(2S)-2-[[(2S)-1-[(2S)-6-amino-2-[[(2S)-1-[(2S)-2-amino-5-(diaminomethylideneamino)pentanoyl]pyrrolidine-2-carbonyl]amino]hexanoyl]pyrrolidine-2-carbonyl]amino]-N-[(2S)-5-amino-1-[[(2S)-1-[[(2S)-1-[[2-[[(2S)-1-[[(2S)-1-amino-4-methylsulfonyl-1-oxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]-methylamino]-1-oxo-3-phenylpropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-1,5-dioxopentan-2-yl]pentanediamide

4-(3,5-Bis-trifluoromethyl-benzyloxymethyl)-1-methyl-4-phenyl-piperidine

N-ethyl-6-[[4-(4-fluorophenyl)-1-methylpiperidin-4-yl]methoxymethyl]-N-methyl-4-(trifluoromethyl)pyridin-2-amine

4-(3,5-Bis-trifluoromethyl-benzyloxymethyl)-4-phenyl-piperidine

2-[(1-methyl-4-phenylpiperidin-4-yl)methoxymethyl]-6-pyrrolidin-1-yl-4-(trifluoromethyl)pyridine

N,N-diethyl-6-[[4-(4-fluorophenyl)-1-methylpiperidin-4-yl]methoxymethyl]-4-(trifluoromethyl)pyridin-2-amine

2,4-dicyclopropyl-6-[[4-(4-fluorophenyl)-1-methylpiperidin-4-yl]methoxymethyl]pyridine

BMS-817693

2-[6-[[4-(4-fluorophenyl)-1-methylpiperidin-4-yl]methoxymethyl]-4-(trifluoromethyl)pyridin-2-yl]-2-azabicyclo[3.1.0]hexane

2-cyclopropyl-6-[(1-methyl-4-phenylpiperidin-4-yl)methoxymethyl]-4-(trifluoromethyl)pyridine

2-cyclopropyl-6-[(4-phenylpiperidin-4-yl)methoxymethyl]-4-(trifluoromethyl)pyridine

5-[[3,5-bis(trifluoromethyl)phenyl]methoxymethyl]-5-phenylazocane

(4R)-4-[[3,5-bis(trifluoromethyl)phenyl]methoxymethyl]-4-phenylazepane

(4R)-4-[[3,5-bis(trifluoromethyl)phenyl]methoxymethyl]-1-methyl-4-phenylazepane

(4S)-4-[[3,5-bis(trifluoromethyl)phenyl]methoxymethyl]-4-phenylazepane

2-[(4-phenylpiperidin-4-yl)methoxymethyl]-6-pyrrolidin-1-yl-4-(trifluoromethyl)pyridine

6-[[4-(4-fluorophenyl)-1-methylpiperidin-4-yl]methoxymethyl]-N-pentan-3-yl-4-(trifluoromethyl)pyridin-2-amine

4-[[3-chloro-5-(trifluoromethyl)phenyl]methoxymethyl]-4-phenylpiperidine

2-cyclopropyl-6-[[4-(3-fluorophenyl)-1-methylpiperidin-4-yl]methoxymethyl]-4-(trifluoromethyl)pyridine

2-(1-fluorocyclopropyl)-6-[(1-methyl-4-phenylpiperidin-4-yl)methoxymethyl]-4-(trifluoromethyl)pyridine

2-(1-fluorocyclopropyl)-6-[[4-(4-fluorophenyl)-1-methylpiperidin-4-yl]methoxymethyl]-4-(trifluoromethyl)pyridine

2-cyclopentyl-6-[[4-(4-fluorophenyl)-1-methylpiperidin-4-yl]methoxymethyl]-4-(trifluoromethyl)pyridine

2-(2,5-dihydropyrrol-1-yl)-6-[[4-(4-fluorophenyl)-1-methylpiperidin-4-yl]methoxymethyl]-4-(trifluoromethyl)pyridine

2-[[4-(3-chlorophenyl)-1-methylpiperidin-4-yl]methoxymethyl]-6-cyclopropyl-4-(trifluoromethyl)pyridine

4-[[3,5-bis(trifluoromethyl)phenyl]methoxymethyl]-4-phenylazocane

(4S)-4-[[3,5-bis(trifluoromethyl)phenyl]methoxymethyl]-1-methyl-4-phenylazepane

2-(2,2-dimethylcyclopropyl)-6-[[4-(4-fluorophenyl)-1-methylpiperidin-4-yl]methoxymethyl]-4-(trifluoromethyl)pyridine

2-[[4-(4-fluorophenyl)-1-methylpiperidin-4-yl]methoxymethyl]-6-(2-methylcyclopropyl)-4-(trifluoromethyl)pyridine

2-[[4-(4-chlorophenyl)-1-methylpiperidin-4-yl]methoxymethyl]-6-cyclopropyl-4-(trifluoromethyl)pyridine

2-chloro-6-[(4-phenylpiperidin-4-yl)methoxymethyl]-4-(trifluoromethyl)pyridine

(4S)-4-[[3,5-bis(trifluoromethyl)phenyl]methoxymethyl]-1-ethyl-4-phenylazepane

2-[[4-(4-fluorophenyl)-1-methylpiperidin-4-yl]methoxymethyl]-6-propan-2-yl-4-(trifluoromethyl)pyridine

2-chloro-6-[(1-methyl-4-phenylpiperidin-4-yl)methoxymethyl]-4-(trifluoromethyl)pyridine

1-[6-[[4-(4-fluorophenyl)-1-methylpiperidin-4-yl]methoxymethyl]-4-(trifluoromethyl)pyridin-2-yl]piperidine-4-carbonitrile

2-[[4-(4-fluorophenyl)-1-methylpiperidin-4-yl]methoxymethyl]-6-(2-methylpropyl)-4-(trifluoromethyl)pyridine

(3S)-3-[[3,5-bis(trifluoromethyl)phenyl]methoxymethyl]-3-phenylazepane

3-[[3,5-bis(trifluoromethyl)phenyl]methoxymethyl]-3-phenylpiperidine

6-[[4-(4-fluorophenyl)piperidin-4-yl]methoxymethyl]-N,N-dimethyl-4-(trifluoromethyl)pyridin-2-amine

2-[[4-(4-fluorophenyl)-1-methylpiperidin-4-yl]methoxymethyl]-6-methoxy-4-(trifluoromethyl)pyridine

(4R)-1-benzyl-4-[[3,5-bis(trifluoromethyl)phenyl]methoxymethyl]-4-phenylazepane

2-chloro-6-[[4-(4-fluorophenyl)piperidin-4-yl]methoxymethyl]-4-(trifluoromethyl)pyridine

1-[6-[[4-(4-fluorophenyl)-1-methylpiperidin-4-yl]methoxymethyl]-4-(trifluoromethyl)pyridin-2-yl]pyrrolidine-3-carbonitrile

2-[[4-(4-fluorophenyl)-1-methylpiperidin-4-yl]methoxymethyl]-6-[(E)-prop-1-enyl]-4-(trifluoromethyl)pyridine

(4R)-4-[[3,5-bis(trifluoromethyl)phenyl]methoxymethyl]-1-ethyl-4-phenylazepane

2,6-dichloro-4-[(4-phenylpiperidin-4-yl)methoxymethyl]pyridine

2-[[4-(4-fluorophenyl)-1-methylpiperidin-4-yl]methoxymethyl]-6-(2-methylprop-1-enyl)-4-(trifluoromethyl)pyridine

2-chloro-6-[[4-(4-fluorophenyl)-1-methylpiperidin-4-yl]methoxymethyl]-4-(trifluoromethyl)pyridine

2-chloro-6-[[4-(2-fluorophenyl)-1-methylpiperidin-4-yl]methoxymethyl]-4-(trifluoromethyl)pyridine

4-[[3,5-bis(trifluoromethyl)phenyl]methoxymethyl]-4-phenylpiperidin-2-one

4-chloro-2-[(1-methyl-4-phenylpiperidin-4-yl)methoxymethyl]-6-(trifluoromethyl)pyridine

4-chloro-2-[(4-phenylpiperidin-4-yl)methoxymethyl]-6-(trifluoromethyl)pyridine

(4S)-1-benzyl-4-[[3,5-bis(trifluoromethyl)phenyl]methoxymethyl]-4-phenylazepane

(3S)-3-[[3,5-bis(trifluoromethyl)phenyl]methoxymethyl]-1-methyl-3-phenylazepane

tert-butyl 4-[[3,5-bis(trifluoromethyl)phenyl]methoxymethyl]-4-phenylpiperidine-1-carboxylate

6-[[4-(4-fluorophenyl)-1-methylpiperidin-4-yl]methoxymethyl]-N,N-bis(2-methylpropyl)-4-(trifluoromethyl)pyridin-2-amine

2-cyclopropyl-6-[[4-(4-fluorophenyl)-1-methylpiperidin-4-yl]methoxymethyl]pyridine-4-carbonitrile

6-[(1-methyl-4-phenylpiperidin-4-yl)methoxymethyl]-4-(trifluoromethyl)pyridine-2-carbonitrile

(3R)-3-[[3,5-bis(trifluoromethyl)phenyl]methoxymethyl]-3-phenylazepane

2-chloro-6-[[4-(4-chlorophenyl)-1-methylpiperidin-4-yl]methoxymethyl]-4-(trifluoromethyl)pyridine

3-bromo-5-[(1-methyl-4-phenylpiperidin-4-yl)methoxymethyl]pyridine

3-bromo-5-[(4-phenylpiperidin-4-yl)methoxymethyl]pyridine

(3R)-3-[[3,5-bis(trifluoromethyl)phenyl]methoxymethyl]-1-methyl-3-phenylazepane

2-[[4-(4-fluorophenyl)-1-methylpiperidin-4-yl]methoxymethyl]-4-(trifluoromethyl)pyridine

N-ethyl-6-[[4-(4-fluorophenyl)-1-methylpiperidin-4-yl]methoxymethyl]-4-(trifluoromethyl)pyridin-2-amine

1-methyl-4-[6-[(4-phenylpiperidin-4-yl)methoxymethyl]-4-(trifluoromethyl)pyridin-2-yl]piperazine

(3S,4R)-3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)piperidine

1-[(1-phenylcyclohexyl)methoxymethyl]-3,5-bis(trifluoromethyl)benzene

(2R)-N-[(2R)-1-(2-aminoethylamino)-1-oxo-3-phenylpropan-2-yl]-2-(3,4-dichlorophenyl)-4-(6-fluoro-1-methyl-2-oxospiro[3,1-benzoxazine-4,4'-piperidine]-1'-yl)-N,2-dimethylbutanamide;2,2,2-trifluoroacetic acid

(2R)-N-[(2R)-1-(3-aminopropylamino)-1-oxo-3-phenylpropan-2-yl]-2-(3,4-dichlorophenyl)-4-(6-fluoro-1-methyl-2-oxospiro[3,1-benzoxazine-4,4'-piperidine]-1'-yl)-N,2-dimethylbutanamide;2,2,2-trifluoroacetic acid

(2R)-2-(3,4-dichlorophenyl)-4-(6-fluoro-1-methyl-2-oxospiro[3,1-benzoxazine-4,4'-piperidine]-1'-yl)-2-methyl-N-[(2R)-1-[2-(methylamino)ethylamino]-1-oxo-3-phenylpropan-2-yl]butanamide;2,2,2-trifluoroacetic acid

(2R)-2-(3,4-dichlorophenyl)-5-(6-fluoro-1-methyl-2-oxospiro[3,1-benzoxazine-4,4'-piperidine]-1'-yl)-N-[(2R)-1-(2-hydroxyethylamino)-1-oxo-3-phenylpropan-2-yl]-2-methylpentanamide

(2R)-2-(3,4-dichlorophenyl)-N-[(2R)-1-[2-(dimethylamino)ethylamino]-1-oxo-3-phenylpropan-2-yl]-5-(6-fluoro-1-methyl-2-oxospiro[3,1-benzoxazine-4,4'-piperidine]-1'-yl)-2-methylpentanamide

(2R)-N-[(2R)-1-(2-aminoethylamino)-1-oxo-3-phenylpropan-2-yl]-2-(3,4-dichlorophenyl)-4-(6-fluoro-1-methyl-2-oxospiro[3,1-benzoxazine-4,4'-piperidine]-1'-yl)-2-methylbutanamide;hydrochloride

(2R)-2-(3,4-dichlorophenyl)-4-(6-fluoro-1-methyl-2-oxospiro[3,1-benzoxazine-4,4'-piperidine]-1'-yl)-N-[(2R)-1-(2-hydroxyethylamino)-1-oxo-3-phenylpropan-2-yl]-2-methylbutanamide

(2R)-2-(3,4-dichlorophenyl)-N-[(2R)-1-[2-(dimethylamino)ethylamino]-1-oxo-3-phenylpropan-2-yl]-4-(6-fluoro-1-methyl-2-oxospiro[3,1-benzoxazine-4,4'-piperidine]-1'-yl)-2-methylbutanamide

(2R)-N-[(2S)-1-(2-aminoethylamino)-1-oxo-3-phenylpropan-2-yl]-2-(3,4-dichlorophenyl)-5-(6-fluoro-1-methyl-2-oxospiro[3,1-benzoxazine-4,4'-piperidine]-1'-yl)-N-methylpentanamide;hydrochloride

(2R)-N-[(2R)-1-(2-aminoethylamino)-1-oxo-3-phenylpropan-2-yl]-2-(3,4-dichlorophenyl)-5-(6-fluoro-1-methyl-2-oxospiro[3,1-benzoxazine-4,4'-piperidine]-1'-yl)-2-methylpentanamide;2,2,2-trifluoroacetic acid

N-[(2S,5S,8R,12R)-5,8-dibenzyl-2-(1H-indol-3-ylmethyl)-3,6,11,14-tetraoxo-1,4,7,10-tetrazacyclotetradec-12-yl]-2-(4-morpholin-4-ylpiperidin-1-yl)acetamide

(2R)-N-[(2S)-1-(2-aminoethylamino)-1-oxo-3-phenylpropan-2-yl]-2-(3,4-dichlorophenyl)-4-(6-fluoro-1-methyl-2-oxospiro[3,1-benzoxazine-4,4'-piperidine]-1'-yl)-N-methylbutanamide;hydrochloride

(2R)-N-[(2S)-1-(2-aminoethylamino)-1-oxo-3-phenylpropan-2-yl]-2-(3,4-dichlorophenyl)-4-(6-fluoro-1-methyl-2-oxospiro[3,1-benzoxazine-4,4'-piperidine]-1'-yl)-2-methylbutanamide;hydrochloride

N-[(2S,5S,8R,12R)-5,8-dibenzyl-2-(1H-indol-3-ylmethyl)-3,6,11,14-tetraoxo-1,4,7,10-tetrazacyclotetradec-12-yl]-2-(4-sulfamoylpiperazin-1-yl)acetamide

(2S)-N-[(2S)-1-(2-aminoethylamino)-1-oxo-3-phenylpropan-2-yl]-2-(3,4-dichlorophenyl)-4-(6-fluoro-1-methyl-2-oxospiro[3,1-benzoxazine-4,4'-piperidine]-1'-yl)-N-methylbutanamide;hydrochloride

(2R)-N-[(1S)-2-(2-aminoethylamino)-2-oxo-1-phenylethyl]-2-(3,4-dichlorophenyl)-4-(6-fluoro-1-methyl-2-oxospiro[3,1-benzoxazine-4,4'-piperidine]-1'-yl)-2-methylbutanamide;hydrochloride

(2R)-N-[(1S)-2-(2-aminoethylamino)-2-oxo-1-phenylethyl]-2-(3,4-dichlorophenyl)-5-(6-fluoro-1-methyl-2-oxospiro[3,1-benzoxazine-4,4'-piperidine]-1'-yl)-2-methylpentanamide;2,2,2-trifluoroacetic acid

(2S)-N-[(2S)-1-(2-aminoethylamino)-1-oxo-3-phenylpropan-2-yl]-2-(3,4-dichlorophenyl)-5-(6-fluoro-1-methyl-2-oxospiro[3,1-benzoxazine-4,4'-piperidine]-1'-yl)-N-methylpentanamide;hydrochloride

(2S)-N-[(2S)-1-(2-aminoethylamino)-1-oxo-3-phenylpropan-2-yl]-2-(3,4-dichlorophenyl)-4-(6-fluoro-1-methyl-2-oxospiro[3,1-benzoxazine-4,4'-piperidine]-1'-yl)-2-methylbutanamide;hydrochloride

(2S)-N-[(2R)-1-(2-aminoethylamino)-1-oxo-3-phenylpropan-2-yl]-2-(3,4-dichlorophenyl)-4-(6-fluoro-1-methyl-2-oxospiro[3,1-benzoxazine-4,4'-piperidine]-1'-yl)-2-methylbutanamide;hydrochloride

(2R)-N-[(1S)-2-(2-aminoethylamino)-2-oxo-1-phenylethyl]-2-(3,4-dichlorophenyl)-4-(6-fluoro-1-methyl-2-oxospiro[3,1-benzoxazine-4,4'-piperidine]-1'-yl)-N-methylbutanamide;hydrochloride