Brief Information of the Compound and Protein
Compound Name
 Compound Info 
US9096596, 83
    Show/Hide
 PubChem ID
CID: 86280736
Canonical SMILES
Cc1nc2c(c(-c3ccn[nH]3)n1)CC(C)N(C(=O)c1ccc(Cl)cc1Cl)C2
    Show/Hide
Compound Formula C19H17Cl2N5O
Compound Structure
Protein Name
 Protein Info 
P2X purinoceptor 7
Protein Classification
Ion channel
>
Ligand-gated ion channel
>
P2X receptor
Uniprot ID
Q99572
Gene Name
P2RX7
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000094 1321N1
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 1.7 nM
   TI
   LI
   LO
   TS
CL000881 P2X7-1321N1
 Cell Line Info 
Homo sapiens (Human)  1
1
Ki = 31.6 nM
   TI
   LI
   LO
   TS