General Information of the Compound
| Compound ID |
CP0043301
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| Compound Name |
(2S)-2-{2-[(2R)-2-[(2S)-2-amino-3-(4-hydroxyphenyl)propanamido]propanamido]-N-methylacetamido}-N-(2-hydroxyethyl)-3-phenylpropanamide
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| Synonyms |
(D-Ala(2)-mephe(4)-gly-ol(5))enkephalin
2-Ala-4-mephe-5-gly-enkephalin
78123-71-4
Ala(2)-mephe(4)-gly-ol(5) enkephalin
CHEBI:272
CHEMBL38874
DAGO
DAMGE
DAMGO
Dagol
Enkephalin, Ala(2)-MePhe(4)-Gly-ol(5)-
Enkephalin, ala(2)-mephe(4)-gly(5)-
Enkephalin, alanyl(2)-methylphenylalanyl(4)-glycine(5)-
H-Tyr-D-Ala-Gly-N-Me-Phe-Glycinol
L-Phenylalaninamide, L-tyrosyl-D-alanylglycyl-N-(2-hydroxyethyl)-Nalpha-methyl-
RX 783006
Tyr-D-Ala-Gly-MePhe-Gly-ol
Tyr-ala-gly-(nme)phe-gly-ol
[3H]DAMGO
glyol
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| Structure |
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| Formula |
C26H35N5O6
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| Molecular Weight |
513.595
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| Canonical SMILES |
C[C@@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)NCC(=O)N(C)[C@@H](Cc1ccccc1)C(=O)NCCO
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| InChI |
InChI=1S/C26H35N5O6/c1-17(30-25(36)21(27)14-19-8-10-20(33)11-9-19)24(35)29-16-23(34)31(2)22(26(37)28-12-13-32)15-18-6-4-3-5-7-18/h3-11,17,21-22,32-33H,12-16,27H2,1-2H3,(H,28,37)(H,29,35)(H,30,36)/t17-,21+,22+/m1/s1
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| InChIKey |
HPZJMUBDEAMBFI-WTNAPCKOSA-N
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| CAS |
78123-71-4
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01200, Delta-type opioid receptor
Cell-based Assay
Protein ID: PT01526, Delta-type opioid receptor
Protein ID: PT01791, Delta-type opioid receptor
Protein ID: PT01124, Gastrin/cholecystokinin type B receptor
Protein ID: PT00983, Kappa-type opioid receptor
Cell-based Assay
Protein ID: PT01549, Mu-type opioid receptor
Cell-based Assay
Protein ID: PT01515, Mu-type opioid receptor
Cell-based Assay
Protein ID: PT02699, Mu-type opioid receptor
Protein ID: PT01360, Nociceptin receptor
Clinical Information about the Compound