Cell Line Information

General Information of the Cell Line

Cell Line ID	CL000208
Cell Line Name	JEG-3
Synonyms	Jeg-3 JEG3 Jeg3 jeg3
Category	Cancer cell line
Organism	Homo sapiens (Human)
Cellosaurus ID	CVCL_0363
Tissue Information	Brain
Disease	Gestational choriocarcinoma (NCIt: C4646) Gestational choriocarcinoma (ORDO: Orphanet_99926)

Map of Molecular Bioactivity Related to the Cell Line

Map of Molecular Bioactivity Related to the Cell Line Cell Line Protein Compound Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity

Table of Molecular Bioactivities Related to the Cell Line

Protein ID: PT01255, Cytochrome P-450AROM

Protein Info

Compound ID	Compound Name	Compound Formula
CP0329816 Compound Info	1-(imidazol-1-ylmethyl)-3-pent-2-ynoxyxanthen-9-one Show/Hide	C22H18N2O3	1
1	IC50 = 0.01 nM Bioactivity Info	TI LI LO TS
CP0351698 Compound Info	3-(imidazol-1-ylmethyl)-6-pent-2-ynoxyxanthen-9-one Show/Hide	C22H18N2O3	1
1	IC50 = 0.01 nM Bioactivity Info	TI LI LO TS
CP0452027 Compound Info	2-chloro-4-(((6-cyanobiphenyl-3-yl)(4H-1,2,4-triazol-4-yl)amino)methyl)phenyl sulfamate Show/Hide	C22H17ClN6O3S	1
1	IC50 = 0.015 nM Bioactivity Info	TI LI LO TS
CP0472239 Compound Info	4-(((6-cyano-4'-methoxybiphenyl-3-yl)(4H-1,2,4-triazol-4-yl)amino)methyl)phenyl sulfamate Show/Hide	C23H20N6O4S	1
1	IC50 = 0.015 nM Bioactivity Info	TI LI LO TS
CP0404442 Compound Info	2-bromo-4-(((6-cyanobiphenyl-3-yl)(4H-1,2,4-triazol-4-yl)amino)methyl)phenyl sulfamate Show/Hide	C22H17BrN6O3S	1
1	IC50 = 0.018 nM Bioactivity Info	TI LI LO TS
CP0404441 Compound Info	5'-((4-bromobenzyl)(4H-1,2,4-triazol-4-yl)amino)-2'-cyanobiphenyl-4-yl sulfamate Show/Hide	C22H17BrN6O3S	1
1	IC50 = 0.05 nM Bioactivity Info	TI LI LO TS
CP0580118 Compound Info	4-[(6-but-2-ynoxy-1-benzofuran-2-yl)-(1,2,4-triazol-1-yl)methyl]benzonitrile Show/Hide	C22H16N4O2	1
1	IC50 = 0.09 nM Bioactivity Info	TI LI LO TS
CP0524325 Compound Info	2-(5-((1H-1,2,4-triazol-1-yl)methyl)-3'-chloro-4'-hydroxybiphenyl-3-yl)-2-methylpropanenitrile Show/Hide	C19H17ClN4O	1
1	IC50 = 0.1 nM Bioactivity Info	TI LI LO TS
CP0381220 Compound Info	5'-(benzyl(4H-1,2,4-triazol-4-yl)amino)-2'-cyanobiphenyl-4-yl sulfamate Show/Hide	C22H18N6O3S	1
1	IC50 = 0.1 nM Bioactivity Info	TI LI LO TS
CP0570061 Compound Info	4-[(6-methoxy-1-benzofuran-2-yl)(1H-1,2,4-triazol-1-yl)methyl]benzonitrile Show/Hide	C19H14N4O2	1
1	IC50 = 0.11 nM Bioactivity Info	TI LI LO TS
CP0188252 Compound Info	3-CHLORO-2'-CYANO-5'-(1H-1,2,4-TRIAZOL-1-YLMETHYL)BIPHENYL-4-YL SULFAMATE Show/Hide	C16H12ClN5O3S	2
1	IC50 = 0.12 nM Bioactivity Info	TI LI LO TS
2	IC50 = 0.5 nM Bioactivity Info	TI LI LO TS
CP0449272 Compound Info	5-((1H-1,2,4-triazol-1-yl)methyl)-3'-chloro-4'-hydroxybiphenyl-2-carbonitrile Show/Hide	C16H11ClN4O	1
1	IC50 = 0.15 nM Bioactivity Info	TI LI LO TS
CP0378660 Compound Info	4-(((6-cyanobiphenyl-3-yl)(4H-1,2,4-triazol-4-yl)amino)methyl)-2-fluorophenyl sulfamate Show/Hide	C22H17FN6O3S	1
1	IC50 = 0.15 nM Bioactivity Info	TI LI LO TS
CP0075689 Compound Info	1-[(4-fluorophenyl)(6-methoxy-1-benzofuran-2-yl)methyl]-1H-1,2,4-triazole Show/Hide	C18H14FN3O2	1
1	IC50 = 0.15 nM Bioactivity Info	TI LI LO TS
CP0496918 Compound Info	4-{[(4-chloro-3-hydroxyphenyl)methyl](4H-1,2,4-triazol-4-yl)amino}benzonitrile Show/Hide	C16H12ClN5O	1
1	IC50 = 0.18 nM Bioactivity Info	TI LI LO TS
CP0463902 Compound Info	5-((1H-1,2,4-triazol-1-yl)methyl)biphenyl-2-carbonitrile Show/Hide	C16H12N4	1
1	IC50 = 0.2 nM Bioactivity Info	TI LI LO TS
CP0526901 Compound Info	5-((1H-1,2,4-triazol-1-yl)methyl)-4'-hydroxybiphenyl-2-carbonitrile Show/Hide	C16H12N4O	1
1	IC50 = 0.2 nM Bioactivity Info	TI LI LO TS
CP0454391 Compound Info	4-(((6-cyanobiphenyl-3-yl)(4H-1,2,4-triazol-4-yl)amino)methyl)phenyl sulfamate Show/Hide	C22H18N6O3S	1
1	IC50 = 0.21 nM Bioactivity Info	TI LI LO TS
CP0477271 Compound Info	5-((1H-1,2,4-triazol-1-yl)methyl)-4'-chloro-3'-hydroxybiphenyl-2-carbonitrile Show/Hide	C16H11ClN4O	1
1	IC50 = 0.22 nM Bioactivity Info	TI LI LO TS
CP0499344 Compound Info	5-((1H-1,2,4-triazol-1-yl)methyl)-3'-chlorobiphenyl-2-carbonitrile Show/Hide	C16H11ClN4	1
1	IC50 = 0.22 nM Bioactivity Info	TI LI LO TS
CP0429110 Compound Info	[1-bromo-6-[[4-cyano-N-(1,2,4-triazol-4-yl)anilino]methyl]naphthalen-2-yl] sulfamate Show/Hide	C20H15BrN6O3S	1
1	IC50 = 0.25 nM Bioactivity Info	TI LI LO TS
CP0233111 Compound Info	4-[2-(3-chloro-4-hydroxyphenyl)sulfanylethyl-(1,2,4-triazol-4-yl)amino]benzonitrile Show/Hide	C17H14ClN5OS	1
1	IC50 = 0.26 nM Bioactivity Info	TI LI LO TS
CP0395001 Compound Info	4-[2-(4-hydroxyphenyl)sulfanylethyl-(1,2,4-triazol-4-yl)amino]benzonitrile Show/Hide	C17H15N5OS	1
1	IC50 = 0.28 nM Bioactivity Info	TI LI LO TS
CP0374004 Compound Info	3'-((1H-1,2,4-triazol-1-yl)methyl)-3-chloro-5'-(2-cyanopropan-2-yl)biphenyl-4-yl sulfamate Show/Hide	C19H18ClN5O3S	1
1	IC50 = 0.3 nM Bioactivity Info	TI LI LO TS
CP0465602 Compound Info	4-{[(4-hydroxy-3-iodophenyl)methyl](4H-1,2,4-triazol-4-yl)amino}benzonitrile Show/Hide	C16H12IN5O	1
1	IC50 = 0.33 nM Bioactivity Info	TI LI LO TS
CP0390030 Compound Info	5'-((1H-1,2,4-triazol-1-yl)methyl)-4-chloro-2'-cyanobiphenyl-3-yl sulfamate Show/Hide	C16H12ClN5O3S	1
1	IC50 = 0.35 nM Bioactivity Info	TI LI LO TS
CP0571011 Compound Info	2-[(4-fluorophenyl)-(1,2,4-triazol-1-yl)methyl]-1-benzofuran-6-ol Show/Hide	C17H12FN3O2	1
1	IC50 = 0.39 nM Bioactivity Info	TI LI LO TS
CP0475216 Compound Info	4-({[3-hydroxy-4-(trifluoromethyl)phenyl]methyl}(4H-1,2,4-triazol-4-yl)amino)benzonitrile Show/Hide	C17H12F3N5O	1
1	IC50 = 0.4 nM Bioactivity Info	TI LI LO TS
CP0434077 Compound Info	[4-[2-[4-cyano-N-(1,2,4-triazol-4-yl)anilino]ethylsulfanyl]phenyl] sulfamate Show/Hide	C17H16N6O3S2	1
1	IC50 = 0.42 nM Bioactivity Info	TI LI LO TS
CP0380336 Compound Info	[2-chloro-4-[2-[4-cyano-N-(1,2,4-triazol-4-yl)anilino]ethylsulfanyl]phenyl] sulfamate Show/Hide	C17H15ClN6O3S2	1
1	IC50 = 0.45 nM Bioactivity Info	TI LI LO TS
CP0576135 Compound Info	1-[(4-chlorophenyl)-(6-ethoxy-1-benzofuran-2-yl)methyl]-1,2,4-triazole Show/Hide	C19H16ClN3O2	1
1	IC50 = 0.46 nM Bioactivity Info	TI LI LO TS
CP0404443 Compound Info	4-(((6-cyano-4'-fluorobiphenyl-3-yl)(4H-1,2,4-triazol-4-yl)amino)methyl)phenyl sulfamate Show/Hide	C22H17FN6O3S	1
1	IC50 = 0.47 nM Bioactivity Info	TI LI LO TS
CP0167002 Compound Info	1-[(4-chlorophenyl)(6-methoxy-1-benzofuran-2-yl)methyl]-1H-1,2,4-triazole Show/Hide	C18H14ClN3O2	1
1	IC50 = 0.47 nM Bioactivity Info	TI LI LO TS
CP0395993 Compound Info	4-{[(4-bromophenyl)methyl](4H-1,2,4-triazol-4-yl)amino}benzonitrile Show/Hide	C16H12BrN5	1
1	IC50 = 0.5 nM Bioactivity Info	TI LI LO TS
CP0406541 Compound Info	4-{[(4-bromo-3-hydroxyphenyl)methyl](4H-1,2,4-triazol-4-yl)amino}benzonitrile Show/Hide	C16H12BrN5O	1
1	IC50 = 0.5 nM Bioactivity Info	TI LI LO TS
CP0375647 Compound Info	5'-((1H-1,2,4-triazol-1-yl)methyl)-2'-cyanobiphenyl-4-yl dimethylsulfamate Show/Hide	C18H17N5O3S	1
1	IC50 = 0.5 nM Bioactivity Info	TI LI LO TS
CP0502665 Compound Info	2-(5-((1H-1,2,4-triazol-1-yl)methyl)biphenyl-3-yl)-2-methylpropanenitrile Show/Hide	C19H18N4	1
1	IC50 = 0.5 nM Bioactivity Info	TI LI LO TS
CP0496919 Compound Info	4-{[(3-chloro-4-hydroxy-5-methoxyphenyl)methyl](4H-1,2,4-triazol-4-yl)amino}benzonitrile Show/Hide	C17H14ClN5O2	1
1	IC50 = 0.51 nM Bioactivity Info	TI LI LO TS
CP0374817 Compound Info	[4-[3-[4-cyano-N-(1,2,4-triazol-4-yl)anilino]propylsulfanyl]phenyl] sulfamate Show/Hide	C18H18N6O3S2	1
1	IC50 = 0.51 nM Bioactivity Info	TI LI LO TS
CP0570060 Compound Info	1-[(4-fluorophenyl)-(6-pent-2-ynoxy-1-benzofuran-2-yl)methyl]-1,2,4-triazole Show/Hide	C22H18FN3O2	1
1	IC50 = 0.51 nM Bioactivity Info	TI LI LO TS
CP0571095 Compound Info	1-[(6-but-2-ynoxy-1-benzofuran-2-yl)-(4-chlorophenyl)methyl]-1,2,4-triazole Show/Hide	C21H16ClN3O2	1
1	IC50 = 0.53 nM Bioactivity Info	TI LI LO TS
CP0576871 Compound Info	4-[(6-Hydroxybenzofuran-2-yl)-[1,2,4]triazol-1-ylmethyl]benzonitrile Show/Hide	C18H12N4O2	1
1	IC50 = 0.56 nM Bioactivity Info	TI LI LO TS
CP0406542 Compound Info	4-{[(4-fluoro-3-hydroxyphenyl)methyl](4H-1,2,4-triazol-4-yl)amino}benzonitrile Show/Hide	C16H12FN5O	1
1	IC50 = 0.6 nM Bioactivity Info	TI LI LO TS
CP0540281 Compound Info	4-[(R)-(3-bromo-4-hydroxyphenyl)(1H-1,2,4-triazol-1-yl)methyl]benzonitrile Show/Hide	C16H11BrN4O	1
1	IC50 = 0.6 nM Bioactivity Info	TI LI LO TS
CP0055110 Compound Info	4,4 -(1H-1,2,4-triazol-1-ylmethanediyl)dibenzonitrile Show/Hide	C17H11N5	2
1	IC50 = 0.7 nM Bioactivity Info	TI LI LO TS
2	IC50 = 0.89 nM Bioactivity Info	TI LI LO TS
CP0569987 Compound Info	4-[(6-pent-2-ynoxy-1-benzofuran-2-yl)-(1,2,4-triazol-1-yl)methyl]benzonitrile Show/Hide	C23H18N4O2	1
1	IC50 = 0.72 nM Bioactivity Info	TI LI LO TS
CP0380338 Compound Info	[4-[5-[4-cyano-N-(1,2,4-triazol-4-yl)anilino]pentylsulfanyl]phenyl] sulfamate Show/Hide	C20H22N6O3S2	1
1	IC50 = 0.73 nM Bioactivity Info	TI LI LO TS
CP0395886 Compound Info	4-(((4',6-dicyanobiphenyl-3-yl)(4H-1,2,4-triazol-4-yl)amino)methyl)phenyl sulfamate Show/Hide	C23H17N7O3S	1
1	IC50 = 0.75 nM Bioactivity Info	TI LI LO TS
CP0445734 Compound Info	(5-{[(4-cyanophenyl)(4H-1,2,4-triazol-4-yl)amino]methyl}-2-fluorophenyl) sulfamate Show/Hide	C16H13FN6O3S	1
1	IC50 = 0.77 nM Bioactivity Info	TI LI LO TS
CP0351697 Compound Info	4-(imidazol-1-ylmethyl)-2-pent-2-ynoxyxanthen-9-one Show/Hide	C22H18N2O3	1
1	IC50 = 0.77 nM Bioactivity Info	TI LI LO TS
CP0577489 Compound Info	2-[(4-Chlorophenyl)-[1,2,4]triazol-1-ylmethyl]benzofuran-6-ol Show/Hide	C17H12ClN3O2	1
1	IC50 = 0.79 nM Bioactivity Info	TI LI LO TS
CP0374009 Compound Info	6-((1H-1,2,4-triazol-1-yl)methyl)-3'-chloro-4'-hydroxybiphenyl-3-carbonitrile Show/Hide	C16H11ClN4O	1
1	IC50 = 0.8 nM Bioactivity Info	TI LI LO TS
CP0259310 Compound Info	(2-bromo-4-{[(4-cyanophenyl)(4H-1,2,4-triazol-4-yl)amino]methyl}phenyl) sulfamate Show/Hide	C16H13BrN6O3S	1
1	IC50 = 0.82 nM Bioactivity Info	TI LI LO TS
CP0480297 Compound Info	4-({[4-hydroxy-3-(trifluoromethyl)phenyl]methyl}(4H-1,2,4-triazol-4-yl)amino)benzonitrile Show/Hide	C17H12F3N5O	1
1	IC50 = 0.88 nM Bioactivity Info	TI LI LO TS
CP0465607 Compound Info	(2-chloro-5-{[(4-cyanophenyl)(4H-1,2,4-triazol-4-yl)amino]methyl}phenyl) sulfamate Show/Hide	C16H13ClN6O3S	1
1	IC50 = 0.92 nM Bioactivity Info	TI LI LO TS
CP0571010 Compound Info	1-[(4-chlorophenyl)-(6-prop-2-ynoxy-1-benzofuran-2-yl)methyl]-1,2,4-triazole Show/Hide	C20H14ClN3O2	1
1	IC50 = 1.03 nM Bioactivity Info	TI LI LO TS
CP0496921 Compound Info	4-{[(3-bromo-4-hydroxyphenyl)methyl](4H-1,2,4-triazol-4-yl)amino}benzonitrile Show/Hide	C16H12BrN5O	1
1	IC50 = 1.1 nM Bioactivity Info	TI LI LO TS
CP0465601 Compound Info	4-{[(3-hydroxy-4-methoxyphenyl)methyl](4H-1,2,4-triazol-4-yl)amino}benzonitrile Show/Hide	C17H15N5O2	1
1	IC50 = 1.2 nM Bioactivity Info	TI LI LO TS
CP0903148 Compound Info	(R)-6-((4-chlorophenyl)(1H-1,2,4-triazol-1-yl)methyl)-1-methyl-1H-benzo[d][1,2,3]triazole Show/Hide	C16H13ClN6	1
1	IC50 = 1.38 nM Bioactivity Info	TI LI LO TS
CP0457964 Compound Info	(4-{[(4-cyanophenyl)(4H-1,2,4-triazol-4-yl)amino]methyl}-2-iodophenyl) sulfamate Show/Hide	C16H13IN6O3S	1
1	IC50 = 1.5 nM Bioactivity Info	TI LI LO TS
CP0046488 Compound Info	2-[3-(1-cyano-1-methylethyl)-5-(1H-1,2,4-triazol-1-ylmethyl)phenyl]-2-methylpropanenitrile Show/Hide	C17H19N5	1
1	IC50 = 1.5 nM Bioactivity Info	TI LI LO TS
CP0374008 Compound Info	6-((1H-1,2,4-triazol-1-yl)methyl)biphenyl-3-carbonitrile Show/Hide	C16H12N4	1
1	IC50 = 1.7 nM Bioactivity Info	TI LI LO TS
CP0401140 Compound Info	4-[(3-bromo-4-hydroxyphenyl)(1H-1,2,4-triazol-1-yl)methyl]benzonitrile Show/Hide	C16H11BrN4O	1
1	IC50 = 1.8 nM Bioactivity Info	TI LI LO TS
CP0390031 Compound Info	2'-((1H-1,2,4-triazol-1-yl)methyl)-3-chloro-5'-cyanobiphenyl-4-yl sulfamate Show/Hide	C16H12ClN5O3S	1
1	IC50 = 1.9 nM Bioactivity Info	TI LI LO TS
CP0374003 Compound Info	5'-((1H-1,2,4-triazol-1-yl)methyl)-2'-cyanobiphenyl-4-yl sulfamate Show/Hide	C16H13N5O3S	1
1	IC50 = 2 nM Bioactivity Info	TI LI LO TS
CP0579861 Compound Info	1-[(4-chlorophenyl)-(5-methoxy-1-benzofuran-2-yl)methyl]-1,2,4-triazole Show/Hide	C18H14ClN3O2	1
1	IC50 = 2.01 nM Bioactivity Info	TI LI LO TS
CP0207557 Compound Info	[1-chloro-6-[[4-cyano-N-(1,2,4-triazol-4-yl)anilino]methyl]naphthalen-2-yl] sulfamate Show/Hide	C20H15ClN6O3S	1
1	IC50 = 2.1 nM Bioactivity Info	TI LI LO TS
CP0429111 Compound Info	[3-[2-[4-cyano-N-(1,2,4-triazol-4-yl)anilino]ethyl]-1-methylindol-5-yl] sulfamate Show/Hide	C20H19N7O3S	1
1	IC50 = 2.3 nM Bioactivity Info	TI LI LO TS
CP0390027 Compound Info	5'-((1H-1,2,4-triazol-1-yl)methyl)-3-chloro-2'-cyanobiphenyl-4-yl dimethylsulfamate Show/Hide	C18H16ClN5O3S	1
1	IC50 = 2.4 nM Bioactivity Info	TI LI LO TS
CP0496922 Compound Info	4-{[(3-chloro-4-hydroxyphenyl)methyl](4H-1,2,4-triazol-4-yl)amino}benzonitrile Show/Hide	C16H12ClN5O	1
1	IC50 = 2.5 nM Bioactivity Info	TI LI LO TS
CP0068046 Compound Info	(rac)-6-((4-chlorophenyl)(1H-1,2,4-triazol-1-yl)methyl)-1-methyl-1H-benzo[d][1,2,3]triazole Show/Hide	C16H13ClN6	1
1	IC50 = 2.59 nM Bioactivity Info	TI LI LO TS
CP0380339 Compound Info	[1-[2-[4-cyano-N-(1,2,4-triazol-4-yl)anilino]ethyl]indol-5-yl] sulfamate Show/Hide	C19H17N7O3S	1
1	IC50 = 2.7 nM Bioactivity Info	TI LI LO TS
CP0577490 Compound Info	1-[(4-chlorophenyl)-(6-pent-2-ynoxy-1-benzofuran-2-yl)methyl]-1,2,4-triazole Show/Hide	C22H18ClN3O2	1
1	IC50 = 2.76 nM Bioactivity Info	TI LI LO TS
CP0505376 Compound Info	4-{[(3-hydroxyphenyl)methyl](4H-1,2,4-triazol-4-yl)amino}benzonitrile Show/Hide	C16H13N5O	1
1	IC50 = 2.8 nM Bioactivity Info	TI LI LO TS
CP0522665 Compound Info	4-{[(4-hydroxy-3-methoxyphenyl)methyl](4H-1,2,4-triazol-4-yl)amino}benzonitrile Show/Hide	C17H15N5O2	1
1	IC50 = 2.8 nM Bioactivity Info	TI LI LO TS
CP0465604 Compound Info	(2-chloro-4-{[(4-cyanophenyl)(4H-1,2,4-triazol-4-yl)amino]methyl}-6-methoxyphenyl) sulfamate Show/Hide	C17H15ClN6O4S	1
1	IC50 = 2.9 nM Bioactivity Info	TI LI LO TS
CP0493668 Compound Info	4-{[(3-fluoro-4-hydroxyphenyl)methyl](4H-1,2,4-triazol-4-yl)amino}benzonitrile Show/Hide	C16H12FN5O	1
1	IC50 = 2.9 nM Bioactivity Info	TI LI LO TS
CP0395022 Compound Info	Letrozole derivative, 40 Show/Hide	C16H12BrN5O3S	1
1	IC50 = 3 nM Bioactivity Info	TI LI LO TS
CP0380337 Compound Info	Letrozole derivative, 40a R-(+) Show/Hide	C16H12BrN5O3S	1
1	IC50 = 3.2 nM Bioactivity Info	TI LI LO TS
CP0919446 Compound Info	(S)-4-(5,6,7,8-tetrahydroimidazo[1,5-a]pyridin-5-yl)benzonitrile hydrochloride Show/Hide	C14H14ClN3	1
1	IC50 = 3.2 nM Bioactivity Info	TI LI LO TS
CP0540280 Compound Info	4-[(S)-(3-bromo-4-hydroxyphenyl)(1H-1,2,4-triazol-1-yl)methyl]benzonitrile Show/Hide	C16H11BrN4O	1
1	IC50 = 3.4 nM Bioactivity Info	TI LI LO TS
CP0445733 Compound Info	(2-bromo-5-{[(4-cyanophenyl)(4H-1,2,4-triazol-4-yl)amino]methyl}phenyl) sulfamate Show/Hide	C16H13BrN6O3S	1
1	IC50 = 3.9 nM Bioactivity Info	TI LI LO TS
CP0434079 Compound Info	[3-[2-[4-cyano-N-(1,2,4-triazol-4-yl)anilino]ethyl]-1-benzofuran-5-yl] sulfamate Show/Hide	C19H16N6O4S	1
1	IC50 = 4 nM Bioactivity Info	TI LI LO TS
CP0551683 Compound Info	1-[(6-but-2-ynoxy-1-benzofuran-2-yl)-(4-fluorophenyl)methyl]-1,2,4-triazole Show/Hide	C21H16FN3O2	1
1	IC50 = 4.1 nM Bioactivity Info	TI LI LO TS
CP0375635 Compound Info	4-((1H-1,2,4-triazol-1-yl)methyl)biphenyl-2-carbonitrile Show/Hide	C16H12N4	1
1	IC50 = 4.6 nM Bioactivity Info	TI LI LO TS
CP0374677 Compound Info	[6-[[4-cyano-N-(1,2,4-triazol-4-yl)anilino]methyl]-5,6,7,8-tetrahydronaphthalen-2-yl] sulfamate Show/Hide	C20H20N6O3S	1
1	IC50 = 5.2 nM Bioactivity Info	TI LI LO TS
CP0476395 Compound Info	4-[(3-chloro-4-hydroxyphenyl)(1H-1,2,4-triazol-1-yl)methyl]benzonitrile Show/Hide	C16H11ClN4O	1
1	IC50 = 5.5 nM Bioactivity Info	TI LI LO TS
CP0562829 Compound Info	2-[(4-chlorophenyl)-(1,2,4-triazol-1-yl)methyl]-1-benzofuran-5-ol Show/Hide	C17H12ClN3O2	1
1	IC50 = 5.67 nM Bioactivity Info	TI LI LO TS
CP0390033 Compound Info	2-(5-((1H-1,2,4-triazol-1-yl)methyl)-4'-hydroxybiphenyl-3-yl)-2-methylpropanenitrile Show/Hide	C19H18N4O	1
1	IC50 = 6 nM Bioactivity Info	TI LI LO TS
CP0423268 Compound Info	4-[(4-hydroxyphenyl)(1H-1,2,4-triazol-1-yl)methyl]benzonitrile Show/Hide	C16H12N4O	1
1	IC50 = 7.2 nM Bioactivity Info	TI LI LO TS
CP0522664 Compound Info	4-{[(3,5-dichloro-4-hydroxyphenyl)methyl](4H-1,2,4-triazol-4-yl)amino}benzonitrile Show/Hide	C16H11Cl2N5O	1
1	IC50 = 7.6 nM Bioactivity Info	TI LI LO TS
CP0508041 Compound Info	2-bromo-4-[(3-bromo-4-hydroxyphenyl)(1H-1,2,4-triazol-1-yl)methyl]phenol Show/Hide	C15H11Br2N3O2	1
1	IC50 = 10 nM Bioactivity Info	TI LI LO TS
CP0366361 Compound Info	(6R,8R,9S,10R,13S,14S)-10,13-dimethyl-6-pent-2-ynoxy-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthrene-3,17-dione Show/Hide	C24H30O3	1
1	IC50 = 11.8 nM Bioactivity Info	TI LI LO TS
CP0445732 Compound Info	(5-{[(4-cyanophenyl)(4H-1,2,4-triazol-4-yl)amino]methyl}-2-methoxyphenyl) sulfamate Show/Hide	C17H16N6O4S	1
1	IC50 = 12 nM Bioactivity Info	TI LI LO TS
CP0504217 Compound Info	Letrozole derivative, 34 Show/Hide	C16H12ClN5O3S	1
1	IC50 = 12 nM Bioactivity Info	TI LI LO TS
CP0387897 Compound Info	Letrozole derivative, 28 Show/Hide	C16H13N5O3S	1
1	IC50 = 13 nM Bioactivity Info	TI LI LO TS
CP0374673 Compound Info	Letrozole derivative, 40b S-(-) Show/Hide	C16H12BrN5O3S	1
1	IC50 = 14.3 nM Bioactivity Info	TI LI LO TS
CP0460994 Compound Info	3-((1H-1,2,4-triazol-1-yl)methyl)-3'-hydroxybiphenyl-4-carbonitrile Show/Hide	C16H12N4O	1
1	IC50 = 14.4 nM Bioactivity Info	TI LI LO TS
CP0395000 Compound Info	4-[3-(4-hydroxyphenyl)sulfonylpropyl-(1,2,4-triazol-4-yl)amino]benzonitrile Show/Hide	C18H17N5O3S	1
1	IC50 = 15 nM Bioactivity Info	TI LI LO TS
CP0460989 Compound Info	3'-((1H-1,2,4-triazol-1-yl)methyl)-5'-(2-cyanopropan-2-yl)biphenyl-4-yl sulfamate Show/Hide	C19H19N5O3S	1
1	IC50 = 17.5 nM Bioactivity Info	TI LI LO TS
CP0390032 Compound Info	5-((1H-1,2,4-triazol-1-yl)methyl)-4'-fluorobiphenyl-3-carbonitrile Show/Hide	C16H11FN4	1
1	IC50 = 19 nM Bioactivity Info	TI LI LO TS
CP0569217 Compound Info	1-[(4-chlorophenyl)-(5-pent-2-ynoxy-1-benzofuran-2-yl)methyl]-1,2,4-triazole Show/Hide	C22H18ClN3O2	1
1	IC50 = 21.05 nM Bioactivity Info	TI LI LO TS
CP0480298 Compound Info	4-{[(4-hydroxyphenyl)methyl](4H-1,2,4-triazol-4-yl)amino}benzonitrile Show/Hide	C16H13N5O	1
1	IC50 = 23 nM Bioactivity Info	TI LI LO TS
CP0496920 Compound Info	5-{[(4-cyanophenyl)(4H-1,2,4-triazol-4-yl)amino]methyl}-2-hydroxybenzonitrile Show/Hide	C17H12N6O	1
1	IC50 = 24 nM Bioactivity Info	TI LI LO TS
CP0502664 Compound Info	5-((1H-1,2,4-triazol-1-yl)methyl)-3'-chloro-4'-hydroxybiphenyl-3-carbonitrile Show/Hide	C16H11ClN4O	1
1	IC50 = 24 nM Bioactivity Info	TI LI LO TS
CP0465606 Compound Info	(2-cyano-4-{[(4-cyanophenyl)(4H-1,2,4-triazol-4-yl)amino]methyl}phenyl) sulfamate Show/Hide	C17H13N7O3S	1
1	IC50 = 27 nM Bioactivity Info	TI LI LO TS
CP0374674 Compound Info	(S)-VOROZOLE Show/Hide	C16H13ClN6	2
1	IC50 = 29 nM Bioactivity Info	TI LI LO TS
2	IC50 = 44.2 nM Bioactivity Info	TI LI LO TS
CP0374680 Compound Info	[4-[(3-methylbenzotriazol-5-yl)-(1,2,4-triazol-1-yl)methyl]phenyl] sulfamate Show/Hide	C16H15N7O3S	1
1	IC50 = 29 nM Bioactivity Info	TI LI LO TS
CP0381213 Compound Info	5-((1H-1,2,4-triazol-1-yl)methyl)biphenyl-3-carbonitrile Show/Hide	C16H12N4	1
1	IC50 = 29.3 nM Bioactivity Info	TI LI LO TS
CP0579132 Compound Info	4-[(5-chloro-1-benzofuran-2-yl)-(1,2,4-triazol-1-yl)methyl]phenol Show/Hide	C17H12ClN3O2	1
1	IC50 = 30.25 nM Bioactivity Info	TI LI LO TS
CP0456203 Compound Info	[6-[[4-cyano-N-(1,2,4-triazol-4-yl)anilino]methyl]naphthalen-2-yl] sulfamate Show/Hide	C20H16N6O3S	1
1	IC50 = 31 nM Bioactivity Info	TI LI LO TS
CP0505377 Compound Info	(4-{[(4-cyanophenyl)(4H-1,2,4-triazol-4-yl)amino]methyl}-2-methoxyphenyl) sulfamate Show/Hide	C17H16N6O4S	1
1	IC50 = 42 nM Bioactivity Info	TI LI LO TS
CP0423414 Compound Info	(2-bromo-4-{[3-bromo-4-(sulfamoyloxy)phenyl](1H-1,2,4-triazol-1-yl)methyl}phenyl) sulfamate Show/Hide	C15H13Br2N5O6S2	1
1	IC50 = 43 nM Bioactivity Info	TI LI LO TS
CP0084477 Compound Info	Aromasin Show/Hide	C20H24O2	1
1	IC50 = 50.1 nM Bioactivity Info	TI LI LO TS
CP0374006 Compound Info	5-((1H-1,2,4-triazol-1-yl)methyl)biphenyl-3,4'-dicarbonitrile Show/Hide	C17H11N5	1
1	IC50 = 52 nM Bioactivity Info	TI LI LO TS
CP0390029 Compound Info	3'-((1H-1,2,4-triazol-1-yl)methyl)-3-chlorobiphenyl-4-yl sulfamate Show/Hide	C15H13ClN4O3S	1
1	IC50 = 70 nM Bioactivity Info	TI LI LO TS
CP0518876 Compound Info	3-((1H-1,2,4-triazol-1-yl)methyl)-3'-chloro-4'-hydroxybiphenyl-4-carbonitrile Show/Hide	C16H11ClN4O	1
1	IC50 = 74 nM Bioactivity Info	TI LI LO TS
CP0417936 Compound Info	3'-((1H-1,2,4-triazol-1-yl)methyl)-3-chloro-5'-cyanobiphenyl-4-yl sulfamate Show/Hide	C16H12ClN5O3S	1
1	IC50 = 80 nM Bioactivity Info	TI LI LO TS
CP0458613 Compound Info	(3-{[3-(sulfamoyloxy)phenyl](1H-1,2,4-triazol-1-yl)methyl}phenyl) sulfamate Show/Hide	C15H15N5O6S2	1
1	IC50 = 99 nM Bioactivity Info	TI LI LO TS
CP0395885 Compound Info	(4-{[(4-cyanophenyl)(4H-1,2,4-triazol-4-yl)amino]methyl}phenyl) sulfamate Show/Hide	C16H14N6O3S	1
1	IC50 = 100 nM Bioactivity Info	TI LI LO TS
CP0381214 Compound Info	5-((1H-1,2,4-triazol-1-yl)methyl)-4'-hydroxybiphenyl-3-carbonitrile Show/Hide	C16H12N4O	1
1	IC50 = 112 nM Bioactivity Info	TI LI LO TS
CP0375644 Compound Info	3'-((1H-1,2,4-triazol-1-yl)methyl)-3-chloro-4'-cyanobiphenyl-4-yl sulfamate Show/Hide	C16H12ClN5O3S	1
1	IC50 = 146 nM Bioactivity Info	TI LI LO TS
CP0427916 Compound Info	4-{[(2,3,5,6-tetrafluoro-4-hydroxyphenyl)methyl](4H-1,2,4-triazol-4-yl)amino}benzonitrile Show/Hide	C16H9F4N5O	1
1	IC50 = 159 nM Bioactivity Info	TI LI LO TS
CP0504218 Compound Info	5-[(3-hydroxy-4-methoxyphenyl)(1H-1,2,4-triazol-1-yl)methyl]-2-methoxyphenol Show/Hide	C17H17N3O4	1
1	IC50 = 169 nM Bioactivity Info	TI LI LO TS
CP0450388 Compound Info	3'-((1H-1,2,4-triazol-1-yl)methyl)-4'-cyanobiphenyl-4-yl sulfamate Show/Hide	C16H13N5O3S	1
1	IC50 = 176 nM Bioactivity Info	TI LI LO TS
CP0423270 Compound Info	4-[(4-hydroxyphenyl)(1H-1,2,4-triazol-1-yl)methyl]phenol Show/Hide	C15H13N3O2	1
1	IC50 = 178 nM Bioactivity Info	TI LI LO TS
CP0430969 Compound Info	1-(biphenyl-3-ylmethyl)-1H-1,2,4-triazole Show/Hide	C15H13N3	1
1	IC50 = 210 nM Bioactivity Info	TI LI LO TS
CP0489823 Compound Info	4-[(4-hydroxy-3-methoxyphenyl)(1H-1,2,4-triazol-1-yl)methyl]-2-methoxyphenol Show/Hide	C17H17N3O4	1
1	IC50 = 215 nM Bioactivity Info	TI LI LO TS
CP0390041 Compound Info	3'-((1H-1,2,4-triazol-1-yl)methyl)biphenyl-4-yl sulfamate Show/Hide	C15H14N4O3S	1
1	IC50 = 275 nM Bioactivity Info	TI LI LO TS
CP0499343 Compound Info	3'-((1H-1,2,4-triazol-1-yl)methyl)-5'-cyanobiphenyl-4-yl sulfamate Show/Hide	C16H13N5O3S	1
1	IC50 = 280 nM Bioactivity Info	TI LI LO TS
CP0384442 Compound Info	4'-((1H-1,2,4-triazol-1-yl)methyl)-2'-cyanobiphenyl-4-yl sulfamate Show/Hide	C16H13N5O3S	1
1	IC50 = 284 nM Bioactivity Info	TI LI LO TS
CP0055053 Compound Info	6-oxo-6,7,8,9,10,11-hexahydrocyclohepta[c]chromen-3-yl sulfamate Show/Hide	C14H15NO5S	1
1	IC50 = 300 nM Bioactivity Info	TI LI LO TS
CP0417946 Compound Info	4-((1H-1,2,4-triazol-1-yl)methyl)-3'-chloro-4'-hydroxybiphenyl-2-carbonitrile Show/Hide	C16H11ClN4O	1
1	IC50 = 380 nM Bioactivity Info	TI LI LO TS
CP0390040 Compound Info	4'-((1H-1,2,4-triazol-1-yl)methyl)-3-chloro-2'-cyanobiphenyl-4-yl sulfamate Show/Hide	C16H12ClN5O3S	1
1	IC50 = 571 nM Bioactivity Info	TI LI LO TS
CP0873675 Compound Info	FADROZOLE HYDROCHLORIDE Show/Hide	C14H14ClN3	1
1	IC50 = 680 nM Bioactivity Info	TI LI LO TS
CP0374007 Compound Info	4-((1H-1,2,4-Triazol-1-yl)methyl)-4'-hydroxybiphenyl-2-carbonitrile Show/Hide	C16H12N4O	1
1	IC50 = 920 nM Bioactivity Info	TI LI LO TS
CP0456186 Compound Info	3-[(3-hydroxyphenyl)(1H-1,2,4-triazol-1-yl)methyl]phenol Show/Hide	C15H13N3O2	1
1	IC50 = 2457 nM Bioactivity Info	TI LI LO TS
CP0428644 Compound Info	(4-{[4-(sulfamoyloxy)phenyl](1H-1,2,4-triazol-1-yl)methyl}phenyl) sulfamate Show/Hide	C15H15N5O6S2	1
1	IC50 = 3044 nM Bioactivity Info	TI LI LO TS
CP0551681 Compound Info	1-[(5-chloro-1-benzofuran-2-yl)-(4-methoxyphenyl)methyl]-1,2,4-triazole Show/Hide	C18H14ClN3O2	1
1	IC50 > 1000 nM Bioactivity Info	TI LI LO TS
CP0551682 Compound Info	1-[(5-chloro-1-benzofuran-2-yl)-(4-pent-2-ynoxyphenyl)methyl]-1,2,4-triazole Show/Hide	C22H18ClN3O2	1
1	IC50 > 1000 nM Bioactivity Info	TI LI LO TS

Protein ID: PT01689, Steryl-sulfatase

Protein Info

Protein family and CMB statistics Related to the Cell Line

Cell Lines Derived from the same Tissue Source (Brain)

Cell Line Name		Organism	Disease
TS603	Cell Line Info	Homo sapiens (Human)	Anaplastic oligodendroglioma
H4	Cell Line Info	Homo sapiens (Human)	Astrocytoma
1321N1	Cell Line Info	Homo sapiens (Human)	Astrocytoma
SNB-19	Cell Line Info	Homo sapiens (Human)	Astrocytoma
U-251MG	Cell Line Info	Homo sapiens (Human)	Astrocytoma
U-373MG ATCC	Cell Line Info	Homo sapiens (Human)	Astrocytoma
LN-308	Cell Line Info	Homo sapiens (Human)	Astrocytoma
CCF-STTG1	Cell Line Info	Homo sapiens (Human)	Astrocytoma
LN-319	Cell Line Info	Homo sapiens (Human)	Astrocytoma
P2X7-1321N1	Cell Line Info	Homo sapiens (Human)	Astrocytoma
MDA-MB-361	Cell Line Info	Homo sapiens (Human)	Breast adenocarcinoma
D3 [Human glioblastoma]	Cell Line Info	Homo sapiens (Human)	Glioblastoma
LN-229	Cell Line Info	Homo sapiens (Human)	Glioblastoma
LN-18	Cell Line Info	Homo sapiens (Human)	Glioblastoma
A-172	Cell Line Info	Homo sapiens (Human)	Glioblastoma
UC-11MG	Cell Line Info	Homo sapiens (Human)	Glioblastoma
T98G	Cell Line Info	Homo sapiens (Human)	Glioblastoma
LN229-V6R	Cell Line Info	Homo sapiens (Human)	Glioblastoma
SF539	Cell Line Info	Homo sapiens (Human)	Gliosarcoma
MED1	Cell Line Info	Homo sapiens (Human)	Medulloblastoma, non-WNT/non-SHH, group 4
Kelly	Cell Line Info	Homo sapiens (Human)	Neuroblastoma
PFSK-1	Cell Line Info	Homo sapiens (Human)	Primitive neuroectodermal tumor
DU145	Cell Line Info	Homo sapiens (Human)	Prostate carcinoma
DU145-TxR	Cell Line Info	Homo sapiens (Human)	Prostate carcinoma
GL261	Cell Line Info	Mus musculus (Mouse)	Mouse glioblastoma
C6	Cell Line Info	Rattus norvegicus (Rat)	Rat malignant glioma
C6-BU-1	Cell Line Info	Rattus norvegicus (Rat)	Rat malignant glioma
RG2	Cell Line Info	Rattus norvegicus (Rat)	Rat malignant glioma
ReNcell VM	Cell Line Info	Homo sapiens (Human)	-
hCMEC/D3	Cell Line Info	Homo sapiens (Human)	-
BV-2	Cell Line Info	Mus musculus (Mouse)	-
C17.2	Cell Line Info	Mus musculus (Mouse)	-
ScGT1	Cell Line Info	Mus musculus (Mouse)	-
bEnd.4	Cell Line Info	Mus musculus (Mouse)	-
N39	Cell Line Info	Mus musculus (Mouse)	-
GT1-7	Cell Line Info	Mus musculus (Mouse)	-
N27-A	Cell Line Info	Rattus norvegicus (Rat)	-
RBE4	Cell Line Info	Rattus norvegicus (Rat)	-

Cite

About MolBiC

Correspondence

Prof. Feng ZHU

Prof. Leo, Lianyi Han