Brief Information of the Compound and Protein
Compound Name
 Compound Info 
benzyl N-[(2R)-1-[(2S)-2-cyanopyrrolidin-1-yl]-1-oxopropan-2-yl]carbamate
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 PubChem ID
CID: 44541222
SID: 87222761
Canonical SMILES
C[C@@H](NC(=O)OCc1ccccc1)C(=O)N1CCC[C@H]1C#N
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Compound Formula C16H19N3O3
Compound Structure
Protein Name
 Protein Info 
Prolyl endopeptidase
Protein Classification
Enzyme
>
Protease
>
Serine protease
>
Serine protease SC clan
>
Serine protease S9A subfamily
Uniprot ID
P48147
Gene Name
PREP
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000419 HCE-T
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 6600 nM
   TI
   LI
   LO
   TS
CL000417 LN-229
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 7500 nM
   TI
   LI
   LO
   TS
CL000418 LN-308
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 4700 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 1200 nM
2 IC50 = 1400 nM