General Information of the Compound
Compound ID
CP0466321
Compound Name
1-[(6R)-6-(dipropylamino)-1-methoxy-5,6,7,8-tetrahydronaphthalen-2-yl]-2-(4-methoxyphenyl)ethanol
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Structure
Formula
C26H37NO3
Molecular Weight
411.586
Canonical SMILES
CCCN(CCC)[C@@H]1CCc2c(C1)ccc(C(O)Cc1ccc(OC)cc1)c2OC
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InChI
InChI=1S/C26H37NO3/c1-5-15-27(16-6-2)21-10-14-23-20(18-21)9-13-24(26(23)30-4)25(28)17-19-7-11-22(29-3)12-8-19/h7-9,11-13,21,25,28H,5-6,10,14-18H2,1-4H3/t21-,25?/m1/s1
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InChIKey
XOWASPOXQFROJP-JGKWMGOWSA-N
Physicochemical Property
logP
4.9592
Rotatable Bonds
10
Heavy Atom Count
30
Polar Areas
41.93
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
4
Complexity
30

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 44353425
ChEMBL ID
CHEMBL133018
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00943, D(3) dopamine receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 50.12 nM
   TI
   LI
   LO
   TS