General Information of the Cell Line
Cell Line ID
CL000049
Cell Line Name
C6
Synonyms
C-6
C 6
RGC-6
RGC6
RGc6
Category
Cancer cell line
Organism
Rattus norvegicus (Rat)
Cellosaurus ID
CVCL_0194
Tissue Information
Brain
Disease
Rat malignant glioma (NCIt: C64069)
Map of Molecular Bioactivity Related to the Cell Line
Map of Molecular Bioactivity Related to the Cell Line

Cell Line
Protein
Compound

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Cell Line
Protein ID: PT01307, 5-hydroxytryptamine receptor 4
 Protein Info 
Compound ID Compound Name Compound Formula
CP0908258
 Compound Info 
2-[4-({6-[6-Amino-1,3-dioxo-1H-benzo[de]isoquinolin-2(3H)-yl]hexanoyl}amino)piperidino]ethyl 4-Amino-5-chloro-2-methoxybenzoate
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C32H36ClN5O6
  2
1
EC50 = 4 nM
 Bioactivity Info 
   TI
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2
Ki = 111 nM
 Bioactivity Info 
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CP0481292
 Compound Info 
ML10302 scaffold, 14
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C50H72Cl2N8O8
  2
1
EC50 = 9 nM
 Bioactivity Info 
   TI
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2
Ki = 14 nM
 Bioactivity Info 
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CP0001238
 Compound Info 
14C-5-hydroxy tryptamine creatinine disulfate
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C10H12N2O
  2
1
EC50 = 12 nM
 Bioactivity Info 
   TI
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2
Ki = 1049 nM
 Bioactivity Info 
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CP0481291
 Compound Info 
ML10302 scaffold, 9{a;q}
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C23H27Cl2N3O4
  2
1
EC50 = 18 nM
 Bioactivity Info 
   TI
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2
Ki = 5 nM
 Bioactivity Info 
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CP0290551
 Compound Info 
2-Piperidinoethyl 4-amino-5-chloro-2-methoxybenzoate
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C15H21ClN2O3
  4
1
EC50 = 51 nM
 Bioactivity Info 
   TI
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2
Ki = 1 nM
 Bioactivity Info 
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3
Ki = 5 nM
 Bioactivity Info 
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4
Ki = 5.6 nM
 Bioactivity Info 
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CP0435095
 Compound Info 
ML10302 scaffold, 9{b;w}
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C27H37ClN4O6S
  2
1
EC50 = 68 nM
 Bioactivity Info 
   TI
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2
Ki = 2 nM
 Bioactivity Info 
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CP0123097
 Compound Info 
3H-GR113808
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C19H27N3O4S
  2
1
Ki = 0.1 nM
 Bioactivity Info 
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2
Ki = 0.5 nM
 Bioactivity Info 
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CP0373139
 Compound Info 
4-Amino-5-chloro-2-methoxy-benzoic acid 2-(4-pyrimidin-2-yl-piperazin-1-yl)-ethyl ester
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C18H22ClN5O3
  1
1
Ki = 1 nM
 Bioactivity Info 
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CP0404014
 Compound Info 
4-Amino-5-chloro-2-methoxy-benzoic acid 2-(4-pyridazin-3-yl-piperazin-1-yl)-ethyl ester
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C18H22ClN5O3
  1
1
Ki = 1.4 nM
 Bioactivity Info 
   TI
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CP0482880
 Compound Info 
4-Amino-5-chloro-2-methoxy-benzoic acid 2-(2,3,5,6-tetrahydro-[1,2']bipyrazinyl-4-yl)-ethyl ester
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C18H22ClN5O3
  1
1
Ki = 1.4 nM
 Bioactivity Info 
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CP0397652
 Compound Info 
4-Amino-5-chloro-2-methoxy-benzoic acid 2-(4-pyridin-2-yl-piperazin-1-yl)-ethyl ester
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C19H23ClN4O3
  1
1
Ki = 1.5 nM
 Bioactivity Info 
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CP0449044
 Compound Info 
4-Amino-5-chloro-2-methoxy-benzoic acid 2-[4-(6-chloro-pyridazin-3-yl)-piperazin-1-yl]-ethyl ester
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C18H21Cl2N5O3
  1
1
Ki = 2 nM
 Bioactivity Info 
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CP0265345
 Compound Info 
4-Amino-5-chloro-2-methoxy-benzoic acid 2-[4-(3-methoxy-phenyl)-piperazin-1-yl]-ethyl ester
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C21H26ClN3O4
  1
1
Ki = 3 nM
 Bioactivity Info 
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CP0457326
 Compound Info 
4-Amino-5-chloro-2-methoxy-benzoic acid 2-(4-pyridin-4-yl-piperazin-1-yl)-ethyl ester
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C19H23ClN4O3
  1
1
Ki = 3.5 nM
 Bioactivity Info 
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CP0448448
 Compound Info 
4-Amino-5-chloro-2-methoxy-benzoic acid 2-{4-[(5-dimethylamino-naphthalene-1-sulfonylamino)-methyl]-piperidin-1-yl}-ethyl ester
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C28H35ClN4O5S
  1
1
Ki = 7 nM
 Bioactivity Info 
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CP0463026
 Compound Info 
2-[4-({5-[(1-{2-[(4-amino-5-chloro-2-methoxyphenyl)carbonyloxy]ethyl}piperidin-4-yl)carbamoyl]pentyl}carbamoyl)piperidin-1-yl]ethyl 4-amino-5-chloro-2-methoxybenzoate
   Show/Hide
C37H52Cl2N6O8
  1
1
Ki = 7 nM
 Bioactivity Info 
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CP0374637
 Compound Info 
4-Amino-5-chloro-2-methoxy-benzoic acid 2-{4-[(7-nitro-benzo[1,2,5]oxadiazol-4-ylamino)-methyl]-piperidin-1-yl}-ethyl ester
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C22H25ClN6O6
  1
1
Ki = 7.5 nM
 Bioactivity Info 
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CP0876620
 Compound Info 
2-(4-{4-[N-(3-{3-[3-(N-{3-[(1-{2-[(4-amino-2-methoxyphenyl)carbonyloxy]ethyl}piperidin-4-yl)carbamoyl]propyl}-2,2-dimethylpropanamido)prop-1-yn-1-yl]phenyl}prop-2-yn-1-yl)-2,2-dimethylpropanamido]butanamido}piperidin-1-yl)ethyl 4-amino-5-chloro-2-methoxybenzoate
   Show/Hide
C60H80Cl2N8O12
  1
1
Ki = 8 nM
 Bioactivity Info 
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CP0184481
 Compound Info 
1-[2-(4-amino-5-chloro-2-methoxyphenylcarbonyloxy)ethyl]-4-{2-[10-(2-{1-[2-(4-amino-5-chloro-2-methoxyphenylcarbonyloxy)ethyl]hexahydro-4-pyridinyl}ethylcarbamoyl)decylcarboxamido]ethyl}hexahydropyridine
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C46H70Cl2N6O8
  1
1
Ki = 9 nM
 Bioactivity Info 
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CP0432877
 Compound Info 
4-Amino-5-chloro-2-methoxy-benzoic acid 2-(4-pyrimidin-5-yl-piperazin-1-yl)-ethyl ester
   Show/Hide
C18H22ClN5O3
  1
1
Ki = 9.2 nM
 Bioactivity Info 
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CP0461031
 Compound Info 
4-Amino-5-chloro-2-methoxy-benzoic acid 2-[4-(2-chloro-pyrimidin-5-yl)-piperazin-1-yl]-ethyl ester
   Show/Hide
C18H21Cl2N5O3
  1
1
Ki = 9.8 nM
 Bioactivity Info 
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CP0860113
 Compound Info 
4-Amino-5-chloro-2-methoxy-benzoic acid 3-(4-cyclohexa-2,4-dienyl-piperazin-1-yl)-propyl ester
   Show/Hide
C21H26ClN3O3
  1
1
Ki = 11.5 nM
 Bioactivity Info 
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CP0913714
 Compound Info 
2-(4-{4-[N-(3-{4-[3-(N-{3-[(1-{2-[(4-amino-5-chloro-2-methoxyphenyl)carbonyloxy]ethyl}piperidin-4-yl)carbamoyl]propyl}-2,2-dimethylpropanamido)propyl]phenyl}propyl)-2,2-dimethylpropanamido]butanamido}piperidin-1-yl)ethyl 4-amino-5-chloro-2-methoxybenzoate
   Show/Hide
C60H88Cl2N8O12
  1
1
Ki = 12 nM
 Bioactivity Info 
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CP0527048
 Compound Info 
ML10302 scaffold, 19
   Show/Hide
C28H39ClN4O4
  1
1
Ki = 12 nM
 Bioactivity Info 
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CP0448968
 Compound Info 
4-Amino-5-chloro-2-methoxy-benzoic acid 2-(4-phenyl-piperazin-1-yl)-ethyl ester
   Show/Hide
C20H24ClN3O3
  1
1
Ki = 14.3 nM
 Bioactivity Info 
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CP0460082
 Compound Info 
2-[4-[[4-[3-[4-[3-[[4-[[1-[2-(4-amino-5-chloro-2-methoxybenzoyl)oxyethyl]piperidin-4-yl]methylamino]-4-oxobutyl]-(2,2-dimethylpropanoyl)amino]propyl]phenyl]propyl-(2,2-dimethylpropanoyl)amino]butanoylamino]methyl]piperidin-1-yl]ethyl 4-amino-5-chloro-2-methoxybenzoate
   Show/Hide
C62H92Cl2N8O10
  1
1
Ki = 15 nM
 Bioactivity Info 
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CP0464531
 Compound Info 
2-(4-{4-[N-(3-{3-[3-(N-{3-[(1-{2-[(4-amino-5-chloro-2-methoxyphenyl)carbonyloxy]ethyl}piperidin-4-yl)carbamoyl]propyl}-2,2-dimethylpropanamido)propyl]phenyl}propyl)-2,2-dimethylpropanamido]butanamido}piperidin-1-yl)ethyl 4-amino-5-chloro-2-methoxybenzoate
   Show/Hide
C60H88Cl2N8O10
  1
1
Ki = 15 nM
 Bioactivity Info 
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CP0116432
 Compound Info 
4-Amino-5-chloro-2-methoxy-benzoic acid 2-[4-(2-fluoro-phenyl)-piperazin-1-yl]-ethyl ester
   Show/Hide
C20H23ClFN3O3
  1
1
Ki = 16.8 nM
 Bioactivity Info 
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CP0158852
 Compound Info 
4-Amino-5-chloro-2-methoxy-benzoic acid 2-[4-(4-methoxy-phenyl)-piperazin-1-yl]-ethyl ester
   Show/Hide
C21H26ClN3O4
  1
1
Ki = 17.7 nM
 Bioactivity Info 
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CP0878443
 Compound Info 
2-(4-{4-[N-(3-{4-[3-(N-{3-[(1-{2-[(4-amino-5-chloro-2-methoxyphenyl)carbonyloxy]ethyl}piperidin-4-yl)carbamoyl]propyl}-2,2-dimethylpropanamido)prop-1-yn-1-yl]phenyl}prop-2-yn-1-yl)-2,2-dimethylpropanamido]butanamido}piperidin-1-yl)ethyl 4-amino-5-chloro-2-methoxybenzoate
   Show/Hide
C60H80Cl2N8O12
  1
1
Ki = 18 nM
 Bioactivity Info 
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CP0878598
 Compound Info 
2-{4-[(2-{N-[3-(4-{3-[N-({[(1-{2-[(4-amino-5-chloro-2-methoxyphenyl)carbonyloxy]ethyl}piperidin-4-yl)methyl]carbamoyl}methyl)-2,2-dimethylpropanamido]propyl}phenyl)propyl]-2,2-dimethylpropanamido}acetamido)methyl]piperidin-1-yl}ethyl 4-amino-5-chloro-2-methoxybenzoate
   Show/Hide
C58H84Cl2N8O12
  1
1
Ki = 19 nM
 Bioactivity Info 
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CP0269667
 Compound Info 
2-[4-({10-[(1-{2-[(4-amino-5-chloro-2-methoxyphenyl)carbonyloxy]ethyl}piperidin-4-yl)carbamoyl]decyl}carbamoyl)piperidin-1-yl]ethyl 4-amino-5-chloro-2-methoxybenzoate
   Show/Hide
C42H62Cl2N6O8
  1
1
Ki = 20 nM
 Bioactivity Info 
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CP0449155
 Compound Info 
4-[2-(4-Amino-5-chloro-2-methoxy-benzoyloxy)-ethyl]-piperazine-1-carboxylic acid ethyl ester
   Show/Hide
C17H24ClN3O5
  1
1
Ki = 23 nM
 Bioactivity Info 
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CP0911403
 Compound Info 
2-{4-[(4-{N-[3-(3-{3-[N-(3-{[(1-{2-[(4-amino-5-chloro-2-methoxyphenyl)carbonyloxy]ethyl}piperidin-4-yl)methyl]carbamoyl}propyl)-2,2-dimethylpropanamido]propyl}phenyl)propyl]-2,2-dimethylpropanamido}butanamido)methyl]piperidin-1-yl}ethyl 4-amino-5-chloro-2-methoxybenzoate
   Show/Hide
C62H92Cl2N8O12
  1
1
Ki = 23 nM
 Bioactivity Info 
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CP0504843
 Compound Info 
4-Amino-5-chloro-2-methoxy-benzoic acid 2-[4-(4-fluoro-phenyl)-piperazin-1-yl]-ethyl ester
   Show/Hide
C20H23ClFN3O3
  1
1
Ki = 23.1 nM
 Bioactivity Info 
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CP0374634
 Compound Info 
4-Amino-5-chloro-2-methoxy-benzoic acid 2-{4-[4-(5-dimethylamino-naphthalene-1-sulfonylamino)-butyl]-piperidin-1-yl}-ethyl ester
   Show/Hide
C31H41ClN4O5S
  1
1
Ki = 24 nM
 Bioactivity Info 
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CP0881790
 Compound Info 
2-{4-[(4-{N-[3-(4-{3-[N-(3-{[(1-{2-[(4-amino-5-chloro-2-methoxyphenyl)carbonyloxy]ethyl}piperidin-4-yl)methyl]carbamoyl}propyl)-2,2-dimethylpropanamido]prop-1-yn-1-yl}phenyl)prop-2-yn-1-yl]-2,2-dimethylpropanamido}butanamido)methyl]piperidin-1-yl}ethyl 4-amino-5-chloro-2-methoxybenzoate
   Show/Hide
C62H84Cl2N8O12
  1
1
Ki = 25 nM
 Bioactivity Info 
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CP0406296
 Compound Info 
4-Amino-5-chloro-2-methoxy-benzoic acid 2-{4-[8-(5-dimethylamino-naphthalene-1-sulfonylamino)-octanoyl]-piperazin-1-yl}-ethyl ester
   Show/Hide
C34H46ClN5O6S
  1
1
Ki = 31 nM
 Bioactivity Info 
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CP0453192
 Compound Info 
4-Amino-5-chloro-2-methoxy-benzoic acid 2-{4-[3-(5-dimethylamino-naphthalene-1-sulfonylamino)-propyl]-piperidin-1-yl}-ethyl ester
   Show/Hide
C30H39ClN4O5S
  1
1
Ki = 32 nM
 Bioactivity Info 
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CP0897739
 Compound Info 
2-(4-(4-(tert-butoxycarbonyl(3-(4-(3-(tert-butoxycarbonyl(4-(cyclohexylamino)-4-oxobutyl)amino)propyl)phenyl)propyl)-amino)butanamido)piperidin-1-yl)ethyl 4-Amino-5-chloro-2-methoxybenzoate
   Show/Hide
C51H79ClN6O9
  1
1
Ki = 34 nM
 Bioactivity Info 
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CP0899660
 Compound Info 
2-{4-[(4-{N-[3-(3-{3-[N-(3-{[(1-{2-[(4-amino-2-methoxyphenyl)carbonyloxy]ethyl}piperidin-4-yl)methyl]carbamoyl}propyl)-2,2-dimethylpropanamido]prop-1-yn-1-yl}phenyl)prop-2-yn-1-yl]-2,2-dimethylpropanamido}butanamido)methyl]piperidin-1-yl}ethyl 4-amino-5-chloro-2-methoxybenzoate
   Show/Hide
C62H84Cl2N8O12
  1
1
Ki = 40 nM
 Bioactivity Info 
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CP0877556
 Compound Info 
2-{4-[(2-{N-[3-(4-{3-[N-({[(1-{2-[(4-amino-5-chloro-2-methoxyphenyl)carbonyloxy]ethyl}piperidin-4-yl)methyl]carbamoyl}methyl)-2,2-dimethylpropanamido]prop-1-yn-1-yl}phenyl)prop-2-yn-1-yl]-2,2-dimethylpropanamido}acetamido)methyl]piperidin-1-yl}ethyl 4-amino-5-chloro-2-methoxybenzoate
   Show/Hide
C58H76Cl2N8O12
  1
1
Ki = 44 nM
 Bioactivity Info 
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CP0273452
 Compound Info 
1-[2-(4-amino-5-chloro-2-methoxyphenylcarbonyloxy)ethyl]-4-{10-[10-{1-[2-(4-amino-5-chloro-2-methoxyphenylcarbonyloxy)ethyl]hexahydro-4-pyridinylcarbamoyl}decyl(hexahydro-4-pyridinylmethylcarbamoylmethyl)amino]decylcarboxamido}hexahydropyridine
   Show/Hide
C60H97Cl2N9O9
  1
1
Ki = 50 nM
 Bioactivity Info 
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CP0502414
 Compound Info 
4-Amino-5-chloro-2-methoxy-benzoic acid 2-{4-[4-(6-dimethylamino-1,3-dioxo-1H,3H-benzo[de]isoquinolin-2-yl)-butyl]-piperidin-1-yl}-ethyl ester
   Show/Hide
C33H39ClN4O5
  1
1
Ki = 59 nM
 Bioactivity Info 
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CP0225714
 Compound Info 
4-Amino-5-chloro-2-methoxy-benzoic acid 2-[4-(2-methoxy-phenyl)-piperazin-1-yl]-ethyl ester
   Show/Hide
C21H26ClN3O4
  1
1
Ki = 64 nM
 Bioactivity Info 
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CP0391272
 Compound Info 
4-Amino-5-chloro-2-methoxy-benzoic acid 2-[4-(6-amino-1,3-dioxo-1H,3H-benzo[de]isoquinolin-2-ylmethyl)-piperidin-1-yl]-ethyl ester
   Show/Hide
C28H29ClN4O5
  1
1
Ki = 64 nM
 Bioactivity Info 
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CP0502406
 Compound Info 
4-Amino-5-chloro-2-methoxy-benzoic acid 2-{4-[2-(5-dimethylamino-naphthalene-1-sulfonylamino)-ethyl]-piperidin-1-yl}-ethyl ester
   Show/Hide
C29H37ClN4O5S
  1
1
Ki = 77 nM
 Bioactivity Info 
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CP0408850
 Compound Info 
4-Amino-5-chloro-2-methoxy-benzoic acid 2-{4-[11-(5-dimethylamino-naphthalene-1-sulfonylamino)-undecanoyl]-piperazin-1-yl}-ethyl ester
   Show/Hide
C37H52ClN5O6S
  1
1
Ki = 96 nM
 Bioactivity Info 
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CP0776488
 Compound Info 
4-Amino-5-chloro-2-methoxy-benzoic acid 2-[4-(3-{4-[2-(1-benzoyl-piperidin-4-ylcarbamoyl)-ethylamino]-6-benzylamino-[1,3,5]triazin-2-ylamino}-propionylamino)-piperidin-1-yl]-ethyl ester
   Show/Hide
C62H92Cl2N12O8
  1
1
Ki = 113 nM
 Bioactivity Info 
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CP0399971
 Compound Info 
4-Amino-5-chloro-2-methoxy-benzoic acid 2-{4-[3-(5-dimethylamino-naphthalene-1-sulfonylamino)-propionyl]-piperazin-1-yl}-ethyl ester
   Show/Hide
C29H36ClN5O6S
  1
1
Ki = 116 nM
 Bioactivity Info 
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CP0246165
 Compound Info 
4-Amino-5-chloro-2-methoxy-benzoic acid 2-[4-(3-chloro-phenyl)-piperazin-1-yl]-ethyl ester
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C20H23Cl2N3O3
  1
1
Ki = 162 nM
 Bioactivity Info 
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CP0448456
 Compound Info 
4-Amino-5-chloro-2-methoxy-benzoic acid 2-{4-[6-(5-dimethylamino-naphthalene-1-sulfonylamino)-hexanoyl]-piperazin-1-yl}-ethyl ester
   Show/Hide
C32H42ClN5O6S
  1
1
Ki = 180 nM
 Bioactivity Info 
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CP0449396
 Compound Info 
4-Amino-5-chloro-2-methoxy-benzoic acid 2-[4-(6-dimethylamino-1,3-dioxo-1H,3H-benzo[de]isoquinolin-2-ylmethyl)-piperidin-1-yl]-ethyl ester
   Show/Hide
C30H33ClN4O5
  1
1
Ki = 181 nM
 Bioactivity Info 
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CP0453489
 Compound Info 
4-Amino-5-chloro-2-methoxy-benzoic acid 2-{4-[4-(5-dimethylamino-naphthalene-1-sulfonylamino)-butyryl]-piperazin-1-yl}-ethyl ester
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C30H38ClN5O6S
  1
1
Ki = 183 nM
 Bioactivity Info 
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CP0535310
 Compound Info 
4-Amino-5-chloro-2-methoxy-benzoic acid 2-[4-(3-trifluoromethyl-phenyl)-piperazin-1-yl]-ethyl ester
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C21H23ClF3N3O3
  1
1
Ki = 199.2 nM
 Bioactivity Info 
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CP0529762
 Compound Info 
4-Amino-5-chloro-2-methoxy-benzoic acid 2-(4-benzyl-piperazin-1-yl)-ethyl ester
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C21H26ClN3O3
  1
1
Ki = 240 nM
 Bioactivity Info 
   TI
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CP0448513
 Compound Info 
4-Amino-5-chloro-2-methoxy-benzoic acid 2-[4-(5-dimethylamino-naphthalene-1-sulfonylamino)-piperidin-1-yl]-ethyl ester
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C27H33ClN4O5S
  1
1
Ki = 264 nM
 Bioactivity Info 
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CP0225715
 Compound Info 
4-Amino-5-chloro-2-methoxy-benzoic acid 2-[4-(2-chloro-phenyl)-piperazin-1-yl]-ethyl ester
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C20H23Cl2N3O3
  1
1
Ki = 296 nM
 Bioactivity Info 
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CP0265346
 Compound Info 
4-Amino-5-chloro-2-methoxy-benzoic acid 2-[4-(4-chloro-phenyl)-piperazin-1-yl]-ethyl ester
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C20H23Cl2N3O3
  1
1
Ki = 715 nM
 Bioactivity Info 
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CP0441827
 Compound Info 
4-Amino-5-chloro-2-methoxy-benzoic acid 2-{4-[2-(5-dimethylamino-naphthalene-1-sulfonylamino)-acetyl]-piperazin-1-yl}-ethyl ester
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C28H34ClN5O6S
  1
1
Ki = 1720 nM
 Bioactivity Info 
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CP0439606
 Compound Info 
4-[2-(4-Amino-5-chloro-2-methoxy-benzoyloxy)-ethyl]-piperazine-1-carboxylic acid tert-butyl ester
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C19H28ClN3O5
  1
1
Ki > 1000 nM
 Bioactivity Info 
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CP0496435
 Compound Info 
4-Amino-5-chloro-2-methoxy-benzoic acid 2-piperazin-1-yl-ethyl ester
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C14H20ClN3O3
  1
1
Ki > 1000 nM
 Bioactivity Info 
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CP0511290
 Compound Info 
4-Amino-5-chloro-2-methoxy-benzoic acid 2-(4-naphthalen-1-yl-piperazin-1-yl)-ethyl ester
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C24H26ClN3O3
  1
1
Ki > 1000 nM
 Bioactivity Info 
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CP0529761
 Compound Info 
4-Amino-5-chloro-2-methoxy-benzoic acid 2-(4-methyl-piperazin-1-yl)-ethyl ester
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C15H22ClN3O3
  1
1
Ki > 1000 nM
 Bioactivity Info 
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Protein ID: PT00819, 5-hydroxytryptamine receptor 1A
 Protein Info 
Protein ID: PT01650, Alpha-2A adrenergic receptor
 Protein Info 
Protein ID: PT02026, Alpha-2B adrenergic receptor
 Protein Info 
Protein ID: PT01598, Alpha-2C adrenergic receptor
 Protein Info 
Protein ID: PT00623, Amino acid transporter
 Protein Info 
Protein ID: PT00957, D(2) dopamine receptor
 Protein Info 
Protein ID: PT01005, D(2) dopamine receptor
 Protein Info 
Protein ID: PT01200, Delta-type opioid receptor
 Protein Info 
Protein ID: PT01526, Delta-type opioid receptor
 Protein Info 
Protein ID: PT01173, Histamine H3 receptor
 Protein Info 
Protein ID: PT01194, Histamine H3 receptor
 Protein Info 
Protein ID: PT00983, Kappa-type opioid receptor
 Protein Info 
Protein ID: PT01515, Mu-type opioid receptor
 Protein Info 
Protein ID: PT01549, Mu-type opioid receptor
 Protein Info 
Protein ID: PT06389, Neuromedin-B receptor
 Protein Info 
Protein ID: PT01653, Neuropeptide Y receptor type 5
 Protein Info 
Protein ID: PT05434, P2Y purinoceptor 14
 Protein Info 
Protein ID: PT07695, P2Y purinoceptor 14
 Protein Info 
Protein ID: PT01973, Sigma non-opioid intracellular receptor 1
 Protein Info 
Protein ID: PT06071, Solute carrier family 6 member 5
 Protein Info 
Protein ID: PT02766, Solute carrier family 6 member 9
 Protein Info 
Cell Viability or Cytotoxicity Assay
Compound ID Compound Name Compound Formula
CP0041156
 Compound Info 
4-[2-(4-amino-1,2,5-oxadiazol-3-yl)-1-ethyl-7-[(3S)-piperidin-3-ylmethoxy]-1H-imidazo[4,5-c]pyridin-4-yl]-2-methylbut-3-yn-2-ol
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 C21H27N7O3  1
1
IC50 = 14500 nM
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CP0558268
 Compound Info 
2-[8-[[2-[bis(pyridin-2-ylmethyl)amino]acetyl]amino]-2-(4-chlorophenyl)imidazo[1,2-a]pyridin-3-yl]-N,N-dipropylacetamide
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 C35H38ClN7O2  1
1
IC50 = 270 nM
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Protein family and CMB statistics Related to the Cell Line
Cell Lines Derived from the same Tissue Source (Brain)
Cell Line Name Organism Disease
TS603
 Cell Line Info 
Homo sapiens (Human) Anaplastic oligodendroglioma
H4
 Cell Line Info 
Homo sapiens (Human) Astrocytoma
1321N1
 Cell Line Info 
Homo sapiens (Human) Astrocytoma
SNB-19
 Cell Line Info 
Homo sapiens (Human) Astrocytoma
U-251MG
 Cell Line Info 
Homo sapiens (Human) Astrocytoma
U-373MG ATCC
 Cell Line Info 
Homo sapiens (Human) Astrocytoma
LN-308
 Cell Line Info 
Homo sapiens (Human) Astrocytoma
CCF-STTG1
 Cell Line Info 
Homo sapiens (Human) Astrocytoma
LN-319
 Cell Line Info 
Homo sapiens (Human) Astrocytoma
P2X7-1321N1
 Cell Line Info 
Homo sapiens (Human) Astrocytoma
MDA-MB-361
 Cell Line Info 
Homo sapiens (Human) Breast adenocarcinoma
JEG-3
 Cell Line Info 
Homo sapiens (Human) Gestational choriocarcinoma
D3 [Human glioblastoma]
 Cell Line Info 
Homo sapiens (Human) Glioblastoma
LN-229
 Cell Line Info 
Homo sapiens (Human) Glioblastoma
LN-18
 Cell Line Info 
Homo sapiens (Human) Glioblastoma
A-172
 Cell Line Info 
Homo sapiens (Human) Glioblastoma
UC-11MG
 Cell Line Info 
Homo sapiens (Human) Glioblastoma
T98G
 Cell Line Info 
Homo sapiens (Human) Glioblastoma
LN229-V6R
 Cell Line Info 
Homo sapiens (Human) Glioblastoma
SF539
 Cell Line Info 
Homo sapiens (Human) Gliosarcoma
MED1
 Cell Line Info 
Homo sapiens (Human) Medulloblastoma, non-WNT/non-SHH, group 4
Kelly
 Cell Line Info 
Homo sapiens (Human) Neuroblastoma
PFSK-1
 Cell Line Info 
Homo sapiens (Human) Primitive neuroectodermal tumor
DU145
 Cell Line Info 
Homo sapiens (Human) Prostate carcinoma
DU145-TxR
 Cell Line Info 
Homo sapiens (Human) Prostate carcinoma
GL261
 Cell Line Info 
Mus musculus (Mouse) Mouse glioblastoma
C6-BU-1
 Cell Line Info 
Rattus norvegicus (Rat) Rat malignant glioma
RG2
 Cell Line Info 
Rattus norvegicus (Rat) Rat malignant glioma
ReNcell VM
 Cell Line Info 
Homo sapiens (Human) -
hCMEC/D3
 Cell Line Info 
Homo sapiens (Human) -
BV-2
 Cell Line Info 
Mus musculus (Mouse) -
C17.2
 Cell Line Info 
Mus musculus (Mouse) -
ScGT1
 Cell Line Info 
Mus musculus (Mouse) -
bEnd.4
 Cell Line Info 
Mus musculus (Mouse) -
N39
 Cell Line Info 
Mus musculus (Mouse) -
GT1-7
 Cell Line Info 
Mus musculus (Mouse) -
N27-A
 Cell Line Info 
Rattus norvegicus (Rat) -
RBE4
 Cell Line Info 
Rattus norvegicus (Rat) -