General Information of the Compound
Compound ID
CP0515940
Compound Name
N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]-4-morpholin-4-ylbenzamide
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Structure
Formula
C26H36N4O3
Molecular Weight
452.599
Canonical SMILES
COc1ccccc1N1CCN(CCCCNC(=O)c2ccc(cc2)N2CCOCC2)CC1
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InChI
InChI=1S/C26H36N4O3/c1-32-25-7-3-2-6-24(25)30-16-14-28(15-17-30)13-5-4-12-27-26(31)22-8-10-23(11-9-22)29-18-20-33-21-19-29/h2-3,6-11H,4-5,12-21H2,1H3,(H,27,31)
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InChIKey
BQJVXLMFXRFJSZ-UHFFFAOYSA-N
Physicochemical Property
logP
2.864
Rotatable Bonds
9
Heavy Atom Count
33
Polar Areas
57.28
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
6
Complexity
33

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 11577696
SID: 16795353
ChEMBL ID
CHEMBL203302
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01005, D(2) dopamine receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000049 C6 Rattus norvegicus (Rat)  1
1
Ki = 141 nM
   TI
   LI
   LO
   TS
Protein ID: PT00943, D(3) dopamine receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 23.9 nM
   TI
   LI
   LO
   TS