General Information of the Compound
Compound ID
CP0338077
Compound Name
1-(3-methoxyphenyl)-3-[2-(4-propan-2-ylpiperazin-1-yl)ethyl]imidazolidin-2-one
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Structure
Formula
C19H30N4O2
Molecular Weight
346.475
Canonical SMILES
COc1cccc(c1)N1CCN(CCN2CCN(CC2)C(C)C)C1=O
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InChI
InChI=1S/C19H30N4O2/c1-16(2)21-10-7-20(8-11-21)9-12-22-13-14-23(19(22)24)17-5-4-6-18(15-17)25-3/h4-6,15-16H,7-14H2,1-3H3
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InChIKey
RBSYHARPLIHIDB-UHFFFAOYSA-N
Physicochemical Property
logP
1.9632
Rotatable Bonds
6
Heavy Atom Count
25
Polar Areas
39.26
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
4
Complexity
25

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 45272437
ChEMBL ID
CHEMBL550358
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01005, D(2) dopamine receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 2511.89 nM
   TI
   LI
   LO
   TS
Protein ID: PT00943, D(3) dopamine receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 158.49 nM
   TI
   LI
   LO
   TS