Brief Information of the Compound and Protein
Compound Name
 Compound Info 
US10047092, 42
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 PubChem ID
CID: 86279683
Canonical SMILES
C[C@H]1Cn2c(nnc2-c2ncc(Br)cn2)C(=O)N1Cc1cccc(c1Cl)C(F)(F)F
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Compound Formula C18H13BrClF3N6O
Compound Structure
Protein Name
 Protein Info 
P2X purinoceptor 7
Protein Classification
Ion channel
>
Ligand-gated ion channel
>
P2X receptor
Uniprot ID
Q99572
Gene Name
P2RX7
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000094 1321N1
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 17.5 nM
   TI
   LI
   LO
   TS
CL000881 P2X7-1321N1
 Cell Line Info 
Homo sapiens (Human)  1
1
Ki = 7.9 nM
   TI
   LI
   LO
   TS