General Information of the Cell Line
Cell Line ID
CL000881
Cell Line Name
P2X7-1321N1
Category
Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0110
Tissue Information
Brain
Disease
Astrocytoma (NCIt: C60781)
Astrocytoma (ORDO: Orphanet_94)
Map of Molecular Bioactivity Related to the Cell Line
Map of Molecular Bioactivity Related to the Cell Line

Cell Line
Protein
Compound

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Cell Line
Protein ID: PT01449, P2X purinoceptor 7
Compound ID Compound Name Compound Formula
CP0391607
US10047092, 13
   Show/Hide
C17H14Cl2N6O
 1
1
Ki = 1.4 nM
   TI
   LI
   LO
   TS
CP0484511
US10047092, 21
   Show/Hide
C17H13ClF3N5O2
 1
1
Ki = 1.4 nM
   TI
   LI
   LO
   TS
CP0056677
US10047092, 16
   Show/Hide
C18H14ClF3N6O
 1
1
Ki = 1.6 nM
   TI
   LI
   LO
   TS
CP0385599
BDBM160086
   Show/Hide
C18H14ClF3N6O
 1
1
Ki = 2 nM
   TI
   LI
   LO
   TS
CP0417275
US10047092, 32
   Show/Hide
C17H13ClF3N5OS
 1
1
Ki = 2 nM
   TI
   LI
   LO
   TS
CP0419739
US10047092, 35
   Show/Hide
C20H17ClF3N5O2
 1
1
Ki = 2 nM
   TI
   LI
   LO
   TS
CP0541424
US10047092, 37
   Show/Hide
C17H13ClF3N5OS
 1
1
Ki = 2 nM
   TI
   LI
   LO
   TS
CP0380496
US10047092, 76
   Show/Hide
C20H16ClF4N5O
 1
1
Ki = 2.5 nM
   TI
   LI
   LO
   TS
CP0381007
US10047092, 30
   Show/Hide
C19H14ClF4N5O
 1
1
Ki = 2.5 nM
   TI
   LI
   LO
   TS
CP0384906
US10047092, 34
   Show/Hide
C18H13ClF4N6O
 1
1
Ki = 2.5 nM
   TI
   LI
   LO
   TS
CP0512552
US10047092, 11
   Show/Hide
C17H14Cl2N6O
 1
1
Ki = 2.5 nM
   TI
   LI
   LO
   TS
CP0403649
US10047092, 75
   Show/Hide
C19H15ClF4N6O
 1
1
Ki = 3.2 nM
   TI
   LI
   LO
   TS
CP0408299
US10047092, 23
   Show/Hide
C18H16ClF3N6O
 1
1
Ki = 3.2 nM
   TI
   LI
   LO
   TS
CP0422528
US10047092, 63
   Show/Hide
C20H16ClF3N6O
 1
1
Ki = 3.2 nM
   TI
   LI
   LO
   TS
CP0429645
US10047092, 19
   Show/Hide
C19H16ClF3N6O
 1
1
Ki = 3.2 nM
   TI
   LI
   LO
   TS
CP0846069
US9040534, 28
   Show/Hide
C17H14ClF3N6O
 1
1
Ki = 3.2 nM
   TI
   LI
   LO
   TS
CP0877279
US9040534, 26
   Show/Hide
C18H16ClF3N6O
 1
1
Ki = 3.2 nM
   TI
   LI
   LO
   TS
CP0385598
US10047092, 29
   Show/Hide
C19H15ClF3N5O
 1
1
Ki = 4 nM
   TI
   LI
   LO
   TS
CP0397177
US10047092, 14
   Show/Hide
C18H14ClF3N6O
 1
1
Ki = 4 nM
   TI
   LI
   LO
   TS
CP0407689
US10047092, 20
   Show/Hide
C17H13ClF3N5O2
 1
1
Ki = 4 nM
   TI
   LI
   LO
   TS
CP0508728
US10047092, 31
   Show/Hide
C17H13ClF3N5OS
 1
1
Ki = 4 nM
   TI
   LI
   LO
   TS
CP0880953
US9040534, 68
   Show/Hide
C19H16ClF3N6O
 1
1
Ki = 4 nM
   TI
   LI
   LO
   TS
CP0472424
US10053462, 61
   Show/Hide
C19H14ClF3N4OS
 1
1
Ki = 4 nM
   TI
   LI
   LO
   TS
CP0385042
US10047092, 18
   Show/Hide
C19H15ClF3N5O
 1
1
Ki = 5 nM
   TI
   LI
   LO
   TS
CP0385597
US10047092, 33
   Show/Hide
C18H14ClF3N6O
 1
1
Ki = 5 nM
   TI
   LI
   LO
   TS
CP0385625
US10047092, 85
   Show/Hide
C19H17F3N6O
 1
1
Ki = 5 nM
   TI
   LI
   LO
   TS
CP0427095
US10047092, 66
   Show/Hide
C20H16ClF3N6O
 1
1
Ki = 5 nM
   TI
   LI
   LO
   TS
CP0456896
US10047092, 88
   Show/Hide
C18H15F3N6O
 1
1
Ki = 5 nM
   TI
   LI
   LO
   TS
CP0389368
US10047092, 64
   Show/Hide
C20H16ClF3N6O
 1
1
Ki = 6.3 nM
   TI
   LI
   LO
   TS
CP0416388
US10047092, 56
   Show/Hide
C19H14Cl2F3N5O
 1
1
Ki = 6.3 nM
   TI
   LI
   LO
   TS
CP0460008
US10047092, 22
   Show/Hide
C17H13ClF3N5O2
 1
1
Ki = 6.3 nM
   TI
   LI
   LO
   TS
CP0527398
US10047092, 45
   Show/Hide
C19H14ClF4N5O
 1
1
Ki = 6.3 nM
   TI
   LI
   LO
   TS
CP0539442
US10047092, 3
   Show/Hide
C17H12ClF3N6O
 1
1
Ki = 6.3 nM
   TI
   LI
   LO
   TS
CP0931107
US9096596, 75
   Show/Hide
C20H17F4N5O
 1
1
Ki = 6.3 nM
   TI
   LI
   LO
   TS
CP0945719
US9102686, 62
   Show/Hide
C19H15ClF3N5O
 1
1
Ki = 6.3 nM
   TI
   LI
   LO
   TS
CP0375375
US10047092, 17
   Show/Hide
C20H15ClF4N4O
 1
1
Ki = 7.9 nM
   TI
   LI
   LO
   TS
CP0389315
US10047092, 61
   Show/Hide
C20H16ClF3N6O
 1
1
Ki = 7.9 nM
   TI
   LI
   LO
   TS
CP0403042
US10047092, 70
   Show/Hide
C20H15ClF4N6O
 1
1
Ki = 7.9 nM
   TI
   LI
   LO
   TS
CP0407144
US10047092, 52
   Show/Hide
C19H14Cl2F3N5O
 1
1
Ki = 7.9 nM
   TI
   LI
   LO
   TS
CP0524290
US10047092, 42
   Show/Hide
C18H13BrClF3N6O
 1
1
Ki = 7.9 nM
   TI
   LI
   LO
   TS
CP0546701
US10047092, 67
   Show/Hide
C21H17ClF3N5O
 1
1
Ki = 7.9 nM
   TI
   LI
   LO
   TS
CP0863315
US9096596, 78
   Show/Hide
C21H20F3N5O
 1
1
Ki = 7.9 nM
   TI
   LI
   LO
   TS
CP0896590
US9096596, 113
   Show/Hide
C19H15ClF3N5O
 1
1
Ki = 7.9 nM
   TI
   LI
   LO
   TS
CP0935337
US9096596, 81
   Show/Hide
C19H16Cl2FN5O
 1
1
Ki = 7.9 nM
   TI
   LI
   LO
   TS
CP0462829
US10047092, 54
   Show/Hide
C19H13ClF6N6O
 1
1
Ki = 10 nM
   TI
   LI
   LO
   TS
CP0513238
US10047092, 9
   Show/Hide
C18H13ClF3N5O
 1
1
Ki = 10 nM
   TI
   LI
   LO
   TS
CP0860077
US9040534, 74
   Show/Hide
C18H16ClF3N6O
 1
1
Ki = 10 nM
   TI
   LI
   LO
   TS
CP0903792
US9096596, 84
   Show/Hide
C19H17Cl2N5O
 1
1
Ki = 10 nM
   TI
   LI
   LO
   TS
CP0388923
US10053462, 47
   Show/Hide
C18H13Cl2FN6O
 1
1
Ki = 10 nM
   TI
   LI
   LO
   TS
CP0407681
US10053462, 8
   Show/Hide
C19H15ClF3N5OS
 1
1
Ki = 10 nM
   TI
   LI
   LO
   TS
CP0470360
US10053462, 58
   Show/Hide
C19H14ClF3N4OS
 1
1
Ki = 10 nM
   TI
   LI
   LO
   TS
CP0400904
US10053462, 33
   Show/Hide
C21H17ClF3N5O
 1
1
Ki = 10.5 nM
   TI
   LI
   LO
   TS
CP0414577
US10053462, 36
   Show/Hide
C19H15ClF3N5OS
 1
1
Ki = 10.7 nM
   TI
   LI
   LO
   TS
CP0863273
US9096596, 89
   Show/Hide
C19H17ClFN5O
 1
1
Ki = 11.5 nM
   TI
   LI
   LO
   TS
CP0409905
US10047092, 73
   Show/Hide
C20H17ClF3N5O
 1
1
Ki = 12.6 nM
   TI
   LI
   LO
   TS
CP0420025
US10047092, 41
   Show/Hide
C17H13ClF3N5O2
 1
1
Ki = 12.6 nM
   TI
   LI
   LO
   TS
CP0434339
US10047092, 46
   Show/Hide
C20H17ClF3N5O
 1
1
Ki = 12.6 nM
   TI
   LI
   LO
   TS
CP0462711
US10047092, 48
   Show/Hide
C20H17ClF3N5O
 1
1
Ki = 12.6 nM
   TI
   LI
   LO
   TS
CP0509221
US10323032, Example 109
   Show/Hide
C17H12ClF3N6O
 1
1
Ki = 12.6 nM
   TI
   LI
   LO
   TS
CP0850616
US9096596, 118
   Show/Hide
C18H14Cl2FN5O
 1
1
Ki = 12.6 nM
   TI
   LI
   LO
   TS
CP0866477
US9096596, 119
   Show/Hide
C18H14Cl2FN5O
 1
1
Ki = 12.6 nM
   TI
   LI
   LO
   TS
CP0866681
US9096596, 71
   Show/Hide
C19H16Cl2FN5O
 1
1
Ki = 12.6 nM
   TI
   LI
   LO
   TS
CP0894646
US9096596, 67
   Show/Hide
C19H17Cl2N5O
 1
1
Ki = 12.6 nM
   TI
   LI
   LO
   TS
CP0384797
US10053462, 41
   Show/Hide
C20H15ClF3N5O
 1
1
Ki = 12.6 nM
   TI
   LI
   LO
   TS
CP0385435
US10053462, 7
   Show/Hide
C19H15ClF3N5OS
 1
1
Ki = 12.6 nM
   TI
   LI
   LO
   TS
CP0385779
US10053462, 44
   Show/Hide
C21H18F3N5O
 1
1
Ki = 12.6 nM
   TI
   LI
   LO
   TS
CP0396418
US10053462, 12
   Show/Hide
C21H16ClF4N5O
 1
1
Ki = 12.6 nM
   TI
   LI
   LO
   TS
CP0407607
US10053462, 45
   Show/Hide
C20H14ClF4N5O
 1
1
Ki = 12.6 nM
   TI
   LI
   LO
   TS
CP0414717
US10053462, 42
   Show/Hide
C19H14ClF3N6O
 1
1
Ki = 12.6 nM
   TI
   LI
   LO
   TS
CP0425425
US10053462, 5
   Show/Hide
C22H17ClF4N4O
 1
1
Ki = 12.6 nM
   TI
   LI
   LO
   TS
CP0456491
US10053462, 53
   Show/Hide
C19H16F3N5OS
 1
1
Ki = 12.6 nM
   TI
   LI
   LO
   TS
CP0422523
US10053462, 43
   Show/Hide
C20H14ClF4N5O
 1
1
Ki = 12.9 nM
   TI
   LI
   LO
   TS
CP0468095
US10053462, 18
   Show/Hide
C20H15ClF4N6O
 1
1
Ki = 13.8 nM
   TI
   LI
   LO
   TS
CP0411939
US10047092, 94
   Show/Hide
C18H18N6O
 1
1
Ki = 14.1 nM
   TI
   LI
   LO
   TS
CP0407563
US10323032, Example 7
   Show/Hide
C17H13Cl2N5O
 1
1
Ki = 15.4 nM
   TI
   LI
   LO
   TS
CP0389346
US10047092, 47
   Show/Hide
C19H15ClF3N5O
 1
1
Ki = 15.8 nM
   TI
   LI
   LO
   TS
CP0434796
US10047092, 78
   Show/Hide
C17H14ClFN6O
 1
1
Ki = 15.8 nM
   TI
   LI
   LO
   TS
CP0868205
US9096596, 68
   Show/Hide
C19H17Cl2N5O
 1
1
Ki = 15.8 nM
   TI
   LI
   LO
   TS
CP0879023
US9096596, 58
   Show/Hide
C20H17ClF3N5O
 1
1
Ki = 15.8 nM
   TI
   LI
   LO
   TS
CP0420624
US10053462, 50
   Show/Hide
C19H13ClF4N6O
 1
1
Ki = 15.8 nM
   TI
   LI
   LO
   TS
CP0541397
US10053462, 46
   Show/Hide
C19H14ClF3N6O
 1
1
Ki = 15.8 nM
   TI
   LI
   LO
   TS
CP0403398
US10323032, Example 33
   Show/Hide
C19H15ClF3N5O
 1
1
Ki = 16.4 nM
   TI
   LI
   LO
   TS
CP0861656
US9096596, 99
   Show/Hide
C21H19ClF3N5O
 1
1
Ki = 17.4 nM
   TI
   LI
   LO
   TS
CP0515335
US10053462, 14
   Show/Hide
C21H17ClF3N5O
 1
1
Ki = 17.4 nM
   TI
   LI
   LO
   TS
CP0470140
US10323032, Example 55
   Show/Hide
C18H14ClF3N6O
 1
1
Ki = 17.8 nM
   TI
   LI
   LO
   TS
CP0408165
US10047092, 40
   Show/Hide
C18H15ClF3N5OS
 1
1
Ki = 20 nM
   TI
   LI
   LO
   TS
CP0469293
US10047092, 8
   Show/Hide
C17H13Cl2N5O
 1
1
Ki = 20 nM
   TI
   LI
   LO
   TS
CP0469296
US10323032, Example 18
   Show/Hide
C18H13ClF3N5O
 1
1
Ki = 20 nM
   TI
   LI
   LO
   TS
CP0880632
US9096596, 122
   Show/Hide
C18H14Cl2FN5O
 1
1
Ki = 20 nM
   TI
   LI
   LO
   TS
CP0902249
US9096596, 102
   Show/Hide
C22H21ClF3N5O
 1
1
Ki = 20 nM
   TI
   LI
   LO
   TS
CP0902265
US9096596, 121
   Show/Hide
C18H14Cl2FN5O
 1
1
Ki = 20 nM
   TI
   LI
   LO
   TS
CP0397123
US10053462, 49
   Show/Hide
C18H13ClF3N5OS
 1
1
Ki = 20 nM
   TI
   LI
   LO
   TS
CP0491218
US10053462, 4
   Show/Hide
C22H17ClF4N4O
 1
1
Ki = 20 nM
   TI
   LI
   LO
   TS
CP0407608
US10053462, 40
   Show/Hide
C21H15ClF4N4O
 1
1
Ki = 21.9 nM
   TI
   LI
   LO
   TS
CP0408243
US10053462, 60
   Show/Hide
C18H12Cl2F3N5OS
 1
1
Ki = 21.9 nM
   TI
   LI
   LO
   TS
CP0913936
US9096596, 63
   Show/Hide
C19H16ClF3N6O
 1
1
Ki = 22.4 nM
   TI
   LI
   LO
   TS
CP0473488
US10053462, 23
   Show/Hide
C22H19ClF3N5O
 1
1
Ki = 24 nM
   TI
   LI
   LO
   TS
CP0456513
US10047092, 24
   Show/Hide
C18H16ClF3N6O
 1
1
Ki = 25.1 nM
   TI
   LI
   LO
   TS
CP0540780
US10047092, 36
   Show/Hide
C18H15ClF3N5OS
 1
1
Ki = 25.1 nM
   TI
   LI
   LO
   TS
CP0865045
US9040534, 25
   Show/Hide
C17H14ClF3N6O
 1
1
Ki = 25.1 nM
   TI
   LI
   LO
   TS
CP0385544
US10323032, Example 124
   Show/Hide
C22H20ClF4N5O
 1
1
Ki = 25.1 nM
   TI
   LI
   LO
   TS
CP0420230
US10323032, Example 19
   Show/Hide
C19H15ClF3N5O
 1
1
Ki = 25.1 nM
   TI
   LI
   LO
   TS
CP0440539
US10323032, Example 20
   Show/Hide
C17H12Cl2FN5O
 1
1
Ki = 25.1 nM
   TI
   LI
   LO
   TS
CP0860052
US9096596, 91
   Show/Hide
C19H17ClFN5O
 1
1
Ki = 25.1 nM
   TI
   LI
   LO
   TS
CP0861884
US9096596, 112
   Show/Hide
C19H15ClF3N5O
 1
1
Ki = 25.1 nM
   TI
   LI
   LO
   TS
CP0874169
US9096596, 74
   Show/Hide
C20H17F4N5O
 1
1
Ki = 25.1 nM
   TI
   LI
   LO
   TS
CP0892017
US9096596, 80
   Show/Hide
C19H16Cl2FN5O
 1
1
Ki = 25.1 nM
   TI
   LI
   LO
   TS
CP0911517
US9096596, 62
   Show/Hide
C19H15ClF3N5O
 1
1
Ki = 25.1 nM
   TI
   LI
   LO
   TS
CP0420629
US10053462, 39
   Show/Hide
C20H17ClF3N5OS
 1
1
Ki = 25.1 nM
   TI
   LI
   LO
   TS
CP0474346
US10053462, 55
   Show/Hide
C19H13Cl2F3N4OS
 1
1
Ki = 25.1 nM
   TI
   LI
   LO
   TS
CP0487012
US10053462, 54
   Show/Hide
C17H12Cl2FN5OS
 1
1
Ki = 25.1 nM
   TI
   LI
   LO
   TS
CP0385693
US10047092, 39
   Show/Hide
C19H17ClF3N5OS
 1
1
Ki = 27.5 nM
   TI
   LI
   LO
   TS
CP0414124
US10047092, 2
   Show/Hide
C16H12Cl2N6O
 1
1
Ki = 28.8 nM
   TI
   LI
   LO
   TS
CP0524252
US10053462, 26
   Show/Hide
C22H19ClF3N5O2
 1
1
Ki = 30.4 nM
   TI
   LI
   LO
   TS
CP0385144
US10323032, Example 10
   Show/Hide
C19H16F3N5O
 1
1
Ki = 30.9 nM
   TI
   LI
   LO
   TS
CP0385776
US10047092, 92
   Show/Hide
C18H18N6O
 1
1
Ki = 31.6 nM
   TI
   LI
   LO
   TS
CP0407605
US10047092, 69
   Show/Hide
C21H16ClF4N5O
 1
1
Ki = 31.6 nM
   TI
   LI
   LO
   TS
CP0509249
US10047092, 87
   Show/Hide
C19H20N6O
 1
1
Ki = 31.6 nM
   TI
   LI
   LO
   TS
CP0531138
US10047092, 80
   Show/Hide
C17H15ClN6O
 1
1
Ki = 31.6 nM
   TI
   LI
   LO
   TS
CP0487017
US10323032, Example 128
   Show/Hide
C23H23ClF3N5O2
 1
1
Ki = 31.6 nM
   TI
   LI
   LO
   TS
CP0850480
US9096596, 77
   Show/Hide
C21H20F3N5O
 1
1
Ki = 31.6 nM
   TI
   LI
   LO
   TS
CP0852696
US9096596, 87
   Show/Hide
C19H17ClFN5O
 1
1
Ki = 31.6 nM
   TI
   LI
   LO
   TS
CP0867838
US9096596, 95
   Show/Hide
C19H17F2N5O
 1
1
Ki = 31.6 nM
   TI
   LI
   LO
   TS
CP0869093
US9096596, 116
   Show/Hide
C19H14ClF4N5O
 1
1
Ki = 31.6 nM
   TI
   LI
   LO
   TS
CP0880918
US9096596, 115
   Show/Hide
C19H14ClF4N5O
 1
1
Ki = 31.6 nM
   TI
   LI
   LO
   TS
CP0895816
US9096596, 83
   Show/Hide
C19H17Cl2N5O
 1
1
Ki = 31.6 nM
   TI
   LI
   LO
   TS
CP0407838
US10053462, 52
   Show/Hide
C18H12ClF4N5OS
 1
1
Ki = 31.6 nM
   TI
   LI
   LO
   TS
CP0389387
US10053462, 57
   Show/Hide
C18H13ClF3N5OS
 1
1
Ki = 35.5 nM
   TI
   LI
   LO
   TS
CP0472506
US10053462, 30
   Show/Hide
C21H16Cl2F3N5O
 1
1
Ki = 35.5 nM
   TI
   LI
   LO
   TS
CP0417817
US10323032, Example 11
   Show/Hide
C19H14Cl2N4O
 1
1
Ki = 37.2 nM
   TI
   LI
   LO
   TS
CP0846324
US9096596, 56
   Show/Hide
C20H17ClF3N5O
 1
1
Ki = 37.2 nM
   TI
   LI
   LO
   TS
CP0375674
US10323032, Example 129
   Show/Hide
C19H12Cl2F2N4O
 1
1
Ki = 39.8 nM
   TI
   LI
   LO
   TS
CP0403429
US10323032, Example 21
   Show/Hide
C17H13ClFN5O
 1
1
Ki = 39.8 nM
   TI
   LI
   LO
   TS
CP0406949
US10323032, Example 35
   Show/Hide
C19H14ClF4N5O
 1
1
Ki = 39.8 nM
   TI
   LI
   LO
   TS
CP0407229
US10323032, Example 47
   Show/Hide
C18H14ClF3N6O
 1
1
Ki = 39.8 nM
   TI
   LI
   LO
   TS
CP0861572
US9096596, 70
   Show/Hide
C19H16Cl2FN5O
 1
1
Ki = 39.8 nM
   TI
   LI
   LO
   TS
CP0863311
US9096596, 104
   Show/Hide
C20H18Cl2FN5O
 1
1
Ki = 39.8 nM
   TI
   LI
   LO
   TS
CP0375035
US10053462, 3
   Show/Hide
C20H16ClF3N6O
 1
1
Ki = 39.8 nM
   TI
   LI
   LO
   TS
CP0407675
US10053462, 48
   Show/Hide
C20H15ClF3N5O
 1
1
Ki = 39.8 nM
   TI
   LI
   LO
   TS
CP0456469
US10053462, 56
   Show/Hide
C19H15ClF3N5OS
 1
1
Ki = 39.8 nM
   TI
   LI
   LO
   TS
CP0863244
US9102686, 51
   Show/Hide
C19H16ClF3N6O
 1
1
Ki = 39.8 nM
   TI
   LI
   LO
   TS
CP0546809
US10047092, 57
   Show/Hide
C20H17ClF3N5O
 1
1
Ki = 50.1 nM
   TI
   LI
   LO
   TS
CP0388932
US10323032, Example 39
   Show/Hide
C20H14ClF6N5O
 1
1
Ki = 50.1 nM
   TI
   LI
   LO
   TS
CP0403003
US10323032, Example 43
   Show/Hide
C18H12ClF3N4OS
 1
1
Ki = 50.1 nM
   TI
   LI
   LO
   TS
CP0524278
US10323032, Example 37
   Show/Hide
C18H12ClF3N4OS
 1
1
Ki = 50.1 nM
   TI
   LI
   LO
   TS
CP0544596
US10323032, Example 111
   Show/Hide
C18H13F4N5O
 1
1
Ki = 50.1 nM
   TI
   LI
   LO
   TS
CP0690977
US9096596, 66
   Show/Hide
C20H16ClF4N5O
 1
1
Ki = 50.1 nM
   TI
   LI
   LO
   TS
CP0375684
US10053462, 1
   Show/Hide
C20H16ClF3N6O
 1
1
Ki = 50.1 nM
   TI
   LI
   LO
   TS
CP0411350
US10053462, 21
   Show/Hide
C19H15Cl2FN6O
 1
1
Ki = 50.1 nM
   TI
   LI
   LO
   TS
CP0848326
US9096596, 98
   Show/Hide
C21H19ClF3N5O
 1
1
Ki = 55 nM
   TI
   LI
   LO
   TS
CP0305154
US10323032, Example 12
   Show/Hide
C20H14ClF3N4O
 1
1
Ki = 58.9 nM
   TI
   LI
   LO
   TS
CP0425315
US10047092, 86
   Show/Hide
C17H14Cl2N6O
 1
1
Ki = 63.1 nM
   TI
   LI
   LO
   TS
CP0457552
US10047092, 82
   Show/Hide
C18H17ClN6O3S
 1
1
Ki = 63.1 nM
   TI
   LI
   LO
   TS
CP0474497
US10047092, 1
   Show/Hide
C19H13ClF4N4O
 1
1
Ki = 63.1 nM
   TI
   LI
   LO
   TS
CP0385845
US10323032, Example 14
   Show/Hide
C18H13Cl2N5O
 1
1
Ki = 63.1 nM
   TI
   LI
   LO
   TS
CP0396423
US10323032, Example 44
   Show/Hide
C19H14ClF3N4OS
 1
1
Ki = 63.1 nM
   TI
   LI
   LO
   TS
CP0403490
US10323032, Example 57
   Show/Hide
C21H17ClF3N5O
 1
1
Ki = 63.1 nM
   TI
   LI
   LO
   TS
CP0409865
US10323032, Example 53
   Show/Hide
C18H14Cl2FN5O
 1
1
Ki = 63.1 nM
   TI
   LI
   LO
   TS
CP0411397
US10323032, Example 34
   Show/Hide
C18H15Cl2N5O
 1
1
Ki = 63.1 nM
   TI
   LI
   LO
   TS
CP0435051
US10323032, Example 130
   Show/Hide
C20H13ClF4N4O
 1
1
Ki = 63.1 nM
   TI
   LI
   LO
   TS
CP0382526
US10323032, Example 38
   Show/Hide
C17H12Cl2N4OS
 1
1
Ki = 77.6 nM
   TI
   LI
   LO
   TS
CP0382104
US10323032, Example 42
   Show/Hide
C19H14ClF3N4O
 1
1
Ki = 79.4 nM
   TI
   LI
   LO
   TS
CP0409841
US10323032, Example 60
   Show/Hide
C19H12ClF6N5O
 1
1
Ki = 79.4 nM
   TI
   LI
   LO
   TS
CP0462690
US10323032, Example 15
   Show/Hide
C20H16F3N5O
 1
1
Ki = 79.4 nM
   TI
   LI
   LO
   TS
CP0516657
US10323032, Example 36
   Show/Hide
C18H14Cl2FN5O
 1
1
Ki = 79.4 nM
   TI
   LI
   LO
   TS
CP0896500
US9096596, 64
   Show/Hide
C20H16ClF4N5O
 1
1
Ki = 79.4 nM
   TI
   LI
   LO
   TS
CP0414028
US10323032, Example 2
   Show/Hide
C20H15Cl2N3O
 1
1
Ki = 95.5 nM
   TI
   LI
   LO
   TS
CP0413783
US10047092, 65
   Show/Hide
C20H16ClF3N6O
 1
1
Ki = 100 nM
   TI
   LI
   LO
   TS
CP0407210
US10323032, Example 54
   Show/Hide
C20H18ClF3N6O
 1
1
Ki = 100 nM
   TI
   LI
   LO
   TS
CP0866306
US9096596, 101
   Show/Hide
C22H21ClF3N5O
 1
1
Ki = 100 nM
   TI
   LI
   LO
   TS
CP0545289
US10323032, Example 73
   Show/Hide
C21H19ClF3N5O
 1
1
Ki = 125.9 nM
   TI
   LI
   LO
   TS
CP0420519
US10053462, 59
   Show/Hide
C19H15ClF3N5OS
 1
1
Ki = 125.9 nM
   TI
   LI
   LO
   TS
CP0385627
US10047092, 93
   Show/Hide
C19H16ClF3N6O
 1
1
Ki = 158.5 nM
   TI
   LI
   LO
   TS
CP0863136
US9096596, 93
   Show/Hide
C19H17F2N5O
 1
1
Ki = 199.5 nM
   TI
   LI
   LO
   TS
CP0866497
US9096596, 97
   Show/Hide
C19H18ClN5O
 1
1
Ki = 199.5 nM
   TI
   LI
   LO
   TS
CP0400901
US10323032, Example 1
   Show/Hide
C21H15ClF3N3O
 1
1
Ki = 223.9 nM
   TI
   LI
   LO
   TS
CP0509255
US10047092, 58
   Show/Hide
C23H27ClF3N5O3
 1
1
Ki = 398.1 nM
   TI
   LI
   LO
   TS
CP0470020
US10053462, 9
   Show/Hide
C19H15ClF3N5OS
 1
1
Ki = 398.1 nM
   TI
   LI
   LO
   TS
CP0560290
US10323032, Example 27
   Show/Hide
C21H17Cl2N3O
 1
1
Ki = 426.6 nM
   TI
   LI
   LO
   TS
CP0951045
US9096596, 85
   Show/Hide
C19H17Cl2N5O
 1
1
Ki = 457.1 nM
   TI
   LI
   LO
   TS
CP0375413
US10047092, 55
   Show/Hide
C20H14ClF6N5O
 1
1
Ki = 501.2 nM
   TI
   LI
   LO
   TS
CP0937121
US9096596, 123
   Show/Hide
C18H14Cl2FN5O
 1
1
Ki = 501.2 nM
   TI
   LI
   LO
   TS
CP0429635
US10047092, 60
   Show/Hide
C19H21ClF3N5O
 1
1
Ki = 631 nM
   TI
   LI
   LO
   TS
CP0864614
US9096596, 114
   Show/Hide
C19H15ClF3N5O
 1
1
Ki = 631 nM
   TI
   LI
   LO
   TS
CP0904284
US9096596, 96
   Show/Hide
C19H18ClN5O
 1
1
Ki = 631 nM
   TI
   LI
   LO
   TS
CP0408298
US10047092, 15
   Show/Hide
C18H14ClF3N6O
 1
1
Ki = 912 nM
   TI
   LI
   LO
   TS
CP0384829
US10047092, 12
   Show/Hide
C17H14Cl2N6O
 1
1
Ki = 1584.9 nM
   TI
   LI
   LO
   TS
CP0384846
US10323032, Example 48
   Show/Hide
C18H14ClF3N6O
 1
1
Ki = 1995.3 nM
   TI
   LI
   LO
   TS
Protein family and CMB statistics Related to the Cell Line
Cell Lines Derived from the same Tissue Source (Brain)
Cell Line Name Organism Disease
TS603 Homo sapiens (Human) Anaplastic oligodendroglioma
H4 Homo sapiens (Human) Astrocytoma
1321N1 Homo sapiens (Human) Astrocytoma
SNB-19 Homo sapiens (Human) Astrocytoma
U-251MG Homo sapiens (Human) Astrocytoma
U-373MG ATCC Homo sapiens (Human) Astrocytoma
LN-308 Homo sapiens (Human) Astrocytoma
CCF-STTG1 Homo sapiens (Human) Astrocytoma
LN-319 Homo sapiens (Human) Astrocytoma
MDA-MB-361 Homo sapiens (Human) Breast adenocarcinoma
JEG-3 Homo sapiens (Human) Gestational choriocarcinoma
D3 [Human glioblastoma] Homo sapiens (Human) Glioblastoma
LN-229 Homo sapiens (Human) Glioblastoma
LN-18 Homo sapiens (Human) Glioblastoma
A-172 Homo sapiens (Human) Glioblastoma
UC-11MG Homo sapiens (Human) Glioblastoma
T98G Homo sapiens (Human) Glioblastoma
LN229-V6R Homo sapiens (Human) Glioblastoma
SF539 Homo sapiens (Human) Gliosarcoma
MED1 Homo sapiens (Human) Medulloblastoma, non-WNT/non-SHH, group 4
Kelly Homo sapiens (Human) Neuroblastoma
PFSK-1 Homo sapiens (Human) Primitive neuroectodermal tumor
DU145 Homo sapiens (Human) Prostate carcinoma
DU145-TxR Homo sapiens (Human) Prostate carcinoma
GL261 Mus musculus (Mouse) Mouse glioblastoma
C6 Rattus norvegicus (Rat) Rat malignant glioma
C6-BU-1 Rattus norvegicus (Rat) Rat malignant glioma
RG2 Rattus norvegicus (Rat) Rat malignant glioma
ReNcell VM Homo sapiens (Human) -
hCMEC/D3 Homo sapiens (Human) -
BV-2 Mus musculus (Mouse) -
C17.2 Mus musculus (Mouse) -
ScGT1 Mus musculus (Mouse) -
bEnd.4 Mus musculus (Mouse) -
N39 Mus musculus (Mouse) -
GT1-7 Mus musculus (Mouse) -
N27-A Rattus norvegicus (Rat) -
RBE4 Rattus norvegicus (Rat) -