General Information of the Compound
Compound ID
CP0508041
Compound Name
2-bromo-4-[(3-bromo-4-hydroxyphenyl)(1H-1,2,4-triazol-1-yl)methyl]phenol
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Structure
Formula
C15H11Br2N3O2
Molecular Weight
425.08
Canonical SMILES
Oc1ccc(cc1Br)C(c1ccc(O)c(Br)c1)n1cncn1
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InChI
InChI=1S/C15H11Br2N3O2/c16-11-5-9(1-3-13(11)21)15(20-8-18-7-19-20)10-2-4-14(22)12(17)6-10/h1-8,15,21-22H
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InChIKey
ZRCUDRUAGLSNHH-UHFFFAOYSA-N
Physicochemical Property
logP
3.852
Rotatable Bonds
3
Heavy Atom Count
22
Polar Areas
71.17
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
5
Complexity
22

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 21976892
SID: 53799937
ChEMBL ID
CHEMBL480451
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01255, Aromatase
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000208 JEG-3 Homo sapiens (Human)  1
1
IC50 = 10 nM
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