Brief Information of the Compound and Protein
Compound Name
2-(tert-Butyl-dimethyl-silanyloxymethyl)-4-phenyl-quinoline-3-carboxylic acid 3,5-bis-trifluoromethyl-benzylamide
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PubChem ID
CID: 11433531
SID: 16530917
Canonical SMILES
CC(C)(C)[Si](C)(C)OCc1nc2ccccc2c(-c2ccccc2)c1C(=O)NCc1cc(cc(c1)C(F)(F)F)C(F)(F)F
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Compound Formula C32H32F6N2O2Si
Compound Structure
Protein Name
Substance-P receptor
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Neurokinin receptor
Uniprot ID
P25103
Gene Name
TACR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000441 UC-11MG Homo sapiens (Human)  1
1
IC50 = 17 nM
   TI
   LI
   LO
   TS