General Information of the Cell Line
Cell Line ID
CL000417
Cell Line Name
LN-229
Synonyms
LN 229
LN229
LNT-229
Category
Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0393
Tissue Information
Brain
Disease
Glioblastoma (NCIt: C3058)
Glioblastoma (ORDO: Orphanet_360)
Map of Molecular Bioactivity Related to the Cell Line
Map of Molecular Bioactivity Related to the Cell Line

Cell Line
Protein
Compound

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Cell Line
Protein ID: PT01037, Prolyl endopeptidase
Compound ID Compound Name Compound Formula
CP0044004
benzyl N-[(2S)-1-[(2S)-2-cyanopyrrolidin-1-yl]-1-oxopropan-2-yl]carbamate
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C16H19N3O3
 1
1
IC50 = 28 nM
   TI
   LI
   LO
   TS
CP0075193
benzyl N-[2-[(2S)-2-cyanopyrrolidin-1-yl]-2-oxoethyl]carbamate
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C15H17N3O3
 1
1
IC50 = 325 nM
   TI
   LI
   LO
   TS
CP0043934
(2R,5S,7R)-1-Aza-7-benzyloxycarbonylamino-8-oxo-4-thiabicyclo[3.3.0]octane-2-carbonitrile
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C15H15N3O3S
 1
1
IC50 = 2000 nM
   TI
   LI
   LO
   TS
CP0166361
benzyl N-[2-[(2R)-2-cyanopyrrolidin-1-yl]-2-oxoethyl]carbamate
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C15H17N3O3
 1
1
IC50 = 3400 nM
   TI
   LI
   LO
   TS
CP0181871
benzyl N-[(2R)-1-[(2S)-2-cyanopyrrolidin-1-yl]-1-oxopropan-2-yl]carbamate
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C16H19N3O3
 1
1
IC50 = 7500 nM
   TI
   LI
   LO
   TS
Cell Viability or Cytotoxicity Assay
Compound ID Compound Name Compound Formula
CP0533915
2-[4-[[(2R)-2-aminobutyl]amino]pyrimidin-2-yl]-4-(1-methylpyrazol-4-yl)phenol
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C18H22N6O  1
1
IC50 = 600 nM
   TI
   LI
   LO
   TS
Protein family and CMB statistics Related to the Cell Line
Cell Lines Derived from the same Tissue Source (Brain)
Cell Line Name Organism Disease
TS603 Homo sapiens (Human) Anaplastic oligodendroglioma
H4 Homo sapiens (Human) Astrocytoma
1321N1 Homo sapiens (Human) Astrocytoma
SNB-19 Homo sapiens (Human) Astrocytoma
U-251MG Homo sapiens (Human) Astrocytoma
U-373MG ATCC Homo sapiens (Human) Astrocytoma
LN-308 Homo sapiens (Human) Astrocytoma
CCF-STTG1 Homo sapiens (Human) Astrocytoma
LN-319 Homo sapiens (Human) Astrocytoma
P2X7-1321N1 Homo sapiens (Human) Astrocytoma
MDA-MB-361 Homo sapiens (Human) Breast adenocarcinoma
JEG-3 Homo sapiens (Human) Gestational choriocarcinoma
D3 [Human glioblastoma] Homo sapiens (Human) Glioblastoma
LN-18 Homo sapiens (Human) Glioblastoma
A-172 Homo sapiens (Human) Glioblastoma
UC-11MG Homo sapiens (Human) Glioblastoma
T98G Homo sapiens (Human) Glioblastoma
LN229-V6R Homo sapiens (Human) Glioblastoma
SF539 Homo sapiens (Human) Gliosarcoma
MED1 Homo sapiens (Human) Medulloblastoma, non-WNT/non-SHH, group 4
Kelly Homo sapiens (Human) Neuroblastoma
PFSK-1 Homo sapiens (Human) Primitive neuroectodermal tumor
DU145 Homo sapiens (Human) Prostate carcinoma
DU145-TxR Homo sapiens (Human) Prostate carcinoma
GL261 Mus musculus (Mouse) Mouse glioblastoma
C6 Rattus norvegicus (Rat) Rat malignant glioma
C6-BU-1 Rattus norvegicus (Rat) Rat malignant glioma
RG2 Rattus norvegicus (Rat) Rat malignant glioma
ReNcell VM Homo sapiens (Human) -
hCMEC/D3 Homo sapiens (Human) -
BV-2 Mus musculus (Mouse) -
C17.2 Mus musculus (Mouse) -
ScGT1 Mus musculus (Mouse) -
bEnd.4 Mus musculus (Mouse) -
N39 Mus musculus (Mouse) -
GT1-7 Mus musculus (Mouse) -
N27-A Rattus norvegicus (Rat) -
RBE4 Rattus norvegicus (Rat) -