General Information of the Cell Line
Cell Line ID
CL000875
Cell Line Name
N39
Synonyms
mHypoE-N39
N39
N-39
Category
Transformed cell line
Organism
Mus musculus (Mouse)
Tissue Information
Brain
Disease None
Map of Molecular Bioactivity Related to the Cell Line
Map of Molecular Bioactivity Related to the Cell Line

Cell Line
Protein
Compound

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Cell Line
Protein ID: PT06341, Calcium/calmodulin-dependent protein kinase kinase beta
 Protein Info 
Compound ID Compound Name Compound Formula
CP0074478
 Compound Info 
4-[2-[2-methyl-5-(morpholin-4-ylmethyl)phenyl]-1H-pyrrolo[2,3-b]pyridin-4-yl]benzamide
   Show/Hide
C26H26N4O2
  1
1
IC50 = 31.62 nM
 Bioactivity Info 
   TI
   LI
   LO
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CP0117926
 Compound Info 
4-[2-[2-methyl-4-(2-morpholin-4-ylethoxy)phenyl]-1H-pyrrolo[2,3-b]pyridin-4-yl]-2-propan-2-ylbenzamide
   Show/Hide
C30H34N4O3
  1
1
IC50 = 63.1 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0329930
 Compound Info 
2-cyclopentyl-4-[2-(2-methoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-4-yl]benzamide
   Show/Hide
C26H25N3O2
  1
1
IC50 = 100 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0327761
 Compound Info 
4-[2-[3-[(dimethylamino)methyl]phenyl]-1H-pyrrolo[2,3-b]pyridin-4-yl]benzamide
   Show/Hide
C23H22N4O
  1
1
IC50 = 125.89 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0062295
 Compound Info 
4-[2-[4-[(dimethylamino)methyl]phenyl]-1H-pyrrolo[2,3-b]pyridin-4-yl]benzamide
   Show/Hide
C23H22N4O
  1
1
IC50 = 158.49 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0117918
 Compound Info 
4-[2-[2-methyl-4-(2-morpholin-4-ylethoxy)phenyl]-1H-pyrrolo[2,3-b]pyridin-4-yl]benzamide
   Show/Hide
C27H28N4O3
  1
1
IC50 = 158.49 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0074477
 Compound Info 
4-[2-[2-methyl-3-(morpholin-4-ylmethyl)phenyl]-1H-pyrrolo[2,3-b]pyridin-4-yl]benzamide
   Show/Hide
C26H26N4O2
  1
1
IC50 = 199.53 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0117924
 Compound Info 
4-[2-[2-methyl-5-(morpholin-4-ylmethyl)phenyl]-1H-pyrrolo[2,3-b]pyridin-4-yl]-2-propan-2-ylbenzamide
   Show/Hide
C29H32N4O2
  1
1
IC50 = 199.53 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0062314
 Compound Info 
4-[2-[2-methyl-3-(2-morpholin-4-ylethoxy)phenyl]-1H-pyrrolo[2,3-b]pyridin-4-yl]benzamide
   Show/Hide
C27H28N4O3
  1
1
IC50 = 251.19 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0062304
 Compound Info 
4-[2-[4-(methanesulfonamido)phenyl]-1H-pyrrolo[2,3-b]pyridin-4-yl]benzamide
   Show/Hide
C21H18N4O3S
  1
1
IC50 = 316.23 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0074480
 Compound Info 
4-[5-fluoro-2-(2-methoxyanilino)pyrimidin-4-yl]-2-propan-2-ylbenzoic acid
   Show/Hide
C21H20FN3O3
  1
1
IC50 = 398.11 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0074484
 Compound Info 
4-[2-[2-methyl-5-(morpholin-4-ylmethyl)phenyl]-1H-pyrrolo[2,3-b]pyridin-4-yl]-2-propan-2-ylbenzonitrile
   Show/Hide
C29H30N4O
  1
1
IC50 = 398.11 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0074471
 Compound Info 
4-[2-[2-methyl-4-(2-morpholin-4-ylethoxy)phenyl]-1H-pyrrolo[2,3-b]pyridin-4-yl]-2-propan-2-ylbenzonitrile
   Show/Hide
C30H32N4O2
  1
1
IC50 = 501.19 nM
 Bioactivity Info 
   TI
   LI
   LO
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CP0074476
 Compound Info 
4-[2-(3-phenylanilino)pyrimidin-4-yl]benzamide
   Show/Hide
C23H18N4O
  1
1
IC50 = 630.96 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0074481
 Compound Info 
4-[2-(2-methoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-4-yl]benzamide
   Show/Hide
C21H17N3O2
  1
1
IC50 = 794.33 nM
 Bioactivity Info 
   TI
   LI
   LO
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CP0117916
 Compound Info 
4-[2-(2-methoxyanilino)pyrimidin-4-yl]-2-propan-2-ylbenzoic acid
   Show/Hide
C21H21N3O3
  1
1
IC50 = 1000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0138857
 Compound Info 
2-cyclopentyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)benzoic acid
   Show/Hide
C25H22N2O2
  1
1
IC50 = 1258.93 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0563241
 Compound Info 
4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)-2-propan-2-ylbenzoic acid
   Show/Hide
C23H20N2O2
  1
1
IC50 = 1258.93 nM
 Bioactivity Info 
   TI
   LI
   LO
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CP0062313
 Compound Info 
4-[2-[2-methyl-4-(morpholin-4-ylmethyl)phenyl]-1H-pyrrolo[2,3-b]pyridin-4-yl]benzamide
   Show/Hide
C26H26N4O2
  1
1
IC50 = 1995.26 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0117919
 Compound Info 
4-[2-[2-methyl-5-(morpholin-4-ylmethyl)phenyl]-1H-pyrrolo[2,3-b]pyridin-4-yl]benzonitrile
   Show/Hide
C26H24N4O
  1
1
IC50 = 2511.89 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0117899
 Compound Info 
4-[2-[3-(methanesulfonamido)phenyl]-1H-pyrrolo[2,3-b]pyridin-4-yl]benzamide
   Show/Hide
C21H18N4O3S
  1
1
IC50 = 3162.28 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0218513
 Compound Info 
4-[5-fluoro-2-(2-methoxyanilino)pyrimidin-4-yl]-2-propan-2-ylbenzamide
   Show/Hide
C21H21FN4O2
  1
1
IC50 = 3162.28 nM
 Bioactivity Info 
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CP0062311
 Compound Info 
3-[4-(4-carbamoylphenyl)-1H-pyrrolo[2,3-b]pyridin-2-yl]-N-[3-(dimethylamino)propyl]benzamide
   Show/Hide
C26H27N5O2
  1
1
IC50 = 3981.07 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0074474
 Compound Info 
2-cyclopentyl-4-[5-(2-hydroxyphenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]benzamide
   Show/Hide
C25H23N3O2
  1
1
IC50 = 3981.07 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0117903
 Compound Info 
4-[2-(2-methyl-5-phenylanilino)pyrimidin-4-yl]benzamide
   Show/Hide
C24H20N4O
  1
1
IC50 = 3981.07 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0138863
 Compound Info 
2-cyclopentyl-4-(1H-pyrrolo[2,3-b]pyridin-3-yl)benzoic acid
   Show/Hide
C19H18N2O2
  1
1
IC50 = 3981.07 nM
 Bioactivity Info 
   TI
   LI
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   TS
CP0236026
 Compound Info 
4-(6-cyano-1H-pyrrolo[2,3-b]pyridin-3-yl)-2-propan-2-ylbenzoic acid
   Show/Hide
C18H15N3O2
  1
1
IC50 = 6309.57 nM
 Bioactivity Info 
   TI
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CP0538747
 Compound Info 
4-(6-cyano-1H-pyrrolo[2,3-b]pyridin-3-yl)-2-cyclopentylbenzoic acid
   Show/Hide
C20H17N3O2
  1
1
IC50 = 6309.57 nM
 Bioactivity Info 
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   LO
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CP0062291
 Compound Info 
4-[2-[2-methyl-4-(2-morpholin-4-ylethoxy)phenyl]-1H-pyrrolo[2,3-b]pyridin-4-yl]benzonitrile
   Show/Hide
C27H26N4O2
  1
1
IC50 = 7943.28 nM
 Bioactivity Info 
   TI
   LI
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CP0062297
 Compound Info 
4-[2-(2-fluoro-5-phenylanilino)pyrimidin-4-yl]benzamide
   Show/Hide
C23H17FN4O
  1
1
IC50 = 7943.28 nM
 Bioactivity Info 
   TI
   LI
   LO
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CP0074479
 Compound Info 
4-[2-(3-phenylanilino)pyrimidin-4-yl]benzoic acid
   Show/Hide
C23H17N3O2
  1
1
IC50 = 7943.28 nM
 Bioactivity Info 
   TI
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   LO
   TS
CP0062298
 Compound Info 
4-[2-(2-methoxy-5-phenylanilino)pyrimidin-4-yl]benzamide
   Show/Hide
C24H20N4O2
  1
1
IC50 > 10000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0062299
 Compound Info 
4-[2-(2-methoxyanilino)pyrimidin-4-yl]benzamide
   Show/Hide
C18H16N4O2
  1
1
IC50 > 10000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0074473
 Compound Info 
2-cyclopentyl-4-[5-(2-propan-2-yloxyphenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]benzamide
   Show/Hide
C28H29N3O2
  1
1
IC50 > 10000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0074475
 Compound Info 
4-[5-chloro-2-(2-methoxyanilino)pyrimidin-4-yl]-2-propan-2-ylbenzamide
   Show/Hide
C21H21ClN4O2
  1
1
IC50 > 10000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0117915
 Compound Info 
4-[2-(2-methoxyanilino)pyrimidin-4-yl]benzoic acid
   Show/Hide
C18H15N3O3
  1
1
IC50 > 10000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0117921
 Compound Info 
4-[2-(2-methoxyanilino)pyrimidin-4-yl]-2-propan-2-ylbenzamide
   Show/Hide
C21H22N4O2
  1
1
IC50 > 10000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0218511
 Compound Info 
2-cyclopentyl-4-[5-[2-(dimethylamino)phenyl]-1H-pyrrolo[2,3-b]pyridin-3-yl]benzamide
   Show/Hide
C27H28N4O
  1
1
IC50 > 10000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0218512
 Compound Info 
2-cyclopentyl-4-[5-(2-phenoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]benzamide
   Show/Hide
C31H27N3O2
  1
1
IC50 > 10000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0327760
 Compound Info 
4-[2-[4-[3-(dimethylamino)propylcarbamoyl]phenyl]-1H-pyrrolo[2,3-b]pyridin-4-yl]benzamide
   Show/Hide
C26H27N5O2
  1
1
IC50 > 10000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0329929
 Compound Info 
2-cyclopentyl-4-(6-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl)benzoic acid
   Show/Hide
C20H20N2O2
  1
1
IC50 > 10000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0475074
 Compound Info 
2-cyclopentyl-4-[5-(2-methoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]benzamide
   Show/Hide
C26H25N3O2
  1
1
IC50 > 10000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0561295
 Compound Info 
2-cyclopentyl-4-[5-[2-(trifluoromethoxy)phenyl]-1H-pyrrolo[2,3-b]pyridin-3-yl]benzamide
   Show/Hide
C26H22F3N3O2
  1
1
IC50 > 10000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
Protein family and CMB statistics Related to the Cell Line
Cell Lines Derived from the same Tissue Source (Brain)
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TS603
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 Cell Line Info 
Homo sapiens (Human) Astrocytoma
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 Cell Line Info 
Homo sapiens (Human) Astrocytoma
U-373MG ATCC
 Cell Line Info 
Homo sapiens (Human) Astrocytoma
LN-308
 Cell Line Info 
Homo sapiens (Human) Astrocytoma
CCF-STTG1
 Cell Line Info 
Homo sapiens (Human) Astrocytoma
LN-319
 Cell Line Info 
Homo sapiens (Human) Astrocytoma
P2X7-1321N1
 Cell Line Info 
Homo sapiens (Human) Astrocytoma
MDA-MB-361
 Cell Line Info 
Homo sapiens (Human) Breast adenocarcinoma
JEG-3
 Cell Line Info 
Homo sapiens (Human) Gestational choriocarcinoma
D3 [Human glioblastoma]
 Cell Line Info 
Homo sapiens (Human) Glioblastoma
LN-229
 Cell Line Info 
Homo sapiens (Human) Glioblastoma
LN-18
 Cell Line Info 
Homo sapiens (Human) Glioblastoma
A-172
 Cell Line Info 
Homo sapiens (Human) Glioblastoma
UC-11MG
 Cell Line Info 
Homo sapiens (Human) Glioblastoma
T98G
 Cell Line Info 
Homo sapiens (Human) Glioblastoma
LN229-V6R
 Cell Line Info 
Homo sapiens (Human) Glioblastoma
SF539
 Cell Line Info 
Homo sapiens (Human) Gliosarcoma
MED1
 Cell Line Info 
Homo sapiens (Human) Medulloblastoma, non-WNT/non-SHH, group 4
Kelly
 Cell Line Info 
Homo sapiens (Human) Neuroblastoma
PFSK-1
 Cell Line Info 
Homo sapiens (Human) Primitive neuroectodermal tumor
DU145
 Cell Line Info 
Homo sapiens (Human) Prostate carcinoma
DU145-TxR
 Cell Line Info 
Homo sapiens (Human) Prostate carcinoma
GL261
 Cell Line Info 
Mus musculus (Mouse) Mouse glioblastoma
C6
 Cell Line Info 
Rattus norvegicus (Rat) Rat malignant glioma
C6-BU-1
 Cell Line Info 
Rattus norvegicus (Rat) Rat malignant glioma
RG2
 Cell Line Info 
Rattus norvegicus (Rat) Rat malignant glioma
ReNcell VM
 Cell Line Info 
Homo sapiens (Human) -
hCMEC/D3
 Cell Line Info 
Homo sapiens (Human) -
BV-2
 Cell Line Info 
Mus musculus (Mouse) -
C17.2
 Cell Line Info 
Mus musculus (Mouse) -
ScGT1
 Cell Line Info 
Mus musculus (Mouse) -
bEnd.4
 Cell Line Info 
Mus musculus (Mouse) -
GT1-7
 Cell Line Info 
Mus musculus (Mouse) -
N27-A
 Cell Line Info 
Rattus norvegicus (Rat) -
RBE4
 Cell Line Info 
Rattus norvegicus (Rat) -