General Information of the Cell Line
Cell Line ID
CL000119
Cell Line Name
DU145
Synonyms
DU-145
Du-145
DU 145
DU_145
DU.145
Duke University 145
Category
Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0105
Tissue Information
Brain
Disease
Prostate carcinoma (NCIt: C4863)
Map of Molecular Bioactivity Related to the Cell Line
Map of Molecular Bioactivity Related to the Cell Line

Cell Line
Protein
Compound

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Cell Line
Protein ID: PT01430, 3-oxo-5-alpha-steroid 4-dehydrogenase 1
 Protein Info 
Compound ID Compound Name Compound Formula
CP0472249
 Compound Info 
N-[(1S,5aR,9aR,11aS)-6,9a,11a-trimethyl-7-oxo-2,3,3a,3b,4,5,5a,8,9,9b,10,11-dodecahydro-1H-indeno[5,4-f]quinolin-1-yl]-N-pentylformamide
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C25H42N2O2
  1
1
IC50 = 0.91 nM
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CP0453967
 Compound Info 
N-[(1S,5aR,9aR,11aS)-6,9a,11a-trimethyl-7-oxo-2,3,3a,3b,4,5,5a,8,9,9b,10,11-dodecahydro-1H-indeno[5,4-f]quinolin-1-yl]-N-pentylpentanamide
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C29H50N2O2
  1
1
IC50 = 1.77 nM
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CP0441797
 Compound Info 
N-[(1S,5aR,9aR,11aS)-6,9a,11a-trimethyl-7-oxo-2,3,3a,3b,4,5,5a,8,9,9b,10,11-dodecahydro-1H-indeno[5,4-f]quinolin-1-yl]-N-(4-methoxyphenyl)benzamide
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C33H42N2O3
  1
1
IC50 = 2.11 nM
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CP0505951
 Compound Info 
N-[(1S,5aR,9aR,11aS)-6,9a,11a-trimethyl-7-oxo-2,3,3a,3b,4,5,5a,8,9,9b,10,11-dodecahydro-1H-indeno[5,4-f]quinolin-1-yl]-N-(3-methylbutyl)formamide
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C25H42N2O2
  1
1
IC50 = 2.19 nM
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CP0399791
 Compound Info 
N-[(1S,5aR,9aR,11aS)-6,9a,11a-trimethyl-7-oxo-2,3,3a,3b,4,5,5a,8,9,9b,10,11-dodecahydro-1H-indeno[5,4-f]quinolin-1-yl]-N-(3,3-dimethylbutyl)formamide
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C26H44N2O2
  1
1
IC50 = 2.35 nM
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CP0399792
 Compound Info 
5-Bromo-pentanoic acid pentyl-((4aR,6aS,7S,11aR)-1,4a,6a-trimethyl-2-oxo-hexadecahydro-indeno[5,4-f]quinolin-7-yl)-amide
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C29H49BrN2O2
  1
1
IC50 = 2.42 nM
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CP0430286
 Compound Info 
N-[(1S,5aR,9aR,11aS)-6,9a,11a-trimethyl-7-oxo-2,3,3a,3b,4,5,5a,8,9,9b,10,11-dodecahydro-1H-indeno[5,4-f]quinolin-1-yl]-N-phenylbenzamide
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C32H40N2O2
  1
1
IC50 = 2.93 nM
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CP0514242
 Compound Info 
N-[(1S,5aR,9aR,11aS)-6,9a,11a-trimethyl-7-oxo-2,3,3a,3b,4,5,5a,8,9,9b,10,11-dodecahydro-1H-indeno[5,4-f]quinolin-1-yl]-N-butylformamide
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C24H40N2O2
  1
1
IC50 = 3.05 nM
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CP0515956
 Compound Info 
N-[(1S,5aR,9aR,11aS)-6,9a,11a-trimethyl-7-oxo-2,3,3a,3b,4,5,5a,8,9,9b,10,11-dodecahydro-1H-indeno[5,4-f]quinolin-1-yl]-N-pentylbenzamide
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C31H46N2O2
  1
1
IC50 = 3.22 nM
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CP0509782
 Compound Info 
N-[(1S,5aR,9aR,11aS)-6,9a,11a-trimethyl-7-oxo-2,3,3a,3b,4,5,5a,8,9,9b,10,11-dodecahydro-1H-indeno[5,4-f]quinolin-1-yl]-N-pentylbutanamide
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C28H48N2O2
  1
1
IC50 = 3.31 nM
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CP0150571
 Compound Info 
(1S,3aS,3bS,5aR,9aR,9bS,11aS)-N,N-diethyl-6,9a,11a-trimethyl-7-oxo-2,3,3a,3b,4,5,5a,8,9,9b,10,11-dodecahydro-1H-indeno[5,4-f]quinoline-1-carboxamide
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C24H40N2O2
  1
1
IC50 = 4.14 nM
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CP0462979
 Compound Info 
N-[(1S,5aR,9aR,11aS)-6,9a,11a-trimethyl-7-oxo-2,3,3a,3b,4,5,5a,8,9,9b,10,11-dodecahydro-1H-indeno[5,4-f]quinolin-1-yl]-N-pentylpropanamide
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C27H46N2O2
  1
1
IC50 = 4.56 nM
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CP0453764
 Compound Info 
N-[(1S,5aR,9aR,11aS)-6,9a,11a-trimethyl-7-oxo-2,3,3a,3b,4,5,5a,8,9,9b,10,11-dodecahydro-1H-indeno[5,4-f]quinolin-1-yl]-N-propylformamide
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C23H38N2O2
  1
1
IC50 = 5.08 nM
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CP0375240
 Compound Info 
N-[(1S,5aR,9aR,11aS)-6,9a,11a-trimethyl-7-oxo-2,3,3a,3b,4,5,5a,8,9,9b,10,11-dodecahydro-1H-indeno[5,4-f]quinolin-1-yl]-N-(4-methoxyphenyl)-2-methylpropanamide
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C30H44N2O3
  1
1
IC50 = 5.44 nM
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CP0483644
 Compound Info 
N-[(1S,5aR,9aR,11aS)-6,9a,11a-trimethyl-7-oxo-2,3,3a,3b,4,5,5a,8,9,9b,10,11-dodecahydro-1H-indeno[5,4-f]quinolin-1-yl]-N-benzylformamide
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C27H38N2O2
  1
1
IC50 = 5.63 nM
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CP0502400
 Compound Info 
N-[(1S,5aR,9aR,11aS)-6,9a,11a-trimethyl-7-oxo-2,3,3a,3b,4,5,5a,8,9,9b,10,11-dodecahydro-1H-indeno[5,4-f]quinolin-1-yl]-N-hexylformamide
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C26H44N2O2
  1
1
IC50 = 7.25 nM
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CP0403856
 Compound Info 
N-[(1S,5aR,9aR,11aS)-6,9a,11a-trimethyl-7-oxo-2,3,3a,3b,4,5,5a,8,9,9b,10,11-dodecahydro-1H-indeno[5,4-f]quinolin-1-yl]-N-(2-methylpropyl)formamide
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C24H40N2O2
  1
1
IC50 = 7.31 nM
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CP0440219
 Compound Info 
N-[(1S,5aR,9aR,11aS)-6,9a,11a-trimethyl-7-oxo-2,3,3a,3b,4,5,5a,8,9,9b,10,11-dodecahydro-1H-indeno[5,4-f]quinolin-1-yl]-N-propan-2-ylformamide
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C23H38N2O2
  1
1
IC50 = 9.53 nM
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CP0432509
 Compound Info 
N-[(1S,5aR,9aR,11aS)-6,9a,11a-trimethyl-7-oxo-2,3,3a,3b,4,5,5a,8,9,9b,10,11-dodecahydro-1H-indeno[5,4-f]quinolin-1-yl]-N-heptylformamide
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C27H46N2O2
  1
1
IC50 = 9.57 nM
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CP0471763
 Compound Info 
N-[(1S,5aR,9aR,11aS)-6,9a,11a-trimethyl-7-oxo-2,3,3a,3b,4,5,5a,8,9,9b,10,11-dodecahydro-1H-indeno[5,4-f]quinolin-1-yl]-2-methyl-N-phenylpropanamide
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C29H42N2O2
  1
1
IC50 = 10.5 nM
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CP0453223
 Compound Info 
N-[(1S,5aR,9aR,11aS)-6,9a,11a-trimethyl-7-oxo-2,3,3a,3b,4,5,5a,8,9,9b,10,11-dodecahydro-1H-indeno[5,4-f]quinolin-1-yl]-N-pentan-3-ylformamide
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C25H42N2O2
  1
1
IC50 = 10.6 nM
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CP0455135
 Compound Info 
N-[(1S,5aR,9aR,11aS)-6,9a,11a-trimethyl-7-oxo-2,3,3a,3b,4,5,5a,8,9,9b,10,11-dodecahydro-1H-indeno[5,4-f]quinolin-1-yl]-N-cyclopropylformamide
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C23H36N2O2
  1
1
IC50 = 11.2 nM
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CP0472243
 Compound Info 
N-[(1S,5aR,9aR,11aS)-6,9a,11a-trimethyl-7-oxo-2,3,3a,3b,4,5,5a,8,9,9b,10,11-dodecahydro-1H-indeno[5,4-f]quinolin-1-yl]-N-butylacetamide
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C25H42N2O2
  1
1
IC50 = 11.8 nM
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CP0399860
 Compound Info 
N-[(1S,5aR,9aR,11aS)-6,9a,11a-trimethyl-7-oxo-2,3,3a,3b,4,5,5a,8,9,9b,10,11-dodecahydro-1H-indeno[5,4-f]quinolin-1-yl]-N-cyclohexylformamide
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C26H42N2O2
  1
1
IC50 = 11.9 nM
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CP0462851
 Compound Info 
N-[(1S,5aR,9aR,11aS)-6,9a,11a-trimethyl-7-oxo-2,3,3a,3b,4,5,5a,8,9,9b,10,11-dodecahydro-1H-indeno[5,4-f]quinolin-1-yl]-N-octylformamide
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C28H48N2O2
  1
1
IC50 = 16.9 nM
 Bioactivity Info 
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CP0043937
 Compound Info 
(17beta-(N-tert-butylcarbamoyl)-4-aza-5alpha-androst-1-en-3-one
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C23H36N2O2
  2
1
IC50 = 26.3 nM
 Bioactivity Info 
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2
IC50 = 40 nM
 Bioactivity Info 
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CP0381016
 Compound Info 
N-[(1S,5aR,9aR,11aS)-6,9a,11a-trimethyl-7-oxo-2,3,3a,3b,4,5,5a,8,9,9b,10,11-dodecahydro-1H-indeno[5,4-f]quinolin-1-yl]-N-methylformamide
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C21H34N2O2
  1
1
IC50 = 29 nM
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CP0447880
 Compound Info 
N-[(1S,5aR,9aR,11aS)-6,9a,11a-trimethyl-7-oxo-2,3,3a,3b,4,5,5a,8,9,9b,10,11-dodecahydro-1H-indeno[5,4-f]quinolin-1-yl]-2-methyl-N-(4-nitrophenyl)propanamide
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C29H41N3O4
  1
1
IC50 = 32.8 nM
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CP0469224
 Compound Info 
N-[(1S,5aR,9aR,11aS)-6,9a,11a-trimethyl-7-oxo-2,3,3a,3b,4,5,5a,8,9,9b,10,11-dodecahydro-1H-indeno[5,4-f]quinolin-1-yl]-2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]propanamide
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C30H40F3N3O4
  1
1
IC50 = 59.8 nM
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CP0867572
 Compound Info 
(7aS,8S,10aR)-7a-Methyl-2-oxo-2,3,4,6,7,7a,8,9,10,10a,11,12-dodecahydro-indeno[4,5-c]quinolizine-8-carboxylic acid tert-butylamide; compound with (7aS,8S,10aS)-7a-methyl-2-oxo-2,3,4,7,7a,8,9,10,10a,10b,11,12-dodecahydro-indeno[4,5-c]quinolizine-8-carboxylic acid tert-butylamide
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C44H64N4O4
  1
1
IC50 = 127 nM
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CP0846079
 Compound Info 
(7aS,10aS)-7a-Methyl-3,4,6,7,7a,9,10,10a,11,12-decahydro-indeno[4,5-c]quinolizine-2,8-dione; compound with (7aS,10aS)-7a-methyl-3,4,7,7a,9,10,10a,10b,11,12-decahydro-indeno[4,5-c]quinolizine-2,8-dione
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C34H42N2O4
  1
1
IC50 = 263 nM
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CP0498421
 Compound Info 
(5aS,7aS,10aS,10bS)-7a-Methyl-3,4,5a,6,7,7a,9,10,10a,10b,11,12-dodecahydro-indeno[4,5-c]quinolizine-2,8-dione
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C17H23NO2
  1
1
IC50 = 299 nM
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CP0448985
 Compound Info 
(5aS,7aS,8S,10aS,10bS)-8-Hydroxy-7a-methyl-3,4,6,7,7a,8,9,10,10a,10b,11,12-dodecahydro-5aH-indeno[4,5-c]quinolizin-2-one
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C17H25NO2
  1
1
IC50 = 409 nM
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CP0708124
 Compound Info 
17-(2-Hydroxyimino-propyl)-10,13-dimethyl-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-cyclopenta[a]phenanthren-3-one
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C22H33NO2
  1
1
IC50 = 900 nM
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CP0774469
 Compound Info 
17-(2-Hydroxyimino-propyl)-10,13-dimethyl-1,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-2H-cyclopenta[a]phenanthrene-3,6-dione
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C22H31NO3
  1
1
IC50 = 900 nM
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CP0394369
 Compound Info 
(5aS,7aS,8S,10aS,10bS)-7a-Methyl-2-oxo-2,3,4,5a,6,7,7a,8,9,10,10a,10b,11,12-tetradecahydro-indeno[4,5-c]quinolizine-8-carboxylic acid tert-butylamide
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C22H34N2O2
  1
1
IC50 = 1134 nM
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CP0704726
 Compound Info 
17-(1-Hydroxyimino-ethyl)-10,13-dimethyl-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-cyclopenta[a]phenanthren-3-one
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C21H31NO2
  1
1
IC50 = 1630 nM
 Bioactivity Info 
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CP0463729
 Compound Info 
N-[(1S,9aR,11aS)-6,9a,11a-trimethyl-7-oxo-2,3,3a,3b,4,8,9,9b,10,11-decahydro-1H-indeno[5,4-f]quinolin-1-yl]-N-methylformamide
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C21H32N2O2
  1
1
IC50 = 1900 nM
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CP0829272
 Compound Info 
(10,13-Dimethyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)-acetaldehyde oxime
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C21H31NO2
  1
1
IC50 = 1950 nM
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CP0383371
 Compound Info 
N-[(1S,5aR,9aR,11aS)-9a,11a-dimethyl-7-oxo-1,2,3,3a,3b,4,5,5a,6,8,9,9b,10,11-tetradecahydroindeno[5,4-f]quinolin-1-yl]-N-methylformamide
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C20H32N2O2
  1
1
IC50 = 3700 nM
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CP0701225
 Compound Info 
17-(1-Hydroxyimino-ethyl)-10,13-dimethyl-1,2,6,7,8,9,10,11,12,13-decahydro-cyclopenta[a]phenanthren-3-one
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C21H27NO2
  1
1
IC50 > 10000 nM
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CP0783030
 Compound Info 
17-(1-Hydroxyimino-ethyl)-10,13-dimethyl-1,2,6,7,8,9,10,11,12,13,14,15-dodecahydro-cyclopenta[a]phenanthren-3-one
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C21H29NO2
  1
1
IC50 > 10000 nM
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CP0790468
 Compound Info 
17-(1-Hydroxyimino-ethyl)-10,13-dimethyl-1,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-2H-cyclopenta[a]phenanthrene-3,6-dione
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C21H29NO3
  1
1
IC50 > 10000 nM
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CP0534568
 Compound Info 
(5aS,7aS,10aS,10bS,12aS)-7a-Methyl-tetradecahydro-indeno[4,5-c]quinolizine-2,8-dione
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C17H25NO2
  1
1
IC50 > 100000 nM
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CP0862900
 Compound Info 
(6aS,9aS)-6a-Methyl-2,3,5,6,6a,8,9,9a,10,11-decahydro-1H-indeno[5,4-f]quinoline-4,7-dione; compound with (6aS,9aS)-6a-methyl-2,3,6,6a,8,9,9a,9b,10,11-decahydro-1H-indeno[5,4-f]quinoline-4,7-dione
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C34H42N2O4
  1
1
IC50 > 100000 nM
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CP0440198
 Compound Info 
N-[(1S,5aR,9aR,11aS)-9a,11a-dimethyl-7-oxo-1,2,3,3a,3b,4,5,5a,6,9b,10,11-dodecahydroindeno[5,4-f]quinolin-1-yl]-N-methylformamide
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C20H30N2O2
  1
1
IC50 > 100 nM
 Bioactivity Info 
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CP0502335
 Compound Info 
N-[(1S,5aR,9aR,11aS)-6,9a,11a-trimethyl-7-oxo-2,3,3a,3b,4,5,5a,9b,10,11-decahydro-1H-indeno[5,4-f]quinolin-1-yl]-N-methylformamide
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C21H32N2O2
  1
1
IC50 > 100 nM
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Protein ID: PT01489, 3-oxo-5-alpha-steroid 4-dehydrogenase 2
 Protein Info 
Protein ID: PT01201, Hepatocyte growth factor receptor
 Protein Info 
Protein ID: PT02357, Neuropilin-1
 Protein Info 
Cell Viability or Cytotoxicity Assay
Compound ID Compound Name Compound Formula
CP0003433
 Compound Info 
(Arylindolyl)maleimide deriv. 27
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 C21H16N4O2  1
1
LC50 > 100000 nM
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CP0003832
 Compound Info 
N'-hydroxy-N-phenyloctanediamide
   Show/Hide
 C14H20N2O3  1
1
IC50 = 2490 nM
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CP0006369
 Compound Info 
6-[3-[4-[1-(5-cyanopentyl)indol-3-yl]-1-hydroxy-2,5-dioxopyrrol-3-yl]indol-1-yl]hexanenitrile
   Show/Hide
 C32H31N5O3  1
1
GI50 = 27800 nM
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CP0018092
 Compound Info 
(1R,2R,5S,8R,9R,10R,13R,14R,17S,19R)-17-hydroxy-1,2,14,18,18-pentamethyl-8-(prop-1-en-2-yl)pentacyclo[11.8.0.0^{2,10}.0^{5,9}.0^{14,19}]henicosane-5-carboxylic acid
   Show/Hide
 C30H48O3  1
1
IC50 = 37000 nM
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CP0024501
 Compound Info 
(1S,5S,6R,9S,15E,20R)-6-[(2S)-butan-2-yl]-5-hydroxy-20-(2-methylsulfanylethyl)-2-oxa-11,12-dithia-7,19,22-triazabicyclo[7.7.6]docos-15-ene-3,8,18,21-tetrone
   Show/Hide
 C23H37N3O6S3  1
1
GI50 = 3.1 nM
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CP0046304
 Compound Info 
(4-bromophenyl) 6-[4-[[8-(hydroxyamino)-8-oxooctanoyl]amino]phenyl]-5-(4-hydroxyphenyl)-7-oxabicyclo[2.2.1]hept-5-ene-2-sulfonate
   Show/Hide
 C32H33BrN2O8S  1
1
IC50 = 11300 nM
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CP0046307
 Compound Info 
8-[4-[3-(4-hydroxyphenyl)-6-[4-(trifluoromethyl)phenoxy]sulfonyl-7-oxabicyclo[2.2.1]hept-2-en-2-yl]anilino]-8-oxooctanoic acid
   Show/Hide
 C33H32F3NO8S  1
1
IC50 = 77000 nM
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CP0047127
 Compound Info 
5-chloro-N-(2-chloro-4-nitrophenyl)-2-hydroxybenzamide
   Show/Hide
 C13H8Cl2N2O4  1
1
IC50 = 700 nM
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CP0048996
 Compound Info 
CAS_74191-85-8
   Show/Hide
 C23H25N5O5  3
1
EC50 > 100000 nM
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2
IC50 = 30560 nM
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3
IC50 = 37440 nM
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CP0056229
 Compound Info 
8-[3-[[5,6-bis(4-hydroxyphenyl)-7-oxabicyclo[2.2.1]hept-5-en-2-yl]sulfonyloxy]anilino]-8-oxooctanoic acid
   Show/Hide
 C32H33NO9S  1
1
IC50 > 100000 nM
   TI
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CP0058811
 Compound Info 
8-[4-[3-(4-hydroxyphenyl)-6-(3-methoxyphenoxy)sulfonyl-7-oxabicyclo[2.2.1]hept-2-en-2-yl]anilino]-8-oxooctanoic acid
   Show/Hide
 C33H35NO9S  1
1
IC50 = 53800 nM
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CP0061300
 Compound Info 
N-[(4-bromophenyl)methyl]-2-methyl-N-[(E)-3-(3,4,5-trimethoxyphenyl)prop-2-enoyl]prop-2-enamide
   Show/Hide
 C23H24BrNO5  1
1
GI50 = 900 nM
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   TS
CP0073095
 Compound Info 
2,4-difluoro-N-[2-methoxy-5-[4-methyl-2-(methylamino)-8-(oxan-4-yloxy)quinazolin-6-yl]pyridin-3-yl]benzenesulfonamide
   Show/Hide
 C27H27F2N5O5S  1
1
IC50 = 5200 nM
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CP0077619
 Compound Info 
Andrographolide
   Show/Hide
 C20H30O5  1
1
GI50 = 3000 nM
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CP0083429
 Compound Info 
5-[4-[[(19S)-19-ethyl-19-hydroxy-14,18-dioxo-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2(11),3,5,7,9,15(20)-heptaen-7-yl]oxymethyl]triazol-1-yl]-N-hydroxypentanamide
   Show/Hide
 C28H28N6O7  1
1
IC50 = 2500 nM
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CP0090639
 Compound Info 
N-benzyl-2-[2-[methyl(5-pyrrolidin-1-ylpentyl)amino]-3-(4-phenylphenyl)-4H-quinazolin-4-yl]acetamide
   Show/Hide
 C39H45N5O  1
1
GI50 = 2490 nM
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CP0093215
 Compound Info 
8-[4-[6-(4-bromophenoxy)sulfonyl-3-(4-hydroxyphenyl)-7-oxabicyclo[2.2.1]hept-2-en-2-yl]anilino]-8-oxooctanoic acid
   Show/Hide
 C32H32BrNO8S  1
1
IC50 > 100000 nM
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CP0095649
 Compound Info 
(2E)-3-{4-[3-(adamantan-1-yl)-4-aminophenyl]-3-chlorophenyl}prop-2-enoic acid
   Show/Hide
 C25H26ClNO2  1
1
IC50 = 1300 nM
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CP0095953
 Compound Info 
ENZALUTAMIDE
   Show/Hide
 C21H16F4N4O2S  2
1
IC50 = 32270 nM
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2
IC50 = 49300 nM
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CP0106219
 Compound Info 
6-(5-Bromo-2-ethoxy-phenyl)-N*4*-(4-chloro-phenyl)-pyrimidine-2,4-diamine
   Show/Hide
 C18H16BrClN4O  1
1
IC50 = 80 nM
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CP0114952
 Compound Info 
8-[4-[3-(4-hydroxyphenyl)-6-naphthalen-2-yloxysulfonyl-7-oxabicyclo[2.2.1]hept-2-en-2-yl]anilino]-8-oxooctanoic acid
   Show/Hide
 C36H35NO8S  1
1
IC50 = 58300 nM
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   TS
CP0114954
 Compound Info 
8-[4-[3-(4-hydroxyphenyl)-6-[2-(trifluoromethyl)phenoxy]sulfonyl-7-oxabicyclo[2.2.1]hept-2-en-2-yl]anilino]-8-oxooctanoic acid
   Show/Hide
 C33H32F3NO8S  1
1
IC50 > 100000 nM
   TI
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   TS
CP0117034
 Compound Info 
2,4-difluoro-N-[2-methoxy-5-[4-methyl-2-(methylamino)-8-[(3R)-oxolan-3-yl]oxyquinazolin-6-yl]pyridin-3-yl]benzenesulfonamide
   Show/Hide
 C26H25F2N5O5S  1
1
IC50 = 6500 nM
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CP0122758
 Compound Info 
8-[4-[6-(2,6-dimethylphenoxy)sulfonyl-3-(4-hydroxyphenyl)-7-oxabicyclo[2.2.1]hept-2-en-2-yl]anilino]-8-oxooctanoic acid
   Show/Hide
 C34H37NO8S  1
1
IC50 > 100000 nM
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CP0128740
 Compound Info 
6-butyl-4-methyl-7-(2-methylphenyl)purino[7,8-a]imidazole-1,3-dione
   Show/Hide
 C19H21N5O2  1
1
IC50 = 11200 nM
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CP0144490
 Compound Info 
N-(3,4-dimethoxyphenyl)-2-(2-pyridin-4-ylethyl)pyrazole-3-carboxamide
   Show/Hide
 C19H20N4O3  1
1
GI50 = 220 nM
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CP0154554
 Compound Info 
[4-(1-methylimidazole-4-carbonyl)piperazin-1-yl]-[4-(tetrazolo[1,5-a]quinoxalin-4-ylamino)phenyl]methanone
   Show/Hide
 C24H22N10O2  1
1
GI50 = 100 nM
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CP0163636
 Compound Info 
5-(2,5-Dihydroxy-benzylamino)-2-hydroxy-N-(1,2,3,4-tetrahydro-naphthalen-2-yl)-benzamide
   Show/Hide
 C24H24N2O4  1
1
GI50 = 17000 nM
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CP0166875
 Compound Info 
(2E)-3-{4-[3-(adamantan-1-yl)-4-fluorophenyl]-3-chlorophenyl}prop-2-enoic acid
   Show/Hide
 C25H24ClFO2  1
1
IC50 = 16000 nM
   TI
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   TS
CP0176598
 Compound Info 
N-[4-[2-[(2S,3S,5R)-2-[[tert-butyl(dimethyl)silyl]oxymethyl]-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-3-yl]-1,3-dithian-2-yl]phenyl]-N'-hydroxyoctanediamide
   Show/Hide
 C34H52N4O7S2Si  1
1
GI50 = 3980 nM
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CP0179329
 Compound Info 
Alphitolic acid
   Show/Hide
 C30H48O4  1
1
IC50 = 70000 nM
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CP0184260
 Compound Info 
N-[2-(4-bromophenyl)ethyl]-5-[(2,5-dihydroxyphenyl)methylamino]-2-hydroxybenzamide
   Show/Hide
 C22H21BrN2O4  1
1
GI50 = 16000 nM
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CP0185108
 Compound Info 
naphthalen-2-yl 6-[4-[[8-(hydroxyamino)-8-oxooctanoyl]amino]phenyl]-5-(4-hydroxyphenyl)-7-oxabicyclo[2.2.1]hept-5-ene-2-sulfonate
   Show/Hide
 C36H36N2O8S  1
1
IC50 = 12400 nM
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CP0190702
 Compound Info 
Anilinoquinazoline, 4c
   Show/Hide
 C14H11ClN4  1
1
IC50 = 34140 nM
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CP0193114
 Compound Info 
8-[4-[3-(4-hydroxyphenyl)-6-(2-methoxyphenoxy)sulfonyl-7-oxabicyclo[2.2.1]hept-2-en-2-yl]anilino]-8-oxooctanoic acid
   Show/Hide
 C33H35NO9S  1
1
IC50 > 100000 nM
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CP0194921
 Compound Info 
5-(2,5-Dihydroxy-benzylamino)-2-hydroxy-N-[2-(4-methoxy-phenyl)-ethyl]-benzamide
   Show/Hide
 C23H24N2O5  1
1
GI50 = 21000 nM
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CP0199030
 Compound Info 
phenyl 6-[4-[[8-(hydroxyamino)-8-oxooctanoyl]amino]phenyl]-5-(4-hydroxyphenyl)-7-oxabicyclo[2.2.1]hept-5-ene-2-sulfonate
   Show/Hide
 C32H34N2O8S  1
1
IC50 = 37700 nM
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CP0224766
 Compound Info 
4-(methylamino)-2-[4-methyl-3-(prop-2-enoylamino)anilino]-N-[2-methyl-5-[(3,4,5-trimethoxybenzoyl)amino]phenyl]pyrimidine-5-carboxamide
   Show/Hide
 C33H35N7O6  1
1
GI50 = 7890 nM
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CP0231885
 Compound Info 
1-[(2R,4S,5S)-5-[[tert-butyl(dimethyl)silyl]oxymethyl]-4-[2-(3,4-dimethoxyphenyl)-1,3-dithian-2-yl]oxolan-2-yl]-5-methylpyrimidine-2,4-dione
   Show/Hide
 C28H42N2O6S2Si  1
1
GI50 = 3720 nM
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CP0247307
 Compound Info 
(2E)-3-{4-[3-(adamantan-1-yl)-4-acetamidophenyl]-3-chlorophenyl}prop-2-enoic acid
   Show/Hide
 C27H28ClNO3  1
1
IC50 = 5000 nM
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CP0247982
 Compound Info 
(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2R)-2-acetamido-4-methylpentanoyl]amino]-4-methylpentanoyl]amino]-4-methylpentanoyl]amino]-4-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-3-methylbutanoyl]amino]-6-amino-N-[(4-carbamimidoylphenyl)methyl]hexanamide
   Show/Hide
 C51H90N14O8  1
1
IC50 = 25000 nM
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CP0253982
 Compound Info 
8-[4-[6-[(2-bromophenyl)-ethylsulfamoyl]-3-(4-hydroxyphenyl)-7-oxabicyclo[2.2.1]hept-2-en-2-yl]anilino]-8-oxooctanoic acid
   Show/Hide
 C34H37BrN2O7S  1
1
IC50 = 95300 nM
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CP0267543
 Compound Info 
5-(2,5-Dihydroxy-benzylamino)-N-hexyl-2-hydroxy-benzamide
   Show/Hide
 C20H26N2O4  1
1
GI50 = 15000 nM
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CP0268441
 Compound Info 
5-(2,5-Dihydroxy-benzylamino)-N-[2-(4-fluoro-phenyl)-ethyl]-2-hydroxy-benzamide
   Show/Hide
 C22H21FN2O4  1
1
GI50 = 18000 nM
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CP0304095
 Compound Info 
8-[4-[[(19S)-10,19-diethyl-19-hydroxy-14,18-dioxo-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4(9),5,7,10,15(20)-heptaen-7-yl]oxymethyl]triazol-1-yl]-N-hydroxyoctanamide
   Show/Hide
 C33H38N6O7  1
1
IC50 = 3510 nM
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CP0304520
 Compound Info 
8-[4-[6-(4-fluorophenoxy)sulfonyl-3-(4-hydroxyphenyl)-7-oxabicyclo[2.2.1]hept-2-en-2-yl]anilino]-8-oxooctanoic acid
   Show/Hide
 C32H32FNO8S  1
1
IC50 > 100000 nM
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CP0320349
 Compound Info 
N-benzyl-5-[(2,5-dihydroxyphenyl)methylamino]-2-hydroxybenzamide
   Show/Hide
 C21H20N2O4  1
1
GI50 = 16000 nM
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CP0327530
 Compound Info 
[(4aR,8aS)-4-(4-amino-6,7-dimethoxyquinazolin-2-yl)-2,3,4a,5,6,7,8,8a-octahydroquinoxalin-1-yl]-(2,3-dihydro-1,4-benzodioxin-3-yl)methanone
   Show/Hide
 C27H31N5O5  1
1
EC50 = 2600 nM
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CP0336278
 Compound Info 
7-[4-[[(19S)-19-ethyl-19-hydroxy-14,18-dioxo-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2(11),3,5,7,9,15(20)-heptaen-7-yl]oxymethyl]triazol-1-yl]-N-hydroxyheptanamide
   Show/Hide
 C30H32N6O7  1
1
IC50 = 2030 nM
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CP0345034
 Compound Info 
[(2R)-1-(4-tert-butylphenoxy)-3-(2-nitroimidazol-1-yl)propan-2-yl] 4-[(2-hydroxy-5-oxocyclopenta-1,3-dien-1-yl)methylideneamino]benzoate
   Show/Hide
 C29H28N4O7  1
1
LC50 = 63000 nM
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CP0358636
 Compound Info 
N-[2-(4-chlorophenyl)ethyl]-5-[(2,5-dihydroxyphenyl)methylamino]-2-hydroxybenzamide
   Show/Hide
 C22H21ClN2O4  1
1
GI50 = 16000 nM
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CP0373216
 Compound Info 
(2E)-3-{3-chloro-4-[4-hydroxy-3-(1-methylcyclohexyl)phenyl]phenyl}prop-2-enoic acid
   Show/Hide
 C22H23ClO3  1
1
IC50 = 8000 nM
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CP0378571
 Compound Info 
methyl 2-[2-[5-(dimethylamino)pentyl-methylamino]-3-(4-phenylphenyl)-4H-quinazolin-4-yl]acetate
   Show/Hide
 C31H38N4O2  1
1
GI50 = 1780 nM
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CP0380904
 Compound Info 
6-(5-Chloro-2-methoxy-phenyl)-N*2*-(4-chloro-phenyl)-pyrimidine-2,4-diamine
   Show/Hide
 C17H14Cl2N4O  1
1
IC50 > 10000 nM
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CP0382386
 Compound Info 
3-methoxy-6-[[(E)-2-(2,4,6-trimethoxyphenyl)ethenyl]sulfonylmethyl]pyridin-2-amine
   Show/Hide
 C18H22N2O6S  1
1
GI50 = 6 nM
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CP0383276
 Compound Info 
N-(4-methoxyphenyl)-N,2,6-trimethylfuro[2,3-d]pyrimidin-4-amine
   Show/Hide
 C16H17N3O2  1
1
GI50 = 26.2 nM
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CP0383413
 Compound Info 
N-[2-methyl-5-(2-oxo-9-pyrazol-1-ylbenzo[h][1,6]naphthyridin-1-yl)phenyl]prop-2-enamide
   Show/Hide
 C25H19N5O2  1
1
GI50 > 10000 nM
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CP0386600
 Compound Info 
(E)-1-(5-bromo-2-hydroxyphenyl)-3-(2-propan-2-yloxyphenyl)prop-2-en-1-one
   Show/Hide
 C18H17BrO3  1
1
IC50 = 5030 nM
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CP0387728
 Compound Info 
6-[4-[[(19S)-10,19-diethyl-19-hydroxy-14,18-dioxo-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4(9),5,7,10,15(20)-heptaen-7-yl]oxymethyl]triazol-1-yl]-N-hydroxyhexanamide
   Show/Hide
 C31H34N6O7  1
1
IC50 = 2050 nM
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CP0390395
 Compound Info 
2-(2-(dimethylamino)-3-phenyl-3,4-dihydroquinazolin-4-yl)-N-(4-nitrobenzyl)acetamide
   Show/Hide
 C25H25N5O3  1
1
GI50 > 100000 nM
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CP0392856
 Compound Info 
(E)-3-(2,3-dimethoxyphenyl)-1-[5-[(E)-3-(2,3-dimethoxyphenyl)prop-2-enoyl]-2,4-dihydroxyphenyl]prop-2-en-1-one
   Show/Hide
 C28H26O8  1
1
EC50 = 2450 nM
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CP0393427
 Compound Info 
(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2R)-2-acetamido-4-methylpentanoyl]amino]-4-methylpentanoyl]amino]-4-methylpentanoyl]amino]-4-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-3-methylbutanoyl]amino]-6-amino-N-[(2S)-1-[[(2S)-1-[[(2S)-3-(4-carbamimidoylphenyl)-1-[2-(1H-indol-3-yl)ethylamino]-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]hexanamide
   Show/Hide
 C72H119N21O11  1
1
IC50 = 28000 nM
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CP0393431
 Compound Info 
(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-acetamido-4-methylpentanoyl]amino]-4-methylpentanoyl]amino]-4-methylpentanoyl]amino]-4-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-3-methylbutanoyl]amino]-6-amino-N-[(2S)-1-[[(2S)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]hexanamide
   Show/Hide
 C60H104N18O10  1
1
IC50 = 25000 nM
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CP0397786
 Compound Info 
N-[[4-[(4-fluorophenyl)sulfonylamino]phenyl]methyl]-2-(3-phenyl-2-piperidin-1-yl-4H-quinazolin-4-yl)acetamide
   Show/Hide
 C34H34FN5O3S  1
1
GI50 = 1710 nM
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CP0403197
 Compound Info 
(2S)-N-[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2R)-6-amino-1-[[(2S)-1-[[(2S)-1-[(2S)-2-[(2-amino-2-oxoethyl)carbamoyl]pyrrolidin-1-yl]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-1-oxohexan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]-5-oxopyrrolidine-2-carboxamide
   Show/Hide
 C59H84N18O13  1
1
IC50 > 40000 nM
   TI
   LI
   LO
   TS
CP0404158
 Compound Info 
2-(5-Chloro-2-methoxy-phenyl)-N-(4-chloro-phenyl)-pyrimidine-4,6-diamine
   Show/Hide
 C17H14Cl2N4O  1
1
IC50 = 5000 nM
   TI
   LI
   LO
   TS
CP0405350
 Compound Info 
N-[4-[2-[(2S,3S,5R)-2-[[tert-butyl(dimethyl)silyl]oxymethyl]-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-3-yl]-1,3-dithian-2-yl]phenyl]-N'-hydroxyhexanediamide
   Show/Hide
 C32H48N4O7S2Si  1
1
GI50 = 14800 nM
   TI
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   TS
CP0407311
 Compound Info 
1-cyano-2-[6-[cyclohexyl(2-morpholin-4-ylethoxy)sulfamoyl]hexyl]-3-pyridin-4-ylguanidine
   Show/Hide
 C25H41N7O4S  1
1
IC50 > 50 nM
   TI
   LI
   LO
   TS
CP0408582
 Compound Info 
1-[3-[4-[1-adamantyl(phenyl)methyl]phenyl]propyl]piperazine
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 C30H40N2  1
1
LC50 = 8.46 nM
   TI
   LI
   LO
   TS
CP0409565
 Compound Info 
3-[(Z)-dec-1-enyl]-2,4,6-trimethylpyridine
   Show/Hide
 C18H29N  1
1
ED50 > 30000 nM
   TI
   LI
   LO
   TS
CP0410128
 Compound Info 
4-[2-Amino-6-(5-bromo-2-ethoxy-phenyl)-pyrimidin-4-ylamino]-N-hydroxy-benzamide
   Show/Hide
 C19H18BrN5O3  1
1
IC50 > 1000 nM
   TI
   LI
   LO
   TS
CP0410878
 Compound Info 
5,5-dimethyl-1,3-bis[3-(trifluoromethyl)phenyl]imidazolidine-2,4-dione
   Show/Hide
 C19H14F6N2O2  1
1
IC50 = 100000 nM
   TI
   LI
   LO
   TS
CP0410880
 Compound Info 
2-hydroxy-2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]-3-[4-(trifluoromethoxy)phenoxy]propanamide
   Show/Hide
 C18H14F6N2O6  1
1
IC50 = 10430 nM
   TI
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   TS
CP0410891
 Compound Info 
5,5-dimethyl-1-[4-nitro-2-(trifluoromethyl)phenyl]-3-[3-(trifluoromethyl)phenyl]imidazolidine-2,4-dione
   Show/Hide
 C19H13F6N3O4  1
1
IC50 = 7880 nM
   TI
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   TS
CP0412412
 Compound Info 
2-[[(3S)-1-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperidin-3-yl]amino]naphthalene-1,4-dione
   Show/Hide
 C25H25N5O4  1
1
IC50 = 18540 nM
   TI
   LI
   LO
   TS
CP0412979
 Compound Info 
N-[4-[2-fluoro-4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]phenyl]-2-(4-methylsulfonylphenyl)acetamide
   Show/Hide
 C24H18F7NO4S  1
1
IC50 = 41230 nM
   TI
   LI
   LO
   TS
CP0414228
 Compound Info 
N-[(6,6-diphenyl-1,4-dioxan-2-yl)methyl]-2-(2-methoxyphenoxy)ethanamine
   Show/Hide
 C26H29NO4  1
1
GI50 = 23000 nM
   TI
   LI
   LO
   TS
CP0415532
 Compound Info 
(E)-1-(2-hydroxy-5-methoxyphenyl)-3-(2-methoxyphenyl)prop-2-en-1-one
   Show/Hide
 C17H16O4  1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0417525
 Compound Info 
(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S,3R)-2-acetamido-3-hydroxybutanoyl]amino]-4-methylpentanoyl]amino]-4-methylpentanoyl]amino]-4-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-3-methylbutanoyl]amino]-6-amino-N-[(4-carbamimidoylphenyl)methyl]hexanamide
   Show/Hide
 C49H86N14O9  1
1
IC50 = 140000 nM
   TI
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   TS
CP0421176
 Compound Info 
tert-butyl N-[5-[4-[2-(benzylamino)-2-oxoethyl]-2-(4-phenylanilino)-4H-quinazolin-3-yl]pentyl]carbamate
   Show/Hide
 C39H45N5O3  1
1
GI50 = 1790 nM
   TI
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   TS
CP0421570
 Compound Info 
N-(5-methoxynaphthalen-2-yl)-N,2-dimethyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-amine
   Show/Hide
 C20H21N3O  1
1
GI50 < 10 nM
   TI
   LI
   LO
   TS
CP0424050
 Compound Info 
3,5-bis[(Z)-dec-1-enyl]-2,4,6-trimethylpyridine
   Show/Hide
 C28H47N  1
1
ED50 > 30000 nM
   TI
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   TS
CP0425261
 Compound Info 
N-(1-benzofuran-5-yl)-N,2,6-trimethylfuro[2,3-d]pyrimidin-4-amine
   Show/Hide
 C17H15N3O2  1
1
GI50 = 198 nM
   TI
   LI
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   TS
CP0425306
 Compound Info 
6-(5-Chloro-2-ethoxy-phenyl)-N*4*-(3-nitro-phenyl)-pyrimidine-2,4-diamine
   Show/Hide
 C18H16ClN5O3  1
1
IC50 > 1000 nM
   TI
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   LO
   TS
CP0426667
 Compound Info 
1-[[(2R)-3,3-diphenyl-1,4-dioxan-2-yl]methyl]-4-(2-methoxyphenyl)piperazine
   Show/Hide
 C28H32N2O3  1
1
GI50 = 35000 nM
   TI
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   LO
   TS
CP0430530
 Compound Info 
4-N-(4-chlorophenyl)-6-(2,5-dichlorophenyl)pyrimidine-2,4-diamine
   Show/Hide
 C16H11Cl3N4  1
1
IC50 = 190 nM
   TI
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   TS
CP0431818
 Compound Info 
(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2R)-2-acetamido-4-methylpentanoyl]amino]-4-methylpentanoyl]amino]-4-methylpentanoyl]amino]-4-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-3-methylbutanoyl]amino]-6-amino-N-[(2S)-1-[[(2S)-1-[[(1S)-1-(4-carbamimidoylphenyl)-2-[2-(1H-indol-3-yl)ethylamino]-2-oxoethyl]amino]-1-oxopropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]hexanamide
   Show/Hide
 C71H117N21O11  1
1
IC50 = 40000 nM
   TI
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   TS
CP0431877
 Compound Info 
(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-acetamido-4-methylpentanoyl]amino]-4-methylpentanoyl]amino]-4-methylpentanoyl]amino]-4-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-3-methylbutanoyl]amino]-6-amino-N-[(2S)-1-[[(2S)-1-amino-4-methyl-1-oxopentan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]hexanamide
   Show/Hide
 C55H105N17O10  1
1
IC50 = 90000 nM
   TI
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   TS
CP0432230
 Compound Info 
N-(2,3-dihydro-1-benzofuran-5-yl)-N,2,6-trimethylfuro[2,3-d]pyrimidin-4-amine
   Show/Hide
 C17H17N3O2  1
1
GI50 = 44.1 nM
   TI
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   TS
CP0435180
 Compound Info 
2-hydroxy-2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]-3-[3-(pentafluoro-lambda6-sulfanyl)phenoxy]propanamide
   Show/Hide
 C17H14F8N2O5S  1
1
IC50 = 7400 nM
   TI
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   TS
CP0438412
 Compound Info 
prop-2-ynyl N-[4-chloro-3-(5-chloro-1,3-benzoxazol-2-yl)phenyl]carbamate
   Show/Hide
 C17H10Cl2N2O3  1
1
IC50 = 50000 nM
   TI
   LI
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   TS
CP0443638
 Compound Info 
3,5-bis[(Z)-dec-1-enyl]-2-(3-methoxypropyl)-4,6-dimethylpyridine
   Show/Hide
 C31H53NO  1
1
ED50 > 30000 nM
   TI
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   TS
CP0447500
 Compound Info 
4-(3-oxo-1-sulfanylidene-3a,4-dihydroimidazo[1,5-a]indol-2-yl)-2-(trifluoromethyl)benzonitrile
   Show/Hide
 C18H10F3N3OS  1
1
IC50 = 143100 nM
   TI
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   TS
CP0449284
 Compound Info 
4-methyl-7-(2-methylphenyl)-6-pentylpurino[7,8-a]imidazole-1,3-dione
   Show/Hide
 C20H23N5O2  1
1
IC50 = 6970 nM
   TI
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   LO
   TS
CP0449938
 Compound Info 
1-[3-[4-[1-adamantyl(phenyl)methyl]phenyl]propyl]piperidine
   Show/Hide
 C31H41N  1
1
GI50 = 5.18 nM
   TI
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   TS
CP0452777
 Compound Info 
1-[3-[4-[1-adamantyl(phenyl)methyl]phenyl]propyl]-4-methylpiperazine
   Show/Hide
 C31H42N2  1
1
GI50 = 3.77 nM
   TI
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CP0455486
 Compound Info 
(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-acetamido-4-methylpentanoyl]amino]-4-methylpentanoyl]amino]-4-methylpentanoyl]amino]-4-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-3-methylbutanoyl]amino]-6-amino-N-[(2S)-1-[[(2S)-1-amino-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]hexanamide
   Show/Hide
 C55H106N20O10  1
1
IC50 = 71000 nM
   TI
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   TS
CP0455763
 Compound Info 
(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-acetamido-4-methylpentanoyl]amino]-4-methylpentanoyl]amino]-4-methylpentanoyl]amino]-4-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-3-methylbutanoyl]amino]-6-amino-N-[(2S)-1-[[(2S)-1-amino-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]hexanamide
   Show/Hide
 C58H103N17O11  1
1
IC50 = 100000 nM
   TI
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   TS
CP0457111
 Compound Info 
prop-2-ynyl N-[4-chloro-3-(5-chloro-1,3-benzothiazol-2-yl)phenyl]carbamate
   Show/Hide
 C17H10Cl2N2O2S  1
1
IC50 > 50000 nM
   TI
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   TS
CP0461401
 Compound Info 
2-(2-(dimethylamino)-3-phenyl-3,4-dihydroquinazolin-4-yl)-N-(4-(4-methylphenylsulfonamido)benzyl)acetamide
   Show/Hide
 C32H33N5O3S  1
1
GI50 = 6520 nM
   TI
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   TS
CP0462127
 Compound Info 
(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-acetamido-4-methylpentanoyl]amino]-4-methylpentanoyl]amino]-4-methylpentanoyl]amino]-4-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-3-methylbutanoyl]amino]-6-aminohexanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]pentanediamide
   Show/Hide
 C54H102N18O11  1
1
IC50 = 210000 nM
   TI
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   TS
CP0465259
 Compound Info 
(2S)-6-amino-N-[(2S)-1-amino-5-(diaminomethylideneamino)-1-oxopentan-2-yl]-2-[[(2S)-2-[[(2S)-5-(diaminomethylideneamino)-2-[[(2S)-4-methyl-2-[[(2S)-4-methyl-2-[[(2S)-4-methyl-2-[[(2S)-4-methyl-2-(9-oxodecylamino)pentanoyl]amino]pentanoyl]amino]pentanoyl]amino]pentanoyl]amino]pentanoyl]amino]-3-methylbutanoyl]amino]hexanamide
   Show/Hide
 C57H110N16O9  1
1
IC50 = 80000 nM
   TI
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   TS
CP0467732
 Compound Info 
(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-acetamido-4-methylpentanoyl]amino]-4-methylpentanoyl]amino]-4-methylpentanoyl]amino]-4-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-3-methylbutanoyl]amino]-6-amino-N-[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]hexanamide
   Show/Hide
 C58H103N17O10  1
1
IC50 = 70000 nM
   TI
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   TS
CP0468875
 Compound Info 
(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S,3S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-acetamido-4-methylpentanoyl]amino]-4-methylpentanoyl]amino]-3-methylpentanoyl]amino]-3-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-3-methylbutanoyl]amino]-6-amino-N-[(4-carbamimidoylphenyl)methyl]hexanamide
   Show/Hide
 C51H90N14O8  1
1
IC50 = 20000 nM
   TI
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   LO
   TS
CP0471493
 Compound Info 
(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-acetamido-4-methylpentanoyl]amino]-4-methylpentanoyl]amino]-4-methylpentanoyl]amino]-4-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-3-methylbutanoyl]amino]-6-amino-N-[(2S)-1-[[(2S)-1-amino-3-hydroxy-1-oxopropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]hexanamide
   Show/Hide
 C52H99N17O11  1
1
IC50 = 240000 nM
   TI
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   LO
   TS
CP0471494
 Compound Info 
(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-acetamido-4-methylpentanoyl]amino]-4-methylpentanoyl]amino]-4-methylpentanoyl]amino]-4-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-3-methylbutanoyl]amino]-6-amino-N-[(2S)-1-[[(2S)-1-amino-1-oxopropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]hexanamide
   Show/Hide
 C52H99N17O10  1
1
IC50 = 160000 nM
   TI
   LI
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   TS
CP0471498
 Compound Info 
(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-acetamido-4-methylpentanoyl]amino]-4-methylpentanoyl]amino]-4-methylpentanoyl]amino]-4-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-3-methylbutanoyl]amino]-6-amino-N-[(2S)-1-[[(2S,3R)-1-amino-3-hydroxy-1-oxobutan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]hexanamide
   Show/Hide
 C53H101N17O11  1
1
IC50 = 170000 nM
   TI
   LI
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   TS
CP0471655
 Compound Info 
(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-acetamido-3-(1H-indol-3-yl)propanoyl]amino]-4-methylpentanoyl]amino]-4-methylpentanoyl]amino]-4-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-3-methylbutanoyl]amino]-6-amino-N-[(4-carbamimidoylphenyl)methyl]hexanamide
   Show/Hide
 C56H89N15O8  1
1
IC50 = 23000 nM
   TI
   LI
   LO
   TS
CP0472045
 Compound Info 
(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2R)-2-acetamido-4-methylpentanoyl]amino]-4-methylpentanoyl]amino]-4-methylpentanoyl]amino]-4-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-3-methylbutanoyl]amino]-6-amino-N-[(2S)-1-[2-(4-carbamimidoylphenyl)ethylamino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]hexanamide
   Show/Hide
 C58H104N18O9  1
1
IC50 = 41000 nM
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   LO
   TS
CP0475175
 Compound Info 
(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-acetamido-4-methylpentanoyl]amino]-4-methylpentanoyl]amino]-4-methylpentanoyl]amino]-N-[(2S)-1-[[(2S)-1-[[(2S)-6-amino-1-[(4-carbamimidoylphenyl)methylamino]-1-oxohexan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]pentanediamide
   Show/Hide
 C50H87N15O9  1
1
IC50 = 12000 nM
   TI
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   TS
CP0475184
 Compound Info 
(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-acetamido-3-hydroxypropanoyl]amino]-4-methylpentanoyl]amino]-4-methylpentanoyl]amino]-4-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-3-methylbutanoyl]amino]-6-amino-N-[(4-carbamimidoylphenyl)methyl]hexanamide
   Show/Hide
 C48H84N14O9  1
1
IC50 = 100000 nM
   TI
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   LO
   TS
CP0478975
 Compound Info 
(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-acetamido-4-methylpentanoyl]amino]-4-methylpentanoyl]amino]-4-methylpentanoyl]amino]-4-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-3-methylbutanoyl]amino]-6-amino-N-[(2S)-1-[[(2S)-1-amino-3-methyl-1-oxobutan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]hexanamide
   Show/Hide
 C54H103N17O10  1
1
IC50 = 170000 nM
   TI
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   TS
CP0482950
 Compound Info 
2-hydroxy-2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]-3-[3-(trifluoromethoxy)phenoxy]propanamide
   Show/Hide
 C18H14F6N2O6  1
1
IC50 = 13140 nM
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   TS
CP0484329
 Compound Info 
(3S)-3-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-acetamido-4-methylpentanoyl]amino]-4-methylpentanoyl]amino]-4-methylpentanoyl]amino]-4-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-3-methylbutanoyl]amino]-6-aminohexanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-4-amino-4-oxobutanoic acid
   Show/Hide
 C53H99N17O12  1
1
IC50 = 230000 nM
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   TS
CP0488255
 Compound Info 
5,5-dimethyl-1-[4-nitro-3-(trifluoromethyl)phenyl]-3-[4-(trifluoromethyl)phenyl]imidazolidine-2,4-dione
   Show/Hide
 C19H13F6N3O4  1
1
IC50 >= 100000 nM
   TI
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   TS
CP0492495
 Compound Info 
6-(5-Chloro-2-methyl-phenyl)-N*4*-(4-trifluoromethyl-phenyl)-pyrimidine-2,4-diamine
   Show/Hide
 C18H14ClF3N4  1
1
IC50 = 230 nM
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   TS
CP0495053
 Compound Info 
4-N-(4-bromophenyl)-6-(5-chloro-2-methoxyphenyl)pyrimidine-2,4-diamine
   Show/Hide
 C17H14BrClN4O  1
1
IC50 = 250 nM
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CP0495619
 Compound Info 
(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-acetamido-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]-4-methylpentanoyl]amino]-4-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-3-methylbutanoyl]amino]-6-amino-N-[(4-carbamimidoylphenyl)methyl]hexanamide
   Show/Hide
 C54H88N14O8  1
1
IC50 = 30000 nM
   TI
   LI
   LO
   TS
CP0496434
 Compound Info 
[(4aS,8aS)-4-(4-amino-6,7-dimethoxyquinazolin-2-yl)-2,3,4a,5,6,7,8,8a-octahydroquinoxalin-1-yl]-(2,3-dihydro-1,4-benzodioxin-3-yl)methanone
   Show/Hide
 C27H31N5O5  1
1
IC50 > 10000 nM
   TI
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CP0496891
 Compound Info 
1-{4-[(3-chlorophenyl)amino-6-quinazolinyl}-3-(2-N,N-dimethylaminoethyl)triazene
   Show/Hide
 C18H20ClN7  1
1
IC50 = 37230 nM
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CP0497857
 Compound Info 
N-[(4-aminophenyl)methyl]-2-[2-(dimethylamino)-3-phenyl-4H-quinazolin-4-yl]acetamide
   Show/Hide
 C25H27N5O  1
1
GI50 > 100000 nM
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CP0499759
 Compound Info 
2-[2-[2-[2-[2-[2-[2-[2-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-6-amino-1-[[(2S)-1-amino-5-carbamimidamido-1-oxopentan-2-yl]amino]-1-oxohexan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethyl acetate
   Show/Hide
 C65H126N16O17  1
1
IC50 = 500000 nM
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CP0500230
 Compound Info 
1-[[4-[1-adamantyl(phenyl)methyl]phenyl]methyl]-4-methylpiperazine
   Show/Hide
 C29H38N2  1
1
GI50 = 3.01 nM
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CP0502814
 Compound Info 
4-N-(4-bromophenyl)-2-(5-chloro-2-methoxyphenyl)pyrimidine-4,6-diamine
   Show/Hide
 C17H14BrClN4O  1
1
IC50 = 800 nM
   TI
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   TS
CP0503035
 Compound Info 
(2E)-3-[3-chloro-4-(4-hydroxy-3-{tricyclo[3.3.1.0^{3,7}]nonan-3-yl}phenyl)phenyl]prop-2-enoic acid
   Show/Hide
 C24H23ClO3  1
1
IC50 = 7900 nM
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CP0504395
 Compound Info 
tert-butyl N-[5-[[4-[2-(benzylamino)-2-oxoethyl]-3-phenyl-1,4-dihydroquinazolin-2-ylidene]amino]pentyl]carbamate
   Show/Hide
 C33H41N5O3  1
1
GI50 = 4260 nM
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CP0507396
 Compound Info 
8-[4-[3-(4-hydroxyphenyl)-6-[(4-methoxyphenyl)-methylsulfamoyl]-7-oxabicyclo[2.2.1]hept-2-en-2-yl]anilino]-8-oxooctanoic acid
   Show/Hide
 C34H38N2O8S  1
1
IC50 = 67100 nM
   TI
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   TS
CP0508138
 Compound Info 
3-(4-cyanophenoxy)-N-[4-cyano-3-(trifluoromethyl)phenyl]-2-hydroxy-2-methylpropanamide
   Show/Hide
 C19H14F3N3O3  1
1
IC50 = 44600 nM
   TI
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CP0510899
 Compound Info 
1-{4-[(3-chlorophenyl)amino-6-quinazolinyl}-3-{2-[N-(2-chloroethyl)-N-4-methoxyphenylethylenamine]} triazene
   Show/Hide
 C25H25Cl2N7O  1
1
IC50 = 7950 nM
   TI
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   TS
CP0517983
 Compound Info 
N-[4-[2-[(2S,3S,5S)-2-[[tert-butyl(dimethyl)silyl]oxymethyl]-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-3-yl]-1,3-dithian-2-yl]phenyl]-N'-hydroxyoctanediamide
   Show/Hide
 C34H52N4O7S2Si  2
1
GI50 = 3980 nM
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2
GI50 = 3981.07 nM
   TI
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CP0518082
 Compound Info 
6-(5-Chloro-2-ethoxy-phenyl)-N*4*-(1H-indazol-6-yl)-pyrimidine-2,4-diamine
   Show/Hide
 C19H17ClN6O  1
1
IC50 = 200 nM
   TI
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   TS
CP0520200
 Compound Info 
6-(5-Chloro-2-methoxy-phenyl)-N*2*-(1H-indazol-6-yl)-pyrimidine-2,4-diamine
   Show/Hide
 C18H15ClN6O  1
1
IC50 > 10000 nM
   TI
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CP0520322
 Compound Info 
6-(5-Bromo-2-ethoxy-phenyl)-N*4*-(4-dihydroxyboron-phenyl)-pyrimidine-2,4-diamine
   Show/Hide
 C18H18BBrN4O3  1
1
IC50 = 500 nM
   TI
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CP0524982
 Compound Info 
1-[4-[1-adamantyl(phenyl)methyl]phenyl]-4-methylpiperazine
   Show/Hide
 C28H36N2  1
1
GI50 = 6430 nM
   TI
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   TS
CP0526919
 Compound Info 
(2E)-3-{3-chloro-4-[4-hydroxy-3-(2-methyl-1,3-dithian-2-yl)phenyl]phenyl}prop-2-enoic acid
   Show/Hide
 C20H19ClO3S2  1
1
IC50 > 20000 nM
   TI
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CP0530109
 Compound Info 
4-[2-Amino-6-(5-bromo-2-ethoxy-phenyl)-pyrimidin-4-ylamino]-benzonitrile
   Show/Hide
 C19H16BrN5O  1
1
IC50 = 400 nM
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CP0530111
 Compound Info 
1-{4-[2-Amino-6-(5-bromo-2-ethoxy-phenyl)-pyrimidin-4-ylamino]-phenyl}-ethanone O-methyl-oxime
   Show/Hide
 C21H22BrN5O2  1
1
IC50 > 1000 nM
   TI
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CP0530725
 Compound Info 
(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-acetamido-4-methylpentanoyl]amino]-4-methylpentanoyl]amino]-4-methylpentanoyl]amino]-4-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-3-methylbutanoyl]amino]-6-amino-N-[(2S)-1-[[(2S)-1-amino-3-(4-aminophenyl)-1-oxopropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]hexanamide
   Show/Hide
 C58H104N18O10  1
1
IC50 = 139000 nM
   TI
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CP0531427
 Compound Info 
1-{4-[2-Amino-6-(5-bromo-2-ethoxy-phenyl)-pyrimidin-4-ylamino]-phenyl}-ethanone
   Show/Hide
 C20H19BrN4O2  1
1
IC50 = 90 nM
   TI
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CP0533537
 Compound Info 
[(2R,3R,5R)-5-(4-amino-2-oxopyrimidin-1-yl)-4,4-difluoro-3-hydroxyoxolan-2-yl]methyl N-[(5R)-6-[[(2S)-1-[[(2S)-1-[(2S)-2-[(2-amino-2-oxoethyl)carbamoyl]pyrrolidin-1-yl]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-5-[[(2S)-2-[[(2S)-3-hydroxy-2-[[(2S)-2-[[(2S)-3-(1H-imidazol-5-yl)-2-[[(2S)-5-oxopyrrolidine-2-carbonyl]amino]propanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]propanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-6-oxohexyl]carbamate
   Show/Hide
 C69H93F2N21O18  1
1
IC50 > 40000 nM
   TI
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CP0534514
 Compound Info 
6-(5-Chloro-2-methoxy-phenyl)-N*4*-(1H-indazol-6-yl)-pyrimidine-2,4-diamine
   Show/Hide
 C18H15ClN6O  1
1
IC50 = 1000 nM
   TI
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   TS
CP0534872
 Compound Info 
4-N-(4-bromophenyl)-6-(5-chloro-2-methylphenyl)pyrimidine-2,4-diamine
   Show/Hide
 C17H14BrClN4  1
1
IC50 = 130 nM
   TI
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   TS
CP0538748
 Compound Info 
6-(5-Chloro-2-methyl-phenyl)-N*4*-(4-chloro-phenyl)-pyrimidine-2,4-diamine
   Show/Hide
 C17H14Cl2N4  1
1
IC50 = 120 nM
   TI
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CP0542856
 Compound Info 
1-{4-[(3-chlorophenyl)amino-6-quinazolinyl}-3-{2-[N-(2-chloroethyl)-N-benzylethylenamine]}triazene
   Show/Hide
 C25H25Cl2N7  1
1
IC50 = 10550 nM
   TI
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CP0544976
 Compound Info 
4-N-(3-bromophenyl)-6-(5-chloro-2-methylphenyl)pyrimidine-2,4-diamine
   Show/Hide
 C17H14BrClN4  1
1
IC50 = 400 nM
   TI
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   TS
CP0548921
 Compound Info 
(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-acetamido-4-methylpentanoyl]amino]-4-methylpentanoyl]amino]-3-methylpentanoyl]amino]-4-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-3-methylbutanoyl]amino]-6-amino-N-[(4-carbamimidoylphenyl)methyl]hexanamide
   Show/Hide
 C51H90N14O8  1
1
IC50 = 32000 nM
   TI
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CP0558284
 Compound Info 
(1S,7R,10S,16E,21R)-7-(2-methylpropyl)-21-propan-2-yl-2-oxa-12,13-dithia-5,8,20,23-tetrazabicyclo[8.7.6]tricos-16-ene-3,6,9,19,22-pentone
   Show/Hide
 C23H36N4O6S2  1
1
GI50 = 37 nM
   TI
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CP0573211
 Compound Info 
2-N-(4-bromophenyl)-6-(5-chloro-2-methoxyphenyl)pyrimidine-2,4-diamine
   Show/Hide
 C17H14BrClN4O  1
1
IC50 > 10000 nM
   TI
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CP0659163
 Compound Info 
(exo)-5,6-bis(4-hydroxyphenyl)-7-oxabicyclo[2.2.1]hept-5-ene-2-sulfonic acid phenyl ester
   Show/Hide
 C24H20O6S  1
1
IC50 > 100000 nM
   TI
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CP0689907
 Compound Info 
(exo-rac)-8-(4-(3-(4-Hydroxyphenyl)-6-(phenoxysulfonyl)-7-oxabicyclo-[2.2.1]hept-2-en-2-yl)phenylamino)-8-oxooctanoic Acid
   Show/Hide
 C32H33NO8S  1
1
IC50 > 100000 nM
   TI
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CP0708265
 Compound Info 
Methyl 8-(4-(5,6-Bis(4-hydroxyphenyl)-7-oxabicyclo[2.2.1]hept-5-en-2-yl-sulfonyloxy)phenylamino)-8-oxooctanoate
   Show/Hide
 C33H35NO9S  1
1
IC50 = 20400 nM
   TI
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CP0751777
 Compound Info 
Anibamine
   Show/Hide
 C32H50F3NO2  2
1
ED50 = 1000 nM
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2
ED50 = 1020 nM
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CP0863685
 Compound Info 
8-((E)-dec-1-enyl)-6-((Z)-dec-1-enyl)-5,7-dimethyl-2,3-dihydro-1H-indolizinium chloride
   Show/Hide
 C30H50ClN  1
1
ED50 = 200 nM
   TI
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CP0863686
 Compound Info 
1,3-di((Z)-dec-1-enyl)-2,4-dimethyl-7,8,9,10-tetrahydro-6H-pyrido[1,2-a]azepinium chloride
   Show/Hide
 C32H54ClN  1
1
ED50 = 800 nM
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CP0880819
 Compound Info 
8-Dec-1-(Z)-enyl-5,7-dimethyl-2,3-dihydro-1H-indolizinium chloride
   Show/Hide
 C20H32ClN  1
1
ED50 = 200 nM
   TI
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CP0882086
 Compound Info 
6-Dec-1-(Z)-enyl-5,7-dimethyl-2,3-dihydro-1H-indolizinium chloride
   Show/Hide
 C20H32ClN  1
1
ED50 = 900 nM
   TI
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CP0882087
 Compound Info 
6,8-di((E)-dec-1-enyl)-5,7-dimethyl-2,3-dihydro-1H-indolizinium chloride
   Show/Hide
 C30H50ClN  1
1
ED50 = 800 nM
   TI
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CP0882142
 Compound Info 
6,8-Didecyl-5,7-dimethyl-2,3-dihydro-1H-indolizinium chloride
   Show/Hide
 C30H54ClN  1
1
ED50 = 1300 nM
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CP0897293
 Compound Info 
1-(7-Benzyl-2-methyl-5H-pyrrolo[3,2-d]pyrimidin-4-yl)-6-methoxy-1,2,3,4-tetrahydroquinoline hydrochloride
   Show/Hide
 C24H25ClN4O  1
1
GI50 = 383 nM
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CP0906523
 Compound Info 
7-Benzyl-N-(4-methoxyphenyl)-N,2,5-trimethyl-5H-pyrrolo[3,2-d]pyrimidin-4-amine hydrochloride
   Show/Hide
 C23H25ClN4O  1
1
GI50 = 44.4 nM
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CP0913385
 Compound Info 
6-Dec-1-(E)-enyl-5,7-dimethyl-2,3-dihydro-1Hindolizinium chloride
   Show/Hide
 C20H32ClN  1
1
ED50 = 800 nM
   TI
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CP0913386
 Compound Info 
8-Dec-1-(E)-enyl-5,7-dimethyl-2,3-dihydro-1Hindolizinium chloride
   Show/Hide
 C20H32ClN  1
1
ED50 = 600 nM
   TI
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CP0914655
 Compound Info 
(E)-1-[5-Acetyl-2,4-dihydroxyphenyl]-3-(benzo[d][1,3]dioxol-5-yl)prop-2-en-1-one
   Show/Hide
 C18H14O6  1
1
EC50 = 16320 nM
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CP0915191
 Compound Info 
7,9-di((E)-dec-1-enyl)-6,8-dimethyl-1,2,3,4-tetrahydroquinolizinium 2,2,2-trifluoroacetate
   Show/Hide
 C33H52F3NO2  1
1
ED50 = 460 nM
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CP0916822
 Compound Info 
1-{4-[2-Amino-6-(5-bromo-2-ethoxy-phenyl)-pyrimidin-4-ylamino]-phenyl}-ethanone oxime
   Show/Hide
 C20H20BrN5O2  1
1
IC50 < 50 nM
   TI
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CP0922360
 Compound Info 
1,3-di((E)-dec-1-enyl)-2,4-dimethyl-7,8,9,10-tetrahydro-6H-pyrido[1,2-a]azepinium 2,2,2-trifluoroacetate
   Show/Hide
 C34H54F3NO2  1
1
ED50 = 600 nM
   TI
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CP0961810
 Compound Info 
(E)-3-(3-chlorophenyl)-N-(2-((1,1-dioxidotetrahydro-2H-thiopyran-4-yl)(methyl)amino)-2-oxoethyl)acrylamide
   Show/Hide
 C17H21ClN2O4S  1
1
IC50 = 470 nM
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   TS
Protein family and CMB statistics Related to the Cell Line
Cell Lines Derived from the same Tissue Source (Brain)
Cell Line Name Organism Disease
TS603
 Cell Line Info 
Homo sapiens (Human) Anaplastic oligodendroglioma
H4
 Cell Line Info 
Homo sapiens (Human) Astrocytoma
1321N1
 Cell Line Info 
Homo sapiens (Human) Astrocytoma
SNB-19
 Cell Line Info 
Homo sapiens (Human) Astrocytoma
U-251MG
 Cell Line Info 
Homo sapiens (Human) Astrocytoma
U-373MG ATCC
 Cell Line Info 
Homo sapiens (Human) Astrocytoma
LN-308
 Cell Line Info 
Homo sapiens (Human) Astrocytoma
CCF-STTG1
 Cell Line Info 
Homo sapiens (Human) Astrocytoma
LN-319
 Cell Line Info 
Homo sapiens (Human) Astrocytoma
P2X7-1321N1
 Cell Line Info 
Homo sapiens (Human) Astrocytoma
MDA-MB-361
 Cell Line Info 
Homo sapiens (Human) Breast adenocarcinoma
JEG-3
 Cell Line Info 
Homo sapiens (Human) Gestational choriocarcinoma
D3 [Human glioblastoma]
 Cell Line Info 
Homo sapiens (Human) Glioblastoma
LN-229
 Cell Line Info 
Homo sapiens (Human) Glioblastoma
LN-18
 Cell Line Info 
Homo sapiens (Human) Glioblastoma
A-172
 Cell Line Info 
Homo sapiens (Human) Glioblastoma
UC-11MG
 Cell Line Info 
Homo sapiens (Human) Glioblastoma
T98G
 Cell Line Info 
Homo sapiens (Human) Glioblastoma
LN229-V6R
 Cell Line Info 
Homo sapiens (Human) Glioblastoma
SF539
 Cell Line Info 
Homo sapiens (Human) Gliosarcoma
MED1
 Cell Line Info 
Homo sapiens (Human) Medulloblastoma, non-WNT/non-SHH, group 4
Kelly
 Cell Line Info 
Homo sapiens (Human) Neuroblastoma
PFSK-1
 Cell Line Info 
Homo sapiens (Human) Primitive neuroectodermal tumor
DU145-TxR
 Cell Line Info 
Homo sapiens (Human) Prostate carcinoma
GL261
 Cell Line Info 
Mus musculus (Mouse) Mouse glioblastoma
C6
 Cell Line Info 
Rattus norvegicus (Rat) Rat malignant glioma
C6-BU-1
 Cell Line Info 
Rattus norvegicus (Rat) Rat malignant glioma
RG2
 Cell Line Info 
Rattus norvegicus (Rat) Rat malignant glioma
ReNcell VM
 Cell Line Info 
Homo sapiens (Human) -
hCMEC/D3
 Cell Line Info 
Homo sapiens (Human) -
BV-2
 Cell Line Info 
Mus musculus (Mouse) -
C17.2
 Cell Line Info 
Mus musculus (Mouse) -
ScGT1
 Cell Line Info 
Mus musculus (Mouse) -
bEnd.4
 Cell Line Info 
Mus musculus (Mouse) -
N39
 Cell Line Info 
Mus musculus (Mouse) -
GT1-7
 Cell Line Info 
Mus musculus (Mouse) -
N27-A
 Cell Line Info 
Rattus norvegicus (Rat) -
RBE4
 Cell Line Info 
Rattus norvegicus (Rat) -