General Information of the Cell Line
Cell Line ID
CL000441
Cell Line Name
UC-11MG
Synonyms
UC-11 MG
UC11MG
Category
Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_M421
Tissue Information
Brain
Disease
Glioblastoma (NCIt: C3058)
Glioblastoma (ORDO: Orphanet_360)
Map of Molecular Bioactivity Related to the Cell Line
Map of Molecular Bioactivity Related to the Cell Line

Cell Line
Protein
Compound

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Cell Line
Protein ID: PT01410, Substance-P receptor
 Protein Info 
Compound ID Compound Name Compound Formula
CP0449621
 Compound Info 
2-Bromomethyl-4-phenyl-quinoline-3-carboxylic acid 3,5-bis-trifluoromethyl-benzylamide
   Show/Hide
C26H17BrF6N2O
  1
1
IC50 = 0.01 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0509118
 Compound Info 
2-Methylaminomethyl-4-phenyl-quinoline-3-carboxylic acid 3,5-bis-trifluoromethyl-benzylamide
   Show/Hide
C27H21F6N3O
  1
1
IC50 = 0.011 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0381056
 Compound Info 
4-Phenyl-quinoline-3-carboxylic acid (3,5-bis-trifluoromethyl-benzyl)-methyl-amide
   Show/Hide
C26H18F6N2O
  1
1
IC50 = 0.03 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0418810
 Compound Info 
2-Methyl-4-phenyl-quinoline-3-carboxylic acid 3,5-bis-trifluoromethyl-benzylamide
   Show/Hide
C26H18F6N2O
  2
1
IC50 = 0.075 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
IC50 = 3900 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0049105
 Compound Info 
(SP)Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met-NH2
   Show/Hide
C63H98N18O13S
  1
1
IC50 = 0.12 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0418811
 Compound Info 
2-Dimethylaminomethyl-4-phenyl-quinoline-3-carboxylic acid 3,5-bis-trifluoromethyl-benzylamide
   Show/Hide
C28H23F6N3O
  2
1
IC50 = 0.22 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
IC50 = 11 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0363940
 Compound Info 
(2R,3R)-2-(diphenylmethyl)-N-[(2-iodanylphenyl)methyl]-1-azabicyclo[2.2.2]octan-3-amine;ethanedioic acid;hydrate
   Show/Hide
C27H29IN2
  1
1
IC50 = 1.6 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0431661
 Compound Info 
2-Methyl-4-phenyl-quinoline-3-carboxylic acid (3,5-bis-trifluoromethyl-benzyl)-methyl-amide
   Show/Hide
C27H20F6N2O
  1
1
IC50 = 3.1 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0373477
 Compound Info 
2-Aminomethyl-4-phenyl-quinoline-3-carboxylic acid (3,5-bis-trifluoromethyl-benzyl)-methyl-amide
   Show/Hide
C27H21F6N3O
  1
1
IC50 = 9 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0465008
 Compound Info 
2-Methoxymethyl-4-phenyl-quinoline-3-carboxylic acid (3,5-bis-trifluoromethyl-benzyl)-methyl-amide
   Show/Hide
C28H22F6N2O2
  1
1
IC50 = 11 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0464802
 Compound Info 
2-Hydroxymethyl-4-phenyl-quinoline-3-carboxylic acid (3,5-bis-trifluoromethyl-benzyl)-methyl-amide
   Show/Hide
C27H20F6N2O2
  1
1
IC50 = 16 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0374972
 Compound Info 
2-(tert-Butyl-dimethyl-silanyloxymethyl)-4-phenyl-quinoline-3-carboxylic acid 3,5-bis-trifluoromethyl-benzylamide
   Show/Hide
C32H32F6N2O2Si
  1
1
IC50 = 17 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0496248
 Compound Info 
2-Chloromethyl-4-phenyl-quinoline-3-carboxylic acid 3,5-bis-trifluoromethyl-benzylamide
   Show/Hide
C26H17ClF6N2O
  1
1
IC50 = 26 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0393506
 Compound Info 
2-Bromomethyl-4-phenyl-quinoline-3-carboxylic acid (3,5-bis-trifluoromethyl-benzyl)-methyl-amide
   Show/Hide
C27H19BrF6N2O
  1
1
IC50 = 52 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0413052
 Compound Info 
2-[(Benzyl-methyl-amino)-methyl]-4-phenyl-quinoline-3-carboxylic acid 3,5-bis-trifluoromethyl-benzylamide
   Show/Hide
C34H27F6N3O
  1
1
IC50 = 180 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0392838
 Compound Info 
4-Phenyl-quinoline-3-carboxylic acid 3,5-bis-trifluoromethyl-benzylamide
   Show/Hide
C25H16F6N2O
  1
1
IC50 > 1000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0453546
 Compound Info 
2-(4-Methyl-piperazin-1-ylmethyl)-4-phenyl-quinoline-3-carboxylic acid 3,5-bis-trifluoromethyl-benzylamide
   Show/Hide
C31H28F6N4O
  1
1
IC50 > 1000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0503236
 Compound Info 
2-(1,3-Dioxo-1,3-dihydro-isoindol-2-ylmethyl)-4-phenyl-quinoline-3-carboxylic acid 3,5-bis-trifluoromethyl-benzylamide
   Show/Hide
C34H21F6N3O3
  1
1
IC50 > 1000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
Protein family and CMB statistics Related to the Cell Line
Cell Lines Derived from the same Tissue Source (Brain)
Cell Line Name Organism Disease
TS603
 Cell Line Info 
Homo sapiens (Human) Anaplastic oligodendroglioma
H4
 Cell Line Info 
Homo sapiens (Human) Astrocytoma
1321N1
 Cell Line Info 
Homo sapiens (Human) Astrocytoma
SNB-19
 Cell Line Info 
Homo sapiens (Human) Astrocytoma
U-251MG
 Cell Line Info 
Homo sapiens (Human) Astrocytoma
U-373MG ATCC
 Cell Line Info 
Homo sapiens (Human) Astrocytoma
LN-308
 Cell Line Info 
Homo sapiens (Human) Astrocytoma
CCF-STTG1
 Cell Line Info 
Homo sapiens (Human) Astrocytoma
LN-319
 Cell Line Info 
Homo sapiens (Human) Astrocytoma
P2X7-1321N1
 Cell Line Info 
Homo sapiens (Human) Astrocytoma
MDA-MB-361
 Cell Line Info 
Homo sapiens (Human) Breast adenocarcinoma
JEG-3
 Cell Line Info 
Homo sapiens (Human) Gestational choriocarcinoma
D3 [Human glioblastoma]
 Cell Line Info 
Homo sapiens (Human) Glioblastoma
LN-229
 Cell Line Info 
Homo sapiens (Human) Glioblastoma
LN-18
 Cell Line Info 
Homo sapiens (Human) Glioblastoma
A-172
 Cell Line Info 
Homo sapiens (Human) Glioblastoma
T98G
 Cell Line Info 
Homo sapiens (Human) Glioblastoma
LN229-V6R
 Cell Line Info 
Homo sapiens (Human) Glioblastoma
SF539
 Cell Line Info 
Homo sapiens (Human) Gliosarcoma
MED1
 Cell Line Info 
Homo sapiens (Human) Medulloblastoma, non-WNT/non-SHH, group 4
Kelly
 Cell Line Info 
Homo sapiens (Human) Neuroblastoma
PFSK-1
 Cell Line Info 
Homo sapiens (Human) Primitive neuroectodermal tumor
DU145
 Cell Line Info 
Homo sapiens (Human) Prostate carcinoma
DU145-TxR
 Cell Line Info 
Homo sapiens (Human) Prostate carcinoma
GL261
 Cell Line Info 
Mus musculus (Mouse) Mouse glioblastoma
C6
 Cell Line Info 
Rattus norvegicus (Rat) Rat malignant glioma
C6-BU-1
 Cell Line Info 
Rattus norvegicus (Rat) Rat malignant glioma
RG2
 Cell Line Info 
Rattus norvegicus (Rat) Rat malignant glioma
ReNcell VM
 Cell Line Info 
Homo sapiens (Human) -
hCMEC/D3
 Cell Line Info 
Homo sapiens (Human) -
BV-2
 Cell Line Info 
Mus musculus (Mouse) -
C17.2
 Cell Line Info 
Mus musculus (Mouse) -
ScGT1
 Cell Line Info 
Mus musculus (Mouse) -
bEnd.4
 Cell Line Info 
Mus musculus (Mouse) -
N39
 Cell Line Info 
Mus musculus (Mouse) -
GT1-7
 Cell Line Info 
Mus musculus (Mouse) -
N27-A
 Cell Line Info 
Rattus norvegicus (Rat) -
RBE4
 Cell Line Info 
Rattus norvegicus (Rat) -