Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(2R)-2-(3,4-dichlorophenyl)-N-[(2R)-1-[2-(dimethylamino)ethylamino]-1-oxo-3-phenylpropan-2-yl]-5-(6-fluoro-1-methyl-2-oxospiro[3,1-benzoxazine-4,4'-piperidine]-1'-yl)-2-methylpentanamide
    Show/Hide
 PubChem ID
CID: 90644630
Canonical SMILES
CN(C)CCNC(=O)[C@@H](Cc1ccccc1)NC(=O)[C@](C)(CCCN1CCC2(CC1)OC(=O)N(C)c1ccc(F)cc21)c1ccc(Cl)c(Cl)c1
    Show/Hide
Compound Formula C38H46Cl2FN5O4
Compound Structure
Protein Name
 Protein Info 
Substance-P receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
>
Short peptide receptor (family A GPCR)
>
Neurokinin receptor
Uniprot ID
P25103
Gene Name
TACR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000205 U-373MG ATCC
 Cell Line Info 
Homo sapiens (Human)  1
1
Ki = 19.95 nM
   TI
   LI
   LO
   TS