| Compound ID |
Compound Name |
Compound Formula |
|
CP0386998
|
(1S,2S,6R,14R,15R,16R)-16-[(1S)-2-cyclohexyl-1-hydroxyethyl]-5-(cyclopropylmethyl)-15-methoxy-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-trien-11-ol
Show/Hide
|
C31H43NO4
|
2
|
| 1 |
EC50 = 0.094 nM
|
|
|
| 2 |
Ki = 0.27 nM
|
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|
|
CP0428801
|
(1S,2S,6R,14R,15R,16R)-16-[(S)-cyclohexyl(hydroxy)methyl]-5-(cyclopropylmethyl)-15-methoxy-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-trien-11-ol
Show/Hide
|
C30H41NO4
|
2
|
| 1 |
EC50 = 0.12 nM
|
|
|
| 2 |
Ki = 0.41 nM
|
|
|
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CP0430970
|
(2S)-2-amino-N-[(4R)-6-(3,4-dihydro-1H-isoquinolin-2-ylmethyl)-1-methylsulfonyl-3,4-dihydro-2H-quinolin-4-yl]-3-(4-hydroxy-2,6-dimethylphenyl)propanamide;2,2,2-trifluoroacetic acid
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|
C33H39F3N4O6S
|
2
|
| 1 |
EC50 = 0.12 nM
|
|
|
| 2 |
Ki = 0.11 nM
|
|
|
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CP0385288
|
(1S,2S,6R,14R,15R,16R)-5-(cyclopropylmethyl)-16-[(1S)-1-hydroxy-4-methylpentyl]-15-methoxy-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-trien-11-ol
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|
C29H41NO4
|
2
|
| 1 |
EC50 = 0.16 nM
|
|
|
| 2 |
Ki = 0.12 nM
|
|
|
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CP0386999
|
(1S,2S,6R,14R,15R,16R)-16-[(1S)-3-cyclopentyl-1-hydroxypropyl]-5-(cyclopropylmethyl)-15-methoxy-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-trien-11-ol
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|
C31H43NO4
|
2
|
| 1 |
EC50 = 0.16 nM
|
|
|
| 2 |
Ki = 0.49 nM
|
|
|
|
CP0417740
|
(1S,2S,6R,14R,15R,16R)-16-[(1S)-2-cyclopentyl-1-hydroxyethyl]-5-(cyclopropylmethyl)-15-methoxy-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-trien-11-ol
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|
C30H41NO4
|
2
|
| 1 |
EC50 = 0.16 nM
|
|
|
| 2 |
Ki = 0.36 nM
|
|
|
|
CP0429480
|
(2E)-N-[(1S,5R,13R,14R,17S)-4-(cyclopropylmethyl)-10,17-dihydroxy-12-oxa-4-azapentacyclo[9.6.1.0^{1,13}.0^{5,17}.0^{7,18}]octadeca-7(18),8,10-trien-14-yl]-3-(3-nitrophenyl)prop-2-enamide
Show/Hide
|
C29H31N3O6
|
2
|
| 1 |
EC50 = 0.18 nM
|
|
|
| 2 |
Ki = 0.11 nM
|
|
|
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CP0385766
|
(1S,2S,6R,14R,15R,16R)-5-(cyclopropylmethyl)-16-[(2R)-2-hydroxy-5-methylhexan-2-yl]-15-methoxy-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-trien-11-ol
Show/Hide
|
C30H43NO4
|
2
|
| 1 |
EC50 = 0.19 nM
|
|
|
| 2 |
Ki = 0.22 nM
|
|
|
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CP0391786
|
(1S,2S,6R,14R,15R,16R)-16-[(1S)-3-cyclohexyl-1-hydroxypropyl]-5-(cyclopropylmethyl)-15-methoxy-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-trien-11-ol
Show/Hide
|
C32H45NO4
|
2
|
| 1 |
EC50 = 0.2 nM
|
|
|
| 2 |
Ki = 0.23 nM
|
|
|
|
CP0380831
|
(1R,2S,6R,14R,15R,19R)-5-(cyclopropylmethyl)-19-[(R)-(4-fluorophenyl)-hydroxymethyl]-15-methoxy-19-methyl-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11,16-tetraen-11-ol
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|
C31H34FNO4
|
2
|
| 1 |
EC50 = 0.22 nM
|
|
|
| 2 |
Ki = 0.16 nM
|
|
|
|
CP0426864
|
(1S,2S,6R,14R,15R,16R)-5-(cyclopropylmethyl)-16-[(1S)-1-hydroxy-2-phenylethyl]-15-methoxy-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-trien-11-ol
Show/Hide
|
C31H37NO4
|
2
|
| 1 |
EC50 = 0.23 nM
|
|
|
| 2 |
Ki = 0.03 nM
|
|
|
|
CP0468797
|
(2S)-2-amino-N-[(4R)-6-benzyl-1-methylsulfonyl-3,4-dihydro-2H-quinolin-4-yl]-3-(4-hydroxy-2,6-dimethylphenyl)propanamide;2,2,2-trifluoroacetic acid
Show/Hide
|
C30H34F3N3O6S
|
2
|
| 1 |
EC50 = 0.23 nM
|
|
|
| 2 |
Ki = 0.06 nM
|
|
|
|
CP0475259
|
(2S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)-N-[(4R)-1-methylsulfonyl-6-(naphthalen-2-ylmethyl)-3,4-dihydro-2H-quinolin-4-yl]propanamide;2,2,2-trifluoroacetic acid
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|
C34H36F3N3O6S
|
2
|
| 1 |
EC50 = 0.23 nM
|
|
|
| 2 |
Ki = 0.04 nM
|
|
|
|
CP0385221
|
(2S)-2-amino-N-[(4R)-6-(2,3-dihydro-1H-inden-2-ylmethyl)-1,2,3,4-tetrahydroquinolin-4-yl]-3-(4-hydroxy-2,6-dimethylphenyl)propanamide
Show/Hide
|
C30H35N3O2
|
2
|
| 1 |
EC50 = 0.24 nM
|
|
|
| 2 |
Ki = 0.16 nM
|
|
|
|
CP0385501
|
(1R,2S,6R,14R,15R,19R)-5-(cyclopropylmethyl)-19-[(R)-hydroxy-(4-methylphenyl)methyl]-15-methoxy-19-methyl-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11,16-tetraen-11-ol
Show/Hide
|
C32H37NO4
|
1
|
| 1 |
EC50 = 0.24 nM
|
|
|
|
CP0387000
|
(1S,2S,6R,14R,15R,16R)-16-[(R)-cyclohexyl(hydroxy)methyl]-5-(cyclopropylmethyl)-15-methoxy-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-trien-11-ol
Show/Hide
|
C30H41NO4
|
2
|
| 1 |
EC50 = 0.26 nM
|
|
|
| 2 |
Ki = 0.15 nM
|
|
|
|
CP0451771
|
(2S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)-N-[(4R)-1-methylsulfonyl-6-(quinolin-3-ylmethyl)-3,4-dihydro-2H-quinolin-4-yl]propanamide;2,2,2-trifluoroacetic acid
Show/Hide
|
C33H35F3N4O6S
|
2
|
| 1 |
EC50 = 0.26 nM
|
|
|
| 2 |
Ki = 0.23 nM
|
|
|
|
CP0072627
|
BUPRENORPHINE
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|
C29H41NO4
|
4
|
| 1 |
EC50 = 0.27 nM
|
|
|
| 2 |
EC50 = 0.7 nM
|
|
|
| 3 |
Ki = 0.13 nM
|
|
|
| 4 |
Ki = 0.19 nM
|
|
|
|
CP0387002
|
(1S,2S,6R,14R,15R,16R)-16-[(S)-cyclopentyl(hydroxy)methyl]-5-(cyclopropylmethyl)-15-methoxy-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-trien-11-ol
Show/Hide
|
C29H39NO4
|
2
|
| 1 |
EC50 = 0.29 nM
|
|
|
| 2 |
Ki = 1 nM
|
|
|
|
CP0385284
|
(1S,2S,6R,14R,15R,16R)-5-(cyclopropylmethyl)-16-[(1R)-1-hydroxy-2-phenylethyl]-15-methoxy-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-trien-11-ol
Show/Hide
|
C31H37NO4
|
2
|
| 1 |
EC50 = 0.32 nM
|
|
|
| 2 |
Ki = 0.038 nM
|
|
|
|
CP0447074
|
(2S)-2-amino-N-[(4R)-1-(cyclopropanecarbonyl)-6-(quinolin-3-ylmethyl)-3,4-dihydro-2H-quinolin-4-yl]-3-(4-hydroxy-2,6-dimethylphenyl)propanamide;2,2,2-trifluoroacetic acid
Show/Hide
|
C36H37F3N4O5
|
2
|
| 1 |
EC50 = 0.34 nM
|
|
|
| 2 |
Ki = 0.05 nM
|
|
|
|
CP0489973
|
(2S)-2-amino-N-[(4R)-6-(1-benzofuran-2-ylmethyl)-1-methylsulfonyl-3,4-dihydro-2H-quinolin-4-yl]-3-(4-hydroxy-2,6-dimethylphenyl)propanamide;2,2,2-trifluoroacetic acid
Show/Hide
|
C32H34F3N3O7S
|
2
|
| 1 |
EC50 = 0.34 nM
|
|
|
| 2 |
Ki = 0.05 nM
|
|
|
|
CP0429384
|
methyl (4R)-4-[[(2S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanoyl]amino]-6-(naphthalen-2-ylmethyl)-3,4-dihydro-2H-quinoline-1-carboxylate
Show/Hide
|
C33H35N3O4
|
2
|
| 1 |
EC50 = 0.39 nM
|
|
|
| 2 |
Ki = 0.32 nM
|
|
|
|
CP0451768
|
(2S)-2-amino-N-[(4R)-6-(3,4-dihydro-1H-isoquinolin-2-ylmethyl)-1,2,3,4-tetrahydroquinolin-4-yl]-3-(4-hydroxy-2,6-dimethylphenyl)propanamide;2,2,2-trifluoroacetic acid
Show/Hide
|
C32H37F3N4O4
|
2
|
| 1 |
EC50 = 0.4 nM
|
|
|
| 2 |
Ki = 0.03 nM
|
|
|
|
CP0452046
|
(2S)-2-amino-N-[(4R)-1-(cyclopropanecarbonyl)-6-(naphthalen-2-ylmethyl)-3,4-dihydro-2H-quinolin-4-yl]-3-(4-hydroxy-2,6-dimethylphenyl)propanamide;2,2,2-trifluoroacetic acid
Show/Hide
|
C37H38F3N3O5
|
2
|
| 1 |
EC50 = 0.42 nM
|
|
|
| 2 |
Ki = 0.05 nM
|
|
|
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CP0385294
|
(1S,2S,6R,14R,15R,16R)-16-[(1R)-1-cyclohexyl-1-hydroxyethyl]-5-(cyclopropylmethyl)-15-methoxy-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-trien-11-ol
Show/Hide
|
C31H43NO4
|
2
|
| 1 |
EC50 = 0.43 nM
|
|
|
| 2 |
Ki = 0.21 nM
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|
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CP0428800
|
(1S,2S,6R,14R,15R,16R)-5-(cyclopropylmethyl)-16-[(2S)-2-hydroxy-5-methylhexan-2-yl]-15-methoxy-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-trien-11-ol
Show/Hide
|
C30H43NO4
|
2
|
| 1 |
EC50 = 0.43 nM
|
|
|
| 2 |
Ki = 0.21 nM
|
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CP0391804
|
(1S,2S,6R,14R,15R,16R)-5-(cyclopropylmethyl)-16-[(1S)-1-hydroxy-3-methylbutyl]-15-methoxy-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-trien-11-ol
Show/Hide
|
C28H39NO4
|
2
|
| 1 |
EC50 = 0.48 nM
|
|
|
| 2 |
Ki = 0.68 nM
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CP0385133
|
(2S)-N-[(4R)-1-acetyl-6-(naphthalen-1-ylmethyl)-3,4-dihydro-2H-quinolin-4-yl]-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanamide
Show/Hide
|
C33H35N3O3
|
2
|
| 1 |
EC50 = 0.48 nM
|
|
|
| 2 |
Ki = 0.06 nM
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CP0430965
|
(2S)-2-amino-N-[(4R)-1-(cyclopropanecarbonyl)-6-(3,4-dihydro-1H-isoquinolin-2-ylmethyl)-3,4-dihydro-2H-quinolin-4-yl]-3-(4-hydroxy-2,6-dimethylphenyl)propanamide;2,2,2-trifluoroacetic acid
Show/Hide
|
C36H41F3N4O5
|
2
|
| 1 |
EC50 = 0.52 nM
|
|
|
| 2 |
Ki = 0.12 nM
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|
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CP0385121
|
(2S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)-N-[(4R)-6-(naphthalen-2-ylmethyl)-1,2,3,4-tetrahydroquinolin-4-yl]propanamide
Show/Hide
|
C31H33N3O2
|
2
|
| 1 |
EC50 = 0.53 nM
|
|
|
| 2 |
Ki = 0.078 nM
|
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CP0385285
|
(1S,2S,6R,14R,15R,16R)-16-[(1R)-2-cyclohexyl-1-hydroxyethyl]-5-(cyclopropylmethyl)-15-methoxy-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-trien-11-ol
Show/Hide
|
C31H43NO4
|
2
|
| 1 |
EC50 = 0.56 nM
|
|
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| 2 |
Ki = 0.043 nM
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CP0391803
|
(1S,2S,6R,14R,15R,16R)-16-[(2R)-1-cyclopentyl-2-hydroxypropan-2-yl]-5-(cyclopropylmethyl)-15-methoxy-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-trien-11-ol
Show/Hide
|
C31H43NO4
|
2
|
| 1 |
EC50 = 0.56 nM
|
|
|
| 2 |
Ki = 0.29 nM
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CP0382583
|
(2S)-N-[(4R)-1-acetyl-6-(2,3-dihydro-1H-inden-2-ylmethyl)-3,4-dihydro-2H-quinolin-4-yl]-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanamide
Show/Hide
|
C32H37N3O3
|
2
|
| 1 |
EC50 = 0.56 nM
|
|
|
| 2 |
Ki = 0.05 nM
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CP0474697
|
14beta-Allyloxy-17-cyclopropylmethyl-4,5alpha-epoxy-3-hydroxy-6beta-(cinnamoylamino)morphinan
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|
C32H36N2O4
|
2
|
| 1 |
EC50 = 0.6 nM
|
|
|
| 2 |
Ki = 0.25 nM
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CP0386997
|
(1S,2S,6R,14R,15R,16R)-16-[(R)-cyclopentyl(hydroxy)methyl]-5-(cyclopropylmethyl)-15-methoxy-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-trien-11-ol
Show/Hide
|
C29H39NO4
|
2
|
| 1 |
EC50 = 0.6 nM
|
|
|
| 2 |
Ki = 0.31 nM
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CP0385113
|
(2S)-N-[(4R)-1-acetyl-6-(cyclohexylmethyl)-3,4-dihydro-2H-quinolin-4-yl]-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanamide
Show/Hide
|
C29H39N3O3
|
2
|
| 1 |
EC50 = 0.61 nM
|
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| 2 |
Ki = 0.03 nM
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CP0428156
|
(2E)-N-[(1S,5R,13R,14R,17S)-4-(cyclopropylmethyl)-10,17-dihydroxy-12-oxa-4-azapentacyclo[9.6.1.0^{1,13}.0^{5,17}.0^{7,18}]octadeca-7(18),8,10-trien-14-yl]-3-(2-nitrophenyl)prop-2-enamide
Show/Hide
|
C29H31N3O6
|
2
|
| 1 |
EC50 = 0.69 nM
|
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| 2 |
Ki = 0.35 nM
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CP0418848
|
(1S,2S,6R,14R,15R,16R)-16-[(2S)-1-cyclohexyl-2-hydroxypropan-2-yl]-5-(cyclopropylmethyl)-15-methoxy-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-trien-11-ol
Show/Hide
|
C32H45NO4
|
2
|
| 1 |
EC50 = 0.72 nM
|
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| 2 |
Ki = 0.37 nM
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CP0409019
|
(1R,5R,9S)-5-(3-hydroxyphenyl)-2-[2-(4-nitrophenyl)ethyl]-2-azabicyclo[3.3.1]nonan-9-ol;oxalic acid
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|
C24H28N2O8
|
1
|
| 1 |
EC50 = 0.74 nM
|
|
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CP0420051
|
methyl (4R)-4-[[(2S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanoyl]amino]-6-benzyl-3,4-dihydro-2H-quinoline-1-carboxylate
Show/Hide
|
C29H33N3O4
|
2
|
| 1 |
EC50 = 0.78 nM
|
|
|
| 2 |
Ki = 0.19 nM
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CP0385126
|
(2S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)-N-[(4R)-6-(naphthalen-1-ylmethyl)-1,2,3,4-tetrahydroquinolin-4-yl]propanamide
Show/Hide
|
C31H33N3O2
|
2
|
| 1 |
EC50 = 0.84 nM
|
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| 2 |
Ki = 0.76 nM
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CP0391773
|
(1S,2S,6R,14R,15R,16R)-5-(cyclopropylmethyl)-16-[(2S)-2-hydroxy-4-methylpentan-2-yl]-15-methoxy-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-trien-11-ol
Show/Hide
|
C29H41NO4
|
2
|
| 1 |
EC50 = 0.85 nM
|
|
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| 2 |
Ki = 0.19 nM
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CP0420052
|
(2S)-2-amino-N-[(4R)-1-butanoyl-6-(naphthalen-2-ylmethyl)-3,4-dihydro-2H-quinolin-4-yl]-3-(4-hydroxy-2,6-dimethylphenyl)propanamide
Show/Hide
|
C35H39N3O3
|
2
|
| 1 |
EC50 = 0.9 nM
|
|
|
| 2 |
Ki = 0.14 nM
|
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|
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CP0447077
|
(2S)-2-amino-N-[(4R)-6-(1-benzofuran-2-ylmethyl)-1-(cyclopropanecarbonyl)-3,4-dihydro-2H-quinolin-4-yl]-3-(4-hydroxy-2,6-dimethylphenyl)propanamide;2,2,2-trifluoroacetic acid
Show/Hide
|
C35H36F3N3O6
|
2
|
| 1 |
EC50 = 0.9 nM
|
|
|
| 2 |
Ki = 0.05 nM
|
|
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CP0385129
|
(2S)-N-[(4R)-1-acetyl-6-(naphthalen-2-ylmethyl)-3,4-dihydro-2H-quinolin-4-yl]-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanamide
Show/Hide
|
C33H35N3O3
|
2
|
| 1 |
EC50 = 0.93 nM
|
|
|
| 2 |
Ki = 0.04 nM
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|
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CP0468323
|
14beta-Acetoyloxy-17-cyclopropylmethyl-4,5alpha-epoxy-3-hydroxy-6beta-(cinnamoylamino)morphinan
Show/Hide
|
C31H34N2O5
|
2
|
| 1 |
EC50 = 1 nM
|
|
|
| 2 |
Ki = 0.21 nM
|
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|
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CP0385289
|
(1S,2S,6R,14R,15R,16R)-5-(cyclopropylmethyl)-16-[(1R)-1-hydroxy-2-methylpropyl]-15-methoxy-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-trien-11-ol
Show/Hide
|
C27H37NO4
|
2
|
| 1 |
EC50 = 1 nM
|
|
|
| 2 |
Ki = 0.33 nM
|
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CP0385290
|
(1S,2S,6R,14R,15R,16R)-16-[(1S)-1-cyclopentyl-1-hydroxyethyl]-5-(cyclopropylmethyl)-15-methoxy-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-trien-11-ol
Show/Hide
|
C30H41NO4
|
2
|
| 1 |
EC50 = 1 nM
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|
|
| 2 |
Ki = 0.18 nM
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CP0391807
|
(1R,2S,6R,14R,15R,19R)-5-(cyclopropylmethyl)-19-[(2R)-2-hydroxy-5-methylhexan-2-yl]-15-methoxy-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11,16-tetraen-11-ol
Show/Hide
|
C30H41NO4
|
2
|
| 1 |
EC50 = 1 nM
|
|
|
| 2 |
Ki = 0.18 nM
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|
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|
CP0430968
|
(2S)-2-amino-N-[(4R)-1-benzoyl-6-(quinolin-3-ylmethyl)-3,4-dihydro-2H-quinolin-4-yl]-3-(4-hydroxy-2,6-dimethylphenyl)propanamide;2,2,2-trifluoroacetic acid
Show/Hide
|
C39H37F3N4O5
|
2
|
| 1 |
EC50 = 1 nM
|
|
|
| 2 |
Ki = 0.04 nM
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|
|
|
CP0410855
|
(2S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)-N-[(4R)-6-(2-phenylethyl)-1,2,3,4-tetrahydroquinolin-4-yl]propanamide
Show/Hide
|
C28H33N3O2
|
2
|
| 1 |
EC50 = 1.1 nM
|
|
|
| 2 |
Ki = 0.24 nM
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|
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|
CP0451766
|
(2S)-2-amino-N-[(4R)-6-(1-benzofuran-2-ylmethyl)-1,2,3,4-tetrahydroquinolin-4-yl]-3-(4-hydroxy-2,6-dimethylphenyl)propanamide;2,2,2-trifluoroacetic acid
Show/Hide
|
C31H32F3N3O5
|
2
|
| 1 |
EC50 = 1.1 nM
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|
|
| 2 |
Ki = 0.11 nM
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|
CP0451769
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(2S)-N-[(4R)-1-acetyl-6-(quinolin-3-ylmethyl)-3,4-dihydro-2H-quinolin-4-yl]-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanamide;2,2,2-trifluoroacetic acid
Show/Hide
|
C34H35F3N4O5
|
2
|
| 1 |
EC50 = 1.1 nM
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|
|
| 2 |
Ki = 0.15 nM
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|
CP0458891
|
(5R,8S,11S,14S)-14-((S)-2-amino-3-(4-hydroxyphenyl)propanamido)-11-benzyl-8-(naphthalen-2-ylmethyl)-7,10,13-trioxo-1,3-dithia-6,9,12-triazacyclopentadecane-5-carboxamide
Show/Hide
|
C38H42N6O6S2
|
2
|
| 1 |
EC50 = 1.2 nM
|
|
|
| 2 |
Ki = 0.47 nM
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|
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|
CP0391806
|
(1S,2S,6R,14R,15R,16R)-5-(cyclopropylmethyl)-16-[(2R)-2-hydroxy-4-methylpentan-2-yl]-15-methoxy-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-trien-11-ol
Show/Hide
|
C29H41NO4
|
2
|
| 1 |
EC50 = 1.2 nM
|
|
|
| 2 |
Ki = 0.2 nM
|
|
|
|
CP0385291
|
(1S,2S,6R,14R,15R,16R)-5-(cyclopropylmethyl)-16-[(2S)-2-hydroxy-3-methylbutan-2-yl]-15-methoxy-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-trien-11-ol
Show/Hide
|
C28H39NO4
|
2
|
| 1 |
EC50 = 1.27 nM
|
|
|
| 2 |
Ki = 0.091 nM
|
|
|
|
CP0423635
|
(1S,5R,13R,14R,17S)-4-(cyclopropylmethyl)-10-hydroxy-14-[(2E)-3-phenylprop-2-enamido]-12-oxa-4-azapentacyclo[9.6.1.0^{1,13}.0^{5,17}.0^{7,18}]octadeca-7(18),8,10-trien-17-yl 2-phenylacetate
Show/Hide
|
C37H38N2O5
|
2
|
| 1 |
EC50 = 1.3 nM
|
|
|
| 2 |
Ki = 0.28 nM
|
|
|
|
CP0385292
|
(1S,2S,6R,14R,15R,16R)-5-(cyclopropylmethyl)-16-[(2R)-2-hydroxy-1-phenylpropan-2-yl]-15-methoxy-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-trien-11-ol
Show/Hide
|
C32H39NO4
|
2
|
| 1 |
EC50 = 1.3 nM
|
|
|
| 2 |
Ki = 0.15 nM
|
|
|
|
CP0848722
|
(1'R,5alpha,6R,7R,14alpha)-1'-(3-methylphenyl)-1'-(4,5-epoxy-7,8-dihydro-3-hydroxy-6-methoxy-7beta-methyl 17-cyclopropylmethyl-6,14-etheno-morphinan-7-yl)-methan-1'-ol
Show/Hide
|
C32H37NO4
|
2
|
| 1 |
EC50 = 1.4 nM
|
|
|
| 2 |
Ki = 0.17 nM
|
|
|
|
CP0391787
|
(1S,2S,6R,14R,15R,16R)-5-(cyclopropylmethyl)-16-[(1R)-1-hydroxy-4-methylpentyl]-15-methoxy-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-trien-11-ol
Show/Hide
|
C29H41NO4
|
2
|
| 1 |
EC50 = 1.5 nM
|
|
|
| 2 |
Ki = 0.031 nM
|
|
|
|
CP0446710
|
(2S)-2-amino-N-[(4R)-1-(2-amino-2-oxoethyl)-6-benzyl-3,4-dihydro-2H-quinolin-4-yl]-3-(4-hydroxy-2,6-dimethylphenyl)propanamide
Show/Hide
|
C29H34N4O3
|
2
|
| 1 |
EC50 = 1.5 nM
|
|
|
| 2 |
Ki = 0.23 nM
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|
|
|
CP0382568
|
(2S)-2-amino-N-[(4R)-6-benzyl-1,2,3,4-tetrahydroquinolin-4-yl]-3-(4-hydroxy-2,6-dimethylphenyl)propanamide
Show/Hide
|
C27H31N3O2
|
2
|
| 1 |
EC50 = 1.6 nM
|
|
|
| 2 |
Ki = 0.22 nM
|
|
|
|
CP0888239
|
(S)-2-amino-N-((R)-6-benzyl-1,2,3,4-tetrahydroquinolin-4-yl)-3-(4-hydroxy-2,6-dimethylphenyl)propanamide 2,2,2-trifluoroacetate
Show/Hide
|
C29H32F3N3O4
|
2
|
| 1 |
EC50 = 1.6 nM
|
|
|
| 2 |
Ki = 0.22 nM
|
|
|
|
CP0417748
|
(1S,2S,6R,14R,15R,16R)-16-[(2R)-1-cyclohexyl-2-hydroxypropan-2-yl]-5-(cyclopropylmethyl)-15-methoxy-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-trien-11-ol
Show/Hide
|
C32H45NO4
|
2
|
| 1 |
EC50 = 1.7 nM
|
|
|
| 2 |
Ki = 0.34 nM
|
|
|
|
CP0437786
|
17-Cyclopropylmethyl-3,14beta-dihydroxy-4,5alpha-epoxy-6beta-(cinnamoylamino)morphinan
Show/Hide
|
C29H32N2O4
|
2
|
| 1 |
EC50 = 1.8 nM
|
|
|
| 2 |
Ki = 0.17 nM
|
|
|
|
CP0429424
|
(2S)-2-amino-N-[(4R)-6-benzyl-1-(cyclopropanecarbonyl)-3,4-dihydro-2H-quinolin-4-yl]-3-(4-hydroxy-2,6-dimethylphenyl)propanamide
Show/Hide
|
C31H35N3O3
|
2
|
| 1 |
EC50 = 1.8 nM
|
|
|
| 2 |
Ki = 0.1 nM
|
|
|
|
CP0521687
|
(1S,5S,9R)-5-(3-hydroxyphenyl)-2-[(E)-3-phenylprop-2-enyl]-2-azabicyclo[3.3.1]nonan-9-ol;oxalic acid
Show/Hide
|
C25H29NO6
|
1
|
| 1 |
EC50 = 1.9 nM
|
|
|
|
CP0447075
|
(2S)-N-[(4R)-1-acetyl-6-(1-benzofuran-2-ylmethyl)-3,4-dihydro-2H-quinolin-4-yl]-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanamide;2,2,2-trifluoroacetic acid
Show/Hide
|
C33H34F3N3O6
|
2
|
| 1 |
EC50 = 1.9 nM
|
|
|
| 2 |
Ki = 0.12 nM
|
|
|
|
CP0428155
|
(2E)-N-[(1S,5R,13R,14R,17S)-17-(benzyloxy)-4-(cyclopropylmethyl)-10-hydroxy-12-oxa-4-azapentacyclo[9.6.1.0^{1,13}.0^{5,17}.0^{7,18}]octadeca-7(18),8,10-trien-14-yl]-3-phenylprop-2-enamide
Show/Hide
|
C36H38N2O4
|
2
|
| 1 |
EC50 = 2 nM
|
|
|
| 2 |
Ki = 0.16 nM
|
|
|
|
CP0386996
|
(1S,2S,6R,14R,15R,16R)-16-[(1R)-3-cyclohexyl-1-hydroxypropyl]-5-(cyclopropylmethyl)-15-methoxy-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-trien-11-ol
Show/Hide
|
C32H45NO4
|
2
|
| 1 |
EC50 = 2 nM
|
|
|
| 2 |
Ki = 0.06 nM
|
|
|
|
CP0429476
|
(2E)-N-[(1S,5R,13R,14R,17S)-4-(cyclopropylmethyl)-10,17-dihydroxy-12-oxa-4-azapentacyclo[9.6.1.0^{1,13}.0^{5,17}.0^{7,18}]octadeca-7(18),8,10-trien-14-yl]-3-(2-methoxyphenyl)prop-2-enamide
Show/Hide
|
C30H34N2O5
|
2
|
| 1 |
EC50 = 2.1 nM
|
|
|
| 2 |
Ki = 0.085 nM
|
|
|
|
CP0180848
|
(1S,2S,6R,14R,15R,16R)-5-(cyclopropylmethyl)-16-[(2R)-2-hydroxy-3-methylbutan-2-yl]-15-methoxy-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-trien-11-ol
Show/Hide
|
C28H39NO4
|
2
|
| 1 |
EC50 = 2.1 nM
|
|
|
| 2 |
Ki = 0.15 nM
|
|
|
|
CP0407775
|
(2S)-2-amino-N-[(4R)-6-benzyl-1-(cyclobutanecarbonyl)-3,4-dihydro-2H-quinolin-4-yl]-3-(4-hydroxy-2,6-dimethylphenyl)propanamide
Show/Hide
|
C32H37N3O3
|
2
|
| 1 |
EC50 = 2.1 nM
|
|
|
| 2 |
Ki = 0.23 nM
|
|
|
|
CP0447297
|
(2S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)-N-[(4R)-6-(quinolin-3-ylmethyl)-1,2,3,4-tetrahydroquinolin-4-yl]propanamide;2,2,2-trifluoroacetic acid
Show/Hide
|
C32H33F3N4O4
|
2
|
| 1 |
EC50 = 2.2 nM
|
|
|
| 2 |
Ki = 0.1 nM
|
|
|
|
CP0427080
|
(1S,2S,6R,14R,15R,16R)-16-[(2S)-4-cyclohexyl-2-hydroxybutan-2-yl]-5-(cyclopropylmethyl)-15-methoxy-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-trien-11-ol
Show/Hide
|
C33H47NO4
|
2
|
| 1 |
EC50 = 2.5 nM
|
|
|
| 2 |
Ki = 0.47 nM
|
|
|
|
CP0385128
|
(2S)-2-amino-N-[(4R)-6-(cyclohexylmethyl)-1,2,3,4-tetrahydroquinolin-4-yl]-3-(4-hydroxy-2,6-dimethylphenyl)propanamide
Show/Hide
|
C27H37N3O2
|
2
|
| 1 |
EC50 = 2.6 nM
|
|
|
| 2 |
Ki = 0.043 nM
|
|
|
|
CP0429425
|
(2S)-2-amino-N-[(4R)-1-benzoyl-6-benzyl-3,4-dihydro-2H-quinolin-4-yl]-3-(4-hydroxy-2,6-dimethylphenyl)propanamide
Show/Hide
|
C34H35N3O3
|
2
|
| 1 |
EC50 = 2.6 nM
|
|
|
| 2 |
Ki = 0.08 nM
|
|
|
|
CP0391789
|
(1S,2S,6R,14R,15R,16R)-16-[(1R)-1-cyclopentyl-1-hydroxyethyl]-5-(cyclopropylmethyl)-15-methoxy-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-trien-11-ol
Show/Hide
|
C30H41NO4
|
2
|
| 1 |
EC50 = 2.8 nM
|
|
|
| 2 |
Ki = 0.21 nM
|
|
|
|
CP0418847
|
(1S,2S,6R,14R,15R,16R)-16-[(2R)-4-cyclopentyl-2-hydroxybutan-2-yl]-5-(cyclopropylmethyl)-15-methoxy-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-trien-11-ol
Show/Hide
|
C32H45NO4
|
2
|
| 1 |
EC50 = 2.9 nM
|
|
|
| 2 |
Ki = 0.62 nM
|
|
|
|
CP0385122
|
(2S)-2-amino-N-[(1R)-7-benzyl-1,2,3,4-tetrahydronaphthalen-1-yl]-3-(4-hydroxy-2,6-dimethylphenyl)propanamide
Show/Hide
|
C28H32N2O2
|
2
|
| 1 |
EC50 = 2.9 nM
|
|
|
| 2 |
Ki = 0.045 nM
|
|
|
|
CP0420240
|
(2S)-2-amino-N-[(4R)-6-benzyl-1-(2-methoxyacetyl)-3,4-dihydro-2H-quinolin-4-yl]-3-(4-hydroxy-2,6-dimethylphenyl)propanamide
Show/Hide
|
C30H35N3O4
|
2
|
| 1 |
EC50 = 3 nM
|
|
|
| 2 |
Ki = 0.15 nM
|
|
|
|
CP0382450
|
(2S)-2-amino-N-[(4R)-6-benzyl-1-butanoyl-3,4-dihydro-2H-quinolin-4-yl]-3-(4-hydroxy-2,6-dimethylphenyl)propanamide
Show/Hide
|
C31H37N3O3
|
2
|
| 1 |
EC50 = 3.5 nM
|
|
|
| 2 |
Ki = 0.1 nM
|
|
|
|
CP0420050
|
(2S)-2-amino-N-[(4R)-6-benzyl-1-propanoyl-3,4-dihydro-2H-quinolin-4-yl]-3-(4-hydroxy-2,6-dimethylphenyl)propanamide
Show/Hide
|
C30H35N3O3
|
2
|
| 1 |
EC50 = 3.9 nM
|
|
|
| 2 |
Ki = 0.12 nM
|
|
|
|
CP0482883
|
(2S)-2-amino-N-[(4R)-1-benzoyl-6-(3,4-dihydro-1H-isoquinolin-2-ylmethyl)-3,4-dihydro-2H-quinolin-4-yl]-3-(4-hydroxy-2,6-dimethylphenyl)propanamide;2,2,2-trifluoroacetic acid
Show/Hide
|
C39H41F3N4O5
|
2
|
| 1 |
EC50 = 4.2 nM
|
|
|
| 2 |
Ki = 0.37 nM
|
|
|
|
CP0391785
|
(1S,9R,13S)-10-(cyclopropylmethyl)-1-ethyl-4-hydroxy-13-methyl-10-azatricyclo[7.3.1.02,7]trideca-2(7),3,5-trien-8-one
Show/Hide
|
C19H25NO2
|
1
|
| 1 |
EC50 = 4.4 nM
|
|
|
|
CP0428399
|
(2S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)-N-[(1R)-7-(naphthalen-2-ylmethyl)-1,2,3,4-tetrahydronaphthalen-1-yl]propanamide
Show/Hide
|
C32H34N2O2
|
2
|
| 1 |
EC50 = 4.4 nM
|
|
|
| 2 |
Ki = 0.06 nM
|
|
|
|
CP0391788
|
(1S,2S,6R,14R,15R,16R)-16-[(2R)-4-cyclohexyl-2-hydroxybutan-2-yl]-5-(cyclopropylmethyl)-15-methoxy-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-trien-11-ol
Show/Hide
|
C33H47NO4
|
2
|
| 1 |
EC50 = 4.8 nM
|
|
|
| 2 |
Ki = 1 nM
|
|
|
|
CP0447025
|
(1S,2S,6R,14R,15R,16R)-5-(cyclopropylmethyl)-16-[(2R)-2-hydroxy-4-phenylbutan-2-yl]-15-methoxy-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-trien-11-ol
Show/Hide
|
C33H41NO4
|
2
|
| 1 |
EC50 = 4.9 nM
|
|
|
| 2 |
Ki = 0.32 nM
|
|
|
|
CP0429428
|
ethyl 2-[(4R)-4-[[(2S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanoyl]amino]-6-benzyl-3,4-dihydro-2H-quinolin-1-yl]acetate
Show/Hide
|
C31H37N3O4
|
2
|
| 1 |
EC50 = 5.1 nM
|
|
|
| 2 |
Ki = 0.37 nM
|
|
|
|
CP0385120
|
(2S)-N-[(4R)-1-acetyl-6-benzyl-3,4-dihydro-2H-quinolin-4-yl]-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanamide
Show/Hide
|
C29H33N3O3
|
2
|
| 1 |
EC50 = 6 nM
|
|
|
| 2 |
Ki = 0.13 nM
|
|
|
|
CP0430966
|
(2S)-N-[(4R)-1-acetyl-6-(3,4-dihydro-1H-isoquinolin-2-ylmethyl)-3,4-dihydro-2H-quinolin-4-yl]-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanamide;2,2,2-trifluoroacetic acid
Show/Hide
|
C34H39F3N4O5
|
2
|
| 1 |
EC50 = 6 nM
|
|
|
| 2 |
Ki = 0.19 nM
|
|
|
|
CP0472984
|
(2S)-2-amino-N-[(4R)-1-(cyclopropanecarbonyl)-6-(2,3-dihydro-1,4-benzodioxin-6-ylmethyl)-3,4-dihydro-2H-quinolin-4-yl]-3-(4-hydroxy-2,6-dimethylphenyl)propanamide;2,2,2-trifluoroacetic acid
Show/Hide
|
C35H38F3N3O7
|
2
|
| 1 |
EC50 = 6 nM
|
|
|
| 2 |
Ki = 0.28 nM
|
|
|
|
CP0447294
|
(2S)-2-amino-N-[(4R)-6-(2,3-dihydro-1,4-benzodioxin-6-ylmethyl)-1,2,3,4-tetrahydroquinolin-4-yl]-3-(4-hydroxy-2,6-dimethylphenyl)propanamide;2,2,2-trifluoroacetic acid
Show/Hide
|
C31H34F3N3O6
|
2
|
| 1 |
EC50 = 7.3 nM
|
|
|
| 2 |
Ki = 0.35 nM
|
|
|
|
CP0472986
|
(2S)-2-amino-N-[(4R)-1-benzoyl-6-(naphthalen-2-ylmethyl)-3,4-dihydro-2H-quinolin-4-yl]-3-(4-hydroxy-2,6-dimethylphenyl)propanamide;2,2,2-trifluoroacetic acid
Show/Hide
|
C40H38F3N3O5
|
2
|
| 1 |
EC50 = 7.9 nM
|
|
|
| 2 |
Ki = 0.26 nM
|
|
|
|
CP0385130
|
(2S)-2-amino-N-[(4R)-6-(2,3-dihydro-1H-inden-1-ylmethyl)-1,2,3,4-tetrahydroquinolin-4-yl]-3-(4-hydroxy-2,6-dimethylphenyl)propanamide
Show/Hide
|
C30H35N3O2
|
2
|
| 1 |
EC50 = 9 nM
|
|
|
| 2 |
Ki = 0.05 nM
|
|
|
|
CP0482858
|
(2S)-2-amino-N-[(4R)-6-(2,3-dihydro-1,4-benzodioxin-6-ylmethyl)-1-methylsulfonyl-3,4-dihydro-2H-quinolin-4-yl]-3-(4-hydroxy-2,6-dimethylphenyl)propanamide;2,2,2-trifluoroacetic acid
Show/Hide
|
C32H36F3N3O8S
|
2
|
| 1 |
EC50 = 9 nM
|
|
|
| 2 |
Ki = 0.07 nM
|
|
|
|
CP0419399
|
(2S)-2-amino-N-[(4R)-6-benzyl-1-(2-methylpropanoyl)-3,4-dihydro-2H-quinolin-4-yl]-3-(4-hydroxy-2,6-dimethylphenyl)propanamide
Show/Hide
|
C31H37N3O3
|
2
|
| 1 |
EC50 = 9.6 nM
|
|
|
| 2 |
Ki = 0.38 nM
|
|
|
|
CP0468324
|
(2E)-3-(2-chlorophenyl)-N-[(1S,5R,13R,14R,17S)-4-(cyclopropylmethyl)-10,17-dihydroxy-12-oxa-4-azapentacyclo[9.6.1.0^{1,13}.0^{5,17}.0^{7,18}]octadeca-7(18),8,10-trien-14-yl]prop-2-enamide
Show/Hide
|
C29H31ClN2O4
|
2
|
| 1 |
EC50 = 12 nM
|
|
|
| 2 |
Ki = 0.079 nM
|
|
|
|
CP0451779
|
(2S)-2-amino-N-[(4R)-6-(1-benzofuran-2-ylmethyl)-1-benzoyl-3,4-dihydro-2H-quinolin-4-yl]-3-(4-hydroxy-2,6-dimethylphenyl)propanamide;2,2,2-trifluoroacetic acid
Show/Hide
|
C38H36F3N3O6
|
2
|
| 1 |
EC50 = 12 nM
|
|
|
| 2 |
Ki = 0.35 nM
|
|
|
|
CP0429383
|
(2S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)-N-[(4R)-6-(naphthalen-2-ylmethyl)-1-propanoyl-3,4-dihydro-2H-quinolin-4-yl]propanamide
Show/Hide
|
C34H37N3O3
|
2
|
| 1 |
EC50 = 13 nM
|
|
|
| 2 |
Ki = 0.28 nM
|
|
|
|
CP0472985
|
(2S)-N-[(4R)-1-acetyl-6-(2,3-dihydro-1,4-benzodioxin-6-ylmethyl)-3,4-dihydro-2H-quinolin-4-yl]-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanamide;2,2,2-trifluoroacetic acid
Show/Hide
|
C33H36F3N3O7
|
2
|
| 1 |
EC50 = 13 nM
|
|
|
| 2 |
Ki = 0.38 nM
|
|
|
|
CP0385127
|
(2S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)-N-[(1R)-7-(naphthalen-1-ylmethyl)-1,2,3,4-tetrahydronaphthalen-1-yl]propanamide
Show/Hide
|
C32H34N2O2
|
2
|
| 1 |
EC50 = 14 nM
|
|
|
| 2 |
Ki = 0.39 nM
|
|
|
|
CP0382584
|
(2S)-N-[(4R)-1-acetyl-6-(2,3-dihydro-1H-inden-1-ylmethyl)-3,4-dihydro-2H-quinolin-4-yl]-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanamide
Show/Hide
|
C32H37N3O3
|
2
|
| 1 |
EC50 = 15 nM
|
|
|
| 2 |
Ki = 0.03 nM
|
|
|
|
CP0470601
|
(1R,5R,9S)-5-(3-hydroxyphenyl)-2-[2-[4-(trifluoromethyl)phenyl]ethyl]-2-azabicyclo[3.3.1]nonan-9-ol;hydrochloride
Show/Hide
|
C23H27ClF3NO2
|
1
|
| 1 |
EC50 = 19 nM
|
|
|
|
CP0396057
|
(2S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)-1-[4-[(E)-4-phenylbut-2-enyl]piperazin-1-yl]propan-1-one
Show/Hide
|
C25H33N3O2
|
2
|
| 1 |
EC50 = 20 nM
|
|
|
| 2 |
Ki = 0.29 nM
|
|
|
|
CP0449110
|
(1S,2S,6R,14R,15R,16R)-5-(cyclopropylmethyl)-16-[(1S)-1-hydroxy-3-phenylpropyl]-15-methoxy-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-trien-11-ol
Show/Hide
|
C32H39NO4
|
2
|
| 1 |
EC50 = 21 nM
|
|
|
| 2 |
Ki = 0.029 nM
|
|
|
|
CP0372433
|
(1R,5R,9S)-(-)-9-hydroxy-5-(3-hydroxyphenyl-2-phenylethyl-2-azabicyclo[3.3.1]nonane
Show/Hide
|
C22H27NO2
|
1
|
| 1 |
EC50 = 22 nM
|
|
|
|
CP0392519
|
(2S)-2-amino-N-[(4R)-6-benzyl-1,2,3,4-tetrahydroquinolin-4-yl]-3-(2,6-dichloro-4-hydroxyphenyl)propanamide
Show/Hide
|
C25H25Cl2N3O2
|
2
|
| 1 |
EC50 = 33 nM
|
|
|
| 2 |
Ki = 0.47 nM
|
|
|
|
CP0404433
|
(2S)-2-amino-N-[(4R)-6-benzyl-1,2,3,4-tetrahydroquinolin-4-yl]-3-(4-hydroxy-2,5-dimethylphenyl)propanamide
Show/Hide
|
C27H31N3O2
|
2
|
| 1 |
EC50 = 39 nM
|
|
|
| 2 |
Ki = 6.5 nM
|
|
|
|
CP0421079
|
(2S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)-1-[4-[(Z)-4-phenylbut-2-enyl]piperazin-1-yl]propan-1-one
Show/Hide
|
C25H33N3O2
|
2
|
| 1 |
EC50 = 41 nM
|
|
|
| 2 |
Ki = 0.3 nM
|
|
|
|
CP0400891
|
(2S)-2-amino-N-[(4R)-6-benzyl-1,2,3,4-tetrahydroquinolin-4-yl]-3-(4-hydroxy-2-methylphenyl)propanamide
Show/Hide
|
C26H29N3O2
|
2
|
| 1 |
EC50 = 44 nM
|
|
|
| 2 |
Ki = 1.7 nM
|
|
|
|
CP0412223
|
(2S)-2-amino-N-[(1R)-1-(3-benzylphenyl)ethyl]-3-(4-hydroxy-2,6-dimethylphenyl)propanamide;2,2,2-trifluoroacetic acid
Show/Hide
|
C28H31F3N2O4
|
2
|
| 1 |
EC50 = 44.4 nM
|
|
|
| 2 |
Ki = 1.1 nM
|
|
|
|
CP0432505
|
(2S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)-1-[4-(5-phenylpentyl)piperazin-1-yl]propan-1-one
Show/Hide
|
C26H37N3O2
|
2
|
| 1 |
EC50 = 53 nM
|
|
|
| 2 |
Ki = 0.42 nM
|
|
|
|
CP0432506
|
(2S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)-1-[4-(4-phenylbutyl)piperazin-1-yl]propan-1-one
Show/Hide
|
C25H35N3O2
|
2
|
| 1 |
EC50 = 64 nM
|
|
|
| 2 |
Ki = 0.45 nM
|
|
|
|
CP0412205
|
(2S)-2-amino-N-[(5-benzyl-2-propoxyphenyl)methyl]-3-(4-hydroxy-2,6-dimethylphenyl)propanamide;2,2,2-trifluoroacetic acid
Show/Hide
|
C30H35F3N2O5
|
2
|
| 1 |
EC50 = 68 nM
|
|
|
| 2 |
Ki = 0.91 nM
|
|
|
|
CP0402366
|
(2S)-2-amino-N-[[5-benzyl-2-(cyclopropylmethoxy)phenyl]methyl]-3-(4-hydroxy-2,6-dimethylphenyl)propanamide;2,2,2-trifluoroacetic acid
Show/Hide
|
C31H35F3N2O5
|
2
|
| 1 |
EC50 = 71 nM
|
|
|
| 2 |
Ki = 2.7 nM
|
|
|
|
CP0849802
|
(S)-1-((5-Benzyl-2-ethoxybenzyl)amino)-3-(4-hydroxy-2,6-dimethylphenyl)-1-oxopropan-2-aminium Trifluoroacetate
Show/Hide
|
C29H33F3N2O5
|
2
|
| 1 |
EC50 = 77 nM
|
|
|
| 2 |
Ki = 2.8 nM
|
|
|
|
CP0419423
|
2-[(4R)-4-[[(2S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanoyl]amino]-6-benzyl-3,4-dihydro-2H-quinolin-1-yl]acetic acid
Show/Hide
|
C29H33N3O4
|
2
|
| 1 |
EC50 = 78 nM
|
|
|
| 2 |
Ki = 4.4 nM
|
|
|
|
CP0412199
|
(2S)-2-amino-N-[[5-benzyl-2-(propanoylamino)phenyl]methyl]-3-(4-hydroxy-2,6-dimethylphenyl)propanamide;2,2,2-trifluoroacetic acid
Show/Hide
|
C30H34F3N3O5
|
2
|
| 1 |
EC50 = 84 nM
|
|
|
| 2 |
Ki = 4.2 nM
|
|
|
|
CP0457352
|
(2S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)-1-[4-(3-naphthalen-1-ylpropyl)piperazin-1-yl]propan-1-one
Show/Hide
|
C28H35N3O2
|
2
|
| 1 |
EC50 = 85 nM
|
|
|
| 2 |
Ki = 1.1 nM
|
|
|
|
CP0416993
|
(2S)-2-amino-N-[(5-benzyl-2-phenylmethoxyphenyl)methyl]-3-(4-hydroxy-2,6-dimethylphenyl)propanamide;2,2,2-trifluoroacetic acid
Show/Hide
|
C34H35F3N2O5
|
2
|
| 1 |
EC50 = 107 nM
|
|
|
| 2 |
Ki = 8 nM
|
|
|
|
CP0402374
|
(2S)-2-amino-N-[(5-benzyl-2-methylphenyl)methyl]-3-(4-hydroxy-2,6-dimethylphenyl)propanamide;2,2,2-trifluoroacetic acid
Show/Hide
|
C28H31F3N2O4
|
2
|
| 1 |
EC50 = 111 nM
|
|
|
| 2 |
Ki = 5.2 nM
|
|
|
|
CP0484176
|
(2S)-N-[(2-acetamido-5-benzylphenyl)methyl]-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanamide;2,2,2-trifluoroacetic acid
Show/Hide
|
C29H32F3N3O5
|
2
|
| 1 |
EC50 = 117 nM
|
|
|
| 2 |
Ki = 7.9 nM
|
|
|
|
CP0457353
|
(2S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)-1-[4-(3-phenylpropyl)piperidin-1-yl]propan-1-one
Show/Hide
|
C25H34N2O2
|
2
|
| 1 |
EC50 = 119 nM
|
|
|
| 2 |
Ki = 2 nM
|
|
|
|
CP0043301
|
(2S)-2-{2-[(2R)-2-[(2S)-2-amino-3-(4-hydroxyphenyl)propanamido]propanamido]-N-methylacetamido}-N-(2-hydroxyethyl)-3-phenylpropanamide
Show/Hide
|
C26H35N5O6
|
1
|
| 1 |
EC50 = 146 nM
|
|
|
|
CP0379924
|
(2S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)-1-[4-(3-phenylpropyl)piperazin-1-yl]propan-1-one
Show/Hide
|
C24H33N3O2
|
2
|
| 1 |
EC50 = 150 nM
|
|
|
| 2 |
Ki = 3.8 nM
|
|
|
|
CP0412222
|
(2S)-2-amino-N-[[5-benzyl-2-(ethylamino)phenyl]methyl]-3-(4-hydroxy-2,6-dimethylphenyl)propanamide;2,2,2-trifluoroacetic acid
Show/Hide
|
C29H34F3N3O4
|
2
|
| 1 |
EC50 = 156 nM
|
|
|
| 2 |
Ki = 23.5 nM
|
|
|
|
CP0468852
|
(2S)-2-amino-N-[(1R)-1-(3-benzylphenyl)propyl]-3-(4-hydroxy-2,6-dimethylphenyl)propanamide;2,2,2-trifluoroacetic acid
Show/Hide
|
C29H33F3N2O4
|
2
|
| 1 |
EC50 = 158 nM
|
|
|
| 2 |
Ki = 3.2 nM
|
|
|
|
CP0000305
|
(-)-(etorphine)
Show/Hide
|
C17H19NO3
|
3
|
| 1 |
EC50 = 194 nM
|
|
|
| 2 |
Ki = 6.3 nM
|
|
|
| 3 |
Ki = 6.55 nM
|
|
|
|
CP0416992
|
(2S)-2-amino-N-[(5-benzyl-2-chlorophenyl)methyl]-3-(4-hydroxy-2,6-dimethylphenyl)propanamide;2,2,2-trifluoroacetic acid
Show/Hide
|
C27H28ClF3N2O4
|
2
|
| 1 |
EC50 = 250 nM
|
|
|
| 2 |
Ki = 5.6 nM
|
|
|
|
CP0412224
|
(2S)-2-amino-N-[(5-benzyl-2-methoxyphenyl)methyl]-3-(4-hydroxy-2,6-dimethylphenyl)propanamide;2,2,2-trifluoroacetic acid
Show/Hide
|
C28H31F3N2O5
|
2
|
| 1 |
EC50 = 264 nM
|
|
|
| 2 |
Ki = 3.58 nM
|
|
|
|
CP0392521
|
(2S)-2-amino-N-[(4R)-6-benzyl-1,2,3,4-tetrahydroquinolin-4-yl]-3-(2,6-dimethylphenyl)propanamide
Show/Hide
|
C27H31N3O
|
2
|
| 1 |
EC50 = 280 nM
|
|
|
| 2 |
Ki = 18 nM
|
|
|
|
CP0383080
|
(2S)-2-amino-N-[(1R)-1-(5-benzyl-2-methoxyphenyl)ethyl]-3-(4-hydroxy-2,6-dimethylphenyl)propanamide;2,2,2-trifluoroacetic acid
Show/Hide
|
C29H33F3N2O5
|
2
|
| 1 |
EC50 = 296 nM
|
|
|
| 2 |
Ki = 8 nM
|
|
|
|
CP0416998
|
(2S)-2-amino-N-[[5-benzyl-2-(trifluoromethoxy)phenyl]methyl]-3-(4-hydroxy-2,6-dimethylphenyl)propanamide;2,2,2-trifluoroacetic acid
Show/Hide
|
C28H28F6N2O5
|
2
|
| 1 |
EC50 = 342 nM
|
|
|
| 2 |
Ki = 1.4 nM
|
|
|
|
CP0412225
|
(2S)-2-amino-N-[(5-benzyl-2-hydroxyphenyl)methyl]-3-(4-hydroxy-2,6-dimethylphenyl)propanamide;2,2,2-trifluoroacetic acid
Show/Hide
|
C27H29F3N2O5
|
2
|
| 1 |
EC50 = 552 nM
|
|
|
| 2 |
Ki = 9.48 nM
|
|
|
|
CP0470604
|
(1R,5R,9R)-5-(3-hydroxyphenyl)-2-[[(1R,2S)-2-phenylcyclopropyl]methyl]-2-azabicyclo[3.3.1]nonan-9-ol;oxalic acid
Show/Hide
|
C26H31NO6
|
1
|
| 1 |
EC50 = 797.1 nM
|
|
|
|
CP0475123
|
(1R,5R,9S)-5-(3-hydroxyphenyl)-2-prop-2-enyl-2-azabicyclo[3.3.1]nonan-9-ol;hydrochloride
Show/Hide
|
C17H24ClNO2
|
1
|
| 1 |
EC50 = 2056 nM
|
|
|
|
CP0385125
|
(2S)-2-amino-N-[(1R)-7-(cyclohexylmethyl)-1,2,3,4-tetrahydronaphthalen-1-yl]-3-(4-hydroxy-2,6-dimethylphenyl)propanamide
Show/Hide
|
C28H38N2O2
|
1
|
| 1 |
Ki = 0.012 nM
|
|
|
|
CP0045401
|
(5R,8S,11S,14S)-14-((S)-2-amino-3-(4-hydroxyphenyl)propanamido)-8,11-dibenzyl-7,10,13-trioxo-1,3-dithia-6,9,12-triazacyclopentadecane-5-carboxamide
Show/Hide
|
C34H40N6O6S2
|
1
|
| 1 |
Ki = 0.016 nM
|
|
|
|
CP0126886
|
(4R,4aS,7aR,12bR)-9-hydroxy-4a-methoxy-3,7a-dimethyl-1,2,4,5,6,13-hexahydro-4,12-methanobenzofuro[3,2-e]isoquinolin-7-one
Show/Hide
|
C19H23NO4
|
1
|
| 1 |
Ki = 0.023 nM
|
|
|
|
CP0247469
|
(1S,2S,6R,14R,15R,16R)-5-(cyclopropylmethyl)-16-[(1R)-1-hydroxy-3-phenylpropyl]-15-methoxy-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-trien-11-ol
Show/Hide
|
C32H39NO4
|
1
|
| 1 |
Ki = 0.029 nM
|
|
|
|
CP0385503
|
(1S,2S,6R,14R,15R,16R)-16-[(R)-(3-chlorophenyl)-hydroxymethyl]-5-(cyclopropylmethyl)-15-methoxy-16-methyl-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-trien-11-ol
Show/Hide
|
C31H36ClNO4
|
1
|
| 1 |
Ki = 0.052 nM
|
|
|
|
CP0144175
|
(1S,2S,6R,14R,15R,16R)-5-(cyclopropylmethyl)-16-[(1R)-1-hydroxy-3-methylbutyl]-15-methoxy-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-trien-11-ol
Show/Hide
|
C28H39NO4
|
1
|
| 1 |
Ki = 0.054 nM
|
|
|
|
CP0414678
|
(1S,2S,6R,14R,15R,16R)-5-(cyclopropylmethyl)-16-[(R)-(4-fluorophenyl)-hydroxymethyl]-15-methoxy-16-methyl-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-trien-11-ol
Show/Hide
|
C31H36FNO4
|
1
|
| 1 |
Ki = 0.071 nM
|
|
|
|
CP0452451
|
(4R,7S,10S,13S)-13-((S)-2-amino-3-(4-hydroxyphenyl)propanamido)-7-benzyl-10-(naphthalen-1-ylmethyl)-6,9,12-trioxo-1,2-dithia-5,8,11-triazacyclotetradecane-4-carboxamide
Show/Hide
|
C37H40N6O6S2
|
1
|
| 1 |
Ki = 0.08 nM
|
|
|
|
CP0850661
|
(1'R,5alpha,6R,7R,14alpha)-1'-phenyl-1'-(4,5-epoxy-7,8-dihydro-3-hydroxy-6-methoxy-7beta-methyl 17-cyclopropylmethyl-6,14-ethenomorphinan-7-yl)-methan-1'-ol
Show/Hide
|
C31H35NO4
|
1
|
| 1 |
Ki = 0.08 nM
|
|
|
|
CP0910158
|
10-hydroxy-17-(3-phenylpropoxy)-4-propyl-(13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7,9,11(18)-trien-14-one
Show/Hide
|
C28H33NO4
|
1
|
| 1 |
Ki = 0.09 nM
|
|
|
|
CP0385505
|
(1S,2S,6R,14R,15R,16R)-5-(cyclopropylmethyl)-16-[(R)-(3-fluorophenyl)-hydroxymethyl]-15-methoxy-16-methyl-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-trien-11-ol
Show/Hide
|
C31H36FNO4
|
1
|
| 1 |
Ki = 0.09 nM
|
|
|
|
CP0385500
|
(1S,2S,6R,14R,15R,16R)-5-(cyclopropylmethyl)-16-[(R)-hydroxy-(3-methylphenyl)methyl]-15-methoxy-16-methyl-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-trien-11-ol
Show/Hide
|
C32H39NO4
|
1
|
| 1 |
Ki = 0.098 nM
|
|
|
|
CP0380849
|
(1S,2S,6R,14R,15R,16R)-5-(cyclopropylmethyl)-16-[(R)-hydroxy(phenyl)methyl]-15-methoxy-16-methyl-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-trien-11-ol
Show/Hide
|
C31H37NO4
|
1
|
| 1 |
Ki = 0.1 nM
|
|
|
|
CP0380850
|
(1S,2S,6R,14R,15R,16R)-5-(cyclopropylmethyl)-16-[(R)-furan-3-yl(hydroxy)methyl]-15-methoxy-16-methyl-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-trien-11-ol
Show/Hide
|
C29H35NO5
|
1
|
| 1 |
Ki = 0.11 nM
|
|
|
|
CP0415110
|
(1S,2S,6R,14R,15R,16R)-5-(cyclopropylmethyl)-16-[(R)-hydroxy-(4-methylphenyl)methyl]-15-methoxy-16-methyl-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-trien-11-ol
Show/Hide
|
C32H39NO4
|
1
|
| 1 |
Ki = 0.14 nM
|
|
|
|
CP0382350
|
(1S,2S,6R,14R,15R,16R)-5-(cyclopropylmethyl)-16-[(1R)-1-hydroxy-1-pyridin-4-ylethyl]-15-methoxy-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-trien-11-ol
Show/Hide
|
C30H36N2O4
|
1
|
| 1 |
Ki = 0.16 nM
|
|
|
|
CP0395432
|
(1S,2S,6R,14R,15R,16R)-5-(cyclopropylmethyl)-16-[(1S)-1-hydroxy-1-phenylethyl]-15-methoxy-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-trien-11-ol
Show/Hide
|
C31H37NO4
|
1
|
| 1 |
Ki = 0.17 nM
|
|
|
|
CP0404998
|
(1S,2S,6R,14R,15R,16R)-5-(cyclopropylmethyl)-16-[(1S)-1-hydroxy-1-(2-methylphenyl)ethyl]-15-methoxy-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-trien-11-ol
Show/Hide
|
C32H39NO4
|
1
|
| 1 |
Ki = 0.19 nM
|
|
|
|
CP0499509
|
US10231963, Table B.13
Show/Hide
|
C28H31NO4
|
1
|
| 1 |
Ki = 0.2 nM
|
|
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CP0846973
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10-hydroxy-17-(3-phenylpropoxy)-4-tetrahydro-2-furanylmethyl-(13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7,9,11(18)-trien-14-one
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C30H35NO5
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1
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| 1 |
Ki = 0.2 nM
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CP0415112
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(1S,2S,6R,14R,15R,16R)-5-(cyclopropylmethyl)-16-[(R)-hydroxy-(2-methylphenyl)methyl]-15-methoxy-16-methyl-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-trien-11-ol
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C32H39NO4
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1
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| 1 |
Ki = 0.2 nM
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CP0847461
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4-cyclobutylmethyl-10-hydroxy-17-(3-phenylpropoxy)-(13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7,9,11(18)-trien-14-one
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C30H35NO4
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1
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| 1 |
Ki = 0.25 nM
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CP0395431
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(1S,2S,6R,14R,15R,16R)-5-(cyclopropylmethyl)-16-[(1S)-1-(3,5-dimethylphenyl)-1-hydroxyethyl]-15-methoxy-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-trien-11-ol
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C33H41NO4
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1
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| 1 |
Ki = 0.28 nM
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CP0418175
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(5R,8S,11S,14S)-14-((S)-2-amino-3-(4-hydroxyphenyl)propanamido)-8-benzyl-11-(naphthalen-1-ylmethyl)-7,10,13-trioxo-1,3-dithia-6,9,12-triazacyclopentadecane-5-carboxamide
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C38H42N6O6S2
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1
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| 1 |
Ki = 0.33 nM
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CP0437789
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14-O-phenylpropylnaltrexone
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C29H33NO4
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1
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| 1 |
Ki = 0.34 nM
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CP0428157
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(1S,5R,13R,14R,17S)-4-(cyclopropylmethyl)-10-hydroxy-14-[(2E)-3-phenylprop-2-enamido]-12-oxa-4-azapentacyclo[9.6.1.0^{1,13}.0^{5,17}.0^{7,18}]octadeca-7(18),8,10-trien-17-yl benzoate
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C36H36N2O5
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1
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| 1 |
Ki = 0.42 nM
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CP0452452
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(5R,8S,11S,14S)-14-((S)-2-amino-3-(4-hydroxyphenyl)propanamido)-8-benzyl-11-(naphthalen-2-ylmethyl)-7,10,13-trioxo-1,3-dithia-6,9,12-triazacyclopentadecane-5-carboxamide
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C38H42N6O6S2
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1
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| 1 |
Ki = 0.47 nM
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CP0413167
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(1S,2S,6R,14R,15R,16R)-5-(cyclopropylmethyl)-16-[(1S)-1-hydroxy-1-thiophen-2-ylethyl]-15-methoxy-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-trien-11-ol
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C29H35NO4S
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1
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| 1 |
Ki = 0.6 nM
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CP0447314
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(5R,8S,11S,14S)-14-((S)-2-amino-3-(4-hydroxyphenyl)propanamido)-11-benzyl-8-(naphthalen-1-ylmethyl)-7,10,13-trioxo-1,3-dithia-6,9,12-triazacyclopentadecane-5-carboxamide
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C38H42N6O6S2
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1
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| 1 |
Ki = 0.61 nM
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CP0470368
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(4R,7S,10S,13S)-13-((S)-2-amino-3-(4-hydroxyphenyl)propanamido)-7-benzyl-10-(naphthalen-2-ylmethyl)-6,9,12-trioxo-1,2-dithia-5,8,11-triazacyclotetradecane-4-carboxamide
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C37H40N6O6S2
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1
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| 1 |
Ki = 0.72 nM
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CP0385293
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(1S,2S,6R,14R,15R,16R)-5-(cyclopropylmethyl)-16-[(1S)-1-hydroxy-2-methylpropyl]-15-methoxy-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-trien-11-ol
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C27H37NO4
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1
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| 1 |
Ki = 0.88 nM
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CP0416997
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(2S)-2-amino-N-[(3-benzylphenyl)methyl]-3-(4-hydroxy-2,6-dimethylphenyl)propanamide;2,2,2-trifluoroacetic acid
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C27H29F3N2O4
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1
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| 1 |
Ki = 1 nM
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CP0869549
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10-hydroxy-4-phenethyl-17-(3-phenylpropoxy)-(13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7,9,11(18)-trien-14-one
Show/Hide
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C33H35NO4
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1
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| 1 |
Ki = 1.1 nM
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CP0457351
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(2S)-2-amino-1-[4-(3,3-diphenylpropyl)piperazin-1-yl]-3-(4-hydroxy-2,6-dimethylphenyl)propan-1-one
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C30H37N3O2
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1
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| 1 |
Ki = 1.1 nM
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CP0470384
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(4R,7S,10S,13S)-13-((S)-2-amino-3-(4-hydroxyphenyl)propanamido)-10-benzyl-7-(naphthalen-2-ylmethyl)-6,9,12-trioxo-1,2-dithia-5,8,11-triazacyclotetradecane-4-carboxamide
Show/Hide
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C37H40N6O6S2
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1
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| 1 |
Ki = 1.2 nM
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CP0443502
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(2S)-2-amino-1-(4-benzylpiperidin-1-yl)-3-(4-hydroxy-2,6-dimethylphenyl)propan-1-one
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C23H30N2O2
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1
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| 1 |
Ki = 1.4 nM
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CP0472987
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(2S)-2-amino-N-[(4R)-1-benzoyl-6-(2,3-dihydro-1,4-benzodioxin-6-ylmethyl)-3,4-dihydro-2H-quinolin-4-yl]-3-(4-hydroxy-2,6-dimethylphenyl)propanamide;2,2,2-trifluoroacetic acid
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C38H38F3N3O7
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1
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| 1 |
Ki = 1.5 nM
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CP0448772
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(2S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)-N-[(4S)-6-(naphthalen-2-ylmethyl)-1,2,3,4-tetrahydroquinolin-4-yl]propanamide
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C31H33N3O2
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1
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| 1 |
Ki = 1.6 nM
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CP0871267
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10-methoxy-4-phenethyl-17-(3-phenylpropoxy)-(13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7,9,11(18)-trien-14-one
Show/Hide
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C34H37NO4
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1
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| 1 |
Ki = 1.9 nM
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CP0458898
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(4R,7S,10S,13S)-13-((S)-2-amino-3-(4-hydroxyphenyl)propanamido)-10-benzyl-7-(naphthalen-1-ylmethyl)-6,9,12-trioxo-1,2-dithia-5,8,11-triazacyclotetradecane-4-carboxamide
Show/Hide
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C37H40N6O6S2
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1
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| 1 |
Ki = 2.5 nM
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CP0459878
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(2S)-2-amino-N-[(4S)-6-benzyl-1,2,3,4-tetrahydroquinolin-4-yl]-3-(4-hydroxy-2,6-dimethylphenyl)propanamide
Show/Hide
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C27H31N3O2
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1
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| 1 |
Ki = 2.6 nM
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CP0870134
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10-methoxy-17-(3-phenylpropoxy)-4-tetrahydro-2-furanylmethyl-(13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7,9,11(18)-trien-14-one
Show/Hide
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C31H37NO5
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1
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| 1 |
Ki = 3.8 nM
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CP0432508
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(2S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)-1-[4-[(E)-3-naphthalen-1-ylprop-2-enyl]piperazin-1-yl]propan-1-one
Show/Hide
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C28H33N3O2
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1
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| 1 |
Ki = 6.4 nM
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CP0410857
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(2S)-2-amino-N-[(4S)-6-(2,3-dihydro-1H-inden-2-ylmethyl)-1,2,3,4-tetrahydroquinolin-4-yl]-3-(4-hydroxy-2,6-dimethylphenyl)propanamide
Show/Hide
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C30H35N3O2
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1
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| 1 |
Ki = 8 nM
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CP0410856
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(2S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)-N-[(4S)-6-(2-phenylethyl)-1,2,3,4-tetrahydroquinolin-4-yl]propanamide
Show/Hide
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C28H33N3O2
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1
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| 1 |
Ki = 16 nM
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CP0379925
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(2S)-2-amino-1-(4-benzyl-3,4-dihydro-2H-quinolin-1-yl)-3-(4-hydroxy-2,6-dimethylphenyl)propan-1-one
Show/Hide
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C27H30N2O2
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1
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| 1 |
Ki = 29 nM
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CP0378305
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(1R,13S,14R)-24-(cyclopropylmethyl)-20-methoxy-4,24-diazahexacyclo[12.7.3.0^{1,13}.0^{3,11}.0^{5,10}.0^{16,21}]tetracosa-3(11),5(10),6,8,16,18,20-heptaene-13,19-diol
Show/Hide
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C27H30N2O3
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1
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| 1 |
Ki = 58 nM
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CP0893297
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oxymorphindole hydrochloride
Show/Hide
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C23H23ClN2O3
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1
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| 1 |
Ki = 105 nM
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CP0456604
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(2S)-2-amino-N-[(4R)-6-benzyl-1,2,3,4-tetrahydroquinolin-4-yl]-3-(8-hydroxynaphthalen-2-yl)propanamide
Show/Hide
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C29H29N3O2
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1
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| 1 |
Ki = 440 nM
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CP0378307
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(1R,13S,14R)-20-methoxy-24-methyl-4,24-diazahexacyclo[12.7.3.0^{1,13}.0^{3,11}.0^{5,10}.0^{16,21}]tetracosa-3(11),5(10),6,8,16,18,20-heptaene-13,19-diol
Show/Hide
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C24H26N2O3
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1
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| 1 |
Ki = 474 nM
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CP0371759
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(1R,13S,14R)-24-(cyclopropylmethyl)-19,20-dimethoxy-4,24-diazahexacyclo[12.7.3.0^{1,13}.0^{3,11}.0^{5,10}.0^{16,21}]tetracosa-3(11),5(10),6,8,16,18,20-heptaen-13-ol
Show/Hide
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C28H32N2O3
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1
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| 1 |
Ki = 1720 nM
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CP0453799
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(1R,13S,14R)-19,20-dimethoxy-24-methyl-4,24-diazahexacyclo[12.7.3.0^{1,13}.0^{3,11}.0^{5,10}.0^{16,21}]tetracosa-3(11),5(10),6,8,16,18,20-heptaen-13-ol
Show/Hide
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C25H28N2O3
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1
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| 1 |
Ki = 7590 nM
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