Brief Information of the Compound and Protein
Compound Name
(3R)-3-[[3,5-bis(trifluoromethyl)phenyl]methoxymethyl]-1-methyl-3-phenylazepane
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PubChem ID
CID: 71583203
SID: 163635141
Canonical SMILES
CN1CCCC[C@](COCc2cc(cc(c2)C(F)(F)F)C(F)(F)F)(C1)c1ccccc1
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Compound Formula C23H25F6NO
Compound Structure
Protein Name
Substance-P receptor
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Neurokinin receptor
Uniprot ID
P25103
Gene Name
TACR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000205 U-373MG ATCC Homo sapiens (Human)  1
1
IC50 = 660 nM
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   LI
   LO
   TS