Brief Information of the Compound and Protein
Compound Name
2-chloro-6-[[4-(4-chlorophenyl)-1-methylpiperidin-4-yl]methoxymethyl]-4-(trifluoromethyl)pyridine
    Show/Hide
PubChem ID
CID: 71541370
SID: 163539641
Canonical SMILES
CN1CCC(COCc2cc(cc(Cl)n2)C(F)(F)F)(CC1)c1ccc(Cl)cc1
    Show/Hide
Compound Formula C20H21Cl2F3N2O
Compound Structure
Protein Name
Substance-P receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
>
Short peptide receptor (family A GPCR)
>
Neurokinin receptor
Uniprot ID
P25103
Gene Name
TACR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000205 U-373MG ATCC Homo sapiens (Human)  1
1
IC50 = 430 nM
   TI
   LI
   LO
   TS