Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-[3-(1-cyano-1-methylethyl)-5-(1H-1,2,4-triazol-1-ylmethyl)phenyl]-2-methylpropanenitrile
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 PubChem ID
CID: 2187
SID: 14751420
Canonical SMILES
CC(C)(C#N)c1cc(Cn2cncn2)cc(c1)C(C)(C)C#N
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Compound Formula C17H19N5
Compound Structure
Protein Name
 Protein Info 
Aromatase
Protein Classification
Enzyme
>
Cytochrome P450
>
Cytochrome P450 family 19
>
Cytochrome P450 family 19A
>
Cytochrome P450 19A1
Uniprot ID
P11511
Gene Name
CYP19A1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000208 JEG-3
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 1.5 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 1.5 nM
2 IC50 = 8 nM
3 IC50 = 12 nM
4 Ki = 0.13 nM