General Information of the Compound
Compound ID
CP0413052
Compound Name
2-[(Benzyl-methyl-amino)-methyl]-4-phenyl-quinoline-3-carboxylic acid 3,5-bis-trifluoromethyl-benzylamide
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Structure
Formula
C34H27F6N3O
Molecular Weight
607.598
Canonical SMILES
CN(Cc1ccccc1)Cc1nc2ccccc2c(-c2ccccc2)c1C(=O)NCc1cc(cc(c1)C(F)(F)F)C(F)(F)F
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InChI
InChI=1S/C34H27F6N3O/c1-43(20-22-10-4-2-5-11-22)21-29-31(30(24-12-6-3-7-13-24)27-14-8-9-15-28(27)42-29)32(44)41-19-23-16-25(33(35,36)37)18-26(17-23)34(38,39)40/h2-18H,19-21H2,1H3,(H,41,44)
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InChIKey
FAMLZMYNJFMLTL-UHFFFAOYSA-N
Physicochemical Property
logP
8.5014
Rotatable Bonds
8
Heavy Atom Count
44
Polar Areas
45.23
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
3
Complexity
44

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 11192771
SID: 16273772
ChEMBL ID
CHEMBL25065
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01410, Substance-P receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000441 UC-11MG Homo sapiens (Human)  1
1
IC50 = 180 nM
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