Brief Information of the Compound and Protein
Compound Name
tert-butyl 4-[[3,5-bis(trifluoromethyl)phenyl]methoxymethyl]-4-phenylpiperidine-1-carboxylate
    Show/Hide
PubChem ID
CID: 10369316
SID: 15382850
Canonical SMILES
CC(C)(C)OC(=O)N1CCC(COCc2cc(cc(c2)C(F)(F)F)C(F)(F)F)(CC1)c1ccccc1
    Show/Hide
Compound Formula C26H29F6NO3
Compound Structure
Protein Name
Substance-P receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
>
Short peptide receptor (family A GPCR)
>
Neurokinin receptor
Uniprot ID
P25103
Gene Name
TACR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000205 U-373MG ATCC Homo sapiens (Human)  1
1
IC50 = 170 nM
   TI
   LI
   LO
   TS