Brief Information of the Compound and Protein
Compound Name
(4S)-1-benzyl-4-[[3,5-bis(trifluoromethyl)phenyl]methoxymethyl]-4-phenylazepane
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PubChem ID
CID: 11634999
SID: 16738141
Canonical SMILES
FC(F)(F)c1cc(COC[C@]2(CCCN(Cc3ccccc3)CC2)c2ccccc2)cc(c1)C(F)(F)F
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Compound Formula C29H29F6NO
Compound Structure
Protein Name
Substance-P receptor
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Neurokinin receptor
Uniprot ID
P25103
Gene Name
TACR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000205 U-373MG ATCC Homo sapiens (Human)  1
1
IC50 = 74 nM
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   LI
   LO
   TS