General Information of the Cell Line
Cell Line ID
CL000419
Cell Line Name
HCE-T
Synonyms
HCET
Human Corneal Epithelial cells-Transformed
HCE
SV40-HCEC
Category
Transformed cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_1272
Tissue Information
Eye
Disease None
Map of Molecular Bioactivity Related to the Cell Line
Map of Molecular Bioactivity Related to the Cell Line

Cell Line
Protein
Compound

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Cell Line
Protein ID: PT01037, Prolyl endopeptidase
Compound ID Compound Name Compound Formula
CP0044004
benzyl N-[(2S)-1-[(2S)-2-cyanopyrrolidin-1-yl]-1-oxopropan-2-yl]carbamate
   Show/Hide
C16H19N3O3
 1
1
IC50 = 20 nM
   TI
   LI
   LO
   TS
CP0075193
benzyl N-[2-[(2S)-2-cyanopyrrolidin-1-yl]-2-oxoethyl]carbamate
   Show/Hide
C15H17N3O3
 1
1
IC50 = 180 nM
   TI
   LI
   LO
   TS
CP0043934
(2R,5S,7R)-1-Aza-7-benzyloxycarbonylamino-8-oxo-4-thiabicyclo[3.3.0]octane-2-carbonitrile
   Show/Hide
C15H15N3O3S
 1
1
IC50 = 1300 nM
   TI
   LI
   LO
   TS
CP0166361
benzyl N-[2-[(2R)-2-cyanopyrrolidin-1-yl]-2-oxoethyl]carbamate
   Show/Hide
C15H17N3O3
 1
1
IC50 = 2800 nM
   TI
   LI
   LO
   TS
CP0181871
benzyl N-[(2R)-1-[(2S)-2-cyanopyrrolidin-1-yl]-1-oxopropan-2-yl]carbamate
   Show/Hide
C16H19N3O3
 1
1
IC50 = 6600 nM
   TI
   LI
   LO
   TS
Cell Viability or Cytotoxicity Assay
Compound ID Compound Name Compound Formula
CP0281764
(R)-2-(((2R,3R,4R)-3,4-dihydroxy-1-methyl-5-oxopyrrolidin-2-yl)methylamino)-2-phenylethyl 4-bromobenzoate
   Show/Hide
C21H23BrN2O5  1
1
IC50 = 100000 nM
   TI
   LI
   LO
   TS
Protein family and CMB statistics Related to the Cell Line
Cell Lines Derived from the same Tissue Source (Eye)
Cell Line Name Organism Disease
CHRF Homo sapiens (Human) Childhood acute megakaryoblastic leukemia
GTM-3 Homo sapiens (Human) Glaucoma
Y-79 Homo sapiens (Human) Retinoblastoma
MIO-M1 Homo sapiens (Human) -
RGC-5 Mus musculus (Mouse) -
661W Mus musculus (Mouse) -
FG-9307 Paralichthys olivaceus (Bastard halibut) -