General Information of the Compound
Compound ID
CP0862900
Compound Name
(6aS,9aS)-6a-Methyl-2,3,5,6,6a,8,9,9a,10,11-decahydro-1H-indeno[5,4-f]quinoline-4,7-dione; compound with (6aS,9aS)-6a-methyl-2,3,6,6a,8,9,9a,9b,10,11-decahydro-1H-indeno[5,4-f]quinoline-4,7-dione
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Structure
Formula
C34H42N2O4
Molecular Weight
542.72
Canonical SMILES
C[C@]12CC=C3C4=C(CCC3[C@@H]1CCC2=O)NCCC4=O.C[C@]12CCC3=C(CCC4=C3C(=O)CCN4)[C@@H]1CCC2=O
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InChI
InChI=1S/2C17H21NO2/c2*1-17-8-6-11-10(12(17)3-5-15(17)20)2-4-13-16(11)14(19)7-9-18-13/h12,18H,2-9H2,1H3;6,10,12,18H,2-5,7-9H2,1H3/t12-,17-;10?,12-,17-/m00/s1
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InChIKey
DJEYGWAYDUMQDJ-ZYYYDXMESA-N
Physicochemical Property
logP
5.2009
Rotatable Bonds
0
Heavy Atom Count
40
Polar Areas
92.34
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
6
Complexity
40

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 52947849
ChEMBL ID
CHEMBL1237307
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01430, 3-oxo-5-alpha-steroid 4-dehydrogenase 1
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000119 DU145 Homo sapiens (Human)  1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS