
|
|
CP0348511
|
N-[(E)-4-[4-(2,3-dichlorophenyl)piperazin-1-yl]but-2-enyl]benzamide
Show/Hide
|
C21H23Cl2N3O
|
2
|
| 1 |
EC50 > 10000 nM
|
|
|
| 2 |
IC50 = 7.72 nM
|
|
|
|
CP0378868
|
N-[(Z)-4-[4-(2,3-dichlorophenyl)piperazin-1-yl]but-2-enyl]benzamide
Show/Hide
|
C21H23Cl2N3O
|
2
|
| 1 |
EC50 > 10000 nM
|
|
|
| 2 |
IC50 = 6 nM
|
|
|
|
CP0454011
|
N-[4-[2-(3-hydroxyphenyl)morpholin-4-yl]butyl]acetamide
Show/Hide
|
C16H24N2O3
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0462502
|
(S)-2-fluoro-5-(4-propylmorpholin-2-yl)phenol
Show/Hide
|
C13H18FNO2
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0510579
|
4-bromo-3-(4-propylmorpholin-2-yl)phenol
Show/Hide
|
C13H18BrNO2
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0527015
|
3-hydroxy-5-(4-propylmorpholin-2-yl)benzamide
Show/Hide
|
C14H20N2O3
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0527018
|
(S)-5-(4-propylmorpholin-2-yl)benzene-1,3-diol
Show/Hide
|
C13H19NO3
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0528037
|
3-hydroxy-5-(4-propylmorpholin-2-yl)benzonitrile
Show/Hide
|
C14H18N2O2
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0057840
|
US8748608, 34
Show/Hide
|
C23H26Cl2N4O2
|
2
|
| 1 |
EC50 > 10000 nM
|
|
|
| 2 |
IC50 = 30 nM
|
|
|
|
CP0461615
|
2-chloro-5-(4-propylmorpholin-2-yl)phenol
Show/Hide
|
C13H18ClNO2
|
1
|
| 1 |
EC50 > 688 nM
|
|
|
|
CP0399635
|
2-(3-(4H-1,2,4-triazol-3-yl)phenyl)-4-propylmorpholine
Show/Hide
|
C15H20N4O
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
|
CP0399636
|
3-(4-propylmorpholin-2-yl)benzoic acid
Show/Hide
|
C14H19NO3
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
|
CP0421809
|
N-[3-(4-propylmorpholin-2-yl)phenyl]methanesulfonamide
Show/Hide
|
C14H22N2O3S
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
|
CP0421813
|
1-(2-hydroxy-5-(4-propylmorpholin-2-yl)phenyl)ethanone
Show/Hide
|
C15H21NO3
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
|
CP0428218
|
(3-(4-propylmorpholin-2-yl)phenyl)methanol
Show/Hide
|
C14H21NO2
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
|
CP0428219
|
2-(3-(methylsulfonyl)phenyl)-4-propylmorpholine
Show/Hide
|
C14H21NO3S
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
|
CP0428221
|
2-(3-Methoxy-phenyl)-4-propyl-morpholine
Show/Hide
|
C14H21NO2
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
|
CP0428222
|
3-(4-propylmorpholin-2-yl)benzamide
Show/Hide
|
C14H20N2O2
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
|
CP0454014
|
2-(3-(methylthio)phenyl)-4-propylmorpholine
Show/Hide
|
C14H21NOS
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
|
CP0454016
|
2-phenyl-4-propylmorpholine
Show/Hide
|
C13H19NO
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
|
CP0455081
|
4-(4-propylmorpholin-2-yl)-2-(4H-1,2,4-triazol-4-yl)phenol
Show/Hide
|
C15H20N4O2
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
|
CP0461613
|
2-hydroxy-5-(4-propylmorpholin-2-yl)benzonitrile
Show/Hide
|
C14H18N2O2
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
|
CP0461614
|
4-(4-propylmorpholin-2-yl)phenol
Show/Hide
|
C13H19NO2
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
|
CP0461616
|
2-methyl-3-(4-propylmorpholin-2-yl)phenol
Show/Hide
|
C14H21NO2
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
|
CP0464308
|
methyl 3-(4-propylmorpholin-2-yl)benzoate
Show/Hide
|
C15H21NO3
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
|
CP0513710
|
3-(4-propylmorpholin-2-yl)benzonitrile
Show/Hide
|
C14H18N2O
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
|
CP0527013
|
N-[2-hydroxy-5-(4-propylmorpholin-2-yl)phenyl]methanesulfonamide
Show/Hide
|
C14H22N2O4S
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
|
CP0527014
|
2-(hydroxymethyl)-4-(4-propylmorpholin-2-yl)phenol
Show/Hide
|
C14H21NO3
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
|
CP0528035
|
2-(3-(1H-imidazol-2-yl)phenyl)-4-propylmorpholine
Show/Hide
|
C16H21N3O
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
|
CP0530453
|
4-propyl-2-(3-(trifluoromethoxy)phenyl)morpholine
Show/Hide
|
C14H18F3NO2
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
|
CP0535915
|
3-(4-propylmorpholin-2-yl)benzenamine
Show/Hide
|
C13H20N2O
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
|
CP0063621
|
N-[(3R)-4-[4-(2-chloro-3-ethylphenyl)piperazin-1-yl]-3-hydroxybutyl]-1H-indole-2-carboxamide
Show/Hide
|
C25H31ClN4O2
|
2
|
| 1 |
EC50 > 2200 nM
|
|
|
| 2 |
IC50 = 18.7 nM
|
|
|
|
CP0530454
|
2-(3-Chloro-phenyl)-4-propyl-morpholine
Show/Hide
|
C13H18ClNO
|
1
|
| 1 |
EC50 > 2800 nM
|
|
|
|
CP0454010
|
3-(4-(2-methoxyethyl)morpholin-2-yl)phenol
Show/Hide
|
C13H19NO3
|
1
|
| 1 |
EC50 > 3000 nM
|
|
|
|
CP0039086
|
1-(3-chlorophenyl)-3-(piperidin-2-ylmethyl)imidazolidin-2-one
Show/Hide
|
C15H20ClN3O
|
2
|
| 1 |
EC50 > 3162.28 nM
|
|
|
| 2 |
Ki = 3.981 nM
|
|
|
|
CP0845286
|
1-(2-(azepan-1-yl)ethyl)-3-p-tolylimidazolidin-2-one
Show/Hide
|
C18H27N3O
|
2
|
| 1 |
EC50 > 3162.28 nM
|
|
|
| 2 |
Ki = 125.89 nM
|
|
|
|
CP0845340
|
1-(2-(azepan-1-yl)ethyl)-3-(3-fluorophenyl)imidazolidin-2-one
Show/Hide
|
C17H24FN3O
|
2
|
| 1 |
EC50 > 3162.28 nM
|
|
|
| 2 |
Ki = 15.85 nM
|
|
|
|
CP0846544
|
1-(2-(azepan-1-yl)ethyl)-3-(3,5-dichlorophenyl)imidazolidin-2-one
Show/Hide
|
C17H23Cl2N3O
|
2
|
| 1 |
EC50 > 3162.28 nM
|
|
|
| 2 |
Ki = 1.585 nM
|
|
|
|
CP0846545
|
1-(2-(azepan-1-yl)ethyl)-3-(3-methoxyphenyl)imidazolidin-2-one
Show/Hide
|
C18H27N3O2
|
2
|
| 1 |
EC50 > 3162.28 nM
|
|
|
| 2 |
Ki = 50.12 nM
|
|
|
|
CP0846546
|
1-(2-(azepan-1-yl)ethyl)-3-(pyridin-3-yl)imidazolidin-2-one
Show/Hide
|
C16H24N4O
|
2
|
| 1 |
EC50 > 3162.28 nM
|
|
|
| 2 |
Ki = 79.43 nM
|
|
|
|
CP0846550
|
1-(2-(azepan-1-yl)ethyl)-3-(3-(trifluoromethyl)phenyl)imidazolidin-2-one
Show/Hide
|
C18H24F3N3O
|
2
|
| 1 |
EC50 > 3162.28 nM
|
|
|
| 2 |
Ki = 1 nM
|
|
|
|
CP0849014
|
1-(3-chlorophenyl)-3-((1-methylpiperidin-2-yl)methyl)imidazolidin-2-one
Show/Hide
|
C16H22ClN3O
|
2
|
| 1 |
EC50 > 3162.28 nM
|
|
|
| 2 |
Ki = 3.981 nM
|
|
|
|
CP0849015
|
1-(2-(azepan-1-yl)ethyl)-3-(4-fluorophenyl)imidazolidin-2-one
Show/Hide
|
C17H24FN3O
|
2
|
| 1 |
EC50 > 3162.28 nM
|
|
|
| 2 |
Ki = 251.19 nM
|
|
|
|
CP0849016
|
1-(2-(azepan-1-yl)ethyl)-3-(3-chloro-4-fluorophenyl)imidazolidin-2-one
Show/Hide
|
C17H23ClFN3O
|
2
|
| 1 |
EC50 > 3162.28 nM
|
|
|
| 2 |
Ki = 25.12 nM
|
|
|
|
CP0849018
|
1-(3-chlorophenyl)-3-(piperidin-3-ylmethyl)imidazolidin-2-one
Show/Hide
|
C15H20ClN3O
|
2
|
| 1 |
EC50 > 3162.28 nM
|
|
|
| 2 |
Ki > 630.96 nM
|
|
|
|
CP0853070
|
1-(2-(azepan-1-yl)ethyl)-3-(4-chlorophenyl)imidazolidin-2-one
Show/Hide
|
C17H24ClN3O
|
2
|
| 1 |
EC50 > 3162.28 nM
|
|
|
| 2 |
Ki = 79.43 nM
|
|
|
|
CP0853071
|
1-(2-(azepan-1-yl)ethyl)-3-(pyridin-4-yl)imidazolidin-2-one
Show/Hide
|
C16H24N4O
|
2
|
| 1 |
EC50 > 3162.28 nM
|
|
|
| 2 |
Ki > 630.96 nM
|
|
|
|
CP0853072
|
1-(3-(azepan-1-yl)propyl)-3-(3-chlorophenyl)-1H-imidazol-2(3H)-one
Show/Hide
|
C18H24ClN3O
|
2
|
| 1 |
EC50 > 3162.28 nM
|
|
|
| 2 |
Ki = 125.89 nM
|
|
|
|
CP0853073
|
1-(2-(azepan-1-yl)ethyl)-3-(3-chlorophenyl)imidazolidin-2-one
Show/Hide
|
C17H24ClN3O
|
2
|
| 1 |
EC50 > 3162.28 nM
|
|
|
| 2 |
Ki = 5.012 nM
|
|
|
|
CP0853133
|
1-(piperidin-2-ylmethyl)-3-(3-(trifluoromethyl)phenyl)imidazolidin-2-one
Show/Hide
|
C16H20F3N3O
|
2
|
| 1 |
EC50 > 3162.28 nM
|
|
|
| 2 |
Ki = 0.2512 nM
|
|
|
|
CP0859404
|
1-{2-[5-(3-Chloro-phenyl)-1,1-dioxo-1lambda*6*-[1,2,5]thiadiazolidin-2-yl]-ethyl}-azepane
Show/Hide
|
C16H24ClN3O2S
|
2
|
| 1 |
EC50 > 3162.28 nM
|
|
|
| 2 |
Ki = 316.23 nM
|
|
|
|
CP0859416
|
1-(2-(azepan-1-yl)ethyl)-3-(3-chlorophenyl)-1H-imidazol-2(3H)-one
Show/Hide
|
C17H22ClN3O
|
2
|
| 1 |
EC50 > 3162.28 nM
|
|
|
| 2 |
Ki > 630.96 nM
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|
|
|
CP0859703
|
1-(2-(azepan-1-yl)ethyl)-3-phenylimidazolidin-2-one
Show/Hide
|
C17H25N3O
|
2
|
| 1 |
EC50 > 3162.28 nM
|
|
|
| 2 |
Ki = 63.1 nM
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|
|
|
CP0866954
|
1-(2-(azepan-1-yl)ethyl)-3-m-tolylimidazolidin-2-one
Show/Hide
|
C18H27N3O
|
2
|
| 1 |
EC50 > 3162.28 nM
|
|
|
| 2 |
Ki = 79.43 nM
|
|
|
|
CP0874695
|
1-(3-chlorophenyl)-3-(piperidin-4-ylmethyl)imidazolidin-2-one
Show/Hide
|
C15H20ClN3O
|
2
|
| 1 |
EC50 > 3162.28 nM
|
|
|
| 2 |
Ki > 630.96 nM
|
|
|
|
CP0880337
|
1-(piperidin-2-ylmethyl)-3-(pyridin-3-yl)imidazolidin-2-one
Show/Hide
|
C14H20N4O
|
2
|
| 1 |
EC50 > 3162.28 nM
|
|
|
| 2 |
Ki > 630.96 nM
|
|
|
|
CP0880342
|
1-(2-(azepan-1-yl)ethyl)-3-o-tolylimidazolidin-2-one
Show/Hide
|
C18H27N3O
|
2
|
| 1 |
EC50 > 3162.28 nM
|
|
|
| 2 |
Ki > 630.96 nM
|
|
|
|
CP0239897
|
N-[(3R)-4-[4-(3-chloro-5-ethyl-2-methoxyphenyl)piperazin-1-yl]-3-hydroxybutyl]-1H-indole-2-carboxamide
Show/Hide
|
C26H33ClN4O3
|
2
|
| 1 |
EC50 > 3200 nM
|
|
|
| 2 |
IC50 = 350 nM
|
|
|
|
CP0063610
|
N-[4-[4-(3-chloro-5-ethyl-2-methoxyphenyl)piperazin-1-yl]-3-fluorobutyl]-1-benzofuran-2-carboxamide
Show/Hide
|
C26H31ClFN3O3
|
2
|
| 1 |
EC50 > 4000 nM
|
|
|
| 2 |
IC50 = 490 nM
|
|
|
|
CP0527017
|
(S)-3-(4-propylmorpholin-2-yl)phenol
Show/Hide
|
C13H19NO2
|
1
|
| 1 |
EC50 > 5000 nM
|
|
|
|
CP0063606
|
N-[4-[4-(3-chloro-5-ethyl-2-methoxyphenyl)piperazin-1-yl]-3-fluorobutyl]-1H-indole-2-carboxamide
Show/Hide
|
C26H32ClFN4O2
|
2
|
| 1 |
EC50 > 5400 nM
|
|
|
| 2 |
IC50 = 510 nM
|
|
|
|
CP0391184
|
2-(hydroxymethyl)-5-(4-propylmorpholin-2-yl)phenol
Show/Hide
|
C14H21NO3
|
1
|
| 1 |
EC50 > 5900 nM
|
|
|
|
CP0135682
|
1-butyl-4-(3-chloro-5-ethyl-2-methoxyphenyl)piperazine
Show/Hide
|
C17H27ClN2O
|
2
|
| 1 |
EC50 > 6600 nM
|
|
|
| 2 |
IC50 = 930 nM
|
|
|
|
CP0224533
|
N-[4-[4-(3-chloro-5-ethyl-2-methoxyphenyl)piperazin-1-yl]butyl]-1-benzofuran-2-carboxamide
Show/Hide
|
C26H32ClN3O3
|
2
|
| 1 |
EC50 > 6600 nM
|
|
|
| 2 |
IC50 = 420 nM
|
|
|
|
CP0063619
|
N-[(3S)-4-[4-(3-chloro-5-ethyl-2-methoxyphenyl)piperazin-1-yl]-3-hydroxybutyl]-1H-indole-2-carboxamide
Show/Hide
|
C26H33ClN4O3
|
2
|
| 1 |
EC50 > 6800 nM
|
|
|
| 2 |
IC50 = 1020 nM
|
|
|
|
CP0126478
|
N-[4-[4-(2-chloro-3-ethylphenyl)piperazin-1-yl]-3-fluorobutyl]-1H-indole-2-carboxamide
Show/Hide
|
C25H30ClFN4O
|
2
|
| 1 |
EC50 > 6800 nM
|
|
|
| 2 |
IC50 = 95 nM
|
|
|
|
CP0443872
|
N-[4-[4-(3-chloro-5-ethyl-2-methoxyphenyl)piperazin-1-yl]-3-hydroxybutyl]-1-benzofuran-2-carboxamide
Show/Hide
|
C26H32ClN3O4
|
2
|
| 1 |
EC50 > 7100 nM
|
|
|
| 2 |
IC50 = 950 nM
|
|
|
|
CP0063614
|
N-[4-[4-(2-chloro-3-ethylphenyl)piperazin-1-yl]-3-fluorobutyl]-1-benzofuran-2-carboxamide
Show/Hide
|
C25H29ClFN3O2
|
2
|
| 1 |
EC50 > 7500 nM
|
|
|
| 2 |
IC50 = 450 nM
|
|
|
|
CP0135680
|
N-[4-[4-(3-chloro-5-ethyl-2-methoxyphenyl)piperazin-1-yl]butyl]-1H-indole-2-carboxamide
Show/Hide
|
C26H33ClN4O2
|
2
|
| 1 |
EC50 > 8300 nM
|
|
|
| 2 |
IC50 = 330 nM
|
|
|
|
CP0157762
|
N-[4-[4-(3-chloro-5-ethyl-2-methoxyphenyl)piperazin-1-yl]-3-hydroxybutyl]-1H-indole-2-carboxamide
Show/Hide
|
C26H33ClN4O3
|
2
|
| 1 |
EC50 > 8300 nM
|
|
|
| 2 |
IC50 = 360 nM
|
|
|
|
CP0167921
|
1-(3-chloro-5-ethyl-2-methoxyphenyl)-4-methylpiperazine
Show/Hide
|
C14H21ClN2O
|
2
|
| 1 |
EC50 > 9000 nM
|
|
|
| 2 |
IC50 = 1840 nM
|
|
|
|
CP0378578
|
N-[4-[4-[2-tert-butyl-6-(trifluoromethyl)pyrimidin-4-yl]piperazin-1-yl]butyl]imidazo[1,2-a]pyrazine-2-carboxamide
Show/Hide
|
C24H31F3N8O
|
2
|
| 1 |
IC50 = 0.33 nM
|
|
|
| 2 |
IC50 = 245 nM
|
|
|
|
CP0040671
|
8-[4-(4-fluorophenyl)-4-keto-butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one
Show/Hide
|
C23H26FN3O2
|
3
|
| 1 |
IC50 = 0.36 nM
|
|
|
| 2 |
Ki = 0.12 nM
|
|
|
| 3 |
Ki = 0.25 nM
|
|
|
|
CP0379465
|
N-[4-[4-[2-tert-butyl-6-(trifluoromethyl)pyrimidin-4-yl]piperazin-1-yl]butyl]imidazo[1,2-a]pyridine-2-carboxamide
Show/Hide
|
C25H32F3N7O
|
2
|
| 1 |
IC50 = 1.3 nM
|
|
|
| 2 |
IC50 = 157 nM
|
|
|
|
CP0163132
|
(+)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol
Show/Hide
|
C25H31NO
|
2
|
| 1 |
IC50 = 1.6 nM
|
|
|
| 2 |
Ki = 0.04 nM
|
|
|
|
CP0556149
|
(1R,6S,8S)-6-tert-butyl-3-azapentacyclo[11.8.1.03,8.09,22.016,21]docosa-9,11,13(22),16,18,20-hexaen-6-ol
Show/Hide
|
C25H31NO
|
1
|
| 1 |
IC50 = 1.6 nM
|
|
|
|
CP0386823
|
N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]imidazo[1,2-a]pyridine-2-carboxamide
Show/Hide
|
C23H29N5O2
|
1
|
| 1 |
IC50 = 3 nM
|
|
|
|
CP0410602
|
N-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl]imidazo[1,2-a]pyridine-2-carboxamide
Show/Hide
|
C22H25Cl2N5O
|
1
|
| 1 |
IC50 = 7.2 nM
|
|
|
|
CP0377518
|
1-(2-Fluoro-phenyl)-4-[5-(4-fluoro-phenyl)-pyridin-3-ylmethyl]-piperazine
Show/Hide
|
C22H21F2N3
|
1
|
| 1 |
IC50 = 8 nM
|
|
|
|
CP0386829
|
N-[4-[4-[2-tert-butyl-6-(trifluoromethyl)pyrimidin-4-yl]piperazin-1-yl]butyl]-4-phenylcyclohexane-1-carboxamide
Show/Hide
|
C30H42F3N5O
|
1
|
| 1 |
IC50 = 19 nM
|
|
|
|
CP0397536
|
1-[5-(4-Fluoro-phenyl)-pyridin-3-ylmethyl]-4-phenyl-piperazine
Show/Hide
|
C22H22FN3
|
1
|
| 1 |
IC50 = 33 nM
|
|
|
|
CP0386822
|
N-[4-[4-[2-tert-butyl-6-(trifluoromethyl)pyrimidin-4-yl]piperazin-1-yl]butyl]imidazo[1,2-a]pyrimidine-2-carboxamide
Show/Hide
|
C24H31F3N8O
|
1
|
| 1 |
IC50 = 51 nM
|
|
|
|
CP0397716
|
2-[4-(4'-Fluoro-biphenyl-3-ylmethyl)-piperazin-1-yl]-pyrimidine
Show/Hide
|
C21H21FN4
|
1
|
| 1 |
IC50 = 59 nM
|
|
|
|
CP0448784
|
2-[4-(4'-Methoxy-biphenyl-3-ylmethyl)-piperazin-1-yl]-pyrimidine
Show/Hide
|
C22H24N4O
|
1
|
| 1 |
IC50 = 72 nM
|
|
|
|
CP0776339
|
SID50106618
Show/Hide
|
C18H20Cl2N4
|
1
|
| 1 |
IC50 = 80 nM
|
|
|
|
CP0386824
|
N-[4-(4-quinolin-4-ylpiperazin-1-yl)butyl]imidazo[1,2-a]pyridine-2-carboxamide
Show/Hide
|
C25H28N6O
|
1
|
| 1 |
IC50 = 120 nM
|
|
|
|
CP0443883
|
2-{4-[5-(4-Fluoro-phenyl)-pyridin-3-ylmethyl]-piperazin-1-yl}-pyrimidine
Show/Hide
|
C20H20FN5
|
1
|
| 1 |
IC50 = 150 nM
|
|
|
|
CP0397630
|
2-[4-(3'-Fluoro-biphenyl-3-ylmethyl)-piperazin-1-yl]-pyrimidine
Show/Hide
|
C21H21FN4
|
1
|
| 1 |
IC50 = 200 nM
|
|
|
|
CP0403996
|
2-[4-(3-Thiophen-3-yl-benzyl)-piperazin-1-yl]-pyrimidine
Show/Hide
|
C19H20N4S
|
1
|
| 1 |
IC50 = 200 nM
|
|
|
|
CP0442924
|
1-(4-Fluoro-phenyl)-4-[5-(4-fluoro-phenyl)-pyridin-3-ylmethyl]-piperazine
Show/Hide
|
C22H21F2N3
|
1
|
| 1 |
IC50 = 200 nM
|
|
|
|
CP0386830
|
N-[4-[4-[2-tert-butyl-6-(trifluoromethyl)pyrimidin-4-yl]piperazin-1-yl]butyl]-1H-benzimidazole-2-carboxamide
Show/Hide
|
C25H32F3N7O
|
1
|
| 1 |
IC50 = 208 nM
|
|
|
|
CP0449009
|
1-[5-(4-Fluoro-phenyl)-pyridin-3-ylmethyl]-4-pyridin-2-yl-piperazine
Show/Hide
|
C21H21FN4
|
1
|
| 1 |
IC50 = 300 nM
|
|
|
|
CP0449156
|
2-[4-(2'-Fluoro-biphenyl-3-ylmethyl)-piperazin-1-yl]-pyrimidine
Show/Hide
|
C21H21FN4
|
1
|
| 1 |
IC50 = 320 nM
|
|
|
|
CP0423061
|
4-[5-(4-Fluoro-phenyl)-pyridin-3-ylmethyl]-3,4,5,6-tetrahydro-2H-[1,2']bipyrazinyl
Show/Hide
|
C20H20FN5
|
1
|
| 1 |
IC50 = 480 nM
|
|
|
|
CP0386828
|
N-[4-[4-[2-tert-butyl-6-(trifluoromethyl)pyrimidin-4-yl]piperazin-1-yl]butyl]-6-chloroimidazo[1,2-b]pyridazine-2-carboxamide
Show/Hide
|
C24H30ClF3N8O
|
1
|
| 1 |
IC50 = 637 nM
|
|
|
|
CP0403995
|
2-[4-(2'-Methoxy-biphenyl-3-ylmethyl)-piperazin-1-yl]-pyrimidine
Show/Hide
|
C22H24N4O
|
1
|
| 1 |
IC50 = 710 nM
|
|
|
|
CP0379466
|
N-[4-(4-quinazolin-4-ylpiperazin-1-yl)butyl]imidazo[1,2-a]pyridine-2-carboxamide
Show/Hide
|
C24H27N7O
|
1
|
| 1 |
IC50 = 940 nM
|
|
|
|
CP0406823
|
2-[4-(3'-Methoxy-biphenyl-3-ylmethyl)-piperazin-1-yl]-pyrimidine
Show/Hide
|
C22H24N4O
|
1
|
| 1 |
IC50 = 1100 nM
|
|
|
|
CP0443741
|
2-[4-(9H-Fluoren-4-ylmethyl)-piperazin-1-yl]-pyrimidine
Show/Hide
|
C22H22N4
|
1
|
| 1 |
IC50 = 4000 nM
|
|
|
|
CP0728753
|
SID50107232
Show/Hide
|
C25H33N3O5
|
1
|
| 1 |
IC50 = 5500 nM
|
|
|
|
CP0459319
|
2-[4-(9H-Fluoren-1-ylmethyl)-piperazin-1-yl]-pyrimidine
Show/Hide
|
C22H22N4
|
1
|
| 1 |
IC50 = 5600 nM
|
|
|
|
CP0510875
|
CHEMBL80919
Show/Hide
|
C23H29Cl2N3OS
|
1
|
| 1 |
Ki = 0.02 nM
|
|
|
|
CP0460373
|
(S)-N-(4-(4-Phenylbenzoylamino)butyl)-N-propyl-5-amino-4,5,6,7-tetrahydropyrazolo[1,5-a]pyridine
Show/Hide
|
C27H34N4O
|
2
|
| 1 |
Ki = 0.027 nM
|
|
|
| 2 |
Ki = 0.19 nM
|
|
|
|
CP0446002
|
N-[4-[2-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]ethyl]cyclohexyl]-1H-indole-2-carboxamide
Show/Hide
|
C28H33N5OS
|
1
|
| 1 |
Ki = 0.029 nM
|
|
|
|
CP0420075
|
N-[4-[2-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]ethyl]cyclohexyl]thiophene-2-sulfonamide
Show/Hide
|
C23H30N4O2S3
|
1
|
| 1 |
Ki = 0.043 nM
|
|
|
|
CP0432151
|
1-[4-[2-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]ethyl]cyclohexyl]-3-phenylurea
Show/Hide
|
C26H33N5OS
|
1
|
| 1 |
Ki = 0.043 nM
|
|
|
|
CP0402935
|
N-[4-[2-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]ethyl]cyclohexyl]-N-methylthiophene-2-sulfonamide
Show/Hide
|
C24H32N4O2S3
|
1
|
| 1 |
Ki = 0.046 nM
|
|
|
|
CP0446080
|
CHEMBL3920252
Show/Hide
|
C26H32N4OS
|
1
|
| 1 |
Ki = 0.047 nM
|
|
|
|
CP0446000
|
N-[[4-[[4-(6-chloro-1,2-benzothiazol-3-yl)piperazin-1-yl]methyl]cyclohexyl]methyl]furan-2-carboxamide
Show/Hide
|
C24H29ClN4O2S
|
1
|
| 1 |
Ki = 0.051 nM
|
|
|
|
CP0451760
|
N-[4-[2-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]ethyl]cyclohexyl]propanamide
Show/Hide
|
C22H32N4OS
|
1
|
| 1 |
Ki = 0.052 nM
|
|
|
|
CP0420130
|
1-[4-[2-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]ethyl]cyclohexyl]-3-pyridin-3-ylurea
Show/Hide
|
C25H32N6OS
|
1
|
| 1 |
Ki = 0.055 nM
|
|
|
|
CP0420079
|
N-[4-[2-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]ethyl]cyclohexyl]thiophene-2-carboxamide
Show/Hide
|
C24H30N4OS2
|
1
|
| 1 |
Ki = 0.056 nM
|
|
|
|
CP0388495
|
CHEMBL3933256
Show/Hide
|
C24H31N5O2S2
|
1
|
| 1 |
Ki = 0.058 nM
|
|
|
|
CP0420077
|
ethyl N-[4-[2-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]ethyl]cyclohexyl]carbamate
Show/Hide
|
C22H32N4O2S
|
1
|
| 1 |
Ki = 0.058 nM
|
|
|
|
CP0463824
|
N-[4-[2-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]ethyl]cyclohexyl]-4-methylbenzenesulfonamide
Show/Hide
|
C26H34N4O2S2
|
1
|
| 1 |
Ki = 0.062 nM
|
|
|
|
CP0118796
|
Cariprazine
Show/Hide
|
C21H32Cl2N4O
|
3
|
| 1 |
Ki = 0.085 nM
|
|
|
| 2 |
Ki = 0.096 nM
|
|
|
| 3 |
Ki = 0.27 nM
|
|
|
|
CP0420132
|
N-[4-[2-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]ethyl]cyclohexyl]pyridine-3-carboxamide
Show/Hide
|
C25H31N5OS
|
1
|
| 1 |
Ki = 0.09 nM
|
|
|
|
CP0432149
|
N-[4-[2-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]ethyl]cyclohexyl]methanesulfonamide
Show/Hide
|
C20H30N4O2S2
|
1
|
| 1 |
Ki = 0.095 nM
|
|
|
|
CP0379280
|
2-[3-[4-[1-(benzenesulfonyl)indol-4-yl]piperazin-1-yl]propoxy]benzamide
Show/Hide
|
C28H30N4O4S
|
1
|
| 1 |
Ki = 0.1 nM
|
|
|
|
CP0290487
|
3,4-Dihydro-2-[4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl]-6-(4-pyridyl)isoquinolin-1(2H)-one
Show/Hide
|
C29H34N4O2
|
1
|
| 1 |
Ki = 0.12 nM
|
|
|
|
CP0332114
|
3,4-Dihydro-2-[4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl]-6-(2-thienyl)isoquinolin-1(2H)-one
Show/Hide
|
C28H33N3O2S
|
1
|
| 1 |
Ki = 0.12 nM
|
|
|
|
CP0381103
|
N-[4-[[(1R)-4-ethynylcyclohex-3-en-1-yl]-propylamino]butyl]-4-phenylbenzamide
Show/Hide
|
C28H34N2O
|
2
|
| 1 |
Ki = 0.12 nM
|
|
|
| 2 |
Ki = 4.3 nM
|
|
|
|
CP0044513
|
7-Methoxy-benzofuran-2-carboxylic acid {4-[4-(2,3-dichloro-phenyl)-piperazin-1-yl]-butyl}-amide
Show/Hide
|
C24H27Cl2N3O3
|
1
|
| 1 |
Ki = 0.13 nM
|
|
|
|
CP0432152
|
N-[4-[2-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]ethyl]cyclohexyl]furan-2-carboxamide
Show/Hide
|
C24H30N4O2S
|
1
|
| 1 |
Ki = 0.13 nM
|
|
|
|
CP0375682
|
N-[4-[2-(4-phenylpiperazin-1-yl)ethyl]cyclohexyl]cyclohexanecarboxamide
Show/Hide
|
C25H39N3O
|
1
|
| 1 |
Ki = 0.14 nM
|
|
|
|
CP0512492
|
N-[4-[2-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]ethyl]cyclohexyl]butanamide
Show/Hide
|
C23H34N4OS
|
1
|
| 1 |
Ki = 0.14 nM
|
|
|
|
CP0041783
|
1,1-diethyl-3-[(8alpha)-6-methyl-9,10-didehydroergolin-8-yl]urea
Show/Hide
|
C20H26N4O
|
1
|
| 1 |
Ki = 0.1413 nM
|
|
|
|
CP0465333
|
(2R)-6-[(4-iodophenyl)sulfonylmethyl]-N,N-dipropyl-1,2,3,4-tetrahydronaphthalen-2-amine
Show/Hide
|
C23H30INO2S
|
1
|
| 1 |
Ki = 0.1585 nM
|
|
|
|
CP0053105
|
(S)-3-chloro-5-ethyl-N-((1-ethylpyrrolidin-2-yl)methyl)-6-hydroxy-2-methoxybenzamide
Show/Hide
|
C17H25ClN2O3
|
1
|
| 1 |
Ki = 0.16 nM
|
|
|
|
CP0649608
|
[11C]-(+)-(4aR,10bR)-4-propyl-3,4,4a,5,6,10b-hexahydro-2H-naphtho[1,2-b][1,4]oxazin-9-ol
Show/Hide
|
C15H21NO2
|
1
|
| 1 |
Ki = 0.16 nM
|
|
|
|
CP0432150
|
N-[4-[2-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]ethyl]cyclohexyl]acetamide
Show/Hide
|
C21H30N4OS
|
1
|
| 1 |
Ki = 0.16 nM
|
|
|
|
CP0406353
|
N-[4-[[(1S)-4-ethynylcyclohex-3-en-1-yl]-propylamino]butyl]-4-phenylbenzamide
Show/Hide
|
C28H34N2O
|
2
|
| 1 |
Ki = 0.17 nM
|
|
|
| 2 |
Ki = 1 nM
|
|
|
|
CP0456300
|
1-[4-[2-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]ethyl]cyclohexyl]-3-benzylurea
Show/Hide
|
C27H35N5OS
|
1
|
| 1 |
Ki = 0.18 nM
|
|
|
|
CP0446003
|
N-[4-[2-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]ethyl]cyclohexyl]cyclohexanecarboxamide
Show/Hide
|
C26H38N4OS
|
1
|
| 1 |
Ki = 0.19 nM
|
|
|
|
CP0502038
|
4-(4-aminophenyl)-N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]benzamide
Show/Hide
|
C28H34N4O2
|
1
|
| 1 |
Ki = 0.1995 nM
|
|
|
|
CP0397909
|
N-[[5-(5-ethylsulfonyl-2-methoxyphenyl)-1H-pyrrol-2-yl]methyl]-N-[(4-methylphenyl)methyl]ethanamine
Show/Hide
|
C24H30N2O3S
|
1
|
| 1 |
Ki = 0.1995 nM
|
|
|
|
CP0403727
|
N-[4-[(3aR,9bS)-8-cyano-3,3a,4,9b-tetrahydro-1H-chromeno[3,4-c]pyrrol-2-yl]butyl]-4-(4-aminophenyl)benzamide
Show/Hide
|
C29H30N4O2
|
1
|
| 1 |
Ki = 0.1995 nM
|
|
|
|
CP0162429
|
Biphenyl-4-carboxylic acid {4-[(5-hydroxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-propyl-amino]-butyl}-amide
Show/Hide
|
C30H36N2O2
|
2
|
| 1 |
Ki = 0.1995 nM
|
|
|
| 2 |
Ki = 0.2 nM
|
|
|
|
CP0364137
|
N-[4-[4-(3-hydroxyphenyl)piperazin-1-yl]butyl]naphthalene-2-carboxamide
Show/Hide
|
C25H29N3O2
|
1
|
| 1 |
Ki = 0.2 nM
|
|
|
|
CP0266686
|
N-[4-[(4-ethynylcyclohex-3-en-1-yl)-propylamino]butyl]-4-phenylbenzamide
Show/Hide
|
C28H34N2O
|
1
|
| 1 |
Ki = 0.21 nM
|
|
|
|
CP0142591
|
3,4-Dihydro-6-(2-furyl)-2-[4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl]isoquinolin-1(2H)-one
Show/Hide
|
C28H33N3O3
|
1
|
| 1 |
Ki = 0.21 nM
|
|
|
|
CP0395266
|
4-[3-(1-butyltriazol-4-yl)propoxy]-N-[4-[[(2S)-5-hydroxy-1,2,3,4-tetrahydronaphthalen-2-yl]-propylamino]butyl]-3-methoxybenzamide
Show/Hide
|
C34H49N5O4
|
1
|
| 1 |
Ki = 0.21 nM
|
|
|
|
CP0451765
|
N-[4-[2-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]ethyl]cyclohexyl]cyclopropanecarboxamide
Show/Hide
|
C23H32N4OS
|
1
|
| 1 |
Ki = 0.21 nM
|
|
|
|
CP0460372
|
Biphenyl-4-carboxylic acid {4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-butyl}-amide; oxalic acid
Show/Hide
|
C28H33N3O2
|
2
|
| 1 |
Ki = 0.22 nM
|
|
|
| 2 |
Ki = 0.3 nM
|
|
|
|
CP0407447
|
N-[4-[2-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]ethyl]cyclohexyl]propane-1-sulfonamide
Show/Hide
|
C22H34N4O2S2
|
1
|
| 1 |
Ki = 0.22 nM
|
|
|
|
CP0382591
|
N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]-4-[2-[2-[2-[2-[2-[[4-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butylcarbamoyl]phenyl]methoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxymethyl]benzamide
Show/Hide
|
C56H80N6O10
|
1
|
| 1 |
Ki = 0.23 nM
|
|
|
|
CP0375612
|
N-[4-[[(1R)-4-ethynylcyclohex-3-en-1-yl]-propylamino]butyl]-1-benzothiophene-2-carboxamide
Show/Hide
|
C24H30N2OS
|
1
|
| 1 |
Ki = 0.24 nM
|
|
|
|
CP0432153
|
N-[4-[2-[4-(6-nitro-1,2-benzothiazol-3-yl)piperazin-1-yl]ethyl]cyclohexyl]furan-2-carboxamide
Show/Hide
|
C24H29N5O4S
|
1
|
| 1 |
Ki = 0.24 nM
|
|
|
|
CP0839087
|
5-bromo-N-(4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl)-1H-indole-2-carboxamide
Show/Hide
|
C24H29BrN4O2
|
1
|
| 1 |
Ki = 0.2455 nM
|
|
|
|
CP0291460
|
3,4-Dihydro-2-[4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl]-6-phenylisoquinolin-1(2H)-one
Show/Hide
|
C30H35N3O2
|
1
|
| 1 |
Ki = 0.25 nM
|
|
|
|
CP0437705
|
N-[[5-(5-ethylsulfonyl-2-methoxyphenyl)-1H-pyrrol-2-yl]methyl]-N-[(4-methoxyphenyl)methyl]ethanamine
Show/Hide
|
C24H30N2O4S
|
1
|
| 1 |
Ki = 0.2512 nM
|
|
|
|
CP0717114
|
6-cyano-N-(4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl)-1H-indole-2-carboxamide
Show/Hide
|
C25H29N5O2
|
1
|
| 1 |
Ki = 0.2512 nM
|
|
|
|
CP0043969
|
(1S,5R)-3-(3-{[5-(2,4-Dimethyl-1,3-thiazol-5-yl)-4-methyl-4H-1,2,4-triazol-3-yl]thio}propyl)-1-[4-(trifluoromethyl)phenyl]-3-azabicyclo[3.1.0]hexane
Show/Hide
|
C23H26F3N5S2
|
1
|
| 1 |
Ki = 0.2512 nM
|
|
|
|
CP0057216
|
2-methyl-5-[4-methyl-5-[3-[(1S,5R)-1-[4-(trifluoromethyl)phenyl]-3-azabicyclo[3.1.0]hexan-3-yl]propylsulfanyl]-1,2,4-triazol-3-yl]quinoline
Show/Hide
|
C28H28F3N5S
|
1
|
| 1 |
Ki = 0.2512 nM
|
|
|
|
CP0048038
|
2-(4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl)-2,3,4,5-tetrahydro-1H-benzo[c]azepin-1-one
Show/Hide
|
C25H33N3O2
|
1
|
| 1 |
Ki = 0.27 nM
|
|
|
|
CP0248857
|
7-methoxy-2-(4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl)-2,3,4,5-tetrahydro-1H-benzo[c]azepin-1-one
Show/Hide
|
C26H35N3O3
|
1
|
| 1 |
Ki = 0.27 nM
|
|
|
|
CP0414596
|
N-[4-[2-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]ethyl]cyclohexyl]-2,2,2-trifluoroacetamide
Show/Hide
|
C21H27F3N4OS
|
1
|
| 1 |
Ki = 0.27 nM
|
|
|
|
CP0217047
|
2-[4-(4-(2-Methoxyphenyl)piperazin-1-yl)butyl]-2,3,4,5-tetrahydro-7-(2-thienyl)benzo[c]azepin-1-one
Show/Hide
|
C29H35N3O2S
|
1
|
| 1 |
Ki = 0.29 nM
|
|
|
|
CP0426891
|
N-[4-[4-(N-benzylanilino)piperidin-1-yl]butyl]naphthalene-2-carboxamide
Show/Hide
|
C33H37N3O
|
1
|
| 1 |
Ki = 0.3 nM
|
|
|
|
CP0393676
|
N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]-4-[2-[2-[2-[2-[2-[2-[2-[2-[[4-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butylcarbamoyl]phenyl]methoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxymethyl]benzamide
Show/Hide
|
C62H92N6O13
|
1
|
| 1 |
Ki = 0.3 nM
|
|
|
|
CP0386266
|
(E)-N-[4-[2,3-dihydro-1H-inden-2-yl(propyl)amino]butyl]-3-(4-fluorophenyl)prop-2-enamide
Show/Hide
|
C25H31FN2O
|
1
|
| 1 |
Ki = 0.31 nM
|
|
|
|
CP0444166
|
5-[4-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl]triazol-1-yl]pyrazolo[1,5-a]pyridine
Show/Hide
|
C23H25Cl2N7
|
1
|
| 1 |
Ki = 0.31 nM
|
|
|
|
CP0407445
|
N-[4-[2-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]ethyl]cyclohexyl]-2-methoxyacetamide
Show/Hide
|
C22H32N4O2S
|
1
|
| 1 |
Ki = 0.31 nM
|
|
|
|
CP0407446
|
N-[4-[2-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]ethyl]cyclohexyl]-1H-pyrrole-2-carboxamide
Show/Hide
|
C24H31N5OS
|
1
|
| 1 |
Ki = 0.31 nM
|
|
|
|
CP0417490
|
N-[4-[4-[2-(2-fluoroethoxy)phenyl]piperazin-1-yl]butyl]pyrazolo[1,5-a]pyridine-2-carboxamide
Show/Hide
|
C24H30FN5O2
|
1
|
| 1 |
Ki = 0.31 nM
|
|
|
|
CP0901575
|
N-[4-[4-(2-[18F]fluoroethoxyphenyl)piperazin-1-yl]-butyl]-pyrazolo-[1,5-a]pyridin-2-carboxamide
Show/Hide
|
C24H30FN5O2
|
1
|
| 1 |
Ki = 0.31 nM
|
|
|
|
CP0099825
|
4'-Acetyl-biphenyl-4-carboxylic acid {4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-butyl}-amide
Show/Hide
|
C30H35N3O3
|
1
|
| 1 |
Ki = 0.3162 nM
|
|
|
|
CP0428465
|
N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]-4-(4-methylsulfonylphenyl)benzamide
Show/Hide
|
C29H35N3O4S
|
1
|
| 1 |
Ki = 0.3162 nM
|
|
|
|
CP0506214
|
N-benzyl-N-[[5-(5-ethylsulfonyl-2-methoxyphenyl)-1H-pyrrol-2-yl]methyl]ethanamine
Show/Hide
|
C23H28N2O3S
|
1
|
| 1 |
Ki = 0.3162 nM
|
|
|
|
CP0280047
|
S33084
Show/Hide
|
C29H29N3O2
|
1
|
| 1 |
Ki = 0.3162 nM
|
|
|
|
CP0362589
|
5-[5-[3-[(1S,5R)-1-(4-tert-butylphenyl)-3-azabicyclo[3.1.0]hexan-3-yl]propylsulfanyl]-4-methyl-1,2,4-triazol-3-yl]-4-methyl-1,3-oxazole
Show/Hide
|
C25H33N5OS
|
1
|
| 1 |
Ki = 0.3162 nM
|
|
|
|
CP0945278
|
N-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-3-phenyl-acrylamide oxalic acid
Show/Hide
|
C26H33N3O6
|
1
|
| 1 |
Ki = 0.33 nM
|
|
|
|
CP0506305
|
(E)-N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]-3-phenylprop-2-enamide
Show/Hide
|
C24H31N3O2
|
1
|
| 1 |
Ki = 0.33 nM
|
|
|
|
CP0386381
|
5-[5-[3-[(2R,3R)-2-(2,4-difluorophenyl)-5-azaspiro[2.4]heptan-5-yl]propylsulfanyl]-4-methyl-1,2,4-triazol-3-yl]-4-methyl-1,3-oxazole
Show/Hide
|
C22H25F2N5OS
|
1
|
| 1 |
Ki = 0.3311 nM
|
|
|
|
CP0374901
|
3-(4-Fluoro-phenyl)-N-{4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-butyl}-acrylamide
Show/Hide
|
C24H30FN3O2
|
2
|
| 1 |
Ki = 0.34 nM
|
|
|
| 2 |
Ki = 0.69 nM
|
|
|
|
CP0382590
|
N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]-5-[2-[2-[2-[2-[3-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butylcarbamoyl]pyrazolo[1,5-a]pyridin-5-yl]oxyethoxy]ethoxy]ethoxy]ethoxy]pyrazolo[1,5-a]pyridine-3-carboxamide
Show/Hide
|
C54H72N10O9
|
1
|
| 1 |
Ki = 0.34 nM
|
|
|
|
CP0375779
|
N-[4-[4-(2-methylsulfanylphenyl)piperazin-1-yl]butyl]pyrazolo[1,5-a]pyridine-2-carboxamide
Show/Hide
|
C23H29N5OS
|
1
|
| 1 |
Ki = 0.35 nM
|
|
|
|
CP0717118
|
6-cyano-N-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)butyl)-1H-indole-2-carboxamide
Show/Hide
|
C24H25Cl2N5O
|
1
|
| 1 |
Ki = 0.3548 nM
|
|
|
|
CP0410018
|
(2R,3S)-5-[3-[(5-cyclohexyl-4-methyl-1,2,4-triazol-3-yl)sulfanyl]propyl]-2-[4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptane
Show/Hide
|
C25H33F3N4S
|
1
|
| 1 |
Ki = 0.3548 nM
|
|
|
|
CP0301441
|
3-[4-(4-Phenyl-3,6-dihydro-2H-pyridin-1-yl)-but-1-ynyl]-phenylamine
Show/Hide
|
C21H22N2
|
1
|
| 1 |
Ki = 0.36 nM
|
|
|
|
CP0380643
|
2-[3-[4-methyl-5-[3-[(2R,3S)-2-[4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptan-5-yl]propylsulfanyl]-1,2,4-triazol-3-yl]phenyl]-1,3-oxazole
Show/Hide
|
C28H28F3N5OS
|
1
|
| 1 |
Ki = 0.3631 nM
|
|
|
|
CP0877757
|
4-(6-fluoropyridin-2-yl)-N-{4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl}benzamide
Show/Hide
|
C27H31FN4O2
|
1
|
| 1 |
Ki = 0.37 nM
|
|
|
|
CP0496577
|
3-(4-Methoxy-phenyl)-N-{4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-butyl}-acrylamide
Show/Hide
|
C25H33N3O3
|
1
|
| 1 |
Ki = 0.38 nM
|
|
|
|
CP0717116
|
6-ethynyl-N-(4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl)benzo[b]thiophene-2-carboxamide
Show/Hide
|
C26H29N3O2S
|
1
|
| 1 |
Ki = 0.3802 nM
|
|
|
|
CP0800232
|
5-ethynyl-N-(4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl)benzo[b]thiophene-2-carboxamide
Show/Hide
|
C26H29N3O2S
|
1
|
| 1 |
Ki = 0.389 nM
|
|
|
|
CP0398326
|
4-[4-methyl-5-[3-[(2R,3S)-2-[4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptan-5-yl]propylsulfanyl]-1,2,4-triazol-3-yl]benzamide
Show/Hide
|
C26H28F3N5OS
|
1
|
| 1 |
Ki = 0.389 nM
|
|
|
|
CP0534908
|
N-[(4-chlorophenyl)methyl]-N-[[5-(5-ethylsulfonyl-2-methoxyphenyl)-1H-pyrrol-2-yl]methyl]ethanamine
Show/Hide
|
C23H27ClN2O3S
|
1
|
| 1 |
Ki = 0.3981 nM
|
|
|
|
CP0379000
|
3-[3-[3-[[5-(4-methoxyphenyl)-4-methyl-1,2,4-triazol-3-yl]sulfanyl]propyl]-1,2,4,5-tetrahydro-3-benzazepin-7-yl]-5-methyl-1,2-oxazole
Show/Hide
|
C27H31N5O2S
|
1
|
| 1 |
Ki = 0.3981 nM
|
|
|
|
CP0448096
|
(R)-8-(Benzylamino-methyl)-3,6,7,8-tetrahydro-1H-chromeno[7,8-d]imidazol-2-one
Show/Hide
|
C18H19N3O2
|
1
|
| 1 |
Ki = 0.4 nM
|
|
|
|
CP0507842
|
3-[4-[2-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]ethyl]cyclohexyl]-1,1-dimethylurea
Show/Hide
|
C22H33N5OS
|
1
|
| 1 |
Ki = 0.4 nM
|
|
|
|
CP0387262
|
(6S)-6-[4-[3-[(E)-hydroxyiminomethyl]pyrazolo[1,5-a]pyridin-6-yl]oxybutyl-propylamino]-5,6,7,8-tetrahydronaphthalen-1-ol
Show/Hide
|
C25H32N4O3
|
1
|
| 1 |
Ki = 0.41 nM
|
|
|
|
CP0106454
|
(S)-3-bromo-N-((1-ethylpyrrolidin-2-yl)methyl)-2-hydroxy-5,6-dimethoxybenzamide
Show/Hide
|
C16H23BrN2O4
|
1
|
| 1 |
Ki = 0.42 nM
|
|
|
|
CP0932249
|
3-(4-Bromo-phenyl)-N-{4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-butyl}-acrylamide oxalic acid
Show/Hide
|
C26H32BrN3O6
|
1
|
| 1 |
Ki = 0.43 nM
|
|
|
|
CP0375874
|
N-[4-[[(1S)-4-ethynylcyclohex-3-en-1-yl]-propylamino]butyl]-1-benzothiophene-2-carboxamide
Show/Hide
|
C24H30N2OS
|
1
|
| 1 |
Ki = 0.43 nM
|
|
|
|
CP0674520
|
3-(4-Chloro-phenyl)-N-{4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-butyl}-acrylamide oxalic acid
Show/Hide
|
C26H32ClN3O6
|
1
|
| 1 |
Ki = 0.44 nM
|
|
|
|
CP0380422
|
3-(4-Chloro-phenyl)-N-{4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-butyl}-acrylamide; oxalic acid
Show/Hide
|
C24H30ClN3O2
|
1
|
| 1 |
Ki = 0.44 nM
|
|
|
|
CP0428646
|
N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]-4-[2-[2-[2-[2-[2-[2-[[4-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butylcarbamoyl]phenyl]methoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxymethyl]benzamide
Show/Hide
|
C58H84N6O11
|
1
|
| 1 |
Ki = 0.44 nM
|
|
|
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CP0881177
|
4-(6-fluoropyridin-3-yl)-N-{4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl}benzamide
Show/Hide
|
C27H31FN4O2
|
1
|
| 1 |
Ki = 0.45 nM
|
|
|
|
CP0805511
|
5-cyano-N-(4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl)benzo[b]thiophene-2-carboxamide
Show/Hide
|
C25H28N4O2S
|
1
|
| 1 |
Ki = 0.4571 nM
|
|
|
|
CP0455077
|
5-iodo-2,3-dimethoxy-N-[[(2S)-1-prop-2-enylpyrrolidin-2-yl]methyl]benzamide
Show/Hide
|
C17H23IN2O3
|
1
|
| 1 |
Ki = 0.46 nM
|
|
|
|
CP0861153
|
3-(4-Cyano-phenyl)-N-{4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-butyl}-acrylamide oxalic acid
Show/Hide
|
C27H32N4O6
|
1
|
| 1 |
Ki = 0.46 nM
|
|
|
|
CP0880909
|
3-(3-Chloro-phenyl)-N-{4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-butyl}-acrylamide oxalic acid
Show/Hide
|
C26H32ClN3O6
|
1
|
| 1 |
Ki = 0.46 nM
|
|
|
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CP0446059
|
N-[4-[4-(3-chloro-2-methoxyphenyl)piperazin-1-yl]butyl]tricyclo[8.2.2.24,7]hexadeca-1(13),4,6,10(14),11,15-hexaene-5-carboxamide
Show/Hide
|
C32H38ClN3O2
|
1
|
| 1 |
Ki = 0.46 nM
|
|
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CP0373622
|
(R)-N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl][2.2]-paracyclophane-4-carboxamide
Show/Hide
|
C32H39N3O2
|
1
|
| 1 |
Ki = 0.49 nM
|
|
|
|
CP0043442
|
Benzo[b]thiophene-2-carboxylic acid {4-[4-(2,3-dichloro-phenyl)-piperazin-1-yl]-butyl}-amide
Show/Hide
|
C23H25Cl2N3OS
|
2
|
| 1 |
Ki = 0.5 nM
|
|
|
| 2 |
Ki = 0.5012 nM
|
|
|
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CP0375849
|
(E)-3-(4-Iodo-phenyl)-N-{4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-butyl}-acrylamide
Show/Hide
|
C24H30IN3O2
|
1
|
| 1 |
Ki = 0.5 nM
|
|
|
|
CP0919662
|
N-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-3-pyridin-3-yl-acrylamide oxalic acid
Show/Hide
|
C25H32N4O6
|
1
|
| 1 |
Ki = 0.5 nM
|
|
|
|
CP0920245
|
4-Chloro-N-{4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-butyl}-benzamide oxalic acid
Show/Hide
|
C24H30ClN3O6
|
1
|
| 1 |
Ki = 0.5 nM
|
|
|
|
CP0395381
|
N-[4-[2-[4-(2-chlorophenyl)piperazin-1-yl]ethyl]cyclohexyl]thiophene-2-carboxamide
Show/Hide
|
C23H30ClN3OS
|
1
|
| 1 |
Ki = 0.5 nM
|
|
|
|
CP0291608
|
3,4-Dihydro-6-ethynyl-2-[4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl]isoquinolin-1(2H)-one
Show/Hide
|
C26H31N3O2
|
1
|
| 1 |
Ki = 0.5 nM
|
|
|
|
CP0428642
|
N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]-5-[2-[2-[2-[2-[[3-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butylcarbamoyl]pyrazolo[1,5-a]pyridin-5-yl]methoxy]ethoxy]ethoxy]ethoxy]ethoxymethyl]pyrazolo[1,5-a]pyridine-3-carboxamide
Show/Hide
|
C56H76N10O9
|
1
|
| 1 |
Ki = 0.5 nM
|
|
|
|
CP0232302
|
N-[4-[4-(2-oxo-1,3-dihydroindol-4-yl)piperazin-1-yl]butyl]naphthalene-2-carboxamide
Show/Hide
|
C27H30N4O2
|
1
|
| 1 |
Ki = 0.5 nM
|
|
|
|
CP0552960
|
3-[4-[2-[(5R)-7-chloro-5-methyl-1,2,4,5-tetrahydro-3-benzazepin-3-yl]ethyl]cyclohexyl]-1,1-dimethylurea
Show/Hide
|
C22H34ClN3O
|
1
|
| 1 |
Ki = 0.5 nM
|
|
|
|
CP0080177
|
4-bromo-N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]benzamide
Show/Hide
|
C22H28BrN3O2
|
1
|
| 1 |
Ki = 0.5012 nM
|
|
|
|
CP0508623
|
N-[4-[(2-amino-4,5,6,7-tetrahydro-1,3-benzothiazol-6-yl)-propylamino]butyl]-4-phenylbenzamide
Show/Hide
|
C27H34N4OS
|
1
|
| 1 |
Ki = 0.5012 nM
|
|
|
|
CP0407867
|
(R)-8-(4-(3-(5-fluoro-1H-indol-3-yl)propyl)piperazin-1-yl)-2-methyl-2H-benzo[b][1,4]oxazin-3(4H)-one
Show/Hide
|
C24H27FN4O2
|
1
|
| 1 |
Ki = 0.5012 nM
|
|
|
|
CP0230312
|
N-[4-[(5-cyano-1,2,3,4-tetrahydronaphthalen-2-yl)-propylamino]butyl]-4-phenylbenzamide
Show/Hide
|
C31H35N3O
|
1
|
| 1 |
Ki = 0.5012 nM
|
|
|
|
CP0287045
|
(1S,5R)-3-[3-[[4-methyl-5-(3-methylfuran-2-yl)-1,2,4-triazol-3-yl]sulfanyl]propyl]-1-[4-(trifluoromethyl)phenyl]-3-azabicyclo[3.1.0]hexane
Show/Hide
|
C23H25F3N4OS
|
1
|
| 1 |
Ki = 0.5012 nM
|
|
|
|
CP0768224
|
(1R,5S/1S,5R)-3-(3-{[4-methyl-5-(4-methyl-1,3-oxazol-5-yl)-4H-1,2,4-triazol-3-yl]thio}propyl)-1-[4-(trifluoromethyl)phenyl]-3-azabicyclo[3.1.0]hexane
Show/Hide
|
C22H24F3N5OS
|
1
|
| 1 |
Ki = 0.5012 nM
|
|
|
|
CP0845762
|
[11C]-3-(2-oxo-3-(2-(4-(trifluoromethyl)piperidin-1-yl)ethyl)imidazolidin-1-yl)benzonitrile
Show/Hide
|
C18H21F3N4O
|
1
|
| 1 |
Ki = 0.51 nM
|
|
|
|
CP0261925
|
N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]-9H-fluorene-2-carboxamide
Show/Hide
|
C29H33N3O2
|
1
|
| 1 |
Ki = 0.52 nM
|
|
|
|
CP0846788
|
3-(2-Chloro-phenyl)-N-{4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-butyl}-acrylamide oxalic acid
Show/Hide
|
C26H32ClN3O6
|
1
|
| 1 |
Ki = 0.52 nM
|
|
|
|
CP0214556
|
5-[4-methyl-5-[3-[(2R,3S)-2-[4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptan-5-yl]propylsulfanyl]-1,2,4-triazol-3-yl]pyridine-2-carboxamide
Show/Hide
|
C25H27F3N6OS
|
1
|
| 1 |
Ki = 0.5248 nM
|
|
|
|
CP0465118
|
5-[5-[3-[(2S,3R)-2-(4-fluorophenyl)-5-azaspiro[2.4]heptan-5-yl]propylsulfanyl]-4-methyl-1,2,4-triazol-3-yl]-4-methyl-1,3-oxazole
Show/Hide
|
C22H26FN5OS
|
1
|
| 1 |
Ki = 0.5248 nM
|
|
|
|
CP0436097
|
N-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl]-4-fluorobenzamide
Show/Hide
|
C21H24Cl2FN3O
|
1
|
| 1 |
Ki = 0.53 nM
|
|
|
|
CP0401866
|
(2R,3S)-5-[3-[(4-methyl-5-thiophen-2-yl-1,2,4-triazol-3-yl)sulfanyl]propyl]-2-[4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptane
Show/Hide
|
C23H25F3N4S2
|
1
|
| 1 |
Ki = 0.537 nM
|
|
|
|
CP0535692
|
3-Benzo[1,3]dioxol-4-yl-N-{4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-butyl}-acrylamide
Show/Hide
|
C25H31N3O4
|
1
|
| 1 |
Ki = 0.55 nM
|
|
|
|
CP0503157
|
N-[4-[1,2-diazatricyclo[6.3.1.04,12]dodeca-2,4(12),8,10-tetraen-6-yl(propyl)amino]butyl]-4-phenylbenzamide
Show/Hide
|
C30H34N4O
|
1
|
| 1 |
Ki = 0.55 nM
|
|
|
|
CP0137444
|
3-(2-Methoxy-phenyl)-N-{4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-butyl}-acrylamide
Show/Hide
|
C25H33N3O3
|
1
|
| 1 |
Ki = 0.56 nM
|
|
|
|
CP0300572
|
3-[4-methyl-5-[3-[(2R,3S)-2-[4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptan-5-yl]propylsulfanyl]-1,2,4-triazol-3-yl]benzamide
Show/Hide
|
C26H28F3N5OS
|
1
|
| 1 |
Ki = 0.5623 nM
|
|
|
|
CP0829558
|
5-cyano-N-(4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl)-1H-indole-2-carboxamide
Show/Hide
|
C25H29N5O2
|
1
|
| 1 |
Ki = 0.5754 nM
|
|
|
|
CP0398324
|
5-[5-[3-[(2R,3R)-2-[2-fluoro-4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptan-5-yl]propylsulfanyl]-4-methyl-1,2,4-triazol-3-yl]-4-methyl-1,3-oxazole
Show/Hide
|
C23H25F4N5OS
|
1
|
| 1 |
Ki = 0.5754 nM
|
|
|
|
CP0868273
|
N-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-3-thiophen-2-yl-acrylamide oxalic acid
Show/Hide
|
C24H31N3O6S
|
1
|
| 1 |
Ki = 0.59 nM
|
|
|
|
CP0442092
|
N-[4-[(3-chloro-4,5,6,7-tetrahydropyrazolo[1,5-a]pyridin-5-yl)-propylamino]butyl]-4-phenylbenzamide
Show/Hide
|
C27H33ClN4O
|
1
|
| 1 |
Ki = 0.59 nM
|
|
|
|
CP0387642
|
(6S)-6-[4-[3-[(Z)-hydroxyiminomethyl]pyrazolo[1,5-a]pyridin-5-yl]oxybutyl-propylamino]-5,6,7,8-tetrahydronaphthalen-1-ol
Show/Hide
|
C25H32N4O3
|
1
|
| 1 |
Ki = 0.59 nM
|
|
|
|
CP0444357
|
5-bromo-2,3-dimethoxy-N-[[(2S)-1-prop-2-enylpyrrolidin-2-yl]methyl]benzamide
Show/Hide
|
C17H23BrN2O3
|
1
|
| 1 |
Ki = 0.6 nM
|
|
|
|
CP0845876
|
3-Furan-2-yl-N-{4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-butyl}-acrylamide oxalic acid
Show/Hide
|
C24H31N3O7
|
1
|
| 1 |
Ki = 0.6 nM
|
|
|
|
CP0044536
|
(2R)-7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-2-ol
Show/Hide
|
C16H25NO
|
3
|
| 1 |
Ki = 0.6 nM
|
|
|
| 2 |
Ki = 0.7943 nM
|
|
|
| 3 |
Ki = 2.2 nM
|
|
|
|
CP0397990
|
N-[4-[2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl]cyclohexyl]thiophene-2-carboxamide
Show/Hide
|
C24H33N3O2S
|
1
|
| 1 |
Ki = 0.6 nM
|
|
|
|
CP0372552
|
N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]-3-[2-[2-[2-[2-[3-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butylcarbamoyl]phenoxy]ethoxy]ethoxy]ethoxy]ethoxy]benzamide
Show/Hide
|
C52H72N6O9
|
1
|
| 1 |
Ki = 0.61 nM
|
|
|
|
CP0431629
|
4-[3-(1-butyltriazol-4-yl)propoxy]-N-[4-[[(3R)-6-ethynyl-3,4-dihydro-2H-pyran-3-yl]-propylamino]butyl]-3-methoxybenzamide
Show/Hide
|
C31H45N5O4
|
1
|
| 1 |
Ki = 0.63 nM
|
|
|
|
CP0490264
|
N-(1,3-benzodioxol-5-ylmethyl)-N-[[5-(5-ethylsulfonyl-2-methoxyphenyl)-1H-pyrrol-2-yl]methyl]ethanamine
Show/Hide
|
C24H28N2O5S
|
1
|
| 1 |
Ki = 0.631 nM
|
|
|
|
CP0392240
|
N-[4-[(3aS,9bR)-8-cyano-3,3a,4,9b-tetrahydro-1H-chromeno[3,4-c]pyrrol-2-yl]butyl]-4-phenylbenzamide
Show/Hide
|
C29H29N3O2
|
1
|
| 1 |
Ki = 0.631 nM
|
|
|
|
CP0372580
|
3-(5-methyl-1,2,4-oxadiazol-3-yl)-N-[4-[2-(7-methylsulfonyl-1,2,4,5-tetrahydro-3-benzazepin-3-yl)ethyl]cyclohexyl]benzamide
Show/Hide
|
C29H36N4O4S
|
1
|
| 1 |
Ki = 0.631 nM
|
|
|
|
CP0427205
|
3-[3-[3-[[5-(4-chlorophenyl)-4-methyl-1,2,4-triazol-3-yl]sulfanyl]propyl]-1,2,4,5-tetrahydro-3-benzazepin-7-yl]-5-methyl-1,2-oxazole
Show/Hide
|
C26H28ClN5OS
|
1
|
| 1 |
Ki = 0.631 nM
|
|
|
|
CP0226491
|
1-(3-chlorophenyl)-3-[2-(4,6,7,8-tetrahydrothieno[3,2-c]azepin-5-yl)ethyl]imidazolidin-2-one
Show/Hide
|
C19H22ClN3OS
|
1
|
| 1 |
Ki = 0.631 nM
|
|
|
|
CP0282664
|
(1S,5R)-3-[3-[(4-methyl-5-phenyl-1,2,4-triazol-3-yl)sulfanyl]propyl]-1-[4-(trifluoromethyl)phenyl]-3-azabicyclo[3.1.0]hexane
Show/Hide
|
C24H25F3N4S
|
1
|
| 1 |
Ki = 0.631 nM
|
|
|
|
CP0309386
|
(1S,5R)-3-[3-[[4-methyl-5-(5-methylpyrazin-2-yl)-1,2,4-triazol-3-yl]sulfanyl]propyl]-1-[4-(trifluoromethyl)phenyl]-3-azabicyclo[3.1.0]hexane
Show/Hide
|
C23H25F3N6S
|
1
|
| 1 |
Ki = 0.631 nM
|
|
|
|
CP0100828
|
3-[4-(1,1-Dimethylethyl)phenyl]-8-(3-{[4-methyl-5-(4-methyl-1,3-oxazol-5-yl)-4H-1,2,4-triazol-3-yl]thio}propyl)-8-azabicyclo-[3.2.1]octane
Show/Hide
|
C27H37N5OS
|
1
|
| 1 |
Ki = 0.631 nM
|
|
|
|
CP0397930
|
(E)-N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]-3-thiophen-3-ylprop-2-enamide
Show/Hide
|
C22H29N3O2S
|
1
|
| 1 |
Ki = 0.64 nM
|
|
|
|
CP0467497
|
5-(2-ethoxyethoxy)-N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]pyrazolo[1,5-a]pyridine-3-carboxamide
Show/Hide
|
C27H37N5O4
|
1
|
| 1 |
Ki = 0.66 nM
|
|
|
|
CP0042204
|
1H-Indole-2-carboxylic acid {4-[4-(2,3-dichloro-phenyl)-piperazin-1-yl]-butyl}-amide
Show/Hide
|
C23H26Cl2N4O
|
1
|
| 1 |
Ki = 0.6607 nM
|
|
|
|
CP0420595
|
6-methyl-5-[4-methyl-5-[3-[(2R,3S)-2-[4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptan-5-yl]propylsulfanyl]-1,2,4-triazol-3-yl]pyridine-2-carboxamide
Show/Hide
|
C26H29F3N6OS
|
1
|
| 1 |
Ki = 0.6761 nM
|
|
|
|
CP0475828
|
(E)-N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]-3-naphthalen-2-ylprop-2-enamide
Show/Hide
|
C28H33N3O2
|
1
|
| 1 |
Ki = 0.68 nM
|
|
|
|
CP0717115
|
5-bromo-N-(4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl)benzofuran-2-carboxamide
Show/Hide
|
C24H28BrN3O3
|
1
|
| 1 |
Ki = 0.6918 nM
|
|
|
|
CP0160210
|
N-[4-[4-(2-chlorophenyl)piperazin-1-yl]butyl]naphthalene-2-carboxamide
Show/Hide
|
C25H28ClN3O
|
2
|
| 1 |
Ki = 0.7 nM
|
|
|
| 2 |
Ki = 1 nM
|
|
|
|
CP0899288
|
rac-N-(4-(4-Phenylbenzoylamino)butyl)-N-propyl-5-amino-4,5,6,7-tetrahydropyrazolo[1,5-a]pyridine
Show/Hide
|
C27H34N4O
|
1
|
| 1 |
Ki = 0.71 nM
|
|
|
|
CP0400546
|
4-[3-(1-butyltriazol-4-yl)propoxy]-N-[4-[2,3-dihydro-1H-inden-2-yl(propyl)amino]butyl]-3-methoxybenzamide
Show/Hide
|
C33H47N5O3
|
1
|
| 1 |
Ki = 0.71 nM
|
|
|
|
CP0393754
|
(6S)-6-[propyl(4-pyrazolo[1,5-a]pyridin-6-yloxybutyl)amino]-5,6,7,8-tetrahydronaphthalen-1-ol
Show/Hide
|
C24H31N3O2
|
1
|
| 1 |
Ki = 0.71 nM
|
|
|
|
CP0412946
|
5-hydroxy-8-[4-(4-pyrazolo[1,5-a]pyridin-5-yloxybutyl)piperazin-1-yl]-4H-1,4-benzoxazin-3-one
Show/Hide
|
C23H27N5O4
|
1
|
| 1 |
Ki = 0.71 nM
|
|
|
|
CP0381530
|
1-(3,4-difluorophenyl)imino-3-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]urea
Show/Hide
|
C22H27F2N5O2
|
1
|
| 1 |
Ki = 0.72 nM
|
|
|
|
CP0380644
|
4-methyl-5-[4-methyl-5-[3-[(2R,3S)-2-[4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptan-5-yl]propylsulfanyl]-1,2,4-triazol-3-yl]-1,3-oxazole
Show/Hide
|
C23H26F3N5OS
|
1
|
| 1 |
Ki = 0.7244 nM
|
|
|
|
CP0886323
|
3-(4-Formyl-phenyl)-N-{4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-butyl}-acrylamide oxalic acid
Show/Hide
|
C27H33N3O7
|
1
|
| 1 |
Ki = 0.73 nM
|
|
|
|
CP0420078
|
N-[4-[4-(2-methylphenyl)piperazin-1-yl]butyl]naphthalene-2-carboxamide
Show/Hide
|
C26H31N3O
|
1
|
| 1 |
Ki = 0.73 nM
|
|
|
|
CP0868272
|
N-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-3-(4-nitro-phenyl)-acrylamideoxalic acid
Show/Hide
|
C26H32N4O8
|
1
|
| 1 |
Ki = 0.74 nM
|
|
|
|
CP0805510
|
5-bromo-N-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)butyl)-1H-indole-2-carboxamide
Show/Hide
|
C23H25BrCl2N4O
|
1
|
| 1 |
Ki = 0.7413 nM
|
|
|
|
CP0475827
|
3-(2-Iodo-phenyl)-N-{4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-butyl}-acrylamide
Show/Hide
|
C24H30IN3O2
|
1
|
| 1 |
Ki = 0.75 nM
|
|
|
|
CP0388496
|
3-[4-[2-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]ethyl]cyclohexyl]-1-ethyl-1-methylurea
Show/Hide
|
C23H35N5OS
|
1
|
| 1 |
Ki = 0.78 nM
|
|
|
|
CP0376148
|
N-ethyl-N-[[5-(5-ethylsulfonyl-2-methoxyphenyl)-1H-pyrrol-2-yl]methyl]-2,3-dihydro-1H-inden-1-amine
Show/Hide
|
C25H30N2O3S
|
1
|
| 1 |
Ki = 0.7943 nM
|
|
|
|
CP0439105
|
(1R)-N-ethyl-N-[[5-(5-ethylsulfonyl-2-methoxyphenyl)-1H-pyrrol-2-yl]methyl]-1-phenylethanamine
Show/Hide
|
C24H30N2O3S
|
1
|
| 1 |
Ki = 0.7943 nM
|
|
|
|
CP0447219
|
1-[[5-(5-ethylsulfonyl-2-methoxyphenyl)-1H-pyrrol-2-yl]methyl]-2-(4-methylphenyl)azepane
Show/Hide
|
C27H34N2O3S
|
1
|
| 1 |
Ki = 0.7943 nM
|
|
|
|
CP0383049
|
(2R)-1-[[5-(5-ethylsulfonyl-2-methoxyphenyl)-1H-pyrrol-2-yl]methyl]-2-phenylazepane
Show/Hide
|
C26H32N2O3S
|
1
|
| 1 |
Ki = 0.7943 nM
|
|
|
|
CP0403960
|
N-[4-(8-cyano-3,3a,4,9b-tetrahydro-1H-chromeno[3,4-c]pyrrol-2-yl)butyl]-4-phenylbenzamide
Show/Hide
|
C29H29N3O2
|
1
|
| 1 |
Ki = 0.7943 nM
|
|
|
|
CP0460772
|
4-acetyl-N-[4-[2-(8-cyano-3,3a,4,9b-tetrahydro-1H-chromeno[3,4-c]pyrrol-2-yl)ethyl]phenyl]benzamide
Show/Hide
|
C29H27N3O3
|
1
|
| 1 |
Ki = 0.7943 nM
|
|
|
|
CP0375217
|
N-[4-[(2-amino-5,6,7,8-tetrahydroquinazolin-6-yl)-propylamino]butyl]-4-phenylbenzamide
Show/Hide
|
C28H35N5O
|
1
|
| 1 |
Ki = 0.7943 nM
|
|
|
|
CP0656164
|
4'-chloro-biphenyl-4-sulfonic acid (8-methoxy-3-methyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-yl)-amide
Show/Hide
|
C24H25ClN2O3S
|
1
|
| 1 |
Ki = 0.7943 nM
|
|
|
|
CP0709571
|
4'-chloro-biphenyl-4-sulfonic acid (8-isopropoxy-3-methyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-yl)-amide
Show/Hide
|
C26H29ClN2O3S
|
1
|
| 1 |
Ki = 0.7943 nM
|
|
|
|
CP0449092
|
[3-[2-[4-[[(E)-3-(4-fluorophenyl)prop-2-enoyl]amino]cyclohexyl]ethyl]-1,2,4,5-tetrahydro-3-benzazepin-7-yl] methanesulfonate;hydrochloride
Show/Hide
|
C28H36ClFN2O4S
|
1
|
| 1 |
Ki = 0.7943 nM
|
|
|
|
CP0404763
|
5-methyl-3-[3-[3-[[4-methyl-5-(1-methylpyrrol-2-yl)-1,2,4-triazol-3-yl]sulfanyl]propyl]-1,2,4,5-tetrahydro-3-benzazepin-7-yl]-1,2-oxazole
Show/Hide
|
C25H30N6OS
|
1
|
| 1 |
Ki = 0.7943 nM
|
|
|
|
CP0879663
|
7-(5-methyl-3-isoxazolyl)-3-[3-({4-methyl-5-[3-(methyloxy)-phenyl]-4H-1,2,4-triazol-3-yl}thio)propyl]-2,3,4,5-tetrahydro-1H-3-benzazepine
Show/Hide
|
C27H31N5O2S
|
1
|
| 1 |
Ki = 0.7943 nM
|
|
|
|
CP0466838
|
2-(4-(4-(5-fluoro-1H-indol-3-yl)-5,6-dihydropyridin-1(2H)-yl)butyl)isoindoline-1,3-dione
Show/Hide
|
C25H24FN3O2
|
1
|
| 1 |
Ki = 0.7943 nM
|
|
|
|
CP0079873
|
N-[4-[(5-methoxy-1,2,3,4-tetrahydronaphthalen-2-yl)-propylamino]butyl]-4-phenylbenzamide
Show/Hide
|
C31H38N2O2
|
1
|
| 1 |
Ki = 0.7943 nM
|
|
|
|
CP0063971
|
2-methyl-5-(4-methyl-5-(3-(1-(4-(trifluoromethyl)phenyl)-3-azabicyclo[3.1.0]hexan-3-yl)propylthio)-4H-1,2,4-triazol-3-yl)quinoline
Show/Hide
|
C28H28F3N5S
|
1
|
| 1 |
Ki = 0.7943 nM
|
|
|
|
CP0309385
|
(1S,5R)-3-[3-[[4-methyl-5-(6-methylpyridin-3-yl)-1,2,4-triazol-3-yl]sulfanyl]propyl]-1-[4-(trifluoromethyl)phenyl]-3-azabicyclo[3.1.0]hexane
Show/Hide
|
C24H26F3N5S
|
1
|
| 1 |
Ki = 0.7943 nM
|
|
|
|
CP0658818
|
(1R,5S/1S,5R)-1-(4-tert-Butylphenyl)-3-(3-{[4-methyl-5-(4-methyl-1,3-oxazol-5-yl)-4H-1,2,4-triazol-3-yl]thio}propyl)-3-azabicyclo[3.1.0]hexane
Show/Hide
|
C25H33N5OS
|
1
|
| 1 |
Ki = 0.7943 nM
|
|
|
|
CP0380527
|
(2R,3S)-5-[3-[(4-methyl-5-pyridin-2-yl-1,2,4-triazol-3-yl)sulfanyl]propyl]-2-[4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptane
Show/Hide
|
C24H26F3N5S
|
1
|
| 1 |
Ki = 0.7943 nM
|
|
|
|
CP0404236
|
N-[4-[2-(4-phenylpiperazin-1-yl)ethyl]cyclohexyl]thiophene-2-carboxamide
Show/Hide
|
C23H31N3OS
|
1
|
| 1 |
Ki = 0.8 nM
|
|
|
|
CP0387645
|
(6S)-6-[propyl(4-pyrazolo[1,5-a]pyridin-5-yloxybutyl)amino]-5,6,7,8-tetrahydronaphthalen-1-ol
Show/Hide
|
C24H31N3O2
|
1
|
| 1 |
Ki = 0.8 nM
|
|
|
|
CP0037498
|
4-Cyano-1-methoxy-naphthalene-2-carboxylic acid (1-butyl-pyrrolidin-2-ylmethyl)-amide
Show/Hide
|
C22H27N3O2
|
1
|
| 1 |
Ki = 0.81 nM
|
|
|
|
CP0382046
|
1-[4-[2,3-dihydro-1H-inden-2-yl(propyl)amino]butyl]-3-(4-fluorophenyl)iminourea
Show/Hide
|
C23H29FN4O
|
1
|
| 1 |
Ki = 0.85 nM
|
|
|
|
CP0076352
|
9-Methylsulfanylmethyl-7-propyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-fg]quinoline; compound with methanesulfonic acid
Show/Hide
|
C19H26N2S
|
1
|
| 1 |
Ki = 0.8511 nM
|
|
|
|
CP0440446
|
5-Iodo-benzo[b]thiophene-2-carboxylic acid {4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-butyl}-amide
Show/Hide
|
C24H28IN3O2S
|
1
|
| 1 |
Ki = 0.86 nM
|
|
|
|
CP0396893
|
(NE)-N-[[5-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy]pyrazolo[1,5-a]pyridin-2-yl]methylidene]hydroxylamine
Show/Hide
|
C22H25Cl2N5O2
|
1
|
| 1 |
Ki = 0.86 nM
|
|
|
|
CP0465035
|
N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]-4-[2-[2-[2-[2-[[4-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butylcarbamoyl]phenyl]methoxy]ethoxy]ethoxy]ethoxy]ethoxymethyl]benzamide
Show/Hide
|
C54H76N6O9
|
1
|
| 1 |
Ki = 0.88 nM
|
|
|
|
CP0231667
|
N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]cyclohexanecarboxamide
Show/Hide
|
C22H35N3O2
|
1
|
| 1 |
Ki = 0.9 nM
|
|
|
|
CP0377871
|
(NZ)-N-[1-[4-[2-[(6R)-6-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-2-yl]ethyl]phenyl]ethylidene]hydroxylamine
Show/Hide
|
C26H36N2O
|
1
|
| 1 |
Ki = 1 nM
|
|
|
|
CP0438547
|
Biphenyl-4-carboxylic acid [4-((4aS,10bS)-7-hydroxy-2,3,4a,5,6,10b-hexahydro-1H-benzo[f]quinolin-4-yl)-butyl]-amide
Show/Hide
|
C30H34N2O2
|
1
|
| 1 |
Ki = 1 nM
|
|
|
|
CP0142597
|
N-[4-[2-[(3aR,9bS)-8-cyano-3,3a,4,9b-tetrahydro-1H-chromeno[3,4-c]pyrrol-2-yl]ethyl]phenyl]acetamide
Show/Hide
|
C22H23N3O2
|
1
|
| 1 |
Ki = 1 nM
|
|
|
|
CP0449383
|
N-[4-[2-(8-cyano-3,3a,4,9b-tetrahydro-1H-chromeno[3,4-c]pyrrol-2-yl)ethyl]phenyl]acetamide
Show/Hide
|
C22H23N3O2
|
1
|
| 1 |
Ki = 1 nM
|
|
|
|
CP0505516
|
(5aS,9aS)-6-propyl-5a,7,8,9,9a,10-hexahydro-5H-pyrido[2,3-g]quinazolin-2-amine
Show/Hide
|
C14H22N4
|
1
|
| 1 |
Ki = 1 nM
|
|
|
|
CP0497728
|
8-(Benzylamino-methyl)-3,6,7,8-tetrahydro-1H-chromeno[7,8-d]imidazol-2-one
Show/Hide
|
C18H19N3O2
|
1
|
| 1 |
Ki = 1 nM
|
|
|
|
CP0453062
|
3-Benzo[1,3]dioxol-5-yl-N-{4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-butyl}-acrylamide
Show/Hide
|
C25H31N3O4
|
1
|
| 1 |
Ki = 1 nM
|
|
|
|
CP0540196
|
4-Acetyl-N-{4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-butyl}-benzamide
Show/Hide
|
C24H31N3O3
|
1
|
| 1 |
Ki = 1 nM
|
|
|
|
CP0377766
|
(E)-3-(4-fluorophenyl)-N-[4-[2-(7-methylsulfonyl-1,2,4,5-tetrahydro-3-benzazepin-3-yl)ethyl]cyclohexyl]prop-2-enamide;hydrochloride
Show/Hide
|
C28H36ClFN2O3S
|
1
|
| 1 |
Ki = 1 nM
|
|
|
|
CP0463884
|
CHEMBL2113356
Show/Hide
|
C29H39ClN2O5S
|
1
|
| 1 |
Ki = 1 nM
|
|
|
|
CP0043968
|
7-(2,5-dimethylpyrazol-3-yl)-3-[3-[[4-methyl-5-(2-methylquinolin-5-yl)-1,2,4-triazol-3-yl]sulfanyl]propyl]-1,2,4,5-tetrahydro-3-benzazepine
Show/Hide
|
C31H35N7S
|
3
|
| 1 |
Ki = 1 nM
|
|
|
| 2 |
Ki = 1.585 nM
|
|
|
| 3 |
Ki = 10.23 nM
|
|
|
|
CP0425720
|
3-[3-[3-[[5-(3,4-dichlorophenyl)-4-methyl-1,2,4-triazol-3-yl]sulfanyl]propyl]-1,2,4,5-tetrahydro-3-benzazepin-7-yl]-5-methyl-1,2-oxazole
Show/Hide
|
C26H27Cl2N5OS
|
1
|
| 1 |
Ki = 1 nM
|
|
|
|
CP0899537
|
7-(5-methyl-3-isoxazolyl)-3-(3-{[4-methyl-5-(2-methyl-6-quinolinyl)-4H-1,2,4-triazol-3-yl]thio}propyl)-2,3,4,5-tetrahydro-1H-3-benzazepine
Show/Hide
|
C30H32N6OS
|
1
|
| 1 |
Ki = 1 nM
|
|
|
|
CP0487443
|
2-(5-ethylsulfonyl-2-methoxyphenyl)-5-[(2-phenylpyrrolidin-1-yl)methyl]-1H-pyrrole
Show/Hide
|
C24H28N2O3S
|
1
|
| 1 |
Ki = 1 nM
|
|
|
|
CP0097606
|
3-[2-oxo-3-[2-[4-(trifluoromethyl)piperidin-1-yl]ethyl]imidazolidin-1-yl]benzonitrile
Show/Hide
|
C18H21F3N4O
|
1
|
| 1 |
Ki = 1 nM
|
|
|
|
CP0191648
|
1-(3-iodophenyl)-3-[2-[4-(trifluoromethyl)piperidin-1-yl]ethyl]imidazolidin-2-one
Show/Hide
|
C17H21F3IN3O
|
1
|
| 1 |
Ki = 1 nM
|
|
|
|
CP0062949
|
(1S,5R)-3-(3-{[4-Methyl-5-(4-methyl-1,3-oxazol-5-yl)-4H-1,2,4-triazol-3-yl]thio}propyl)-1-[4-(trifluoromethyl)phenyl]-3-azabicyclo[3.1.0]hexane
Show/Hide
|
C22H24F3N5OS
|
1
|
| 1 |
Ki = 1 nM
|
|
|
|
CP0063970
|
(1S,5R)-3-(3-{[4-Methyl-5-(4-pyridazinyl)-4H-1,2,4-triazol-3-yl]-thio}propyl)-1-[4-(trifluoromethyl)phenyl]-3-azabicyclo[3.1.0]hexane
Show/Hide
|
C22H23F3N6S
|
1
|
| 1 |
Ki = 1 nM
|
|
|
|
CP0244580
|
(1S,5R)-3-(3-{[4-Methyl-5-(2-methyl-3-pyridinyl)-4H-1,2,4-triazol-3-yl]thio}propyl)-1-[4-(trifluoromethyl)phenyl]-3-azabicyclo-[3.1.0]hexane
Show/Hide
|
C24H26F3N5S
|
1
|
| 1 |
Ki = 1 nM
|
|
|
|
CP0375873
|
4-[3-(2-butyltriazol-4-yl)propoxy]-N-[4-[[(1S)-4-ethynylcyclohex-3-en-1-yl]-propylamino]butyl]-3-methoxybenzamide
Show/Hide
|
C32H47N5O3
|
1
|
| 1 |
Ki = 1 nM
|
|
|
|
CP0517451
|
N-[[4-[[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]methyl]cyclohexyl]methyl]furan-2-carboxamide
Show/Hide
|
C24H30N4O2S
|
1
|
| 1 |
Ki = 1 nM
|
|
|
|
CP0472407
|
5-hydroxy-8-[4-[4-[(2-oxo-3,4-dihydro-1H-quinolin-7-yl)oxy]butyl]piperazin-1-yl]-4H-1,4-benzoxazin-3-one
Show/Hide
|
C25H30N4O5
|
1
|
| 1 |
Ki = 1 nM
|
|
|
|
CP0166592
|
N-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl]naphthalene-2-carboxamide
Show/Hide
|
C25H27Cl2N3O
|
2
|
| 1 |
Ki = 1.08 nM
|
|
|
| 2 |
Ki = 7.9 nM
|
|
|
|
CP0264023
|
(S)-3-(Benzylamino-methyl)-2,3-dihydro-benzo[1,4]dioxin-6-ol; oxalic acid
Show/Hide
|
C16H17NO3
|
1
|
| 1 |
Ki = 1.1 nM
|
|
|
|
CP0441826
|
N-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl]-6-fluoropyridine-3-carboxamide
Show/Hide
|
C20H23Cl2FN4O
|
1
|
| 1 |
Ki = 1.1 nM
|
|
|
|
CP0437724
|
(R)-1-Propyl-2,3,10,10a-tetrahydro-1H,4aH-4,9-dioxa-1-aza-phenanthren-6-ol
Show/Hide
|
C14H19NO3
|
1
|
| 1 |
Ki = 1.1 nM
|
|
|
|
CP0307921
|
N-[4-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]butyl]-1-benzothiophene-2-sulfonamide
Show/Hide
|
C24H26FN3O3S2
|
1
|
| 1 |
Ki = 1.1 nM
|
|
|
|
CP0095889
|
N-[4-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]butyl]naphthalene-2-carboxamide
Show/Hide
|
C26H28F3N3O
|
1
|
| 1 |
Ki = 1.1 nM
|
|
|
|
CP0451764
|
N-[4-[2-[4-(6-amino-1,2-benzothiazol-3-yl)piperazin-1-yl]ethyl]cyclohexyl]furan-2-carboxamide
Show/Hide
|
C24H31N5O2S
|
1
|
| 1 |
Ki = 1.1 nM
|
|
|
|
CP0387296
|
5-[4-[[(2S)-5-hydroxy-1,2,3,4-tetrahydronaphthalen-2-yl]-propylamino]butoxy]pyrazolo[1,5-a]pyridine-3-carbaldehyde
Show/Hide
|
C25H31N3O3
|
1
|
| 1 |
Ki = 1.1 nM
|
|
|
|
CP0486717
|
N-[4-[2-[(5R)-7-chloro-5-methyl-1,2,4,5-tetrahydro-3-benzazepin-3-yl]ethyl]cyclohexyl]pyrrolidine-1-carboxamide
Show/Hide
|
C24H36ClN3O
|
1
|
| 1 |
Ki = 1.1 nM
|
|
|
|
CP0041389
|
Benzofuran-2-carboxylic acid {4-[4-(2,3-dichloro-phenyl)-piperazin-1-yl]-butyl}-amide
Show/Hide
|
C23H25Cl2N3O2
|
1
|
| 1 |
Ki = 1.122 nM
|
|
|
|
CP0374346
|
Benzyl-[2-(2-trifluoromethyl-1H-benzoimidazol-4-yloxy)-ethyl]-amine
Show/Hide
|
C17H16F3N3O
|
1
|
| 1 |
Ki = 1.15 nM
|
|
|
|
CP0418809
|
3-(3-Iodo-phenyl)-N-{4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-butyl}-acrylamide
Show/Hide
|
C24H30IN3O2
|
1
|
| 1 |
Ki = 1.2 nM
|
|
|
|
CP0391025
|
N-[4-[2,3-dihydro-1H-inden-2-yl(propyl)amino]butyl]-3-methoxy-4-[3-[1-[8-[4-[3-[2-methoxy-4-[[4-(2-methoxyphenyl)piperazin-1-yl]methyl]phenoxy]propyl]triazol-1-yl]octyl]triazol-4-yl]propoxy]benzamide
Show/Hide
|
C61H84N10O6
|
1
|
| 1 |
Ki = 1.2 nM
|
|
|
|
CP0382589
|
5-(2-ethoxyethoxymethyl)-N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]pyrazolo[1,5-a]pyridine-3-carboxamide
Show/Hide
|
C28H39N5O4
|
1
|
| 1 |
Ki = 1.2 nM
|
|
|
|
CP0386244
|
4-[3-(1-butyltriazol-4-yl)propoxy]-N-[4-[[(2R)-5-hydroxy-1,2,3,4-tetrahydronaphthalen-2-yl]-propylamino]butyl]-3-methoxybenzamide
Show/Hide
|
C34H49N5O4
|
1
|
| 1 |
Ki = 1.2 nM
|
|
|
|
CP0476096
|
(2S,3S)-2-[2-fluoro-4-(trifluoromethyl)phenyl]-5-[3-[(4-methyl-5-pyridin-3-yl-1,2,4-triazol-3-yl)sulfanyl]propyl]-5-azaspiro[2.4]heptane
Show/Hide
|
C24H25F4N5S
|
1
|
| 1 |
Ki = 1.2 nM
|
|
|
|
CP0407443
|
3-[4-[2-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]ethyl]cyclohexyl]-1-methyl-1-phenylurea
Show/Hide
|
C27H35N5OS
|
1
|
| 1 |
Ki = 1.2 nM
|
|
|
|
CP0436910
|
5-[4-[4-(5-hydroxy-3-oxo-4H-1,4-benzoxazin-8-yl)piperazin-1-yl]butoxy]pyrazolo[1,5-a]pyridine-3-carbaldehyde
Show/Hide
|
C24H27N5O5
|
1
|
| 1 |
Ki = 1.2 nM
|
|
|
|
CP0408615
|
N-[4-[4-[2-tert-butyl-6-(trifluoromethyl)pyrimidin-4-yl]piperazin-1-yl]butyl]pyrazolo[1,5-a]pyridine-2-carboxamide
Show/Hide
|
C25H32F3N7O
|
1
|
| 1 |
Ki = 1.2 nM
|
|
|
|
CP0486719
|
8-[4-[2-[(5R)-7-chloro-5-methyl-1,2,4,5-tetrahydro-3-benzazepin-3-yl]ethyl]cyclohexyl]-8-azaspiro[4.5]decane-7,9-dione
Show/Hide
|
C28H39ClN2O2
|
1
|
| 1 |
Ki = 1.2 nM
|
|
|
|
CP0309749
|
N-[4-[4-(2-fluorophenyl)piperazin-1-yl]butyl]naphthalene-2-carboxamide
Show/Hide
|
C25H28FN3O
|
1
|
| 1 |
Ki = 1.23 nM
|
|
|
|
CP0458826
|
6-[(4-methoxyphenyl)sulfanylmethyl]-N,N-dipropyl-1,2,3,4-tetrahydronaphthalen-2-amine
Show/Hide
|
C24H33NOS
|
1
|
| 1 |
Ki = 1.259 nM
|
|
|
|
CP0460096
|
(2R)-6-[(4-methoxyphenyl)sulfonylmethyl]-N,N-dipropyl-1,2,3,4-tetrahydronaphthalen-2-amine
Show/Hide
|
C24H33NO3S
|
1
|
| 1 |
Ki = 1.259 nM
|
|
|
|
CP0409301
|
1-[[5-(5-ethylsulfonyl-2-methoxyphenyl)-1H-pyrrol-2-yl]methyl]-2-phenylazepane
Show/Hide
|
C26H32N2O3S
|
1
|
| 1 |
Ki = 1.259 nM
|
|
|
|
CP0682686
|
N-{4-[2-(7-Cyano-3,4-dihydro-1H-isoquinolin-2-yl)-ethyl]-cyclohexyl}-3-phenyl-acrylamide
Show/Hide
|
C27H32ClN3O
|
1
|
| 1 |
Ki = 1.259 nM
|
|
|
|
CP0374751
|
CHEMBL3084597
Show/Hide
|
C30H38ClN3O5S
|
1
|
| 1 |
Ki = 1.259 nM
|
|
|
|
CP0448546
|
CHEMBL2368633
Show/Hide
|
C29H39ClN2O5S
|
1
|
| 1 |
Ki = 1.259 nM
|
|
|
|
CP0453635
|
CHEMBL2368625
Show/Hide
|
C28H36ClFN2O4S
|
1
|
| 1 |
Ki = 1.259 nM
|
|
|
|
CP0463505
|
CHEMBL3084598
Show/Hide
|
C30H38ClN3O4S
|
1
|
| 1 |
Ki = 1.259 nM
|
|
|
|
CP0507236
|
CHEMBL2368622
Show/Hide
|
C28H36ClFN2O4S
|
1
|
| 1 |
Ki = 1.259 nM
|
|
|
|
CP0524131
|
(E)-3-(2-fluorophenyl)-N-[4-[2-(7-methylsulfonyl-1,2,4,5-tetrahydro-3-benzazepin-3-yl)ethyl]cyclohexyl]prop-2-enamide;hydrochloride
Show/Hide
|
C28H36ClFN2O3S
|
1
|
| 1 |
Ki = 1.259 nM
|
|
|
|
CP0427206
|
5-methyl-3-[3-[3-[(4-methyl-5-thiophen-2-yl-1,2,4-triazol-3-yl)sulfanyl]propyl]-1,2,4,5-tetrahydro-3-benzazepin-7-yl]-1,2-oxazole
Show/Hide
|
C24H27N5OS2
|
1
|
| 1 |
Ki = 1.259 nM
|
|
|
|
CP0427207
|
2-[3-[3-[[5-(1H-indol-2-yl)-4-methyl-1,2,4-triazol-3-yl]sulfanyl]propyl]-1,2,4,5-tetrahydro-3-benzazepin-7-yl]-5-methyl-1,3-oxazole
Show/Hide
|
C28H30N6OS
|
1
|
| 1 |
Ki = 1.259 nM
|
|
|
|
CP0461487
|
5-methyl-3-[3-[3-[[4-methyl-5-(oxan-4-yl)-1,2,4-triazol-3-yl]sulfanyl]propyl]-1,2,4,5-tetrahydro-3-benzazepin-7-yl]-1,2-oxazole
Show/Hide
|
C25H33N5O2S
|
1
|
| 1 |
Ki = 1.259 nM
|
|
|
|
CP0466797
|
5-methyl-3-[3-[3-[[4-methyl-5-(4-methylcyclohexyl)-1,2,4-triazol-3-yl]sulfanyl]propyl]-1,2,4,5-tetrahydro-3-benzazepin-7-yl]-1,2-oxazole
Show/Hide
|
C27H37N5OS
|
1
|
| 1 |
Ki = 1.259 nM
|
|
|
|
CP0399361
|
1-[[5-(5-ethylsulfonyl-2-methoxyphenyl)-1H-pyrrol-2-yl]methyl]-2-phenylpiperidine
Show/Hide
|
C25H30N2O3S
|
1
|
| 1 |
Ki = 1.259 nM
|
|
|
|
CP0267606
|
1-(3,5-dichlorophenyl)-3-[2-(1,3-dihydroisoindol-2-yl)ethyl]imidazolidin-2-one
Show/Hide
|
C19H19Cl2N3O
|
1
|
| 1 |
Ki = 1.259 nM
|
|
|
|
CP0299020
|
1-(3-hydroxyphenyl)-3-[2-[4-(trifluoromethyl)piperidin-1-yl]ethyl]imidazolidin-2-one
Show/Hide
|
C17H22F3N3O2
|
1
|
| 1 |
Ki = 1.259 nM
|
|
|
|
CP0302329
|
1-[2-[(1R,5S)-8-azabicyclo[3.2.1]octan-8-yl]ethyl]-3-(3-chlorophenyl)imidazolidin-2-one
Show/Hide
|
C18H24ClN3O
|
1
|
| 1 |
Ki = 1.259 nM
|
|
|
|
CP0184127
|
N-[4-[(5-bromo-1,2,3,4-tetrahydronaphthalen-2-yl)-propylamino]butyl]-4-phenylbenzamide
Show/Hide
|
C30H35BrN2O
|
1
|
| 1 |
Ki = 1.259 nM
|
|
|
|
CP0275523
|
[6-[4-[(4-phenylbenzoyl)amino]butyl-propylamino]-5,6,7,8-tetrahydronaphthalen-1-yl] methanesulfonate
Show/Hide
|
C31H38N2O4S
|
1
|
| 1 |
Ki = 1.259 nM
|
|
|
|
CP0344188
|
5-[5-[3-[(1S,5R)-1-(4-bromophenyl)-3-azabicyclo[3.1.0]hexan-3-yl]propylsulfanyl]-4-methyl-1,2,4-triazol-3-yl]-2-methylquinoline
Show/Hide
|
C27H28BrN5S
|
1
|
| 1 |
Ki = 1.259 nM
|
|
|
|
CP0916149
|
3-(2,4-Dichloro-phenyl)-N-{4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-butyl}-acrylamide oxalic acid
Show/Hide
|
C26H31Cl2N3O6
|
1
|
| 1 |
Ki = 1.28 nM
|
|
|
|
CP0389512
|
4-ethynyl-N-[4-[4-(4-phenylphenyl)triazol-1-yl]butyl]-N-propylcyclohex-3-en-1-amine
Show/Hide
|
C29H34N4
|
1
|
| 1 |
Ki = 1.3 nM
|
|
|
|
CP0153901
|
2-(4-{3-[4-(2-Propylsulfanyl-phenyl)-piperazin-1-yl]-propoxy}-phenyl)-1H-benzoimidazole
Show/Hide
|
C29H34N4OS
|
1
|
| 1 |
Ki = 1.3 nM
|
|
|
|
CP0142592
|
2-[4-(4-(2-Methoxyphenyl)piperazin-1-yl)butyl]-1-oxo-1,2,3,4-tetrahydroisoquinoline-6-carbonitrile
Show/Hide
|
C25H30N4O2
|
1
|
| 1 |
Ki = 1.3 nM
|
|
|
|
CP0380809
|
[5-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy]pyrazolo[1,5-a]pyridin-2-yl]methanol
Show/Hide
|
C22H26Cl2N4O2
|
1
|
| 1 |
Ki = 1.3 nM
|
|
|
|
CP0356696
|
N-[4-[4-(1H-indol-4-yl)piperazin-1-yl]butyl]naphthalene-2-carboxamide
Show/Hide
|
C27H30N4O
|
1
|
| 1 |
Ki = 1.3 nM
|
|
|
|
CP0356699
|
1-(3-chlorophenyl)-3-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]urea
Show/Hide
|
C22H29ClN4O2
|
1
|
| 1 |
Ki = 1.3 nM
|
|
|
|
CP0875602
|
3-(3,4-Dichloro-phenyl)-N-{4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-butyl}-acrylamide oxalic acid
Show/Hide
|
C26H31Cl2N3O6
|
1
|
| 1 |
Ki = 1.31 nM
|
|
|
|
CP0133068
|
N-[4-[4-(2,3-dimethylphenyl)piperazin-1-yl]butyl]naphthalene-2-carboxamide
Show/Hide
|
C27H33N3O
|
1
|
| 1 |
Ki = 1.33 nM
|
|
|
|
CP0197217
|
5-Iodo-benzofuran-2-carboxylic acid {4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-butyl}-amide
Show/Hide
|
C24H28IN3O3
|
1
|
| 1 |
Ki = 1.4 nM
|
|
|
|
CP0432880
|
5-Iodo-thiophene-2-carboxylic acid {4-[4-(2,3-dichloro-phenyl)-piperazin-1-yl]-butyl}-amide
Show/Hide
|
C19H22Cl2IN3OS
|
1
|
| 1 |
Ki = 1.4 nM
|
|
|
|
CP0423187
|
N-[4-[2-[4-(3-methoxyphenyl)piperazin-1-yl]ethyl]cyclohexyl]thiophene-2-carboxamide
Show/Hide
|
C24H33N3O2S
|
1
|
| 1 |
Ki = 1.4 nM
|
|
|
|
CP0503329
|
N-[4-[2-[4-(2,3-dichlorophenyl)piperazin-1-yl]ethyl]cyclohexyl]furan-2-carboxamide
Show/Hide
|
C23H29Cl2N3O2
|
1
|
| 1 |
Ki = 1.4 nM
|
|
|
|
CP0376122
|
1-[2-[2,3-dihydro-1H-inden-2-yl(propyl)amino]ethyl]-3-(4-fluorophenyl)iminourea
Show/Hide
|
C21H25FN4O
|
1
|
| 1 |
Ki = 1.4 nM
|
|
|
|
CP0381532
|
1-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]-3-(3,4,5-trifluorophenyl)iminourea
Show/Hide
|
C22H26F3N5O2
|
1
|
| 1 |
Ki = 1.4 nM
|
|
|
|
CP0407444
|
3-[4-[2-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]ethyl]cyclohexyl]-1,1-di(propan-2-yl)urea
Show/Hide
|
C26H41N5OS
|
1
|
| 1 |
Ki = 1.4 nM
|
|
|
|
CP0053493
|
(+)-1-Propyl-2,3,10,10a-tetrahydro-1H,4aH-4,9-dioxa-1-aza-phenanthren-6-ol
Show/Hide
|
C14H19NO3
|
1
|
| 1 |
Ki = 1.413 nM
|
|
|
|
CP0398325
|
4-[4-methyl-5-[3-[(2R,3S)-2-[4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptan-5-yl]propylsulfanyl]-1,2,4-triazol-3-yl]thiadiazole
Show/Hide
|
C21H23F3N6S2
|
1
|
| 1 |
Ki = 1.445 nM
|
|
|
|
CP0380480
|
(2R,3S)-5-[3-[[4-methyl-5-(oxan-4-yl)-1,2,4-triazol-3-yl]sulfanyl]propyl]-2-[4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptane
Show/Hide
|
C24H31F3N4OS
|
1
|
| 1 |
Ki = 1.479 nM
|
|
|
|
CP0396198
|
(2S,3S)-2-(2,4-difluorophenyl)-5-[3-[(4-methyl-5-pyridin-3-yl-1,2,4-triazol-3-yl)sulfanyl]propyl]-5-azaspiro[2.4]heptane
Show/Hide
|
C23H25F2N5S
|
1
|
| 1 |
Ki = 1.479 nM
|
|
|
|
CP0742215
|
Isoquinoline-3-carboxylic acid {4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-butyl}-amide oxalic acid
Show/Hide
|
C27H32N4O6
|
1
|
| 1 |
Ki = 1.48 nM
|
|
|
|
CP0393061
|
N-[5-[4-(2,3-dichlorophenyl)piperazin-1-yl]pentyl]-4-ethynylbenzamide
Show/Hide
|
C24H27Cl2N3O
|
1
|
| 1 |
Ki = 1.5 nM
|
|
|
|
CP0500975
|
5-Phenyl-penta-2,4-dienoic acid {4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-butyl}-amide
Show/Hide
|
C26H33N3O2
|
1
|
| 1 |
Ki = 1.5 nM
|
|
|
|
CP0248661
|
2-{4-[3-(4-Phenyl-piperazin-1-yl)-propoxy]-phenyl}-1H-benzoimidazole
Show/Hide
|
C26H28N4O
|
1
|
| 1 |
Ki = 1.5 nM
|
|
|
|
CP0389424
|
5-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy]pyrazolo[1,5-a]pyridine-3-carbonitrile
Show/Hide
|
C22H23Cl2N5O
|
1
|
| 1 |
Ki = 1.5 nM
|
|
|
|
CP0484394
|
1-[4-[2-[(5R)-7-chloro-5-methyl-1,2,4,5-tetrahydro-3-benzazepin-3-yl]ethyl]cyclohexyl]-3-phenylurea
Show/Hide
|
C26H34ClN3O
|
1
|
| 1 |
Ki = 1.5 nM
|
|
|
|
CP0044515
|
6-((4-methoxyphenylsulfonyl)methyl)-N,N-dipropyl-1,2,3,4-tetrahydronaphthalen-2-amine
Show/Hide
|
C24H33NO3S
|
1
|
| 1 |
Ki = 1.585 nM
|
|
|
|
CP0376162
|
1-[[5-(5-ethylsulfonyl-2-methoxyphenyl)-1H-pyrrol-2-yl]methyl]-2-(4-methoxyphenyl)azepane
Show/Hide
|
C27H34N2O4S
|
1
|
| 1 |
Ki = 1.585 nM
|
|
|
|
CP0514494
|
N-[[5-(5-ethylsulfonyl-2-methoxyphenyl)-1H-pyrrol-2-yl]methyl]-N-[(3-methylphenyl)methyl]ethanamine
Show/Hide
|
C24H30N2O3S
|
1
|
| 1 |
Ki = 1.585 nM
|
|
|
|
CP0500190
|
4-[4-methoxy-3-[5-[(2-phenylazepan-1-yl)methyl]-1H-pyrrol-2-yl]phenyl]sulfonylmorpholine
Show/Hide
|
C28H35N3O4S
|
1
|
| 1 |
Ki = 1.585 nM
|
|
|
|
CP0446137
|
N-[4-[2-(8-cyano-3,3a,4,9b-tetrahydro-1H-chromeno[3,4-c]pyrrol-2-yl)ethyl]phenyl]methanesulfonamide
Show/Hide
|
C21H23N3O3S
|
1
|
| 1 |
Ki = 1.585 nM
|
|
|
|
CP0245771
|
[6-[4-[(4-phenylbenzoyl)amino]butyl-propylamino]-5,6,7,8-tetrahydronaphthalen-1-yl] trifluoromethanesulfonate
Show/Hide
|
C31H35F3N2O4S
|
1
|
| 1 |
Ki = 1.585 nM
|
|
|
|
CP0363107
|
N-[4-[(5-chloro-1,2,3,4-tetrahydronaphthalen-2-yl)-propylamino]butyl]-4-phenylbenzamide
Show/Hide
|
C30H35ClN2O
|
1
|
| 1 |
Ki = 1.585 nM
|
|
|
|
CP0741146
|
4'-chloro-biphenyl-4-sulfonic acid (3,8-dimethyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-yl)-amide
Show/Hide
|
C24H25ClN2O2S
|
1
|
| 1 |
Ki = 1.585 nM
|
|
|
|
CP0402973
|
(E)-3-(3-fluorophenyl)-N-[4-[2-(7-methylsulfonyl-1,2,4,5-tetrahydro-3-benzazepin-3-yl)ethyl]cyclohexyl]prop-2-enamide;hydrochloride
Show/Hide
|
C28H36ClFN2O3S
|
1
|
| 1 |
Ki = 1.585 nM
|
|
|
|
CP0509940
|
CHEMBL2368620
Show/Hide
|
C29H36ClN3O3S
|
1
|
| 1 |
Ki = 1.585 nM
|
|
|
|
CP0372576
|
3-[3-[3-[[5-(3-fluorophenyl)-4-methyl-1,2,4-triazol-3-yl]sulfanyl]propyl]-1,2,4,5-tetrahydro-3-benzazepin-7-yl]-5-methyl-1,2-oxazole
Show/Hide
|
C26H28FN5OS
|
1
|
| 1 |
Ki = 1.585 nM
|
|
|
|
CP0372583
|
5-methyl-3-[3-[3-[(4-methyl-5-phenyl-1,2,4-triazol-3-yl)sulfanyl]propyl]-1,2,4,5-tetrahydro-3-benzazepin-7-yl]-1,2-oxazole
Show/Hide
|
C26H29N5OS
|
1
|
| 1 |
Ki = 1.585 nM
|
|
|
|
CP0378819
|
3-[3-[[5-(3,4-difluorophenyl)-4-methyl-1,2,4-triazol-3-yl]sulfanyl]propyl]-7-(2,5-dimethylpyrazol-3-yl)-1,2,4,5-tetrahydro-3-benzazepine
Show/Hide
|
C27H30F2N6S
|
1
|
| 1 |
Ki = 1.585 nM
|
|
|
|
CP0404764
|
2-[3-[3-[[5-(1H-indol-5-yl)-4-methyl-1,2,4-triazol-3-yl]sulfanyl]propyl]-1,2,4,5-tetrahydro-3-benzazepin-7-yl]-5-methyl-1,3-oxazole
Show/Hide
|
C28H30N6OS
|
1
|
| 1 |
Ki = 1.585 nM
|
|
|
|
CP0427208
|
7-(2,5-dimethylpyrazol-3-yl)-3-[4-[[4-methyl-5-(2-methylquinolin-5-yl)-1,2,4-triazol-3-yl]sulfanyl]butan-2-yl]-1,2,4,5-tetrahydro-3-benzazepine
Show/Hide
|
C32H37N7S
|
1
|
| 1 |
Ki = 1.585 nM
|
|
|
|
CP0461488
|
5-methyl-3-[3-[3-[[4-methyl-5-(4-methylphenyl)-1,2,4-triazol-3-yl]sulfanyl]propyl]-1,2,4,5-tetrahydro-3-benzazepin-7-yl]-1,2-oxazole
Show/Hide
|
C27H31N5OS
|
1
|
| 1 |
Ki = 1.585 nM
|
|
|
|
CP0466839
|
3-[3-[3-[[5-(3-chlorophenyl)-4-methyl-1,2,4-triazol-3-yl]sulfanyl]propyl]-1,2,4,5-tetrahydro-3-benzazepin-7-yl]-5-methyl-1,2-oxazole
Show/Hide
|
C26H28ClN5OS
|
1
|
| 1 |
Ki = 1.585 nM
|
|
|
|
CP0505483
|
5-methyl-2-[3-[3-[[4-methyl-5-(1-methylpyrrol-2-yl)-1,2,4-triazol-3-yl]sulfanyl]propyl]-1,2,4,5-tetrahydro-3-benzazepin-7-yl]-1,3-oxazole
Show/Hide
|
C25H30N6OS
|
1
|
| 1 |
Ki = 1.585 nM
|
|
|
|
CP0008601
|
4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)
Show/Hide
|
C21H23ClFNO2
|
14
|
| 1 |
Ki = 1.585 nM
|
|
|
| 2 |
Ki = 2 nM
|
|
|
| 3 |
Ki = 2.2 nM
|
|
|
| 4 |
Ki = 2.3 nM
|
|
|
| 5 |
Ki = 2.6 nM
|
|
|
| 6 |
Ki = 2.7 nM
|
|
|
| 7 |
Ki = 6.3 nM
|
|
|
| 8 |
Ki = 6.4 nM
|
|
|
| 9 |
Ki = 6.8 nM
|
|
|
| 10 |
Ki = 7.5 nM
|
|
|
| 11 |
Ki = 7.943 nM
|
|
|
| 12 |
Ki = 8.318 nM
|
|
|
| 13 |
Ki = 16 nM
|
|
|
| 14 |
Ki = 25 nM
|
|
|
|
CP0033479
|
(chloropromazine) [3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine
Show/Hide
|
C17H19ClN2S
|
3
|
| 1 |
Ki = 1.585 nM
|
|
|
| 2 |
Ki = 3 nM
|
|
|
| 3 |
Ki = 6.9 nM
|
|
|
|
CP0201568
|
1-[2-(1,3-dihydroisoindol-2-yl)ethyl]-3-[3-(trifluoromethoxy)phenyl]imidazolidin-2-one
Show/Hide
|
C20H20F3N3O2
|
1
|
| 1 |
Ki = 1.585 nM
|
|
|
|
CP0266807
|
1-(3-chlorophenyl)-3-[2-[4-(trifluoromethyl)piperidin-1-yl]ethyl]imidazolidin-2-one
Show/Hide
|
C17H21ClF3N3O
|
1
|
| 1 |
Ki = 1.585 nM
|
|
|
|
CP0267609
|
1-(3-chloro-5-fluorophenyl)-3-[2-(1,3-dihydroisoindol-2-yl)ethyl]imidazolidin-2-one
Show/Hide
|
C19H19ClFN3O
|
1
|
| 1 |
Ki = 1.585 nM
|
|
|
|
CP0089667
|
CHEMBL558058
Show/Hide
|
C23H32F3N3O
|
1
|
| 1 |
Ki = 1.585 nM
|
|
|
|
CP0130211
|
4-phenyl-N-[4-[propyl(1,2,3,4-tetrahydronaphthalen-2-yl)amino]butyl]benzamide
Show/Hide
|
C30H36N2O
|
1
|
| 1 |
Ki = 1.585 nM
|
|
|
|
CP0346424
|
(1S,5R)-3-[3-[(4-methyl-5-pyrimidin-5-yl-1,2,4-triazol-3-yl)sulfanyl]propyl]-1-[4-(trifluoromethyl)phenyl]-3-azabicyclo[3.1.0]hexane
Show/Hide
|
C22H23F3N6S
|
1
|
| 1 |
Ki = 1.585 nM
|
|
|
|
CP0400288
|
5-(3-fluoropropyl)-2,3-dimethoxy-N-[[(2S)-1-prop-2-enylpyrrolidin-2-yl]methyl]benzamide
Show/Hide
|
C20H29FN2O3
|
1
|
| 1 |
Ki = 1.6 nM
|
|
|
|
CP0415946
|
N-[4-[4-(5-tricyclo[8.2.2.24,7]hexadeca-1(13),4,6,10(14),11,15-hexaenyl)piperazin-1-yl]butyl]-1-benzothiophene-2-carboxamide
Show/Hide
|
C33H37N3OS
|
1
|
| 1 |
Ki = 1.6 nM
|
|
|
|
CP0291606
|
6-fluoro-2-(4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl)-3,4-dihydroisoquinolin-1(2H)-one
Show/Hide
|
C24H30FN3O2
|
1
|
| 1 |
Ki = 1.6 nM
|
|
|
|
CP0386241
|
4-[3-(1-butyltriazol-4-yl)propoxy]-N-[4-[2-(8-hydroxy-2-oxo-1H-quinolin-5-yl)ethyl-propylamino]butyl]-3-methoxybenzamide
Show/Hide
|
C35H48N6O5
|
1
|
| 1 |
Ki = 1.6 nM
|
|
|
|
CP0356698
|
N-[4-[4-[3-(methanesulfonamido)phenyl]piperazin-1-yl]butyl]naphthalene-2-carboxamide
Show/Hide
|
C26H32N4O3S
|
1
|
| 1 |
Ki = 1.6 nM
|
|
|
|
CP0451761
|
N-[4-[2-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]ethyl]cyclohexyl]morpholine-4-carboxamide
Show/Hide
|
C24H35N5O2S
|
1
|
| 1 |
Ki = 1.6 nM
|
|
|
|
CP0387293
|
6-[4-[[(2S)-5-hydroxy-1,2,3,4-tetrahydronaphthalen-2-yl]-propylamino]butoxy]pyrazolo[1,5-a]pyridine-3-carbaldehyde
Show/Hide
|
C25H31N3O3
|
1
|
| 1 |
Ki = 1.6 nM
|
|
|
|
CP0458291
|
4-[3-(1-butyltriazol-4-yl)propoxy]-N-[3-[4-(8-hydroxy-2-oxo-1H-quinolin-5-yl)-1,4-diazepan-1-yl]propyl]-3-methoxybenzamide
Show/Hide
|
C34H45N7O5
|
1
|
| 1 |
Ki = 1.6 nM
|
|
|
|
CP0717117
|
4-chloro-N-(4-(4-(2-chlorophenyl)piperazin-1-yl)butyl)benzamide
Show/Hide
|
C21H25Cl2N3O
|
1
|
| 1 |
Ki = 1.698 nM
|
|
|
|
CP0079495
|
9H-Fluorene-2-carboxylic acid {4-[4-(2,3-dichloro-phenyl)-piperazin-1-yl]-butyl}-amide
Show/Hide
|
C28H29Cl2N3O
|
1
|
| 1 |
Ki = 1.7 nM
|
|
|
|
CP0057510
|
2-(4-{3-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-propoxy}-phenyl)-1H-benzoimidazole
Show/Hide
|
C27H30N4O2
|
1
|
| 1 |
Ki = 1.7 nM
|
|
|
|
CP0142590
|
2-(4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl)-3,4-dihydroisoquinolin-1(2H)-one
Show/Hide
|
C24H31N3O2
|
1
|
| 1 |
Ki = 1.7 nM
|
|
|
|
CP0405813
|
4-[4-(2,3-dichlorophenyl)piperazin-1-yl]-N-(3-formylpyrazolo[1,5-a]pyridin-5-yl)butanamide
Show/Hide
|
C22H23Cl2N5O2
|
1
|
| 1 |
Ki = 1.7 nM
|
|
|
|
CP0453253
|
2-Oxo-2H-chromene-3-carboxylic acid {4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-butyl}-amide
Show/Hide
|
C25H29N3O4
|
2
|
| 1 |
Ki = 1.8 nM
|
|
|
| 2 |
Ki = 60.1 nM
|
|
|
|
CP0899590
|
Thiophene-2-carboxylic acid (4-{2-[4-(2,3-dichloro-phenyl)-piperazin-1-yl]-ethyl}-cyclohexyl)-amide
Show/Hide
|
C23H29Cl2N3OS
|
1
|
| 1 |
Ki = 1.8 nM
|
|
|
|
CP0400542
|
N-[4-[2,3-dihydro-1H-inden-2-yl(propyl)amino]butyl]-4-[3-[1-[8-[4-[3-[4-[4-[2,3-dihydro-1H-inden-2-yl(propyl)amino]butylcarbamoyl]-2-methoxyphenoxy]propyl]triazol-1-yl]octyl]triazol-4-yl]propoxy]-3-methoxybenzamide
Show/Hide
|
C66H92N10O6
|
1
|
| 1 |
Ki = 1.8 nM
|
|
|
|
CP0489218
|
[4-(4-chlorophenyl)-1-[4-(4-fluorophenyl)-4-oxobutyl]piperidin-4-yl] 3-[1-[8-[4-[3-[4-(4-chlorophenyl)-1-[4-(4-fluorophenyl)-4-oxobutyl]piperidin-4-yl]oxy-3-oxopropyl]triazol-1-yl]octyl]triazol-4-yl]propanoate
Show/Hide
|
C60H70Cl2F2N8O6
|
1
|
| 1 |
Ki = 1.8 nM
|
|
|
|
CP0071764
|
N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]morpholine-4-carboxamide
Show/Hide
|
C20H32N4O3
|
1
|
| 1 |
Ki = 1.8 nM
|
|
|
|
CP0486722
|
N-[4-[2-[(5R)-7-chloro-5-methyl-1,2,4,5-tetrahydro-3-benzazepin-3-yl]ethyl]cyclohexyl]morpholine-4-carboxamide
Show/Hide
|
C24H36ClN3O2
|
1
|
| 1 |
Ki = 1.8 nM
|
|
|
|
CP0464341
|
N-[4-[4-(2,3-difluorophenyl)piperazin-1-yl]butyl]tricyclo[8.2.2.24,7]hexadeca-1(13),4,6,10(14),11,15-hexaene-5-carboxamide
Show/Hide
|
C31H35F2N3O
|
1
|
| 1 |
Ki = 1.9 nM
|
|
|
|
CP0380812
|
5-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy]pyrazolo[1,5-a]pyridine-2-carbonitrile
Show/Hide
|
C22H23Cl2N5O
|
1
|
| 1 |
Ki = 1.9 nM
|
|
|
|
CP0078330
|
7-[4-[4-(2,3-dichlorophenyl)-1,4-diazepan-1-yl]butoxy]-3,4-dihydro-1H-quinolin-2-one
Show/Hide
|
C24H29Cl2N3O2
|
1
|
| 1 |
Ki = 1.9 nM
|
|
|
|
CP0446908
|
8-hydroxy-5-[4-[4-[(2-oxo-3,4-dihydro-1H-quinolin-7-yl)oxy]butyl]-1,4-diazepan-1-yl]-1H-quinolin-2-one
Show/Hide
|
C27H32N4O4
|
1
|
| 1 |
Ki = 1.9 nM
|
|
|
|
CP0110281
|
Biphenyl-4-carboxylic acid {4-[4-(2,3-dichloro-phenyl)-piperazin-1-yl]-butyl}-amide
Show/Hide
|
C27H29Cl2N3O
|
1
|
| 1 |
Ki = 1.98 nM
|
|
|
|
CP0401622
|
ethyl 4-[2-[6-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-2-yl]ethyl]benzoate
Show/Hide
|
C27H37NO2
|
1
|
| 1 |
Ki = 1.995 nM
|
|
|
|
CP0460148
|
(NZ)-N-[1-[4-[2-[6-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-2-yl]ethyl]phenyl]ethylidene]hydroxylamine
Show/Hide
|
C26H36N2O
|
1
|
| 1 |
Ki = 1.995 nM
|
|
|
|
CP0383909
|
2-[4-methoxy-3-[5-[(2-phenylazepan-1-yl)methyl]-1H-pyrrol-2-yl]phenyl]sulfonyl-3,4-dihydro-1H-isoquinoline
Show/Hide
|
C33H37N3O3S
|
1
|
| 1 |
Ki = 1.995 nM
|
|
|
|
CP0384047
|
4-methoxy-N,N-dimethyl-3-[5-[(2-phenylazepan-1-yl)methyl]-1H-pyrrol-2-yl]benzenesulfonamide
Show/Hide
|
C26H33N3O3S
|
1
|
| 1 |
Ki = 1.995 nM
|
|
|
|
CP0377867
|
N-[4-[(3aS,9bS)-6-hydroxy-1,2,3a,4,5,9b-hexahydrobenzo[e]indol-3-yl]butyl]-4-phenylbenzamide
Show/Hide
|
C29H32N2O2
|
1
|
| 1 |
Ki = 1.995 nM
|
|
|
|
CP0381855
|
[2-[4-[[4-[3-(methylcarbamoyl)phenyl]benzoyl]amino]butyl]-3,4-dihydro-1H-isoquinolin-7-yl] trifluoromethanesulfonate
Show/Hide
|
C29H30F3N3O5S
|
1
|
| 1 |
Ki = 1.995 nM
|
|
|
|
CP0428823
|
[2-[4-[[(E)-3-(1H-indol-5-yl)prop-2-enoyl]amino]butyl]-3,4-dihydro-1H-isoquinolin-7-yl] trifluoromethanesulfonate
Show/Hide
|
C25H26F3N3O4S
|
1
|
| 1 |
Ki = 1.995 nM
|
|
|
|
CP0452809
|
[2-[4-[[4-[4-(5-methyl-1,3,4-oxadiazol-2-yl)phenyl]benzoyl]amino]butyl]-3,4-dihydro-1H-isoquinolin-7-yl] trifluoromethanesulfonate
Show/Hide
|
C30H29F3N4O5S
|
1
|
| 1 |
Ki = 1.995 nM
|
|
|
|
CP0740390
|
1H-Indole-2-carboxylic acid {4-[2-(7-cyano-3,4-dihydro-1H-isoquinolin-2-yl)-ethyl]-cyclohexyl}-amide
Show/Hide
|
C27H31ClN4O
|
1
|
| 1 |
Ki = 1.995 nM
|
|
|
|
CP0092640
|
4-butyl-N-(3-methyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-yl)benzenesulfonamide
Show/Hide
|
C21H28N2O2S
|
1
|
| 1 |
Ki = 1.995 nM
|
|
|
|
CP0377825
|
(E)-3-(3,5-difluorophenyl)-N-[4-[2-(7-methylsulfonyl-1,2,4,5-tetrahydro-3-benzazepin-3-yl)ethyl]cyclohexyl]prop-2-enamide;hydrochloride
Show/Hide
|
C28H35ClF2N2O3S
|
1
|
| 1 |
Ki = 1.995 nM
|
|
|
|
CP0424943
|
[3-[2-[4-[[(E)-3-(3-methoxyphenyl)prop-2-enoyl]amino]cyclohexyl]ethyl]-1,2,4,5-tetrahydro-3-benzazepin-7-yl] methanesulfonate;hydrochloride
Show/Hide
|
C29H39ClN2O5S
|
1
|
| 1 |
Ki = 1.995 nM
|
|
|
|
CP0452985
|
CHEMBL2368624
Show/Hide
|
C29H36ClN3O3S
|
1
|
| 1 |
Ki = 1.995 nM
|
|
|
|
CP0453063
|
[3-[2-[4-(quinoline-5-carbonylamino)cyclohexyl]ethyl]-1,2,4,5-tetrahydro-3-benzazepin-7-yl] methanesulfonate;hydrochloride
Show/Hide
|
C29H36ClN3O4S
|
1
|
| 1 |
Ki = 1.995 nM
|
|
|
|
CP0460719
|
CHEMBL3084601
Show/Hide
|
C30H37ClN4O4S
|
1
|
| 1 |
Ki = 1.995 nM
|
|
|
|
CP0461480
|
CHEMBL3084626
Show/Hide
|
C30H38ClN3O5S
|
1
|
| 1 |
Ki = 1.995 nM
|
|
|
|
CP0540318
|
CHEMBL2368617
Show/Hide
|
C29H36ClN3O3S
|
1
|
| 1 |
Ki = 1.995 nM
|
|
|
|
CP0372582
|
3-[2-[[5-(3,4-difluorophenyl)-4-methyl-1,2,4-triazol-3-yl]sulfanyl]ethyl]-7-(2,5-dimethylpyrazol-3-yl)-1,2,4,5-tetrahydro-3-benzazepine
Show/Hide
|
C26H28F2N6S
|
1
|
| 1 |
Ki = 1.995 nM
|
|
|
|
CP0372589
|
3-[3-[3-[(5-cyclopentyl-4-methyl-1,2,4-triazol-3-yl)sulfanyl]propyl]-1,2,4,5-tetrahydro-3-benzazepin-7-yl]-5-methyl-1,2-oxazole
Show/Hide
|
C25H33N5OS
|
1
|
| 1 |
Ki = 1.995 nM
|
|
|
|
CP0405809
|
5-methyl-2-[3-[3-[[4-methyl-5-(2-methylquinolin-5-yl)-1,2,4-triazol-3-yl]sulfanyl]propyl]-1,2,4,5-tetrahydro-3-benzazepin-7-yl]-1,3-oxazole
Show/Hide
|
C30H32N6OS
|
1
|
| 1 |
Ki = 1.995 nM
|
|
|
|
CP0427196
|
7-(5-methyl-3-isoxazolyl)-3-(3-{[4-methyl-5-(2-methyl-5-quinolinyl)-4H-1,2,4-triazol-3-yl]thio}propyl)-2,3,4,5-tetrahydro-1H-3-benzazepine
Show/Hide
|
C30H32N6OS
|
1
|
| 1 |
Ki = 1.995 nM
|
|
|
|
CP0405510
|
1-ethyl-2-[5-(5-ethylsulfonyl-2-methoxyphenyl)-1H-pyrrol-2-yl]azepane
Show/Hide
|
C21H30N2O3S
|
1
|
| 1 |
Ki = 1.995 nM
|
|
|
|
CP0501965
|
1-ethyl-2-[5-(5-ethylsulfonyl-2-methoxyphenyl)-1H-pyrrol-2-yl]piperidine
Show/Hide
|
C20H28N2O3S
|
1
|
| 1 |
Ki = 1.995 nM
|
|
|
|
CP0467571
|
4-(2-Benzylamino-ethoxy)-1,3-dihydro-benzoimidazole-2-thione
Show/Hide
|
C16H17N3OS
|
1
|
| 1 |
Ki = 2 nM
|
|
|
|
CP0375908
|
N-[4-[2-[4-(3-chlorophenyl)piperazin-1-yl]ethyl]cyclohexyl]thiophene-2-carboxamide
Show/Hide
|
C23H30ClN3OS
|
1
|
| 1 |
Ki = 2 nM
|
|
|
|
CP0878297
|
Cyclohexanecarboxylic acid {4-[2-(4-phenyl-piperazin-1-yl)-ethyl]-cyclohexyl}-amide
Show/Hide
|
C25H39N3O
|
1
|
| 1 |
Ki = 2 nM
|
|
|
|
CP0394874
|
4-[3-(1-butyltriazol-4-yl)propoxy]-3-methoxy-N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]benzamide
Show/Hide
|
C32H46N6O4
|
1
|
| 1 |
Ki = 2 nM
|
|
|
|
CP0440817
|
4-[3-[1-[8-[4-[3-[4-[4-[2,3-dihydro-1H-inden-2-yl(propyl)amino]butylcarbamoyl]-2-methoxyphenoxy]propyl]triazol-1-yl]octyl]triazol-4-yl]propoxy]-3-methoxy-N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]benzamide
Show/Hide
|
C65H91N11O7
|
1
|
| 1 |
Ki = 2 nM
|
|
|
|
CP0380808
|
6-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy]pyrazolo[1,5-a]pyridine-3-carbaldehyde
Show/Hide
|
C22H24Cl2N4O2
|
1
|
| 1 |
Ki = 2 nM
|
|
|
|
CP0388832
|
1-(3,4-difluorophenyl)imino-3-[4-[2,3-dihydro-1H-inden-2-yl(propyl)amino]butyl]urea
Show/Hide
|
C23H28F2N4O
|
1
|
| 1 |
Ki = 2 nM
|
|
|
|
CP0095896
|
2-cyclohexyl-N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]acetamide
Show/Hide
|
C23H37N3O2
|
1
|
| 1 |
Ki = 2 nM
|
|
|
|
CP0388497
|
ethyl N-[4-[2-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]ethyl]cyclohexyl]carbamate
Show/Hide
|
C22H32N4O2S
|
1
|
| 1 |
Ki = 2 nM
|
|
|
|
CP0472405
|
5-hydroxy-8-[4-[4-[(2-oxo-3,4-dihydro-1H-quinolin-7-yl)oxy]butyl]-1,4-diazepan-1-yl]-4H-1,4-benzoxazin-3-one
Show/Hide
|
C26H32N4O5
|
1
|
| 1 |
Ki = 2 nM
|
|
|
|
CP0380640
|
(2R,3S)-5-[3-[[4-methyl-5-(8-oxabicyclo[3.2.1]octan-3-yl)-1,2,4-triazol-3-yl]sulfanyl]propyl]-2-[4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptane
Show/Hide
|
C26H33F3N4OS
|
1
|
| 1 |
Ki = 2.089 nM
|
|
|
|
CP0458937
|
(R)-1-(bis(4-fluorophenyl)methyl)-4-(3-(3-(3,4-dimethoxyphenyl)-4,5-dihydroisoxazol-5-yl)propyl)piperazine
Show/Hide
|
C31H35F2N3O3
|
1
|
| 1 |
Ki = 2.1 nM
|
|
|
|
CP0525899
|
(R)-1-(3-(3-(3,4-dimethoxyphenyl)-4,5-dihydroisoxazol-5-yl)propyl)-4-(2-ethoxyphenyl)piperazine
Show/Hide
|
C26H35N3O4
|
1
|
| 1 |
Ki = 2.1 nM
|
|
|
|
CP0380813
|
ethyl 5-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy]pyrazolo[1,5-a]pyridine-2-carboxylate
Show/Hide
|
C24H28Cl2N4O3
|
1
|
| 1 |
Ki = 2.1 nM
|
|
|
|
CP0375102
|
(E)-N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]-3-[4-(trifluoromethyl)phenyl]prop-2-enamide
Show/Hide
|
C25H30F3N3O2
|
1
|
| 1 |
Ki = 2.14 nM
|
|
|
|
CP0406354
|
4-[3-(1-butyltriazol-4-yl)propoxy]-N-[4-[[(3S)-6-ethynyl-3,4-dihydro-2H-pyran-3-yl]-propylamino]butyl]-3-methoxybenzamide
Show/Hide
|
C31H45N5O4
|
1
|
| 1 |
Ki = 2.2 nM
|
|
|
|
CP0413700
|
5-[4-[2-[4-(2,3-dichlorophenyl)piperazin-1-yl]ethyl]triazol-1-yl]pyrazolo[1,5-a]pyridine
Show/Hide
|
C21H21Cl2N7
|
1
|
| 1 |
Ki = 2.2 nM
|
|
|
|
CP0412994
|
4-[4-(2,3-dichlorophenyl)piperazin-1-yl]-N-[3-[(Z)-hydroxyiminomethyl]pyrazolo[1,5-a]pyridin-5-yl]butanamide
Show/Hide
|
C22H24Cl2N6O2
|
1
|
| 1 |
Ki = 2.2 nM
|
|
|
|
CP0380806
|
6-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy]pyrazolo[1,5-a]pyridine
Show/Hide
|
C21H24Cl2N4O
|
1
|
| 1 |
Ki = 2.3 nM
|
|
|
|
CP0463820
|
N-[4-[2-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]ethyl]cyclohexyl]furan-2-carboxamide
Show/Hide
|
C24H30N4O2S
|
1
|
| 1 |
Ki = 2.3 nM
|
|
|
|
CP0042927
|
7-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy}-3,4-dihydroquinolin-2(1H)-one
Show/Hide
|
C23H27Cl2N3O2
|
5
|
| 1 |
Ki = 2.3 nM
|
|
|
| 2 |
Ki = 2.9 nM
|
|
|
| 3 |
Ki = 3 nM
|
|
|
| 4 |
Ki = 3.981 nM
|
|
|
| 5 |
Ki = 4.467 nM
|
|
|
|
CP0386863
|
(NE)-N-[[6-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butoxy]pyrazolo[1,5-a]pyridin-3-yl]methylidene]hydroxylamine
Show/Hide
|
C23H29N5O3
|
1
|
| 1 |
Ki = 2.3 nM
|
|
|
|
CP0405820
|
N-(3-cyanopyrazolo[1,5-a]pyridin-5-yl)-4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butanamide
Show/Hide
|
C22H22Cl2N6O
|
1
|
| 1 |
Ki = 2.3 nM
|
|
|
|
CP0408435
|
5-[4-[4-(8-hydroxy-2-oxo-1H-quinolin-5-yl)piperazin-1-yl]butoxy]pyrazolo[1,5-a]pyridine-3-carbaldehyde
Show/Hide
|
C25H27N5O4
|
1
|
| 1 |
Ki = 2.3 nM
|
|
|
|
CP0171885
|
1-benzyl-N-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl]-5-propyltriazole-4-carboxamide
Show/Hide
|
C27H34Cl2N6O
|
1
|
| 1 |
Ki = 2.399 nM
|
|
|
|
CP0428506
|
(R)-2-(Benzylamino-methyl)-chroman-7-ol; oxalic acid
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C17H19NO2
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1
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| 1 |
Ki = 2.4 nM
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CP0125802
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(R)-2-(Benzylamino-methyl)-3,4,7,9-tetrahydro-2H-pyrano[2,3-e]indol-8-one
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C19H20N2O2
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1
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| 1 |
Ki = 2.4 nM
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CP0440449
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5-Iodo-thiophene-2-carboxylic acid {4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-butyl}-amide
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C20H26IN3O2S
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1
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| 1 |
Ki = 2.4 nM
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CP0409215
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(E)-N-[4-[4-[(4-chlorophenyl)-phenylmethyl]piperazin-1-yl]butyl]-3-phenylprop-2-enamide
Show/Hide
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C30H34ClN3O
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1
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| 1 |
Ki = 2.4 nM
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CP0497217
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N-[4-[2-[4-(3-methylphenyl)piperazin-1-yl]ethyl]cyclohexyl]thiophene-2-carboxamide
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C24H33N3OS
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1
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| 1 |
Ki = 2.4 nM
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CP0408616
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N-[4-[4-[2-tert-butyl-6-(trifluoromethyl)pyrimidin-4-yl]piperazin-1-yl]butyl]-1-benzothiophene-2-carboxamide
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C26H32F3N5OS
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1
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| 1 |
Ki = 2.4 nM
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CP0918409
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4-Benzoyl-N-{4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-butyl}-benzamide oxalic acid
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C31H35N3O7
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1
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| 1 |
Ki = 2.5 nM
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CP0423258
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N-[4-[2-(4-phenylpiperazin-1-yl)ethyl]cyclohexyl]acetamide
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C20H31N3O
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1
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| 1 |
Ki = 2.5 nM
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CP0505352
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N-[4-[4-(2,5-dimethylphenyl)piperazin-1-yl]butyl]-1-benzothiophene-2-carboxamide
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C25H31N3OS
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1
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| 1 |
Ki = 2.5 nM
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CP0465405
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(1S)-N-ethyl-N-[[5-(5-ethylsulfonyl-2-methoxyphenyl)-1H-pyrrol-2-yl]methyl]-1-phenylethanamine
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C24H30N2O3S
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1
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| 1 |
Ki = 2.512 nM
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CP0492162
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N-[(3-chlorophenyl)methyl]-N-[[5-(5-ethylsulfonyl-2-methoxyphenyl)-1H-pyrrol-2-yl]methyl]ethanamine
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C23H27ClN2O3S
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1
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| 1 |
Ki = 2.512 nM
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CP0504683
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(3aR,9bS)-2-benzyl-3,3a,4,9b-tetrahydro-1H-chromeno[3,4-c]pyrrole-8-carbonitrile
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C19H18N2O
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1
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| 1 |
Ki = 2.512 nM
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CP0378741
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[2-[4-[[(E)-3-(2-oxo-1H-quinolin-6-yl)prop-2-enoyl]amino]butyl]-3,4-dihydro-1H-isoquinolin-7-yl] trifluoromethanesulfonate
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C26H26F3N3O5S
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1
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| 1 |
Ki = 2.512 nM
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CP0448111
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[2-[4-[[4-[4-(methylcarbamoyl)phenyl]benzoyl]amino]butyl]-3,4-dihydro-1H-isoquinolin-7-yl] trifluoromethanesulfonate
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C29H30F3N3O5S
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1
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| 1 |
Ki = 2.512 nM
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CP0454421
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[2-[4-[[4-[4-(2-oxopyrrolidin-1-yl)phenyl]benzoyl]amino]butyl]-3,4-dihydro-1H-isoquinolin-7-yl] trifluoromethanesulfonate
Show/Hide
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C31H32F3N3O5S
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1
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| 1 |
Ki = 2.512 nM
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CP0494813
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[2-[4-[[4-(4-acetylphenyl)benzoyl]amino]butyl]-3,4-dihydro-1H-isoquinolin-7-yl] trifluoromethanesulfonate
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C29H29F3N2O5S
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1
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| 1 |
Ki = 2.512 nM
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CP0645794
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4'-chloro-biphenyl-4-sulfonic acid (8-chloro-3-methyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-yl)-amide
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C23H22Cl2N2O2S
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1
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| 1 |
Ki = 2.512 nM
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CP0438340
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CHEMBL3084624
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C30H37ClN2O4S
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1
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| 1 |
Ki = 2.512 nM
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CP0449102
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CHEMBL3084613
Show/Hide
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C29H37ClN4O5S
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1
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| 1 |
Ki = 2.512 nM
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CP0511594
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CHEMBL2368619
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C28H35ClF2N2O3S
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1
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| 1 |
Ki = 2.512 nM
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CP0404758
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5-methyl-3-[3-[3-[(4-methyl-5-pyridin-2-yl-1,2,4-triazol-3-yl)sulfanyl]propyl]-1,2,4,5-tetrahydro-3-benzazepin-7-yl]-1,2-oxazole
Show/Hide
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C25H28N6OS
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1
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| 1 |
Ki = 2.512 nM
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CP0465216
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3-[3-[3-[[5-(6-methoxypyridin-3-yl)-4-methyl-1,2,4-triazol-3-yl]sulfanyl]propyl]-1,2,4,5-tetrahydro-3-benzazepin-7-yl]-5-methyl-1,2-oxazole
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C26H30N6O2S
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1
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| 1 |
Ki = 2.512 nM
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CP0465251
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3-[3-[3-[[5-(2-chlorophenyl)-4-methyl-1,2,4-triazol-3-yl]sulfanyl]propyl]-1,2,4,5-tetrahydro-3-benzazepin-7-yl]-5-methyl-1,2-oxazole
Show/Hide
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C26H28ClN5OS
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1
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| 1 |
Ki = 2.512 nM
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CP0049020
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1-(3-chlorophenyl)-3-[2-(1,3-dihydroisoindol-2-yl)ethyl]imidazolidin-2-one
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C19H20ClN3O
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1
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| 1 |
Ki = 2.512 nM
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CP0089213
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1-(3-chlorophenyl)-3-[2-(4-methylpiperidin-1-yl)ethyl]imidazolidin-2-one
Show/Hide
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C17H24ClN3O
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1
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| 1 |
Ki = 2.512 nM
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CP0191644
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3-[3-[2-(1,3-dihydroisoindol-2-yl)ethyl]-2-oxoimidazolidin-1-yl]benzonitrile
Show/Hide
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C20H20N4O
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1
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| 1 |
Ki = 2.512 nM
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CP0315221
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1-[2-(1,3-dihydroisoindol-2-yl)ethyl]-3-[3-(trifluoromethyl)phenyl]imidazolidin-2-one
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C20H20F3N3O
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1
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| 1 |
Ki = 2.512 nM
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CP0057009
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1-[2-[(1R,10S)-11-azatricyclo[8.2.2.03,8]tetradeca-3,5,7-trien-11-yl]ethyl]-3-(3-chlorophenyl)imidazolidin-2-one
Show/Hide
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C24H28ClN3O
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1
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| 1 |
Ki = 2.512 nM
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CP0086649
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1-(3-chlorophenyl)-3-[2-(diethylamino)ethyl]imidazolidin-2-one
Show/Hide
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C15H22ClN3O
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1
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| 1 |
Ki = 2.512 nM
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CP0280650
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1-[2-[(1R,4S)-2-azabicyclo[2.2.1]heptan-2-yl]ethyl]-3-(3-chlorophenyl)imidazolidin-2-one
Show/Hide
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C17H22ClN3O
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1
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| 1 |
Ki = 2.512 nM
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CP0081044
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N-[4-[[5-(cyclopropylmethoxy)-1,2,3,4-tetrahydronaphthalen-2-yl]-propylamino]butyl]-4-phenylbenzamide
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C34H42N2O2
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1
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| 1 |
Ki = 2.512 nM
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CP0273072
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N-[4-[(5-hydroxy-1,2,3,4-tetrahydronaphthalen-2-yl)-methylamino]butyl]-4-phenylbenzamide
Show/Hide
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C28H32N2O2
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1
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| 1 |
Ki = 2.512 nM
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CP0042188
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5-[5-[3-(5-bromospiro[1,2-dihydroindene-3,3'-pyrrolidine]-1'-yl)propylsulfanyl]-4-methyl-1,2,4-triazol-3-yl]-4-methyl-1,3-oxazole
Show/Hide
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C22H26BrN5OS
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1
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| 1 |
Ki = 2.512 nM
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CP0899360
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1-{4-[3-(3,4-Dimethoxy-phenyl)-isoxazol-5-yl]-butyl}-4-(2-ethoxy-phenyl)-piperazine hydrochloride
Show/Hide
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C27H36ClN3O4
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1
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| 1 |
Ki = 2.6 nM
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CP0046703
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1-(2-{4-[5-chloro-1-(4-fluorophenyl)-1H-indol-3-yl]piperidin-1-yl}ethyl)imidazolidin-2-one
Show/Hide
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C24H26ClFN4O
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1
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| 1 |
Ki = 2.6 nM
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CP0462407
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4-[4-methyl-5-[3-[(2R,3S)-2-[4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptan-5-yl]propylsulfanyl]-1,2,4-triazol-3-yl]piperidine-1-carboxamide
Show/Hide
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C25H33F3N6OS
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1
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| 1 |
Ki = 2.63 nM
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CP0460996
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N-[4-[4-(13-chloro-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-ylidene)piperidin-1-yl]butyl]-1-benzothiophene-2-carboxamide
Show/Hide
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C32H32ClN3OS
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1
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| 1 |
Ki = 2.7 nM
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CP0258018
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4-(2-Benzylamino-ethoxy)-1,3-dihydro-indol-2-one
Show/Hide
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C17H18N2O2
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1
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| 1 |
Ki = 2.8 nM
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CP0431302
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1-(3,4-difluorophenyl)imino-3-[2-[2,3-dihydro-1H-inden-2-yl(propyl)amino]ethyl]urea
Show/Hide
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C21H24F2N4O
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1
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| 1 |
Ki = 2.8 nM
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CP0097278
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N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]pyrazolo[1,5-a]pyridine-5-carboxamide
Show/Hide
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C23H29N5O2
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1
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| 1 |
Ki = 2.818 nM
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CP0454990
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N-[4-[4-[(4-chlorophenyl)-phenylmethyl]piperazin-1-yl]butyl]naphthalene-2-carboxamide
Show/Hide
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C32H34ClN3O
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1
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| 1 |
Ki = 2.82 nM
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CP0761608
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Biphenyl-4-carboxylic acid {4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-butyl}-amide oxalic acid
Show/Hide
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C30H35N3O6
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1
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| 1 |
Ki = 2.85 nM
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CP0405816
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5-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butoxy]pyrazolo[1,5-a]pyridine-3-carbonitrile
Show/Hide
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C23H27N5O2
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1
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| 1 |
Ki = 2.9 nM
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CP0403854
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9-Oxo-9H-fluorene-4-carboxylic acid {4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-butyl}-amide
Show/Hide
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C29H31N3O3
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1
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| 1 |
Ki = 2.96 nM
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CP0381816
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1-(4-fluorophenyl)imino-3-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]urea
Show/Hide
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C22H28FN5O2
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2
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| 1 |
Ki = 3 nM
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| 2 |
Ki = 3.1 nM
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CP0682498
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N-(4-(4-(2-chlorophenyl)piperazin-1-yl)butyl)-3,4-dimethoxybenzamide
Show/Hide
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C23H30ClN3O3
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1
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| 1 |
Ki = 3.09 nM
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CP0437040
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4-bromo-N-[4-[4-(2,5-dimethoxyphenyl)piperazin-1-yl]butyl]benzamide
Show/Hide
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C23H30BrN3O3
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1
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| 1 |
Ki = 3.162 nM
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CP0394421
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6-[2-(4-methoxyphenyl)ethyl]-N,N-dipropyl-1,2,3,4-tetrahydronaphthalen-2-amine
Show/Hide
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C25H35NO
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1
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| 1 |
Ki = 3.162 nM
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CP0528927
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1-[4-[2-[(6R)-6-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-2-yl]ethyl]phenyl]ethanone
Show/Hide
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C26H35NO
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1
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| 1 |
Ki = 3.162 nM
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CP0467013
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N-[[5-(5-ethylsulfonyl-2-methoxyphenyl)-1H-pyrrol-2-yl]methyl]-N-[(2-methylphenyl)methyl]ethanamine
Show/Hide
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C24H30N2O3S
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1
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| 1 |
Ki = 3.162 nM
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CP0404411
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N-[4-[2-[(3aS,9bR)-8-cyano-3,3a,4,9b-tetrahydro-1H-chromeno[3,4-c]pyrrol-2-yl]ethyl]phenyl]acetamide
Show/Hide
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C22H23N3O2
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1
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| 1 |
Ki = 3.162 nM
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CP0399806
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4-phenyl-N-[4-[propyl(4,5,6,7-tetrahydro-1H-indazol-5-yl)amino]butyl]benzamide
Show/Hide
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C27H34N4O
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1
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| 1 |
Ki = 3.162 nM
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CP0448505
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N-[4-[(4-methoxy-5,6,7,8-tetrahydroquinazolin-6-yl)-propylamino]butyl]-4-phenylbenzamide
Show/Hide
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C29H36N4O2
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1
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| 1 |
Ki = 3.162 nM
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CP0381877
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[2-[4-[[(E)-3-quinolin-6-ylprop-2-enoyl]amino]butyl]-3,4-dihydro-1H-isoquinolin-7-yl] trifluoromethanesulfonate
Show/Hide
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C26H26F3N3O4S
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1
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| 1 |
Ki = 3.162 nM
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CP0500898
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[2-[4-[[(E)-3-(3-methoxyphenyl)prop-2-enoyl]amino]butyl]-3,4-dihydro-1H-isoquinolin-7-yl] trifluoromethanesulfonate
Show/Hide
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C24H27F3N2O5S
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1
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| 1 |
Ki = 3.162 nM
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CP0711725
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N-{4-[2-(6-Cyano-3,4-dihydro-1H-isoquinolin-2-yl)-ethyl]-cyclohexyl}-3-phenyl-acrylamide
Show/Hide
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C27H32ClN3O
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1
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| 1 |
Ki = 3.162 nM
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CP0793460
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N-{4-[2-(6-Cyano-3,4-dihydro-1H-isoquinolin-2-yl)-ethyl]-cyclohexyl}-3-(4-fluoro-phenyl)-acrylamide
Show/Hide
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C27H31ClFN3O
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1
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| 1 |
Ki = 3.162 nM
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CP0801884
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(E)-N-[4-[2-(7-cyano-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]cyclohexyl]-3-(1H-indol-3-yl)prop-2-enamide;hydrochloride
Show/Hide
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C29H33ClN4O
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1
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| 1 |
Ki = 3.162 nM
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CP0384863
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CHEMBL87600
Show/Hide
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C29H35N3O2
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1
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| 1 |
Ki = 3.162 nM
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CP0430011
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(E)-3-(3-acetamidophenyl)-N-[4-[2-(7-cyano-1,2,4,5-tetrahydro-3-benzazepin-3-yl)ethyl]cyclohexyl]prop-2-enamide
Show/Hide
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C30H36N4O2
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1
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| 1 |
Ki = 3.162 nM
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CP0467619
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CHEMBL351300
Show/Hide
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C25H28BrFN2O
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1
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| 1 |
Ki = 3.162 nM
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CP0144743
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4'-chloro-biphenyl-4-sulfonic acid (8-isopropylamino-3-methyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-yl)-amide
Show/Hide
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C26H30ClN3O2S
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1
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| 1 |
Ki = 3.162 nM
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CP0377611
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CHEMBL3084629
Show/Hide
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C30H38ClN3O5S
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1
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| 1 |
Ki = 3.162 nM
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CP0453070
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[3-[2-[4-[[3-(4-methyl-1,3-oxazol-2-yl)benzoyl]amino]cyclohexyl]ethyl]-1,2,4,5-tetrahydro-3-benzazepin-7-yl] methanesulfonate;hydrochloride
Show/Hide
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C30H38ClN3O5S
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1
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| 1 |
Ki = 3.162 nM
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CP0460919
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CHEMBL3084596
Show/Hide
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C30H38ClN3O4S
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1
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| 1 |
Ki = 3.162 nM
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CP0470617
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CHEMBL3084605
Show/Hide
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C30H39ClN4O3S
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1
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| 1 |
Ki = 3.162 nM
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CP0479814
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8-fluoro-2-methyl-N-[4-[2-(7-methylsulfonyl-1,2,4,5-tetrahydro-3-benzazepin-3-yl)ethyl]cyclohexyl]quinoline-5-carboxamide;hydrochloride
Show/Hide
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C30H37ClFN3O3S
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1
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| 1 |
Ki = 3.162 nM
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CP0372584
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5-methyl-2-[3-[3-[(4-methyl-5-thiophen-2-yl-1,2,4-triazol-3-yl)sulfanyl]propyl]-1,2,4,5-tetrahydro-3-benzazepin-7-yl]-1,3-oxazole
Show/Hide
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C24H27N5OS2
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1
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| 1 |
Ki = 3.162 nM
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CP0372585
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3-[3-[3-[[5-(2-methoxyphenyl)-4-methyl-1,2,4-triazol-3-yl]sulfanyl]propyl]-1,2,4,5-tetrahydro-3-benzazepin-7-yl]-5-methyl-1,2-oxazole
Show/Hide
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C27H31N5O2S
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1
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| 1 |
Ki = 3.162 nM
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CP0404759
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5-methyl-3-[3-[3-[[4-methyl-5-[4-(trifluoromethyl)phenyl]-1,2,4-triazol-3-yl]sulfanyl]propyl]-1,2,4,5-tetrahydro-3-benzazepin-7-yl]-1,2-oxazole
Show/Hide
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C27H28F3N5OS
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1
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| 1 |
Ki = 3.162 nM
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CP0295407
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1-[2-(4-propan-2-ylpiperazin-1-yl)ethyl]-3-[3-(trifluoromethoxy)phenyl]imidazolidin-2-one
Show/Hide
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C19H27F3N4O2
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1
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| 1 |
Ki = 3.162 nM
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CP0092522
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1-[2-(3-azabicyclo[3.2.2]nonan-3-yl)ethyl]-3-(3-chlorophenyl)imidazolidin-2-one
Show/Hide
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C19H26ClN3O
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1
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| 1 |
Ki = 3.162 nM
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CP0362592
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5-[5-[3-[(1R,5S)-1-(4-tert-butylphenyl)-3-azabicyclo[3.1.0]hexan-3-yl]propylsulfanyl]-4-methyl-1,2,4-triazol-3-yl]-4-methyl-1,3-oxazole
Show/Hide
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C25H33N5OS
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1
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| 1 |
Ki = 3.162 nM
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CP0105802
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(2R,5S)-5-[2-fluoro-4-(trifluoromethyl)phenyl]-N-[3-[[4-methyl-5-(4-methyl-1,3-oxazol-5-yl)-1,2,4-triazol-3-yl]sulfanyl]propyl]bicyclo[3.1.0]hexan-2-amine
Show/Hide
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C23H25F4N5OS
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1
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| 1 |
Ki = 3.162 nM
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CP0373344
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N-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl]-4-(2-phenylethynyl)benzamide
Show/Hide
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C29H29Cl2N3O
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1
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| 1 |
Ki = 3.2 nM
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CP0404456
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N-[4-[2-[4-(2-methylphenyl)piperazin-1-yl]ethyl]cyclohexyl]thiophene-2-carboxamide
Show/Hide
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C24H33N3OS
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1
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| 1 |
Ki = 3.2 nM
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CP0378975
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N-[4-[[(1R)-4-ethynylcyclohex-3-en-1-yl]-propylamino]butyl]pyrazolo[1,5-a]pyridine-2-carboxamide
Show/Hide
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C23H30N4O
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1
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| 1 |
Ki = 3.2 nM
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CP0407988
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(NE)-N-[[5-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butoxy]pyrazolo[1,5-a]pyridin-2-yl]methylidene]hydroxylamine
Show/Hide
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C23H29N5O3
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1
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| 1 |
Ki = 3.2 nM
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CP0393916
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4-[3-(1-butyltriazol-4-yl)propoxy]-N-[4-[4-(8-hydroxy-2-oxo-1H-quinolin-5-yl)-1,4-diazepan-1-yl]butyl]-3-methoxybenzamide
Show/Hide
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C35H47N7O5
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1
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| 1 |
Ki = 3.2 nM
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CP0047409
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2-[4-[3-[2-(trifluoromethyl)-10-phenothiazinyl]propyl]-1-piperazinyl]ethanol;hydrochloride
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C22H26F3N3OS
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1
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| 1 |
Ki = 3.21 nM
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CP0862893
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4-Oxo-4H-chromene-3-carboxylic acid {4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-butyl}-amide oxalic acid
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C27H31N3O8
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1
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| 1 |
Ki = 3.3 nM
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CP0486724
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(1S,2S,6R,7R)-4-[4-[2-[(5R)-7-chloro-5-methyl-1,2,4,5-tetrahydro-3-benzazepin-3-yl]ethyl]cyclohexyl]-4-azatricyclo[5.2.1.02,6]decane-3,5-dione
Show/Hide
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C28H37ClN2O2
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1
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| 1 |
Ki = 3.3 nM
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CP0498245
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N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]-4-phenylcyclohexane-1-carboxamide
Show/Hide
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C28H39N3O2
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1
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| 1 |
Ki = 3.4 nM
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CP0458293
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8-hydroxy-5-[4-(4-pyrazolo[1,5-a]pyridin-5-yloxybutyl)-1,4-diazepan-1-yl]-1H-quinolin-2-one
Show/Hide
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C25H29N5O3
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1
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| 1 |
Ki = 3.4 nM
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CP0171883
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1-[(2-bromophenyl)methyl]-N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]-5-propyltriazole-4-carboxamide
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C28H37BrN6O2
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1
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| 1 |
Ki = 3.467 nM
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CP0838145
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5-bromo-N-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)butyl)benzofuran-2-carboxamide
Show/Hide
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C23H24BrCl2N3O2
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1
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| 1 |
Ki = 3.467 nM
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CP0233332
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CAS_18016-80-3
Show/Hide
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C20H26N4O
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1
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| 1 |
Ki = 3.467 nM
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CP0077311
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1-(3-(4-(5-chloro-2-oxo-2,3-dihydrobenzo[d]imidazol-1-yl)piperidin-1-yl)propyl)-1H-benzo[d]imidazol-2(3H)-one
Show/Hide
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C22H24ClN5O2
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1
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| 1 |
Ki = 3.5 nM
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CP0431087
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N-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]-5-[2-[2-[2-[2-[3-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propylcarbamoyl]pyrazolo[1,5-a]pyridin-5-yl]oxyethoxy]ethoxy]ethoxy]ethoxy]pyrazolo[1,5-a]pyridine-3-carboxamide
Show/Hide
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C52H68N10O9
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1
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| 1 |
Ki = 3.5 nM
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CP0380807
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2-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy]pyrazolo[1,5-a]pyridine
Show/Hide
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C21H24Cl2N4O
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1
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| 1 |
Ki = 3.5 nM
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CP0380082
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Haldol
Show/Hide
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C31H41ClFNO3
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1
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| 1 |
Ki = 3.5 nM
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CP0534532
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N-[4-[4-(2-oxo-1,3-dihydrobenzimidazol-4-yl)piperazin-1-yl]butyl]naphthalene-2-carboxamide
Show/Hide
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C26H29N5O2
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1
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| 1 |
Ki = 3.5 nM
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CP0401110
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5-hydroxy-8-[2-[2-[3-methoxy-4-(3-phenylpropoxy)phenyl]ethylamino]ethyl]-4H-1,4-benzoxazin-3-one
Show/Hide
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C28H32N2O5
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1
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| 1 |
Ki = 3.5 nM
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CP0445345
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N-[4-[4-[(2-methoxyphenyl)-phenylmethyl]piperazin-1-yl]butyl]-1-benzothiophene-2-carboxamide
Show/Hide
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C31H35N3O2S
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1
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| 1 |
Ki = 3.6 nM
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CP0397948
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(E)-N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]-3-[4-[(E)-3-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butylamino]-3-oxoprop-1-enyl]phenyl]prop-2-enamide
Show/Hide
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C42H56N6O4
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1
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| 1 |
Ki = 3.6 nM
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CP0433429
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N-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl]tricyclo[8.2.2.24,7]hexadeca-1(13),4,6,10(14),11,15-hexaene-5-carboxamide
Show/Hide
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C31H35Cl2N3O
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1
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| 1 |
Ki = 3.6 nM
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CP0036333
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(S)-3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide
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C15H20Cl2N2O3
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2
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| 1 |
Ki = 3.7 nM
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| 2 |
Ki = 15 nM
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CP0389291
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5-hydroxy-8-(4-propyl-1,4-diazepan-1-yl)-4H-1,4-benzoxazin-3-one
Show/Hide
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C16H23N3O3
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1
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| 1 |
Ki = 3.7 nM
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CP0452811
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11-methoxy-7,14-dimethyl-6,7,8,9,14,15-hexahydro-5Hindolo[3,2-f][3]benzazecine
Show/Hide
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C22H26N2O
|
1
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| 1 |
Ki = 3.78 nM
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CP0446909
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8-hydroxy-5-[4-(4-pyrazolo[1,5-a]pyridin-5-yloxybutyl)piperazin-1-yl]-1H-quinolin-2-one
Show/Hide
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C24H27N5O3
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1
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| 1 |
Ki = 3.8 nM
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CP0918857
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1-(2-Ethoxy-phenyl)-4-[4-(3-thiophen-2-yl-isoxazol-5-yl)-butyl]-piperazine hydrochloride
Show/Hide
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C23H30ClN3O2S
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1
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| 1 |
Ki = 3.9 nM
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CP0184839
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4-Iodo-N-{4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-butyl}-benzamide
Show/Hide
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C22H28IN3O2
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1
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| 1 |
Ki = 3.9 nM
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CP0364135
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ethyl N-[3-[4-[4-(naphthalene-2-carbonylamino)butyl]piperazin-1-yl]phenyl]carbamate
Show/Hide
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C28H34N4O3
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1
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| 1 |
Ki = 3.9 nM
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CP0383487
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(2R)-6-[2-(4-chlorophenyl)ethyl]-N,N-dipropyl-1,2,3,4-tetrahydronaphthalen-2-amine
Show/Hide
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C24H32ClN
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1
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| 1 |
Ki = 3.981 nM
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CP0460722
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1-[4-[2-[6-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-2-yl]ethyl]phenyl]ethanone
Show/Hide
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C26H35NO
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1
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| 1 |
Ki = 3.981 nM
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CP0465315
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6-(2-phenylethyl)-N,N-dipropyl-1,2,3,4-tetrahydronaphthalen-2-amine
Show/Hide
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C24H33N
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1
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| 1 |
Ki = 3.981 nM
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CP0448632
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4-methoxy-N-methyl-N-phenyl-3-[5-[[(2R)-2-phenylazepan-1-yl]methyl]-1H-pyrrol-2-yl]benzenesulfonamide
Show/Hide
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C31H35N3O3S
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1
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| 1 |
Ki = 3.981 nM
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CP0501148
|
(2S)-1-[[5-(5-ethylsulfonyl-2-methoxyphenyl)-1H-pyrrol-2-yl]methyl]-2-phenylazepane
Show/Hide
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C26H32N2O3S
|
1
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| 1 |
Ki = 3.981 nM
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CP0510000
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1-[[5-(5-benzylsulfonyl-2-methoxyphenyl)-1H-pyrrol-2-yl]methyl]-2-phenylazepane
Show/Hide
|
C31H34N2O3S
|
1
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| 1 |
Ki = 3.981 nM
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CP0380166
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[2-[4-[[(E)-3-(4-acetylphenyl)prop-2-enoyl]amino]butyl]-3,4-dihydro-1H-isoquinolin-7-yl] trifluoromethanesulfonate
Show/Hide
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C25H27F3N2O5S
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1
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| 1 |
Ki = 3.981 nM
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CP0381818
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[2-[4-[[(E)-3-(4-methoxyphenyl)prop-2-enoyl]amino]butyl]-3,4-dihydro-1H-isoquinolin-7-yl] trifluoromethanesulfonate
Show/Hide
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C24H27F3N2O5S
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1
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| 1 |
Ki = 3.981 nM
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CP0381876
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[2-[4-[[(E)-3-quinolin-2-ylprop-2-enoyl]amino]butyl]-3,4-dihydro-1H-isoquinolin-7-yl] trifluoromethanesulfonate
Show/Hide
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C26H26F3N3O4S
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1
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| 1 |
Ki = 3.981 nM
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CP0448424
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[2-[4-[[(E)-3-quinolin-3-ylprop-2-enoyl]amino]butyl]-3,4-dihydro-1H-isoquinolin-7-yl] trifluoromethanesulfonate
Show/Hide
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C26H26F3N3O4S
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1
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| 1 |
Ki = 3.981 nM
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CP0502095
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[2-[4-[[(E)-3-(1H-indol-3-yl)prop-2-enoyl]amino]butyl]-3,4-dihydro-1H-isoquinolin-7-yl] trifluoromethanesulfonate
Show/Hide
|
C25H26F3N3O4S
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1
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| 1 |
Ki = 3.981 nM
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CP0504018
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[2-[4-[[(E)-3-[4-(dimethylamino)phenyl]prop-2-enoyl]amino]butyl]-3,4-dihydro-1H-isoquinolin-7-yl] trifluoromethanesulfonate
Show/Hide
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C25H30F3N3O4S
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1
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| 1 |
Ki = 3.981 nM
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CP0514197
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[2-[4-[[(E)-3-(3-acetylphenyl)prop-2-enoyl]amino]butyl]-3,4-dihydro-1H-isoquinolin-7-yl] trifluoromethanesulfonate
Show/Hide
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C25H27F3N2O5S
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1
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| 1 |
Ki = 3.981 nM
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CP0694718
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Trifluoro-methanesulfonic acid 2-[4-(3-1H-indol-3-yl-acryloylamino)-butyl]-1,2,3,4-tetrahydro-isoquinolin-7-yl ester
Show/Hide
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C25H27ClF3N3O4S
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1
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| 1 |
Ki = 3.981 nM
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CP0405384
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(E)-3-(3-acetamido-2-fluorophenyl)-N-[4-[2-(7-cyano-1,2,4,5-tetrahydro-3-benzazepin-3-yl)ethyl]cyclohexyl]prop-2-enamide
Show/Hide
|
C30H35FN4O2
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1
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| 1 |
Ki = 3.981 nM
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CP0506564
|
CHEMBL419487
Show/Hide
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C30H35N3O2
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1
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| 1 |
Ki = 3.981 nM
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CP0656165
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4'-chloro-biphenyl-4-sulfonic acid (8-isopropyl-3-methyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-yl)-amide
Show/Hide
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C26H29ClN2O2S
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1
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| 1 |
Ki = 3.981 nM
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CP0717380
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3'-chloro-4'-fluoro-biphenyl-4-sulfonic acid (3-methyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-yl)-amide
Show/Hide
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C23H22ClFN2O2S
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1
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| 1 |
Ki = 3.981 nM
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CP0377868
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3-(3-methyl-1,2-oxazol-5-yl)-N-[4-[2-(7-methylsulfonyl-1,2,4,5-tetrahydro-3-benzazepin-3-yl)ethyl]cyclohexyl]benzamide;hydrochloride
Show/Hide
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C30H38ClN3O4S
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1
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| 1 |
Ki = 3.981 nM
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CP0448457
|
CHEMBL3084599
Show/Hide
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C30H38ClN3O3S
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1
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| 1 |
Ki = 3.981 nM
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CP0916748
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N-{4-[2-(7-Methanesulfonyl-1,2,4,5-tetrahydro-benzo[d]azepin-3-yl)-ethyl]-cyclohexyl}-3-(5-methyl-[1,2,4]oxadiazol-3-yl)-benzamide hydrochloride
Show/Hide
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C29H37ClN4O4S
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1
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| 1 |
Ki = 3.981 nM
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CP0200768
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N-[4-[2-(6-cyano-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]cyclohexyl]quinoline-4-carboxamide
Show/Hide
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C28H30N4O
|
3
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| 1 |
Ki = 3.981 nM
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| 2 |
Ki = 10 nM
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| 3 |
Ki > 10000 nM
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CP0372579
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4-[4-methyl-5-[3-[7-(5-methyl-1,2-oxazol-3-yl)-1,2,4,5-tetrahydro-3-benzazepin-3-yl]propylsulfanyl]-1,2,4-triazol-3-yl]benzonitrile
Show/Hide
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C27H28N6OS
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1
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| 1 |
Ki = 3.981 nM
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CP0291324
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1-(2,3-dihydro-1,4-benzodioxin-5-yl)-4-[[5-(4-fluorophenyl)pyridin-3-yl]methyl]piperazine
Show/Hide
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C24H24FN3O2
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1
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| 1 |
Ki = 3.981 nM
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CP0427995
|
Amisulpride
Show/Hide
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C17H27N3O4S
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1
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| 1 |
Ki = 3.981 nM
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CP0367474
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3-[2-oxo-3-[2-(4-propan-2-ylpiperazin-1-yl)ethyl]imidazolidin-1-yl]benzonitrile
Show/Hide
|
C19H27N5O
|
1
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| 1 |
Ki = 3.981 nM
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CP0154055
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6-[4-[(4-phenylbenzoyl)amino]butyl-propylamino]-5,6,7,8-tetrahydronaphthalene-1-carboxamide
Show/Hide
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C31H37N3O2
|
1
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| 1 |
Ki = 3.981 nM
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CP0193930
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8-[3-[[4-methyl-5-(2-methylquinolin-5-yl)-1,2,4-triazol-3-yl]sulfanyl]propyl]-2-(trifluoromethyl)-6,7,9,10-tetrahydro-[1,3]oxazolo[5,4-i][3]benzazepine
Show/Hide
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C28H27F3N6OS
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1
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| 1 |
Ki = 3.981 nM
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CP0661519
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5-[5-({3-[(1R,5S/1S,5R)-1-(4-Bromophenyl)-3-azabicyclo[3.1.0]-hex-3-yl]propyl}thio)-4-methyl-4H-1,2,4-triazol-3-yl]-2-methylquinoline
Show/Hide
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C27H28BrN5S
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1
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| 1 |
Ki = 3.981 nM
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CP0039025
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4-(3-{[4-Methyl-5-(4-pyridazinyl)-4H-1,2,4-triazol-3-yl]thio}-propyl)-1-[4-(trifluoromethyl)phenyl]-4-azabicyclo[5.1.0]octane
Show/Hide
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C24H27F3N6S
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1
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| 1 |
Ki = 3.981 nM
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CP0297532
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4-methyl-5-[4-methyl-5-[3-[1-[4-(trifluoromethyl)phenyl]-4-azabicyclo[5.1.0]octan-4-yl]propylsulfanyl]-1,2,4-triazol-3-yl]-1,3-oxazole
Show/Hide
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C24H28F3N5OS
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1
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| 1 |
Ki = 3.981 nM
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CP0342373
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2,4-dimethyl-5-[4-methyl-5-[3-[1-[4-(trifluoromethyl)phenyl]-4-azabicyclo[5.1.0]octan-4-yl]propylsulfanyl]-1,2,4-triazol-3-yl]-1,3-thiazole
Show/Hide
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C25H30F3N5S2
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1
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| 1 |
Ki = 3.981 nM
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CP0051912
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(5S)-N,N-dipropyl-4,5,6,7-tetrahydropyrazolo[1,5-a]pyridin-5-amine
Show/Hide
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C13H23N3
|
4
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| 1 |
Ki = 4 nM
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| 2 |
Ki = 14 nM
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| 3 |
Ki = 31 nM
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| 4 |
Ki = 110 nM
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CP0466909
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N-[4-[2-[4-(2,3-dichlorophenyl)piperazin-1-yl]ethyl]cyclohexyl]cyclopentanecarboxamide
Show/Hide
|
C24H35Cl2N3O
|
1
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| 1 |
Ki = 4 nM
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CP0488819
|
N-[4-[4-(5-tricyclo[8.2.2.24,7]hexadeca-1(13),4,6,10(14),11,15-hexaenyl)piperazin-1-yl]butyl]tricyclo[8.2.2.24,7]hexadeca-1(13),4,6,10(14),11,15-hexaene-5-carboxamide
Show/Hide
|
C41H47N3O
|
1
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| 1 |
Ki = 4 nM
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CP0398327
|
1-methyl-4-[4-methyl-5-[3-[(2R,3S)-2-[4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptan-5-yl]propylsulfanyl]-1,2,4-triazol-3-yl]pyridin-2-one
Show/Hide
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C25H28F3N5OS
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1
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| 1 |
Ki = 4.074 nM
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CP0464792
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4-(2-Benzylamino-ethoxy)-1,3-dihydro-benzoimidazol-2-one
Show/Hide
|
C16H17N3O2
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1
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| 1 |
Ki = 4.1 nM
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CP0893905
|
N-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-3-(3-trifluoromethyl-phenyl)-acrylamide oxalic acid
Show/Hide
|
C27H32F3N3O6
|
1
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| 1 |
Ki = 4.1 nM
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CP0409085
|
((1S,2R)-5-Methoxy-1-methyl-1,2,3,4-tetrahydro-naphthalen-2-yl)-dipropyl-amine
Show/Hide
|
C18H29NO
|
2
|
| 1 |
Ki = 4.2 nM
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| 2 |
Ki = 12.59 nM
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CP0433258
|
(-)-(S)-N-((1-ethylpyrrolidin-2-yl)methyl)-2-hydroxy-3-iodo-6-methoxybenzamide
Show/Hide
|
C15H21IN2O3
|
1
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| 1 |
Ki = 4.2 nM
|
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CP0467070
|
N-[4-[2-[4-(2,3-dichlorophenyl)piperazin-1-yl]ethyl]cyclohexyl]-N-methylthiophene-2-carboxamide
Show/Hide
|
C24H31Cl2N3OS
|
1
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| 1 |
Ki = 4.2 nM
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CP0475763
|
4-[4-([2.2]Paracyclophan-4-yl)piperazin-1-yl]-1-([2.2]paracyclophan-4-yl)butan-1-one
Show/Hide
|
C41H45NO
|
1
|
| 1 |
Ki = 4.2 nM
|
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CP0183951
|
1-benzyl-N-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl]-5-methyltriazole-4-carboxamide
Show/Hide
|
C25H30Cl2N6O
|
1
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| 1 |
Ki = 4.266 nM
|
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CP0711087
|
5-cyano-N-(4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl)benzofuran-2-carboxamide
Show/Hide
|
C25H28N4O3
|
1
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| 1 |
Ki = 4.266 nM
|
|
|
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CP0439421
|
4-Fluoro-N-{4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-butyl}-benzamide
Show/Hide
|
C22H28FN3O2
|
1
|
| 1 |
Ki = 4.3 nM
|
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CP0372976
|
N-[4-[2-(4-pyridin-2-ylpiperazin-1-yl)ethyl]cyclohexyl]thiophene-2-carboxamide
Show/Hide
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C22H30N4OS
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1
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| 1 |
Ki = 4.3 nM
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CP0448643
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N-[4-[2-[4-(4-methylphenyl)piperazin-1-yl]ethyl]cyclohexyl]thiophene-2-carboxamide
Show/Hide
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C24H33N3OS
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1
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| 1 |
Ki = 4.3 nM
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CP0375613
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4-[3-(2-butyltriazol-4-yl)propoxy]-N-[4-[[(1R)-4-ethynylcyclohex-3-en-1-yl]-propylamino]butyl]-3-methoxybenzamide
Show/Hide
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C32H47N5O3
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1
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| 1 |
Ki = 4.3 nM
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CP0103545
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(-)-5-hydroxy-2-(dipropylamino)tetralin
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C16H25NO
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1
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| 1 |
Ki = 4.4 nM
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CP0398431
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4-phenyl-N-[4-[propyl-[4-(2-trimethylsilylethynyl)cyclohex-3-en-1-yl]amino]butyl]benzamide
Show/Hide
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C31H42N2OSi
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1
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| 1 |
Ki = 4.4 nM
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CP0413702
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5-[4-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl]triazol-1-yl]pyrazolo[1,5-a]pyridine-3-carbaldehyde
Show/Hide
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C24H25Cl2N7O
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1
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| 1 |
Ki = 4.4 nM
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CP0392475
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5-Iodo-benzo[b]thiophene-2-carboxylic acid {4-[4-(2,3-dichloro-phenyl)-piperazin-1-yl]-butyl}-amide
Show/Hide
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C23H24Cl2IN3OS
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1
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| 1 |
Ki = 4.5 nM
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CP0524090
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N-[4-[2-[4-(2,3-dichlorophenyl)piperazin-1-yl]ethyl]cyclohexyl]cyclohexanecarboxamide
Show/Hide
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C25H37Cl2N3O
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1
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| 1 |
Ki = 4.5 nM
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CP0134204
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(3Z)-3-(2-chloro-9H-thioxanthen-9-ylidene)-N,N-dimethylpropan-1-amine
Show/Hide
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C18H18ClNS
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1
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| 1 |
Ki = 4.56 nM
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CP0895111
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1-(2-Methoxy-phenyl)-4-[4-(3-thiophen-2-yl-isoxazol-5-yl)-butyl]-piperazine hydrochloride
Show/Hide
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C22H28ClN3O2S
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1
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| 1 |
Ki = 4.7 nM
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CP0380291
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N-[4-[2-[4-(2,3-dichlorophenyl)piperazin-1-yl]ethyl]cyclohexyl]benzamide
Show/Hide
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C25H31Cl2N3O
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1
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| 1 |
Ki = 4.7 nM
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CP0410073
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N-[4-[2-[4-(2,3-dichlorophenyl)piperazin-1-yl]ethyl]cyclohexyl]thiophene-3-carboxamide
Show/Hide
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C23H29Cl2N3OS
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1
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| 1 |
Ki = 4.7 nM
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CP0473734
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N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]-2,5-dimethylbenzamide
Show/Hide
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C24H33N3O2
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1
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| 1 |
Ki = 4.7 nM
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CP0095894
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N-[4-[4-(3-chlorophenyl)piperazin-1-yl]butyl]naphthalene-2-carboxamide
Show/Hide
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C25H28ClN3O
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1
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| 1 |
Ki = 4.7 nM
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CP0194254
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4-(1H-imidazol-1-yl)-N-(4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl)benzamide
Show/Hide
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C25H31N5O2
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1
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| 1 |
Ki = 4.79 nM
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CP0848297
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N-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-3-phenyl-propionamide oxalic acid
Show/Hide
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C26H35N3O6
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1
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| 1 |
Ki = 4.8 nM
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CP0404256
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N-[4-[2-[4-(2,3-dichlorophenyl)piperazin-1-yl]ethyl]cyclohexyl]cycloheptanecarboxamide
Show/Hide
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C26H39Cl2N3O
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1
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| 1 |
Ki = 4.8 nM
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CP0087394
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N-[2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl]-1-(4-nitrophenyl)triazole-4-carboxamide
Show/Hide
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C22H25N7O4
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1
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| 1 |
Ki = 4.9 nM
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CP0372550
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3-(2-ethoxyethoxy)-N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]benzamide
Show/Hide
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C26H37N3O4
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1
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| 1 |
Ki = 4.9 nM
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CP0376123
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1-[4-[2,3-dihydro-1H-inden-2-yl(propyl)amino]butyl]-3-(3,4,5-trifluorophenyl)iminourea
Show/Hide
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C23H27F3N4O
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1
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| 1 |
Ki = 4.9 nM
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CP0505181
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(3-{4-[1-((E)-4-{2-[4-(3-Dipropylamino-propoxy)-phenyl]-benzoimidazol-1-yl}-but-2-enyl)-1H-benzoimidazol-2-yl]-phenoxy}-propyl)-dipropyl-amine
Show/Hide
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C48H62N6O2
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1
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| 1 |
Ki = 5 nM
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CP0498652
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N-[4-[2-[4-(2-chlorophenyl)piperazin-1-yl]ethyl]cyclohexyl]cyclohexanecarboxamide
Show/Hide
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C25H38ClN3O
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1
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| 1 |
Ki = 5 nM
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CP0405801
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6-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butoxy]pyrazolo[1,5-a]pyridine
Show/Hide
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C22H28N4O2
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1
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| 1 |
Ki = 5 nM
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CP0461446
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(2R)-6-[2-(4-chlorophenyl)ethyl]-5-methoxy-N,N-dipropyl-1,2,3,4-tetrahydronaphthalen-2-amine
Show/Hide
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C25H34ClNO
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1
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| 1 |
Ki = 5.012 nM
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CP0436489
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N-ethyl-N-[[5-(5-ethylsulfonyl-2-methoxyphenyl)-1H-pyrrol-2-yl]methyl]-1,2,3,4-tetrahydronaphthalen-1-amine
Show/Hide
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C26H32N2O3S
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1
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| 1 |
Ki = 5.012 nM
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CP0430222
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1-[[5-(2-methoxy-5-propan-2-ylsulfonylphenyl)-1H-pyrrol-2-yl]methyl]-2-phenylazepane
Show/Hide
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C27H34N2O3S
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1
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| 1 |
Ki = 5.012 nM
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CP0454926
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[(3aS,9bS)-3-[4-[(4-phenylbenzoyl)amino]butyl]-1,2,3a,4,5,9b-hexahydrobenzo[e]indol-6-yl] methanesulfonate
Show/Hide
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C30H34N2O4S
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1
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| 1 |
Ki = 5.012 nM
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CP0394303
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[2-[4-[[(E)-3-phenylprop-2-enoyl]amino]butyl]-3,4-dihydro-1H-isoquinolin-7-yl] trifluoromethanesulfonate
Show/Hide
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C23H25F3N2O4S
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1
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| 1 |
Ki = 5.012 nM
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CP0448423
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[2-[4-[[(E)-3-naphthalen-2-ylprop-2-enoyl]amino]butyl]-3,4-dihydro-1H-isoquinolin-7-yl] trifluoromethanesulfonate
Show/Hide
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C27H27F3N2O4S
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1
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| 1 |
Ki = 5.012 nM
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CP0692382
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N-{4-[2-(6-Cyano-3,4-dihydro-1H-isoquinolin-2-yl)-ethyl]-cyclohexyl}-3-(3-methanesulfonyl-phenyl)-acrylamide
Show/Hide
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C28H34ClN3O3S
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1
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| 1 |
Ki = 5.012 nM
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CP0136853
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[2-[2-[4-[[(E)-3-(4-fluorophenyl)prop-2-enoyl]amino]cyclohexyl]ethyl]-1,3-dihydroisoindol-5-yl] methanesulfonate
Show/Hide
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C26H31FN2O4S
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1
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| 1 |
Ki = 5.012 nM
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CP0784130
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4'-chloro-biphenyl-4-sulfonic acid (8-bromo-3-methyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-yl)-amide
Show/Hide
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C23H22BrClN2O2S
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1
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| 1 |
Ki = 5.012 nM
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CP0426962
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7-(2,5-dimethylpyrazol-3-yl)-3-[2-[[4-methyl-5-(5-methylpyrazin-2-yl)-1,2,4-triazol-3-yl]sulfanyl]ethyl]-1,2,4,5-tetrahydro-3-benzazepine
Show/Hide
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C25H30N8S
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1
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| 1 |
Ki = 5.012 nM
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CP0465250
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3-[3-[3-[(5-tert-butyl-4-methyl-1,2,4-triazol-3-yl)sulfanyl]propyl]-1,2,4,5-tetrahydro-3-benzazepin-7-yl]-5-methyl-1,2-oxazole
Show/Hide
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C24H33N5OS
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1
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| 1 |
Ki = 5.012 nM
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CP0363923
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(racemic)5'-(5-Ethanesulfonyl-2-methoxy-phenyl)-1-ethyl-2,3,4,5-tetrahydro-1H,1'H-[2,2']bipyrrolyl
Show/Hide
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C19H26N2O3S
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1
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| 1 |
Ki = 5.012 nM
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CP0089214
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1-[3-(trifluoromethoxy)phenyl]-3-[2-[4-(trifluoromethyl)piperidin-1-yl]ethyl]imidazolidin-2-one
Show/Hide
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C18H21F6N3O2
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1
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| 1 |
Ki = 5.012 nM
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CP0104098
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1-[2-[(7,7-dimethyl-1-bicyclo[2.2.1]heptanyl)methyl-methylamino]ethyl]-3-(3-methoxyphenyl)imidazolidin-2-one
Show/Hide
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C23H35N3O2
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1
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| 1 |
Ki = 5.012 nM
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CP0233543
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5-[5-[3-(6-bromospiro[1,2-dihydroindene-3,3'-pyrrolidine]-1'-yl)propylsulfanyl]-4-methyl-1,2,4-triazol-3-yl]-4-methyl-1,3-oxazole
Show/Hide
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C22H26BrN5OS
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1
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| 1 |
Ki = 5.012 nM
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CP0434336
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(S)-1-(3-(3-(3,4-dimethoxyphenyl)-4,5-dihydroisoxazol-5-yl)propyl)-4-(2-ethoxyphenyl)piperazine
Show/Hide
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C26H35N3O4
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1
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| 1 |
Ki = 5.1 nM
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CP0942040
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1-{4-[3-(3,4-Dimethoxy-phenyl)-isoxazol-5-yl]-butyl}-4-(2-methoxy-phenyl)-piperazine hydrochloride
Show/Hide
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C26H34ClN3O4
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1
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| 1 |
Ki = 5.2 nM
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CP0415599
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N-[4-[2-[4-(3,4-dimethylphenyl)piperazin-1-yl]ethyl]cyclohexyl]cyclohexanecarboxamide
Show/Hide
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C27H43N3O
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1
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| 1 |
Ki = 5.2 nM
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CP0290176
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(S)-7-Dipropylamino-5,6,7,8-tetrahydro-indolizine-3-carbaldehyde
Show/Hide
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C15H24N2O
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3
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| 1 |
Ki = 5.248 nM
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| 2 |
Ki = 5.3 nM
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| 3 |
Ki = 150 nM
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CP0156986
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4-(4-Benzyl-piperazin-1-yl)-1,3-dihydro-indol-2-one
Show/Hide
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C19H21N3O
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1
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| 1 |
Ki = 5.4 nM
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CP0393063
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N-[5-[4-(2,3-dichlorophenyl)piperazin-1-yl]pentyl]-3-ethynylbenzamide
Show/Hide
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C24H27Cl2N3O
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1
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| 1 |
Ki = 5.6 nM
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CP0405814
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4-[4-(2,3-dichlorophenyl)piperazin-1-yl]-N-pyrazolo[1,5-a]pyridin-5-ylbutanamide
Show/Hide
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C21H23Cl2N5O
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1
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| 1 |
Ki = 5.6 nM
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CP0253779
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5-Iodo-benzofuran-2-carboxylic acid {4-[4-(2,3-dichloro-phenyl)-piperazin-1-yl]-butyl}-amide
Show/Hide
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C23H24Cl2IN3O2
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1
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| 1 |
Ki = 5.7 nM
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CP0418145
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2-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy]pyrazolo[1,5-a]pyridine-3-carbaldehyde
Show/Hide
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C22H24Cl2N4O2
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1
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| 1 |
Ki = 5.9 nM
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CP0489219
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[4-(4-chlorophenyl)-1-[4-(4-fluorophenyl)-4-oxobutyl]piperidin-4-yl] 3-[1-[10-[4-[3-[4-(4-chlorophenyl)-1-[4-(4-fluorophenyl)-4-oxobutyl]piperidin-4-yl]oxy-3-oxopropyl]triazol-1-yl]decyl]triazol-4-yl]propanoate
Show/Hide
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C62H74Cl2F2N8O6
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1
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| 1 |
Ki = 5.9 nM
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CP0408430
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5-hydroxy-8-(4-propylpiperazin-1-yl)-4H-1,4-benzoxazin-3-one
Show/Hide
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C15H21N3O3
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1
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| 1 |
Ki = 5.9 nM
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CP0869072
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1-(2-Methoxy-phenyl)-4-{4-[3-(3-nitro-phenyl)-isoxazol-5-yl]-butyl}-piperazine hydrochloride
Show/Hide
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C24H29ClN4O4
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1
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| 1 |
Ki = 6 nM
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CP0380220
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N-[4-[2-[4-(3-chlorophenyl)piperazin-1-yl]ethyl]cyclohexyl]cyclohexanecarboxamide
Show/Hide
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C25H38ClN3O
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1
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| 1 |
Ki = 6 nM
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CP0380804
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5-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy]pyrazolo[1,5-a]pyridine-2-carbaldehyde
Show/Hide
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C22H24Cl2N4O2
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1
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| 1 |
Ki = 6 nM
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CP0471200
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N-[4-[4-(13-chloro-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-ylidene)piperidin-1-yl]butyl]naphthalene-2-carboxamide
Show/Hide
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C34H34ClN3O
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1
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| 1 |
Ki = 6.01 nM
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CP0051933
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(3-Chloro-4,5,6,7-tetrahydro-pyrazolo[1,5-a]pyridin-5-yl)-dipropyl-amine
Show/Hide
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C13H22ClN3
|
2
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| 1 |
Ki = 6.1 nM
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| 2 |
Ki = 230 nM
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CP0523746
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(E)-N-[4-(4-benzhydrylpiperazin-1-yl)butyl]-3-phenylprop-2-enamide
Show/Hide
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C30H35N3O
|
1
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| 1 |
Ki = 6.2 nM
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CP0393059
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3-ethynyl-N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]benzamide
Show/Hide
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C24H29N3O2
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1
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| 1 |
Ki = 6.2 nM
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CP0860181
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5-(4-Chloro-phenyl)-furan-2-carboxylic acid {4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-butyl}-amide oxalic acid
Show/Hide
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C28H32ClN3O7
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1
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| 1 |
Ki = 6.3 nM
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CP0436005
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(R)-N-(4-(4-Phenylbenzoylamino)butyl)-N-propyl-5-amino-4,5,6,7-tetrahydropyrazolo[1,5-a]pyridine
Show/Hide
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C27H34N4O
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2
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| 1 |
Ki = 6.3 nM
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| 2 |
Ki = 15 nM
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CP0452801
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4-bromo-N-[4-(4-phenylpiperazin-1-yl)butyl]benzamide
Show/Hide
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C21H26BrN3O
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1
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| 1 |
Ki = 6.31 nM
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CP0453338
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(2R)-5-methoxy-N,N-dipropyl-6-[2-[4-(trifluoromethyl)phenyl]ethyl]-1,2,3,4-tetrahydronaphthalen-2-amine
Show/Hide
|
C26H34F3NO
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1
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| 1 |
Ki = 6.31 nM
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CP0497077
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methyl N-[[6-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-2-yl]methyl]-N-(4-methoxyphenyl)carbamate
Show/Hide
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C26H36N2O3
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1
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| 1 |
Ki = 6.31 nM
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CP0534481
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N-[(2-chlorophenyl)methyl]-N-[[5-(5-ethylsulfonyl-2-methoxyphenyl)-1H-pyrrol-2-yl]methyl]ethanamine
Show/Hide
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C23H27ClN2O3S
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1
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| 1 |
Ki = 6.31 nM
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CP0431145
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1-[4-methoxy-3-[5-[(2-phenylazepan-1-yl)methyl]-1H-pyrrol-2-yl]phenyl]sulfonyl-3,4-dihydro-2H-quinoline
Show/Hide
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C33H37N3O3S
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1
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| 1 |
Ki = 6.31 nM
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CP0431152
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N-benzyl-N-ethyl-4-methoxy-3-[5-[(2-phenylazepan-1-yl)methyl]-1H-pyrrol-2-yl]benzenesulfonamide
Show/Hide
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C33H39N3O3S
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1
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| 1 |
Ki = 6.31 nM
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CP0466332
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4-methoxy-N-methyl-N-phenyl-3-[5-[(2-phenylazepan-1-yl)methyl]-1H-pyrrol-2-yl]benzenesulfonamide
Show/Hide
|
C31H35N3O3S
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1
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| 1 |
Ki = 6.31 nM
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CP0461103
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[(4aS,10bS)-4-[4-[(4-phenylbenzoyl)amino]butyl]-2,3,4a,5,6,10b-hexahydro-1H-benzo[f]quinolin-7-yl] methanesulfonate
Show/Hide
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C31H36N2O4S
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1
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| 1 |
Ki = 6.31 nM
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CP0490398
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(3aR,9bS)-2-[(4-fluorophenyl)methyl]-3,3a,4,9b-tetrahydro-1H-chromeno[3,4-c]pyrrole-8-carbonitrile
Show/Hide
|
C19H17FN2O
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1
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| 1 |
Ki = 6.31 nM
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CP0492432
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2-benzyl-1,3,3a,4,5,9b-hexahydrobenzo[e]isoindole-8-carbonitrile
Show/Hide
|
C20H20N2
|
1
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| 1 |
Ki = 6.31 nM
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CP0505752
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(3aS,9bR)-2-benzyl-3,3a,4,9b-tetrahydro-1H-chromeno[3,4-c]pyrrole-8-carbonitrile
Show/Hide
|
C19H18N2O
|
1
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| 1 |
Ki = 6.31 nM
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CP0384907
|
CHEMBL86032
Show/Hide
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C28H32N4O3
|
1
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| 1 |
Ki = 6.31 nM
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CP0474600
|
(E)-N-[4-[2-(7-cyano-1,2,4,5-tetrahydro-3-benzazepin-3-yl)ethyl]cyclohexyl]-3-(3-fluorophenyl)prop-2-enamide
Show/Hide
|
C28H32FN3O
|
1
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| 1 |
Ki = 6.31 nM
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CP0487375
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(E)-N-[4-[2-(7-cyano-1,2,4,5-tetrahydro-3-benzazepin-3-yl)ethyl]cyclohexyl]-3-(4-fluorophenyl)prop-2-enamide
Show/Hide
|
C28H32FN3O
|
1
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| 1 |
Ki = 6.31 nM
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CP0656167
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4'-chloro-2-methyl-biphenyl-4-sulfonic acid (3-methyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-yl)-amide
Show/Hide
|
C24H25ClN2O2S
|
1
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| 1 |
Ki = 6.31 nM
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CP0438522
|
3-(2-methyl-1,3-oxazol-5-yl)-N-[4-[2-(7-methylsulfonyl-1,2,4,5-tetrahydro-3-benzazepin-3-yl)ethyl]cyclohexyl]benzamide;hydrochloride
Show/Hide
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C30H38ClN3O4S
|
1
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| 1 |
Ki = 6.31 nM
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CP0463460
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N-[4-[2-(7-methylsulfonyl-1,2,4,5-tetrahydro-3-benzazepin-3-yl)ethyl]cyclohexyl]naphthalene-1-carboxamide;hydrochloride
Show/Hide
|
C30H37ClN2O3S
|
1
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| 1 |
Ki = 6.31 nM
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|
|
|
CP0426969
|
3-[3-[3-[[5-(2,3-dimethylquinoxalin-6-yl)-4-methyl-1,2,4-triazol-3-yl]sulfanyl]propyl]-1,2,4,5-tetrahydro-3-benzazepin-7-yl]-5-methyl-1,2-oxazole
Show/Hide
|
C30H33N7OS
|
1
|
| 1 |
Ki = 6.31 nM
|
|
|
|
CP0056386
|
5-(2-(4-(benzo[d]isothiazol-3-yl)piperazin-1-yl)ethyl)-6-chloroindolin-2-one
Show/Hide
|
C21H21ClN4OS
|
1
|
| 1 |
Ki = 6.31 nM
|
|
|
|
CP0405124
|
CAS_53583-79-2
Show/Hide
|
C17H26N2O4S
|
1
|
| 1 |
Ki = 6.31 nM
|
|
|
|
CP0201567
|
1-[2-(1,3-dihydroisoindol-2-yl)ethyl]-3-(3-propan-2-ylphenyl)imidazolidin-2-one
Show/Hide
|
C22H27N3O
|
1
|
| 1 |
Ki = 6.31 nM
|
|
|
|
CP0266800
|
1-(5-chloro-2-fluorophenyl)-3-[2-(1,3-dihydroisoindol-2-yl)ethyl]imidazolidin-2-one
Show/Hide
|
C19H19ClFN3O
|
1
|
| 1 |
Ki = 6.31 nM
|
|
|
|
CP0315217
|
1-(3-chlorophenyl)-3-[2-(3-methylpiperidin-1-yl)ethyl]imidazolidin-2-one
Show/Hide
|
C17H24ClN3O
|
1
|
| 1 |
Ki = 6.31 nM
|
|
|
|
CP0043471
|
1-(3-chlorophenyl)-3-[2-[(7,7-dimethyl-1-bicyclo[2.2.1]heptanyl)methyl-methylamino]ethyl]imidazolidin-2-one
Show/Hide
|
C22H32ClN3O
|
1
|
| 1 |
Ki = 6.31 nM
|
|
|
|
CP0039022
|
4-methyl-5-[4-methyl-5-[3-[6-[3-(trifluoromethyl)phenyl]-3-azabicyclo[4.1.0]heptan-3-yl]propylsulfanyl]-1,2,4-triazol-3-yl]-1,3-oxazole
Show/Hide
|
C23H26F3N5OS
|
1
|
| 1 |
Ki = 6.31 nM
|
|
|
|
CP0100832
|
5-[5-[3-[(1R,5S)-3-[2-fluoro-4-(trifluoromethyl)phenyl]-8-azabicyclo[3.2.1]octan-8-yl]propylsulfanyl]-4-methyl-1,2,4-triazol-3-yl]-4-methyl-1,3-oxazole
Show/Hide
|
C24H27F4N5OS
|
1
|
| 1 |
Ki = 6.31 nM
|
|
|
|
CP0380815
|
7-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy]pyrazolo[1,5-a]pyridine-3-carbaldehyde
Show/Hide
|
C22H24Cl2N4O2
|
1
|
| 1 |
Ki = 6.4 nM
|
|
|
|
CP0385663
|
bis[4-(4-chlorophenyl)-1-[4-(4-fluorophenyl)-4-oxobutyl]piperidin-4-yl] octanedioate
Show/Hide
|
C50H56Cl2F2N2O6
|
1
|
| 1 |
Ki = 6.4 nM
|
|
|
|
CP0879266
|
1-{4-[3-(2,4-Dimethoxy-phenyl)-isoxazol-5-yl]-butyl}-4-(2-methoxy-phenyl)-piperazine hydrochloride
Show/Hide
|
C26H34ClN3O4
|
1
|
| 1 |
Ki = 6.5 nM
|
|
|
|
CP0845916
|
Quinoline-2-carboxylic acid {4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-butyl}-amide oxalic acid
Show/Hide
|
C27H32N4O6
|
1
|
| 1 |
Ki = 6.6 nM
|
|
|
|
CP0237860
|
4-methyl-5-[4-methyl-5-[3-[(2S,3R)-2-phenyl-5-azaspiro[2.4]heptan-5-yl]propylsulfanyl]-1,2,4-triazol-3-yl]-1,3-oxazole
Show/Hide
|
C22H27N5OS
|
1
|
| 1 |
Ki = 6.607 nM
|
|
|
|
CP0380642
|
5-[5-[3-[(2S,3R)-2-[2-fluoro-4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptan-5-yl]propylsulfanyl]-4-methyl-1,2,4-triazol-3-yl]-4-methyl-1,3-oxazole
Show/Hide
|
C23H25F4N5OS
|
1
|
| 1 |
Ki = 6.607 nM
|
|
|
|
CP0295825
|
N,N-dipropyl-4,5,6,7-tetrahydropyrazolo[1,5-a]pyridin-5-amine
Show/Hide
|
C13H23N3
|
2
|
| 1 |
Ki = 6.7 nM
|
|
|
| 2 |
Ki = 200 nM
|
|
|
|
CP0449385
|
3-Chloro-benzo[b]thiophene-2-carboxylic acid {4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-butyl}-amide
Show/Hide
|
C24H28ClN3O2S
|
1
|
| 1 |
Ki = 6.7 nM
|
|
|
|
CP0378917
|
N-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl]naphthalene-1-carboxamide
Show/Hide
|
C25H27Cl2N3O
|
1
|
| 1 |
Ki = 6.9 nM
|
|
|
|
CP0380814
|
5-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy]pyrazolo[1,5-a]pyridine-3-carbaldehyde
Show/Hide
|
C22H24Cl2N4O2
|
1
|
| 1 |
Ki = 6.9 nM
|
|
|
|
CP0484397
|
CHEMBL4788140
Show/Hide
|
C28H35ClN2O2
|
1
|
| 1 |
Ki = 6.9 nM
|
|
|
|
CP0380805
|
5-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy]pyrazolo[1,5-a]pyridine
Show/Hide
|
C21H24Cl2N4O
|
1
|
| 1 |
Ki = 7 nM
|
|
|
|
CP0399842
|
(S)-7-Dipropylamino-5,6,7,8-tetrahydro-indolizine-3-carbonitrile
Show/Hide
|
C15H23N3
|
3
|
| 1 |
Ki = 7.2 nM
|
|
|
| 2 |
Ki = 7.244 nM
|
|
|
| 3 |
Ki = 140 nM
|
|
|
|
CP0414636
|
7-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy]pyrazolo[1,5-a]pyridine
Show/Hide
|
C21H24Cl2N4O
|
1
|
| 1 |
Ki = 7.2 nM
|
|
|
|
CP0486725
|
CHEMBL4750939
Show/Hide
|
C23H36ClN3O
|
1
|
| 1 |
Ki = 7.2 nM
|
|
|
|
CP0402936
|
[4-[2-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]ethyl]piperidin-1-yl]-(furan-2-yl)methanone
Show/Hide
|
C23H28N4O2S
|
1
|
| 1 |
Ki = 7.3 nM
|
|
|
|
CP0378012
|
4-(2-Benzylamino-ethoxy)-6-chloro-1,3-dihydro-benzoimidazol-2-one
Show/Hide
|
C16H16ClN3O2
|
1
|
| 1 |
Ki = 7.4 nM
|
|
|
|
CP0386862
|
5-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butoxy]pyrazolo[1,5-a]pyridine-2-carbaldehyde
Show/Hide
|
C23H28N4O3
|
1
|
| 1 |
Ki = 7.4 nM
|
|
|
|
CP0393753
|
ethyl 5-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butoxy]pyrazolo[1,5-a]pyridine-2-carboxylate
Show/Hide
|
C25H32N4O4
|
1
|
| 1 |
Ki = 7.4 nM
|
|
|
|
CP0179734
|
1-[(2-bromophenyl)methyl]-N-[5-[4-(2-methoxyphenyl)piperazin-1-yl]pentyl]-5-propyltriazole-4-carboxamide
Show/Hide
|
C29H39BrN6O2
|
1
|
| 1 |
Ki = 7.413 nM
|
|
|
|
CP0373346
|
N-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl]-3-(2-phenylethynyl)benzamide
Show/Hide
|
C29H29Cl2N3O
|
1
|
| 1 |
Ki = 7.5 nM
|
|
|
|
CP0446907
|
7-[4-[4-(8-hydroxy-2-oxochromen-5-yl)piperazin-1-yl]butoxy]-3,4-dihydro-1H-quinolin-2-one
Show/Hide
|
C26H29N3O5
|
1
|
| 1 |
Ki = 7.7 nM
|
|
|
|
CP0456878
|
2-Iodo-N-{4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-butyl}-benzamide
Show/Hide
|
C22H28IN3O2
|
1
|
| 1 |
Ki = 7.8 nM
|
|
|
|
CP0377872
|
N-[[6-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-2-yl]methyl]-N-(4-methoxyphenyl)acetamide
Show/Hide
|
C26H36N2O2
|
1
|
| 1 |
Ki = 7.943 nM
|
|
|
|
CP0409368
|
N-[[5-(5-ethylsulfonyl-2-methoxyphenyl)-1H-pyrrol-2-yl]methyl]-N-[(3-methoxyphenyl)methyl]ethanamine
Show/Hide
|
C24H30N2O4S
|
1
|
| 1 |
Ki = 7.943 nM
|
|
|
|
CP0457082
|
N-[4-[(4aS,10bS)-7-methoxy-2,3,4a,5,6,10b-hexahydro-1H-benzo[f]quinolin-4-yl]butyl]-4-phenylbenzamide
Show/Hide
|
C31H36N2O2
|
1
|
| 1 |
Ki = 7.943 nM
|
|
|
|
CP0491542
|
N-[4-[(4aS,10bS)-8-hydroxy-2,3,4a,5,6,10b-hexahydro-1H-benzo[f]quinolin-4-yl]butyl]-4-phenylbenzamide
Show/Hide
|
C30H34N2O2
|
1
|
| 1 |
Ki = 7.943 nM
|
|
|
|
CP0401531
|
2-benzyl-8-fluoro-3,3a,4,9b-tetrahydro-1H-chromeno[3,4-c]pyrrole
Show/Hide
|
C18H18FNO
|
1
|
| 1 |
Ki = 7.943 nM
|
|
|
|
CP0465274
|
2-[(4-fluorophenyl)methyl]-3,3a,4,9b-tetrahydro-1H-chromeno[3,4-c]pyrrole-8-carbonitrile
Show/Hide
|
C19H17FN2O
|
1
|
| 1 |
Ki = 7.943 nM
|
|
|
|
CP0505600
|
N-[4-[(2-methyl-5,6,7,8-tetrahydroquinazolin-6-yl)-propylamino]butyl]-4-phenylbenzamide
Show/Hide
|
C29H36N4O
|
1
|
| 1 |
Ki = 7.943 nM
|
|
|
|
CP0462766
|
[2-[4-[(4-phenylbenzoyl)amino]butyl]-3,4-dihydro-1H-isoquinolin-7-yl] trifluoromethanesulfonate
Show/Hide
|
C27H27F3N2O4S
|
1
|
| 1 |
Ki = 7.943 nM
|
|
|
|
CP0740421
|
Naphthalene-1-carboxylic acid {4-[2-(6-cyano-3,4-dihydro-1H-isoquinolin-2-yl)-ethyl]-cyclohexyl}-amide
Show/Hide
|
C29H32ClN3O
|
1
|
| 1 |
Ki = 7.943 nM
|
|
|
|
CP0407031
|
CHEMBL161916
Show/Hide
|
C26H31FN2O2
|
1
|
| 1 |
Ki = 7.943 nM
|
|
|
|
CP0410462
|
CHEMBL2113357
Show/Hide
|
C30H38ClN3O4S
|
1
|
| 1 |
Ki = 7.943 nM
|
|
|
|
CP0464550
|
7-(2,5-dimethylpyrazol-3-yl)-3-[3-[[4-methyl-5-[4-(trifluoromethyl)phenyl]-1,2,4-triazol-3-yl]sulfanyl]propyl]-1,2,4,5-tetrahydro-3-benzazepine
Show/Hide
|
C28H31F3N6S
|
1
|
| 1 |
Ki = 7.943 nM
|
|
|
|
CP0097602
|
2-fluoro-5-[2-oxo-3-[2-[4-(trifluoromethyl)piperidin-1-yl]ethyl]imidazolidin-1-yl]benzonitrile
Show/Hide
|
C18H20F4N4O
|
1
|
| 1 |
Ki = 7.943 nM
|
|
|
|
CP0266805
|
1-(3-chlorophenyl)-3-[2-(2-methylpiperidin-1-yl)ethyl]imidazolidin-2-one
Show/Hide
|
C17H24ClN3O
|
1
|
| 1 |
Ki = 7.943 nM
|
|
|
|
CP0276135
|
1-(3-chlorophenyl)-3-[2-(4-propan-2-ylpiperazin-1-yl)ethyl]imidazolidin-2-one
Show/Hide
|
C18H27ClN4O
|
1
|
| 1 |
Ki = 7.943 nM
|
|
|
|
CP0039021
|
4-methyl-5-[4-methyl-5-[3-[1-[4-(trifluoromethyl)phenyl]-3-azabicyclo[4.1.0]heptan-3-yl]propylsulfanyl]-1,2,4-triazol-3-yl]-1,3-oxazole
Show/Hide
|
C23H26F3N5OS
|
1
|
| 1 |
Ki = 7.943 nM
|
|
|
|
CP0192344
|
5-[5-[3-(7-bromospiro[1,2-dihydroindene-3,3'-pyrrolidine]-1'-yl)propylsulfanyl]-4-methyl-1,2,4-triazol-3-yl]-4-methyl-1,3-oxazole
Show/Hide
|
C22H26BrN5OS
|
1
|
| 1 |
Ki = 7.943 nM
|
|
|
|
CP0340827
|
5-[5-[3-(7-bromospiro[2,3-dihydro-1H-naphthalene-4,3'-pyrrolidine]-1'-yl)propylsulfanyl]-4-methyl-1,2,4-triazol-3-yl]-4-methyl-1,3-oxazole
Show/Hide
|
C23H28BrN5OS
|
1
|
| 1 |
Ki = 7.943 nM
|
|
|
|
CP0488269
|
4-tert-Butyl-N-{4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-butyl}-benzamide
Show/Hide
|
C26H37N3O2
|
1
|
| 1 |
Ki = 7.99 nM
|
|
|
|
CP0505107
|
N-butyl-N-[3-[4-[1-[(E)-4-[2-[4-[3-(dibutylamino)propoxy]phenyl]benzimidazol-1-yl]but-2-enyl]benzimidazol-2-yl]phenoxy]propyl]butan-1-amine
Show/Hide
|
C52H70N6O2
|
1
|
| 1 |
Ki = 8 nM
|
|
|
|
CP0042262
|
N-[(1-ethylpyrrolidin-2-yl)methyl]-2-methoxy-5-sulfamoylbenzamide
Show/Hide
|
C15H23N3O4S
|
1
|
| 1 |
Ki = 8 nM
|
|
|
|
CP0067392
|
2-{4-[3-(4-Pyridin-2-yl-piperazin-1-yl)-propoxy]-phenyl}-1H-benzoimidazole
Show/Hide
|
C25H27N5O
|
1
|
| 1 |
Ki = 8 nM
|
|
|
|
CP0436776
|
N-[4-[2-[4-(4-chlorophenyl)piperazin-1-yl]ethyl]cyclohexyl]thiophene-2-carboxamide
Show/Hide
|
C23H30ClN3OS
|
1
|
| 1 |
Ki = 8 nM
|
|
|
|
CP0426179
|
CHEMBL4761274
Show/Hide
|
C23H35ClN2O
|
1
|
| 1 |
Ki = 8.1 nM
|
|
|
|
CP0530412
|
CHEMBL4756826
Show/Hide
|
C23H33ClN2O
|
1
|
| 1 |
Ki = 8.2 nM
|
|
|
|
CP0293355
|
3-{[4-(4-Methoxyphenyl)piperazin-1-yl]methyl}2,5,7-rimethylimidazo[1,2-c]pyrimidine
Show/Hide
|
C21H27N5O
|
1
|
| 1 |
Ki = 8.5 nM
|
|
|
|
CP0413703
|
5-[4-[2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl]triazol-1-yl]pyrazolo[1,5-a]pyridine-3-carbaldehyde
Show/Hide
|
C23H25N7O2
|
1
|
| 1 |
Ki = 8.5 nM
|
|
|
|
CP0413704
|
5-[4-[3-[4-(2,3-dichlorophenyl)piperazin-1-yl]propyl]triazol-1-yl]pyrazolo[1,5-a]pyridine
Show/Hide
|
C22H23Cl2N7
|
1
|
| 1 |
Ki = 8.5 nM
|
|
|
|
CP0446910
|
8-hydroxy-5-[4-(4-pyrazolo[1,5-a]pyridin-5-yloxybutyl)piperazin-1-yl]chromen-2-one
Show/Hide
|
C24H26N4O4
|
1
|
| 1 |
Ki = 8.5 nM
|
|
|
|
CP0881183
|
1-benzyl-N-(5-(4-(2,3-dichlorophenyl)piperazin-1-yl)pentyl)-5-methyl-1H-1,2,3-triazole-4-carboxamide
Show/Hide
|
C26H32Cl2N6O
|
1
|
| 1 |
Ki = 8.511 nM
|
|
|
|
CP0404378
|
N-[4-[[(1R)-4-ethynylcyclohex-3-en-1-yl]-propylamino]butyl]pyrazolo[1,5-a]pyridine-3-carboxamide
Show/Hide
|
C23H30N4O
|
1
|
| 1 |
Ki = 8.6 nM
|
|
|
|
CP0402937
|
ethyl 4-[2-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]ethyl]piperidine-1-carboxylate
Show/Hide
|
C21H30N4O2S
|
1
|
| 1 |
Ki = 8.7 nM
|
|
|
|
CP0460991
|
(E)-N-[4-(3,4-dihydro-1H-isoquinolin-2-yl)butyl]-3-phenylprop-2-enamide
Show/Hide
|
C22H26N2O
|
1
|
| 1 |
Ki = 8.72 nM
|
|
|
|
CP0372695
|
Benzyl-[2-(1H-indazol-4-yloxy)-ethyl]-amine
Show/Hide
|
C16H17N3O
|
1
|
| 1 |
Ki = 8.8 nM
|
|
|
|
CP0503564
|
2-[4-(3-pyrrolidin-1-ylpropoxy)phenyl]-1-[(E)-4-[2-[4-(3-pyrrolidin-1-ylpropoxy)phenyl]benzimidazol-1-yl]but-2-enyl]benzimidazole
Show/Hide
|
C44H50N6O2
|
1
|
| 1 |
Ki = 9 nM
|
|
|
|
CP0915789
|
1-(2-Ethoxy-phenyl)-4-[4-(3-phenyl-isoxazol-5-yl)-butyl]-piperazine hydrochloride
Show/Hide
|
C25H32ClN3O2
|
1
|
| 1 |
Ki = 9 nM
|
|
|
|
CP0393147
|
6-Fluoro-pyridine-2-carboxylic acid {4-[4-(2,3-dichloro-phenyl)-piperazin-1-yl]-butyl}-amide
Show/Hide
|
C20H23Cl2FN4O
|
1
|
| 1 |
Ki = 9 nM
|
|
|
|
CP0385665
|
bis[4-(4-chlorophenyl)-1-[4-(4-fluorophenyl)-4-oxobutyl]piperidin-4-yl] nonanedioate
Show/Hide
|
C51H58Cl2F2N2O6
|
1
|
| 1 |
Ki = 9.1 nM
|
|
|
|
CP0935366
|
3-Iodo-N-{4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-butyl}-benzamide oxalic acid
Show/Hide
|
C24H30IN3O6
|
1
|
| 1 |
Ki = 9.2 nM
|
|
|
|
CP0486718
|
CHEMBL4762024
Show/Hide
|
C27H37ClN2O2
|
1
|
| 1 |
Ki = 9.3 nM
|
|
|
|
CP0905327
|
1-(2-Methoxy-phenyl)-4-[4-(3-phenyl-isoxazol-5-yl)-butyl]-piperazine hydrochloride
Show/Hide
|
C24H30ClN3O2
|
1
|
| 1 |
Ki = 9.5 nM
|
|
|
|
CP0412174
|
[4-(4-chlorophenyl)-1-[4-(4-fluorophenyl)-4-oxobutyl]piperidin-4-yl] 3-[4-[3-[4-(4-chlorophenyl)-1-[4-(4-fluorophenyl)-4-oxobutyl]piperidin-4-yl]oxy-3-oxopropyl]piperazin-1-yl]propanoate
Show/Hide
|
C52H60Cl2F2N4O6
|
1
|
| 1 |
Ki = 9.5 nM
|
|
|
|
CP0484398
|
(2S)-N-[4-[2-[(5R)-7-chloro-5-methyl-1,2,4,5-tetrahydro-3-benzazepin-3-yl]ethyl]cyclohexyl]pyrrolidine-2-carboxamide
Show/Hide
|
C24H36ClN3O
|
1
|
| 1 |
Ki = 9.5 nM
|
|
|
|
CP0420085
|
4-[2-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]ethyl]cyclohexan-1-amine
Show/Hide
|
C19H28N4S
|
1
|
| 1 |
Ki = 9.6 nM
|
|
|
|
CP0880910
|
Isoquinoline-1-carboxylic acid {4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-butyl}-amide oxalic acid
Show/Hide
|
C27H32N4O6
|
1
|
| 1 |
Ki = 9.62 nM
|
|
|
|
CP0483373
|
[4-(4-chlorophenyl)-1-[4-(4-fluorophenyl)-4-oxobutyl]piperidin-4-yl] 3-[1-[2-[2-[2-[2-[4-[3-[4-(4-chlorophenyl)-1-[4-(4-fluorophenyl)-4-oxobutyl]piperidin-4-yl]oxy-3-oxopropyl]triazol-1-yl]ethoxy]ethoxy]ethoxy]ethyl]triazol-4-yl]propanoate
Show/Hide
|
C60H70Cl2F2N8O9
|
1
|
| 1 |
Ki = 9.8 nM
|
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CP0373623
|
4-[4-([2.2]Paracyclophan-4-yl)piperazin-1-yl]-1-(4-fluorophenyl)-butan-1-one
Show/Hide
|
C30H33FN2O
|
1
|
| 1 |
Ki = 9.9 nM
|
|
|
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CP0405619
|
2-[4-(3-piperidin-1-ylpropoxy)phenyl]-1-[(E)-4-[2-[4-(3-piperidin-1-ylpropoxy)phenyl]benzimidazol-1-yl]but-2-enyl]benzimidazole
Show/Hide
|
C46H54N6O2
|
1
|
| 1 |
Ki = 10 nM
|
|
|
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CP0454642
|
(2S)-6-[2-(4-chlorophenyl)ethyl]-N,N-dipropyl-1,2,3,4-tetrahydronaphthalen-2-amine
Show/Hide
|
C24H32ClN
|
1
|
| 1 |
Ki = 10 nM
|
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|
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CP0398025
|
N-[[5-(5-ethylsulfonyl-2-methoxyphenyl)-1H-pyrrol-2-yl]methyl]-N-[(2-methoxyphenyl)methyl]ethanamine
Show/Hide
|
C24H30N2O4S
|
1
|
| 1 |
Ki = 10 nM
|
|
|
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CP0466734
|
2-[(2S,5S)-1-ethyl-5-phenylpyrrolidin-2-yl]-5-(5-ethylsulfonyl-2-methoxyphenyl)-1H-pyrrole
Show/Hide
|
C25H30N2O3S
|
1
|
| 1 |
Ki = 10 nM
|
|
|
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CP0505792
|
2-(1-benzylpyrrolidin-2-yl)-5-(5-ethylsulfonyl-2-methoxyphenyl)-1H-pyrrole
Show/Hide
|
C24H28N2O3S
|
1
|
| 1 |
Ki = 10 nM
|
|
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CP0502763
|
phenyl 4-methoxy-3-[5-[(2-phenylazepan-1-yl)methyl]-1H-pyrrol-2-yl]benzenesulfonate
Show/Hide
|
C30H32N2O4S
|
1
|
| 1 |
Ki = 10 nM
|
|
|
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CP0425340
|
(4aR,11bR)-4-propyl-2,3,4a,5,6,8,9,11b-octahydro-[1]benzofuro[5,6-h][1,4]benzoxazine
Show/Hide
|
C17H23NO2
|
1
|
| 1 |
Ki = 10 nM
|
|
|
|
CP0460767
|
[4-[4-[(4-phenylbenzoyl)amino]butyl]-2,3,4a,5,6,10b-hexahydro-1H-benzo[f]quinolin-7-yl] methanesulfonate
Show/Hide
|
C31H36N2O4S
|
1
|
| 1 |
Ki = 10 nM
|
|
|
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CP0505753
|
N-[4-[[(3aR,9bS)-8-cyano-3,3a,4,9b-tetrahydro-1H-chromeno[3,4-c]pyrrol-2-yl]methyl]phenyl]acetamide
Show/Hide
|
C21H21N3O2
|
1
|
| 1 |
Ki = 10 nM
|
|
|
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CP0412049
|
N-[4-[(2-amino-5,6,7,8-tetrahydroquinazolin-6-yl)-methylamino]butyl]-4-phenylbenzamide
Show/Hide
|
C26H31N5O
|
1
|
| 1 |
Ki = 10 nM
|
|
|
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CP0448507
|
6-N-propyl-4,5,6,7-tetrahydro-1,3-benzothiazole-2,6-diamine
Show/Hide
|
C10H17N3S
|
1
|
| 1 |
Ki = 10 nM
|
|
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CP0489980
|
[2-[4-[[(E)-3-(1-methyl-2-oxoquinolin-6-yl)prop-2-enoyl]amino]butyl]-3,4-dihydro-1H-isoquinolin-7-yl] trifluoromethanesulfonate
Show/Hide
|
C27H28F3N3O5S
|
1
|
| 1 |
Ki = 10 nM
|
|
|
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CP0410033
|
3-[2-(4-phenyl-3,6-dihydro-2H-pyridin-1-yl)ethyl]-1H-pyrrolo[2,3-b]pyridine
Show/Hide
|
C20H21N3
|
1
|
| 1 |
Ki = 10 nM
|
|
|
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CP0701210
|
Naphthalene-2-carboxylic acid {4-[2-(6-cyano-3,4-dihydro-1H-isoquinolin-2-yl)-ethyl]-cyclohexyl}-amide
Show/Hide
|
C29H32ClN3O
|
1
|
| 1 |
Ki = 10 nM
|
|
|
|
CP0740448
|
Quinoline-4-carboxylic acid {4-[2-(6-cyano-3,4-dihydro-1H-isoquinolin-2-yl)-ethyl]-cyclohexyl}-amide HCl (SB-277011)
Show/Hide
|
C28H31ClN4O
|
1
|
| 1 |
Ki = 10 nM
|
|
|
|
CP0379114
|
CHEMBL315209
Show/Hide
|
C28H32FN3O
|
1
|
| 1 |
Ki = 10 nM
|
|
|
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CP0431702
|
N-[4-[2-(7-cyano-1,2,4,5-tetrahydro-3-benzazepin-3-yl)ethyl]cyclohexyl]-2-oxo-1H-quinoline-7-carboxamide
Show/Hide
|
C29H32N4O2
|
1
|
| 1 |
Ki = 10 nM
|
|
|
|
CP0461054
|
CHEMBL161853
Show/Hide
|
C27H31N3O2
|
1
|
| 1 |
Ki = 10 nM
|
|
|
|
CP0539021
|
CHEMBL161126
Show/Hide
|
C26H28F4N2O
|
1
|
| 1 |
Ki = 10 nM
|
|
|
|
CP0869075
|
1-(2-Fluoro-phenyl)-4-[4-(3-styryl-isoxazol-5-yl)-butyl]-piperazine hydrochloride
Show/Hide
|
C25H29ClFN3O
|
1
|
| 1 |
Ki = 10 nM
|
|
|
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CP0400123
|
N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]-4-(2-phenylethynyl)benzamide
Show/Hide
|
C30H33N3O2
|
1
|
| 1 |
Ki = 10 nM
|
|
|
|
CP0404762
|
5-methyl-3-[3-[3-[[4-methyl-5-(trifluoromethyl)-1,2,4-triazol-3-yl]sulfanyl]propyl]-1,2,4,5-tetrahydro-3-benzazepin-7-yl]-1,2-oxazole
Show/Hide
|
C21H24F3N5OS
|
1
|
| 1 |
Ki = 10 nM
|
|
|
|
CP0440408
|
5-methyl-3-[3-[3-[(4-methyl-5-propan-2-yl-1,2,4-triazol-3-yl)sulfanyl]propyl]-1,2,4,5-tetrahydro-3-benzazepin-7-yl]-1,2-oxazole
Show/Hide
|
C23H31N5OS
|
1
|
| 1 |
Ki = 10 nM
|
|
|
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CP0039958
|
(risperidone)3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one
Show/Hide
|
C23H27FN4O2
|
1
|
| 1 |
Ki = 10 nM
|
|
|
|
CP0461858
|
1-[1-[5-(5-ethylsulfonyl-2-methoxyphenyl)-1H-pyrrol-2-yl]ethyl]piperidine
Show/Hide
|
C20H28N2O3S
|
1
|
| 1 |
Ki = 10 nM
|
|
|
|
CP0089216
|
1-(3-methoxyphenyl)-3-[2-[4-(trifluoromethyl)piperidin-1-yl]ethyl]imidazolidin-2-one
Show/Hide
|
C18H24F3N3O2
|
1
|
| 1 |
Ki = 10 nM
|
|
|
|
CP0043472
|
CHEMBL562948
Show/Hide
|
C22H33N3O
|
1
|
| 1 |
Ki = 10 nM
|
|
|
|
CP0047125
|
8-(3-{[4-Methyl-5-(4-methyl-1,3-oxazol-5-yl)-4H-1,2,4-triazol-3-yl]thio}propyl)-3-[4-(trifluoromethyl)phenyl]-8-azabicyclo[3.2.1]-octane
Show/Hide
|
C24H28F3N5OS
|
1
|
| 1 |
Ki = 10 nM
|
|
|
|
CP0283518
|
2,4-dimethyl-5-[4-methyl-5-[3-[1-[4-(trifluoromethyl)phenyl]-4-azabicyclo[5.1.0]octan-4-yl]propylsulfanyl]-1,2,4-triazol-3-yl]-1,3-oxazole
Show/Hide
|
C25H30F3N5OS
|
1
|
| 1 |
Ki = 10 nM
|
|
|
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CP0372556
|
N-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]-5-[2-[2-[2-[2-[[3-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propylcarbamoyl]pyrazolo[1,5-a]pyridin-5-yl]methoxy]ethoxy]ethoxy]ethoxy]ethoxymethyl]pyrazolo[1,5-a]pyridine-3-carboxamide
Show/Hide
|
C54H72N10O9
|
1
|
| 1 |
Ki = 10 nM
|
|
|
|
CP0375872
|
N-[4-[[(1S)-4-ethynylcyclohex-3-en-1-yl]-propylamino]butyl]pyrazolo[1,5-a]pyridine-3-carboxamide
Show/Hide
|
C23H30N4O
|
1
|
| 1 |
Ki = 10 nM
|
|
|
|
CP0407055
|
N-[4-[[(1S)-4-ethynylcyclohex-3-en-1-yl]-propylamino]butyl]pyrazolo[1,5-a]pyridine-2-carboxamide
Show/Hide
|
C23H30N4O
|
1
|
| 1 |
Ki = 10 nM
|
|
|
|
CP0414637
|
4-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy]pyrazolo[1,5-a]pyridine
Show/Hide
|
C21H24Cl2N4O
|
1
|
| 1 |
Ki = 10 nM
|
|
|
|
CP0455944
|
4-[3-[[4-methyl-5-[4-(5-methyl-1,2,4-oxadiazol-3-yl)phenyl]-1,2,4-triazol-3-yl]sulfanyl]propyl]-2-[4-(trifluoromethyl)phenyl]morpholine
Show/Hide
|
C26H27F3N6O2S
|
2
|
| 1 |
Ki = 10 nM
|
|
|
| 2 |
Ki > 10000 nM
|
|
|
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CP0399463
|
4-[4-methyl-5-[3-[(2R,3S)-2-[4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptan-5-yl]propylsulfanyl]-1,2,4-triazol-3-yl]piperidin-2-one
Show/Hide
|
C24H30F3N5OS
|
1
|
| 1 |
Ki = 10 nM
|
|
|
|
CP0399464
|
1-methyl-4-[4-methyl-5-[3-[(2R,3S)-2-[4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptan-5-yl]propylsulfanyl]-1,2,4-triazol-3-yl]piperidin-2-one
Show/Hide
|
C25H32F3N5OS
|
1
|
| 1 |
Ki = 10 nM
|
|
|
|
CP0496544
|
(E)-N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]-3-(4-phenoxyphenyl)prop-2-enamide
Show/Hide
|
C30H35N3O3
|
1
|
| 1 |
Ki = 10.1 nM
|
|
|
|
CP0886671
|
3-(4-tert-Butyl-phenyl)-N-{4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-butyl}-acrylamide oxalic acid
Show/Hide
|
C30H41N3O6
|
1
|
| 1 |
Ki = 10.2 nM
|
|
|
|
CP0376081
|
7-(4-Phenyl-piperazin-1-ylmethyl)-4H-benzo[1,4]oxazin-3-one
Show/Hide
|
C19H21N3O2
|
1
|
| 1 |
Ki = 10.4 nM
|
|
|
|
CP0541054
|
N-[4-[4-(4-chlorophenyl)piperazin-1-yl]butyl]naphthalene-2-carboxamide
Show/Hide
|
C25H28ClN3O
|
1
|
| 1 |
Ki = 10.4 nM
|
|
|
|
CP0515742
|
N-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl]-4-phenylcyclohexane-1-carboxamide
Show/Hide
|
C27H35Cl2N3O
|
1
|
| 1 |
Ki = 10.6 nM
|
|
|
|
CP0511133
|
(E)-N-[4-[4-(2-methoxyanilino)piperidin-1-yl]butyl]-3-phenylprop-2-enamide
Show/Hide
|
C25H33N3O2
|
1
|
| 1 |
Ki = 10.8 nM
|
|
|
|
CP0409214
|
N-[4-[4-(8-oxo-6-thiatricyclo[8.4.0.03,7]tetradeca-1(14),3(7),4,10,12-pentaen-2-ylidene)piperidin-1-yl]butyl]naphthalene-2-carboxamide
Show/Hide
|
C33H32N2O2S
|
1
|
| 1 |
Ki = 10.9 nM
|
|
|
|
CP0416783
|
1-benzyl-N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]-5-propyltriazole-4-carboxamide
Show/Hide
|
C28H38N6O2
|
1
|
| 1 |
Ki = 10.96 nM
|
|
|
|
CP0297087
|
3-(2-Benzylamino-ethoxy)-phenol
Show/Hide
|
C15H17NO2
|
1
|
| 1 |
Ki = 11 nM
|
|
|
|
CP0501098
|
N-[5-[2-(benzylamino)ethoxy]-2-chlorophenyl]methanesulfonamide
Show/Hide
|
C16H19ClN2O3S
|
1
|
| 1 |
Ki = 11 nM
|
|
|
|
CP0455078
|
5-iodo-2-methoxy-N-[[(2S)-1-prop-2-enylpyrrolidin-2-yl]methyl]benzamide
Show/Hide
|
C16H21IN2O2
|
1
|
| 1 |
Ki = 11 nM
|
|
|
|
CP0535737
|
1-(4-fluoro-phenyl)-4-(3,4,6,7,12,12a-hexahydro-1H-pyrazino[1',2':1,6]pyrido[3,4-b]indol-2-yl)-butan-1-one
Show/Hide
|
C24H26FN3O
|
1
|
| 1 |
Ki = 11 nM
|
|
|
|
CP0382586
|
N-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]-3-[2-[2-[2-[2-[3-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propylcarbamoyl]phenoxy]ethoxy]ethoxy]ethoxy]ethoxy]benzamide
Show/Hide
|
C50H68N6O9
|
1
|
| 1 |
Ki = 11 nM
|
|
|
|
CP0428645
|
N-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]-4-[2-[2-[2-[2-[2-[2-[[4-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propylcarbamoyl]phenyl]methoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxymethyl]benzamide
Show/Hide
|
C56H80N6O11
|
1
|
| 1 |
Ki = 11 nM
|
|
|
|
CP0385662
|
bis[4-(4-chlorophenyl)-1-[4-(4-fluorophenyl)-4-oxobutyl]piperidin-4-yl] hexanedioate
Show/Hide
|
C48H52Cl2F2N2O6
|
1
|
| 1 |
Ki = 11 nM
|
|
|
|
CP0481705
|
bis[4-(4-chlorophenyl)-1-[4-(4-fluorophenyl)-4-oxobutyl]piperidin-4-yl] heptanedioate
Show/Hide
|
C49H54Cl2F2N2O6
|
1
|
| 1 |
Ki = 11 nM
|
|
|
|
CP0405798
|
(6R)-6-[propyl(4-pyrazolo[1,5-a]pyridin-6-yloxybutyl)amino]-5,6,7,8-tetrahydronaphthalen-1-ol
Show/Hide
|
C24H31N3O2
|
1
|
| 1 |
Ki = 11 nM
|
|
|
|
CP0426895
|
N-[4-(4-benzhydrylpiperazin-1-yl)butyl]naphthalene-2-carboxamide
Show/Hide
|
C32H35N3O
|
1
|
| 1 |
Ki = 11.1 nM
|
|
|
|
CP0378915
|
N-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl]benzamide
Show/Hide
|
C21H25Cl2N3O
|
1
|
| 1 |
Ki = 11.9 nM
|
|
|
|
CP0902338
|
1-{4-[3-(4-Fluoro-phenyl)-isoxazol-5-yl]-butyl}-4-phenyl-piperazine hydrochloride
Show/Hide
|
C23H27ClFN3O
|
1
|
| 1 |
Ki = 12 nM
|
|
|
|
CP0291607
|
3,4-Dihydro-2-[4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl]-5-phenylisoquinolin-1(2H)-one
Show/Hide
|
C30H35N3O2
|
1
|
| 1 |
Ki = 12 nM
|
|
|
|
CP0400541
|
3-methoxy-4-[3-[1-[8-[4-[3-[2-methoxy-4-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butylcarbamoyl]phenoxy]propyl]triazol-1-yl]octyl]triazol-4-yl]propoxy]-N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]benzamide
Show/Hide
|
C64H90N12O8
|
1
|
| 1 |
Ki = 12 nM
|
|
|
|
CP0413701
|
5-[4-[3-[4-(2,3-dichlorophenyl)piperazin-1-yl]propyl]triazol-1-yl]pyrazolo[1,5-a]pyridine-3-carbaldehyde
Show/Hide
|
C23H23Cl2N7O
|
1
|
| 1 |
Ki = 12 nM
|
|
|
|
CP0566754
|
3-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]-1-methyl-1-phenylurea
Show/Hide
|
C23H32N4O2
|
1
|
| 1 |
Ki = 12 nM
|
|
|
|
CP0399133
|
4-[2-[2-[3-methoxy-4-(3-phenylpropoxy)phenyl]ethylamino]ethyl]benzene-1,2-diol
Show/Hide
|
C26H31NO4
|
1
|
| 1 |
Ki = 12 nM
|
|
|
|
CP0387292
|
5-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butoxy]pyrazolo[1,5-a]pyridine-2-carbonitrile
Show/Hide
|
C23H27N5O2
|
1
|
| 1 |
Ki = 12 nM
|
|
|
|
CP0393751
|
5-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butoxy]pyrazolo[1,5-a]pyridine-3-carbaldehyde
Show/Hide
|
C23H28N4O3
|
1
|
| 1 |
Ki = 12 nM
|
|
|
|
CP0458292
|
8-hydroxy-5-[4-[4-[(2-oxo-3,4-dihydro-1H-quinolin-7-yl)oxy]butyl]piperazin-1-yl]-1H-quinolin-2-one
Show/Hide
|
C26H30N4O4
|
1
|
| 1 |
Ki = 12 nM
|
|
|
|
CP0383485
|
4-(2-Benzylamino-ethoxy)-6-chloro-1,3-dihydro-benzoimidazole-2-thione
Show/Hide
|
C16H16ClN3OS
|
1
|
| 1 |
Ki = 12.2 nM
|
|
|
|
CP0485814
|
N-[4-[4-[(4-chlorophenyl)-phenylmethyl]piperazin-1-yl]butyl]cyclohexanecarboxamide
Show/Hide
|
C28H38ClN3O
|
1
|
| 1 |
Ki = 12.3 nM
|
|
|
|
CP0448713
|
N-[4-[2-[4-(4-methoxyphenyl)piperazin-1-yl]ethyl]cyclohexyl]thiophene-2-carboxamide
Show/Hide
|
C24H33N3O2S
|
1
|
| 1 |
Ki = 12.4 nM
|
|
|
|
CP0394422
|
4-[2-[6-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-2-yl]ethyl]phenol
Show/Hide
|
C24H33NO
|
1
|
| 1 |
Ki = 12.59 nM
|
|
|
|
CP0410129
|
N-[(3,4-dimethoxyphenyl)methyl]-N-[[5-(5-ethylsulfonyl-2-methoxyphenyl)-1H-pyrrol-2-yl]methyl]ethanamine
Show/Hide
|
C25H32N2O5S
|
1
|
| 1 |
Ki = 12.59 nM
|
|
|
|
CP0514036
|
(2,3,5,6,7,8-Hexahydro-naphtho[2,3-b]furan-7-yl)-dipropyl-amine
Show/Hide
|
C18H27NO
|
2
|
| 1 |
Ki = 12.59 nM
|
|
|
| 2 |
Ki = 13 nM
|
|
|
|
CP0555166
|
N-[4-[(3aS,9bS)-7-hydroxy-1,2,3a,4,5,9b-hexahydrobenzo[e]indol-3-yl]butyl]-4-phenylbenzamide
Show/Hide
|
C29H32N2O2
|
1
|
| 1 |
Ki = 12.59 nM
|
|
|
|
CP0521995
|
N-[4-[(8-cyano-3,3a,4,9b-tetrahydro-1H-chromeno[3,4-c]pyrrol-2-yl)methyl]phenyl]acetamide
Show/Hide
|
C21H21N3O2
|
1
|
| 1 |
Ki = 12.59 nM
|
|
|
|
CP0406281
|
N-[4-[(2-tert-butyl-5,6,7,8-tetrahydroquinazolin-6-yl)-propylamino]butyl]-4-phenylbenzamide
Show/Hide
|
C32H42N4O
|
1
|
| 1 |
Ki = 12.59 nM
|
|
|
|
CP0648872
|
N-[4-(7-Cyano-3,4-dihydro-1H-isoquinolin-2-yl)-butyl]-3-(1H-indol-3-yl)-acrylamide
Show/Hide
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C25H27ClN4O
|
1
|
| 1 |
Ki = 12.59 nM
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CP0409054
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N-[4-[2-(7-cyano-1,2,4,5-tetrahydro-3-benzazepin-3-yl)ethyl]cyclohexyl]quinoline-5-carboxamide
Show/Hide
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C29H32N4O
|
1
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| 1 |
Ki = 12.59 nM
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CP0454732
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(E)-N-[4-[2-(5-cyano-1,3-dihydroisoindol-2-yl)ethyl]cyclohexyl]-3-(4-fluorophenyl)prop-2-enamide
Show/Hide
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C26H28FN3O
|
1
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| 1 |
Ki = 12.59 nM
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CP0486356
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5-[5-[3-[7-(2,5-dimethylpyrazol-3-yl)-1,2,4,5-tetrahydro-3-benzazepin-3-yl]propylsulfanyl]-4-methyl-1,2,4-triazol-3-yl]-4-methyl-1,3-oxazole
Show/Hide
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C25H31N7OS
|
1
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| 1 |
Ki = 12.59 nM
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CP0266802
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1-[2-(1,3-dihydroisoindol-2-yl)ethyl]-3-[[3-(trifluoromethyl)phenyl]methyl]imidazolidin-2-one
Show/Hide
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C21H22F3N3O
|
1
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| 1 |
Ki = 12.59 nM
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CP0275362
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1-(3,4-dichlorophenyl)-3-[2-(1,3-dihydroisoindol-2-yl)ethyl]imidazolidin-2-one
Show/Hide
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C19H19Cl2N3O
|
1
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| 1 |
Ki = 12.59 nM
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CP0092517
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1-(3-chlorophenyl)-3-[2-[(1S,5R)-1,3,3-trimethyl-6-azabicyclo[3.2.1]octan-6-yl]ethyl]imidazolidin-2-one
Show/Hide
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C21H30ClN3O
|
1
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| 1 |
Ki = 12.59 nM
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CP0363682
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N-[4-[(5-methoxy-1,2,3,4-tetrahydronaphthalen-2-yl)-methylamino]butyl]-4-phenylbenzamide
Show/Hide
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C29H34N2O2
|
1
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| 1 |
Ki = 12.59 nM
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CP0225967
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4-methyl-5-[4-methyl-5-[3-(1-phenyl-3-azabicyclo[3.1.0]hexan-3-yl)propylsulfanyl]-1,2,4-triazol-3-yl]-1,3-oxazole
Show/Hide
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C21H25N5OS
|
1
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| 1 |
Ki = 12.59 nM
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CP0042187
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4-methyl-5-[4-methyl-5-[3-[1-[3-(trifluoromethyl)phenyl]-3-azabicyclo[4.1.0]heptan-3-yl]propylsulfanyl]-1,2,4-triazol-3-yl]-1,3-oxazole
Show/Hide
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C23H26F3N5OS
|
1
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| 1 |
Ki = 12.59 nM
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CP0383147
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4-[3-[[4-methyl-5-[4-(1,3,4-oxadiazol-2-yl)phenyl]-1,2,4-triazol-3-yl]sulfanyl]propyl]-2-[4-(trifluoromethyl)phenyl]morpholine
Show/Hide
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C25H25F3N6O2S
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2
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| 1 |
Ki = 12.59 nM
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| 2 |
Ki > 10000 nM
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CP0071763
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N-[4-[4-(2-hydroxyphenyl)piperazin-1-yl]butyl]naphthalene-2-carboxamide
Show/Hide
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C25H29N3O2
|
1
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| 1 |
Ki = 12.7 nM
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CP0172631
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1-[(4-methoxyphenyl)methyl]-N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]-5-propyltriazole-4-carboxamide
Show/Hide
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C29H40N6O3
|
1
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| 1 |
Ki = 12.88 nM
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CP0389511
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N-[4-[4-(4-phenylphenyl)triazol-1-yl]butyl]-N-propyl-4-(2-trimethylsilylethynyl)cyclohex-3-en-1-amine
Show/Hide
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C32H42N4Si
|
1
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| 1 |
Ki = 13 nM
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CP0387634
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(6R)-6-[propyl(4-pyrazolo[1,5-a]pyridin-5-yloxybutyl)amino]-5,6,7,8-tetrahydronaphthalen-1-ol
Show/Hide
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C24H31N3O2
|
1
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| 1 |
Ki = 13 nM
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CP0405812
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N-[3-[(Z)-hydroxyiminomethyl]pyrazolo[1,5-a]pyridin-5-yl]-4-[4-(2-methoxyphenyl)piperazin-1-yl]butanamide
Show/Hide
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C23H28N6O3
|
1
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| 1 |
Ki = 13 nM
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CP0432598
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6-Fluoro-N-{4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-butyl}-nicotinamide
Show/Hide
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C21H27FN4O2
|
1
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| 1 |
Ki = 14 nM
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CP0371911
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2-(4-(4-(3-a,a,a-trifluorotolyl)-1-piperazinyl)butyl)-1-isoindolinone
Show/Hide
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C23H26F3N3O
|
1
|
| 1 |
Ki = 14 nM
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CP0398765
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bis[4-(4-chlorophenyl)-1-[4-(4-fluorophenyl)-4-oxobutyl]piperidin-4-yl] butanedioate
Show/Hide
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C46H48Cl2F2N2O6
|
1
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| 1 |
Ki = 14 nM
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CP0415191
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(E)-N-[2-[2,3-dihydro-1H-inden-2-yl(propyl)amino]ethyl]-3-(4-fluorophenyl)prop-2-enamide
Show/Hide
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C23H27FN2O
|
1
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| 1 |
Ki = 14 nM
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CP0406822
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4-(4-Benzyl-piperazin-1-yl)-2-trifluoromethyl-1H-benzoimidazole
Show/Hide
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C19H19F3N4
|
1
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| 1 |
Ki = 14.7 nM
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CP0515780
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N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]-1,3-benzodioxole-5-carboxamide
Show/Hide
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C23H29N3O4
|
1
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| 1 |
Ki = 14.7 nM
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CP0885952
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3-(3-Iodo-4,5-dimethoxy-phenyl)-N-{4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-butyl}-acrylamide oxalic acid
Show/Hide
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C28H36IN3O8
|
1
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| 1 |
Ki = 14.9 nM
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CP0859683
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1-Phenyl-4-[4-(3-thiophen-2-yl-isoxazol-5-yl)-butyl]-piperazine hydrochloride
Show/Hide
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C21H26ClN3OS
|
1
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| 1 |
Ki = 15 nM
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CP0869073
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1-Benzhydryl-4-[4-(3-phenyl-isoxazol-5-yl)-butyl]-piperazine hydrochloride
Show/Hide
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C30H34ClN3O
|
1
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| 1 |
Ki = 15 nM
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CP0914731
|
1-(2-Methoxy-phenyl)-4-[4-(3-styryl-isoxazol-5-yl)-butyl]-piperazine hydrochloride
Show/Hide
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C26H32ClN3O2
|
1
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| 1 |
Ki = 15 nM
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CP0437725
|
4-(3-Piperidin-1-yl-propoxy)-benzoic acid 2-{4-[3-(2-trifluoromethyl-phenothiazin-10-yl)-propyl]-piperazin-1-yl}-ethyl ester
Show/Hide
|
C37H45F3N4O3S
|
1
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| 1 |
Ki = 15 nM
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CP0254479
|
2-{4-[3-(4-Pyrimidin-2-yl-piperazin-1-yl)-propoxy]-phenyl}-1H-benzoimidazole
Show/Hide
|
C24H26N6O
|
1
|
| 1 |
Ki = 15 nM
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CP0454715
|
N-[4-[2-[4-(4-chlorophenyl)piperazin-1-yl]ethyl]cyclohexyl]cyclohexanecarboxamide
Show/Hide
|
C25H38ClN3O
|
1
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| 1 |
Ki = 15 nM
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CP0240250
|
N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]quinolin-2-amine
Show/Hide
|
C24H30N4O
|
1
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| 1 |
Ki = 15 nM
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CP0405815
|
[5-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butoxy]pyrazolo[1,5-a]pyridin-2-yl]methanol
Show/Hide
|
C23H30N4O3
|
1
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| 1 |
Ki = 15 nM
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CP0486723
|
3-[4-[2-[(5R)-7-chloro-5-methyl-1,2,4,5-tetrahydro-3-benzazepin-3-yl]ethyl]cyclohexyl]-1,1-diethylurea
Show/Hide
|
C24H38ClN3O
|
1
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| 1 |
Ki = 15 nM
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CP0171884
|
1-[(2-bromophenyl)methyl]-N-[5-[4-(2-methoxyphenyl)piperazin-1-yl]pentyl]-5-methyltriazole-4-carboxamide
Show/Hide
|
C27H35BrN6O2
|
1
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| 1 |
Ki = 15.14 nM
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CP0471199
|
(E)-N-[4-[4-[bis(2-methoxyphenyl)methyl]piperazin-1-yl]butyl]-3-phenylprop-2-enamide
Show/Hide
|
C32H39N3O3
|
1
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| 1 |
Ki = 15.2 nM
|
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CP0501038
|
N-[4-[4-[bis(2-methoxyphenyl)methyl]piperazin-1-yl]butyl]naphthalene-2-carboxamide
Show/Hide
|
C34H39N3O3
|
1
|
| 1 |
Ki = 15.2 nM
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CP0919279
|
2-Phenyl-cyclopropanecarboxylic acid {4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-butyl}-amide oxalic acid
Show/Hide
|
C27H35N3O6
|
1
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| 1 |
Ki = 15.5 nM
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CP0430894
|
4-methoxy-N-methyl-N-phenyl-3-[5-[[(2S)-2-phenylazepan-1-yl]methyl]-1H-pyrrol-2-yl]benzenesulfonamide
Show/Hide
|
C31H35N3O3S
|
1
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| 1 |
Ki = 15.85 nM
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CP0376420
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N-[4-[(4aR,10bR)-2,3,4a,5,6,10b-hexahydro-1H-benzo[f]quinolin-4-yl]butyl]-4-phenylbenzamide
Show/Hide
|
C30H34N2O
|
1
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| 1 |
Ki = 15.85 nM
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CP0383306
|
N-[4-[(3aS,9bS)-6-methoxy-1,2,3a,4,5,9b-hexahydrobenzo[e]indol-3-yl]butyl]-4-phenylbenzamide
Show/Hide
|
C30H34N2O2
|
1
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| 1 |
Ki = 15.85 nM
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CP0524085
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N-[4-[(3aS,9bS)-1,2,3a,4,5,9b-hexahydrobenzo[e]indol-3-yl]butyl]-4-phenylbenzamide
Show/Hide
|
C29H32N2O
|
1
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| 1 |
Ki = 15.85 nM
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CP0436823
|
2-benzyl-8-chloro-3,3a,4,9b-tetrahydro-1H-chromeno[3,4-c]pyrrole
Show/Hide
|
C18H18ClNO
|
1
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| 1 |
Ki = 15.85 nM
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CP0503585
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(3aS,9bR)-2-[(4-fluorophenyl)methyl]-3,3a,4,9b-tetrahydro-1H-chromeno[3,4-c]pyrrole-8-carbonitrile
Show/Hide
|
C19H17FN2O
|
1
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| 1 |
Ki = 15.85 nM
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CP0528827
|
2-propyl-3,3a,4,9b-tetrahydro-1H-chromeno[3,4-c]pyrrole-8-carbonitrile
Show/Hide
|
C15H18N2O
|
1
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| 1 |
Ki = 15.85 nM
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CP0406382
|
N-[4-[[2-(methylamino)-5,6,7,8-tetrahydroquinazolin-6-yl]-propylamino]butyl]-4-phenylbenzamide
Show/Hide
|
C29H37N5O
|
1
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| 1 |
Ki = 15.85 nM
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CP0508071
|
N-[4-[(2-methylsulfanyl-5,6,7,8-tetrahydroquinazolin-6-yl)-propylamino]butyl]-4-phenylbenzamide
Show/Hide
|
C29H36N4OS
|
1
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| 1 |
Ki = 15.85 nM
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CP0691254
|
1H-Indole-2-carboxylic acid {4-[2-(6-cyano-3,4-dihydro-1H-isoquinolin-2-yl)-ethyl]-cyclohexyl}-amide
Show/Hide
|
C27H31ClN4O
|
1
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| 1 |
Ki = 15.85 nM
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CP0402413
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N-[4-[2-(7-cyano-1,2,4,5-tetrahydro-3-benzazepin-3-yl)ethyl]cyclohexyl]-1H-indole-2-carboxamide
Show/Hide
|
C28H32N4O
|
1
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| 1 |
Ki = 15.85 nM
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CP0311605
|
1-benzyl-N-[5-[4-(2-methoxyphenyl)piperazin-1-yl]pentyl]-5-methyltriazole-4-carboxamide
Show/Hide
|
C27H36N6O2
|
1
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| 1 |
Ki = 15.85 nM
|
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CP0145071
|
4'-chloro-biphenyl-4-sulfonic acid (3-methyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-yl)-amide
Show/Hide
|
C23H23ClN2O2S
|
1
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| 1 |
Ki = 15.85 nM
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CP0157631
|
4-butyl-N-(2,3,4,5-tetrahydro-1H-3-benzazepin-7-yl)benzenesulfonamide
Show/Hide
|
C20H26N2O2S
|
1
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| 1 |
Ki = 15.85 nM
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CP0715637
|
4-(3,5-dimethylisoxazol-4-yl)-N-(3-methyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-yl)benzenesulfonamide
Show/Hide
|
C22H25N3O3S
|
1
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| 1 |
Ki = 15.85 nM
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CP0782774
|
4'-cyano-biphenyl-4-sulfonic acid (3-methyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-yl)-amide
Show/Hide
|
C24H23N3O2S
|
1
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| 1 |
Ki = 15.85 nM
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CP0399508
|
7-(2,5-dimethylpyrazol-3-yl)-3-[2-[[4-methyl-5-(2-methylquinolin-5-yl)-1,2,4-triazol-3-yl]sulfanyl]ethyl]-1,2,4,5-tetrahydro-3-benzazepine
Show/Hide
|
C30H33N7S
|
1
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| 1 |
Ki = 15.85 nM
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CP0399450
|
1-[[5-(5-ethylsulfonyl-2-methoxyphenyl)-1H-pyrrol-2-yl]methyl]azepane
Show/Hide
|
C20H28N2O3S
|
1
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| 1 |
Ki = 15.85 nM
|
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CP0266797
|
5-[3-[2-(1,3-dihydroisoindol-2-yl)ethyl]-2-oxoimidazolidin-1-yl]-2-fluorobenzonitrile
Show/Hide
|
C20H19FN4O
|
1
|
| 1 |
Ki = 15.85 nM
|
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CP0092523
|
1-(3-chlorophenyl)-3-[2-[(1S,5R)-1,8,8-trimethyl-3-azabicyclo[3.2.1]octan-3-yl]ethyl]imidazolidin-2-one
Show/Hide
|
C21H30ClN3O
|
1
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| 1 |
Ki = 15.85 nM
|
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CP0039023
|
5-[5-[3-(6-bromospiro[2,3-dihydro-1H-naphthalene-4,3'-pyrrolidine]-1'-yl)propylsulfanyl]-4-methyl-1,2,4-triazol-3-yl]-4-methyl-1,3-oxazole
Show/Hide
|
C23H28BrN5OS
|
1
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| 1 |
Ki = 15.85 nM
|
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CP0320374
|
5-[4-methyl-5-[3-[2-[4-(trifluoromethyl)phenyl]morpholin-4-yl]propylsulfanyl]-1,2,4-triazol-3-yl]pyridine-2-carboxamide
Show/Hide
|
C23H25F3N6O2S
|
2
|
| 1 |
Ki = 15.85 nM
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| 2 |
Ki > 10000 nM
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CP0366927
|
4-[3-[[4-methyl-5-[4-(5-methyl-1,2,4-oxadiazol-3-yl)phenyl]-1,2,4-triazol-3-yl]sulfanyl]propyl]-2-(4-methylphenyl)morpholine
Show/Hide
|
C26H30N6O2S
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2
|
| 1 |
Ki = 15.85 nM
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| 2 |
Ki > 10000 nM
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CP0878620
|
1-Benzhydryl-4-{4-[3-(2,4-dimethoxy-phenyl)-isoxazol-5-yl]-butyl}-piperazine hydrochloride
Show/Hide
|
C32H38ClN3O3
|
1
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| 1 |
Ki = 16 nM
|
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CP0885775
|
1-{4-[3-(2,4-Dimethoxy-phenyl)-isoxazol-5-yl]-butyl}-4-phenyl-piperazine hydrochloride
Show/Hide
|
C25H32ClN3O3
|
1
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| 1 |
Ki = 16 nM
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CP0393154
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N-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl]-4-fluorobenzenesulfonamide
Show/Hide
|
C20H24Cl2FN3O2S
|
1
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| 1 |
Ki = 16 nM
|
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CP0528847
|
3-Biphenyl-4-yl-N-{4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-butyl}-acrylamide
Show/Hide
|
C30H35N3O2
|
1
|
| 1 |
Ki = 16 nM
|
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CP0378762
|
N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]-12-oxatetracyclo[8.5.2.24,7.011,15]nonadeca-1(15),4,6,10,13,16,18-heptaene-13-carboxamide
Show/Hide
|
C34H39N3O3
|
1
|
| 1 |
Ki = 16 nM
|
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CP0428514
|
4-(2-ethoxyethoxymethyl)-N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]benzamide
Show/Hide
|
C27H39N3O4
|
1
|
| 1 |
Ki = 16 nM
|
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CP0436831
|
N,N-dipropyl-6,7,8,9-tetrahydrobenzo[g][1]benzofuran-8-amine
Show/Hide
|
C18H25NO
|
1
|
| 1 |
Ki = 16.2 nM
|
|
|
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CP0083959
|
4-Phenyl-1-((R)-3-phenyl-cyclohex-3-enylmethyl)-1,2,3,6-tetrahydro-pyridine
Show/Hide
|
C24H27N
|
1
|
| 1 |
Ki = 16.6 nM
|
|
|
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CP0374992
|
4-[4-(4-Chlorophenyl)-4-hydroxypiperidin-1-yl]-1-([2.2]paracyclophan-4-yl)butan-1-one
Show/Hide
|
C31H34ClNO2
|
1
|
| 1 |
Ki = 17 nM
|
|
|
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CP0393750
|
6-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butoxy]pyrazolo[1,5-a]pyridine-3-carbaldehyde
Show/Hide
|
C23H28N4O3
|
1
|
| 1 |
Ki = 17 nM
|
|
|
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CP0486720
|
3-[4-[2-[(5R)-7-chloro-5-methyl-1,2,4,5-tetrahydro-3-benzazepin-3-yl]ethyl]cyclohexyl]-1-methyl-1-phenylurea
Show/Hide
|
C27H36ClN3O
|
1
|
| 1 |
Ki = 17.2 nM
|
|
|
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CP0426288
|
N-[4-[2-[(5R)-7-chloro-5-methyl-1,2,4,5-tetrahydro-3-benzazepin-3-yl]ethyl]cyclohexyl]cyclohexanecarboxamide
Show/Hide
|
C26H39ClN2O
|
1
|
| 1 |
Ki = 17.5 nM
|
|
|
|
CP0526468
|
N-[4-[4-[(4-chlorophenyl)-phenylmethyl]piperazin-1-yl]butyl]-1-benzothiophene-2-carboxamide
Show/Hide
|
C30H32ClN3OS
|
1
|
| 1 |
Ki = 17.7 nM
|
|
|
|
CP0906356
|
1-Phenyl-4-[4-(3-phenyl-isoxazol-5-yl)-butyl]-piperazine hydrochloride
Show/Hide
|
C23H28ClN3O
|
1
|
| 1 |
Ki = 18 nM
|
|
|
|
CP0319242
|
2-(4-{3-[4-(2-Chloro-phenyl)-piperazin-1-yl]-propoxy}-phenyl)-1H-benzoimidazole
Show/Hide
|
C26H27ClN4O
|
1
|
| 1 |
Ki = 18 nM
|
|
|
|
CP0375780
|
N-[3-[4-(2-methylsulfanylphenyl)piperazin-1-yl]propyl]pyrazolo[1,5-a]pyridine-3-carboxamide
Show/Hide
|
C22H27N5OS
|
1
|
| 1 |
Ki = 18 nM
|
|
|
|
CP0401111
|
8-hydroxy-5-[2-[2-[3-methoxy-4-(3-phenylpropoxy)phenyl]ethylamino]ethyl]-1H-quinolin-2-one
Show/Hide
|
C29H32N2O4
|
1
|
| 1 |
Ki = 18 nM
|
|
|
|
CP0511136
|
N-[4-[4-(2-methoxyanilino)piperidin-1-yl]butyl]naphthalene-2-carboxamide
Show/Hide
|
C27H33N3O2
|
1
|
| 1 |
Ki = 18.4 nM
|
|
|
|
CP0455123
|
N,N-diethyl-3-[4-[1-[(E)-4-[2-[4-[3-(4-phenylpiperazin-1-yl)propoxy]phenyl]benzimidazol-1-yl]but-2-enyl]benzimidazol-2-yl]phenoxy]propan-1-amine
Show/Hide
|
C50H57N7O2
|
1
|
| 1 |
Ki = 19 nM
|
|
|
|
CP0874524
|
1-(2-Ethoxy-phenyl)-4-{4-[3-(3-nitro-phenyl)-isoxazol-5-yl]-butyl}-piperazine hydrochloride
Show/Hide
|
C25H31ClN4O4
|
1
|
| 1 |
Ki = 19 nM
|
|
|
|
CP0894585
|
1-Benzhydryl-4-{4-[3-(3-nitro-phenyl)-isoxazol-5-yl]-butyl}-piperazine hydrochloride
Show/Hide
|
C30H33ClN4O3
|
1
|
| 1 |
Ki = 19 nM
|
|
|
|
CP0907030
|
N-(4-{2-[4-(2,3-Dichloro-phenyl)-piperazin-1-yl]-ethyl}-cyclohexyl)-benzamide
Show/Hide
|
C25H31Cl2N3O
|
1
|
| 1 |
Ki = 19 nM
|
|
|
|
CP0036303
|
N-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl]isoquinolin-1-amine
Show/Hide
|
C23H26Cl2N4
|
1
|
| 1 |
Ki = 19 nM
|
|
|
|
CP0489220
|
[4-(4-chlorophenyl)-1-[4-(4-fluorophenyl)-4-oxobutyl]piperidin-4-yl] 3-[1-[2-[2-[2-[2-[2-[4-[3-[4-(4-chlorophenyl)-1-[4-(4-fluorophenyl)-4-oxobutyl]piperidin-4-yl]oxy-3-oxopropyl]triazol-1-yl]ethoxy]ethoxy]ethoxy]ethoxy]ethyl]triazol-4-yl]propanoate
Show/Hide
|
C62H74Cl2F2N8O10
|
1
|
| 1 |
Ki = 19 nM
|
|
|
|
CP0389477
|
(4aR,12bR)-4-propyl-3,4a,5,6,10,12b-hexahydro-2H-isoquinolino[6,7-h][1,4]benzoxazin-11-one
Show/Hide
|
C18H22N2O2
|
1
|
| 1 |
Ki = 19.05 nM
|
|
|
|
CP0436134
|
5-(furan-2-yl)-N-(4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl)-1H-pyrazole-3-carboxamide
Show/Hide
|
C23H29N5O3
|
1
|
| 1 |
Ki = 19.3 nM
|
|
|
|
CP0298050
|
Benzyl-[2-(1H-indol-4-yloxy)-ethyl]-amine
Show/Hide
|
C17H18N2O
|
1
|
| 1 |
Ki = 19.5 nM
|
|
|
|
CP0467111
|
3-(4-Benzyloxy-phenyl)-N-{4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-butyl}-acrylamide
Show/Hide
|
C31H37N3O3
|
1
|
| 1 |
Ki = 19.5 nM
|
|
|
|
CP0897973
|
N-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-3-(3-phenoxy-phenyl)-acrylamide oxalic acid
Show/Hide
|
C32H37N3O7
|
1
|
| 1 |
Ki = 19.5 nM
|
|
|
|
CP0389479
|
S32504
Show/Hide
|
C16H22N2O2
|
1
|
| 1 |
Ki = 19.5 nM
|
|
|
|
CP0430518
|
3-Methyl-thiophene-2-carboxylic acid (4-{2-[4-(2,3-dichloro-phenyl)-piperazin-1-yl]-ethyl}-cyclohexyl)-amide
Show/Hide
|
C24H31Cl2N3OS
|
1
|
| 1 |
Ki = 19.7 nM
|
|
|
|
CP0383964
|
(2R)-5-methoxy-6-(2-phenylethyl)-N,N-dipropyl-1,2,3,4-tetrahydronaphthalen-2-amine
Show/Hide
|
C25H35NO
|
1
|
| 1 |
Ki = 19.95 nM
|
|
|
|
CP0454749
|
2-(3,4-dichlorophenyl)-1-[(6R)-6-(dipropylamino)-1-methoxy-5,6,7,8-tetrahydronaphthalen-2-yl]ethanol
Show/Hide
|
C25H33Cl2NO2
|
1
|
| 1 |
Ki = 19.95 nM
|
|
|
|
CP0442180
|
4-bromo-1-methoxy-N-[2-(4-phenyl-3,6-dihydro-2H-pyridin-1-yl)ethyl]naphthalene-2-carboxamide
Show/Hide
|
C25H25BrN2O2
|
1
|
| 1 |
Ki = 19.95 nM
|
|
|
|
CP0498294
|
N-[4-[[(3aS,9bR)-8-cyano-3,3a,4,9b-tetrahydro-1H-chromeno[3,4-c]pyrrol-2-yl]methyl]phenyl]acetamide
Show/Hide
|
C21H21N3O2
|
1
|
| 1 |
Ki = 19.95 nM
|
|
|
|
CP0384997
|
N-[4-[2-(7-cyano-1,2,4,5-tetrahydro-3-benzazepin-3-yl)ethyl]cyclohexyl]naphthalene-1-carboxamide
Show/Hide
|
C30H33N3O
|
1
|
| 1 |
Ki = 19.95 nM
|
|
|
|
CP0402438
|
CHEMBL86402
Show/Hide
|
C30H33N3O
|
1
|
| 1 |
Ki = 19.95 nM
|
|
|
|
CP0125988
|
N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]pyrazolo[1,5-a]pyridine-4-carboxamide
Show/Hide
|
C23H29N5O2
|
1
|
| 1 |
Ki = 19.95 nM
|
|
|
|
CP0708810
|
4-butyl-N-(2-methylisoindolin-5-yl)benzenesulfonamide
Show/Hide
|
C19H24N2O2S
|
1
|
| 1 |
Ki = 19.95 nM
|
|
|
|
CP0466074
|
CHEMBL2113358
Show/Hide
|
C30H38ClN3O4S
|
1
|
| 1 |
Ki = 19.95 nM
|
|
|
|
CP0045063
|
2-methyl-4-(4-methylpiperazin-1-yl)-10H-thieno[2,3-b][1,5]benzodiazepine
Show/Hide
|
C17H20N4S
|
1
|
| 1 |
Ki = 19.95 nM
|
|
|
|
CP0430311
|
2-(5-ethylsulfonyl-2-methoxyphenyl)-5-(1-pyrrolidin-1-ylethyl)-1H-pyrrole
Show/Hide
|
C19H26N2O3S
|
1
|
| 1 |
Ki = 19.95 nM
|
|
|
|
CP0439701
|
1-[1-[5-(5-ethylsulfonyl-2-methoxyphenyl)-1H-pyrrol-2-yl]ethyl]azepane
Show/Hide
|
C21H30N2O3S
|
1
|
| 1 |
Ki = 19.95 nM
|
|
|
|
CP0497023
|
1-[[5-(5-ethylsulfonyl-2-methoxyphenyl)-1H-pyrrol-2-yl]methyl]-2-phenylazocane
Show/Hide
|
C27H34N2O3S
|
1
|
| 1 |
Ki = 19.95 nM
|
|
|
|
CP0285289
|
1-(3-chloro-4-fluorophenyl)-3-[2-(1,3-dihydroisoindol-2-yl)ethyl]imidazolidin-2-one
Show/Hide
|
C19H19ClFN3O
|
1
|
| 1 |
Ki = 19.95 nM
|
|
|
|
CP0048845
|
1-(3-chlorophenyl)-3-[2-[(1R,5S)-1-methyl-3-phenyl-6-azabicyclo[3.2.1]octan-6-yl]ethyl]imidazolidin-2-one
Show/Hide
|
C25H30ClN3O
|
1
|
| 1 |
Ki = 19.95 nM
|
|
|
|
CP0071120
|
1-[2-[(7,7-dimethyl-1-bicyclo[2.2.1]heptanyl)methyl-methylamino]ethyl]-3-(3-methylphenyl)imidazolidin-2-one
Show/Hide
|
C23H35N3O
|
1
|
| 1 |
Ki = 19.95 nM
|
|
|
|
CP0324091
|
1-[4-[4-methyl-5-[3-[2-[4-(trifluoromethyl)phenyl]morpholin-4-yl]propylsulfanyl]-1,2,4-triazol-3-yl]phenyl]ethanone
Show/Hide
|
C25H27F3N4O2S
|
2
|
| 1 |
Ki = 19.95 nM
|
|
|
| 2 |
Ki > 10000 nM
|
|
|
|
CP0369180
|
4-[3-[(5-cyclohexyl-4-methyl-1,2,4-triazol-3-yl)sulfanyl]propyl]-2-[4-(trifluoromethyl)phenyl]morpholine
Show/Hide
|
C23H31F3N4OS
|
2
|
| 1 |
Ki = 19.95 nM
|
|
|
| 2 |
Ki > 10000 nM
|
|
|
|
CP0878622
|
1-Benzhydryl-4-{4-[3-(3,4-dimethoxy-phenyl)-isoxazol-5-yl]-butyl}-piperazine hydrochloride
Show/Hide
|
C32H38ClN3O3
|
1
|
| 1 |
Ki = 20 nM
|
|
|
|
CP0897133
|
1-{4-[3-(3,4-Dimethoxy-phenyl)-isoxazol-5-yl]-butyl}-4-(2-fluoro-phenyl)-piperazine hydrochloride
Show/Hide
|
C25H31ClFN3O3
|
1
|
| 1 |
Ki = 20 nM
|
|
|
|
CP0461950
|
(S)-1-(bis(4-fluorophenyl)methyl)-4-(3-(3-(3,4-dimethoxyphenyl)-4,5-dihydroisoxazol-5-yl)propyl)piperazine
Show/Hide
|
C31H35F2N3O3
|
1
|
| 1 |
Ki = 20 nM
|
|
|
|
CP0380811
|
4-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy]pyrazolo[1,5-a]pyridine-3-carbaldehyde
Show/Hide
|
C22H24Cl2N4O2
|
1
|
| 1 |
Ki = 20 nM
|
|
|
|
CP0393752
|
5-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butoxy]pyrazolo[1,5-a]pyridine
Show/Hide
|
C22H28N4O2
|
1
|
| 1 |
Ki = 20 nM
|
|
|
|
CP0502521
|
N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]-4-phenylcyclohexane-1-carboxamide
Show/Hide
|
C28H39N3O2
|
1
|
| 1 |
Ki = 20.6 nM
|
|
|
|
CP0380641
|
4-methyl-5-[4-methyl-5-[4-[(2R,3S)-2-[4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptan-5-yl]butylsulfanyl]-1,2,4-triazol-3-yl]-1,3-oxazole
Show/Hide
|
C24H28F3N5OS
|
1
|
| 1 |
Ki = 21.38 nM
|
|
|
|
CP0391644
|
5-(furan-2-yl)-N-[4-[4-(5-methoxy-1,2-benzoxazol-3-yl)piperazin-1-yl]butyl]-1H-pyrazole-3-carboxamide
Show/Hide
|
C24H28N6O4
|
1
|
| 1 |
Ki = 21.4 nM
|
|
|
|
CP0400133
|
N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]-3-(2-phenylethynyl)benzamide
Show/Hide
|
C30H33N3O2
|
1
|
| 1 |
Ki = 22 nM
|
|
|
|
CP0433256
|
5-bromo-2-methoxy-N-[[(2S)-1-prop-2-enylpyrrolidin-2-yl]methyl]benzamide
Show/Hide
|
C16H21BrN2O2
|
1
|
| 1 |
Ki = 22 nM
|
|
|
|
CP0487364
|
Adamantane-1-carboxylic acid (4-{2-[4-(2,3-dichloro-phenyl)-piperazin-1-yl]-ethyl}-cyclohexyl)-amide
Show/Hide
|
C29H41Cl2N3O
|
1
|
| 1 |
Ki = 22 nM
|
|
|
|
CP0497502
|
4-imidazol-1-yl-N-[4-[4-(5-methoxy-1,2-benzoxazol-3-yl)piperazin-1-yl]butyl]benzamide
Show/Hide
|
C26H30N6O3
|
1
|
| 1 |
Ki = 22.6 nM
|
|
|
|
CP0509473
|
N-[4-[4-[bis(2-methoxyphenyl)methyl]piperazin-1-yl]butyl]-1-benzothiophene-2-carboxamide
Show/Hide
|
C32H37N3O3S
|
1
|
| 1 |
Ki = 22.8 nM
|
|
|
|
CP0527903
|
N-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl]-4-phenylcyclohexane-1-carboxamide
Show/Hide
|
C27H35Cl2N3O
|
1
|
| 1 |
Ki = 22.8 nM
|
|
|
|
CP0916903
|
1-((S)-7-Dipropylamino-5,6,7,8-tetrahydro-indolizin-3-yl)-2,2,2-trifluoro-ethanone
Show/Hide
|
C16H23F3N2O
|
1
|
| 1 |
Ki = 22.91 nM
|
|
|
|
CP0900185
|
1-{4-[3-(4-Fluoro-phenyl)-isoxazol-5-yl]-butyl}-4-(2-methoxy-phenyl)-piperazine hydrochloride
Show/Hide
|
C24H29ClFN3O2
|
1
|
| 1 |
Ki = 23 nM
|
|
|
|
CP0036302
|
N-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl]quinolin-2-amine
Show/Hide
|
C23H26Cl2N4
|
1
|
| 1 |
Ki = 23 nM
|
|
|
|
CP0418547
|
2-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-benzo[f]isoindole-1,3-dione
Show/Hide
|
C27H29N3O3
|
1
|
| 1 |
Ki = 23.3 nM
|
|
|
|
CP0515940
|
N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]-4-morpholin-4-ylbenzamide
Show/Hide
|
C26H36N4O3
|
1
|
| 1 |
Ki = 23.9 nM
|
|
|
|
CP0077378
|
4-[4-(4-Phenyl-3,6-dihydro-2H-pyridin-1-yl)-but-1-ynyl]-phenylamine
Show/Hide
|
C21H22N2
|
1
|
| 1 |
Ki = 24 nM
|
|
|
|
CP0897086
|
1-{4-[3-(3,4-Dimethoxy-phenyl)-isoxazol-5-yl]-butyl}-4-phenyl-piperazine hydrochloride
Show/Hide
|
C25H32ClN3O3
|
1
|
| 1 |
Ki = 24 nM
|
|
|
|
CP0373005
|
5-Methyl-thiophene-2-carboxylic acid (4-{2-[4-(2,3-dichloro-phenyl)-piperazin-1-yl]-ethyl}-cyclohexyl)-amide
Show/Hide
|
C24H31Cl2N3OS
|
1
|
| 1 |
Ki = 24 nM
|
|
|
|
CP0437282
|
5-[4-[4-(5-hydroxy-2,3-dihydro-1,4-benzodioxin-8-yl)piperazin-1-yl]butoxy]pyrazolo[1,5-a]pyridine-3-carbaldehyde
Show/Hide
|
C24H28N4O5
|
1
|
| 1 |
Ki = 24 nM
|
|
|
|
CP0392502
|
2-[2-(4-Styryl-3,6-dihydro-2H-pyridin-1-yl)-ethyl]-1H-pyrrolo[2,3-b]pyridine
Show/Hide
|
C22H23N3
|
1
|
| 1 |
Ki = 25 nM
|
|
|
|
CP0935452
|
Thiophene-2-carboxylic acid {4-[2-(4-phenyl-piperazin-1-yl)-ethyl]-cyclohexyl}-amide
Show/Hide
|
C23H31N3OS
|
1
|
| 1 |
Ki = 25 nM
|
|
|
|
CP0277803
|
N-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl]pyridin-2-amine
Show/Hide
|
C19H24Cl2N4
|
1
|
| 1 |
Ki = 25 nM
|
|
|
|
CP0399135
|
4-[2-[2-(2-methoxyphenoxy)ethylamino]ethyl]benzene-1,2-diol
Show/Hide
|
C17H21NO4
|
1
|
| 1 |
Ki = 25 nM
|
|
|
|
CP0438120
|
1-(N-benzyl-4-fluoroanilino)-3-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]urea
Show/Hide
|
C28H34FN5O2
|
1
|
| 1 |
Ki = 25 nM
|
|
|
|
CP0376476
|
1-[[6-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-2-yl]methyl]-1-(4-methoxyphenyl)urea
Show/Hide
|
C25H35N3O2
|
1
|
| 1 |
Ki = 25.12 nM
|
|
|
|
CP0454598
|
2-(4-chlorophenyl)-1-[(5S,6R)-6-(dipropylamino)-1-methoxy-5-methyl-5,6,7,8-tetrahydronaphthalen-2-yl]ethanol
Show/Hide
|
C26H36ClNO2
|
1
|
| 1 |
Ki = 25.12 nM
|
|
|
|
CP0463784
|
(4aR,11bR)-4-propyl-2,3,4a,5,6,8,9,11b-octahydro-1H-[1]benzofuro[6,5-f]quinoline
Show/Hide
|
C18H25NO
|
1
|
| 1 |
Ki = 25.12 nM
|
|
|
|
CP0471100
|
4-Bromo-1-methoxy-naphthalene-2-carboxylic acid [2-(4-phenyl-piperazin-1-yl)-ethyl]-amide
Show/Hide
|
C24H26BrN3O2
|
1
|
| 1 |
Ki = 25.12 nM
|
|
|
|
CP0518291
|
2-benzyl-3,3a,4,9b-tetrahydro-1H-chromeno[3,4-c]pyrrole-7-carbonitrile
Show/Hide
|
C19H18N2O
|
1
|
| 1 |
Ki = 25.12 nM
|
|
|
|
CP0391260
|
(4aS,10bR)-4-propyl-3,4a,5,10b-tetrahydro-1H-chromeno[3,4-d][1,3]oxazin-9-ol
Show/Hide
|
C14H19NO3
|
1
|
| 1 |
Ki = 25.12 nM
|
|
|
|
CP0408776
|
N-[4-[[2-(dimethylamino)-5,6,7,8-tetrahydroquinazolin-6-yl]-propylamino]butyl]-4-phenylbenzamide
Show/Hide
|
C30H39N5O
|
1
|
| 1 |
Ki = 25.12 nM
|
|
|
|
CP0509143
|
N-[4-(3,4-dihydro-1H-isoquinolin-2-yl)butyl]-4-phenylbenzamide
Show/Hide
|
C26H28N2O
|
1
|
| 1 |
Ki = 25.12 nM
|
|
|
|
CP0506623
|
N-[4-[2-(7-cyano-1,2,4,5-tetrahydro-3-benzazepin-3-yl)ethyl]cyclohexyl]quinoline-4-carboxamide
Show/Hide
|
C29H32N4O
|
1
|
| 1 |
Ki = 25.12 nM
|
|
|
|
CP0449273
|
N-[4-[2-(5-cyano-1,3-dihydroisoindol-2-yl)ethyl]cyclohexyl]-1H-indole-2-carboxamide
Show/Hide
|
C26H28N4O
|
1
|
| 1 |
Ki = 25.12 nM
|
|
|
|
CP0656166
|
N-(3-methyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-yl)-4-(5-methylthiophen-2-yl)benzenesulfonamide
Show/Hide
|
C22H24N2O2S2
|
1
|
| 1 |
Ki = 25.12 nM
|
|
|
|
CP0704117
|
4-butyl-N-(2-methyl-1,2,3,4-tetrahydroisoquinolin-7-yl)benzenesulfonamide
Show/Hide
|
C20H26N2O2S
|
1
|
| 1 |
Ki = 25.12 nM
|
|
|
|
CP0372578
|
5-methyl-3-[3-[3-[(4-methyl-5-pyridin-4-yl-1,2,4-triazol-3-yl)sulfanyl]propyl]-1,2,4,5-tetrahydro-3-benzazepin-7-yl]-1,2-oxazole
Show/Hide
|
C25H28N6OS
|
1
|
| 1 |
Ki = 25.12 nM
|
|
|
|
CP0497020
|
1-[[5-(5-ethylsulfonyl-2-methoxyphenyl)-1H-pyrrol-2-yl]methyl]piperidine
Show/Hide
|
C19H26N2O3S
|
1
|
| 1 |
Ki = 25.12 nM
|
|
|
|
CP0226493
|
1-(3-chlorophenyl)-3-[2-[(1S,7R)-10,10-dimethyl-4-azatricyclo[5.2.1.01,5]decan-4-yl]ethyl]imidazolidin-2-one
Show/Hide
|
C22H30ClN3O
|
1
|
| 1 |
Ki = 25.12 nM
|
|
|
|
CP0356485
|
CHEMBL564948
Show/Hide
|
C23H35N3O
|
1
|
| 1 |
Ki = 25.12 nM
|
|
|
|
CP0760707
|
5-(5-(3-(1-(3-fluoro-5-(trifluoromethyl)phenyl)-3-azabicyclo[3.1.0]hexan-3-yl)propylthio)-4-methyl-4H-1,2,4-triazol-3-yl)-4-methyloxazole hydrochloride
Show/Hide
|
C22H24ClF4N5OS
|
1
|
| 1 |
Ki = 25.12 nM
|
|
|
|
CP0197727
|
4-[3-[[4-methyl-5-(4-methyl-1,3-oxazol-5-yl)-1,2,4-triazol-3-yl]sulfanyl]propyl]-2-[4-(trifluoromethyl)phenyl]morpholine
Show/Hide
|
C21H24F3N5O2S
|
2
|
| 1 |
Ki = 25.12 nM
|
|
|
| 2 |
Ki > 10000 nM
|
|
|
|
CP0525144
|
7-methoxy-N-(4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl)benzofuran-2-carboxamide
Show/Hide
|
C25H31N3O4
|
1
|
| 1 |
Ki = 25.5 nM
|
|
|
|
CP0407019
|
N,N-diethyl-3-[4-[1-[(E)-4-[2-(4-methoxyphenyl)benzimidazol-1-yl]but-2-enyl]benzimidazol-2-yl]phenoxy]propan-1-amine
Show/Hide
|
C38H41N5O2
|
1
|
| 1 |
Ki = 26 nM
|
|
|
|
CP0429840
|
((6S,7R)-6-Methyl-6,7,8,9-tetrahydro-naphtho[1,2-b]furan-7-yl)-dipropyl-amine
Show/Hide
|
C19H27NO
|
1
|
| 1 |
Ki = 27 nM
|
|
|
|
CP0938102
|
1-Phenyl-4-[4-(3-styryl-isoxazol-5-yl)-butyl]-piperazine hydrochloride
Show/Hide
|
C25H30ClN3O
|
1
|
| 1 |
Ki = 27 nM
|
|
|
|
CP0025100
|
4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-methoxy-benzamide;hydrochloride
Show/Hide
|
C14H22ClN3O2
|
1
|
| 1 |
Ki = 27 nM
|
|
|
|
CP0153919
|
2-(4-{3-[4-(4-Chloro-phenyl)-piperazin-1-yl]-propoxy}-phenyl)-1H-benzoimidazole
Show/Hide
|
C26H27ClN4O
|
1
|
| 1 |
Ki = 27 nM
|
|
|
|
CP0411984
|
4-[4-(2,5-Dimethylphenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one
Show/Hide
|
C23H28FNO2
|
1
|
| 1 |
Ki = 27 nM
|
|
|
|
CP0393917
|
7-[4-[4-(8-hydroxyquinolin-5-yl)piperazin-1-yl]butoxy]-3,4-dihydro-1H-quinolin-2-one
Show/Hide
|
C26H30N4O3
|
1
|
| 1 |
Ki = 27 nM
|
|
|
|
CP0480414
|
N-[2-chloro-5-[2-(thiophen-2-ylmethylamino)ethoxy]phenyl]methanesulfonamide
Show/Hide
|
C14H17ClN2O3S2
|
1
|
| 1 |
Ki = 27.8 nM
|
|
|
|
CP0497537
|
(3-{4-[1-(4-{2-[4-(3-Diethylamino-propoxy)-phenyl]-benzoimidazol-1-yl}-butyl)-1H-benzoimidazol-2-yl]-phenoxy}-propyl)-diethyl-amine
Show/Hide
|
C44H56N6O2
|
1
|
| 1 |
Ki = 28 nM
|
|
|
|
CP0427968
|
2-[4-[4-[(4-chlorophenyl)-phenylmethyl]piperazin-1-yl]butyl]isoindole-1,3-dione
Show/Hide
|
C29H30ClN3O2
|
1
|
| 1 |
Ki = 28 nM
|
|
|
|
CP0375516
|
1-Benzyl-4-(3-methyl-4-phenyl-pyrazol-1-yl)-piperidine
Show/Hide
|
C22H25N3
|
1
|
| 1 |
Ki = 28 nM
|
|
|
|
CP0475764
|
N-[4-[4-(2,5-dimethylphenyl)piperazin-1-yl]butyl]-2,5-dimethylbenzamide
Show/Hide
|
C25H35N3O
|
1
|
| 1 |
Ki = 28 nM
|
|
|
|
CP0408071
|
N-(3-cyanopyrazolo[1,5-a]pyridin-5-yl)-4-[4-(2-methoxyphenyl)piperazin-1-yl]butanamide
Show/Hide
|
C23H26N6O2
|
1
|
| 1 |
Ki = 28 nM
|
|
|
|
CP0435207
|
N-[4-(4-benzhydrylpiperazin-1-yl)butyl]thiophene-2-carboxamide
Show/Hide
|
C26H31N3OS
|
1
|
| 1 |
Ki = 28.4 nM
|
|
|
|
CP0113655
|
N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]pyrazolo[1,5-a]pyridine-7-carboxamide
Show/Hide
|
C23H29N5O2
|
1
|
| 1 |
Ki = 28.84 nM
|
|
|
|
CP0172633
|
1-[(4-methoxyphenyl)methyl]-N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]-5-methyltriazole-4-carboxamide
Show/Hide
|
C27H36N6O3
|
1
|
| 1 |
Ki = 28.84 nM
|
|
|
|
CP0073485
|
1-benzyl-4-(3-hydroxyphenyl)piperazine
Show/Hide
|
C17H20N2O
|
1
|
| 1 |
Ki = 28.9 nM
|
|
|
|
CP0393062
|
N-[2-[4-(2,3-dichlorophenyl)piperazin-1-yl]ethyl]-4-(2-phenylethynyl)benzamide
Show/Hide
|
C27H25Cl2N3O
|
1
|
| 1 |
Ki = 29 nM
|
|
|
|
CP0500976
|
2-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-benzo[de]isoquinoline-1,3-dione
Show/Hide
|
C27H29N3O3
|
1
|
| 1 |
Ki = 29 nM
|
|
|
|
CP0900199
|
1-Benzhydryl-4-{4-[3-(4-fluoro-phenyl)-isoxazol-5-yl]-butyl}-piperazine hydrochloride
Show/Hide
|
C30H33ClFN3O
|
1
|
| 1 |
Ki = 30 nM
|
|
|
|
CP0371912
|
2-(4-(4-phenyl-1-piperazinyl)butyl)-1-isoindolinone
Show/Hide
|
C23H29N3O2
|
1
|
| 1 |
Ki = 30 nM
|
|
|
|
CP0483750
|
[4-(4-chlorophenyl)-1-[4-(4-fluorophenyl)-4-oxobutyl]piperidin-4-yl] 3-(dimethylamino)propanoate
Show/Hide
|
C26H32ClFN2O3
|
1
|
| 1 |
Ki = 30 nM
|
|
|
|
CP0426894
|
N-[4-(4-benzhydrylpiperazin-1-yl)butyl]cyclohexanecarboxamide
Show/Hide
|
C28H39N3O
|
1
|
| 1 |
Ki = 30.2 nM
|
|
|
|
CP0477826
|
N-[4-(4-benzhydrylpiperazin-1-yl)butyl]-1-benzothiophene-2-carboxamide
Show/Hide
|
C30H33N3OS
|
1
|
| 1 |
Ki = 30.3 nM
|
|
|
|
CP0913768
|
(S)-7-Dipropylamino-5,6,7,8-tetrahydro-indolizine-3-carbaldehyde oxime
Show/Hide
|
C15H25N3O
|
1
|
| 1 |
Ki = 30.9 nM
|
|
|
|
CP0373347
|
N-[2-[4-(2,3-dichlorophenyl)piperazin-1-yl]ethyl]-4-ethynylbenzamide
Show/Hide
|
C21H21Cl2N3O
|
1
|
| 1 |
Ki = 31 nM
|
|
|
|
CP0374760
|
1-[[3-methoxy-4-[[1-[8-[4-[[2-methoxy-4-[[4-(2-methoxyphenyl)piperazin-1-yl]methyl]phenoxy]methyl]triazol-1-yl]octyl]triazol-4-yl]methoxy]phenyl]methyl]-4-(2-methoxyphenyl)piperazine
Show/Hide
|
C52H68N10O6
|
1
|
| 1 |
Ki = 31 nM
|
|
|
|
CP0489217
|
bis[4-(4-chlorophenyl)-1-[4-(4-fluorophenyl)-4-oxobutyl]piperidin-4-yl] pentanedioate
Show/Hide
|
C47H50Cl2F2N2O6
|
1
|
| 1 |
Ki = 31 nM
|
|
|
|
CP0454989
|
N-[4-[4-(N-benzylanilino)piperidin-1-yl]butyl]-1-benzothiophene-2-carboxamide
Show/Hide
|
C31H35N3OS
|
1
|
| 1 |
Ki = 31.1 nM
|
|
|
|
CP0464470
|
2-[[5-(5-ethylsulfonyl-2-methoxyphenyl)-1H-pyrrol-2-yl]methyl]-3,4-dihydro-1H-isoquinoline
Show/Hide
|
C23H26N2O3S
|
1
|
| 1 |
Ki = 31.62 nM
|
|
|
|
CP0086945
|
1-[2-[1-benzothiophen-2-ylmethyl(methyl)amino]ethyl]-3-(3-chlorophenyl)imidazolidin-2-one
Show/Hide
|
C21H22ClN3OS
|
1
|
| 1 |
Ki = 31.62 nM
|
|
|
|
CP0308489
|
4-methyl-5-[4-methyl-5-[3-[1-[2-(trifluoromethyl)phenyl]-3-azabicyclo[3.1.0]hexan-3-yl]propylsulfanyl]-1,2,4-triazol-3-yl]-1,3-oxazole
Show/Hide
|
C22H24F3N5OS
|
1
|
| 1 |
Ki = 31.62 nM
|
|
|
|
CP0362591
|
4-[3-[3-[[4-methyl-5-(2-methylquinolin-5-yl)-1,2,4-triazol-3-yl]sulfanyl]propyl]-3-azabicyclo[3.1.0]hexan-1-yl]benzonitrile
Show/Hide
|
C28H28N6S
|
1
|
| 1 |
Ki = 31.62 nM
|
|
|
|
CP0039126
|
5-[5-[3-(6-methoxyspiro[2,3-dihydro-1H-naphthalene-4,3'-pyrrolidine]-1'-yl)propylsulfanyl]-4-methyl-1,2,4-triazol-3-yl]-4-methyl-1,3-oxazole
Show/Hide
|
C24H31N5O2S
|
1
|
| 1 |
Ki = 31.62 nM
|
|
|
|
CP0039127
|
5-[5-[3-(5-chlorospiro[1,2-dihydroindene-3,3'-pyrrolidine]-1'-yl)propylsulfanyl]-4-methyl-1,2,4-triazol-3-yl]-2,4-dimethyl-1,3-thiazole
Show/Hide
|
C23H28ClN5S2
|
1
|
| 1 |
Ki = 31.62 nM
|
|
|
|
CP0105805
|
5-[5-[3-(6-chlorospiro[1,2-dihydroindene-3,3'-pyrrolidine]-1'-yl)propylsulfanyl]-4-methyl-1,2,4-triazol-3-yl]-2,4-dimethyl-1,3-thiazole
Show/Hide
|
C23H28ClN5S2
|
1
|
| 1 |
Ki = 31.62 nM
|
|
|
|
CP0790987
|
5-[2-Fluoro-4-(trifluoromethyl)phenyl]bicyclo[3.1.0]hex-2-yl}-(3-{[4-methyl-5-(4-methyl-1,3-oxazol-5-yl)-4H-1,2,4-triazol-3-yl]-thio}propyl)amine
Show/Hide
|
C23H26ClF4N5OS
|
1
|
| 1 |
Ki = 31.62 nM
|
|
|
|
CP0846660
|
N-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-2-naphthalen-2-yl-acetamide oxalic acid
Show/Hide
|
C29H35N3O6
|
1
|
| 1 |
Ki = 32 nM
|
|
|
|
CP0430525
|
4-Methyl-thiophene-2-carboxylic acid (4-{2-[4-(2,3-dichloro-phenyl)-piperazin-1-yl]-ethyl}-cyclohexyl)-amide
Show/Hide
|
C24H31Cl2N3OS
|
1
|
| 1 |
Ki = 32 nM
|
|
|
|
CP0413705
|
5-[4-[2-[4-(2,3-dichlorophenyl)piperazin-1-yl]ethyl]triazol-1-yl]pyrazolo[1,5-a]pyridine-3-carbaldehyde
Show/Hide
|
C22H21Cl2N7O
|
1
|
| 1 |
Ki = 32 nM
|
|
|
|
CP0430225
|
7-[5-methoxy-3-(1,2,3,6-tetrahydropyridin-4-yl)indol-1-yl]sulfonylquinoline
Show/Hide
|
C23H21N3O3S
|
1
|
| 1 |
Ki = 32 nM
|
|
|
|
CP0160175
|
1-[(2-bromophenyl)methyl]-N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]-5-methyltriazole-4-carboxamide
Show/Hide
|
C26H33BrN6O2
|
1
|
| 1 |
Ki = 32.36 nM
|
|
|
|
CP0510649
|
N-[4-(4-benzhydryl-1,4-diazepan-1-yl)butyl]naphthalene-2-carboxamide
Show/Hide
|
C33H37N3O
|
1
|
| 1 |
Ki = 32.6 nM
|
|
|
|
CP0498244
|
N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]naphthalene-1-carboxamide
Show/Hide
|
C26H31N3O2
|
1
|
| 1 |
Ki = 32.6 nM
|
|
|
|
CP0433257
|
5-(3-fluoropropyl)-2-methoxy-N-[[(2S)-1-prop-2-enylpyrrolidin-2-yl]methyl]benzamide
Show/Hide
|
C19H27FN2O2
|
1
|
| 1 |
Ki = 33 nM
|
|
|
|
CP0391962
|
1-(2-methoxyphenyl)-4-[[3-[[4-(2-methoxyphenyl)piperazin-1-yl]methyl]azulen-1-yl]methyl]piperazine
Show/Hide
|
C34H40N4O2
|
1
|
| 1 |
Ki = 33 nM
|
|
|
|
CP0717121
|
4-phenyl-1-((1-phenyl-1H-pyrazol-4-yl)methyl)piperidine
Show/Hide
|
C21H23N3
|
1
|
| 1 |
Ki = 33.11 nM
|
|
|
|
CP0172632
|
N-[5-[4-(2,3-dichlorophenyl)piperazin-1-yl]pentyl]-1-[(4-methoxyphenyl)methyl]-5-methyltriazole-4-carboxamide
Show/Hide
|
C27H34Cl2N6O2
|
1
|
| 1 |
Ki = 33.88 nM
|
|
|
|
CP0272971
|
Benzyl-[(R)-1-(2,3,4,7-tetrahydro-pyrano[2,3-e]indol-2-yl)methyl]-amine
Show/Hide
|
C19H20N2O
|
1
|
| 1 |
Ki = 34 nM
|
|
|
|
CP0405190
|
(3-{4-[1-((E)-4-{2-[4-(3-Diethylamino-propoxy)-phenyl]-benzoimidazol-1-yl}-but-2-enyl)-1H-benzoimidazol-2-yl]-phenoxy}-propyl)-diethyl-amine
Show/Hide
|
C44H54N6O2
|
1
|
| 1 |
Ki = 35 nM
|
|
|
|
CP0458947
|
4-(4-Benzyl-piperazin-1-yl)-1H-indole
Show/Hide
|
C19H21N3
|
1
|
| 1 |
Ki = 35.4 nM
|
|
|
|
CP0371906
|
2-(4-(4-(2-methoxyphenyl)-1-piperazinyl)butyl)-1-isoindolinone
Show/Hide
|
C22H27N3O
|
1
|
| 1 |
Ki = 35.8 nM
|
|
|
|
CP0374763
|
1-[[3-methoxy-4-[[1-[2-[2-[2-[4-[[2-methoxy-4-[[4-(2-methoxyphenyl)piperazin-1-yl]methyl]phenoxy]methyl]triazol-1-yl]ethoxy]ethoxy]ethyl]triazol-4-yl]methoxy]phenyl]methyl]-4-(2-methoxyphenyl)piperazine
Show/Hide
|
C50H64N10O8
|
1
|
| 1 |
Ki = 36 nM
|
|
|
|
CP0426890
|
N-[4-(4-benzhydryl-1,4-diazepan-1-yl)butyl]-1-benzothiophene-2-carboxamide
Show/Hide
|
C31H35N3OS
|
1
|
| 1 |
Ki = 36.9 nM
|
|
|
|
CP0400130
|
N-[5-[4-(2-methoxyphenyl)piperazin-1-yl]pentyl]-3-(2-phenylethynyl)benzamide
Show/Hide
|
C31H35N3O2
|
1
|
| 1 |
Ki = 37 nM
|
|
|
|
CP0935376
|
Naphthalene-2-carboxylic acid {5-[4-(2-methoxy-phenyl)-piperazin-1-yl]-octahydro-pentalen-2-yl}-amide oxalic acid
Show/Hide
|
C32H37N3O6
|
1
|
| 1 |
Ki = 37.2 nM
|
|
|
|
CP0897087
|
1-{4-[3-(3,4-Dimethoxy-phenyl)-isoxazol-5-yl]-butyl}-4-o-tolyl-piperazine hydrochloride
Show/Hide
|
C26H34ClN3O3
|
1
|
| 1 |
Ki = 38 nM
|
|
|
|
CP0880912
|
2-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-isoindole-1,3-dione oxalic acid
Show/Hide
|
C25H29N3O7
|
1
|
| 1 |
Ki = 38 nM
|
|
|
|
CP0452998
|
N-[4-[4-(5-methoxy-1,2-benzoxazol-3-yl)piperazin-1-yl]butyl]-4-morpholin-4-ylbenzamide
Show/Hide
|
C27H35N5O4
|
1
|
| 1 |
Ki = 38 nM
|
|
|
|
CP0472713
|
4-[4-([2.2]Paracyclophan-4-yl)-4-hydroxypiperidin-1-yl]-1-([2.2]-paracyclophan-4-yl)butan-1-one
Show/Hide
|
C41H45NO2
|
1
|
| 1 |
Ki = 38 nM
|
|
|
|
CP0393898
|
7-[4-[4-(5-hydroxy-2,3-dihydro-1,4-benzodioxin-8-yl)piperazin-1-yl]butoxy]-3,4-dihydro-1H-quinolin-2-one
Show/Hide
|
C25H31N3O5
|
1
|
| 1 |
Ki = 38 nM
|
|
|
|
CP0513756
|
N-[4-[4-[(4-chlorophenyl)-phenylmethyl]piperazin-1-yl]butyl]thiophene-2-carboxamide
Show/Hide
|
C26H30ClN3OS
|
1
|
| 1 |
Ki = 38.9 nM
|
|
|
|
CP0916630
|
(S)-5-Dipropylamino-4,5,6,7-tetrahydro-indole-1-carbaldehyde
Show/Hide
|
C15H24N2O
|
1
|
| 1 |
Ki = 38.9 nM
|
|
|
|
CP0442129
|
(3-{4-[1-((E)-4-{2-[4-(3-Cyclohexyl-propoxy)-phenyl]-benzoimidazol-1-yl}-but-2-enyl)-1H-benzoimidazol-2-yl]-phenoxy}-propyl)-diethyl-amine
Show/Hide
|
C46H55N5O2
|
1
|
| 1 |
Ki = 39 nM
|
|
|
|
CP0503155
|
N-[4-[(3-formyl-4,5,6,7-tetrahydropyrazolo[1,5-a]pyridin-5-yl)-propylamino]butyl]-4-phenylbenzamide
Show/Hide
|
C28H34N4O2
|
1
|
| 1 |
Ki = 39 nM
|
|
|
|
CP0385668
|
bis[4-(4-chlorophenyl)-1-[4-(4-fluorophenyl)-4-oxobutyl]piperidin-4-yl] decanedioate
Show/Hide
|
C52H60Cl2F2N2O6
|
1
|
| 1 |
Ki = 39 nM
|
|
|
|
CP0409787
|
4-methoxy-3-[5-[(2-phenylazepan-1-yl)methyl]-1H-pyrrol-2-yl]benzenesulfonamide
Show/Hide
|
C24H29N3O3S
|
1
|
| 1 |
Ki = 39.81 nM
|
|
|
|
CP0458851
|
4-Bromo-1-methoxy-naphthalene-2-carboxylic acid {2-[4-(2-chloro-phenyl)-piperazin-1-yl]-ethyl}-amide
Show/Hide
|
C24H25BrClN3O2
|
1
|
| 1 |
Ki = 39.81 nM
|
|
|
|
CP0498321
|
4-Bromo-1-methoxy-naphthalene-2-carboxylic acid {2-[4-(3-chloro-phenyl)-piperazin-1-yl]-ethyl}-amide
Show/Hide
|
C24H25BrClN3O2
|
1
|
| 1 |
Ki = 39.81 nM
|
|
|
|
CP0502789
|
4-chloro-N-[2-[4-(2,3-dichlorophenyl)piperazin-1-yl]ethyl]-1-methoxynaphthalene-2-carboxamide
Show/Hide
|
C24H24Cl3N3O2
|
1
|
| 1 |
Ki = 39.81 nM
|
|
|
|
CP0460200
|
[2-[4-[[(Z)-3-phenylprop-2-enoyl]amino]butyl]-3,4-dihydro-1H-isoquinolin-7-yl] trifluoromethanesulfonate
Show/Hide
|
C23H25F3N2O4S
|
1
|
| 1 |
Ki = 39.81 nM
|
|
|
|
CP0710974
|
4-butyl-N-(isoindolin-5-yl)benzenesulfonamide
Show/Hide
|
C18H22N2O2S
|
1
|
| 1 |
Ki = 39.81 nM
|
|
|
|
CP0710975
|
5-(4-chlorophenyl)-N-(3-methyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-yl)thiophene-2-sulfonamide
Show/Hide
|
C21H21ClN2O2S2
|
1
|
| 1 |
Ki = 39.81 nM
|
|
|
|
CP0379040
|
3-[3-[3-[(4,5-dimethyl-1,2,4-triazol-3-yl)sulfanyl]propyl]-1,2,4,5-tetrahydro-3-benzazepin-7-yl]-5-methyl-1,2-oxazole
Show/Hide
|
C21H27N5OS
|
1
|
| 1 |
Ki = 39.81 nM
|
|
|
|
CP0401590
|
N-ethyl-N-[[5-(5-ethylsulfonyl-2-methoxyphenyl)-1H-pyrrol-2-yl]methyl]ethanamine
Show/Hide
|
C18H26N2O3S
|
1
|
| 1 |
Ki = 39.81 nM
|
|
|
|
CP0086890
|
1-[2-(1,3-dihydroisoindol-2-yl)ethyl]-3-(3-propan-2-yloxyphenyl)imidazolidin-2-one
Show/Hide
|
C22H27N3O2
|
1
|
| 1 |
Ki = 39.81 nM
|
|
|
|
CP0276133
|
1-(3-chloro-2-fluorophenyl)-3-[2-[4-(trifluoromethyl)piperidin-1-yl]ethyl]imidazolidin-2-one
Show/Hide
|
C17H20ClF4N3O
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1
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| 1 |
Ki = 39.81 nM
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CP0181488
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1-[2-[(7,7-dimethyl-1-bicyclo[2.2.1]heptanyl)methyl-methylamino]ethyl]-3-(4-fluorophenyl)imidazolidin-2-one
Show/Hide
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C22H32FN3O
|
1
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| 1 |
Ki = 39.81 nM
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CP0417361
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(4aR,10bR)-4-propyl-2,3,4a,5,6,10b-hexahydrobenzo[h][1,4]benzoxazine-9-carbonitrile
Show/Hide
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C16H20N2O
|
1
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| 1 |
Ki = 39.81 nM
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CP0039125
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4-methyl-5-[4-methyl-5-[3-[6-[4-(trifluoromethyl)phenyl]-3-azabicyclo[4.1.0]heptan-3-yl]propylsulfanyl]-1,2,4-triazol-3-yl]-1,3-oxazole
Show/Hide
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C23H26F3N5OS
|
1
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| 1 |
Ki = 39.81 nM
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CP0356251
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4-[5-[3-[2-[2-fluoro-4-(trifluoromethyl)phenyl]morpholin-4-yl]propylsulfanyl]-4-methyl-1,2,4-triazol-3-yl]benzamide
Show/Hide
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C24H25F4N5O2S
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2
|
| 1 |
Ki = 39.81 nM
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| 2 |
Ki > 10000 nM
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CP0895107
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1-Benzhydryl-4-[4-(3-styryl-isoxazol-5-yl)-butyl]-piperazine hydrochloride
Show/Hide
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C32H36ClN3O
|
1
|
| 1 |
Ki = 40 nM
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CP0878698
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Naphthalene-2-carboxylic acid 4-[4-(2-methoxy-phenyl)-piperazin-1-ylmethyl]-benzylamide oxalic acid
Show/Hide
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C32H33N3O6
|
1
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| 1 |
Ki = 40 nM
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CP0393921
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8-[4-(4-pyrazolo[1,5-a]pyridin-5-yloxybutyl)piperazin-1-yl]-2,3-dihydro-1,4-benzodioxin-5-ol
Show/Hide
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C23H28N4O4
|
1
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| 1 |
Ki = 40 nM
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CP0082972
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11-methyl-11,21-diazatetracyclo[12.7.0.0^{3,8}.0^{15,20}]henicosa-1(14),3(8),4,6,15,17,19-heptaene
Show/Hide
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C20H22N2
|
1
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| 1 |
Ki = 40.3 nM
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CP0445343
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(E)-N-[4-(4-benzhydryl-1,4-diazepan-1-yl)butyl]-3-phenylprop-2-enamide
Show/Hide
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C31H37N3O
|
1
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| 1 |
Ki = 40.9 nM
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CP0321301
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N-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl]-5-phenylpyridin-2-amine
Show/Hide
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C25H28Cl2N4
|
1
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| 1 |
Ki = 41 nM
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CP0380079
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[4-(4-chlorophenyl)-1-[4-(4-fluorophenyl)-4-oxobutyl]piperidin-4-yl] propanoate
Show/Hide
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C24H27ClFNO3
|
1
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| 1 |
Ki = 41 nM
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CP0377888
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Benzyl-[2-(6-chloro-2-trifluoromethyl-1H-benzoimidazol-4-yloxy)-ethyl]-amine
Show/Hide
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C17H15ClF3N3O
|
1
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| 1 |
Ki = 41.8 nM
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CP0898126
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1-(4-Chloro-phenyl)-cyclopentanecarboxylic acid {4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-butyl}-amide oxalic acid
Show/Hide
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C29H38ClN3O6
|
1
|
| 1 |
Ki = 42 nM
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CP0436909
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5-hydroxy-8-(4-methyl-1,4-diazepan-1-yl)-4H-1,4-benzoxazin-3-one
Show/Hide
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C14H19N3O3
|
1
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| 1 |
Ki = 42 nM
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CP0481590
|
N-[3-[2-(benzylamino)ethoxy]phenyl]methanesulfonamide
Show/Hide
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C16H20N2O3S
|
1
|
| 1 |
Ki = 42.5 nM
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CP0515023
|
2-[4-[4-[(4-chlorophenyl)-phenylmethyl]-1,4-diazepan-1-yl]butyl]isoindole-1,3-dione
Show/Hide
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C30H32ClN3O2
|
1
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| 1 |
Ki = 42.9 nM
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CP0498810
|
4-(4-Chloro-phenyl)-1-[4-(4-fluoro-phenyl)-4-oxo-butyl]-piperidine-4-carboxylic acid dimethylamide
Show/Hide
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C24H28ClFN2O2
|
1
|
| 1 |
Ki = 43.2 nM
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CP0849407
|
(R)-5-Dipropylamino-4,5,6,7-tetrahydro-indole-1-carbaldehyde
Show/Hide
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C15H24N2O
|
1
|
| 1 |
Ki = 43.65 nM
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CP0496803
|
N,N-dipropyl-6,7,8,9-tetrahydrobenzo[e][1]benzofuran-8-amine
Show/Hide
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C18H25NO
|
1
|
| 1 |
Ki = 45 nM
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CP0847015
|
1-((S)-7-Dipropylamino-5,6,7,8-tetrahydro-indolizin-3-yl)-ethanone
Show/Hide
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C16H26N2O
|
1
|
| 1 |
Ki = 45.71 nM
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CP0234092
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N-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl]-1-(4-methoxyphenyl)triazole-4-carboxamide
Show/Hide
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C24H28Cl2N6O2
|
1
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| 1 |
Ki = 46 nM
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CP0059819
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11-methyl-11-aza-tricyclo[12.4.0.0.3,8]octadeca-1(18),3(8),4,6,14,16-hexaen-6-ol
Show/Hide
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C18H21NO
|
2
|
| 1 |
Ki = 47 nM
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|
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| 2 |
Ki = 47.5 nM
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CP0385667
|
[4-(4-chlorophenyl)-1-[4-(4-fluorophenyl)-4-oxobutyl]piperidin-4-yl] 3-[2-[[3-[4-(4-chlorophenyl)-1-[4-(4-fluorophenyl)-4-oxobutyl]piperidin-4-yl]oxy-3-oxopropyl]-methylamino]ethyl-methylamino]propanoate
Show/Hide
|
C52H62Cl2F2N4O6
|
1
|
| 1 |
Ki = 47 nM
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CP0426888
|
2-[4-(4-benzhydrylpiperazin-1-yl)butyl]isoindole-1,3-dione
Show/Hide
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C29H31N3O2
|
1
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| 1 |
Ki = 47.3 nM
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CP0408434
|
5-hydroxy-8-(4-methylpiperazin-1-yl)-4H-1,4-benzoxazin-3-one
Show/Hide
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C13H17N3O3
|
1
|
| 1 |
Ki = 48 nM
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CP0883151
|
(S)-7-Dipropylamino-5,6,7,8-tetrahydro-indolizine-3-carbaldehyde oxime
Show/Hide
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C15H25N3O
|
1
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| 1 |
Ki = 48.98 nM
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CP0404449
|
2-{2-[4-(4-Chloro-phenyl)-piperazin-1-yl]-ethyl}-1H-pyrrolo[2,3-b]pyridine
Show/Hide
|
C19H21ClN4
|
1
|
| 1 |
Ki = 50 nM
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|
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CP0400139
|
N-[2-[4-(2,3-dichlorophenyl)piperazin-1-yl]ethyl]-3-ethynylbenzamide
Show/Hide
|
C21H21Cl2N3O
|
1
|
| 1 |
Ki = 50 nM
|
|
|
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CP0371973
|
3-(2-chlorophenothiazin-10-yl)-N-methyl-N-[[4-(3-piperidin-1-ylpropoxy)phenyl]methyl]propan-1-amine
Show/Hide
|
C31H38ClN3OS
|
1
|
| 1 |
Ki = 50 nM
|
|
|
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CP0371976
|
(3E)-3-(2-chlorothioxanthen-9-ylidene)-N-methyl-N-[[4-(3-piperidin-1-ylpropoxy)phenyl]methyl]propan-1-amine
Show/Hide
|
C32H37ClN2OS
|
1
|
| 1 |
Ki = 50 nM
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CP0393922
|
5-[4-(4-pyrazolo[1,5-a]pyridin-5-yloxybutyl)piperazin-1-yl]quinolin-8-ol
Show/Hide
|
C24H27N5O2
|
1
|
| 1 |
Ki = 50 nM
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|
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CP0466321
|
1-[(6R)-6-(dipropylamino)-1-methoxy-5,6,7,8-tetrahydronaphthalen-2-yl]-2-(4-methoxyphenyl)ethanol
Show/Hide
|
C26H37NO3
|
1
|
| 1 |
Ki = 50.12 nM
|
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CP0520876
|
1-[[5-(5-ethylsulfonyl-2-methoxyphenyl)-1H-pyrrol-2-yl]methyl]-2-(3-methoxyphenyl)azepane
Show/Hide
|
C27H34N2O4S
|
1
|
| 1 |
Ki = 50.12 nM
|
|
|
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CP0447750
|
4-Chloro-1-methoxy-naphthalene-2-carboxylic acid [2-(4-phenyl-piperazin-1-yl)-ethyl]-amide
Show/Hide
|
C24H26ClN3O2
|
1
|
| 1 |
Ki = 50.12 nM
|
|
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CP0448550
|
4-Bromo-1-methoxy-naphthalene-2-carboxylic acid {2-[4-(2,3-dimethyl-phenyl)-piperazin-1-yl]-ethyl}-amide
Show/Hide
|
C26H30BrN3O2
|
1
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| 1 |
Ki = 50.12 nM
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CP0511130
|
4-bromo-N-[2-[4-(3-chloro-2-methylphenyl)piperazin-1-yl]ethyl]-1-methoxynaphthalene-2-carboxamide
Show/Hide
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C25H27BrClN3O2
|
1
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| 1 |
Ki = 50.12 nM
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CP0562261
|
4-bromo-N-[2-[4-(2-cyanophenyl)piperazin-1-yl]ethyl]-1-methoxynaphthalene-2-carboxamide
Show/Hide
|
C25H25BrN4O2
|
1
|
| 1 |
Ki = 50.12 nM
|
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|
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CP0377876
|
[(3aS,9bS)-3-[4-[(4-phenylbenzoyl)amino]butyl]-1,2,3a,4,5,9b-hexahydrobenzo[e]indol-7-yl] methanesulfonate
Show/Hide
|
C30H34N2O4S
|
1
|
| 1 |
Ki = 50.12 nM
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CP0460832
|
N-[4-[(3aS,9bR)-1,2,3a,4,5,9b-hexahydrobenzo[e]indol-3-yl]butyl]-4-phenylbenzamide
Show/Hide
|
C29H32N2O
|
1
|
| 1 |
Ki = 50.12 nM
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|
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CP0395351
|
[2-[4-[(3-methyl-4-phenylbenzoyl)amino]butyl]-3,4-dihydro-1H-isoquinolin-7-yl] trifluoromethanesulfonate
Show/Hide
|
C28H29F3N2O4S
|
1
|
| 1 |
Ki = 50.12 nM
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CP0455491
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[2-[4-[[4-(2-methylphenyl)benzoyl]amino]butyl]-3,4-dihydro-1H-isoquinolin-7-yl] trifluoromethanesulfonate
Show/Hide
|
C28H29F3N2O4S
|
1
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| 1 |
Ki = 50.12 nM
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CP0226510
|
1-(3-chlorophenyl)-3-[2-[4-(4-chlorophenyl)piperidin-1-yl]ethyl]imidazolidin-2-one
Show/Hide
|
C22H25Cl2N3O
|
1
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| 1 |
Ki = 50.12 nM
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CP0654478
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1-(benzo[d][1,3]dioxol-5-yl)-3-(2-(((-7,7-dimethylbicyclo[2.2.1]heptan-1-yl)methyl)(methyl)amino)ethyl)imidazolidin-2-one
Show/Hide
|
C23H33N3O3
|
1
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| 1 |
Ki = 50.12 nM
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CP0254455
|
4-methyl-5-[4-methyl-5-[3-[(1R,5S)-1-[4-(trifluoromethyl)phenyl]-3-azabicyclo[3.1.0]hexan-3-yl]propylsulfanyl]-1,2,4-triazol-3-yl]-1,3-oxazole
Show/Hide
|
C22H24F3N5OS
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1
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| 1 |
Ki = 50.12 nM
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CP0042189
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N-[3-[[4-methyl-5-(4-methyl-1,3-oxazol-5-yl)-1,2,4-triazol-3-yl]sulfanyl]propyl]-1-phenylbicyclo[3.1.0]hexan-3-amine
Show/Hide
|
C22H27N5OS
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1
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| 1 |
Ki = 50.12 nM
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CP0100831
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5-[5-[3-(5-fluorospiro[1,2-dihydroindene-3,3'-pyrrolidine]-1'-yl)propylsulfanyl]-4-methyl-1,2,4-triazol-3-yl]-2,4-dimethyl-1,3-thiazole
Show/Hide
|
C23H28FN5S2
|
1
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| 1 |
Ki = 50.12 nM
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CP0308462
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4-methyl-5-[4-methyl-5-[3-[(1S,5R)-3-[3-(trifluoromethyl)phenyl]-8-azabicyclo[3.2.1]octan-8-yl]propylsulfanyl]-1,2,4-triazol-3-yl]-1,3-oxazole
Show/Hide
|
C24H28F3N5OS
|
1
|
| 1 |
Ki = 50.12 nM
|
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CP0439809
|
(E)-N-[4-(2,5-diazatetracyclo[13.4.0.02,7.08,13]nonadeca-1(19),8,10,12,15,17-hexaen-5-yl)butyl]-3-phenylprop-2-enamide
Show/Hide
|
C30H33N3O
|
1
|
| 1 |
Ki = 50.2 nM
|
|
|
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CP0171880
|
N-[5-[4-(2-methoxyphenyl)piperazin-1-yl]pentyl]pyrazolo[1,5-a]pyridine-2-carboxamide
Show/Hide
|
C24H31N5O2
|
1
|
| 1 |
Ki = 51.29 nM
|
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|
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CP0894976
|
1-Benzhydryl-4-[4-(3-thiophen-2-yl-isoxazol-5-yl)-butyl]-piperazine hydrochloride
Show/Hide
|
C28H32ClN3OS
|
1
|
| 1 |
Ki = 52 nM
|
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|
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CP0175178
|
11-methyl-11-aza-tricyclo[12.4.0.03,8]octadeca-1(18),3(8),4,6,14,16-hexaene
Show/Hide
|
C18H21N
|
1
|
| 1 |
Ki = 52.5 nM
|
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CP0332247
|
N-[4-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]butyl]quinolin-2-amine
Show/Hide
|
C24H27F3N4
|
1
|
| 1 |
Ki = 53 nM
|
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CP0373605
|
1-(4-Fluorophenyl)-4-[4-([2.2]paracyclophan-4-yl)-4-hydroxypiperidin-1-yl]butan-1-one
Show/Hide
|
C31H34FNO2
|
1
|
| 1 |
Ki = 53 nM
|
|
|
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CP0476090
|
4-methyl-5-[4-methyl-5-[2-[(2R,3S)-2-[4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptan-5-yl]ethylsulfanyl]-1,2,4-triazol-3-yl]-1,3-oxazole
Show/Hide
|
C22H24F3N5OS
|
1
|
| 1 |
Ki = 53.7 nM
|
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|
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CP0436719
|
N,N-dipropyl-6,7,8,9-tetrahydrobenzo[g][1]benzofuran-7-amine
Show/Hide
|
C18H25NO
|
1
|
| 1 |
Ki = 56 nM
|
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|
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CP0445440
|
4-(4-Benzyl-piperazin-1-yl)-7-bromo-1H-indole
Show/Hide
|
C19H20BrN3
|
1
|
| 1 |
Ki = 56 nM
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CP0510969
|
[4-(4-chlorophenyl)-1-[4-(4-fluorophenyl)-4-oxobutyl]piperidin-4-yl] acetate
Show/Hide
|
C23H25ClFNO3
|
1
|
| 1 |
Ki = 56 nM
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CP0122849
|
4-(4-Benzyl-piperazin-1-yl)-1,3-dihydro-benzoimidazol-2-one
Show/Hide
|
C18H20N4O
|
1
|
| 1 |
Ki = 56.5 nM
|
|
|
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CP0332248
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N-[4-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]butyl]isoquinolin-1-amine
Show/Hide
|
C24H27F3N4
|
1
|
| 1 |
Ki = 58 nM
|
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CP0247588
|
N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]-2,1,3-benzoxadiazole-5-carboxamide
Show/Hide
|
C22H27N5O3
|
1
|
| 1 |
Ki = 58.5 nM
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CP0491857
|
5,6,6a,7-Tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol; hydrochloride
Show/Hide
|
C16H15NO2
|
1
|
| 1 |
Ki = 58.88 nM
|
|
|
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CP0072419
|
(SNAP-8719)[4-(4-Amino-6,7-dimethoxy-quinazolin-2-yl)-octahydro-quinoxalin-1-yl]-furan-2-yl-methanone
Show/Hide
|
C22H28F3N3O2
|
1
|
| 1 |
Ki = 59 nM
|
|
|
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CP0897820
|
1-{4-[3-(3-Nitro-phenyl)-isoxazol-5-yl]-butyl}-4-phenyl-piperazine hydrochloride
Show/Hide
|
C23H27ClN4O3
|
1
|
| 1 |
Ki = 60 nM
|
|
|
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CP0910275
|
2-((S)-7-Dipropylamino-5,6,7,8-tetrahydro-indolizin-3-ylmethylene)-malononitrile
Show/Hide
|
C18H24N4
|
1
|
| 1 |
Ki = 60.26 nM
|
|
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CP0486216
|
1-[[3-methoxy-4-[3-[1-[2-[2-[2-[4-[3-[2-methoxy-4-[[4-(2-methoxyphenyl)piperazin-1-yl]methyl]phenoxy]propyl]triazol-1-yl]ethoxy]ethoxy]ethyl]triazol-4-yl]propoxy]phenyl]methyl]-4-(2-methoxyphenyl)piperazine
Show/Hide
|
C54H72N10O8
|
1
|
| 1 |
Ki = 61 nM
|
|
|
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CP0550959
|
1-(N-benzyl-2,4-dichloroanilino)-3-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]urea
Show/Hide
|
C28H33Cl2N5O2
|
1
|
| 1 |
Ki = 61 nM
|
|
|
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CP0384600
|
4-[(1R)-1-hydroxy-2-[2-[3-methoxy-4-(3-phenylpropoxy)phenyl]ethylamino]ethyl]benzene-1,2-diol
Show/Hide
|
C26H31NO5
|
1
|
| 1 |
Ki = 62 nM
|
|
|
|
CP0058606
|
3-[3-(4-benzhydrylpiperazin-1-yl)propyl]-1H-benzimidazol-2-one
Show/Hide
|
C27H30N4O
|
1
|
| 1 |
Ki = 62.7 nM
|
|
|
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CP0438583
|
1-[(6R)-6-(dipropylamino)-1-methoxy-5,6,7,8-tetrahydronaphthalen-2-yl]-2-phenylethanol
Show/Hide
|
C25H35NO2
|
1
|
| 1 |
Ki = 63.1 nM
|
|
|
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CP0392514
|
(4aR,11bR)-4-(cyclopropylmethyl)-2,3,4a,5,6,8,9,11b-octahydro-[1]benzofuro[5,6-h][1,4]benzoxazine
Show/Hide
|
C18H23NO2
|
1
|
| 1 |
Ki = 63.1 nM
|
|
|
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CP0406992
|
4-Bromo-1-methoxy-naphthalene-2-carboxylic acid [2-(4-o-tolyl-piperazin-1-yl)-ethyl]-amide
Show/Hide
|
C25H28BrN3O2
|
1
|
| 1 |
Ki = 63.1 nM
|
|
|
|
CP0438570
|
CHEMBL351722
Show/Hide
|
C27H28N4O
|
1
|
| 1 |
Ki = 63.1 nM
|
|
|
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CP0498666
|
2-(5-ethylsulfonyl-2-methoxyphenyl)-5-(pyrrolidin-1-ylmethyl)-1H-pyrrole
Show/Hide
|
C18H24N2O3S
|
1
|
| 1 |
Ki = 63.1 nM
|
|
|
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CP0201570
|
1-(1-benzothiophen-5-yl)-3-[2-(1,3-dihydroisoindol-2-yl)ethyl]imidazolidin-2-one
Show/Hide
|
C21H21N3OS
|
1
|
| 1 |
Ki = 63.1 nM
|
|
|
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CP0295405
|
1-[2-(1,3-dihydroisoindol-2-yl)ethyl]-3-(6-methylpyridin-3-yl)imidazolidin-2-one
Show/Hide
|
C19H22N4O
|
1
|
| 1 |
Ki = 63.1 nM
|
|
|
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CP0049015
|
2-methyl-7-[3-[[4-methyl-5-(2-methylquinolin-5-yl)-1,2,4-triazol-3-yl]sulfanyl]propyl]-5,6,8,9-tetrahydro-[1,3]oxazolo[4,5-h][3]benzazepine
Show/Hide
|
C28H30N6OS
|
1
|
| 1 |
Ki = 63.1 nM
|
|
|
|
CP0103105
|
2-methyl-8-[3-[[4-methyl-5-(2-methylquinolin-5-yl)-1,2,4-triazol-3-yl]sulfanyl]propyl]-6,7,9,10-tetrahydro-[1,3]oxazolo[5,4-i][3]benzazepine
Show/Hide
|
C28H30N6OS
|
1
|
| 1 |
Ki = 63.1 nM
|
|
|
|
CP0190893
|
N-[5-[4-(2-methoxyphenyl)piperazin-1-yl]pentyl]pyrazolo[1,5-a]pyridine-3-carboxamide
Show/Hide
|
C24H31N5O2
|
1
|
| 1 |
Ki = 64.57 nM
|
|
|
|
CP0465795
|
((S)-1-Benzyl-pyrrolidin-3-ylmethyl)-[2-(5-bromo-2-methoxy-phenyl)-oxazol-4-ylmethyl]-amine
Show/Hide
|
C23H26BrN3O2
|
1
|
| 1 |
Ki = 65 nM
|
|
|
|
CP0424210
|
2-(4-(4-(2-methoxyphenyl)-1-piperazinyl)butyl)-1,2-benzisothiazole-3(2H)-one 1,1-dioxide
Show/Hide
|
C21H25N3O3S
|
1
|
| 1 |
Ki = 66 nM
|
|
|
|
CP0178943
|
1-(2-fluorophenyl)-4-((1-phenyl-1H-pyrazol-4-yl)methyl)piperazine
Show/Hide
|
C20H21FN4
|
2
|
| 1 |
Ki = 67 nM
|
|
|
| 2 |
Ki = 67.61 nM
|
|
|
|
CP0423208
|
N-methyl-N-[[4-(3-piperidin-1-ylpropoxy)phenyl]methyl]-3-(2-tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,11,13-hexaenylidene)propan-1-amine
Show/Hide
|
C34H42N2O
|
1
|
| 1 |
Ki = 67 nM
|
|
|
|
CP0198140
|
2-(1H-benzimidazol-4-yloxy)-N-benzylethanamine
Show/Hide
|
C16H17N3O
|
1
|
| 1 |
Ki = 67.2 nM
|
|
|
|
CP0330402
|
1-benzyl-N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]-5-methyltriazole-4-carboxamide
Show/Hide
|
C26H34N6O2
|
1
|
| 1 |
Ki = 67.61 nM
|
|
|
|
CP0102434
|
B-HT 920
Show/Hide
|
C10H15N3S
|
1
|
| 1 |
Ki = 67.61 nM
|
|
|
|
CP0393065
|
N-[2-[4-(2,3-dichlorophenyl)piperazin-1-yl]ethyl]-3-(2-phenylethynyl)benzamide
Show/Hide
|
C27H25Cl2N3O
|
1
|
| 1 |
Ki = 68 nM
|
|
|
|
CP0338014
|
AJ 76
Show/Hide
|
C15H23NO
|
1
|
| 1 |
Ki = 70 nM
|
|
|
|
CP0228156
|
N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]isoquinolin-1-amine
Show/Hide
|
C24H30N4O
|
1
|
| 1 |
Ki = 70 nM
|
|
|
|
CP0405821
|
N-(3-formylpyrazolo[1,5-a]pyridin-5-yl)-4-[4-(2-methoxyphenyl)piperazin-1-yl]butanamide
Show/Hide
|
C23H27N5O3
|
1
|
| 1 |
Ki = 70 nM
|
|
|
|
CP0360721
|
1-(2-methoxyphenyl)-4-((1-(pyridin-2-yl)-1H-pyrazol-4-yl)methyl)piperazine
Show/Hide
|
C20H23N5O
|
2
|
| 1 |
Ki = 72 nM
|
|
|
| 2 |
Ki = 72.44 nM
|
|
|
|
CP0460185
|
1-[[3-methoxy-4-[3-[1-[2-[2-[2-[2-[4-[3-[2-methoxy-4-[[4-(2-methoxyphenyl)piperazin-1-yl]methyl]phenoxy]propyl]triazol-1-yl]ethoxy]ethoxy]ethoxy]ethyl]triazol-4-yl]propoxy]phenyl]methyl]-4-(2-methoxyphenyl)piperazine
Show/Hide
|
C56H76N10O9
|
1
|
| 1 |
Ki = 72 nM
|
|
|
|
CP0377118
|
4-[4-(4-Chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(2,5-dimethylphenyl)butan-1-one
Show/Hide
|
C23H28ClNO2
|
1
|
| 1 |
Ki = 73 nM
|
|
|
|
CP0479115
|
1-[[3-methoxy-4-[4-[1-[10-[4-[4-[2-methoxy-4-[[4-(2-methoxyphenyl)piperazin-1-yl]methyl]phenoxy]butyl]triazol-1-yl]decyl]triazol-4-yl]butoxy]phenyl]methyl]-4-(2-methoxyphenyl)piperazine
Show/Hide
|
C60H84N10O6
|
1
|
| 1 |
Ki = 74 nM
|
|
|
|
CP0382976
|
2-(1-benzylpyrrolidin-3-yl)-N-[[2-(5-bromo-2-methoxyphenyl)-1,3-oxazol-4-yl]methyl]ethanamine
Show/Hide
|
C24H28BrN3O2
|
1
|
| 1 |
Ki = 75 nM
|
|
|
|
CP0040242
|
16-methoxy-11-methyl-11-aza-tricyclo[12.4.0.03,8]octadeca-1(18),3(8),4,6,14,16-hexaene
Show/Hide
|
C19H23NO
|
1
|
| 1 |
Ki = 75.7 nM
|
|
|
|
CP0382812
|
4-[4-(2,5-Dimethylphenyl)piperazin-1-yl]-1-(4-fluorophenyl)-butan-1-one
Show/Hide
|
C22H27FN2O
|
1
|
| 1 |
Ki = 76 nM
|
|
|
|
CP0490071
|
1-[N-[(2-fluorophenyl)methyl]-4-methoxyanilino]-3-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]urea
Show/Hide
|
C29H36FN5O3
|
1
|
| 1 |
Ki = 76 nM
|
|
|
|
CP0528981
|
1-(N-benzyl-4-fluoroanilino)-3-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]urea
Show/Hide
|
C29H36FN5O2
|
1
|
| 1 |
Ki = 76 nM
|
|
|
|
CP0434990
|
5-[4-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]triazol-1-yl]pyrazolo[1,5-a]pyridine
Show/Hide
|
C23H27N7O
|
1
|
| 1 |
Ki = 77 nM
|
|
|
|
CP0494704
|
N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]quinoxaline-6-carboxamide
Show/Hide
|
C24H29N5O2
|
1
|
| 1 |
Ki = 77.9 nM
|
|
|
|
CP0393637
|
5-(2-ethoxyethoxy)-N-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]pyrazolo[1,5-a]pyridine-3-carboxamide
Show/Hide
|
C26H35N5O4
|
1
|
| 1 |
Ki = 78 nM
|
|
|
|
CP0410107
|
7-[4-(3,4-Dimethyl-phenyl)-piperazin-1-ylmethyl]-4H-benzo[1,4]oxazin-3-one
Show/Hide
|
C21H25N3O2
|
1
|
| 1 |
Ki = 78.5 nM
|
|
|
|
CP0532952
|
CHEMBL4745809
Show/Hide
|
C24H35ClN2O2
|
1
|
| 1 |
Ki = 79.1 nM
|
|
|
|
CP0404375
|
4-methoxy-N-phenyl-3-[5-[(2-phenylazepan-1-yl)methyl]-1H-pyrrol-2-yl]benzenesulfonamide
Show/Hide
|
C30H33N3O3S
|
1
|
| 1 |
Ki = 79.43 nM
|
|
|
|
CP0492450
|
(4aR,11bR)-4-methyl-2,3,4a,5,6,8,9,11b-octahydro-[1]benzofuro[5,6-h][1,4]benzoxazine
Show/Hide
|
C15H19NO2
|
1
|
| 1 |
Ki = 79.43 nM
|
|
|
|
CP0487301
|
4-bromo-1-ethoxy-N-[2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl]naphthalene-2-carboxamide
Show/Hide
|
C26H30BrN3O3
|
1
|
| 1 |
Ki = 79.43 nM
|
|
|
|
CP0497765
|
4-bromo-1-methoxy-N-[2-(4-pyridin-2-ylpiperazin-1-yl)ethyl]naphthalene-2-carboxamide
Show/Hide
|
C23H25BrN4O2
|
1
|
| 1 |
Ki = 79.43 nM
|
|
|
|
CP0498308
|
4-Bromo-1-methoxy-naphthalene-2-carboxylic acid {2-[4-(2-methoxy-phenyl)-piperazin-1-yl]-ethyl}-amide
Show/Hide
|
C25H28BrN3O3
|
1
|
| 1 |
Ki = 79.43 nM
|
|
|
|
CP0502923
|
4-bromo-1-ethoxy-N-[2-(4-pyridin-2-ylpiperazin-1-yl)ethyl]naphthalene-2-carboxamide
Show/Hide
|
C24H27BrN4O2
|
1
|
| 1 |
Ki = 79.43 nM
|
|
|
|
CP0551179
|
4-bromo-1-methoxy-N-[2-(4-phenylpiperidin-1-yl)ethyl]naphthalene-2-carboxamide
Show/Hide
|
C25H27BrN2O2
|
1
|
| 1 |
Ki = 79.43 nM
|
|
|
|
CP0403959
|
2-benzyl-7-methoxy-3,3a,4,9b-tetrahydro-1H-chromeno[3,4-c]pyrrole
Show/Hide
|
C19H21NO2
|
1
|
| 1 |
Ki = 79.43 nM
|
|
|
|
CP0496477
|
2-benzyl-8-methoxy-3,3a,4,9b-tetrahydro-1H-chromeno[3,4-c]pyrrole
Show/Hide
|
C19H21NO2
|
1
|
| 1 |
Ki = 79.43 nM
|
|
|
|
CP0315215
|
1-[(3,4-dichlorophenyl)methyl]-3-[2-(1,3-dihydroisoindol-2-yl)ethyl]imidazolidin-2-one
Show/Hide
|
C20H21Cl2N3O
|
1
|
| 1 |
Ki = 79.43 nM
|
|
|
|
CP0092521
|
1-(3-chlorophenyl)-3-[(2S)-2-(methoxymethyl)pyrrolidin-1-yl]imidazolidin-2-one
Show/Hide
|
C15H20ClN3O2
|
1
|
| 1 |
Ki = 79.43 nM
|
|
|
|
CP0340828
|
5-[5-[3-(8-methoxyspiro[2,3-dihydro-1H-naphthalene-4,3'-pyrrolidine]-1'-yl)propylsulfanyl]-4-methyl-1,2,4-triazol-3-yl]-4-methyl-1,3-oxazole
Show/Hide
|
C24H31N5O2S
|
1
|
| 1 |
Ki = 79.43 nM
|
|
|
|
CP0424212
|
1-(4-(4-(2-methoxyphenyl)-1-piperazinyl)butyl)-indolin-2-one
Show/Hide
|
C22H27N3O
|
1
|
| 1 |
Ki = 80 nM
|
|
|
|
CP0393889
|
1-(4-Chloro-benzyl)-4-[3-(4-chloro-phenyl)-isoxazol-5-yl]-piperidine
Show/Hide
|
C21H20Cl2N2O
|
1
|
| 1 |
Ki = 81 nM
|
|
|
|
CP0403563
|
(S)-8-(Benzylamino-methyl)-3,6,7,8-tetrahydro-1H-chromeno[7,8-d]imidazol-2-one
Show/Hide
|
C18H19N3O2
|
1
|
| 1 |
Ki = 81 nM
|
|
|
|
CP0463611
|
bis[4-(4-chlorophenyl)-1-[4-(4-fluorophenyl)-4-oxobutyl]piperidin-4-yl] icosanedioate
Show/Hide
|
C62H80Cl2F2N2O6
|
1
|
| 1 |
Ki = 82 nM
|
|
|
|
CP0463689
|
1-(1-benzylpyrrolidin-3-yl)-N-[[2-(5-bromo-2-methoxyphenyl)-1,3-oxazol-4-yl]methyl]methanamine
Show/Hide
|
C23H26BrN3O2
|
1
|
| 1 |
Ki = 83 nM
|
|
|
|
CP0086686
|
N-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl]-4-[1-(4-methoxyphenyl)triazol-4-yl]butanamide
Show/Hide
|
C27H34Cl2N6O2
|
1
|
| 1 |
Ki = 83 nM
|
|
|
|
CP0372555
|
N-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]-4-[2-[2-[2-[2-[[4-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propylcarbamoyl]phenyl]methoxy]ethoxy]ethoxy]ethoxy]ethoxymethyl]benzamide
Show/Hide
|
C52H72N6O9
|
1
|
| 1 |
Ki = 83 nM
|
|
|
|
CP0413871
|
1-(azulen-1-ylmethyl)-4-(2-methoxyphenyl)piperazine
Show/Hide
|
C22H24N2O
|
1
|
| 1 |
Ki = 83 nM
|
|
|
|
CP0535738
|
1-(4-Fluoro-phenyl)-4-(1,2,4,4a,5,6-hexahydro-pyrazino[1,2-a]quinolin-3-yl)-butan-1-one
Show/Hide
|
C22H25FN2O
|
1
|
| 1 |
Ki = 83.5 nM
|
|
|
|
CP0440814
|
1-[[3-methoxy-4-[3-[1-[8-[4-[3-[2-methoxy-4-[[4-(2-methoxyphenyl)piperazin-1-yl]methyl]phenoxy]propyl]triazol-1-yl]octyl]triazol-4-yl]propoxy]phenyl]methyl]-4-(2-methoxyphenyl)piperazine
Show/Hide
|
C56H76N10O6
|
1
|
| 1 |
Ki = 84 nM
|
|
|
|
CP0378037
|
N-[4-[4-(5-methoxy-1,2-benzoxazol-3-yl)piperazin-1-yl]butyl]-2,1,3-benzoxadiazole-5-carboxamide
Show/Hide
|
C23H26N6O4
|
1
|
| 1 |
Ki = 85 nM
|
|
|
|
CP0426039
|
N-[4-[2-[4-(2,3-dichlorophenyl)piperazin-1-yl]ethyl]cyclohexyl]-N-propylcyclohexanecarboxamide
Show/Hide
|
C28H43Cl2N3O
|
1
|
| 1 |
Ki = 85 nM
|
|
|
|
CP0379917
|
1-(4-chlorophenyl)-4-[[3-[[4-(2-methoxyphenyl)piperazin-1-yl]methyl]azulen-1-yl]methyl]piperazine
Show/Hide
|
C33H37ClN4O
|
1
|
| 1 |
Ki = 85 nM
|
|
|
|
CP0450724
|
1-[4-fluoro-N-[(4-fluorophenyl)methyl]anilino]-3-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]urea
Show/Hide
|
C28H33F2N5O2
|
1
|
| 1 |
Ki = 85 nM
|
|
|
|
CP0378942
|
6-Fluoro-pyridine-2-carboxylic acid {4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-butyl}-amide
Show/Hide
|
C21H27FN4O2
|
1
|
| 1 |
Ki = 86 nM
|
|
|
|
CP0429280
|
1-[N-[(3-fluorophenyl)methyl]-4-methoxyanilino]-3-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]urea
Show/Hide
|
C29H36FN5O3
|
1
|
| 1 |
Ki = 86 nM
|
|
|
|
CP0442183
|
(3-{4-[1-((E)-4-{2-[4-(3-Diethylamino-propoxy)-phenyl]-benzoimidazol-1-yl}-but-2-enyl)-1H-benzoimidazol-2-yl]-phenoxy}-propyl)-diethyl-amine
Show/Hide
|
C44H54N6O2
|
1
|
| 1 |
Ki = 87 nM
|
|
|
|
CP0380841
|
1-[2-[2,3-dihydro-1H-inden-2-yl(propyl)amino]ethyl]-3-(3,4,5-trifluorophenyl)iminourea
Show/Hide
|
C21H23F3N4O
|
1
|
| 1 |
Ki = 87 nM
|
|
|
|
CP0487886
|
1-(2-methoxyphenyl)-4-(5-naphthalen-2-yloxypentyl)piperazine
Show/Hide
|
C26H32N2O2
|
1
|
| 1 |
Ki = 87 nM
|
|
|
|
CP0160140
|
1-[(4-methoxyphenyl)methyl]-N-[5-[4-(2-methoxyphenyl)piperazin-1-yl]pentyl]-5-methyltriazole-4-carboxamide
Show/Hide
|
C28H38N6O3
|
1
|
| 1 |
Ki = 87.1 nM
|
|
|
|
CP0853782
|
2,2,2-Trichloro-1-((R)-7-dipropylamino-5,6,7,8-tetrahydro-indolizin-3-yl)-ethanone
Show/Hide
|
C16H23Cl3N2O
|
1
|
| 1 |
Ki = 87.1 nM
|
|
|
|
CP0045385
|
CAS_15676-16-1
Show/Hide
|
C15H23N3O4S
|
1
|
| 1 |
Ki = 88 nM
|
|
|
|
CP0025667
|
2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl-2,3-dihydro-indol-1-yl)-ethanone
Show/Hide
|
C18H19ClN4
|
6
|
| 1 |
Ki = 88 nM
|
|
|
| 2 |
Ki = 100 nM
|
|
|
| 3 |
Ki = 200 nM
|
|
|
| 4 |
Ki = 295 nM
|
|
|
| 5 |
Ki = 454 nM
|
|
|
| 6 |
Ki = 960 nM
|
|
|
|
CP0536406
|
1-[4-fluoro-N-[(3-fluorophenyl)methyl]anilino]-3-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]urea
Show/Hide
|
C28H33F2N5O2
|
1
|
| 1 |
Ki = 88 nM
|
|
|
|
CP0410997
|
4-bromo-N-[2-[4-[2-(1H-indol-3-yl)ethyl]piperazin-1-yl]ethyl]-N-propylaniline
Show/Hide
|
C25H33BrN4
|
1
|
| 1 |
Ki = 89 nM
|
|
|
|
CP0477093
|
1-[4-bromo-N-[(2-fluorophenyl)methyl]anilino]-3-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]urea
Show/Hide
|
C28H33BrFN5O2
|
1
|
| 1 |
Ki = 92 nM
|
|
|
|
CP0785349
|
4-phenyl-1-((1-phenyl-1H-1,2,3-triazol-4-yl)methyl)piperidine
Show/Hide
|
C20H22N4
|
1
|
| 1 |
Ki = 93.33 nM
|
|
|
|
CP0378750
|
4-phenyl-1-((1-phenyl-1H-1,2,3-triazol-4-yl)methyl)-1,2,3,6-tetrahydropyridine
Show/Hide
|
C20H20N4
|
1
|
| 1 |
Ki = 94 nM
|
|
|
|
CP0169492
|
Benzyl-[2-(2-methyl-1H-benzoimidazol-4-yloxy)-ethyl]-amine
Show/Hide
|
C17H19N3O
|
1
|
| 1 |
Ki = 94.6 nM
|
|
|
|
CP0348803
|
3-(4-Phenyl-piperidin-1-ylmethyl)-1H-indole
Show/Hide
|
C20H22N2
|
1
|
| 1 |
Ki = 95 nM
|
|
|
|
CP0536911
|
1-[4-chloro-N-[(2-fluorophenyl)methyl]anilino]-3-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]urea
Show/Hide
|
C28H33ClFN5O2
|
1
|
| 1 |
Ki = 95 nM
|
|
|
|
CP0423060
|
4-(4-Benzyl-piperazin-1-yl)-5-chloro-1H-indole
Show/Hide
|
C19H20ClN3
|
1
|
| 1 |
Ki = 95.3 nM
|
|
|
|
CP0372224
|
1-[(4aR,10bR)-4-propyl-2,3,4a,5,6,10b-hexahydrobenzo[h][1,4]benzoxazin-9-yl]ethanone
Show/Hide
|
C17H23NO2
|
1
|
| 1 |
Ki = 95.5 nM
|
|
|
|
CP0479116
|
1-[[3-methoxy-4-[3-[1-[10-[4-[3-[2-methoxy-4-[[4-(2-methoxyphenyl)piperazin-1-yl]methyl]phenoxy]propyl]triazol-1-yl]decyl]triazol-4-yl]propoxy]phenyl]methyl]-4-(2-methoxyphenyl)piperazine
Show/Hide
|
C58H80N10O6
|
1
|
| 1 |
Ki = 96 nM
|
|
|
|
CP0405822
|
4-[4-(2-methoxyphenyl)piperazin-1-yl]-N-pyrazolo[1,5-a]pyridin-5-ylbutanamide
Show/Hide
|
C22H27N5O2
|
1
|
| 1 |
Ki = 97 nM
|
|
|
|
CP0407871
|
7-methoxy-N-(4-(4-(5-methoxybenzo[d]isoxazol-3-yl)piperazin-1-yl)butyl)benzofuran-2-carboxamide
Show/Hide
|
C26H30N4O5
|
1
|
| 1 |
Ki = 98 nM
|
|
|
|
CP0460995
|
2-[4-[4-(8-oxo-6-thiatricyclo[8.4.0.03,7]tetradeca-1(14),3(7),4,10,12-pentaen-2-ylidene)piperidin-1-yl]butyl]isoindole-1,3-dione
Show/Hide
|
C30H28N2O3S
|
1
|
| 1 |
Ki = 99.1 nM
|
|
|
|
CP0424337
|
1-[[5-(5-ethylsulfonyl-2-methoxyphenyl)-1H-pyrrol-2-yl]methyl]-2-(2-methylphenyl)azepane
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C27H34N2O3S
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1
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| 1 |
Ki = 100 nM
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CP0439018
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2-[(2R,5S)-1-ethyl-5-phenylpyrrolidin-2-yl]-5-(5-ethylsulfonyl-2-methoxyphenyl)-1H-pyrrole
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C25H30N2O3S
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1
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| 1 |
Ki = 100 nM
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CP0534141
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4-bromo-N-[2-[4-(2,4-dichlorophenyl)piperazin-1-yl]ethyl]-1-methoxynaphthalene-2-carboxamide
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C24H24BrCl2N3O2
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1
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| 1 |
Ki = 100 nM
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CP0895149
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Naphthalene-2-carboxylic acid 3-[4-(2-methoxy-phenyl)-piperazin-1-ylmethyl]-benzylamide oxalic acid
Show/Hide
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C32H33N3O6
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1
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| 1 |
Ki = 100 nM
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CP0207464
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7-methyl-6,7,8,9,10,15-hexahydro-5H-dibenzo[d,g]azacycloundecene-3-ol
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C19H23NO
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1
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| 1 |
Ki = 100 nM
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CP0086891
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1-(4-tert-butylphenyl)-3-[2-(1,3-dihydroisoindol-2-yl)ethyl]imidazolidin-2-one
Show/Hide
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C23H29N3O
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1
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| 1 |
Ki = 100 nM
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CP0092518
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1-(3-chlorophenyl)-3-[2-(3-phenylmethoxypiperidin-1-yl)ethyl]imidazolidin-2-one
Show/Hide
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C23H28ClN3O2
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1
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| 1 |
Ki = 100 nM
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CP0306761
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2-((4-(2-Fluorophenyl)piperidin-1-yl)methyl)-1-methyl-1H-benzo-[d]imidazole
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C20H22FN3
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1
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| 1 |
Ki = 100 nM
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CP0354658
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4-methyl-5-[4-methyl-5-[3-[1-[2-methyl-4-(trifluoromethyl)phenyl]-3-azabicyclo[3.1.0]hexan-3-yl]propylsulfanyl]-1,2,4-triazol-3-yl]-1,3-oxazole
Show/Hide
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C23H26F3N5OS
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1
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| 1 |
Ki = 100 nM
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CP0105803
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1'-[3-[[4-methyl-5-(4-methyl-1,3-oxazol-5-yl)-1,2,4-triazol-3-yl]sulfanyl]propyl]spiro[2,3-dihydrochromene-4,3'-pyrrolidine]
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C22H27N5O2S
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1
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| 1 |
Ki = 100 nM
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CP0333691
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5-[5-[3-(7-methoxyspiro[2,3-dihydro-1H-naphthalene-4,3'-pyrrolidine]-1'-yl)propylsulfanyl]-4-methyl-1,2,4-triazol-3-yl]-4-methyl-1,3-oxazole
Show/Hide
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C24H31N5O2S
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1
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| 1 |
Ki = 100 nM
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CP0375474
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1-cyclohexyl-4-[[3-methoxy-4-[3-[1-[8-[4-[3-[2-methoxy-4-[[4-(2-methoxyphenyl)piperazin-1-yl]methyl]phenoxy]propyl]triazol-1-yl]octyl]triazol-4-yl]propoxy]phenyl]methyl]piperazine
Show/Hide
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C55H80N10O5
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1
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| 1 |
Ki = 100 nM
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CP0393636
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N-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]-4-[2-[2-[2-[2-[2-[[4-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propylcarbamoyl]phenyl]methoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxymethyl]benzamide
Show/Hide
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C54H76N6O10
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1
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| 1 |
Ki = 100 nM
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CP0498535
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CHEMBL4780335
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C24H31ClN2O2
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1
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| 1 |
Ki = 101.4 nM
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CP0407869
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7-methoxy-N-(4-(4-(7-methoxyisoquinolin-1-yl)piperazin-1-yl)butyl)benzofuran-2-carboxamide
Show/Hide
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C28H32N4O4
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1
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| 1 |
Ki = 102 nM
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CP0463017
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3-(4-(4-(3-a,a,a-trifluorotolyl)-1-piperazinyl)butyl)-quinazolin-4(3H)-one
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C23H25F3N4O
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1
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| 1 |
Ki = 102 nM
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CP0371905
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2-(4-(4-(3-a,a,a-trifluorotolyl)-1-piperazinyl)butyl)-1, 2-benzisothiazole-3(2H)-one 1,1-dioxide
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C22H24F3N3O3S
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1
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| 1 |
Ki = 107 nM
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CP0880911
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N-{3-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-propyl}-2-naphthalen-1-yl-acetamide oxalic acid
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C28H33N3O6
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1
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| 1 |
Ki = 108 nM
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CP0393675
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N-[4-[4-[4-[2-[2-[2-[2-[[4-[4-(4-benzamidobutyl)piperazin-1-yl]-3-methoxyphenyl]methoxy]ethoxy]ethoxy]ethoxy]ethoxymethyl]-2-methoxyphenyl]piperazin-1-yl]butyl]benzamide
Show/Hide
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C54H76N6O9
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1
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| 1 |
Ki = 110 nM
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CP0477390
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8-piperazin-1-yl-2,3-dihydro-1,4-benzodioxin-5-ol
Show/Hide
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C12H16N2O3
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1
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| 1 |
Ki = 110 nM
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CP0468619
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1-[4-fluoro-N-[(4-phenylphenyl)methyl]anilino]-3-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]urea
Show/Hide
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C34H38FN5O2
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1
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| 1 |
Ki = 110 nM
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CP0463625
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((S)-1-Benzyl-pyrrolidin-3-ylmethyl)-[2-(5-bromo-2-methoxy-phenyl)-thiazol-4-ylmethyl]-amine
Show/Hide
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C23H26BrN3OS
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1
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| 1 |
Ki = 115 nM
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CP0492079
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N-[4-[4-(5-methoxy-1,2-benzoxazol-3-yl)piperazin-1-yl]butyl]-1,3-benzodioxole-5-carboxamide
Show/Hide
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C24H28N4O5
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1
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| 1 |
Ki = 118 nM
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CP0391933
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2-[(3R)-1-benzylpyrrolidin-3-yl]-N-[[2-(5-bromo-2-methoxyphenyl)-1,3-oxazol-4-yl]methyl]ethanamine
Show/Hide
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C24H28BrN3O2
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1
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| 1 |
Ki = 120 nM
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CP0468618
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1-(4-fluorophenyl)imino-3-[2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl]urea
Show/Hide
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C20H24FN5O2
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1
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| 1 |
Ki = 120 nM
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CP0536405
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1-(N-benzyl-4-methoxyanilino)-3-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]urea
Show/Hide
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C29H37N5O3
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1
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| 1 |
Ki = 120 nM
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CP0389478
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(4aR,12bR)-4-propyl-2,3,4a,5,6,8,9,12b-octahydroisochromeno[6,7-h][1,4]benzoxazin-11-one
Show/Hide
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C18H23NO3
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1
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| 1 |
Ki = 120.23 nM
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CP0321300
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N-[4-[4-(2-fluorophenyl)piperazin-1-yl]butyl]-5-phenylpyridin-2-amine
Show/Hide
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C25H29FN4
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1
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| 1 |
Ki = 122 nM
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CP0309750
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N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]-3-methylbutanamide
Show/Hide
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C20H33N3O2
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1
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| 1 |
Ki = 123 nM
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CP0404440
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(4aR,11bR)-4-(2-methylpropyl)-2,3,4a,5,6,8,9,11b-octahydro-[1]benzofuro[5,6-h][1,4]benzoxazine
Show/Hide
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C18H25NO2
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1
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| 1 |
Ki = 125.89 nM
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CP0543609
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4-bromo-1-ethoxy-N-[2-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]ethyl]naphthalene-2-carboxamide
Show/Hide
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C26H27BrF3N3O2
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1
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| 1 |
Ki = 125.89 nM
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CP0508206
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2-benzyl-3,3a,4,9b-tetrahydro-1H-chromeno[3,4-c]pyrrole
Show/Hide
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C18H19NO
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1
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| 1 |
Ki = 125.89 nM
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CP0432497
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4-phenyl-N-[4-[propyl(5,6,7,8-tetrahydroquinazolin-6-yl)amino]butyl]benzamide
Show/Hide
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C28H34N4O
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1
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| 1 |
Ki = 125.89 nM
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CP0381961
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[2-[4-[(3-phenylbenzoyl)amino]butyl]-3,4-dihydro-1H-isoquinolin-7-yl] trifluoromethanesulfonate
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C27H27F3N2O4S
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1
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| 1 |
Ki = 125.89 nM
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CP0086894
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1-(1-benzofuran-5-yl)-3-[2-(1,3-dihydroisoindol-2-yl)ethyl]imidazolidin-2-one
Show/Hide
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C21H21N3O2
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1
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| 1 |
Ki = 125.89 nM
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CP0086896
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1-[(3-chlorophenyl)methyl]-3-[2-(1,3-dihydroisoindol-2-yl)ethyl]imidazolidin-2-one
Show/Hide
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C20H22ClN3O
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1
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| 1 |
Ki = 125.89 nM
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CP0151638
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1-(1-benzothiophen-3-yl)-3-[2-(1,3-dihydroisoindol-2-yl)ethyl]imidazolidin-2-one
Show/Hide
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C21H21N3OS
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1
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| 1 |
Ki = 125.89 nM
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CP0276134
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2-fluoro-5-[2-oxo-3-[2-(4-propan-2-ylpiperazin-1-yl)ethyl]imidazolidin-1-yl]benzonitrile
Show/Hide
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C19H26FN5O
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1
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| 1 |
Ki = 125.89 nM
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CP0049019
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1-(3-chlorophenyl)-3-[2-[2-(3-methoxyphenyl)ethyl-methylamino]ethyl]imidazolidin-2-one
Show/Hide
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C21H26ClN3O2
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1
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| 1 |
Ki = 125.89 nM
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CP0071305
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1-(3-chlorophenyl)-3-[2-[2-(3,4-dimethoxyphenyl)ethyl-methylamino]ethyl]imidazolidin-2-one
Show/Hide
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C22H28ClN3O3
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1
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| 1 |
Ki = 125.89 nM
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CP0092519
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1-(3-chlorophenyl)-3-[2-[methyl-[(3-methyl-1,2-oxazol-5-yl)methyl]amino]ethyl]imidazolidin-2-one
Show/Hide
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C17H21ClN4O2
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1
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| 1 |
Ki = 125.89 nM
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CP0441267
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1-Methyl-2-((4-phenylpiperidin-1-yl)methyl)-1H-benzo[d]-imidazole
Show/Hide
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C20H23N3
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1
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| 1 |
Ki = 125.89 nM
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CP0308461
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4-methyl-5-[4-methyl-5-[3-(1-phenyl-3-azabicyclo[4.1.0]heptan-3-yl)propylsulfanyl]-1,2,4-triazol-3-yl]-1,3-oxazole
Show/Hide
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C22H27N5OS
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1
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| 1 |
Ki = 125.89 nM
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CP0380756
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2-[(4S,5R)-9-(benzenesulfonyl)-5-(dimethylamino)-9-azatricyclo[6.3.0.03,6]undeca-1,3(6),7,10-tetraen-4-yl]ethanol
Show/Hide
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C20H22N2O3S
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1
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| 1 |
Ki = 125.89 nM
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CP0378035
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N-[4-[4-(1H-indazol-3-yl)piperazin-1-yl]butyl]-7-methoxy-1-benzofuran-2-carboxamide
Show/Hide
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C25H29N5O3
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1
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| 1 |
Ki = 127 nM
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CP0060239
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N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]benzamide
Show/Hide
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C22H29N3O2
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1
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| 1 |
Ki = 128 nM
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CP0240527
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2-(4-{3-[4-(4-Methoxy-phenyl)-piperazin-1-yl]-propoxy}-phenyl)-1H-benzoimidazole
Show/Hide
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C27H30N4O2
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1
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| 1 |
Ki = 130 nM
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CP0438114
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1-(N-benzyl-4-bromoanilino)-3-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]urea
Show/Hide
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C28H34BrN5O2
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1
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| 1 |
Ki = 130 nM
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CP0468622
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1-(N-benzyl-4-chloroanilino)-3-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]urea
Show/Hide
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C28H34ClN5O2
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1
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| 1 |
Ki = 130 nM
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CP0505180
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(3-{4-[1-(6-{2-[4-(3-Diethylamino-propoxy)-phenyl]-benzoimidazol-1-yl}-hexyl)-1H-benzoimidazol-2-yl]-phenoxy}-propyl)-diethyl-amine
Show/Hide
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C46H60N6O2
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1
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| 1 |
Ki = 131 nM
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CP0210362
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(R)-3-(1-Propyl-piperidin-3-yl)-phenol
Show/Hide
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C14H21NO
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1
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| 1 |
Ki = 132 nM
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CP0464370
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N,N-diethyl-3-[4-[1-[(E)-4-(2-phenylbenzimidazol-1-yl)but-2-enyl]benzimidazol-2-yl]phenoxy]propan-1-amine
Show/Hide
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C37H39N5O
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1
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| 1 |
Ki = 133 nM
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CP0513759
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2-[4-(4-benzhydryl-1,4-diazepan-1-yl)butyl]isoindole-1,3-dione
Show/Hide
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C30H33N3O2
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1
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| 1 |
Ki = 133 nM
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CP0350789
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N-[4-[4-(2-fluorophenyl)piperazin-1-yl]butyl]pyridin-2-amine
Show/Hide
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C19H25FN4
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1
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| 1 |
Ki = 133 nM
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CP0389515
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N-[4-[cyclohexyl(propyl)amino]butyl]-4-phenylbenzamide
Show/Hide
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C26H36N2O
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1
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| 1 |
Ki = 140 nM
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CP0868271
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N-{3-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-propyl}-2-naphthalen-2-yl-acetamide oxalic acid
Show/Hide
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C28H33N3O6
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1
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| 1 |
Ki = 140 nM
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CP0172628
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1-Phenyl-4-[(1-phenyl-1H-pyrazol-4-yl)methyl]piperazine
Show/Hide
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C20H22N4
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2
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| 1 |
Ki = 140 nM
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| 2 |
Ki = 141.25 nM
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CP0853881
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4-(4-(4-Chlorophenyl)-4-hydroxypiperidin-1-yl)-1-(4-(2-((2-hydroxyethyl)disulfanyl)ethoxy)phenyl)butan-1-one formic acid
Show/Hide
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C26H34ClNO6S2
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1
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| 1 |
Ki = 140 nM
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CP0438116
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1-(4-fluorophenyl)imino-3-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]urea
Show/Hide
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C21H26FN5O2
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1
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| 1 |
Ki = 140 nM
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CP0297520
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5-phenyl-N-(4-(4-(3-(trifluoromethyl)phenyl)piperazin-1-yl)butyl)pyridin-2-amine
Show/Hide
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C26H29F3N4
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1
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| 1 |
Ki = 143 nM
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CP0442287
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(3-{4-[1-((E)-4-{2-[4-(3-Dimethylamino-propoxy)-phenyl]-benzoimidazol-1-yl}-but-2-enyl)-1H-benzoimidazol-2-yl]-phenoxy}-propyl)-dimethyl-amine
Show/Hide
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C40H46N6O2
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1
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| 1 |
Ki = 144 nM
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CP0437726
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N-methyl-N-[[4-(3-piperidin-1-ylpropoxy)phenyl]methyl]-3-(1-tetracyclo[6.6.2.02,7.09,14]hexadeca-2,4,6,9,11,13-hexaenyl)propan-1-amine
Show/Hide
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C35H44N2O
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1
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| 1 |
Ki = 149 nM
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CP0154475
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3-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-1H-indole
Show/Hide
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C19H20ClN3
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1
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| 1 |
Ki = 150 nM
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CP0474566
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4-(2-phenylethynyl)-N-[4-[4-(4-phenylphenyl)triazol-1-yl]butyl]-N-propylcyclohex-3-en-1-amine
Show/Hide
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C35H38N4
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1
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| 1 |
Ki = 150 nM
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CP0100739
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N-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]pyrazolo[1,5-a]pyridine-3-carboxamide
Show/Hide
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C22H27N5O2
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1
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| 1 |
Ki = 150 nM
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CP0438121
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1-[4-fluoro-N-[(3-methoxyphenyl)methyl]anilino]-3-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]urea
Show/Hide
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C29H36FN5O3
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1
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| 1 |
Ki = 150 nM
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CP0430226
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4-[5-methoxy-3-(1,2,3,6-tetrahydropyridin-4-yl)indol-1-yl]sulfonylisoquinoline
Show/Hide
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C23H21N3O3S
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1
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| 1 |
Ki = 150 nM
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CP0121123
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2-(4-{3-[4-(3-Chloro-phenyl)-piperazin-1-yl]-propoxy}-phenyl)-1H-benzoimidazole
Show/Hide
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C26H27ClN4O
|
1
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| 1 |
Ki = 155 nM
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CP0324171
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1-phenyl-4-((1-(pyridin-2-yl)-1H-pyrazol-4-yl)methyl)piperazine
Show/Hide
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C19H21N5
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2
|
| 1 |
Ki = 158.49 nM
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| 2 |
Ki = 160 nM
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CP0086897
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1-[(2,5-dichlorophenyl)methyl]-3-[2-(1,3-dihydroisoindol-2-yl)ethyl]imidazolidin-2-one
Show/Hide
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C20H21Cl2N3O
|
1
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| 1 |
Ki = 158.49 nM
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CP0097605
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1-(3-chloro-2-fluorophenyl)-3-[2-(4-propan-2-ylpiperazin-1-yl)ethyl]imidazolidin-2-one
Show/Hide
|
C18H26ClFN4O
|
1
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| 1 |
Ki = 158.49 nM
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CP0267612
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1-[(4-chlorophenyl)methyl]-3-[2-(1,3-dihydroisoindol-2-yl)ethyl]imidazolidin-2-one
Show/Hide
|
C20H22ClN3O
|
1
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| 1 |
Ki = 158.49 nM
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CP0307028
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1-(3-chlorophenyl)-3-[2-(4-methylpiperazin-1-yl)ethyl]imidazolidin-2-one
Show/Hide
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C16H23ClN4O
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1
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| 1 |
Ki = 158.49 nM
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CP0338077
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1-(3-methoxyphenyl)-3-[2-(4-propan-2-ylpiperazin-1-yl)ethyl]imidazolidin-2-one
Show/Hide
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C19H30N4O2
|
1
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| 1 |
Ki = 158.49 nM
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CP0197709
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1-(3-chlorophenyl)-3-[2-[(1R,5S)-8-(methoxymethyl)-3-azabicyclo[3.2.1]octan-3-yl]ethyl]imidazolidin-2-one
Show/Hide
|
C20H28ClN3O2
|
1
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| 1 |
Ki = 158.49 nM
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CP0226511
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1-(3-chlorophenyl)-3-[2-[4-(5-phenyl-1,3,4-oxadiazol-2-yl)piperidin-1-yl]ethyl]imidazolidin-2-one
Show/Hide
|
C24H26ClN5O2
|
1
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| 1 |
Ki = 158.49 nM
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CP0042185
|
4-methyl-5-[4-methyl-5-[3-(6-phenyl-3-azabicyclo[4.1.0]heptan-3-yl)propylsulfanyl]-1,2,4-triazol-3-yl]-1,3-oxazole
Show/Hide
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C22H27N5OS
|
1
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| 1 |
Ki = 158.49 nM
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CP0333692
|
5-[5-[3-(6-fluorospiro[1,2-dihydroindene-3,3'-pyrrolidine]-1'-yl)propylsulfanyl]-4-methyl-1,2,4-triazol-3-yl]-4-methyl-1,3-oxazole
Show/Hide
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C22H26FN5OS
|
1
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| 1 |
Ki = 158.49 nM
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CP0401196
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N-(1-benzylpiperidin-4-yl)-5-chloro-2-methoxy-4-(methylamino)benzamide
Show/Hide
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C21H26ClN3O2
|
1
|
| 1 |
Ki = 160 nM
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CP0385451
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5-(2-ethoxyethoxymethyl)-N-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]pyrazolo[1,5-a]pyridine-3-carboxamide
Show/Hide
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C27H37N5O4
|
1
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| 1 |
Ki = 160 nM
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CP0488643
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1-(2-methoxyphenyl)-4-[[3-(piperidin-1-ylmethyl)azulen-1-yl]methyl]piperazine
Show/Hide
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C28H35N3O
|
1
|
| 1 |
Ki = 160 nM
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CP0480635
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bis[4-(4-chlorophenyl)-1-[4-(4-fluorophenyl)-4-oxobutyl]piperidin-4-yl] tetradecanedioate
Show/Hide
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C56H68Cl2F2N2O6
|
1
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| 1 |
Ki = 160 nM
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CP0423181
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5-hydroxy-8-piperazin-1-yl-4H-1,4-benzoxazin-3-one
Show/Hide
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C12H15N3O3
|
1
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| 1 |
Ki = 160 nM
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CP0482776
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1-[4-fluoro-N-[(2-fluorophenyl)methyl]anilino]-3-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]urea
Show/Hide
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C28H33F2N5O2
|
1
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| 1 |
Ki = 160 nM
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CP0918977
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1-[4-(3-Thiophen-2-yl-isoxazol-5-yl)-butyl]-4-o-tolyl-piperazine hydrochloride
Show/Hide
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C22H28ClN3OS
|
1
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| 1 |
Ki = 163 nM
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CP0859228
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(2H-Benzo[1,4]oxazin-3-yl)-[5-(4-phenyl-piperazin-1-yl)-pentyl]-amine hydrobromide
Show/Hide
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C23H31BrN4O
|
1
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| 1 |
Ki = 167 nM
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CP0453211
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2-(1H-Pyrrolo[2,3-b]pyridin-3-ylmethyl)-1,2,3,4-tetrahydro-isoquinoline
Show/Hide
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C17H17N3
|
1
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| 1 |
Ki = 170 nM
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CP0053618
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4-Amino-N-(1-benzyl-piperidin-4-yl)-5-chloro-2-methoxy-benzamide
Show/Hide
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C20H24ClN3O2
|
1
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| 1 |
Ki = 170 nM
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CP0467632
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3-(2-ethoxyethoxy)-N-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]benzamide
Show/Hide
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C25H35N3O4
|
1
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| 1 |
Ki = 170 nM
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CP0239544
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1-(N-benzylanilino)-3-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]urea
Show/Hide
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C28H35N5O2
|
1
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| 1 |
Ki = 170 nM
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CP0393162
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3-[2-[4-[(E)-2-phenylethenyl]-3,6-dihydro-2H-pyridin-1-yl]ethyl]-1H-pyrrolo[2,3-b]pyridine
Show/Hide
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C22H23N3
|
1
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| 1 |
Ki = 180 nM
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CP0080249
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4-[4-(4-Chloro-phenyl)-piperazin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one; hydrochloride
Show/Hide
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C20H22ClFN2O
|
1
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| 1 |
Ki = 180 nM
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CP0502796
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(3-{4-[1-(4-{2-[4-(3-Diethylamino-propoxy)-phenyl]-benzoimidazol-1-ylmethyl}-benzyl)-1H-benzoimidazol-2-yl]-phenoxy}-propyl)-diethyl-amine
Show/Hide
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C48H56N6O2
|
1
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| 1 |
Ki = 184 nM
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CP0240252
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N-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl]-4-phenylpyridin-2-amine
Show/Hide
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C25H28Cl2N4
|
1
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| 1 |
Ki = 184 nM
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CP0371907
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2-(4-(4-phenyl-1-piperazinyl)butyl)-1,2-benzisothiazole-3(2H)-one 1,1-dioxide
Show/Hide
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C22H27N3O4S
|
1
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| 1 |
Ki = 187 nM
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CP0534303
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1-[4-[2-[(5R)-7-chloro-5-methyl-1,2,4,5-tetrahydro-3-benzazepin-3-yl]ethyl]cyclohexyl]pyrrolidine-2,5-dione
Show/Hide
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C23H31ClN2O2
|
1
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| 1 |
Ki = 190.7 nM
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CP0403535
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1-Phenyl-4-(2-phenyl-3H-imidazol-4-ylmethyl)-piperazine
Show/Hide
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C20H22N4
|
1
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| 1 |
Ki = 193 nM
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CP0329826
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4-phenyl-N-(4-(4-(3-(trifluoromethyl)phenyl)piperazin-1-yl)butyl)pyridin-2-amine
Show/Hide
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C26H29F3N4
|
1
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| 1 |
Ki = 194 nM
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CP0533143
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3-[4-[2-[(5S)-7-chloro-5-methyl-1,2,4,5-tetrahydro-3-benzazepin-3-yl]ethyl]cyclohexyl]-1,1-dimethylurea
Show/Hide
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C22H34ClN3O
|
1
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| 1 |
Ki = 194.8 nM
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CP0424211
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1-(4-(4-phenyl-1-piperazinyl)butyl)indolin-2-one
Show/Hide
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C23H29N3O2
|
1
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| 1 |
Ki = 195 nM
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CP0321299
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N-[4-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]butyl]pyridin-2-amine
Show/Hide
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C20H25F3N4
|
1
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| 1 |
Ki = 198 nM
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CP0370155
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N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]pyridin-2-amine
Show/Hide
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C20H28N4O
|
1
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| 1 |
Ki = 198 nM
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CP0494849
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(4aR,11bR)-3,4,4a,5,6,8,9,11b-octahydro-2H-[1]benzofuro[5,6-h][1,4]benzoxazine
Show/Hide
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C14H17NO2
|
1
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| 1 |
Ki = 199.53 nM
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CP0425040
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4-bromo-N-[2-[4-(2,4-difluorophenyl)piperazin-1-yl]ethyl]-1-methoxynaphthalene-2-carboxamide
Show/Hide
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C24H24BrF2N3O2
|
1
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| 1 |
Ki = 199.53 nM
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CP0526713
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4-bromo-N-[2-[4-(3,4-dichlorophenyl)piperazin-1-yl]ethyl]-1-methoxynaphthalene-2-carboxamide
Show/Hide
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C24H24BrCl2N3O2
|
1
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| 1 |
Ki = 199.53 nM
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CP0517139
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[(4aS,10bS)-4-[4-[(4-phenylbenzoyl)amino]butyl]-2,3,4a,5,6,10b-hexahydro-1H-benzo[f]quinolin-8-yl] methanesulfonate
Show/Hide
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C31H36N2O4S
|
1
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| 1 |
Ki = 199.53 nM
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CP0113176
|
5-Chloro-3-methyl-benzo[b]thiophene-2-sulfonic acid [4-methoxy-3-(4-methyl-piperazin-1-yl)-phenyl]-amide
Show/Hide
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C21H24ClN3O3S2
|
1
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| 1 |
Ki = 199.53 nM
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CP0201571
|
1-[2-(1,3-dihydroisoindol-2-yl)ethyl]-3-(5-methylthiophen-2-yl)imidazolidin-2-one
Show/Hide
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C18H21N3OS
|
1
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| 1 |
Ki = 199.53 nM
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CP0266801
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1-[2-(1,3-dihydroisoindol-2-yl)ethyl]-3-(4-pyridin-2-ylthiophen-3-yl)imidazolidin-2-one
Show/Hide
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C22H22N4OS
|
1
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| 1 |
Ki = 199.53 nM
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CP0433010
|
1-[[1-[4-[2-[2-(2-fluoroethoxy)ethoxy]ethoxy]phenyl]triazol-4-yl]methyl]-4-(2-methoxyphenyl)piperazine
Show/Hide
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C26H34FN5O4
|
1
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| 1 |
Ki = 200 nM
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CP0380143
|
4-bromo-N-[2-[4-[2-(1H-indol-3-yl)ethyl]piperazin-1-yl]ethyl]aniline
Show/Hide
|
C22H27BrN4
|
1
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| 1 |
Ki = 200 nM
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CP0862635
|
4'-(4-(pyrazolo[1,5-a]pyridine-2-carboxamido)butyl)-2,3-dihydrospiro[benzo[b][1,4]oxazine-4,1'-piperazin]-4-ium 4-methylbenzenesulfonate
Show/Hide
|
C31H37N5O5S
|
1
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| 1 |
Ki = 200 nM
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CP0400954
|
(1-Benzyl-piperidin-4-yl)-[2-(5-bromo-2-methoxy-phenyl)-thiazol-4-ylmethyl]-amine
Show/Hide
|
C23H26BrN3OS
|
1
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| 1 |
Ki = 205 nM
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CP0060491
|
10,11-dihydro-5-(gamma-dimethylaminopropylidene)-5H-dibenzo(a,d)cycloheptene
Show/Hide
|
C20H23N
|
1
|
| 1 |
Ki = 206 nM
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CP0277804
|
N-[4-[4-(2,3-dimethylphenyl)piperazin-1-yl]butyl]pyridin-2-amine
Show/Hide
|
C21H30N4
|
1
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| 1 |
Ki = 207 nM
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CP0409818
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7-(4-p-Tolyl-piperazin-1-ylmethyl)-4H-benzo[1,4]oxazin-3-one
Show/Hide
|
C20H23N3O2
|
1
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| 1 |
Ki = 208 nM
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CP0393152
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4-Fluoro-N-{4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-butyl}-benzenesulfonamide
Show/Hide
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C21H28FN3O3S
|
1
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| 1 |
Ki = 210 nM
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CP0428803
|
1-(2-methoxyphenyl)-4-[[3-(2-phenylethynyl)azulen-1-yl]methyl]piperazine
Show/Hide
|
C30H28N2O
|
1
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| 1 |
Ki = 210 nM
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CP0385669
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bis[4-(4-chlorophenyl)-1-[4-(4-fluorophenyl)-4-oxobutyl]piperidin-4-yl] dodecanedioate
Show/Hide
|
C54H64Cl2F2N2O6
|
1
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| 1 |
Ki = 210 nM
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CP0857263
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1-(1-(2-((2-Azidoethyl)disulfanyl)ethyl)-1H-1,2,3-triazol-4-yl)-4-(4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl)butan-1-one trifluoroacetic acid
Show/Hide
|
C23H29ClF3N7O4S2
|
1
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| 1 |
Ki = 210 nM
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CP0860233
|
2-Iodo-N-{3-[4-(2-methoxy-phenyl)-piperazin-1-yl]-propyl}-benzamide oxalic acid
Show/Hide
|
C23H28IN3O6
|
1
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| 1 |
Ki = 213 nM
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CP0383910
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1-(1-benzylpyrrolidin-3-yl)-N-[[2-(5-bromo-2-methoxyphenyl)-1,3-thiazol-4-yl]methyl]methanamine
Show/Hide
|
C23H26BrN3OS
|
1
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| 1 |
Ki = 220 nM
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CP0508249
|
N-[4-[4-(5-methoxy-1,2-benzoxazol-3-yl)piperazin-1-yl]butyl]quinoxaline-6-carboxamide
Show/Hide
|
C25H28N6O3
|
1
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| 1 |
Ki = 220 nM
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CP0473628
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1-[[3-methoxy-4-[3-[1-[8-[4-[3-[2-methoxy-4-[[4-(2-methoxyphenyl)piperazin-1-yl]methyl]phenoxy]propyl]triazol-1-yl]octyl]triazol-4-yl]propoxy]phenyl]methyl]-4-methylpiperazine
Show/Hide
|
C50H72N10O5
|
1
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| 1 |
Ki = 220 nM
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CP0385670
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bis[4-(4-chlorophenyl)-1-[4-(4-fluorophenyl)-4-oxobutyl]piperidin-4-yl] hexadecanedioate
Show/Hide
|
C58H72Cl2F2N2O6
|
1
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| 1 |
Ki = 220 nM
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CP0438119
|
1-[N-[(4-cyanophenyl)methyl]-4-methoxyanilino]-3-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]urea
Show/Hide
|
C30H36N6O3
|
1
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| 1 |
Ki = 220 nM
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CP0502173
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8-Chloro-11-{4-[4-(3-piperidin-1-yl-propoxy)-benzyl]-piperazin-1-yl}-5H-dibenzo[b,e][1,4]diazepine
Show/Hide
|
C32H38ClN5O
|
1
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| 1 |
Ki = 223 nM
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CP0375473
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1-(2-methoxyphenyl)-4-[[3-methoxy-4-[3-[1-[8-(4-propyltriazol-1-yl)octyl]triazol-4-yl]propoxy]phenyl]methyl]piperazine
Show/Hide
|
C37H54N8O3
|
1
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| 1 |
Ki = 230 nM
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CP0393325
|
7-(4-p-Tolyl-piperidin-1-ylmethyl)-4H-benzo[1,4]oxazin-3-one
Show/Hide
|
C21H24N2O2
|
1
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| 1 |
Ki = 232 nM
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CP0393652
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7-[4-[4-(8-hydroxy-2-oxochromen-5-yl)-1,4-diazepan-1-yl]butoxy]-3,4-dihydro-1H-quinolin-2-one
Show/Hide
|
C27H31N3O5
|
1
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| 1 |
Ki = 240 nM
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CP0491777
|
N-methyl-4-(3-piperidin-1-ylpropoxy)-N-[3-(2-tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,11,13-hexaenylidene)propyl]benzamide
Show/Hide
|
C34H40N2O2
|
1
|
| 1 |
Ki = 243 nM
|
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CP0371914
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1-(4-(4-(3-a,a,a-trifluorotolyl)-1-piperazinyl)butyl)-indolin-2-one
Show/Hide
|
C23H26F3N3O
|
1
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| 1 |
Ki = 247 nM
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CP0402749
|
(+)-3-(1-Propyl-piperidin-3-yl)-benzonitrile
Show/Hide
|
C15H20N2
|
1
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| 1 |
Ki = 249 nM
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CP0402244
|
2-(4-Phenethyl-piperidin-1-ylmethyl)-1H-pyrrolo[2,3-b]pyridine
Show/Hide
|
C21H25N3
|
1
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| 1 |
Ki = 250 nM
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CP0460184
|
1-[[4-[3-[1-(2-ethoxyethyl)triazol-4-yl]propoxy]-3-methoxyphenyl]methyl]-4-(2-methoxyphenyl)piperazine
Show/Hide
|
C28H39N5O4
|
1
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| 1 |
Ki = 250 nM
|
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CP0375584
|
3-Methoxy-5,8,13,13a-tetrahydro-6H-isoquino[3,2-a]isoquinoline
Show/Hide
|
C18H19NO
|
1
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| 1 |
Ki = 251 nM
|
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CP0409152
|
4-bromo-1-methoxy-N-[2-(4-quinolin-2-ylpiperazin-1-yl)ethyl]naphthalene-2-carboxamide
Show/Hide
|
C27H27BrN4O2
|
1
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| 1 |
Ki = 251.19 nM
|
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CP0430382
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4-bromo-1-methoxy-N-[2-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]ethyl]naphthalene-2-carboxamide
Show/Hide
|
C25H25BrF3N3O2
|
1
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| 1 |
Ki = 251.19 nM
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CP0496913
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4-Bromo-1-ethoxy-naphthalene-2-carboxylic acid [2-(4-phenyl-piperazin-1-yl)-ethyl]-amide
Show/Hide
|
C25H28BrN3O2
|
1
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| 1 |
Ki = 251.19 nM
|
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CP0531906
|
4-Bromo-1-methoxy-naphthalene-2-carboxylic acid [2-(4-p-tolyl-piperazin-1-yl)-ethyl]-amide
Show/Hide
|
C25H28BrN3O2
|
1
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| 1 |
Ki = 251.19 nM
|
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CP0377353
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N-[4-[(4aS,10bR)-2,3,4a,5,6,10b-hexahydro-1H-benzo[f]quinolin-4-yl]butyl]-4-phenylbenzamide
Show/Hide
|
C30H34N2O
|
1
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| 1 |
Ki = 251.19 nM
|
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CP0463765
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[(4aS,10bR)-4-[4-[(4-phenylbenzoyl)amino]butyl]-2,3,4a,5,6,10b-hexahydro-1H-benzo[f]quinolin-7-yl] methanesulfonate
Show/Hide
|
C31H36N2O4S
|
1
|
| 1 |
Ki = 251.19 nM
|
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CP0171882
|
N-[2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl]pyrazolo[1,5-a]pyridine-2-carboxamide
Show/Hide
|
C21H25N5O2
|
1
|
| 1 |
Ki = 251.19 nM
|
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CP0040250
|
2-[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]ethanol
Show/Hide
|
C21H25N3O2S
|
1
|
| 1 |
Ki = 251.19 nM
|
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CP0276132
|
1-[2-(1,3-dihydroisoindol-2-yl)ethyl]-3-(2-methyl-1,3-benzothiazol-5-yl)imidazolidin-2-one
Show/Hide
|
C21H22N4OS
|
1
|
| 1 |
Ki = 251.19 nM
|
|
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CP0105801
|
(2S,5S)-N-[3-[[4-methyl-5-(4-methyl-1,3-oxazol-5-yl)-1,2,4-triazol-3-yl]sulfanyl]propyl]-5-[4-(trifluoromethyl)phenyl]bicyclo[3.1.0]hexan-2-amine
Show/Hide
|
C23H26F3N5OS
|
1
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| 1 |
Ki = 251.19 nM
|
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CP0399599
|
2-[(4S,5R)-9-(benzenesulfonyl)-5-(methylamino)-9-azatricyclo[6.3.0.03,6]undeca-1,3(6),7,10-tetraen-4-yl]ethanol
Show/Hide
|
C19H20N2O3S
|
1
|
| 1 |
Ki = 251.19 nM
|
|
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CP0414404
|
N-methyl-1-(3-naphthalen-1-ylsulfonyl-6,7-dihydrocyclobuta[e]indol-7-yl)methanamine
Show/Hide
|
C22H20N2O2S
|
1
|
| 1 |
Ki = 251.19 nM
|
|
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CP0037227
|
7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-ol
Show/Hide
|
C16H25NO
|
1
|
| 1 |
Ki = 259 nM
|
|
|
|
CP0916146
|
2-(6-Methoxy-naphthalen-2-yl)-N-{3-[4-(2-methoxy-phenyl)-piperazin-1-yl]-propyl}-propionamide oxalic acid
Show/Hide
|
C30H37N3O7
|
1
|
| 1 |
Ki = 262 nM
|
|
|
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CP0515941
|
7-methoxy-N-(4-(4-(quinoxalin-5-yl)piperazin-1-yl)butyl)benzofuran-2-carboxamide
Show/Hide
|
C26H29N5O3
|
1
|
| 1 |
Ki = 262 nM
|
|
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CP0165177
|
Benzyl-(2-trifluoromethyl-3,6,7,8-tetrahydro-chromeno[7,8-d]imidazol-8-ylmethyl)-amine
Show/Hide
|
C19H18F3N3O
|
1
|
| 1 |
Ki = 263 nM
|
|
|
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CP0853784
|
2,2,2-Trichloro-1-((S)-7-dipropylamino-5,6,7,8-tetrahydro-indolizin-3-yl)-ethanone
Show/Hide
|
C16H23Cl3N2O
|
1
|
| 1 |
Ki = 263.03 nM
|
|
|
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CP0453469
|
7-(4-Benzyl-piperazin-1-yl)-3-[4-(4-chloro-phenyl)-piperazin-1-ylmethyl]-2-methyl-pyrazolo[1,5-a]pyridine
Show/Hide
|
C30H35ClN6
|
1
|
| 1 |
Ki = 270 nM
|
|
|
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CP0385666
|
[4-(4-chlorophenyl)-1-[4-(4-fluorophenyl)-4-oxobutyl]piperidin-4-yl] 4-methylbenzoate
Show/Hide
|
C29H29ClFNO3
|
1
|
| 1 |
Ki = 270 nM
|
|
|
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CP0522316
|
2-[4-[3-(4-phenylpiperazin-1-yl)propoxy]phenyl]-1-[(E)-4-[2-[4-[3-(4-phenylpiperazin-1-yl)propoxy]phenyl]benzimidazol-1-yl]but-2-enyl]benzimidazole
Show/Hide
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C56H60N8O2
|
1
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| 1 |
Ki = 275 nM
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CP0103405
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3-(4-Phenyl-piperazin-1-ylmethyl)-1H-indole
Show/Hide
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C19H21N3
|
1
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| 1 |
Ki = 280 nM
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CP0389513
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N-[4-(4-methyltriazol-1-yl)butyl]-N-propyl-4-prop-1-ynylcyclohex-3-en-1-amine
Show/Hide
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C19H30N4
|
1
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| 1 |
Ki = 280 nM
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CP0473501
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1-(2,5-Dimethylphenyl)-4-[4-(2,5-dimethylphenyl)-4-hydroxypiperidin-1-yl]butan-1-one
Show/Hide
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C25H33NO2
|
1
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| 1 |
Ki = 280 nM
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CP0410999
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N-[2-[4-[2-(1H-indol-3-yl)ethyl]piperazin-1-yl]ethyl]-4-methoxy-N-propylaniline
Show/Hide
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C26H36N4O
|
1
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| 1 |
Ki = 280 nM
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CP0429287
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1-[2,4-dichloro-N-[(4-cyanophenyl)methyl]anilino]-3-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]urea
Show/Hide
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C29H32Cl2N6O2
|
1
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| 1 |
Ki = 280 nM
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CP0432841
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2-(2-Benzylamino-ethoxy)-phenol
Show/Hide
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C15H17NO2
|
1
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| 1 |
Ki = 281.5 nM
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CP0424213
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2-(4-(4-(4-chlorophenyl)-1-piperazinyl)butyl)-1,2-benzisothiazole-3(2H)-one 1,1-dioxide
Show/Hide
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C21H24ClN3O3S
|
1
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| 1 |
Ki = 287 nM
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CP0404616
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1-(2-Phenyl-3H-imidazol-4-ylmethyl)-4-pyridin-3-yl-piperazine
Show/Hide
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C19H21N5
|
1
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| 1 |
Ki = 289 nM
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CP0405923
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4-[4-(4-Chlorophenyl)piperazin-1-yl]-1-(2,5-dimethylphenyl)-butan-1-one
Show/Hide
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C23H28ClNO
|
1
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| 1 |
Ki = 290 nM
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CP0544077
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4-phenyl-8-(3-pyrrolidin-1-ylpropoxy)-5H-indeno[1,2-d]pyrimidin-2-amine
Show/Hide
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C24H26N4O
|
1
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| 1 |
Ki = 290 nM
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CP0890625
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1-[4-(3-Phenyl-isoxazol-5-yl)-butyl]-4-o-tolyl-piperazine hydrochloride
Show/Hide
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C24H30ClN3O
|
1
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| 1 |
Ki = 292 nM
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CP0392163
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5-(1,2,4,4a,5,6-Hexahydro-pyrazino[1,2-a]quinolin-3-yl)-1-phenyl-pentan-1-one
Show/Hide
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C23H28N2O
|
1
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| 1 |
Ki = 297 nM
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CP0474504
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4-phenyl-N-[4-[[4-(2-phenylethynyl)cyclohex-3-en-1-yl]-propylamino]butyl]benzamide
Show/Hide
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C34H38N2O
|
1
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| 1 |
Ki = 300 nM
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CP0916109
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3-Iodo-N-{3-[4-(2-methoxy-phenyl)-piperazin-1-yl]-propyl}-benzamide oxalic acid
Show/Hide
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C23H28IN3O6
|
1
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| 1 |
Ki = 300 nM
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CP0371909
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3-(4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl)quinazolin-4(3H)-one
Show/Hide
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C23H28N4O2
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1
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| 1 |
Ki = 306 nM
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CP0430707
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5,8,13,13a-Tetrahydro-6H-isoquino[3,2-a]isoquinolin-3-ol
Show/Hide
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C17H17NO
|
1
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| 1 |
Ki = 306.5 nM
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CP0297521
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N-[4-[4-(2-fluorophenyl)piperazin-1-yl]butyl]-4-phenylpyridin-2-amine
Show/Hide
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C25H29FN4
|
1
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| 1 |
Ki = 309 nM
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CP0316181
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3-Methyl-7-[(4-pyridin-2-ylpiperazin-1-yl)methyl]-2-pyrrolidin-1-yl-3,5-dihydro-4H-pyrrolo[3,2-d]pyrimidin-4-one
Show/Hide
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C21H27N7O
|
1
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| 1 |
Ki = 310 nM
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CP0148103
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1-[N-[(4-fluorophenyl)methyl]anilino]-3-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]urea
Show/Hide
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C28H34FN5O2
|
1
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| 1 |
Ki = 310 nM
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CP0448809
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4-Bromo-1-methoxy-naphthalene-2-carboxylic acid [2-(4-m-tolyl-piperazin-1-yl)-ethyl]-amide
Show/Hide
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C25H28BrN3O2
|
1
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| 1 |
Ki = 316.23 nM
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CP0498769
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5-bromo-2-methoxy-N-[2-(4-phenylpiperazin-1-yl)ethyl]benzamide
Show/Hide
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C20H24BrN3O2
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1
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| 1 |
Ki = 316.23 nM
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CP0534263
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4-bromo-3-methoxy-N-[2-(4-phenylpiperazin-1-yl)ethyl]naphthalene-2-carboxamide
Show/Hide
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C24H26BrN3O2
|
1
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| 1 |
Ki = 316.23 nM
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CP0183577
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5-Chloro-3-methyl-benzo[b]thiophene-2-sulfonic acid ((S)-3-hexahydro-pyrrolo[1,2-a]pyrazin-2-yl-4-methoxy-phenyl)-amide
Show/Hide
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C23H26ClN3O3S2
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1
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| 1 |
Ki = 316.23 nM
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CP0422138
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2-[[4-(4-chlorophenyl)piperidin-1-yl]methyl]-1-methylbenzimidazole
Show/Hide
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C20H22ClN3
|
1
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| 1 |
Ki = 316.23 nM
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CP0405095
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3-[[4-[2-(2-fluoroethoxy)phenyl]piperazin-1-yl]methyl]pyrazolo[1,5-a]pyridine
Show/Hide
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C20H23FN4O
|
1
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| 1 |
Ki = 320 nM
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CP0858090
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1-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-3-phenyl-pyrrole-2,5-dione oxalic acid
Show/Hide
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C27H31N3O7
|
1
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| 1 |
Ki = 320 nM
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CP0051889
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1-((5-methyl-1-phenyl-1H-pyrazol-4-yl)methyl)-4-phenylpiperazine
Show/Hide
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C21H24N4
|
2
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| 1 |
Ki = 320 nM
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| 2 |
Ki = 323.59 nM
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CP0046179
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N-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl]-1-(4-nitrophenyl)triazole-4-carboxamide
Show/Hide
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C23H25Cl2N7O3
|
1
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| 1 |
Ki = 320 nM
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CP0486215
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1-[[4-[(1-butyltriazol-4-yl)methoxy]-3-methoxyphenyl]methyl]-4-(2-methoxyphenyl)piperazine
Show/Hide
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C26H35N5O3
|
1
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| 1 |
Ki = 320 nM
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CP0468620
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1-[4-methoxy-N-[(3-methoxyphenyl)methyl]anilino]-3-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]urea
Show/Hide
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C30H39N5O4
|
1
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| 1 |
Ki = 320 nM
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CP0436932
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(7aR,10aS)-8-Propyl-7,7a,8,9,10,10a-hexahydro-6H-1-oxa-8-aza-dicyclopenta[a,h]naphthalene
Show/Hide
|
C17H21NO
|
1
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| 1 |
Ki = 323 nM
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CP0505105
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((R)-7-Dipropylamino-5,6,7,8-tetrahydro-indolizin-1-yl)-methanol
Show/Hide
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C15H26N2O
|
2
|
| 1 |
Ki = 323.59 nM
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| 2 |
Ki = 330 nM
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CP0883142
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(R)-7-Dipropylamino-5,6,7,8-tetrahydro-indolizine-3-carboxylic acid ethyl ester
Show/Hide
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C17H28N2O2
|
1
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| 1 |
Ki = 323.59 nM
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CP0496297
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(E)-N-[[2-[[4-(2-methoxyphenyl)piperazin-1-yl]methyl]phenyl]methyl]-3-phenylprop-2-enamide
Show/Hide
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C28H31N3O2
|
1
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| 1 |
Ki = 325 nM
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CP0371972
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N-methyl-2-[4-(3-piperidin-1-ylpropoxy)phenyl]-N-[3-(2-tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,11,13-hexaenylidene)propyl]acetamide
Show/Hide
|
C35H42N2O2
|
1
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| 1 |
Ki = 326 nM
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CP0247839
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3-Methyl-7-[(4-phenylpiperazin-1-yl)methyl]-2-pyrrolidin-1-yl-3,5-dihydro-4H-pyrrolo[3,2-d]pyrimidin-4-one
Show/Hide
|
C22H28N6O
|
1
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| 1 |
Ki = 330 nM
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CP0372554
|
4-(2-ethoxyethoxymethyl)-N-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]benzamide
Show/Hide
|
C26H37N3O4
|
1
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| 1 |
Ki = 330 nM
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CP0445342
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N-[4-(4-benzhydryl-1,4-diazepan-1-yl)butyl]thiophene-2-carboxamide
Show/Hide
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C27H33N3OS
|
1
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| 1 |
Ki = 340 nM
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CP0391220
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1-(2-methoxyphenyl)-4-((1-phenyl-1H-1,2,3-triazol-4-yl)methyl)piperazine
Show/Hide
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C20H23N5O
|
1
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| 1 |
Ki = 340 nM
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CP0395490
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N-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]-4-[2-[2-[2-[2-[2-[2-[2-[2-[[4-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propylcarbamoyl]phenyl]methoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxymethyl]benzamide
Show/Hide
|
C60H88N6O13
|
1
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| 1 |
Ki = 350 nM
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CP0428802
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4-[[3-[[4-(2-methoxyphenyl)piperazin-1-yl]methyl]azulen-1-yl]methyl]morpholine
Show/Hide
|
C27H33N3O2
|
1
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| 1 |
Ki = 350 nM
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CP0930724
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Bis-{5-[4-(2-methoxy-phenyl)-piperazin-1-yl]-octahydro-pentalen-2-yl}-amine oxalic acid
Show/Hide
|
C40H57N5O6
|
1
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| 1 |
Ki = 358 nM
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CP0378752
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1-((3-methyl-1-phenyl-1H-pyrazol-4-yl)methyl)-4-phenylpiperazine
Show/Hide
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C21H24N4
|
2
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| 1 |
Ki = 360 nM
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| 2 |
Ki = 363.08 nM
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CP0079550
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N-[2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl]pyrazolo[1,5-a]pyridine-3-carboxamide
Show/Hide
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C21H25N5O2
|
1
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| 1 |
Ki = 363.08 nM
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CP0544075
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2-amino-4-phenyl-8-(3-piperidin-1-ylpropoxy)indeno[1,2-d]pyrimidin-5-one
Show/Hide
|
C25H26N4O2
|
1
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| 1 |
Ki = 364 nM
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CP0496624
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2-[5-[4-(4-Chlorophenyl)piperazin-1-yl]pentyl]pyrazolo[1,5-a]-pyridine
Show/Hide
|
C22H27ClN4
|
1
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| 1 |
Ki = 370 nM
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CP0414003
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1-(2-methoxyphenyl)-4-[(3-pent-1-ynylazulen-1-yl)methyl]piperazine
Show/Hide
|
C27H30N2O
|
1
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| 1 |
Ki = 370 nM
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CP0414823
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1-[(3-ethynylazulen-1-yl)methyl]-4-(2-methoxyphenyl)piperazine
Show/Hide
|
C24H24N2O
|
1
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| 1 |
Ki = 370 nM
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CP0463610
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bis[4-(4-chlorophenyl)-1-[4-(4-fluorophenyl)-4-oxobutyl]piperidin-4-yl] octadecanedioate
Show/Hide
|
C60H76Cl2F2N2O6
|
1
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| 1 |
Ki = 380 nM
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CP0436856
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8-hydroxy-5-(4-methylpiperazin-1-yl)-1H-quinolin-2-one
Show/Hide
|
C14H17N3O2
|
1
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| 1 |
Ki = 380 nM
|
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CP0350790
|
N-[4-[4-(2-methylphenyl)piperazin-1-yl]butyl]pyridin-2-amine
Show/Hide
|
C20H28N4
|
1
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| 1 |
Ki = 383 nM
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CP0408574
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2-[4-(2-methoxyphenyl)piperazin-1-ylmethyl]-6-methyl-8-phenylimidazo[1,2-a]pyridine
Show/Hide
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C26H28N4O
|
1
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| 1 |
Ki = 390 nM
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CP0381527
|
1-[3-[[4-(2-methoxyphenyl)piperazin-1-yl]methyl]azulen-1-yl]-N,N-dimethylmethanamine
Show/Hide
|
C25H31N3O
|
1
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| 1 |
Ki = 390 nM
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CP0857262
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1-(4-(2-((2-Aminoethyl)disulfanyl)ethoxy)-3-methoxyphenethyl)-4-(4-chlorophenyl)piperidin-4-ol ditrifluoroacetic acid
Show/Hide
|
C28H35ClF6N2O7S2
|
1
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| 1 |
Ki = 390 nM
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CP0441226
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4-Iodo-N-{3-[4-(2-methoxy-phenyl)-piperazin-1-yl]-propyl}-benzamide
Show/Hide
|
C21H26IN3O2
|
1
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| 1 |
Ki = 396 nM
|
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CP0428547
|
3-bromo-2-hydroxy-6-methoxy-N-[2-(4-phenylpiperazin-1-yl)ethyl]benzamide
Show/Hide
|
C20H24BrN3O3
|
1
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| 1 |
Ki = 398.11 nM
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CP0432198
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2-[(4R,5R)-9-(benzenesulfonyl)-4-(dimethylamino)-9-azatricyclo[6.3.0.03,6]undeca-1,3(6),7,10-tetraen-5-yl]ethanol
Show/Hide
|
C20H22N2O3S
|
1
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| 1 |
Ki = 398.11 nM
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CP0419868
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5-hydroxy-8-[(1S)-1-hydroxy-2-[2-[3-methoxy-4-(3-phenylpropoxy)phenyl]ethylamino]ethyl]-4H-1,4-benzoxazin-3-one
Show/Hide
|
C28H32N2O6
|
1
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| 1 |
Ki = 400 nM
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CP0559025
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1-[N-[(4-fluorophenyl)methyl]-4-methoxyanilino]-3-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]urea
Show/Hide
|
C29H36FN5O3
|
1
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| 1 |
Ki = 400 nM
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CP0850057
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(2H-Benzo[1,4]oxazin-3-yl)-[5-(4-pyridin-2-yl-piperazin-1-yl)-pentyl]-amine; compound with but-2-enedioic acid
Show/Hide
|
C26H33N5O5
|
1
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| 1 |
Ki = 408 nM
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CP0403324
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7-(4-Benzyl-piperazin-1-yl)-3-[4-(4-chloro-phenyl)-piperazin-1-ylmethyl]-pyrazolo[1,5-a]pyridine
Show/Hide
|
C29H33ClN6
|
1
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| 1 |
Ki = 410 nM
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CP0427876
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3-[[4-(6-bromopyridin-2-yl)piperazin-1-yl]methyl]pyrazolo[1,5-a]pyridine
Show/Hide
|
C17H18BrN5
|
1
|
| 1 |
Ki = 410 nM
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CP0373606
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4-[4-(4-Chlorophenyl)piperazin-1-yl]-1-([2.2]paracyclophan-4-yl)butan-1-one
Show/Hide
|
C30H33ClN2O
|
1
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| 1 |
Ki = 410 nM
|
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CP0399841
|
((S)-7-Dipropylamino-5,6,7,8-tetrahydro-indolizin-3-yl)-methanol
Show/Hide
|
C15H26N2O
|
2
|
| 1 |
Ki = 416.87 nM
|
|
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| 2 |
Ki = 420 nM
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CP0430147
|
((S)-3-Methyl-5,6,7,8-tetrahydro-indolizin-7-yl)-dipropyl-amine
Show/Hide
|
C15H26N2
|
2
|
| 1 |
Ki = 416.87 nM
|
|
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| 2 |
Ki = 430 nM
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CP0373604
|
1-(2,5-Dimethylphenyl)-4-[4-(2,5-dimethylphenyl)piperazin-1-yl]butan-1-one
Show/Hide
|
C25H33NO
|
1
|
| 1 |
Ki = 420 nM
|
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|
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CP0389230
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8-hydroxy-5-(4-propylpiperazin-1-yl)-1H-quinolin-2-one
Show/Hide
|
C16H21N3O2
|
1
|
| 1 |
Ki = 420 nM
|
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CP0377047
|
7-[4-(4-Methoxy-phenyl)-piperidin-1-ylmethyl]-4H-benzo[1,4]oxazin-3-one
Show/Hide
|
C21H24N2O3
|
1
|
| 1 |
Ki = 428 nM
|
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CP0481585
|
[1-(4-oxo-4-phenylbutyl)-4-phenylpiperidin-4-yl] propanoate
Show/Hide
|
C24H29NO3
|
1
|
| 1 |
Ki = 429 nM
|
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|
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CP0460885
|
1-(4-Chloro-benzyl)-4-[5-(4-chloro-phenyl)-isoxazol-3-yl]-piperidine
Show/Hide
|
C21H20Cl2N2O
|
1
|
| 1 |
Ki = 430 nM
|
|
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CP0473629
|
1-[[4-[[1-(2-ethoxyethyl)triazol-4-yl]methoxy]-3-methoxyphenyl]methyl]-4-(2-methoxyphenyl)piperazine
Show/Hide
|
C26H35N5O4
|
1
|
| 1 |
Ki = 440 nM
|
|
|
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CP0382362
|
3-(8,11-dimethylbenzo[c]phenothiazin-7-yl)-N,N-dimethylpropan-1-amine
Show/Hide
|
C23H26N2S
|
1
|
| 1 |
Ki = 442 nM
|
|
|
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CP0413872
|
1-(2-methoxyphenyl)-4-[[3-[(4-methylpiperazin-1-yl)methyl]azulen-1-yl]methyl]piperazine
Show/Hide
|
C28H36N4O
|
1
|
| 1 |
Ki = 460 nM
|
|
|
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CP0495422
|
1-(4-Fluoro-phenyl)-3-(1,2,4,4a,5,6-hexahydro-pyrazino[1,2-a]quinolin-3-yl)-propan-1-one
Show/Hide
|
C21H23FN2O
|
1
|
| 1 |
Ki = 465 nM
|
|
|
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CP0408564
|
8-iodo-2-[4-(2-methoxyphenyl)piperazin-1-ylmethyl]-6-methylimidazo[1,2-a]pyridine
Show/Hide
|
C20H23IN4O
|
1
|
| 1 |
Ki = 470 nM
|
|
|
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CP0372350
|
11-methoxy-7-methyl-6,7,8,9,14,15-hexahydro-5H-indolo[3,2-f][3]benzazecine
Show/Hide
|
C21H24N2O
|
1
|
| 1 |
Ki = 475 nM
|
|
|
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CP0081150
|
4-[3-(4-Chloro-phenyl)-4-methyl-isoxazol-5-yl]-1-phenethyl-piperidine
Show/Hide
|
C23H25ClN2O
|
1
|
| 1 |
Ki = 480 nM
|
|
|
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CP0299385
|
7-{[4-(3,4-Dichlorophenyl)piperazin-1-yl]methyl}-3-methyl-2-pyrrolidin-1-yl-3,5-dihydro-4H-pyrrolo[3,2-d]pyrimidin-4-one
Show/Hide
|
C22H26Cl2N6O
|
1
|
| 1 |
Ki = 480 nM
|
|
|
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CP0445341
|
N-[4-(2,5-diazatetracyclo[13.4.0.02,7.08,13]nonadeca-1(19),8,10,12,15,17-hexaen-5-yl)butyl]thiophene-2-carboxamide
Show/Hide
|
C26H29N3OS
|
1
|
| 1 |
Ki = 500 nM
|
|
|
|
CP0454988
|
2-[4-(2,5-diazatetracyclo[13.4.0.02,7.08,13]nonadeca-1(19),8,10,12,15,17-hexaen-5-yl)butyl]isoindole-1,3-dione
Show/Hide
|
C29H29N3O2
|
1
|
| 1 |
Ki = 500 nM
|
|
|
|
CP0463577
|
bis[4-(4-chlorophenyl)-1-[4-(4-fluorophenyl)-4-oxobutyl]piperidin-4-yl] docosanedioate
Show/Hide
|
C64H84Cl2F2N2O6
|
1
|
| 1 |
Ki = 500 nM
|
|
|
|
CP0458824
|
N-[4-[2-[(6R)-6-(dipropylamino)-1-methoxy-5,6,7,8-tetrahydronaphthalen-2-yl]ethyl]phenyl]methanesulfonamide
Show/Hide
|
C26H38N2O3S
|
1
|
| 1 |
Ki = 501.19 nM
|
|
|
|
CP0448271
|
(2R,7R)-6-propyl-3,9,15-trioxa-6-azatetracyclo[8.7.0.02,7.012,16]heptadeca-1(10),11,16-triene
Show/Hide
|
C16H21NO3
|
1
|
| 1 |
Ki = 501.19 nM
|
|
|
|
CP0412146
|
3,5-dichloro-N-[2-[4-(2,3-dichlorophenyl)piperazin-1-yl]ethyl]-2-hydroxy-6-methoxybenzamide
Show/Hide
|
C20H21Cl4N3O3
|
1
|
| 1 |
Ki = 501.19 nM
|
|
|
|
CP0674190
|
5-Chloro-3-methyl-benzo[b]thiophene-2-sulfonic acid (4-methoxy-3-piperazin-1-yl-phenyl)-amide hydrochloride
Show/Hide
|
C20H23Cl2N3O3S2
|
1
|
| 1 |
Ki = 501.19 nM
|
|
|
|
CP0041243
|
5-chloro-N-[4-methoxy-3-(piperazin-1-yl)phenyl]-3-methyl-1-benzothiophene-2-sulfonamide hydrochloride
Show/Hide
|
C20H22ClN3O3S2
|
1
|
| 1 |
Ki = 501.19 nM
|
|
|
|
CP0296883
|
7-fluoro-6-[[1-[2-(7-fluoro-2-methylquinolin-5-yl)oxyethyl]piperidin-4-yl]methyl]-4H-1,4-benzoxazin-3-one
Show/Hide
|
C26H27F2N3O3
|
1
|
| 1 |
Ki = 501.19 nM
|
|
|
|
CP0404789
|
(R)-7-Dipropylamino-5,6,7,8-tetrahydro-indolizine-1-carbaldehyde
Show/Hide
|
C15H24N2O
|
2
|
| 1 |
Ki = 501.19 nM
|
|
|
| 2 |
Ki = 510 nM
|
|
|
|
CP0266803
|
1-[(2-chlorophenyl)methyl]-3-[2-(1,3-dihydroisoindol-2-yl)ethyl]imidazolidin-2-one
Show/Hide
|
C20H22ClN3O
|
1
|
| 1 |
Ki = 501.19 nM
|
|
|
|
CP0266804
|
1-[2-(1,3-dihydroisoindol-2-yl)ethyl]-3-[1-[3-(trifluoromethyl)phenyl]ethyl]imidazolidin-2-one
Show/Hide
|
C22H24F3N3O
|
1
|
| 1 |
Ki = 501.19 nM
|
|
|
|
CP0357993
|
1-(1-acetylindol-5-yl)-3-[2-(1,3-dihydroisoindol-2-yl)ethyl]imidazolidin-2-one
Show/Hide
|
C23H24N4O2
|
1
|
| 1 |
Ki = 501.19 nM
|
|
|
|
CP0422140
|
1-methyl-2-((4-(2-(trifluoromethyl)phenyl)piperidin-1-yl)methyl)-1H-benzo[d]imidazole
Show/Hide
|
C21H22F3N3
|
1
|
| 1 |
Ki = 501.19 nM
|
|
|
|
CP0398688
|
N-[4-[2-[[3-(benzenesulfonyl)-6,7-dihydrocyclobuta[e]indol-7-yl]methyl-methylamino]ethyl]phenyl]acetamide
Show/Hide
|
C28H29N3O3S
|
1
|
| 1 |
Ki = 501.19 nM
|
|
|
|
CP0058675
|
N-methyl-3-(1-tetracyclo[6.6.2.02,7.09,14]hexadeca-2,4,6,9,11,13-hexaenyl)propan-1-amine
Show/Hide
|
C20H23N
|
1
|
| 1 |
Ki = 504 nM
|
|
|
|
CP0202373
|
3-methoxy-7-methyl-6,7,8,9,10,15-hexahydro-5H-dibenzo[d,g]azacycloundecene
Show/Hide
|
C20H25NO
|
1
|
| 1 |
Ki = 507 nM
|
|
|
|
CP0408428
|
8-(1,4-diazepan-1-yl)-5-hydroxy-4H-1,4-benzoxazin-3-one
Show/Hide
|
C13H17N3O3
|
1
|
| 1 |
Ki = 510 nM
|
|
|
|
CP0061808
|
1-Phenyl-4-(4-phenyl-1H-pyrrol-2-ylmethyl)-piperazine
Show/Hide
|
C21H23N3
|
2
|
| 1 |
Ki = 514 nM
|
|
|
| 2 |
Ki = 540 nM
|
|
|
|
CP0371883
|
3-(4-(4-(2-methoxyphenyl)-1-piperazinyl)butyl)quinazolin-4(3H)-one
Show/Hide
|
C22H26N4O
|
1
|
| 1 |
Ki = 527 nM
|
|
|
|
CP0421398
|
3-{2-[4-(4-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-1H-pyrrolo[2,3-b]pyridine
Show/Hide
|
C20H24N4O
|
1
|
| 1 |
Ki = 530 nM
|
|
|
|
CP0381528
|
3-[[4-(2-methoxyphenyl)piperazin-1-yl]methyl]azulene-1-carbonitrile
Show/Hide
|
C23H23N3O
|
1
|
| 1 |
Ki = 530 nM
|
|
|
|
CP0178944
|
1-(4-Fluorophenyl)-4-[(1-phenyl-1H-pyrazol-4-yl)methyl]piperazine
Show/Hide
|
C20H21FN4
|
2
|
| 1 |
Ki = 537.03 nM
|
|
|
| 2 |
Ki = 540 nM
|
|
|
|
CP0410598
|
3-[4-(2-Chloro-phenyl)-piperazin-1-ylmethyl]-1H-indole-5-carbonitrile
Show/Hide
|
C20H19ClN4
|
1
|
| 1 |
Ki = 550 nM
|
|
|
|
CP0404187
|
2-(1-Benzyl-1,2,3,6-tetrahydro-pyridin-4-yl)-benzothiazole
Show/Hide
|
C19H18N2S
|
1
|
| 1 |
Ki = 560 nM
|
|
|
|
CP0391281
|
(7R)-N,N-dipropyl-5,6,7,8-tetrahydroindolizin-7-amine
Show/Hide
|
C14H24N2
|
2
|
| 1 |
Ki = 560 nM
|
|
|
| 2 |
Ki = 1659.59 nM
|
|
|
|
CP0916147
|
2-{3-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-propyl}-isoindole-1,3-dione oxalic acid
Show/Hide
|
C24H27N3O7
|
1
|
| 1 |
Ki = 560 nM
|
|
|
|
CP0183661
|
1-Phenyl-4-(1H-pyrrol-2-ylmethyl)-piperazine
Show/Hide
|
C15H19N3
|
1
|
| 1 |
Ki = 570 nM
|
|
|
|
CP0522877
|
(7S)-N,N-dipropyl-5,6,7,8-tetrahydroindolizin-7-amine
Show/Hide
|
C14H24N2
|
1
|
| 1 |
Ki = 575.44 nM
|
|
|
|
CP0401018
|
(1-Benzyl-piperidin-4-yl)-[2-(5-bromo-2-methoxy-phenyl)-oxazol-4-ylmethyl]-amine
Show/Hide
|
C23H26BrN3O2
|
1
|
| 1 |
Ki = 580 nM
|
|
|
|
CP0419187
|
[3-[[4-(2-methoxyphenyl)piperazin-1-yl]methyl]azulen-1-yl]methanol
Show/Hide
|
C23H26N2O2
|
1
|
| 1 |
Ki = 580 nM
|
|
|
|
CP0448005
|
((R)-3-Methyl-5,6,7,8-tetrahydro-indolizin-7-yl)-dipropyl-amine
Show/Hide
|
C15H26N2
|
2
|
| 1 |
Ki = 590 nM
|
|
|
| 2 |
Ki = 616.6 nM
|
|
|
|
CP0457600
|
3-[[4-(6-fluoropyridin-2-yl)piperazin-1-yl]methyl]pyrazolo[1,5-a]pyridine
Show/Hide
|
C17H18FN5
|
1
|
| 1 |
Ki = 590 nM
|
|
|
|
CP0333143
|
3-(2-{4-[1-(4-Fluoro-phenyl)-5-(1-methyl-1H-[1,2,4]triazol-3-yl)-1H-indol-3-yl]-piperidin-1-yl}-ethyl)-1H-quinazoline-2,4-dione
Show/Hide
|
C32H30FN7O2
|
1
|
| 1 |
Ki = 590 nM
|
|
|
|
CP0374762
|
1-[[4-[4-(1-butyltriazol-4-yl)butoxy]-3-methoxyphenyl]methyl]-4-(2-methoxyphenyl)piperazine
Show/Hide
|
C29H41N5O3
|
1
|
| 1 |
Ki = 590 nM
|
|
|
|
CP0188439
|
4-(4-Benzyl-piperazin-1-yl)-5-chloro-1,3-dihydro-indol-2-one
Show/Hide
|
C19H20ClN3O
|
1
|
| 1 |
Ki = 591.3 nM
|
|
|
|
CP0395310
|
6-iodo-2-[4-(2-methoxyphenyl)piperazin-1-ylmethyl]imidazo[1,2-a]pyridine
Show/Hide
|
C19H21IN4O
|
1
|
| 1 |
Ki = 600 nM
|
|
|
|
CP0415581
|
4-bromo-N-[2-[4-(1H-indol-2-ylmethyl)piperazin-1-yl]ethyl]-N-propylaniline
Show/Hide
|
C24H31BrN4
|
1
|
| 1 |
Ki = 600 nM
|
|
|
|
CP0857261
|
1-(4-(3-((2-Aminoethyl)disulfanyl)propoxy)-3-methoxyphenethyl)-4-(4-chlorophenyl)piperidin-4-ol ditrifluoroacetic acid
Show/Hide
|
C29H37ClF6N2O7S2
|
1
|
| 1 |
Ki = 600 nM
|
|
|
|
CP0374761
|
1-[[4-[3-(1-butyltriazol-4-yl)propoxy]-3-methoxyphenyl]methyl]-4-(2-methoxyphenyl)piperazine
Show/Hide
|
C28H39N5O3
|
1
|
| 1 |
Ki = 610 nM
|
|
|
|
CP0399134
|
4-[(1S)-1-hydroxy-2-[2-(2-methoxyphenoxy)ethylamino]ethyl]benzene-1,2-diol
Show/Hide
|
C17H21NO5
|
1
|
| 1 |
Ki = 610 nM
|
|
|
|
CP0406481
|
N-[2-[4-[2-(1H-indol-3-yl)ethyl]piperazin-1-yl]ethyl]-4-methoxyaniline
Show/Hide
|
C23H30N4O
|
1
|
| 1 |
Ki = 620 nM
|
|
|
|
CP0436906
|
2-[1-(3-Chloro-benzyl)-1,2,3,6-tetrahydro-pyridin-4-yl]-benzothiazole
Show/Hide
|
C19H17ClN2S
|
1
|
| 1 |
Ki = 630 nM
|
|
|
|
CP0299386
|
7-{[4-(4-Fluorophenyl)piperazin-1-yl]methyl}-3-methyl-2-pyrrolidin-1-yl-3,5-dihydro-4H-pyrrolo[3,2-d]pyrimidin-4-one
Show/Hide
|
C22H27FN6O
|
1
|
| 1 |
Ki = 630 nM
|
|
|
|
CP0401623
|
4-[2-[6-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-2-yl]ethyl]benzamide
Show/Hide
|
C25H34N2O
|
1
|
| 1 |
Ki = 630.96 nM
|
|
|
|
CP0389417
|
N-[4-[(4aR,10bR)-7-hydroxy-2,3,4a,5,6,10b-hexahydro-1H-benzo[f]quinolin-4-yl]butyl]-4-phenylbenzamide
Show/Hide
|
C30H34N2O2
|
1
|
| 1 |
Ki = 630.96 nM
|
|
|
|
CP0051242
|
(R)-1-(2-(1-(3-bromo-benzenesulfonyl)-pyrrolidin-2-yl)-ethyl)-4-methyl piperidine
Show/Hide
|
C18H27BrN2O2S
|
1
|
| 1 |
Ki = 630.96 nM
|
|
|
|
CP0165719
|
N-[3-[(8aR)-3,4,6,7,8,8a-hexahydro-1H-pyrrolo[1,2-a]pyrazin-2-yl]-4-methoxyphenyl]-5-chloro-3-methyl-1-benzothiophene-2-sulfonamide
Show/Hide
|
C23H26ClN3O3S2
|
1
|
| 1 |
Ki = 630.96 nM
|
|
|
|
CP0152118
|
6-[[1-[2-(2-methylquinolin-5-yl)oxyethyl]piperidin-4-yl]methyl]-4H-1,4-benzoxazin-3-one
Show/Hide
|
C26H29N3O3
|
1
|
| 1 |
Ki = 630.96 nM
|
|
|
|
CP0861232
|
3-Cyclopentyl-N-(2-dimethylamino-ethyl)-N-[4'-(phenethylamino-methyl)-biphenyl-4-ylmethyl]-propionamide with di TFA
Show/Hide
|
C38H47F6N3O5
|
1
|
| 1 |
Ki = 630.96 nM
|
|
|
|
CP0102833
|
1-benzyl-3-[2-(1,3-dihydroisoindol-2-yl)ethyl]imidazolidin-2-one
Show/Hide
|
C20H23N3O
|
1
|
| 1 |
Ki = 630.96 nM
|
|
|
|
CP0148906
|
1-(3-chlorophenyl)-3-[2-[3-(3-methoxyphenyl)piperidin-1-yl]ethyl]imidazolidin-2-one
Show/Hide
|
C23H28ClN3O2
|
1
|
| 1 |
Ki = 630.96 nM
|
|
|
|
CP0466960
|
2-[(4S,5S)-9-(benzenesulfonyl)-5-(dimethylamino)-9-azatricyclo[6.3.0.03,6]undeca-1,3(6),7,10-tetraen-4-yl]ethanol
Show/Hide
|
C20H22N2O3S
|
1
|
| 1 |
Ki = 630.96 nM
|
|
|
|
CP0430103
|
1-Benzyl-4-[2-(5-bromo-2-methoxy-phenyl)-thiazol-4-ylmethyl]-piperazine
Show/Hide
|
C22H24BrN3OS
|
1
|
| 1 |
Ki = 640 nM
|
|
|
|
CP0343244
|
2,5,7-Trimethyl-3-[4-(2-pyridin-2-ylpiperazin-1-yl)methyl]imidazo[1,2-c]pyrimidine
Show/Hide
|
C19H24N6
|
1
|
| 1 |
Ki = 640 nM
|
|
|
|
CP0477090
|
1-[N-[(4-cyanophenyl)methyl]-4-fluoroanilino]-3-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]urea
Show/Hide
|
C29H33FN6O2
|
1
|
| 1 |
Ki = 640 nM
|
|
|
|
CP0089965
|
N-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]pyrazolo[1,5-a]pyridine-2-carboxamide
Show/Hide
|
C22H27N5O2
|
1
|
| 1 |
Ki = 645.65 nM
|
|
|
|
CP0430499
|
5-Chloro-2-[1-(4-chloro-benzyl)-1,2,3,6-tetrahydro-pyridin-4-yl]-benzothiazole
Show/Hide
|
C19H16Cl2N2S
|
1
|
| 1 |
Ki = 660 nM
|
|
|
|
CP0402209
|
1-[2-(5-Bromo-2-methoxy-phenyl)-oxazol-4-ylmethyl]-4-phenyl-piperazine
Show/Hide
|
C21H22BrN3O2
|
1
|
| 1 |
Ki = 660 nM
|
|
|
|
CP0378343
|
2-(4-(4-(4-chlorophenyl)-1-piperazinyl)butyl)-1-isoindolinone
Show/Hide
|
C22H26ClN3O
|
1
|
| 1 |
Ki = 660 nM
|
|
|
|
CP0399131
|
4-[(1S)-1-hydroxy-2-[2-[3-methoxy-4-(3-phenylpropoxy)phenyl]ethylamino]ethyl]benzene-1,2-diol
Show/Hide
|
C26H31NO5
|
1
|
| 1 |
Ki = 660 nM
|
|
|
|
CP0550960
|
1-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]-3-(4-methoxy-N-prop-2-enylanilino)urea
Show/Hide
|
C25H35N5O3
|
1
|
| 1 |
Ki = 660 nM
|
|
|
|
CP0082575
|
1-Phenyl-4-(4-phenylethynyl-1H-pyrrol-2-ylmethyl)-piperazine
Show/Hide
|
C23H23N3
|
1
|
| 1 |
Ki = 670 nM
|
|
|
|
CP0374898
|
8-bromo-2-[4-(2-methoxyphenyl)piperazin-1-ylmethyl]-6-methylimidazo[1,2-a]pyridine
Show/Hide
|
C20H23BrN4O
|
1
|
| 1 |
Ki = 670 nM
|
|
|
|
CP0495918
|
((S)-1-Methyl-5,6,7,8-tetrahydro-indolizin-7-yl)-dipropyl-amine
Show/Hide
|
C15H26N2
|
2
|
| 1 |
Ki = 676.08 nM
|
|
|
| 2 |
Ki = 750 nM
|
|
|
|
CP0052140
|
7-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-4H-benzo[1,4]oxazin-3-one
Show/Hide
|
C19H20ClN3O2
|
1
|
| 1 |
Ki = 679 nM
|
|
|
|
CP0105167
|
3-{4-[1-(4-Fluoro-phenyl)-5-pyrimidin-2-yl-1H-indol-3-yl]-piperidin-1-yl}-propionitrile
Show/Hide
|
C26H24FN5
|
1
|
| 1 |
Ki = 680 nM
|
|
|
|
CP0401112
|
5-hydroxy-8-[(1R)-1-hydroxy-2-[2-[3-methoxy-4-(3-phenylpropoxy)phenyl]ethylamino]ethyl]-4H-1,4-benzoxazin-3-one
Show/Hide
|
C28H32N2O6
|
1
|
| 1 |
Ki = 690 nM
|
|
|
|
CP0853882
|
1-(2-(4-(4-Chlorophenyl)-4-hydroxypiperidin-1-yl)ethyl)-3-(2-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)ethyl)urea
Show/Hide
|
C22H26ClF3N4O6
|
1
|
| 1 |
Ki = 690 nM
|
|
|
|
CP0919206
|
1-(2-methoxyphenyl)-4-{5-[4-(2-methoxyphenyl)hexahydro-1-pyrazinyl]perhydro-2-pentalenyl}hexahydropyrazine oxalic acid
Show/Hide
|
C32H44N4O6
|
1
|
| 1 |
Ki = 700 nM
|
|
|
|
CP0438118
|
1-(N-benzyl-4-fluoroanilino)-3-[2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl]urea
Show/Hide
|
C27H32FN5O2
|
1
|
| 1 |
Ki = 700 nM
|
|
|
|
CP0079074
|
4-[(4-phenylpiperazin-1-yl)methyl]-1H-pyrrole-2-carbonitrile
Show/Hide
|
C16H18N4
|
1
|
| 1 |
Ki = 720 nM
|
|
|
|
CP0373655
|
((R)-7-Dipropylamino-5,6,7,8-tetrahydro-indolizin-3-yl)-methanol
Show/Hide
|
C15H26N2O
|
2
|
| 1 |
Ki = 724.44 nM
|
|
|
| 2 |
Ki = 7400 nM
|
|
|
|
CP0849214
|
Naphthalene-2-carboxylic acid 2-[4-(2-methoxy-phenyl)-piperazin-1-ylmethyl]-benzylamide oxalic acid
Show/Hide
|
C32H33N3O6
|
1
|
| 1 |
Ki = 750 nM
|
|
|
|
CP0099174
|
4-[5-(4-Chloro-phenyl)-4-methyl-isoxazol-3-yl]-1-phenethyl-piperidine
Show/Hide
|
C23H25ClN2O
|
1
|
| 1 |
Ki = 770 nM
|
|
|
|
CP0392597
|
1-Benzyl-4-(2-oxazol-5-yl-pyrrol-1-yl)-piperidine
Show/Hide
|
C19H21N3O
|
1
|
| 1 |
Ki = 770 nM
|
|
|
|
CP0415031
|
((S)-2-Methyl-5,6,7,8-tetrahydro-indolizin-7-yl)-dipropyl-amine
Show/Hide
|
C15H26N2
|
2
|
| 1 |
Ki = 770 nM
|
|
|
| 2 |
Ki = 794.33 nM
|
|
|
|
CP0286302
|
7-methyl-6,7,8,9,10,15-hexahydro-5H-dibenzo[d,g]azacycloundecene-2-ol
Show/Hide
|
C19H23NO
|
1
|
| 1 |
Ki = 776 nM
|
|
|
|
CP0399906
|
N-[5-[(5-chloro-6-oxo-4-piperazin-1-ylpyridazin-1-yl)methyl]-2-methylphenyl]-4-phenylbenzamide
Show/Hide
|
C29H28ClN5O2
|
1
|
| 1 |
Ki = 776.25 nM
|
|
|
|
CP0399136
|
8-hydroxy-5-[(1S)-1-hydroxy-2-[2-[3-methoxy-4-(3-phenylpropoxy)phenyl]ethylamino]ethyl]-1H-quinolin-2-one
Show/Hide
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C29H32N2O5
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1
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| 1 |
Ki = 790 nM
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CP0408429
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8-(4-methylpiperazin-1-yl)-2,3-dihydro-1,4-benzodioxin-5-ol
Show/Hide
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C13H18N2O3
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1
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| 1 |
Ki = 790 nM
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CP0453723
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N-[4-[(4aR,10bR)-7-methoxy-2,3,4a,5,6,10b-hexahydro-1H-benzo[f]quinolin-4-yl]butyl]-4-phenylbenzamide
Show/Hide
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C31H36N2O2
|
1
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| 1 |
Ki = 794.33 nM
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CP0185590
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4-Bromo-N-[4-methoxy-3-(4-methyl-piperazin-1-yl)-phenyl]-benzenesulfonamide
Show/Hide
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C18H22BrN3O3S
|
1
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| 1 |
Ki = 794.33 nM
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CP0035199
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5-fluoro-6-[[1-[2-(7-fluoro-2-methylquinolin-5-yl)oxyethyl]piperidin-4-yl]methyl]-4H-1,4-benzoxazin-3-one
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C26H27F2N3O3
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1
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| 1 |
Ki = 794.33 nM
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CP0405374
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4-[[5-(5-ethylsulfonyl-2-methoxyphenyl)-1H-pyrrol-2-yl]methyl]morpholine
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C18H24N2O4S
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1
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| 1 |
Ki = 794.33 nM
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CP0398689
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N-methyl-1-(9-naphthalen-1-ylsulfonyl-9-azatricyclo[6.3.0.03,6]undeca-1,3(6),7,10-tetraen-5-yl)methanamine
Show/Hide
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C22H20N2O2S
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1
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| 1 |
Ki = 794.33 nM
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CP0355375
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6-bromo-2-[4-(2-methoxyphenyl)piperazin-1-ylmethyl]imidazo[1,2-a]pyridine
Show/Hide
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C19H21BrN4O
|
1
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| 1 |
Ki = 800 nM
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CP0489169
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1-[[1-(6-fluorohexyl)triazol-4-yl]methyl]-4-(2-methoxyphenyl)piperazine
Show/Hide
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C20H30FN5O
|
1
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| 1 |
Ki = 800 nM
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CP0388359
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N-[3-[(5-chloro-6-oxo-4-piperazin-1-ylpyridazin-1-yl)methyl]phenyl]-4-phenylbenzamide
Show/Hide
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C28H26ClN5O2
|
1
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| 1 |
Ki = 812.83 nM
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CP0183485
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1-(4-Chloro-benzyl)-4-[5-(4-chloro-phenyl)-1H-pyrazol-3-yl]-piperidine
Show/Hide
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C21H21Cl2N3
|
1
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| 1 |
Ki = 820 nM
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CP0409934
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6-(4-Phenyl-piperazin-1-ylmethyl)-4H-benzo[1,4]oxazin-3-one
Show/Hide
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C19H21N3O2
|
1
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| 1 |
Ki = 839 nM
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CP0381009
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3-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-7-phenyl-pyrazolo[1,5-a]pyridine
Show/Hide
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C24H23ClN4
|
1
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| 1 |
Ki = 840 nM
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CP0298304
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1-(4-Ethynyl-1H-pyrrol-2-ylmethyl)-4-phenyl-piperazine
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C17H19N3
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1
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| 1 |
Ki = 850 nM
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CP0499699
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2-[4-(3,4-dichlorophenyl)piperazin-1-ylmethyl]-6-(piperidin-1-yl)imidazo[1,2-b]pyridazine
Show/Hide
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C22H26Cl2N6
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1
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| 1 |
Ki = 850 nM
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CP0536409
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1-[3-[4-(4-chlorophenyl)piperazin-1-yl]propyl]-3-[N-[(4-fluorophenyl)methyl]anilino]urea
Show/Hide
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C27H31ClFN5O
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1
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| 1 |
Ki = 850 nM
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CP0508435
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7-[4-(3,4-Dimethyl-phenyl)-piperidin-1-ylmethyl]-4H-benzo[1,4]oxazin-3-one
Show/Hide
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C22H26N2O2
|
1
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| 1 |
Ki = 859 nM
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CP0482775
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1-[4-methoxy-N-(2-methylprop-2-enyl)anilino]-3-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]urea
Show/Hide
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C26H37N5O3
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1
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| 1 |
Ki = 860 nM
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CP0404326
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6-[4-(3,4-Dimethyl-phenyl)-piperazin-1-ylmethyl]-4H-benzo[1,4]oxazin-3-one
Show/Hide
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C21H25N3O2
|
1
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| 1 |
Ki = 864 nM
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CP0407200
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3-[4-(3,4-Dichloro-phenyl)-piperazin-1-ylmethyl]-1H-indole-5-carbonitrile
Show/Hide
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C20H18Cl2N4
|
1
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| 1 |
Ki = 870 nM
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CP0460411
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4-(4-Benzyl-piperazin-1-yl)-1H-benzoimidazole
Show/Hide
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C18H20N4
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1
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| 1 |
Ki = 870.5 nM
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CP0449378
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2-[4-(3,4-dichlorophenyl)piperazin-1-ylmethyl]-6-(4-methylpiperazin-1-yl)imidazo[1,2-b]pyridazine
Show/Hide
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C22H27Cl2N7
|
1
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| 1 |
Ki = 880 nM
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CP0514672
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(4aS,11bS)-4-propyl-2,3,4a,5,6,8,9,11b-octahydroisoindolo[5,6-h][1,4]benzoxazin-10-one
Show/Hide
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C17H22N2O2
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1
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| 1 |
Ki = 891.25 nM
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CP0454722
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5-Chloro-2-[1-(4-chloro-benzyl)-1,2,3,6-tetrahydro-pyridin-4-yl]-1H-benzoimidazole
Show/Hide
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C19H17Cl2N3
|
1
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| 1 |
Ki = 900 nM
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CP0430146
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((R)-2-Methyl-5,6,7,8-tetrahydro-indolizin-7-yl)-dipropyl-amine
Show/Hide
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C15H26N2
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2
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| 1 |
Ki = 912.01 nM
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| 2 |
Ki = 1300 nM
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CP0373264
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2-[4-(2-Chloro-phenyl)-piperazin-1-ylmethyl]-1H-indole-6-carbonitrile
Show/Hide
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C20H19ClN4
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1
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| 1 |
Ki = 920 nM
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CP0477865
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2-[[4-(6-bromopyridin-2-yl)piperazin-1-yl]methyl]pyrazolo[1,5-a]pyridine
Show/Hide
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C17H18BrN5
|
1
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| 1 |
Ki = 930 nM
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CP0428513
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N-[4-[4-[4-(2-ethoxyethoxymethyl)-2-methoxyphenyl]piperazin-1-yl]butyl]benzamide
Show/Hide
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C27H39N3O4
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1
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| 1 |
Ki = 930 nM
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CP0401023
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N-[(4-bromophenyl)methyl]-N-[2-[4-(1H-indol-2-ylmethyl)piperazin-1-yl]ethyl]propan-1-amine
Show/Hide
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C25H33BrN4
|
1
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| 1 |
Ki = 930 nM
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CP0428040
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2-[[4-[2-(2-fluoroethoxy)phenyl]piperazin-1-yl]methyl]pyrazolo[1,5-a]pyridine
Show/Hide
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C20H23FN4O
|
1
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| 1 |
Ki = 940 nM
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CP0298952
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7-methyl-6,7,8,9,14,15-hexahydro-5H-indolo[3,2-f][3]benzazecin-11-ol
Show/Hide
|
C20H22N2O
|
1
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| 1 |
Ki = 944 nM
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CP0398439
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N-[4-(dipropylamino)butyl]-4-phenylbenzamide
Show/Hide
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C23H32N2O
|
1
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| 1 |
Ki = 950 nM
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CP0299382
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2-(dimethylamino)-6-((4-(2-methoxyphenyl)piperazin-1-yl)methyl)-3H-pyrrolo[2,3-d]pyrimidin-4(7H)-one
Show/Hide
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C20H26N6O2
|
1
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| 1 |
Ki = 960 nM
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CP0461112
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3,5-dichloro-2-hydroxy-6-methoxy-N-[2-(4-phenylpiperazin-1-yl)ethyl]benzamide
Show/Hide
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C20H23Cl2N3O3
|
1
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| 1 |
Ki = 1000 nM
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CP0271460
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(R)-1-(2-(1-(3,4-Dichloro-benzene sulfonyl)-pyrrolidin-2-yl)-ethyl)-4-methyl piperidine
Show/Hide
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C18H26Cl2N2O2S
|
1
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| 1 |
Ki = 1000 nM
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CP0712961
|
(R)-sulfonamide1-(4-methylhexahydro-1-pyridinyl)-2-[1-(1-naphthylsulfonyl)hexahydro-2-pyridinyl]ethane
Show/Hide
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C23H32N2O2S
|
1
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| 1 |
Ki = 1000 nM
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CP0216543
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N-[3-(1,3,4,6,7,8,9,9a-octahydropyrido[1,2-a]pyrazin-2-yl)-4-methoxyphenyl]-5-chloro-3-methyl-1-benzothiophene-2-sulfonamide
Show/Hide
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C24H28ClN3O3S2
|
1
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| 1 |
Ki = 1000 nM
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CP0384627
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1-Methoxy-4-phenylethynyl-naphthalene-2-carboxylic acid ((R)-1-benzyl-pyrrolidin-3-yl)-amide
Show/Hide
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C31H28N2O2
|
1
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| 1 |
Ki = 1000 nM
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CP0449377
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6-bromo-2-[4-(3,4-dichlorophenyl)piperazin-1-ylmethyl]imidazo[1,2-a]pyridine
Show/Hide
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C18H17BrCl2N4
|
1
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| 1 |
Ki = 1000 nM
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CP0451866
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2-[4-(2-methoxyphenyl)piperazin-1-ylmethyl]-5-(pyrazol-1-yl)imidazo[1,2-a]pyridine
Show/Hide
|
C22H24N6O
|
1
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| 1 |
Ki = 1000 nM
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CP0295528
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6-[[1-[2-(7-chloro-2-methylquinolin-5-yl)oxyethyl]piperidin-4-yl]methyl]-5-fluoro-4H-1,4-benzoxazin-3-one
Show/Hide
|
C26H27ClFN3O3
|
1
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| 1 |
Ki = 1000 nM
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CP0853819
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(E)-N-(2-Dimethylamino-ethyl)-N-[4'-(phenethylamino-methyl)-biphenyl-4-ylmethyl]-3-phenyl-acrylamide TFA
Show/Hide
|
C37H40F3N3O3
|
1
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| 1 |
Ki = 1000 nM
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CP0428819
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Benzoic acid 4-isoquinolin-1-yl-1-phenethyl-piperidin-4-yl ester
Show/Hide
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C29H28N2O2
|
1
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| 1 |
Ki = 1000 nM
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CP0453314
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3,5-Bis-[1-(4-bromo-phenyl)-meth-(E)-ylidene]-1-butyl-piperidin-4-one
Show/Hide
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C23H23Br2NO
|
1
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| 1 |
Ki = 1000 nM
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CP0451468
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(10S,16R)-5-(benzenesulfonyl)-5,13-diazatetracyclo[7.7.0.02,6.010,16]hexadeca-1(9),2(6),3,7-tetraene
Show/Hide
|
C20H20N2O2S
|
1
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| 1 |
Ki = 1000 nM
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CP0471145
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2-[(4S,5S)-9-(benzenesulfonyl)-5-(methylamino)-9-azatricyclo[6.3.0.03,6]undeca-1,3(6),7,10-tetraen-4-yl]ethanol
Show/Hide
|
C19H20N2O3S
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1
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| 1 |
Ki = 1000 nM
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CP0422207
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1-Benzyl-4-[2-(5-bromo-2-methoxy-phenyl)-oxazol-4-ylmethyl]-piperazine
Show/Hide
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C22H24BrN3O2
|
1
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| 1 |
Ki = 1050 nM
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CP0412041
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2-(1H-Pyrrolo[2,3-b]pyridin-2-ylmethyl)-1,2,3,4-tetrahydro-isoquinoline
Show/Hide
|
C17H17N3
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1
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| 1 |
Ki = 1100 nM
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CP0477094
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1-(N-benzylanilino)-3-[3-[4-(4-chlorophenyl)piperazin-1-yl]propyl]urea
Show/Hide
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C27H32ClN5O
|
1
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| 1 |
Ki = 1100 nM
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CP0426968
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3-methoxy-7-methyl-6,7,8,9,14,15-hexahydro-5H-indolo[3,2-f][3]benzazecine
Show/Hide
|
C21H24N2O
|
1
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| 1 |
Ki = 1135 nM
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CP0378034
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N-[4-[4-(5-methoxy-1,2-benzoxazol-3-yl)piperazin-1-yl]butyl]-3-pyrimidin-2-ylbenzamide
Show/Hide
|
C27H30N6O3
|
1
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| 1 |
Ki = 1140 nM
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CP0463242
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1-[2-(5-Bromo-2-methoxy-phenyl)-thiazol-4-ylmethyl]-4-phenyl-piperazine
Show/Hide
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C21H22BrN3OS
|
1
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| 1 |
Ki = 1190 nM
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CP0372647
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4-[5-(4-Chloro-phenyl)-4-methyl-1H-pyrazol-3-yl]-1-phenethyl-piperidine
Show/Hide
|
C23H26ClN3
|
1
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| 1 |
Ki = 1200 nM
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CP0414816
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((S)-1-Benzyl-pyrrolidin-3-ylmethyl)-[2-(5-bromo-2-methoxy-phenyl)-oxazol-4-ylmethyl]-methyl-amine
Show/Hide
|
C24H28BrN3O2
|
1
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| 1 |
Ki = 1200 nM
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CP0163622
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3-{4-[1-(4-Fluoro-phenyl)-5-(1-methyl-1H-[1,2,4]triazol-3-yl)-1H-indol-3-yl]-piperidin-1-yl}-propionitrile
Show/Hide
|
C25H25FN6
|
1
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| 1 |
Ki = 1200 nM
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CP0228798
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1-(2-{4-[1-(4-Fluoro-phenyl)-5-(2-methyl-2H-tetrazol-5-yl)-1H-indol-3-yl]-piperidin-1-yl}-ethyl)-imidazolidin-2-one
Show/Hide
|
C26H29FN8O
|
1
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| 1 |
Ki = 1200 nM
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CP0378751
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1-Phenyl-4-[(1-phenyl-1H-1,2,3-triazol-4-yl)methyl]piperazine
Show/Hide
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C19H21N5
|
1
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| 1 |
Ki = 1200 nM
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CP0427419
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2-((4-(2-methoxyphenyl)piperazin-1-yl)methyl)H-pyrazolo[1,5-a]pyridine
Show/Hide
|
C19H22N4O
|
1
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| 1 |
Ki = 1200 nM
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CP0508544
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N,N-diethyl-3-[4-[1-[(E)-4-(2-methylbenzimidazol-1-yl)but-2-enyl]benzimidazol-2-yl]phenoxy]propan-1-amine
Show/Hide
|
C32H37N5O
|
1
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| 1 |
Ki = 1201 nM
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CP0371908
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1-(4-(4-(4-chlorophenyl)-1-piperazinyl)butyl)indolin-2-one
Show/Hide
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C22H26ClN3O
|
1
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| 1 |
Ki = 1204 nM
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CP0496525
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3-Dipropylamino-1-(1,2,3,4-tetrahydro-phenanthren-9-yl)-propan-1-ol
Show/Hide
|
C23H33NO
|
1
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| 1 |
Ki = 1258 nM
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CP0540129
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[(4aR,10bR)-4-[4-[(4-phenylbenzoyl)amino]butyl]-2,3,4a,5,6,10b-hexahydro-1H-benzo[f]quinolin-7-yl] methanesulfonate
Show/Hide
|
C31H36N2O4S
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1
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| 1 |
Ki = 1258.93 nM
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CP0182705
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(R)-4-Methyl-1-(2-(1-toluene-3-sulfonyl)-pyrrolidin-2-yl)-ethyl)-piperidine (Oxalate salt)
Show/Hide
|
C19H30N2O2S
|
1
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| 1 |
Ki = 1258.93 nM
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CP0198069
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(R)-4-Methyl-1-(2-(1-(naphthalene-1-sulfonyl)-pyrrolidin-2-yl)-ethyl)-piperidine(10)
Show/Hide
|
C22H30N2O2S
|
1
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| 1 |
Ki = 1258.93 nM
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CP0332841
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6-[[1-[2-(7-chloro-2-methylquinolin-5-yl)oxyethyl]piperidin-4-yl]methyl]-8-fluoro-4H-1,4-benzoxazin-3-one
Show/Hide
|
C26H27ClFN3O3
|
1
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| 1 |
Ki = 1258.93 nM
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CP0377493
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2-[(6S,7R)-3-(benzenesulfonyl)-7-(methylamino)-6,7-dihydrocyclobuta[e]indol-6-yl]ethanol
Show/Hide
|
C19H20N2O3S
|
1
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| 1 |
Ki = 1258.93 nM
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CP0408929
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2-[(4S,5R)-9-(benzenesulfonyl)-4-(dimethylamino)-9-azatricyclo[6.3.0.03,6]undeca-1,3(6),7,10-tetraen-5-yl]ethanol
Show/Hide
|
C20H22N2O3S
|
1
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| 1 |
Ki = 1258.93 nM
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CP0414871
|
1-[3-(benzenesulfonyl)-6,7-dihydrocyclobuta[e]indol-7-yl]-N-methylmethanamine
Show/Hide
|
C18H18N2O2S
|
1
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| 1 |
Ki = 1258.93 nM
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CP0447467
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2-[(4R,5R)-9-(benzenesulfonyl)-4-(methylamino)-9-azatricyclo[6.3.0.03,6]undeca-1,3(6),7,10-tetraen-5-yl]ethanol
Show/Hide
|
C19H20N2O3S
|
1
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| 1 |
Ki = 1258.93 nM
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CP0466957
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2-[(6R,7S)-3-(benzenesulfonyl)-6-(methylamino)-6,7-dihydrocyclobuta[e]indol-7-yl]ethanol
Show/Hide
|
C19H20N2O3S
|
1
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| 1 |
Ki = 1258.93 nM
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CP0521742
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N-[4-[4-(5-methoxy-1,2-benzoxazol-3-yl)piperazin-1-yl]butyl]-3-(5-methyl-1,2,4-oxadiazol-3-yl)benzamide
Show/Hide
|
C26H30N6O4
|
1
|
| 1 |
Ki = 1285 nM
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CP0483626
|
3-(4-Phenethyl-piperidin-1-ylmethyl)-1H-pyrrolo[2,3-b]pyridine
Show/Hide
|
C21H25N3
|
1
|
| 1 |
Ki = 1300 nM
|
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CP0467902
|
((S)-1-Benzyl-pyrrolidin-3-ylmethyl)-[2-(5-bromo-2-methoxy-phenyl)-1H-imidazol-4-ylmethyl]-amine
Show/Hide
|
C23H27BrN4O
|
1
|
| 1 |
Ki = 1300 nM
|
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CP0343243
|
3-{[4-(3,4-Dichlorophenyl)piperazin-1-yl]methyl}-2,5,7-trimethylimidazo[1,2-c]pyrimidine
Show/Hide
|
C20H23Cl2N5
|
1
|
| 1 |
Ki = 1300 nM
|
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CP0415582
|
N-[2-[4-(1H-indol-2-ylmethyl)piperazin-1-yl]ethyl]-4-methoxy-N-propylaniline
Show/Hide
|
C25H34N4O
|
1
|
| 1 |
Ki = 1300 nM
|
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CP0536408
|
1-(N-benzylanilino)-3-[3-[4-(4-iodophenyl)piperazin-1-yl]propyl]urea
Show/Hide
|
C27H32IN5O
|
1
|
| 1 |
Ki = 1300 nM
|
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CP0398979
|
2-(4-{[(2S)-8-Methyl-2,3-dihydro[1,4]dioxino[2,3-f]quinolin-2-yl]methyl}piperazin-1-yl)-quinoline-6-carbonitrile
Show/Hide
|
C27H25N5O2
|
1
|
| 1 |
Ki = 1316 nM
|
|
|
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CP0363247
|
3-methoxy-8-methyl-5,6,7,8,9,10,11,16-octahydrodibenzo[e,h]azacyclododecene
Show/Hide
|
C21H27NO
|
1
|
| 1 |
Ki = 1349 nM
|
|
|
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CP0455467
|
N-[(4-chloro-2,5-diphenylfuran-3-yl)methyl]-N',N'-diethyl-N-methylpropane-1,3-diamine
Show/Hide
|
C25H31ClN2O
|
1
|
| 1 |
Ki = 1381 nM
|
|
|
|
CP0404235
|
2-[1-(2-Chloro-benzyl)-1,2,3,6-tetrahydro-pyridin-4-yl]-benzothiazole
Show/Hide
|
C19H17ClN2S
|
1
|
| 1 |
Ki = 1400 nM
|
|
|
|
CP0376569
|
((R)-7-Dipropylamino-5,6,7,8-tetrahydro-indolizin-2-yl)-methanol
Show/Hide
|
C15H26N2O
|
2
|
| 1 |
Ki = 1400 nM
|
|
|
| 2 |
Ki = 1412.54 nM
|
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|
|
CP0374844
|
6-chloro-2-[4-(2-methoxyphenyl)piperazin-1-ylmethyl]imidazo[1,2-b]pyridazine
Show/Hide
|
C18H20ClN5O
|
1
|
| 1 |
Ki = 1400 nM
|
|
|
|
CP0267173
|
3-(2-{4-[1-(4-Fluoro-phenyl)-5-(2-methyl-2H-tetrazol-5-yl)-1H-indol-3-yl]-piperidin-1-yl}-ethyl)-oxazolidin-2-one
Show/Hide
|
C26H28FN7O2
|
1
|
| 1 |
Ki = 1400 nM
|
|
|
|
CP0481804
|
1-[3-[4-(4-bromophenyl)piperazin-1-yl]propyl]-3-[N-[(4-fluorophenyl)methyl]anilino]urea
Show/Hide
|
C27H31BrFN5O
|
1
|
| 1 |
Ki = 1400 nM
|
|
|
|
CP0505904
|
N,N-dimethyl-3-(10-methylbenzo[c]phenothiazin-7-yl)propan-1-amine
Show/Hide
|
C22H24N2S
|
1
|
| 1 |
Ki = 1419 nM
|
|
|
|
CP0375972
|
N-[4-[4-(5-methoxy-1,2-benzoxazol-3-yl)piperazin-1-yl]butyl]-3-morpholin-4-ylbenzamide
Show/Hide
|
C27H35N5O4
|
1
|
| 1 |
Ki = 1440 nM
|
|
|
|
CP0409472
|
((R)-1-Methyl-5,6,7,8-tetrahydro-indolizin-7-yl)-dipropyl-amine
Show/Hide
|
C15H26N2
|
2
|
| 1 |
Ki = 1445.44 nM
|
|
|
| 2 |
Ki = 2100 nM
|
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|
|
CP0453011
|
6-chloro-2-[4-(3,4-dichlorophenyl)piperazin-1-ylmethyl]imidazo[1,2-b]pyridazine
Show/Hide
|
C17H16Cl3N5
|
1
|
| 1 |
Ki = 1500 nM
|
|
|
|
CP0135428
|
3-{[4-(2-Methoxyphenyl)piperazin-1-yl]methyl}-5,7-dimethylimidazo[1,2-c]pyrimidine
Show/Hide
|
C20H25N5O
|
1
|
| 1 |
Ki = 1500 nM
|
|
|
|
CP0438115
|
1-(N-benzylanilino)-3-[3-[4-(4-bromophenyl)piperazin-1-yl]propyl]urea
Show/Hide
|
C27H32BrN5O
|
1
|
| 1 |
Ki = 1500 nM
|
|
|
|
CP0380757
|
1-(2-Phenyl-3H-imidazol-4-ylmethyl)-4-pyridin-2-yl-piperazine
Show/Hide
|
C19H21N5
|
1
|
| 1 |
Ki = 1530 nM
|
|
|
|
CP0875954
|
((R)-7-Dipropylamino-5,6,7,8-tetrahydro-indolizin-3-yl)-phenyl-methanone
Show/Hide
|
C21H28N2O
|
1
|
| 1 |
Ki = 1548.82 nM
|
|
|
|
CP0467864
|
6-[2-(4-methylsulfonylphenyl)ethyl]-N,N-dipropyl-1,2,3,4-tetrahydronaphthalen-2-amine
Show/Hide
|
C25H35NO2S
|
1
|
| 1 |
Ki = 1584.89 nM
|
|
|
|
CP0447841
|
3-chloro-5-ethyl-2-hydroxy-6-methoxy-N-[2-(4-phenylpiperazin-1-yl)ethyl]benzamide
Show/Hide
|
C22H28ClN3O3
|
1
|
| 1 |
Ki = 1584.89 nM
|
|
|
|
CP0847634
|
(E)-N-[4'-(Phenethylamino-methyl)-biphenyl-4-ylmethyl]-3-phenyl-N-pyridin-3-ylmethyl-acrylamide TFA
Show/Hide
|
C39H36F3N3O3
|
1
|
| 1 |
Ki = 1584.89 nM
|
|
|
|
CP0422137
|
2-[[4-(3-chlorophenyl)piperidin-1-yl]methyl]-1-methylbenzimidazole
Show/Hide
|
C20H22ClN3
|
1
|
| 1 |
Ki = 1584.89 nM
|
|
|
|
CP0439090
|
2-[[4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]piperidin-1-yl]methyl]-1-methylbenzimidazole
Show/Hide
|
C20H20ClF3N4
|
1
|
| 1 |
Ki = 1584.89 nM
|
|
|
|
CP0391410
|
2-[1-(4-Chloro-benzyl)-1,2,3,6-tetrahydro-pyridin-4-yl]-1H-benzoimidazole
Show/Hide
|
C19H18ClN3
|
1
|
| 1 |
Ki = 1600 nM
|
|
|
|
CP0420841
|
2-(1-Benzyl-1,2,3,6-tetrahydro-pyridin-4-yl)-5-chloro-benzooxazole
Show/Hide
|
C19H17ClN2O
|
1
|
| 1 |
Ki = 1600 nM
|
|
|
|
CP0520154
|
((R)-1-Benzyl-pyrrolidin-3-yl)-[2-(5-bromo-2-methoxy-phenyl)-oxazol-4-ylmethyl]-amine
Show/Hide
|
C22H24BrN3O2
|
1
|
| 1 |
Ki = 1700 nM
|
|
|
|
CP0383474
|
2-((4-phenylpiperazin-1-yl)methyl)-1H-indole-5-carbonitrile
Show/Hide
|
C20H20N4
|
1
|
| 1 |
Ki = 1700 nM
|
|
|
|
CP0528646
|
2-[4-(2-Chloro-phenyl)-piperazin-1-ylmethyl]-1H-indole-5-carbonitrile
Show/Hide
|
C20H19ClN4
|
1
|
| 1 |
Ki = 1700 nM
|
|
|
|
CP0240039
|
2-[4-(3,4-dichlorophenyl)piperazin-1-ylmethyl]imidazo[1,2-a]pyridine
Show/Hide
|
C18H18Cl2N4
|
1
|
| 1 |
Ki = 1700 nM
|
|
|
|
CP0423154
|
1-[[1-[2-(2-fluoroethoxy)ethyl]triazol-4-yl]methyl]-4-(2-methoxyphenyl)piperazine
Show/Hide
|
C18H26FN5O2
|
1
|
| 1 |
Ki = 1700 nM
|
|
|
|
CP0380080
|
1-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-4-(4-fluorophenyl)butane-1,4-dione
Show/Hide
|
C21H21ClFNO3
|
1
|
| 1 |
Ki = 1700 nM
|
|
|
|
CP0399132
|
8-hydroxy-5-[(1R)-1-hydroxy-2-[2-[3-methoxy-4-(3-phenylpropoxy)phenyl]ethylamino]ethyl]-1H-quinolin-2-one
Show/Hide
|
C29H32N2O5
|
1
|
| 1 |
Ki = 1700 nM
|
|
|
|
CP0408583
|
8-hydroxy-5-piperazin-1-yl-1H-quinolin-2-one
Show/Hide
|
C13H15N3O2
|
1
|
| 1 |
Ki = 1700 nM
|
|
|
|
CP0371910
|
3-(4-(4-(4-chlorophenyl)-1-piperazinyl)butyl)quinazolin-4(3H)-one
Show/Hide
|
C22H25ClN4O
|
1
|
| 1 |
Ki = 1780 nM
|
|
|
|
CP0404790
|
7-[4-(4-Methoxy-phenyl)-piperazin-1-ylmethyl]-4H-benzo[1,4]oxazin-3-one
Show/Hide
|
C20H23N3O3
|
1
|
| 1 |
Ki = 1790 nM
|
|
|
|
CP0484578
|
2-(1-Benzyl-1,2,3,6-tetrahydro-pyridin-4-yl)-5-chloro-benzothiazole
Show/Hide
|
C19H17ClN2S
|
1
|
| 1 |
Ki = 1800 nM
|
|
|
|
CP0480560
|
(R)-7-Dipropylamino-5,6,7,8-tetrahydro-indolizine-3-carbaldehyde
Show/Hide
|
C15H24N2O
|
2
|
| 1 |
Ki = 1800 nM
|
|
|
| 2 |
Ki = 1819.7 nM
|
|
|
|
CP0170565
|
5-(4-Phenyl-piperazin-1-ylmethyl)-1H-pyrrole-3-carbonitrile
Show/Hide
|
C16H18N4
|
1
|
| 1 |
Ki = 1800 nM
|
|
|
|
CP0528882
|
N-[(4-bromophenyl)methyl]-2-[4-(1H-indol-2-ylmethyl)piperazin-1-yl]ethanamine
Show/Hide
|
C22H27BrN4
|
1
|
| 1 |
Ki = 1800 nM
|
|
|
|
CP0468621
|
1-(N-benzylanilino)-3-[2-[4-(4-iodophenyl)piperazin-1-yl]ethyl]urea
Show/Hide
|
C26H30IN5O
|
1
|
| 1 |
Ki = 1800 nM
|
|
|
|
CP0528966
|
1-(N-benzylanilino)-3-[2-[4-(4-bromophenyl)piperazin-1-yl]ethyl]urea
Show/Hide
|
C26H30BrN5O
|
1
|
| 1 |
Ki = 1800 nM
|
|
|
|
CP0916363
|
(2H-Benzo[1,4]oxazin-3-yl)-[5-(4-pyrimidin-2-yl-piperazin-1-yl)-pentyl]-amine; compound with but-2-enedioic acid
Show/Hide
|
C25H32N6O5
|
1
|
| 1 |
Ki = 1811 nM
|
|
|
|
CP0466848
|
1-benzyl-N-[[2-(5-bromo-2-methoxyphenyl)-1,3-oxazol-4-yl]methyl]pyrrolidin-3-amine
Show/Hide
|
C22H24BrN3O2
|
1
|
| 1 |
Ki = 1850 nM
|
|
|
|
CP0442599
|
(S)-2-(5-Bromo-2-methoxy-phenyl)-4-(4-phenyl-piperazin-1-ylmethyl)-1,4,5,6-tetrahydro-pyrimidine
Show/Hide
|
C22H27BrN4O
|
1
|
| 1 |
Ki = 1900 nM
|
|
|
|
CP0192825
|
1-(4-Chlorophenyl)-4-[(1-phenyl-1H-pyrazol-4-yl)methyl]piperazine
Show/Hide
|
C20H21ClN4
|
2
|
| 1 |
Ki = 1900 nM
|
|
|
| 2 |
Ki = 1905.46 nM
|
|
|
|
CP0481803
|
1-[N-[(4-fluorophenyl)methyl]anilino]-3-[3-(4-pyrimidin-2-ylpiperazin-1-yl)propyl]urea
Show/Hide
|
C25H30FN7O
|
1
|
| 1 |
Ki = 1900 nM
|
|
|
|
CP0883149
|
((S)-7-Dipropylamino-5,6,7,8-tetrahydro-indolizin-3-yl)-phenyl-methanone
Show/Hide
|
C21H28N2O
|
1
|
| 1 |
Ki = 1905.46 nM
|
|
|
|
CP0332842
|
6-[[1-[2-(7-chloro-2-methylquinolin-5-yl)oxyethyl]piperidin-4-yl]methyl]-7-fluoro-4H-1,4-benzoxazin-3-one
Show/Hide
|
C26H27ClFN3O3
|
1
|
| 1 |
Ki = 1995.26 nM
|
|
|
|
CP0399598
|
2-[(4S,5R)-9-(benzenesulfonyl)-4-(methylamino)-9-azatricyclo[6.3.0.03,6]undeca-1,3(6),7,10-tetraen-5-yl]ethanol
Show/Hide
|
C19H20N2O3S
|
1
|
| 1 |
Ki = 1995.26 nM
|
|
|
|
CP0381010
|
3-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-7-trimethylsilanyl-pyrazolo[1,5-a]pyridine
Show/Hide
|
C21H27ClN4Si
|
1
|
| 1 |
Ki = 2000 nM
|
|
|
|
CP0249081
|
2-{4-[3-(4-Methyl-piperazin-1-yl)-propoxy]-phenyl}-1H-benzoimidazole
Show/Hide
|
C21H26N4O
|
1
|
| 1 |
Ki = 2000 nM
|
|
|
|
CP0536912
|
1-(N-benzylanilino)-3-[3-(4-pyrimidin-2-ylpiperazin-1-yl)propyl]urea
Show/Hide
|
C25H31N7O
|
1
|
| 1 |
Ki = 2000 nM
|
|
|
|
CP0401061
|
1-Phenyl-4-(2-phenyl-thiazol-4-ylmethyl)-piperazine
Show/Hide
|
C20H21N3S
|
1
|
| 1 |
Ki = 2050 nM
|
|
|
|
CP0382593
|
7-methyl-6,7,8,9,14,15-hexahydro-5H-indolo[3,2-f][3]benzazecin-3-ol
Show/Hide
|
C20H22N2O
|
1
|
| 1 |
Ki = 2070 nM
|
|
|
|
CP0847016
|
(7R)-3-[(1E)-(hydroxyimino)methyl]-N,N-dipropyl-5,6,7,8-tetrahydroindolizin-7-amine
Show/Hide
|
C15H25N3O
|
1
|
| 1 |
Ki = 2089.3 nM
|
|
|
|
CP0453020
|
2-[4-(2-methoxyphenyl)piperazin-1-ylmethyl]-6-methyl-8-morpholinoimidazo[1,2-a]pyridine
Show/Hide
|
C24H31N5O2
|
1
|
| 1 |
Ki = 2100 nM
|
|
|
|
CP0277576
|
1-(2-{4-[1-(4-Fluoro-phenyl)-5-(1-methyl-1H-pyrazol-3-yl)-1H-indol-3-yl]-piperidin-1-yl}-ethyl)-imidazolidin-2-one
Show/Hide
|
C28H31FN6O
|
1
|
| 1 |
Ki = 2100 nM
|
|
|
|
CP0436141
|
1-(4-(1H-pyrazol-1-yl)benzyl)-4-phenylpiperazine
Show/Hide
|
C20H22N4
|
1
|
| 1 |
Ki = 2100 nM
|
|
|
|
CP0051911
|
(5R)-N,N-dipropyl-4,5,6,7-tetrahydropyrazolo[1,5-a]pyridin-5-amine
Show/Hide
|
C13H23N3
|
3
|
| 1 |
Ki = 2100 nM
|
|
|
| 2 |
Ki = 2700 nM
|
|
|
| 3 |
Ki = 4300 nM
|
|
|
|
CP0372225
|
(4aR,11bR)-9-methyl-4-propyl-3,4a,5,6,8,11b-hexahydro-2H-isoindolo[5,6-h][1,4]benzoxazin-10-one
Show/Hide
|
C18H24N2O2
|
1
|
| 1 |
Ki = 2187.76 nM
|
|
|
|
CP0405191
|
2-[4-(pyrazolo[1,5-a]pyridin-3-ylmethyl)piperazin-1-yl]phenol
Show/Hide
|
C18H20N4O
|
1
|
| 1 |
Ki = 2200 nM
|
|
|
|
CP0046178
|
N-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl]-4-[1-(4-nitrophenyl)triazol-4-yl]butanamide
Show/Hide
|
C26H31Cl2N7O3
|
1
|
| 1 |
Ki = 2200 nM
|
|
|
|
CP0384609
|
4-[(1R)-1-hydroxy-2-[2-(2-methoxyphenoxy)ethylamino]ethyl]benzene-1,2-diol
Show/Hide
|
C17H21NO5
|
1
|
| 1 |
Ki = 2200 nM
|
|
|
|
CP0046420
|
CAS_3853
Show/Hide
|
C18H19ClN4
|
5
|
| 1 |
Ki = 2300 nM
|
|
|
| 2 |
Ki = 22000 nM
|
|
|
| 3 |
Ki = 30902.95 nM
|
|
|
| 4 |
Ki = 65000 nM
|
|
|
| 5 |
Ki > 3030 nM
|
|
|
|
CP0467945
|
(1-Benzyl-piperidin-4-yl)-(2-phenyl-thiazol-4-ylmethyl)-amine
Show/Hide
|
C22H25N3S
|
1
|
| 1 |
Ki = 2300 nM
|
|
|
|
CP0410996
|
4-bromo-N-[2-[4-(1H-indol-2-ylmethyl)piperazin-1-yl]ethyl]aniline
Show/Hide
|
C21H25BrN4
|
1
|
| 1 |
Ki = 2300 nM
|
|
|
|
CP0277805
|
5-phenyl-N-(4-(4-(3-(trifluoromethyl)phenyl)piperazin-1-yl)butyl)oxazol-2-amine
Show/Hide
|
C24H27F3N4O
|
1
|
| 1 |
Ki = 2322 nM
|
|
|
|
CP0503881
|
N-[4-[4-(N-acetyl-2-methoxyanilino)piperidin-1-yl]butyl]naphthalene-2-carboxamide
Show/Hide
|
C29H35N3O3
|
1
|
| 1 |
Ki = 2340 nM
|
|
|
|
CP0383464
|
2-[4-(4-Phenyl-piperazin-1-ylmethyl)-1H-pyrrol-2-ylmethylene]-malononitrile
Show/Hide
|
C19H19N5
|
1
|
| 1 |
Ki = 2350 nM
|
|
|
|
CP0911241
|
((R)-3-Phenyl-5,6,7,8-tetrahydro-indolizin-7-yl)-dipropyl-amine
Show/Hide
|
C20H28N2
|
1
|
| 1 |
Ki = 2398.83 nM
|
|
|
|
CP0374896
|
2-[4-(2-methoxyphenyl)piperazin-1-ylmethyl]-6-methyl-8-(pyrazol-1-yl)imidazo[1,2-a]pyridine
Show/Hide
|
C23H26N6O
|
1
|
| 1 |
Ki = 2400 nM
|
|
|
|
CP0381332
|
1-(4-Fluoro-phenyl)-4-(3,4,6,7,8,12c-hexahydro-1H-pyrazino[1',2':1,2]pyrido[4,3-b]indol-2-yl)-butan-1-ol
Show/Hide
|
C24H28FN3O
|
1
|
| 1 |
Ki = 2412 nM
|
|
|
|
CP0125484
|
4-phenyl-N-(4-(4-(3-(trifluoromethyl)phenyl)piperazin-1-yl)butyl)thiazol-2-amine
Show/Hide
|
C24H27F3N4S
|
1
|
| 1 |
Ki = 2431 nM
|
|
|
|
CP0434838
|
(4aS,10bS)-4-propyl-2,3,4a,5,6,10b-hexahydrobenzo[h][1,4]benzoxazine-9-carboxamide
Show/Hide
|
C16H22N2O2
|
1
|
| 1 |
Ki = 2454.71 nM
|
|
|
|
CP0439833
|
6-(4-p-Tolyl-piperazin-1-ylmethyl)-4H-benzo[1,4]oxazin-3-one
Show/Hide
|
C20H23N3O2
|
1
|
| 1 |
Ki = 2490 nM
|
|
|
|
CP0422264
|
1-(1-Benzyl-piperidin-4-yl)-1H-pyrrole-2-carbaldehyde
Show/Hide
|
C17H20N2O
|
1
|
| 1 |
Ki = 2500 nM
|
|
|
|
CP0096286
|
(R)-3-(2-(2-(4-methylpiperidin-1-yl)ethyl)pyrrolidin-1-ylsulfonyl)phenol
Show/Hide
|
C18H28N2O3S
|
1
|
| 1 |
Ki = 2511.89 nM
|
|
|
|
CP0111551
|
5-chloro-N-(4-piperazin-1-ylquinolin-6-yl)naphthalene-2-sulfonamide
Show/Hide
|
C23H21ClN4O2S
|
1
|
| 1 |
Ki = 2511.89 nM
|
|
|
|
CP0875955
|
1-((R)-7-Dipropylamino-5,6,7,8-tetrahydro-indolizin-3-yl)-2,2,2-trifluoro-ethanone
Show/Hide
|
C16H23F3N2O
|
1
|
| 1 |
Ki = 2511.89 nM
|
|
|
|
CP0104629
|
(3-((4-(4-chlorophenyl)piperazin-1-yl)methyl)H-pyrazolo[1,5-a]pyridin-6-yl)methanol
Show/Hide
|
C19H21ClN4O
|
2
|
| 1 |
Ki = 2570.4 nM
|
|
|
| 2 |
Ki = 2600 nM
|
|
|
|
CP0391923
|
1-Benzyl-4-(2-iodo-pyrrol-1-yl)-piperidine
Show/Hide
|
C16H19IN2
|
1
|
| 1 |
Ki = 2600 nM
|
|
|
|
CP0494156
|
1-[1-Heptyl-4-(3-hydroxy-phenyl)-piperidin-4-yl]-propan-1-one
Show/Hide
|
C21H33NO2
|
1
|
| 1 |
Ki = 2615 nM
|
|
|
|
CP0389485
|
ethyl (4aR,10bR)-4-propyl-2,3,4a,5,6,10b-hexahydrobenzo[h][1,4]benzoxazine-9-carboxylate
Show/Hide
|
C18H25NO3
|
1
|
| 1 |
Ki = 2630.27 nM
|
|
|
|
CP0401624
|
3-[2-(4-Phenyl-piperazin-1-yl)-ethyl]-2,3-dihydro-isoindol-1-one
Show/Hide
|
C20H23N3O
|
1
|
| 1 |
Ki = 2682 nM
|
|
|
|
CP0468119
|
3-{2-[4-(3,4-Dimethyl-phenyl)-piperazin-1-yl]-ethyl}-2,3-dihydro-isoindol-1-one
Show/Hide
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C22H27N3O
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1
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| 1 |
Ki = 2682 nM
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CP0405787
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3-[[4-(4-chlorophenyl)piperazin-1-yl]methyl]-7-iodopyrazolo[1,5-a]pyridine
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C18H18ClIN4
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1
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| 1 |
Ki = 2691.53 nM
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CP0342253
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3-Methyl-2-morpholin-4-yl-7-[(4-phenylpiperazin-1-yl)methyl]-3,5-dihydro-4H-pyrrolo[3,2-d]pyrimidin-4-one
Show/Hide
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C22H28N6O2
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1
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| 1 |
Ki = 2700 nM
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CP0422127
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(4aR,10bR)-N-(4-methoxyphenyl)-4-propyl-2,3,4a,5,6,10b-hexahydrobenzo[h][1,4]benzoxazine-9-carboxamide
Show/Hide
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C23H28N2O3
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1
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| 1 |
Ki = 2754.23 nM
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CP0134581
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3-(2-{4-[1-(4-Fluoro-phenyl)-5-pyrimidin-2-yl-1H-indol-3-yl]-piperidin-1-yl}-ethyl)-oxazolidin-2-one
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C28H28FN5O2
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1
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| 1 |
Ki = 2800 nM
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CP0423155
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1-[[1-[4-(3-fluoropropoxy)phenyl]triazol-4-yl]methyl]-4-(2-methoxyphenyl)piperazine
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C23H28FN5O2
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1
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| 1 |
Ki = 2800 nM
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CP0477396
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8-(4-propylpiperazin-1-yl)-2,3-dihydro-1,4-benzodioxin-5-ol
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C15H22N2O3
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1
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| 1 |
Ki = 2800 nM
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CP0916902
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1-((R)-7-Dipropylamino-5,6,7,8-tetrahydro-indolizin-3-yl)-ethanone
Show/Hide
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C16H26N2O
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1
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| 1 |
Ki = 2818.38 nM
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CP0932643
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(R)-7-Dipropylamino-5,6,7,8-tetrahydro-indolizine-3-carbonitrile
Show/Hide
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C15H23N3
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1
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| 1 |
Ki = 2818.38 nM
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CP0430505
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2-(1-Benzyl-1,2,3,6-tetrahydro-pyridin-4-yl)-5-chloro-1H-benzoimidazole
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C19H18ClN3
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1
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| 1 |
Ki = 2900 nM
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CP0151333
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1-(2-{4-[1-(4-Fluoro-phenyl)-5-(1-methyl-1H-[1,2,4]triazol-3-yl)-1H-indol-3-yl]-piperidin-1-yl}-ethyl)-imidazolidin-2-one
Show/Hide
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C27H30FN7O
|
1
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| 1 |
Ki = 2900 nM
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CP0371852
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2-(4-((1-phenyl-1H-pyrazol-4-yl)methyl)piperazin-1-yl)pyrimidine
Show/Hide
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C18H20N6
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1
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| 1 |
Ki = 2900 nM
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CP0461941
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1-[[1-[4-[3-(2-fluoroethoxy)propoxy]phenyl]triazol-4-yl]methyl]-4-(2-methoxyphenyl)piperazine
Show/Hide
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C25H32FN5O3
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1
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| 1 |
Ki = 2900 nM
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CP0464436
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2-[4-(5-Methyl-2-phenyl-3H-imidazol-4-ylmethyl)-piperazin-1-yl]-pyrimidine
Show/Hide
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C19H22N6
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1
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| 1 |
Ki = 2980 nM
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CP0406355
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2-(4-Phenyl-piperazin-1-ylmethyl)-1H-indole-6-carbonitrile
Show/Hide
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C20H20N4
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1
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| 1 |
Ki = 3100 nM
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CP0430726
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3-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-2-methyl-7-phenyl-pyrazolo[1,5-a]pyridine
Show/Hide
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C25H25ClN4
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1
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| 1 |
Ki = 3100 nM
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CP0449394
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2-[4-(4-fluorophenyl)piperazin-1-ylmethyl]imidazo[1,2-a]pyridine
Show/Hide
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C18H19FN4
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1
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| 1 |
Ki = 3100 nM
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CP0343878
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3-(2-{4-[1-(4-Fluoro-phenyl)-5-(1-methyl-1H-[1,2,4]triazol-3-yl)-1H-indol-3-yl]-piperidin-1-yl}-ethyl)-oxazolidin-2-one
Show/Hide
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C27H29FN6O2
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1
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| 1 |
Ki = 3100 nM
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CP0342252
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3-{[4-(4-Chlorophenyl)piperazin-1-yl]methyl}-2,5,7-trimethylimidazo[1,2-c]pyrimidine
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C20H24ClN5
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1
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| 1 |
Ki = 3100 nM
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CP0040677
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12-methoxy-7-methyl-6,7,8,9,10,15-hexahydro-5H-dibenzo[d,g]azacycloundecene
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C20H25NO
|
1
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| 1 |
Ki = 3136 nM
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CP0383488
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4-[2-[6-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-2-yl]ethyl]benzoic acid
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C25H33NO2
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1
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| 1 |
Ki = 3162.28 nM
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CP0466962
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(2R,8S)-12-(benzenesulfonyl)-5,12-diazatetracyclo[7.7.0.02,8.011,15]hexadeca-1(9),10,13,15-tetraene
Show/Hide
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C20H20N2O2S
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1
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| 1 |
Ki = 3162.28 nM
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CP0381041
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(R)-2-Phenyl-5-(4-phenyl-piperazin-1-yl)-4,5,6,7-tetrahydro-1H-[1,3]diazepine
Show/Hide
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C21H26N4
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1
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| 1 |
Ki = 3300 nM
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CP0389484
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(4aR,10bR)-4-propyl-2,3,4a,5,6,10b-hexahydrobenzo[h][1,4]benzoxazine-9-carboxylic acid
Show/Hide
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C16H21NO3
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1
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| 1 |
Ki = 3311.31 nM
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CP0422361
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4-[4-(pyrazolo[1,5-a]pyridin-3-ylmethyl)piperazin-1-yl]phenol
Show/Hide
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C18H20N4O
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1
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| 1 |
Ki = 3400 nM
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CP0496938
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2-[[4-(6-fluoropyridin-2-yl)piperazin-1-yl]methyl]pyrazolo[1,5-a]pyridine
Show/Hide
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C17H18FN5
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1
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| 1 |
Ki = 3400 nM
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CP0167456
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3-{[4-(2-Methoxyphenyl)piperazin-1-yl]methyl}-2,5,7-trimethylimidazo[1,2-c]pyrimidine
Show/Hide
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C21H27N5O
|
1
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| 1 |
Ki = 3400 nM
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CP0895458
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(2H-Benzo[1,4]oxazin-3-yl)-[3-(4-phenyl-piperazin-1-yl)-propyl]-amine; compound with but-2-enedioic acid
Show/Hide
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C25H30N4O5
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1
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| 1 |
Ki = 3437 nM
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CP0374897
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2-[4-(2-methoxyphenyl)piperazin-1-ylmethyl]-6-methylimidazo[1,2-a]pyridine-8-carbonitrile
Show/Hide
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C21H23N5O
|
1
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| 1 |
Ki = 3500 nM
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CP0388360
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N-[3-[(5-chloro-6-oxo-4-piperazin-1-ylpyridazin-1-yl)methyl]-2-methylphenyl]-4-phenylbenzamide
Show/Hide
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C29H28ClN5O2
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1
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| 1 |
Ki = 3548.13 nM
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CP0406351
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(S)-7-Dipropylamino-5,6,7,8-tetrahydro-indolizine-1-carbaldehyde
Show/Hide
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C15H24N2O
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2
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| 1 |
Ki = 3600 nM
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| 2 |
Ki = 3630.78 nM
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CP0916907
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((S)-3-Dimethylaminomethyl-5,6,7,8-tetrahydro-indolizin-7-yl)-dipropyl-amine
Show/Hide
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C17H31N3
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1
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| 1 |
Ki = 3630.78 nM
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CP0324173
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3-((4-(4-chlorophenyl)piperazin-1-yl)methyl)-7-methylH-pyrazolo[1,5-a]pyridine
Show/Hide
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C19H21ClN4
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2
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| 1 |
Ki = 3715.35 nM
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| 2 |
Ki = 3800 nM
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CP0442588
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3-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-7-(4-fluoro-phenyl)-2-methyl-pyrazolo[1,5-a]pyridine
Show/Hide
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C25H24ClFN4
|
1
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| 1 |
Ki = 3800 nM
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CP0084794
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3-((4-(4-chlorophenyl)piperazin-1-yl)methyl)H-pyrazolo[1,5-a]pyridine
Show/Hide
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C18H19ClN4
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3
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| 1 |
Ki = 3890.45 nM
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| 2 |
Ki = 4500 nM
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| 3 |
Ki = 5000 nM
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CP0036418
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3-[4-(4-Methoxy-phenyl)-piperazin-1-ylmethyl]-1H-pyrrolo[2,3-b]pyridine
Show/Hide
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C19H22N4O
|
1
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| 1 |
Ki = 3900 nM
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CP0058895
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2-[4-(2-methoxyphenyl)piperazin-1-ylmethyl]imidazo[1,2-a]pyridine
Show/Hide
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C19H22N4O
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1
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| 1 |
Ki = 3900 nM
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CP0418859
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1-Phenyl-4-(2-phenyl-oxazol-4-ylmethyl)-piperazine
Show/Hide
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C20H21N3O
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1
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| 1 |
Ki = 3950 nM
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CP0346837
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8-methyl-5,6,7,8,9,10,11,16-octahydrodibenzo[e,h]azacyclododecene-3-ol
Show/Hide
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C20H25NO
|
1
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| 1 |
Ki = 3964 nM
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CP0156235
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3,N-Dimethyl-N-[(R)-1-methyl-3-(4-methyl-piperidin-1-yl)-propyl]-benzenesulfonamide
Show/Hide
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C18H30N2O2S
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1
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| 1 |
Ki = 3981.07 nM
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CP0371948
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8-fluoro-6-[[1-[2-(7-fluoro-2-methylquinolin-5-yl)oxyethyl]piperidin-4-yl]methyl]-4H-1,4-benzoxazin-3-one
Show/Hide
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C26H27F2N3O3
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1
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| 1 |
Ki = 3981.07 nM
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CP0469995
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3-[1-[(1-methylbenzimidazol-2-yl)methyl]piperidin-4-yl]-1,2-benzothiazole
Show/Hide
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C21H22N4S
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1
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| 1 |
Ki = 3981.07 nM
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CP0167459
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2,5,7-Trimethyl-3-[4-(phenylpiperazin-1-yl)methyl]imidazo[1,2-c]pyrimidine
Show/Hide
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C20H25N5
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1
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| 1 |
Ki = 4200 nM
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CP0433365
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2-[4-(1H-indol-2-ylmethyl)piperazin-1-yl]-N-[(4-methoxyphenyl)methyl]ethanamine
Show/Hide
|
C23H30N4O
|
1
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| 1 |
Ki = 4300 nM
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CP0875956
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(S)-7-Dipropylamino-5,6,7,8-tetrahydro-indolizine-3-carboxylic acid ethyl ester
Show/Hide
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C17H28N2O2
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1
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| 1 |
Ki = 4365.16 nM
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CP0391409
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2-(1-Benzyl-1,2,3,6-tetrahydro-pyridin-4-yl)-1H-benzoimidazole
Show/Hide
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C19H19N3
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1
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| 1 |
Ki = 4400 nM
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CP0451179
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3-(4-Phenyl-piperazin-1-ylmethyl)-1H-indole-5-carbonitrile
Show/Hide
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C20H20N4
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1
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| 1 |
Ki = 4400 nM
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CP0487544
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2-(1-Benzyl-1,2,3,6-tetrahydro-pyridin-4-yl)-benzooxazole
Show/Hide
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C19H18N2O
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1
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| 1 |
Ki = 4500 nM
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CP0178941
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3-((4-(4-chlorophenyl)piperazin-1-yl)methyl)-7-ethynyl-pyrazolo[1,5-a]pyridine
Show/Hide
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C20H19ClN4
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2
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| 1 |
Ki = 4570.88 nM
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| 2 |
Ki = 4600 nM
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CP0541163
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N-[2-[4-(1H-indol-2-ylmethyl)piperazin-1-yl]ethyl]-N-[(4-methoxyphenyl)methyl]propan-1-amine
Show/Hide
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C26H36N4O
|
1
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| 1 |
Ki = 4600 nM
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CP0068209
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4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;hydrochloride
Show/Hide
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C11H17NO3
|
1
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| 1 |
Ki = 4700 nM
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CP0159532
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N-[[4-(2-cyanophenyl)piperazin-1-yl]methyl]-3-methylbenzamide
Show/Hide
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C20H22N4O
|
1
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| 1 |
Ki = 4700 nM
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CP0916904
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(7R)-3-[(1Z)-(hydroxyimino)methyl]-N,N-dipropyl-5,6,7,8-tetrahydroindolizin-7-amine
Show/Hide
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C15H25N3O
|
1
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| 1 |
Ki = 4786.3 nM
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CP0234177
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2-[[4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl]methyl]-1-methylbenzimidazole
Show/Hide
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C19H19ClF3N5
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1
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| 1 |
Ki = 5011.87 nM
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CP0425965
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2-[1-(1-Benzyl-piperidin-4-yl)-1H-pyrrol-2-ylmethylene]-malononitrile
Show/Hide
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C20H20N4
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1
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| 1 |
Ki = 5100 nM
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CP0461940
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1-[[1-[2-[2-(2-fluoroethoxy)ethoxy]ethyl]triazol-4-yl]methyl]-4-(2-methoxyphenyl)piperazine
Show/Hide
|
C20H30FN5O3
|
1
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| 1 |
Ki = 5100 nM
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CP0449027
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3-[4-(4-Fluoro-phenyl)-piperazin-1-ylmethyl]-1H-indole-5-carbonitrile
Show/Hide
|
C20H19FN4
|
1
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| 1 |
Ki = 5200 nM
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CP0052067
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2-((4-(4-chlorophenyl)piperazin-1-yl)methyl)-pyrazolo[1,5-a]pyridine
Show/Hide
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C18H19ClN4
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2
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| 1 |
Ki = 5248.07 nM
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| 2 |
Ki = 5300 nM
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CP0464731
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2-[5-(4-Phenyl-piperazin-1-ylmethyl)-1H-pyrrol-2-ylmethylene]-malononitrile
Show/Hide
|
C19H19N5
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1
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| 1 |
Ki = 5250 nM
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CP0382905
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1-Benzyl-4-(2-phenyl-thiazol-4-ylmethyl)-piperazine
Show/Hide
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C21H23N3S
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1
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| 1 |
Ki = 5250 nM
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CP0403425
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3-(1H-imidazol-1-yl)-N-(4-(4-(5-methoxybenzo[d]isoxazol-3-yl)piperazin-1-yl)butyl)benzamide
Show/Hide
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C26H30N6O3
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1
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| 1 |
Ki = 5539 nM
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CP0425377
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6-chloro-2-[4-(4-fluorophenyl)piperazin-1-ylmethyl]imidazo[1,2-b]pyridazine
Show/Hide
|
C17H17ClFN5
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1
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| 1 |
Ki = 5600 nM
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CP0439308
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3-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-7-(4-fluoro-phenyl)-pyrazolo[1,5-a]pyridine
Show/Hide
|
C24H22ClFN4
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1
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| 1 |
Ki = 5700 nM
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CP0423153
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(2R,3S,4S,5R)-5-fluoro-2-(hydroxymethyl)-6-[3-[4-[4-[[4-(2-methoxyphenyl)piperazin-1-yl]methyl]triazol-1-yl]phenoxy]propoxy]oxane-3,4-diol
Show/Hide
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C29H38FN5O7
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1
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| 1 |
Ki = 5700 nM
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CP0454857
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((S)-1-Benzyl-pyrrolidin-3-ylmethyl)-[2-(4-bromo-1-methoxy-naphthalen-2-yl)-oxazol-4-ylmethyl]-amine
Show/Hide
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C27H28BrN3O2
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1
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| 1 |
Ki = 5850 nM
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CP0480184
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3-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-pyrazolo[1,5-a]pyridine-7-carbaldehyde
Show/Hide
|
C19H19ClN4O
|
1
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| 1 |
Ki = 5900 nM
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CP0910274
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2-((R)-7-Dipropylamino-5,6,7,8-tetrahydro-indolizin-3-ylmethylene)-malononitrile
Show/Hide
|
C18H24N4
|
1
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| 1 |
Ki = 6025.6 nM
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CP0436855
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(1-Benzyl-piperidin-4-yl)-(2-phenyl-oxazol-4-ylmethyl)-amine
Show/Hide
|
C22H25N3O
|
1
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| 1 |
Ki = 6100 nM
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CP0135427
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7-Chloro-3-[(4-phenylpiperazin-1-yl)methyl]-1Hpyrrolo[2,3-c]pyridine
Show/Hide
|
C18H19ClN4
|
1
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| 1 |
Ki = 6100 nM
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CP0330237
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5-((4-(2-methoxyphenyl)piperazin-1-yl)methyl)-N,N,6-trimethyl-7H-pyrrolo[2,3-d]pyrimidin-2-amine
Show/Hide
|
C21H28N6O
|
1
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| 1 |
Ki = 6100 nM
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CP0378665
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7-methyl-6,7,8,9,10,15-hexahydro-5H-dibenzo[d,g]azacycloundecene-12-ol
Show/Hide
|
C19H23NO
|
1
|
| 1 |
Ki = 6122 nM
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CP0401667
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3-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-1H-indole-5-carbonitrile
Show/Hide
|
C20H19ClN4
|
1
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| 1 |
Ki = 6400 nM
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CP0345574
|
3-(4-Methyl-piperidin-1-ylmethyl)-1H-indole
Show/Hide
|
C15H20N2
|
1
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| 1 |
Ki = 6700 nM
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CP0454824
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1-Benzyl-4-(3-oxazol-5-yl-pyrrol-1-yl)-piperidine
Show/Hide
|
C19H21N3O
|
1
|
| 1 |
Ki = 6800 nM
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CP0286303
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6,7,8,9,10,15-hexahydro-5H-dibenzo[d,g]azacycloundecin-12-ol
Show/Hide
|
C18H21NO
|
1
|
| 1 |
Ki = 6896 nM
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CP0375010
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2-{4-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-1H-pyrrol-2-ylmethylene}-malononitrile
Show/Hide
|
C19H18ClN5
|
1
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| 1 |
Ki = 6950 nM
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CP0393315
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2-[3-(4-Phenyl-piperazin-1-ylmethyl)-1H-pyrrol-2-ylmethylene]-malononitrile
Show/Hide
|
C19H19N5
|
1
|
| 1 |
Ki = 6950 nM
|
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CP0401144
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2-[1-(1-Benzyl-piperidin-4-yl)-1H-pyrrol-3-ylmethylene]-malononitrile
Show/Hide
|
C20H20N4
|
1
|
| 1 |
Ki = 7000 nM
|
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CP0375964
|
(R)-2-(5-Bromo-2-methoxy-phenyl)-4-(4-phenyl-piperazin-1-ylmethyl)-1,4,5,6-tetrahydro-pyrimidine
Show/Hide
|
C22H27BrN4O
|
1
|
| 1 |
Ki = 7400 nM
|
|
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CP0437589
|
2-{3-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-1H-pyrrol-2-ylmethylene}-malononitrile
Show/Hide
|
C19H18ClN5
|
1
|
| 1 |
Ki = 7600 nM
|
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CP0504999
|
4-Bromo-2-[4-(4-phenyl-piperazin-1-ylmethyl)-oxazol-2-yl]-phenol
Show/Hide
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C20H20BrN3O2
|
1
|
| 1 |
Ki = 7600 nM
|
|
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CP0391221
|
1-[[1-[2-[2-[2-(2-fluoroethoxy)ethoxy]ethoxy]ethyl]triazol-4-yl]methyl]-4-(2-methoxyphenyl)piperazine
Show/Hide
|
C22H34FN5O4
|
1
|
| 1 |
Ki = 7600 nM
|
|
|
|
CP0469565
|
1-Benzyl-4-(2-trimethylsilanylethynyl-pyrrol-1-yl)-piperidine
Show/Hide
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C21H28N2Si
|
1
|
| 1 |
Ki = 7700 nM
|
|
|
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CP0453012
|
6-chloro-2-[4-(4-chlorophenyl)piperazin-1-ylmethyl]imidazo[1,2-b]pyridazine
Show/Hide
|
C17H17Cl2N5
|
1
|
| 1 |
Ki = 7700 nM
|
|
|
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CP0448425
|
1-Benzyl-4-(2-ethynyl-pyrrol-1-yl)-piperidine
Show/Hide
|
C18H20N2
|
1
|
| 1 |
Ki = 7900 nM
|
|
|
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CP0915683
|
((S)-3-Phenyl-5,6,7,8-tetrahydro-indolizin-7-yl)-dipropyl-amine
Show/Hide
|
C20H28N2
|
1
|
| 1 |
Ki = 7943.28 nM
|
|
|
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CP0466278
|
1-Benzyl-4-(2-phenyl-oxazol-4-ylmethyl)-piperazine
Show/Hide
|
C21H23N3O
|
1
|
| 1 |
Ki = 8400 nM
|
|
|
|
CP0391307
|
((S)-7-Dipropylamino-5,6,7,8-tetrahydro-indolizin-2-yl)-methanol
Show/Hide
|
C15H26N2O
|
2
|
| 1 |
Ki = 8511.38 nM
|
|
|
| 2 |
Ki = 8600 nM
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CP0377732
|
1-Benzyl-4-(2-phenylethynyl-pyrrol-1-yl)-piperidine
Show/Hide
|
C24H24N2
|
1
|
| 1 |
Ki = 8700 nM
|
|
|
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CP0530017
|
3-[[4-[4-(2-fluoroethoxy)phenyl]piperazin-1-yl]methyl]pyrazolo[1,5-a]pyridine
Show/Hide
|
C20H23FN4O
|
1
|
| 1 |
Ki = 8700 nM
|
|
|
|
CP0129571
|
2-[4-(4-chlorophenyl)piperazin-1-yl)methyl]imidazo[1,2-a]pyridine
Show/Hide
|
C18H19ClN4
|
1
|
| 1 |
Ki = 8800 nM
|
|
|
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CP0420836
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3-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-4-methyl-pyrazolo[1,5-a]pyridine
Show/Hide
|
C19H21ClN4
|
1
|
| 1 |
Ki = 9400 nM
|
|
|
|
CP0391290
|
((S)-7-Dipropylamino-5,6,7,8-tetrahydro-indolizin-1-yl)-methanol
Show/Hide
|
C15H26N2O
|
2
|
| 1 |
Ki = 9700 nM
|
|
|
| 2 |
Ki = 9772.37 nM
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CP0049257
|
3-Benzyl-5-butyl-[1,3,5]thiadiazinane-2-thione
Show/Hide
|
C14H20N2S2
|
1
|
| 1 |
Ki = 10000 nM
|
|
|
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CP0382331
|
2-(4-Pentyl-piperazin-1-yl)-1,4-diphenyl-butane-1,4-dione
Show/Hide
|
C25H32N2O2
|
1
|
| 1 |
Ki = 10000 nM
|
|
|
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CP0402038
|
3-[(1,3-Dioxo-1,3-dihydro-isoindol-2-ylmethyl)-(3-morpholin-4-yl-propyl)-amino]-propionitrile
Show/Hide
|
C19H24N4O3
|
1
|
| 1 |
Ki = 10000 nM
|
|
|
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CP0405718
|
N-(9-ethylcarbazol-3-yl)-N',N'-dimethylpropane-1,3-diamine
Show/Hide
|
C19H25N3
|
1
|
| 1 |
Ki = 10000 nM
|
|
|
|
CP0428780
|
3-[(1,3-Dioxo-1,3-dihydro-isoindol-2-ylmethyl)-propyl-amino]-propionitrile
Show/Hide
|
C15H17N3O2
|
1
|
| 1 |
Ki = 10000 nM
|
|
|
|
CP0461838
|
2-Dipropylaminomethyl-isoindole-1,3-dione
Show/Hide
|
C15H20N2O2
|
1
|
| 1 |
Ki = 10000 nM
|
|
|
|
CP0465320
|
3-Dibutylaminomethyl-7-methoxy-2-methyl-quinolin-4-ol
Show/Hide
|
C20H30N2O2
|
1
|
| 1 |
Ki = 10000 nM
|
|
|
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CP0467573
|
Aceperone
Show/Hide
|
C24H29FN2O2
|
1
|
| 1 |
Ki = 10000 nM
|
|
|
|
CP0511655
|
(3,5-Dibutyl-[1,3,5]triazinan-1-yl)-(2,6-dichloro-phenyl)-methanethione
Show/Hide
|
C18H27Cl2N3S
|
1
|
| 1 |
Ki = 10000 nM
|
|
|
|
CP0514057
|
1-Phenethyl-piperidine-3-carboxylic acid (4-ethoxy-phenyl)-amide
Show/Hide
|
C22H28N2O2
|
1
|
| 1 |
Ki = 10000 nM
|
|
|
|
CP0514058
|
2-(2-Pyridin-4-yl-ethyl)-1,2,3,4,6,7,8,12c-octahydro-pyrazino[1',2':1,2]pyrido[4,3-b]indole
Show/Hide
|
C21H24N4
|
1
|
| 1 |
Ki = 10000 nM
|
|
|
|
CP0534109
|
[3-methyl-1-(3-oxo-3-phenylpropyl)-4-phenylpiperidin-4-yl] propanoate
Show/Hide
|
C24H29NO3
|
1
|
| 1 |
Ki = 10000 nM
|
|
|
|
CP0939908
|
3-{1-[(Butyl-ethyl-amino)-methyl]-2-oxo-propyl}-4-hydroxy-4a,8a-dihydro-chromen-2-one
Show/Hide
|
C19H27NO4
|
1
|
| 1 |
Ki = 10000 nM
|
|
|
|
CP0040673
|
2-[2-(3-chloro-4-methoxyphenyl)ethyl]-2,3,4,5-tetrahydro-1H-2-benzazepine
Show/Hide
|
C19H22ClNO
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0040675
|
3-methoxy-6,7,9,10,11,15b-hexahydro-5H-[2]benzazepino[1,2-a][2]benzazepine
Show/Hide
|
C20H23NO
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0277604
|
3-chloro-2-methoxy-5,6,8,9,10,14b-hexahydroisoquino[1,2-a][2]benzazepine
Show/Hide
|
C19H20ClNO
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0287080
|
3-methoxy-5,8,9,13b-tetrahydro-6H-isoquino-[1,2-a]isoquinoline
Show/Hide
|
C18H19NO
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
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CP0375574
|
6-Methoxy-2-methyl-1-(2-methylbenzyl)-1,2,3,4-tetrahydroisoquinoline
Show/Hide
|
C19H23NO
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0375575
|
6-Methyl-5,6,7,8,9,14-hexahydrodibenzo[c,f]azecin-11-ol
Show/Hide
|
C18H21NO
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0375577
|
10-methyl-17,19-dioxa-10-azatetracyclo[12.7.0.0^{2,7}.0^{16,20}]henicosa-1(14),2(7),3,5,15,20-hexaene
Show/Hide
|
C19H21NO2
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0375581
|
10-Methoxy-6-methyl-5,6,7,8,13,14-hexahydrodibenzo[c,g]azecine
Show/Hide
|
C19H23NO
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0375582
|
2-Methyl-1-(2-methylbenzyl)-1,2,3,4-tetrahydroisoquinolin-6-ol
Show/Hide
|
C18H21NO
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0375583
|
6-Methyl-5,6,7,8,13,14-hexahydrodibenzo[c,g]azecin-10-ol
Show/Hide
|
C18H21NO
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0375585
|
3-Methoxy-6,7,9,13b-tetrahydro-5H-isoindolo[1,2-a][2]benzazepine
Show/Hide
|
C18H19NO
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0428950
|
11-Methoxy-6-methyl-5,6,7,8,9,14-hexahydrodibenzo[c,f]azecine
Show/Hide
|
C19H23NO
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0430705
|
6,8,9,13b-tetrahydro-5H-isoquinolino[1,2-a]isoquinolin-3-ol
Show/Hide
|
C17H17NO
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0470276
|
3-(2-Ethyl-4-methoxyphenyl)-2-methyl-1,2,3,4-tetrahydro-isoquinoline
Show/Hide
|
C19H23NO
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0136531
|
2-[[4-(5-chloropyrimidin-2-yl)piperazin-1-yl]methyl]-1-methylbenzimidazole
Show/Hide
|
C17H19ClN6
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0387456
|
2-[1-[(1-methylbenzimidazol-2-yl)methyl]piperidin-4-yl]-1,3-benzothiazole
Show/Hide
|
C21H22N4S
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0387459
|
1-methyl-2-[[4-[5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl]methyl]benzimidazole
Show/Hide
|
C19H20F3N5
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0422141
|
1-methyl-2-((4-(4-(trifluoromethyl)phenyl)piperidin-1-yl)methyl)-1H-benzo[d]imidazole
Show/Hide
|
C21H22F3N3
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0446516
|
2-[[4-(4-chlorophenyl)-1-piperazinyl]methyl]-1-methylbenzimidazole
Show/Hide
|
C19H21ClN4
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0452269
|
1-methyl-2-[[4-[4-(trifluoromethyl)phenyl]piperazin-1-yl]methyl]benzimidazole
Show/Hide
|
C20H21F3N4
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0452272
|
2-[4-[(1-methylbenzimidazol-2-yl)methyl]piperazin-1-yl]-1,3-benzothiazole
Show/Hide
|
C20H21N5S
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0513314
|
1-methyl-2-[[4-[3-(trifluoromethyl)phenyl]piperidin-1-yl]methyl]benzimidazole
Show/Hide
|
C21H22F3N3
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
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CP0372229
|
(4aR,10bR)-4-propyl-9-(2H-tetrazol-5-yl)-2,3,4a,5,6,10b-hexahydrobenzo[h][1,4]benzoxazine
Show/Hide
|
C16H21N5O
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0389482
|
(4aR,10bR)-N-methyl-4-propyl-2,3,4a,5,6,10b-hexahydrobenzo[h][1,4]benzoxazine-9-carboxamide
Show/Hide
|
C17H24N2O2
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0389483
|
methyl (4aR,10bR)-4-propyl-2,3,4a,5,6,10b-hexahydrobenzo[h][1,4]benzoxazine-9-carboxylate
Show/Hide
|
C17H23NO3
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0398421
|
(4aR,10bR)-N-[(4-methoxyphenyl)methyl]-4-propyl-2,3,4a,5,6,10b-hexahydrobenzo[h][1,4]benzoxazine-9-carboxamide
Show/Hide
|
C24H30N2O3
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0417746
|
(4aR,10bR)-N-butyl-4-propyl-2,3,4a,5,6,10b-hexahydrobenzo[h][1,4]benzoxazine-9-carboxamide
Show/Hide
|
C20H30N2O2
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0434836
|
(4aR,10bR)-N,N-dimethyl-4-propyl-2,3,4a,5,6,10b-hexahydrobenzo[h][1,4]benzoxazine-9-carboxamide
Show/Hide
|
C18H26N2O2
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0074771
|
4-[3-[(4-methyl-5-thiophen-3-yl-1,2,4-triazol-3-yl)sulfanyl]propyl]-2-[4-(trifluoromethyl)phenyl]morpholine
Show/Hide
|
C21H23F3N4OS2
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0174644
|
4-[3-[(4-methyl-5-pyridin-3-yl-1,2,4-triazol-3-yl)sulfanyl]propyl]-2-[4-(trifluoromethyl)phenyl]morpholine
Show/Hide
|
C22H24F3N5OS
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0174646
|
4-[3-[(4-methyl-5-pyrazin-2-yl-1,2,4-triazol-3-yl)sulfanyl]propyl]-2-[4-(trifluoromethyl)phenyl]morpholine
Show/Hide
|
C21H23F3N6OS
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0304468
|
4-[4-methyl-5-[3-[2-[4-(trifluoromethyl)phenyl]morpholin-4-yl]propylsulfanyl]-1,2,4-triazol-3-yl]benzamide
Show/Hide
|
C24H26F3N5O2S
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0304469
|
3-[4-methyl-5-[3-[2-[4-(trifluoromethyl)phenyl]morpholin-4-yl]propylsulfanyl]-1,2,4-triazol-3-yl]benzamide
Show/Hide
|
C24H26F3N5O2S
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0304470
|
2-(4-fluorophenyl)-4-[3-[[4-methyl-5-(4-methyl-1,3-oxazol-5-yl)-1,2,4-triazol-3-yl]sulfanyl]propyl]morpholine
Show/Hide
|
C20H24FN5O2S
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0311467
|
4-[3-[[4-methyl-5-[4-(1,3-oxazol-2-yl)phenyl]-1,2,4-triazol-3-yl]sulfanyl]propyl]-2-[4-(trifluoromethyl)phenyl]morpholine
Show/Hide
|
C26H26F3N5O2S
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0324090
|
2-(4-bromophenyl)-4-[3-[[4-methyl-5-(4-methyl-1,3-oxazol-5-yl)-1,2,4-triazol-3-yl]sulfanyl]propyl]morpholine
Show/Hide
|
C20H24BrN5O2S
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0324092
|
4-[3-[[4-methyl-5-[4-(1,2,4-triazol-4-yl)phenyl]-1,2,4-triazol-3-yl]sulfanyl]propyl]-2-[4-(trifluoromethyl)phenyl]morpholine
Show/Hide
|
C25H26F3N7OS
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0364124
|
4-[3-[[4-methyl-5-(1,3-thiazol-2-yl)-1,2,4-triazol-3-yl]sulfanyl]propyl]-2-[4-(trifluoromethyl)phenyl]morpholine
Show/Hide
|
C20H22F3N5OS2
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0364125
|
4-[3-[(4-methyl-5-pyridin-4-yl-1,2,4-triazol-3-yl)sulfanyl]propyl]-2-[4-(trifluoromethyl)phenyl]morpholine
Show/Hide
|
C22H24F3N5OS
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0366924
|
4-[4-[[4-methyl-5-(4-methyl-1,3-oxazol-5-yl)-1,2,4-triazol-3-yl]sulfanyl]butyl]-2-[4-(trifluoromethyl)phenyl]morpholine
Show/Hide
|
C22H26F3N5O2S
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0369179
|
2-[2-fluoro-4-(trifluoromethyl)phenyl]-4-[3-[[4-methyl-5-(4-methyl-1,3-oxazol-5-yl)-1,2,4-triazol-3-yl]sulfanyl]propyl]morpholine
Show/Hide
|
C21H23F4N5O2S
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0395126
|
4-[4-methyl-5-[3-[2-[4-(trifluoromethyl)phenyl]morpholin-4-yl]propylsulfanyl]-1,2,4-triazol-3-yl]benzonitrile
Show/Hide
|
C24H24F3N5OS
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0443256
|
4-[3-[[4-methyl-5-(4-methyl-1,3-oxazol-5-yl)-1,2,4-triazol-3-yl]sulfanyl]propyl]-2-(4-methylphenyl)morpholine
Show/Hide
|
C21H27N5O2S
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0447886
|
4-[4-methyl-5-[3-[2-[4-(trifluoromethyl)phenyl]morpholin-4-yl]propylsulfanyl]-1,2,4-triazol-3-yl]benzenesulfonamide
Show/Hide
|
C23H26F3N5O3S2
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0455295
|
4-[3-[[4-methyl-5-(3-methylimidazol-4-yl)-1,2,4-triazol-3-yl]sulfanyl]propyl]-2-[4-(trifluoromethyl)phenyl]morpholine
Show/Hide
|
C21H25F3N6OS
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0455296
|
5-[4-methyl-5-[3-[2-[4-(trifluoromethyl)phenyl]morpholin-4-yl]propylsulfanyl]-1,2,4-triazol-3-yl]pyridine-3-carboxamide
Show/Hide
|
C23H25F3N6O2S
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0455943
|
4-[3-[[4-methyl-5-(1-methylpyrrol-2-yl)-1,2,4-triazol-3-yl]sulfanyl]propyl]-2-[4-(trifluoromethyl)phenyl]morpholine
Show/Hide
|
C22H26F3N5OS
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0376284
|
(2S)-4-[(3,4-dimethylphenyl)methyl]-2-(phenylsulfanylmethyl)morpholine
Show/Hide
|
C20H25NOS
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0401192
|
(2S)-2-[(6-chloropyridin-2-yl)oxymethyl]-4-[(6-fluoro-1H-indol-3-yl)methyl]morpholine
Show/Hide
|
C19H19ClFN3O2
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0452595
|
(2S)-4-[(4-chlorophenyl)methyl]-2-(phenylsulfanylmethyl)morpholine
Show/Hide
|
C18H20ClNOS
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0399600
|
2-[(6S,7S)-3-(benzenesulfonyl)-6-(methylamino)-6,7-dihydrocyclobuta[e]indol-7-yl]ethanol
Show/Hide
|
C19H20N2O3S
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0466956
|
2-[(6R,7R)-3-(benzenesulfonyl)-7-(methylamino)-6,7-dihydrocyclobuta[e]indol-6-yl]ethanol
Show/Hide
|
C19H20N2O3S
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0389514
|
4-phenyl-N-[4-(propylamino)butyl]benzamide
Show/Hide
|
C20H26N2O
|
1
|
| 1 |
Ki = 11000 nM
|
|
|
|
CP0373496
|
(R)-2-Phenyl-6-(4-phenyl-piperazin-1-ylmethyl)-5,6-dihydro-3H-pyrimidin-4-one
Show/Hide
|
C21H24N4O
|
1
|
| 1 |
Ki = 12000 nM
|
|
|
|
CP0395092
|
(R)-2-Phenyl-5-(4-phenyl-piperazin-1-yl)-4,5,6,7-tetrahydro-1H-[1,3]diazepine
Show/Hide
|
C21H26N4
|
1
|
| 1 |
Ki = 12000 nM
|
|
|
|
CP0295827
|
5-Dipropylamino-4,5,6,7-tetrahydro-pyrazolo[1,5-a]pyridine-3-carbaldehyde
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C14H23N3O
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1
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| 1 |
Ki = 12000 nM
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CP0297053
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5-Propylamino-4,5,6,7-tetrahydro-pyrazolo[1,5-a]pyridine-3-carboxylic acid methyl ester
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C12H19N3O2
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1
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| 1 |
Ki = 12000 nM
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CP0911242
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((R)-3-Dimethylaminomethyl-5,6,7,8-tetrahydro-indolizin-7-yl)-dipropyl-amine
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C17H31N3
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1
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| 1 |
Ki = 12022.64 nM
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CP0376507
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2-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-1H-indole-5-carbonitrile
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C20H19ClN4
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1
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| 1 |
Ki = 13000 nM
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CP0374994
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(S)-2-Phenyl-4-(4-phenyl-piperazin-1-ylmethyl)-1,4,5,6-tetrahydro-pyrimidine
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C21H26N4
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1
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| 1 |
Ki = 13000 nM
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CP0380469
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(R)-2-Phenyl-4-(4-phenyl-piperazin-1-ylmethyl)-1,4,5,6-tetrahydro-pyrimidine
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C21H26N4
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1
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| 1 |
Ki = 13000 nM
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CP0167457
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3-{[4-(4-Methoxyphenyl)piperazin-1-yl]methyl}-2,7-dimethylimidazo[1,2-c]pyrimidine
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C20H25N5O
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1
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| 1 |
Ki = 13000 nM
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CP0341419
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5,6-dimethoxy-11-methyl-11-aza-tricyclo[13.4.0.0.3,8]nonadeca-1(15),3(8),4,6,16,18-hexaene
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C21H27NO2
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1
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| 1 |
Ki = 14830 nM
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CP0464939
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1-Benzyl-4-pyrrol-1-yl-piperidine
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C16H20N2
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1
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| 1 |
Ki = 15000 nM
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CP0451864
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2-((4-(4-fluorophenyl)piperazin-1-yl)methyl)-1H-indole-5-carbonitrile
Show/Hide
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C20H19FN4
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1
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| 1 |
Ki = 15000 nM
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CP0428039
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2-[[4-[4-(2-fluoroethoxy)phenyl]piperazin-1-yl]methyl]pyrazolo[1,5-a]pyridine
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C20H23FN4O
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1
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| 1 |
Ki = 15000 nM
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CP0380592
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3-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-7-ethynyl-2-methyl-pyrazolo[1,5-a]pyridine
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C21H21ClN4
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1
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| 1 |
Ki = 17000 nM
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CP0251113
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5-Dipropylamino-4,5,6,7-tetrahydro-pyrazolo[1,5-a]pyridine-3-carboxylic acid methyl ester
Show/Hide
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C15H25N3O2
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1
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| 1 |
Ki = 17000 nM
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CP0391219
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1-[[1-[4-(2-fluoroethoxy)phenyl]triazol-4-yl]methyl]-4-(2-methoxyphenyl)piperazine
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C22H26FN5O2
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1
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| 1 |
Ki = 17000 nM
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CP0434139
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(2R,3S,4S,5R,6R)-5-fluoro-2-(hydroxymethyl)-6-[4-[[4-(2-methoxyphenyl)piperazin-1-yl]methyl]triazol-1-yl]oxane-3,4-diol
Show/Hide
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C20H28FN5O5
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1
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| 1 |
Ki = 17000 nM
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CP0457577
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N-[2-[4-(1H-indol-2-ylmethyl)piperazin-1-yl]ethyl]-4-methoxyaniline
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C22H28N4O
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1
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| 1 |
Ki = 18000 nM
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CP0402903
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2-[4-(3,4-Dichloro-phenyl)-piperazin-1-ylmethyl]-1H-indole-5-carbonitrile
Show/Hide
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C20H18Cl2N4
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1
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| 1 |
Ki = 20000 nM
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CP0432261
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(S)-2-Phenyl-6-(4-phenyl-piperazin-1-ylmethyl)-5,6-dihydro-3H-pyrimidin-4-one
Show/Hide
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C21H24N4O
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1
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| 1 |
Ki = 20000 nM
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CP0449675
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3-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-2-methyl-pyrazolo[1,5-a]pyridine-7-carbonitrile
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C20H20ClN5
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1
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| 1 |
Ki = 21000 nM
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CP0276689
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3-{[4-(4-Fluorophenyl)piperazin-1-yl]methyl}-2,5,7-trimethylimidazo[1,2-c]pyrimidine
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C20H24FN5
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1
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| 1 |
Ki = 22000 nM
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CP0277602
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2-methoxy-7-methyl-6,7,8,9,10,15-hexahydro-5H-dibenzo[d,g]azacycloundecene
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C20H25NO
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1
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| 1 |
Ki = 23903 nM
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CP0461939
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(2S,3S,4S,5R,6R)-2-(fluoromethyl)-6-[4-[[4-(2-methoxyphenyl)piperazin-1-yl]methyl]triazol-1-yl]oxane-3,4,5-triol
Show/Hide
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C20H28FN5O5
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1
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| 1 |
Ki = 25000 nM
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CP0405288
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3-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-pyrazolo[1,5-a]pyridine-7-carbonitrile
Show/Hide
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C19H18ClN5
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1
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| 1 |
Ki = 26000 nM
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CP0392953
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2-{5-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-1H-pyrrol-2-ylmethylene}-malononitrile
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C19H18ClN5
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1
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| 1 |
Ki = 31000 nM
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CP0401045
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1-(1-Benzyl-piperidin-4-yl)-1H-pyrrole-3-carbaldehyde
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C17H20N2O
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1
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| 1 |
Ki = 31000 nM
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CP0377770
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2-[4-(3,4-Dichloro-phenyl)-piperazin-1-ylmethyl]-1H-indole-6-carbonitrile
Show/Hide
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C20H18Cl2N4
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1
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| 1 |
Ki = 33000 nM
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CP0445951
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2-[4-(4-fluorophenyl)piperazin-1-ylmethyl]imidazo[1,2-a]pyrazine
Show/Hide
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C17H18FN5
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1
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| 1 |
Ki = 42000 nM
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CP0456414
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2-[4-(4-fluorophenyl)piperazin-1-ylmethyl]imidazo[1,2-a]pyrimidine
Show/Hide
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C17H18FN5
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1
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| 1 |
Ki = 60000 nM
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CP0276665
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3-{[4-(2-Methoxyphenyl)piperazin-1-yl]methyl}-2,7-dimethylimidazo[1,2-c]pyrimidine
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C20H25N5O
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1
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| 1 |
Ki = 67000 nM
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CP0405399
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[3-[[4-(4-chlorophenyl)piperazin-1-yl]methyl]pyrazolo[1,5-a]pyridin-4-yl]methanol
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C19H21ClN4O
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1
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| 1 |
Ki > 100000 nM
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CP0380149
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N-[2-fluoro-5-[2-(thiophen-2-ylmethylamino)ethoxy]phenyl]methanesulfonamide
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C14H17FN2O3S2
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1
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| 1 |
Ki > 400 nM
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CP0399395
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2-(4-Benzyl-piperazin-1-yl)-phenol
Show/Hide
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C17H20N2O
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1
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| 1 |
Ki > 400 nM
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CP0401301
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4-(4-Benzyl-piperazin-1-yl)-phenol
Show/Hide
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C17H20N2O
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1
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| 1 |
Ki > 400 nM
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CP0439814
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1-Benzyl-4-phenyl-piperazine
Show/Hide
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C17H20N2
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1
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| 1 |
Ki > 400 nM
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CP0498116
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Benzyl-(2-phenoxy-ethyl)-amine
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C15H17NO
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1
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| 1 |
Ki > 400 nM
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CP0360497
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5-[5-[3-[(1R,5S)-1-(4-bromophenyl)-3-azabicyclo[3.1.0]hexan-3-yl]propylsulfanyl]-4-methyl-1,2,4-triazol-3-yl]-2-methylquinoline
Show/Hide
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C27H28BrN5S
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1
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| 1 |
Ki > 501.19 nM
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CP0870009
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(2H-Benzo[1,4]oxazin-3-yl)-{3-[4-(2-methoxy-phenyl)-piperazin-1-yl]-propyl}-amine; compound with but-2-enedioic acid
Show/Hide
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C26H32N4O6
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1
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| 1 |
Ki > 1000 nM
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CP0439817
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5-(2-Benzylamino-ethoxy)-2-chloro-phenylamine
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C15H17ClN2O
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1
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| 1 |
Ki > 1000 nM
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CP0082421
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5-chloro-3-methyl-N-(2-methyl-4-piperazin-1-ylquinolin-6-yl)-1-benzothiophene-2-sulfonamide
Show/Hide
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C23H23ClN4O2S2
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1
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| 1 |
Ki < 1000 nM
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CP0426889
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N-[4-(2,5-diazatetracyclo[13.4.0.02,7.08,13]nonadeca-1(19),8,10,12,15,17-hexaen-5-yl)butyl]naphthalene-2-carboxamide
Show/Hide
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C32H33N3O
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1
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| 1 |
Ki > 1000 nM
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CP0426892
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2-[4-[4-(N-benzylanilino)piperidin-1-yl]butyl]isoindole-1,3-dione
Show/Hide
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C30H33N3O2
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1
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| 1 |
Ki > 1000 nM
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CP0426893
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N-[4-(2,5-diazatetracyclo[13.4.0.02,7.08,13]nonadeca-1(19),8,10,12,15,17-hexaen-5-yl)butyl]-1-benzothiophene-2-carboxamide
Show/Hide
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C30H31N3OS
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1
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| 1 |
Ki > 1000 nM
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CP0427967
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N-[4-(2,5-diazatetracyclo[13.4.0.02,7.08,13]nonadeca-1(19),8,10,12,15,17-hexaen-5-yl)butyl]cyclohexanecarboxamide
Show/Hide
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C28H37N3O
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1
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| 1 |
Ki > 1000 nM
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CP0445344
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2-(4-(4-(2-methoxyphenylamino)piperidin-1-yl)butyl)isoindoline-1,3-dione
Show/Hide
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C24H29N3O3
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1
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| 1 |
Ki > 1000 nM
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CP0460993
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N-[4-[4-(N-benzoyl-2-methoxyanilino)piperidin-1-yl]butyl]naphthalene-2-carboxamide
Show/Hide
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C34H37N3O3
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1
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| 1 |
Ki > 1000 nM
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CP0541733
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N-[4-[4-(2-methoxy-N-propanoylanilino)piperidin-1-yl]butyl]naphthalene-2-carboxamide
Show/Hide
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C30H37N3O3
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1
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| 1 |
Ki > 1000 nM
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CP0173778
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5-chloro-3-methyl-N-(4-piperazin-1-ylquinolin-6-yl)-1-benzothiophene-2-sulfonamide
Show/Hide
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C22H21ClN4O2S2
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1
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| 1 |
Ki < 1584.89 nM
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CP0208303
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5-chloro-2-methyl-N-(4-piperazin-1-ylquinolin-6-yl)-1-benzothiophene-3-sulfonamide
Show/Hide
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C22H21ClN4O2S2
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1
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| 1 |
Ki < 1584.89 nM
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CP0343547
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5-chloro-3-methyl-N-[4-[(3S)-3-methylpiperazin-1-yl]quinolin-6-yl]-1-benzothiophene-2-sulfonamide
Show/Hide
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C23H23ClN4O2S2
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1
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| 1 |
Ki < 1995.26 nM
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CP0139431
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(7R,9aS)-7-(4-Fluoro-phenoxymethyl)-2-(5-fluoro-pyrimidin-2-yl)-octahydro-pyrido[1,2-a]pyrazine
Show/Hide
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C19H22F2N4O
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1
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| 1 |
Ki > 2000 nM
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CP0420769
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4-[3-[4-[1-[(E)-4-[2-[4-(3-morpholin-4-ylpropoxy)phenyl]benzimidazol-1-yl]but-2-enyl]benzimidazol-2-yl]phenoxy]propyl]morpholine
Show/Hide
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C44H50N6O4
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1
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| 1 |
Ki > 2040 nM
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CP0378038
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N-[4-[4-(5-methoxy-1,2-benzoxazol-3-yl)piperazin-1-yl]butyl]-2-oxochromene-3-carboxamide
Show/Hide
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C26H28N4O5
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1
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| 1 |
Ki > 2700 nM
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CP0374745
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3-{2-[4-(4-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-2-methyl-2,3-dihydro-isoindol-1-one
Show/Hide
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C22H27N3O2
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1
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| 1 |
Ki > 3000 nM
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CP0406477
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3-{2-[4-(4-Methyl-pyridin-2-yl)-piperazin-1-yl]-ethyl}-2,3-dihydro-isoindol-1-one
Show/Hide
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C20H24N4O
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1
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| 1 |
Ki > 3000 nM
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CP0422364
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3-{2-[4-(4-Chloro-phenyl)-piperazin-1-yl]-ethyl}-2-methyl-2,3-dihydro-isoindol-1-one
Show/Hide
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C21H24ClN3O
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1
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| 1 |
Ki > 3000 nM
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CP0438498
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3-{2-[4-(4-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-2,3-dihydro-isoindol-1-one
Show/Hide
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C21H25N3O2
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1
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| 1 |
Ki > 3000 nM
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CP0438506
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3-{2-[4-(3,4-Dimethyl-phenyl)-piperidin-1-yl]-ethyl}-2,3-dihydro-isoindol-1-one
Show/Hide
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C23H28N2O
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1
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| 1 |
Ki > 3000 nM
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CP0454655
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3-[2-(4-Naphthalen-2-yl-piperazin-1-yl)-ethyl]-2,3-dihydro-isoindol-1-one
Show/Hide
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C24H25N3O
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1
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| 1 |
Ki > 3000 nM
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CP0461461
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3-[2-(4-p-Tolyl-piperazin-1-yl)-ethyl]-2,3-dihydro-isoindol-1-one
Show/Hide
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C21H25N3O
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1
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| 1 |
Ki > 3000 nM
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CP0465331
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3-{2-[4-(4-Chloro-phenyl)-piperazin-1-yl]-ethyl}-2,3-dihydro-isoindol-1-one
Show/Hide
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C20H22ClN3O
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1
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| 1 |
Ki > 3000 nM
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CP0468089
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3-{2-[4-(4,5-Dimethyl-thiazol-2-yl)-piperazin-1-yl]-ethyl}-2,3-dihydro-isoindol-1-one
Show/Hide
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C19H24N4OS
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1
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| 1 |
Ki > 3000 nM
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CP0468090
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3-{2-[4-(3,4-Dimethyl-phenyl)-piperazin-1-yl]-ethyl}-2-methyl-2,3-dihydro-isoindol-1-one
Show/Hide
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C23H29N3O
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1
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| 1 |
Ki > 3000 nM
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CP0376592
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6-[4-(4-Methoxy-phenyl)-piperazin-1-ylmethyl]-4H-benzo[1,4]oxazin-3-one
Show/Hide
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C20H23N3O3
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1
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| 1 |
Ki > 3030 nM
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CP0405997
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6-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-4H-benzo[1,4]oxazin-3-one
Show/Hide
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C19H20ClN3O2
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1
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| 1 |
Ki > 3030 nM
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CP0415085
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6-(4-p-Tolyl-piperidin-1-ylmethyl)-4H-benzo[1,4]oxazin-3-one
Show/Hide
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C21H24N2O2
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1
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| 1 |
Ki > 3030 nM
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CP0430181
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6-[4-(3,4-Dimethyl-phenyl)-piperidin-1-ylmethyl]-4H-benzo[1,4]oxazin-3-one
Show/Hide
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C22H26N2O2
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1
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| 1 |
Ki > 3030 nM
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CP0480432
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6-[4-(4-Methoxy-phenyl)-piperidin-1-ylmethyl]-4H-benzo[1,4]oxazin-3-one
Show/Hide
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C21H24N2O3
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1
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| 1 |
Ki > 3030 nM
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CP0339112
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4-phenyl-N-(4-piperazin-1-ylquinolin-6-yl)benzenesulfonamide
Show/Hide
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C25H24N4O2S
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1
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| 1 |
Ki < 3162.28 nM
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CP0405355
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3-Piperidin-1-ylmethyl-1H-indole
Show/Hide
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C14H18N2
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1
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| 1 |
Ki > 3700 nM
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CP0306083
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5-chloro-3-methyl-N-[4-(4-methylpiperazin-1-yl)quinolin-6-yl]-1-benzothiophene-2-sulfonamide
Show/Hide
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C23H23ClN4O2S2
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1
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| 1 |
Ki < 3981.07 nM
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CP0169831
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4-[5-(4-Chloro-phenyl)-1H-pyrazol-3-yl]-1-phenethyl-piperidine
Show/Hide
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C22H24ClN3
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1
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| 1 |
Ki > 4000 nM
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CP0915334
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(2H-Benzo[1,4]oxazin-3-yl)-[4-(4-phenyl-piperazin-1-yl)-butyl]-amine; compound with but-2-enedioic acid
Show/Hide
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C26H32N4O5
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1
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| 1 |
Ki > 4000 nM
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CP0237813
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(5-Dipropylamino-4,5,6,7-tetrahydro-pyrazolo[1,5-a]pyridin-3-yl)-methanol
Show/Hide
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C14H25N3O
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1
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| 1 |
Ki > 4000 nM
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CP0436601
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2-[1-(4-Chloro-benzyl)-1,2,3,6-tetrahydro-pyridin-4-yl]-benzothiazole
Show/Hide
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C19H17ClN2S
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1
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| 1 |
Ki > 4400 nM
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CP0161762
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3-[4-(4-Iodo-phenyl)-piperazin-1-ylmethyl]-1H-pyrrolo[2,3-b]pyridine
Show/Hide
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C18H19IN4
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1
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| 1 |
Ki > 4500 nM
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CP0464222
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5-Chloro-2-[1-(4-chloro-benzyl)-1,2,3,6-tetrahydro-pyridin-4-yl]-benzooxazole
Show/Hide
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C19H16Cl2N2O
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1
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| 1 |
Ki > 4500 nM
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CP0306958
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(3aR,9bS) 3-Propyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indol-9-ol
Show/Hide
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C15H21NO
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1
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| 1 |
Ki > 4762 nM
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CP0378555
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4-(2-Benzylamino-ethoxy)-phenol
Show/Hide
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C15H17NO2
|
1
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| 1 |
Ki > 5000 nM
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CP0441639
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N-[5-[2-(benzylamino)ethoxy]-2-fluorophenyl]methanesulfonamide
Show/Hide
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C16H19FN2O3S
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1
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| 1 |
Ki > 5000 nM
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CP0081712
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4-tert-butyl-N-(4-piperazin-1-ylquinolin-6-yl)benzenesulfonamide
Show/Hide
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C23H28N4O2S
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1
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| 1 |
Ki < 5011.87 nM
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CP0536028
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4-(2-Phenyl-3H-imidazol-4-ylmethyl)-3,4,5,6-tetrahydro-2H-[1,2']bipyrazinyl
Show/Hide
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C18H20N6
|
1
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| 1 |
Ki > 6665 nM
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CP0040814
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[4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl]-(furan-2-yl)methanone
Show/Hide
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C19H21N5O4
|
1
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| 1 |
Ki > 7100 nM
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CP0320413
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3-(2-{4-[1-(4-Fluoro-phenyl)-5-(1-methyl-1H-[1,2,4]triazol-3-yl)-1H-indol-3-yl]-piperidin-1-yl}-ethyl)-1-methyl-pyrrolidin-2-one
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C29H33FN6O
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1
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| 1 |
Ki > 7100 nM
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CP0894622
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(2H-Benzo[1,4]oxazin-3-yl)-[4-(4-pyrimidin-2-yl-piperazin-1-yl)-butyl]-amine; compound with but-2-enedioic acid
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C24H30N6O5
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1
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| 1 |
Ki > 7900 nM
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CP0895614
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(2H-Benzo[1,4]oxazin-3-yl)-[3-(4-pyridin-2-yl-piperazin-1-yl)-propyl]-amine; compound with but-2-enedioic acid
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C24H29N5O5
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1
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| 1 |
Ki > 7900 nM
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CP0896993
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(2H-Benzo[1,4]oxazin-3-yl)-[3-(4-pyrimidin-2-yl-piperazin-1-yl)-propyl]-amine; compound with but-2-enedioic acid
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C23H28N6O5
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1
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| 1 |
Ki > 7900 nM
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CP0099176
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CAS_188942
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C18H20N6
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1
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| 1 |
Ki > 8000 nM
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CP0409703
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4-[4-(2-Phenyl-3H-imidazol-4-ylmethyl)-piperazin-1-yl]-pyrimidine
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C18H20N6
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1
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| 1 |
Ki > 8000 nM
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CP0480448
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1-(2-Phenyl-3H-imidazol-4-ylmethyl)-4-pyridin-4-yl-piperazine
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C19H21N5
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1
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| 1 |
Ki > 8000 nM
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CP0381460
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N-[4-[4-(1H-benzimidazol-2-yl)piperazin-1-yl]butyl]-7-methoxy-1-benzofuran-2-carboxamide
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C25H29N5O3
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1
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| 1 |
Ki > 8500 nM
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CP0391643
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7-methoxy-N-[4-[4-(5-methoxy-1,3-benzoxazol-2-yl)piperazin-1-yl]butyl]-1-benzofuran-2-carboxamide
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C26H30N4O5
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1
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| 1 |
Ki > 8500 nM
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CP0018076
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5-Methyl-3,5-dihydro-2H-pyrrolo[2,3-f]indole-1-carboxylic acid pyridin-3-ylamide
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C17H16N4O
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1
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| 1 |
Ki < 10000 nM
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CP0392916
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(4aR,11bS)-4-propyl-2,3,4a,5,6,8,9,11b-octahydro-[1]benzofuro[5,6-h][1,4]benzoxazine
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C17H23NO2
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1
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| 1 |
Ki < 10000 nM
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CP0402197
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(4aR,11bR)-4-benzyl-2,3,4a,5,6,8,9,11b-octahydro-[1]benzofuro[5,6-h][1,4]benzoxazine
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C21H23NO2
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1
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| 1 |
Ki < 10000 nM
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CP0431294
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(4aR,11bR)-4-(2-phenylethyl)-2,3,4a,5,6,8,9,11b-octahydro-[1]benzofuro[5,6-h][1,4]benzoxazine
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C22H25NO2
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1
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| 1 |
Ki < 10000 nM
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CP0457191
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(2S,7R)-6-propyl-3,9,15-trioxa-6-azatetracyclo[8.7.0.02,7.012,16]heptadeca-1(10),11,16-triene
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C16H21NO3
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1
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| 1 |
Ki < 10000 nM
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CP0170807
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5-chloro-3-ethyl-N-(4-piperazin-1-ylquinolin-6-yl)-1-benzothiophene-2-sulfonamide
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C23H23ClN4O2S2
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1
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| 1 |
Ki < 10000 nM
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CP0040453
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CAS_3277600
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C14H14N4OS
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1
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| 1 |
Ki < 31622.78 nM
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