General Information of the Compound
Compound ID
CP0439809
Compound Name
(E)-N-[4-(2,5-diazatetracyclo[13.4.0.02,7.08,13]nonadeca-1(19),8,10,12,15,17-hexaen-5-yl)butyl]-3-phenylprop-2-enamide
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Structure
Formula
C30H33N3O
Molecular Weight
451.614
Canonical SMILES
O=C(NCCCCN1CCN2C(C1)c1ccccc1Cc1ccccc21)\C=C\c1ccccc1
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InChI
InChI=1S/C30H33N3O/c34-30(17-16-24-10-2-1-3-11-24)31-18-8-9-19-32-20-21-33-28-15-7-5-13-26(28)22-25-12-4-6-14-27(25)29(33)23-32/h1-7,10-17,29H,8-9,18-23H2,(H,31,34)/b17-16+
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InChIKey
NQOBWBPQVJMZSQ-WUKNDPDISA-N
Physicochemical Property
logP
5.0639
Rotatable Bonds
7
Heavy Atom Count
34
Polar Areas
35.58
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
3
Complexity
34

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 44436746
ChEMBL ID
CHEMBL239065
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01005, D(2) dopamine receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki = 429 nM
   TI
   LI
   LO
   TS
Protein ID: PT00943, D(3) dopamine receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 50.2 nM
   TI
   LI
   LO
   TS