General Information of the Compound
Compound ID
CP0460993
Compound Name
N-[4-[4-(N-benzoyl-2-methoxyanilino)piperidin-1-yl]butyl]naphthalene-2-carboxamide
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Structure
Formula
C34H37N3O3
Molecular Weight
535.688
Canonical SMILES
COc1ccccc1N(C1CCN(CCCCNC(=O)c2ccc3ccccc3c2)CC1)C(=O)c1ccccc1
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InChI
InChI=1S/C34H37N3O3/c1-40-32-16-8-7-15-31(32)37(34(39)27-12-3-2-4-13-27)30-19-23-36(24-20-30)22-10-9-21-35-33(38)29-18-17-26-11-5-6-14-28(26)25-29/h2-8,11-18,25,30H,9-10,19-24H2,1H3,(H,35,38)
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InChIKey
YJRKUTHRZOUCHT-UHFFFAOYSA-N
Physicochemical Property
logP
6.1698
Rotatable Bonds
10
Heavy Atom Count
40
Polar Areas
61.88
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
4
Complexity
40

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 44436769
ChEMBL ID
CHEMBL241018
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01005, D(2) dopamine receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki = 4620 nM
   TI
   LI
   LO
   TS
Protein ID: PT00943, D(3) dopamine receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki > 1000 nM
   TI
   LI
   LO
   TS