Protein Information

General Information of the Protein

Protein ID	PT01791
Protein Name	Delta-type opioid receptor
Secondarily Protein Name	K56 MSL-2
Gene Name	OPRD1
Sequence	MELVPSARAELQSSPLVNLSDAFPSAFPSAGANASGSPGARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYTKLKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVGVPIMVMAVTQPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDINRRDPLVVAALHLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRTPCGRQEPGSLRRPRQATTRERVTACTPSDGPGGGAAA Show/Hide
Organism	Mus musculus, Mouse
Protein Classification	Membrane receptor > Family A G protein-coupled receptor > Peptide receptor (family A GPCR) > Short peptide receptor (family A GPCR) > Opioid receptor
Function	G-protein coupled receptor that functions as a receptor for endogenous enkephalins and for a subset of other opioids. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling leads to the inhibition of adenylate cyclase activity. Inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. Plays a role in the perception of pain and in opiate-mediated analgesia. Plays a role in developing analgesic tolerance to morphine. Show/Hide
Uniprot ID	P32300
Ensembl ID	ENSG00000116329
Subcellular Location	Cell membrane

Map of Molecular Bioactivity Related to the Protein

Map of Molecular Bioactivity Related to the Protein Protein Cell Line Compound Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity

Table of Molecular Bioactivities Related to the Protein

Cell Line ID: CL000011 , CHO

Cell Line Info

Compound ID	Compound Name	Compound Formula
CP0190770 Compound Info	methyl (E)-2-[(2S,6'S,7'S,8'aS)-6'-ethyl-3-oxo-4-phenylspiro[1H-indole-2,1'-3,5,6,7,8,8a-hexahydro-2H-indolizine]-7'-yl]-3-methoxyprop-2-enoate Show/Hide	C28H32N2O4	2
1	EC50 = 0.83 nM Bioactivity Info	TI LI LO TS
2	Ki = 0.8 nM Bioactivity Info	TI LI LO TS
CP0038418 Compound Info	13-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-7-benzyl-3,3,14,14-tetramethyl-6,9,12-trioxo-1,2-dithia-5,8,11-triaza-cyclotetradecane-4-carboxylic acid Show/Hide	C30H39N5O7S2	1
1	EC50 = 2.05 nM Bioactivity Info	TI LI LO TS
CP0048724 Compound Info	(4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-bis(oxidanyl)-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-one;hydrochloride Show/Hide	C20H23NO4	2
1	EC50 = 4.4 nM Bioactivity Info	TI LI LO TS
2	Ki = 143.5 nM Bioactivity Info	TI LI LO TS
CP0328410 Compound Info	(2S)-2-amino-N-[(4S,10S,15S,21S)-21-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-10,15-dibenzyl-3,3,22,22-tetramethyl-5,8,11,14,17,20-hexaoxo-1,2-dithia-6,9,12,13,16,19-hexazacyclodocos-4-yl]-3-(4-hydroxyphenyl)propanamide Show/Hide	C50H62N10O10S2	1
1	EC50 = 7.1 nM Bioactivity Info	TI LI LO TS
CP0523415 Compound Info	(4S)-4-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]propanoyl]amino]-3-phenylpropanoyl]amino]-5-[[(2S,3S)-1-[[(2S,3S)-1-(carboxymethylamino)-3-methyl-1-oxopentan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-5-oxopentanoic acid Show/Hide	C40H57N7O11	1
1	EC50 = 7.7 nM Bioactivity Info	TI LI LO TS
CP0379613 Compound Info	(E)-N-[(4R,4aR,7R,7aR,12bS)-9-hydroxy-3-methyl-2,4,4a,7,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7-yl]-3-phenylprop-2-enamide Show/Hide	C26H26N2O3	2
1	EC50 = 9.1 nM Bioactivity Info	TI LI LO TS
2	Ki = 10.26 nM Bioactivity Info	TI LI LO TS
CP0216238 Compound Info	(4S,7S,13S)-13-[(2S)-2-amino-3-(4-hydroxyphenyl)propanamido]-7-benzyl-3,3,14,14-tetramethyl-6,9,12-trioxo-1,2-dithia-5,8,11-triazacyclotetradecane-4-carboxylic acid Show/Hide	C30H39N5O7S2	1
1	EC50 = 10 nM Bioactivity Info	TI LI LO TS
CP0386575 Compound Info	N-[(4R,4aS,7S,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-dihydroxy-1,2,4,5,6,7,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinolin-7-yl]-1-chloro-4-methoxyisoquinoline-3-carboxamide Show/Hide	C31H32ClN3O5	2
1	EC50 = 32.6 nM Bioactivity Info	TI LI LO TS
2	Ki = 33.9 nM Bioactivity Info	TI LI LO TS
CP0045380 Compound Info	(2S)-2-amino-N-[(1R)-1-[({[(1S)-1-{N'-[(2S)-2-{2-[(2R)-2-[(2S)-2-amino-3-(4-hydroxyphenyl)propanamido]propanamido]acetamido}-3-phenylpropanoyl]hydrazinecarbonyl}-2-phenylethyl]carbamoyl}methyl)carbamoyl]ethyl]-3-(4-hydroxyphenyl)propanamide Show/Hide	C46H56N10O10	1
1	EC50 = 90.5 nM Bioactivity Info	TI LI LO TS
CP0370812 Compound Info	17-Cyclopropylmethyl-3,14beta-dihydroxy-4,5r-epoxy-6alpha-[(3'-isoquinolyl)acetamido]morphinan Show/Hide	C30H31N3O4	2
1	EC50 = 98.6 nM Bioactivity Info	TI LI LO TS
2	Ki = 161.9 nM Bioactivity Info	TI LI LO TS
CP0379351 Compound Info	N-[(4R,4aS,7S,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-dihydroxy-1,2,4,5,6,7,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinolin-7-yl]-6-nitroisoquinoline-3-carboxamide Show/Hide	C30H30N4O6	2
1	EC50 = 108.1 nM Bioactivity Info	TI LI LO TS
2	Ki = 94.7 nM Bioactivity Info	TI LI LO TS
CP0325247 Compound Info	(2S)-2-amino-N-[(4R,10S,15S,21R)-21-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-10,15-dibenzyl-3,3,22,22-tetramethyl-5,8,11,14,17,20-hexaoxo-1,2-dithia-6,9,12,13,16,19-hexazacyclodocos-4-yl]-3-(4-hydroxyphenyl)propanamide Show/Hide	C50H62N10O10S2	1
1	EC50 = 360 nM Bioactivity Info	TI LI LO TS
CP0050068 Compound Info	(1S,2S,13R,21R)-22-(cyclopropylmethyl)-14-oxa-11,22-diazaheptacyclo[13.9.1.01,13.02,21.04,12.05,10.019,25]pentacosa-4(12),5,7,9,15,17,19(25)-heptaene-2,16-diol Show/Hide	C26H26N2O3	1
1	IC50 = 0.72 nM Bioactivity Info	TI LI LO TS
CP0456600 Compound Info	2-[2-({2-[2-Amino-3-(4-hydroxy-phenyl)-propionyl]-1,2,3,4-tetrahydro-isoquinoline-3-carbonyl}-amino)-3-phenyl-propionylamino]-3-(4-isothiocyanato-phenyl)-propionic acid Show/Hide	C38H37N5O6S	1
1	IC50 = 5.4 nM Bioactivity Info	TI LI LO TS
CP0043354 Compound Info	2-[2-({(S)-2-[2-Amino-3-(4-hydroxy-phenyl)-propionyl]-4-methyl-1,2,3,4-tetrahydro-isoquinoline-3-carbonyl}-amino)-3-phenyl-propionylamino]-3-phenyl-propionic acid Show/Hide	C37H38N4O6	1
1	IC50 = 5.8 nM Bioactivity Info	TI LI LO TS
CP0723478 Compound Info	2-[2-({2-[2-Amino-3-(4-hydroxy-phenyl)-propionyl]-1,2,3,4-tetrahydro-isoquinoline-3-carbonyl}-amino)-3-phenyl-propionylamino]-3-(4-amino-phenyl)-propionic acid Show/Hide	C37H39N5O6	1
1	IC50 = 11.8 nM Bioactivity Info	TI LI LO TS
CP0538351 Compound Info	2-[2-({2-[2-Amino-3-(4-hydroxy-phenyl)-propionyl]-1,2,3,4-tetrahydro-isoquinoline-3-carbonyl}-amino)-3-(4-isothiocyanato-phenyl)-propionylamino]-3-phenyl-propionic acid Show/Hide	C38H37N5O6S	1
1	IC50 = 12.4 nM Bioactivity Info	TI LI LO TS
CP0916467 Compound Info	2-[2-(2-{2-[2-Dibenzylamino-3-(4-hydroxy-phenyl)-propionylamino]-acetylamino}-acetylamino)-3-(4-isothiocyanato-phenyl)-propionylamino]-4-methyl-pentanoic acid Show/Hide	C43H48N6O7S	1
1	IC50 = 34.9 nM Bioactivity Info	TI LI LO TS
CP0430349 Compound Info	methyl (E)-2-[(2S,6'S,7'S,8'aS)-6'-ethyl-4-(furan-3-yl)-3-oxospiro[1H-indole-2,1'-3,5,6,7,8,8a-hexahydro-2H-indolizine]-7'-yl]-3-methoxyprop-2-enoate Show/Hide	C26H30N2O5	2
1	IC50 = 39 nM Bioactivity Info	TI LI LO TS
2	Ki = 1.5 nM Bioactivity Info	TI LI LO TS
CP0086185 Compound Info	methyl (E)-2-[(2S,6'S,7'S,8'aS)-6'-ethyl-4-methoxy-3-oxospiro[1H-indole-2,1'-3,5,6,7,8,8a-hexahydro-2H-indolizine]-7'-yl]-3-methoxyprop-2-enoate Show/Hide	C23H30N2O5	2
1	IC50 = 61 nM Bioactivity Info	TI LI LO TS
2	Ki = 3 nM Bioactivity Info	TI LI LO TS
CP0540668 Compound Info	methyl (E)-2-[(2S,6'S,7'S,8'aS)-4-cyano-6'-ethyl-3-oxospiro[1H-indole-2,1'-3,5,6,7,8,8a-hexahydro-2H-indolizine]-7'-yl]-3-methoxyprop-2-enoate Show/Hide	C23H27N3O4	2
1	IC50 = 73 nM Bioactivity Info	TI LI LO TS
2	Ki = 2.4 nM Bioactivity Info	TI LI LO TS
CP0846695 Compound Info	2-[2-(2-{2-[2-Dibenzylamino-3-(4-hydroxy-phenyl)-propionylamino]-acetylamino}-acetylamino)-3-phenyl-propionylamino]-4-methyl-pentanoic acid Show/Hide	C42H49N5O7	1
1	IC50 = 78.2 nM Bioactivity Info	TI LI LO TS
CP0786258 Compound Info	2-[2-({2-[2-Amino-3-(4-hydroxy-phenyl)-propionyl]-1,2,3,4-tetrahydro-isoquinoline-3-carbonyl}-amino)-3-(4-amino-phenyl)-propionylamino]-3-phenyl-propionic acid Show/Hide	C37H39N5O6	1
1	IC50 = 87.7 nM Bioactivity Info	TI LI LO TS
CP0895837 Compound Info	2-[3-[4-(Chloromethyl-amino)-phenyl]-2-(2-{2-[2-dibenzylamino-3-(4-hydroxy-phenyl)-propionylamino]-acetylamino}-acetylamino)-propionylamino]-4-methyl-pentanoic acid Show/Hide	C43H51ClN6O7	1
1	IC50 = 145 nM Bioactivity Info	TI LI LO TS
CP0448264 Compound Info	2-[3-[4-(2-Bromo-acetylamino)-phenyl]-2-(2-{2-[2-dibenzylamino-3-(4-hydroxy-phenyl)-propionylamino]-acetylamino}-acetylamino)-propionylamino]-4-methyl-pentanoic acid Show/Hide	C44H51BrN6O8	1
1	IC50 = 149 nM Bioactivity Info	TI LI LO TS
CP0430356 Compound Info	methyl (E)-2-[(2S,6'S,7'S,8'aS)-6'-ethyl-3-oxospiro[1H-indole-2,1'-3,5,6,7,8,8a-hexahydro-2H-indolizine]-7'-yl]-3-methoxyprop-2-enoate Show/Hide	C22H28N2O4	2
1	IC50 = 193 nM Bioactivity Info	TI LI LO TS
2	Ki = 2.9 nM Bioactivity Info	TI LI LO TS
CP0451265 Compound Info	methyl (E)-2-[(2S,6'S,7'S,8'aS)-6'-ethyl-4-hydroxy-3-oxospiro[1H-indole-2,1'-3,5,6,7,8,8a-hexahydro-2H-indolizine]-7'-yl]-3-methoxyprop-2-enoate Show/Hide	C22H28N2O5	2
1	IC50 = 293 nM Bioactivity Info	TI LI LO TS
2	Ki = 6.1 nM Bioactivity Info	TI LI LO TS
CP0866750 Compound Info	2-[2-(2-{2-[2-Diallylamino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-propionylamino)-3-(4-isothiocyanato-phenyl)-propionylamino]-4-methyl-pentanoic acid Show/Hide	C37H48N6O7S	1
1	IC50 = 361 nM Bioactivity Info	TI LI LO TS
CP0845390 Compound Info	2-[3-[4-(2-Bromo-acetylamino)-phenyl]-2-(2-{2-[2-diallylamino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-propionylamino)-propionylamino]-4-methyl-pentanoic acid Show/Hide	C38H51BrN6O8	1
1	IC50 = 392 nM Bioactivity Info	TI LI LO TS
CP0866945 Compound Info	2-[3-(4-Amino-phenyl)-2-(2-{2-[2-dibenzylamino-3-(4-hydroxy-phenyl)-propionylamino]-acetylamino}-acetylamino)-propionylamino]-4-methyl-pentanoic acid Show/Hide	C42H50N6O7	1
1	IC50 = 486 nM Bioactivity Info	TI LI LO TS
CP0055167 Compound Info	methyl (E)-2-[(2S,3S,7aS,12bS)-3-ethyl-7a-hydroxy-8-methoxy-2,3,4,6,7,12b-hexahydro-1H-indolo[2,3-a]quinolizin-2-yl]-3-methoxyprop-2-enoate Show/Hide	C23H30N2O5	2
1	IC50 = 691 nM Bioactivity Info	TI LI LO TS
2	Ki = 90 nM Bioactivity Info	TI LI LO TS
CP0053097 Compound Info	2-[2-(2-{2-[2-Diallylamino-3-(4-hydroxy-phenyl)-propionylamino]-2-methyl-propionylamino}-2-methyl-propionylamino)-3-phenyl-propionylamino]-4-methyl-pentanoic acid Show/Hide	C38H53N5O7	1
1	IC50 = 703 nM Bioactivity Info	TI LI LO TS
CP0955372 Compound Info	2-[3-(4-Amino-phenyl)-2-(2-{2-[2-diallylamino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-propionylamino)-propionylamino]-4-methyl-pentanoic acid Show/Hide	C37H52N6O7	1
1	IC50 = 1394 nM Bioactivity Info	TI LI LO TS
CP0135923 Compound Info	CHEBI:6956 Show/Hide	C23H30N2O4	2
1	IC50 > 4000 nM Bioactivity Info	TI LI LO TS
2	Ki = 1011 nM Bioactivity Info	TI LI LO TS
CP0381721 Compound Info	N-[(4R,4aS,7R,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-dihydroxy-1,2,4,5,6,7,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinolin-7-yl]-3-iodobenzamide Show/Hide	C27H29IN2O4	1
1	Ki = 0.24 nM Bioactivity Info	TI LI LO TS
CP0451932 Compound Info	N-[(4R,4aS,7R,7aR,12bS)-4a,9-dihydroxy-3-methyl-1,2,4,5,6,7,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinolin-7-yl]-3-iodobenzamide Show/Hide	C24H25IN2O4	1
1	Ki = 2.45 nM Bioactivity Info	TI LI LO TS
CP0448209 Compound Info	N-[(4R,4aS,7R,7aR,12bS)-4a,9-dihydroxy-3-prop-2-enyl-1,2,4,5,6,7,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinolin-7-yl]-3-iodobenzamide Show/Hide	C26H27IN2O4	1
1	Ki = 2.55 nM Bioactivity Info	TI LI LO TS
CP0369775 Compound Info	ETORPHINE Show/Hide	C25H33NO4	1
1	Ki = 2.9 nM Bioactivity Info	TI LI LO TS
CP0376790 Compound Info	N-[(4R,4aS,7R,7aR,12bS)-4a,9-dihydroxy-3-prop-2-enyl-1,2,4,5,6,7,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinolin-7-yl]-3-(trifluoromethyl)benzamide Show/Hide	C27H27F3N2O4	1
1	Ki = 2.96 nM Bioactivity Info	TI LI LO TS
CP0406962 Compound Info	(3R,6R,12R)-N-[(2S)-1-[[(2S)-1-[[(2S,3S)-1-[[(2S)-1-[(2S)-2-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1,6-diamino-1-oxohexan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]pyrrolidin-1-yl]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]-12-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-6-benzyl-5,8,11,14-tetraoxo-1,4,7,10-tetrazacyclotetradecane-3-carboxamide Show/Hide	C74H122N26O15	1
1	Ki = 3.31 nM Bioactivity Info	TI LI LO TS
CP0525477 Compound Info	N-[(4R,4aS,7R,7aR,12bS)-4a,9-dihydroxy-3-prop-2-enyl-1,2,4,5,6,7,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinolin-7-yl]-4-iodobenzamide Show/Hide	C26H27IN2O4	1
1	Ki = 3.36 nM Bioactivity Info	TI LI LO TS
CP0460731 Compound Info	(3R)-4-[[2-[[(2S)-1-[[(2S)-3-amino-1-[[(2S)-1-[[(2S)-1-[[(2S,3S)-1-[[(2S)-1-[(2S)-2-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1,6-diamino-1-oxohexan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]pyrrolidin-1-yl]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-2-oxoethyl]amino]-3-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-4-oxobutanoic acid Show/Hide	C74H124N26O16	1
1	Ki = 3.9 nM Bioactivity Info	TI LI LO TS
CP0379250 Compound Info	N-[(4R,4aS,7S,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-dihydroxy-1,2,4,5,6,7,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinolin-7-yl]-7-(dimethylamino)-2-methyl-3,4-dihydro-1H-isoquinoline-3-carboxamide Show/Hide	C33H42N4O4	1
1	Ki = 4.5 nM Bioactivity Info	TI LI LO TS
CP0376795 Compound Info	N-[(4R,4aS,7R,7aR,12bS)-4a,9-dihydroxy-3-prop-2-enyl-1,2,4,5,6,7,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinolin-7-yl]-3-chlorobenzamide Show/Hide	C26H27ClN2O4	1
1	Ki = 4.87 nM Bioactivity Info	TI LI LO TS
CP0448454 Compound Info	(3R,6R,12R)-12-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-6-benzyl-N-[(2S)-5-(diaminomethylideneamino)-1-[[(2S)-5-(diaminomethylideneamino)-1-[[(2S,3S)-1-[[(2S)-5-(diaminomethylideneamino)-1-[(2S)-2-[[(2S)-1,6-diamino-1-oxohexan-2-yl]carbamoyl]pyrrolidin-1-yl]-1-oxopentan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-1-oxopentan-2-yl]amino]-1-oxopentan-2-yl]-5,8,11,14-tetraoxo-1,4,7,10-tetrazacyclotetradecane-3-carboxamide Show/Hide	C62H99N23O13	1
1	Ki = 5.1 nM Bioactivity Info	TI LI LO TS
CP0462179 Compound Info	(E)-N-[(4R,4aR,7R,7aR,12bS)-9-hydroxy-3-methyl-2,4,4a,7,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7-yl]-3-(3-nitrophenyl)prop-2-enamide Show/Hide	C26H25N3O5	1
1	Ki = 5.15 nM Bioactivity Info	TI LI LO TS
CP0381718 Compound Info	N-[(4R,4aS,7R,7aR,12bS)-4a,9-dihydroxy-3-prop-2-enyl-1,2,4,5,6,7,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinolin-7-yl]naphthalene-2-carboxamide Show/Hide	C30H30N2O4	1
1	Ki = 5.51 nM Bioactivity Info	TI LI LO TS
CP0293493 Compound Info	(2S)-N-[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1,6-diamino-1-oxohexan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-1-oxohexan-2-yl]-1-[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-3-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]pyrrolidine-2-carboxamide Show/Hide	C75H127N25O14	1
1	Ki = 6.07 nM Bioactivity Info	TI LI LO TS
CP0047082 Compound Info	(2S)-1-[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-3-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]-N-[(2S)-1,6-diamino-1-oxohexan-2-yl]pyrrolidine-2-carboxamide Show/Hide	C63H104N22O12	1
1	Ki = 6.18 nM Bioactivity Info	TI LI LO TS
CP0440935 Compound Info	(2S)-1-[(2S)-2-[[(2R)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2R)-2-[[2-[[2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]propanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]-N-[(2S)-1,6-diamino-1-oxohexan-2-yl]pyrrolidine-2-carboxamide Show/Hide	C60H98N22O12	1
1	Ki = 6.57 nM Bioactivity Info	TI LI LO TS
CP0880018 Compound Info	(5S,8S,13R,E)-13-((S)-2-amino-3-(4-hydroxyphenyl)propanamido)-5-benzyl-N-((6S,9S,12S,15S)-1,20-diamino-9-sec-butyl-6-((S)-2-((S)-1,6-diamino-1-oxohexan-2-ylcarbamoyl)pyrrolidine-1-carbonyl)-12-(3-guanidinopropyl)-1,20-diimino-8,11,14-trioxo-2,7,10,13,19-pentaazaicosan-15-yl)-3,6,14-trioxo-1,4,7-triazacyclotetradec-10-ene-8-carboxamide Show/Hide	C63H100N22O12	1
1	Ki = 7.17 nM Bioactivity Info	TI LI LO TS
CP0488780 Compound Info	N-[(4R,4aS,7S,7aR,12bS)-4a,9-dihydroxy-3-prop-2-enyl-1,2,4,5,6,7,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinolin-7-yl]-3-iodobenzamide Show/Hide	C26H27IN2O4	1
1	Ki = 7.64 nM Bioactivity Info	TI LI LO TS
CP0148509 Compound Info	DYNORPHIN A (1-11) Show/Hide	C63H103N21O13	1
1	Ki = 8.18 nM Bioactivity Info	TI LI LO TS
CP0488751 Compound Info	N-[(4R,4aS,7R,7aR,12bS)-4a,9-dihydroxy-3-prop-2-enyl-1,2,4,5,6,7,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinolin-7-yl]-3-methylbenzamide Show/Hide	C27H30N2O4	1
1	Ki = 8.24 nM Bioactivity Info	TI LI LO TS
CP0379323 Compound Info	N-[(4R,4aS,7S,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-dihydroxy-1,2,4,5,6,7,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinolin-7-yl]-3-isoquinolin-3-ylpropanamide Show/Hide	C32H35N3O4	1
1	Ki = 8.4 nM Bioactivity Info	TI LI LO TS
CP0376008 Compound Info	N-[2-[[(4R,4aS,7S,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-dihydroxy-1,2,4,5,6,7,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinolin-7-yl]amino]-2-oxoethyl]isoquinoline-3-carboxamide Show/Hide	C32H34N4O5	1
1	Ki = 9.2 nM Bioactivity Info	TI LI LO TS
CP0859808 Compound Info	(5S,8S,13R,Z)-13-((S)-2-amino-3-(4-hydroxyphenyl)propanamido)-5-benzyl-N-((6S,9S,12S,15S)-1,20-diamino-9-sec-butyl-6-((S)-2-((S)-1,6-diamino-1-oxohexan-2-ylcarbamoyl)pyrrolidine-1-carbonyl)-12-(3-guanidinopropyl)-1,20-diimino-8,11,14-trioxo-2,7,10,13,19-pentaazaicosan-15-yl)-3,6,14-trioxo-1,4,7-triazacyclotetradec-10-ene-8-carboxamide Show/Hide	C63H100N22O12	1
1	Ki = 9.3 nM Bioactivity Info	TI LI LO TS
CP0379324 Compound Info	(3S)-N-[(4R,4aS,7S,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-dihydroxy-1,2,4,5,6,7,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinolin-7-yl]-2-methyl-3,4-dihydro-1H-isoquinoline-3-carboxamide Show/Hide	C31H37N3O4	1
1	Ki = 9.3 nM Bioactivity Info	TI LI LO TS
CP0411622 Compound Info	(E)-N-[(4R,4aR,7R,7aR,12bS)-9-hydroxy-3-methyl-2,4,4a,7,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7-yl]-3-(4-chlorophenyl)prop-2-enamide Show/Hide	C26H25ClN2O3	1
1	Ki = 9.38 nM Bioactivity Info	TI LI LO TS
CP0517634 Compound Info	N-[(4R,4aS,7R,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-dihydroxy-1,2,4,5,6,7,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinolin-7-yl]-3-cyclohexylpyridine-4-carboxamide Show/Hide	C32H39N3O4	1
1	Ki = 11.24 nM Bioactivity Info	TI LI LO TS
CP0514011 Compound Info	N-[(4R,4aS,7R,7aR,12bS)-4a,9-dihydroxy-3-prop-2-enyl-1,2,4,5,6,7,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinolin-7-yl]-3-hydroxybenzamide Show/Hide	C26H28N2O5	1
1	Ki = 11.25 nM Bioactivity Info	TI LI LO TS
CP0440275 Compound Info	(3R)-4-[[2-[[(2S)-1-[[(2S)-3-amino-1-[[(2S)-5-(diaminomethylideneamino)-1-[[(2S)-5-(diaminomethylideneamino)-1-[[(2S,3S)-1-[[(2S)-5-(diaminomethylideneamino)-1-[(2S)-2-[[(2S)-1,6-diamino-1-oxohexan-2-yl]carbamoyl]pyrrolidin-1-yl]-1-oxopentan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-1-oxopentan-2-yl]amino]-1-oxopentan-2-yl]amino]-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-2-oxoethyl]amino]-3-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-4-oxobutanoic acid Show/Hide	C62H101N23O14	1
1	Ki = 11.6 nM Bioactivity Info	TI LI LO TS
CP0375589 Compound Info	N-[(4R,4aS,7S,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-dihydroxy-1,2,4,5,6,7,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinolin-7-yl]-2-isoquinolin-3-ylacetamide Show/Hide	C31H33N3O4	1
1	Ki = 12.5 nM Bioactivity Info	TI LI LO TS
CP0438132 Compound Info	N-[(4R,4aS,7S,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-dihydroxy-1,2,4,5,6,7,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinolin-7-yl]-1H-indole-7-carboxamide;hydrochloride Show/Hide	C29H32ClN3O4	1
1	Ki = 13.69 nM Bioactivity Info	TI LI LO TS
CP0411620 Compound Info	(E)-N-[(4R,4aR,7R,7aR,12bS)-9-hydroxy-3-methyl-2,4,4a,7,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7-yl]-3-[4-(trifluoromethyl)phenyl]prop-2-enamide Show/Hide	C27H25F3N2O3	1
1	Ki = 14.52 nM Bioactivity Info	TI LI LO TS
CP0401958 Compound Info	N-[(4R,4aS,7R,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-dihydroxy-1,2,4,5,6,7,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinolin-7-yl]-3-cycloheptylpyridine-4-carboxamide Show/Hide	C33H41N3O4	1
1	Ki = 14.97 nM Bioactivity Info	TI LI LO TS
CP0488783 Compound Info	N-[(4R,4aS,7R,7aR,12bS)-4a,9-dihydroxy-3-prop-2-enyl-1,2,4,5,6,7,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinolin-7-yl]tridecanamide Show/Hide	C32H48N2O4	1
1	Ki = 15.25 nM Bioactivity Info	TI LI LO TS
CP0508806 Compound Info	(E)-N-[(4R,4aR,7R,7aR,12bS)-9-hydroxy-3-methyl-2,4,4a,7,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7-yl]-3-(4-methoxyphenyl)prop-2-enamide Show/Hide	C27H28N2O4	1
1	Ki = 15.26 nM Bioactivity Info	TI LI LO TS
CP0376739 Compound Info	N-[(4R,4aS,7R,7aR,12bS)-4a,9-dihydroxy-3-prop-2-enyl-1,2,4,5,6,7,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinolin-7-yl]-3-methoxybenzamide Show/Hide	C27H30N2O5	1
1	Ki = 17.22 nM Bioactivity Info	TI LI LO TS
CP0451842 Compound Info	N-[(4R,4aS,7S,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-dihydroxy-1,2,4,5,6,7,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinolin-7-yl]-1-chloro-4-hydroxyisoquinoline-3-carboxamide Show/Hide	C30H30ClN3O5	1
1	Ki = 17.4 nM Bioactivity Info	TI LI LO TS
CP0488795 Compound Info	N-[(4R,4aS,7R,7aR,12bS)-4a,9-dihydroxy-3-prop-2-enyl-1,2,4,5,6,7,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinolin-7-yl]-4-(trifluoromethoxy)benzamide Show/Hide	C27H27F3N2O5	1
1	Ki = 17.88 nM Bioactivity Info	TI LI LO TS
CP0477031 Compound Info	N-[(4R,4aS,7R,7aR,12bS)-4a,9-dihydroxy-3-prop-2-enyl-1,2,4,5,6,7,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinolin-7-yl]-3-nitrobenzamide Show/Hide	C26H27N3O6	1
1	Ki = 18.13 nM Bioactivity Info	TI LI LO TS
CP0488787 Compound Info	N-[(4R,4aS,7R,7aR,12bS)-4a,9-dihydroxy-3-prop-2-enyl-1,2,4,5,6,7,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinolin-7-yl]-3-fluorobenzamide Show/Hide	C26H27FN2O4	1
1	Ki = 18.19 nM Bioactivity Info	TI LI LO TS
CP0448208 Compound Info	N-[(4R,4aS,7R,7aR,12bS)-4a,9-dihydroxy-3-prop-2-enyl-1,2,4,5,6,7,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinolin-7-yl]-4-phenylbenzamide Show/Hide	C32H32N2O4	1
1	Ki = 19.15 nM Bioactivity Info	TI LI LO TS
CP0430355 Compound Info	methyl (E)-2-[(2S,6'S,7'S,8'aS)-4-acetyloxy-6'-ethyl-3-oxospiro[1H-indole-2,1'-3,5,6,7,8,8a-hexahydro-2H-indolizine]-7'-yl]-3-methoxyprop-2-enoate Show/Hide	C24H30N2O6	1
1	Ki = 20 nM Bioactivity Info	TI LI LO TS
CP0376738 Compound Info	N-[(4R,4aS,7R,7aR,12bS)-4a,9-dihydroxy-3-prop-2-enyl-1,2,4,5,6,7,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinolin-7-yl]-2-iodobenzamide Show/Hide	C26H27IN2O4	1
1	Ki = 22.8 nM Bioactivity Info	TI LI LO TS
CP0389222 Compound Info	(2S)-1-[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]propanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-3-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]-N-[(2S)-1,6-diamino-1-oxohexan-2-yl]pyrrolidine-2-carboxamide Show/Hide	C64H106N22O12	1
1	Ki = 23.3 nM Bioactivity Info	TI LI LO TS
CP0488797 Compound Info	N-[(4R,4aS,7R,7aR,12bS)-4a,9-dihydroxy-3-prop-2-enyl-1,2,4,5,6,7,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinolin-7-yl]-3-bromobenzamide Show/Hide	C26H27BrN2O4	1
1	Ki = 23.37 nM Bioactivity Info	TI LI LO TS
CP0511642 Compound Info	(3R,6R,9S,12R)-12-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-6-benzyl-N-[(2S)-5-(diaminomethylideneamino)-1-[[(2S)-5-(diaminomethylideneamino)-1-[[(2S,3S)-1-[[(2S)-5-(diaminomethylideneamino)-1-[(2S)-2-[[(2S)-1,6-diamino-1-oxohexan-2-yl]carbamoyl]pyrrolidin-1-yl]-1-oxopentan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-1-oxopentan-2-yl]amino]-1-oxopentan-2-yl]-9-methyl-5,8,11,14-tetraoxo-1,4,7,10-tetrazacyclotetradecane-3-carboxamide Show/Hide	C63H101N23O13	1
1	Ki = 30.8 nM Bioactivity Info	TI LI LO TS
CP0376737 Compound Info	N-[(4R,4aS,7R,7aR,12bS)-4a,9-dihydroxy-3-prop-2-enyl-1,2,4,5,6,7,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinolin-7-yl]heptanamide Show/Hide	C26H36N2O4	1
1	Ki = 32.2 nM Bioactivity Info	TI LI LO TS
CP0376007 Compound Info	N-[(4R,4aS,7S,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-dihydroxy-1,2,4,5,6,7,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinolin-7-yl]-4-hydroxyisoquinoline-3-carboxamide Show/Hide	C30H31N3O5	1
1	Ki = 32.8 nM Bioactivity Info	TI LI LO TS
CP0477127 Compound Info	N-[(4R,4aS,7R,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-dihydroxy-1,2,4,5,6,7,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinolin-7-yl]-3-cyclopentylpyridine-4-carboxamide Show/Hide	C31H37N3O4	1
1	Ki = 33.99 nM Bioactivity Info	TI LI LO TS
CP0923260 Compound Info	N-(6-dezoxymorphine-6beta-yl)nicotinamide Show/Hide	C23H23N3O3	1
1	Ki = 34.4 nM Bioactivity Info	TI LI LO TS
CP0376797 Compound Info	N-[(4R,4aS,7R,7aR,12bS)-4a,9-dihydroxy-3-prop-2-enyl-1,2,4,5,6,7,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinolin-7-yl]-3-aminobenzamide Show/Hide	C26H29N3O4	1
1	Ki = 36 nM Bioactivity Info	TI LI LO TS
CP0468971 Compound Info	N-[(4R,4aS,7R,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-dihydroxy-1,2,4,5,6,7,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinolin-7-yl]-3-ethylpyridine-4-carboxamide Show/Hide	C28H33N3O4	1
1	Ki = 42.86 nM Bioactivity Info	TI LI LO TS
CP0468970 Compound Info	N-[(4R,4aS,7R,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-dihydroxy-1,2,4,5,6,7,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinolin-7-yl]-3-phenylpyridine-4-carboxamide Show/Hide	C32H33N3O4	1
1	Ki = 44.83 nM Bioactivity Info	TI LI LO TS
CP0401954 Compound Info	N-[(4R,4aS,7R,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-dihydroxy-1,2,4,5,6,7,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinolin-7-yl]-3-cyanopyridine-4-carboxamide Show/Hide	C27H28N4O4	1
1	Ki = 46.29 nM Bioactivity Info	TI LI LO TS
CP0488752 Compound Info	N-[(4R,4aS,7R,7aR,12bS)-4a,9-dihydroxy-3-prop-2-enyl-1,2,4,5,6,7,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinolin-7-yl]-3-(dimethylamino)benzamide Show/Hide	C28H33N3O4	1
1	Ki = 51.35 nM Bioactivity Info	TI LI LO TS
CP0488976 Compound Info	(3R)-4-[[(2S)-1-[[(2S)-1-[[(2S)-3-amino-1-[[(2S)-5-(diaminomethylideneamino)-1-[[(2S)-5-(diaminomethylideneamino)-1-[[(2S,3S)-1-[[(2S)-5-(diaminomethylideneamino)-1-[(2S)-2-[[(2S)-1,6-diamino-1-oxohexan-2-yl]carbamoyl]pyrrolidin-1-yl]-1-oxopentan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-1-oxopentan-2-yl]amino]-1-oxopentan-2-yl]amino]-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-1-oxopropan-2-yl]amino]-3-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-4-oxobutanoic acid Show/Hide	C63H103N23O14	1
1	Ki = 55.1 nM Bioactivity Info	TI LI LO TS
CP0388839 Compound Info	N-[(4R,4aS,7S,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-dihydroxy-1,2,4,5,6,7,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinolin-7-yl]-7-nitroisoquinoline-3-carboxamide Show/Hide	C30H30N4O6	1
1	Ki = 55.3 nM Bioactivity Info	TI LI LO TS
CP0401955 Compound Info	4-[[(4R,4aS,7R,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-dihydroxy-1,2,4,5,6,7,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinolin-7-yl]carbamoyl]pyridine-3-carboxylic acid Show/Hide	C27H29N3O6	1
1	Ki = 55.58 nM Bioactivity Info	TI LI LO TS
CP0438950 Compound Info	(2S)-1-[(2S)-2-[[(2R)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2R)-2-[[2-[[2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]acetyl]-methylamino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]propanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]-N-[(2S)-1,6-diamino-1-oxohexan-2-yl]pyrrolidine-2-carboxamide Show/Hide	C61H100N22O12	1
1	Ki = 56.1 nM Bioactivity Info	TI LI LO TS
CP0455711 Compound Info	N-[(4R,4aS,7R,7aR,12bS)-4a,9-dihydroxy-3-prop-2-enyl-1,2,4,5,6,7,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinolin-7-yl]benzamide Show/Hide	C26H28N2O4	1
1	Ki = 60.78 nM Bioactivity Info	TI LI LO TS
CP0401956 Compound Info	N-[(4R,4aS,7R,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-dihydroxy-1,2,4,5,6,7,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinolin-7-yl]-3-(trifluoromethyl)pyridine-4-carboxamide Show/Hide	C27H28F3N3O4	1
1	Ki = 61.79 nM Bioactivity Info	TI LI LO TS
CP0849956 Compound Info	N-(6-dezoxymorphine-6beta-yl)isonicotinamide Show/Hide	C23H23N3O3	1
1	Ki = 65 nM Bioactivity Info	TI LI LO TS
CP0379249 Compound Info	N-[(4R,4aS,7S,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-dihydroxy-1,2,4,5,6,7,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinolin-7-yl]-7-(dimethylamino)isoquinoline-3-carboxamide Show/Hide	C32H36N4O4	1
1	Ki = 68.6 nM Bioactivity Info	TI LI LO TS
CP0398303 Compound Info	N-[(4R,4aS,7S,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-dihydroxy-1,2,4,5,6,7,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinolin-7-yl]-6,7-dimethoxyisoquinoline-3-carboxamide Show/Hide	C32H35N3O6	1
1	Ki = 69.2 nM Bioactivity Info	TI LI LO TS
CP0375588 Compound Info	N-[(4R,4aS,7S,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-dihydroxy-1,2,4,5,6,7,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinolin-7-yl]quinazoline-2-carboxamide Show/Hide	C29H30N4O4	1
1	Ki = 78.8 nM Bioactivity Info	TI LI LO TS
CP0397511 Compound Info	N-[(4R,4aS,7S,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-dihydroxy-1,2,4,5,6,7,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinolin-7-yl]-1-chloroisoquinoline-3-carboxamide Show/Hide	C30H30ClN3O4	1
1	Ki = 79.8 nM Bioactivity Info	TI LI LO TS
CP0401959 Compound Info	N-[(4R,4aS,7R,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-dihydroxy-1,2,4,5,6,7,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinolin-7-yl]-3-nitropyridine-4-carboxamide Show/Hide	C26H28N4O6	1
1	Ki = 95.61 nM Bioactivity Info	TI LI LO TS
CP0926696 Compound Info	N-(6-dezoxy-14alpha-hydroxy-7,8-dihydromorphine-6beta-yl)nicotinamide Show/Hide	C23H25N3O4	1
1	Ki = 103.7 nM Bioactivity Info	TI LI LO TS
CP0375587 Compound Info	N-[(4R,4aS,7S,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-dihydroxy-1,2,4,5,6,7,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinolin-7-yl]-1-methylisoquinoline-3-carboxamide Show/Hide	C31H33N3O4	1
1	Ki = 117.5 nM Bioactivity Info	TI LI LO TS
CP0401520 Compound Info	(2R)-1-[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[2-[[(2S)-2-(benzylamino)-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]-methylamino]-5-(diaminomethylideneamino)pentanoyl]amino]-3-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]-N-[(2S)-1,6-diamino-1-oxohexan-2-yl]pyrrolidine-2-carboxamide Show/Hide	C71H112N22O12	1
1	Ki = 120 nM Bioactivity Info	TI LI LO TS
CP0386572 Compound Info	N-[(4R,4aS,7S,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-dihydroxy-1,2,4,5,6,7,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinolin-7-yl]-1-cyanoisoquinoline-3-carboxamide Show/Hide	C31H30N4O4	1
1	Ki = 129.9 nM Bioactivity Info	TI LI LO TS
CP0865241 Compound Info	N-(6-dezoxy-7,8-dihydromorphine-6beta-yl)nicotinamide Show/Hide	C23H25N3O3	1
1	Ki = 130.3 nM Bioactivity Info	TI LI LO TS
CP0401960 Compound Info	methyl 4-[[(4R,4aS,7R,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-dihydroxy-1,2,4,5,6,7,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinolin-7-yl]carbamoyl]pyridine-3-carboxylate Show/Hide	C28H31N3O6	1
1	Ki = 137.31 nM Bioactivity Info	TI LI LO TS
CP0407002 Compound Info	(3R,6R,9R,12R)-12-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-6-benzyl-N-[(2S)-5-(diaminomethylideneamino)-1-[[(2S)-5-(diaminomethylideneamino)-1-[[(2S,3S)-1-[[(2S)-5-(diaminomethylideneamino)-1-[(2S)-2-[[(2S)-1,6-diamino-1-oxohexan-2-yl]carbamoyl]pyrrolidin-1-yl]-1-oxopentan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-1-oxopentan-2-yl]amino]-1-oxopentan-2-yl]-9-methyl-5,8,11,14-tetraoxo-1,4,7,10-tetrazacyclotetradecane-3-carboxamide Show/Hide	C63H101N23O13	1
1	Ki = 139 nM Bioactivity Info	TI LI LO TS
CP0401521 Compound Info	(2R)-1-[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[2-[[(2S)-2-(benzylamino)-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-3-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]-N-[(2S)-1,6-diamino-1-oxohexan-2-yl]pyrrolidine-2-carboxamide Show/Hide	C70H110N22O12	1
1	Ki = 148 nM Bioactivity Info	TI LI LO TS
CP0401957 Compound Info	N-[(4R,4aS,7R,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-dihydroxy-1,2,4,5,6,7,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinolin-7-yl]-3-(2-methylpropyl)pyridine-4-carboxamide Show/Hide	C30H37N3O4	1
1	Ki = 148.75 nM Bioactivity Info	TI LI LO TS
CP0477362 Compound Info	N-[(4R,4aS,7R,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-dihydroxy-1,2,4,5,6,7,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinolin-7-yl]-3-fluoropyridine-4-carboxamide Show/Hide	C26H28FN3O4	1
1	Ki = 156.93 nM Bioactivity Info	TI LI LO TS
CP0382377 Compound Info	(2S)-1-[(2S)-2-[[(2R)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2R)-2-[[2-[[2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]acetyl]amino]-2-methyl-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]propanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]-N-[(2S)-1,6-diamino-1-oxohexan-2-yl]pyrrolidine-2-carboxamide Show/Hide	C61H100N22O12	1
1	Ki = 157 nM Bioactivity Info	TI LI LO TS
CP0407043 Compound Info	(2S)-1-[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-3-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]-N-[(2S)-1,6-diamino-1-oxohexan-2-yl]pyrrolidine-2-carboxamide Show/Hide	C72H111N23O12	1
1	Ki = 168 nM Bioactivity Info	TI LI LO TS
CP0926695 Compound Info	N-(6-dezoxy-14alpha-hydroxy-7,8-dihydromorphine-6beta-yl)isonicotinamide Show/Hide	C23H25N3O4	1
1	Ki = 173.4 nM Bioactivity Info	TI LI LO TS
CP0463519 Compound Info	(2S)-1-[(2S)-2-[[(2R)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2R)-2-[[2-[[2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]acetyl]amino]-4-phenylbutanoyl]amino]-4-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]propanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]-N-[(2S)-1,6-diamino-1-oxohexan-2-yl]pyrrolidine-2-carboxamide Show/Hide	C61H100N22O12	1
1	Ki = 190 nM Bioactivity Info	TI LI LO TS
CP0849955 Compound Info	N-(6-dezoxy-7,8-dihydromorphine-6beta-yl)isonicotinamide Show/Hide	C23H25N3O3	1
1	Ki = 198.4 nM Bioactivity Info	TI LI LO TS
CP0445422 Compound Info	(2S)-1-[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2R)-2-[[2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]propanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-3-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]-N-[(2S)-1,6-diamino-1-oxohexan-2-yl]pyrrolidine-2-carboxamide Show/Hide	C64H106N22O12	1
1	Ki = 213 nM Bioactivity Info	TI LI LO TS
CP0495212 Compound Info	methyl (E)-2-[(1S,6S,7S,8aS)-1'-benzyl-6-ethyl-4'-methoxy-3'-oxospiro[3,5,6,7,8,8a-hexahydro-2H-indolizine-1,2'-indole]-7-yl]-3-methoxyprop-2-enoate Show/Hide	C30H36N2O5	1
1	Ki = 258 nM Bioactivity Info	TI LI LO TS
CP0401518 Compound Info	(2R)-1-[(2S)-2-[[(2R)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[2-[[(2S)-2-(benzylamino)-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]propanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]-N-[(2S)-1,6-diamino-1-oxohexan-2-yl]pyrrolidine-2-carboxamide Show/Hide	C67H104N22O12	1
1	Ki = 337 nM Bioactivity Info	TI LI LO TS
CP0310470 Compound Info	(2S)-6-amino-2-[[(2S)-1-[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[2-[[(2S)-2-(benzylamino)-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-3-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]pyrrolidine-2-carbonyl]amino]hexanoic acid Show/Hide	C70H109N21O13	1
1	Ki = 345 nM Bioactivity Info	TI LI LO TS
CP0498441 Compound Info	(2S)-1-[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[2-[[(2S)-2-(benzylamino)-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]-methylamino]-5-(diaminomethylideneamino)pentanoyl]amino]-3-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]-N-[(2S)-1,6-diamino-1-oxohexan-2-yl]pyrrolidine-2-carboxamide Show/Hide	C71H112N22O12	1
1	Ki = 345 nM Bioactivity Info	TI LI LO TS
CP0439122 Compound Info	(2S)-1-[(2S)-2-[[(2R)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[2-[[(2S)-2-(benzylamino)-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]propanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]-N-[(2S)-1,6-diamino-1-oxohexan-2-yl]pyrrolidine-2-carboxamide Show/Hide	C67H104N22O12	1
1	Ki = 372 nM Bioactivity Info	TI LI LO TS
CP0923261 Compound Info	N-(6-dezoxy-3-methyl-morphine-6beta-yl)isonicotinamide Show/Hide	C24H25N3O3	1
1	Ki = 423.9 nM Bioactivity Info	TI LI LO TS
CP0491270 Compound Info	(2S)-1-[(2S)-2-[[(2R)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[2-[[(2S)-2-(benzylamino)-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]-methylamino]-5-(diaminomethylideneamino)pentanoyl]amino]propanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]-N-[(2S)-1,6-diamino-1-oxohexan-2-yl]pyrrolidine-2-carboxamide Show/Hide	C68H106N22O12	1
1	Ki = 458 nM Bioactivity Info	TI LI LO TS
CP0860628 Compound Info	(2S,5S,8S,13S,E)-13-((S)-2-(2-(2-((S)-2-amino-3-(4-hydroxyphenyl)propanamido)acetamido)acetamido)-3-phenylpropanamido)-N-((S)-1-((S)-2-((S)-1,6-diamino-1-oxohexan-2-ylcarbamoyl)pyrrolidin-1-yl)-5-guanidino-1-oxopentan-2-yl)-2,5-bis(3-guanidinopropyl)-3,6,14-trioxo-1,4,7-triazacyclotetradec-10-ene-8-carboxamide Show/Hide	C59H92N22O12	1
1	Ki = 460 nM Bioactivity Info	TI LI LO TS
CP0401516 Compound Info	(2S)-1-[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[2-[[(2S)-2-(benzylamino)-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-3-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]-N-[(2S)-1,6-diamino-1-oxohexan-2-yl]pyrrolidine-2-carboxamide Show/Hide	C70H110N22O12	1
1	Ki = 474 nM Bioactivity Info	TI LI LO TS
CP0879737 Compound Info	PhCH2Tyr-Gly-Gly-Phe-Leu-Arg-N-MeArg7-D-Ala8-Arg-D-Pro10-LysNH2 Show/Hide	C68H106N22O12	1
1	Ki = 665 nM Bioactivity Info	TI LI LO TS
CP0463043 Compound Info	(3R)-4-[[(2R)-1-[[(2S)-1-[[(2S)-3-amino-1-[[(2S)-5-(diaminomethylideneamino)-1-[[(2S)-5-(diaminomethylideneamino)-1-[[(2S,3S)-1-[[(2S)-5-(diaminomethylideneamino)-1-[(2S)-2-[[(2S)-1,6-diamino-1-oxohexan-2-yl]carbamoyl]pyrrolidin-1-yl]-1-oxopentan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-1-oxopentan-2-yl]amino]-1-oxopentan-2-yl]amino]-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-3-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-4-oxobutanoic acid Show/Hide	C71H108N24O14	1
1	Ki = 813 nM Bioactivity Info	TI LI LO TS
CP0429067 Compound Info	(3R)-4-[[(2S)-1-[[(2S)-1-[[(2S)-3-amino-1-[[(2S)-5-(diaminomethylideneamino)-1-[[(2S)-5-(diaminomethylideneamino)-1-[[(2S,3S)-1-[[(2S)-5-(diaminomethylideneamino)-1-[(2S)-2-[[(2S)-1,6-diamino-1-oxohexan-2-yl]carbamoyl]pyrrolidin-1-yl]-1-oxopentan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-1-oxopentan-2-yl]amino]-1-oxopentan-2-yl]amino]-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-3-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-4-oxobutanoic acid Show/Hide	C71H108N24O14	1
1	Ki = 927 nM Bioactivity Info	TI LI LO TS
CP0374752 Compound Info	(3R,6R,9R,12R)-12-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-6-benzyl-N-[(2S)-5-(diaminomethylideneamino)-1-[[(2S)-5-(diaminomethylideneamino)-1-[[(2S,3S)-1-[[(2S)-5-(diaminomethylideneamino)-1-[(2S)-2-[[(2S)-1,6-diamino-1-oxohexan-2-yl]carbamoyl]pyrrolidin-1-yl]-1-oxopentan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-1-oxopentan-2-yl]amino]-1-oxopentan-2-yl]-9-(1H-indol-3-ylmethyl)-5,8,11,14-tetraoxo-1,4,7,10-tetrazacyclotetradecane-3-carboxamide Show/Hide	C71H106N24O13	1
1	Ki = 949 nM Bioactivity Info	TI LI LO TS
CP0394572 Compound Info	(3R)-4-[[(2R)-1-[[(2S)-1-[[(2S)-3-amino-1-[[(2S)-5-(diaminomethylideneamino)-1-[[(2S)-5-(diaminomethylideneamino)-1-[[(2S,3S)-1-[[(2S)-5-(diaminomethylideneamino)-1-[(2S)-2-[[(2S)-1,6-diamino-1-oxohexan-2-yl]carbamoyl]pyrrolidin-1-yl]-1-oxopentan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-1-oxopentan-2-yl]amino]-1-oxopentan-2-yl]amino]-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-1-oxopropan-2-yl]amino]-3-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-4-oxobutanoic acid Show/Hide	C63H103N23O14	1
1	Ki = 959 nM Bioactivity Info	TI LI LO TS
CP0501009 Compound Info	(2S)-6-amino-2-[[(2R)-1-[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[2-[[(2S)-2-(benzylamino)-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-3-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]pyrrolidine-2-carbonyl]amino]hexanoic acid Show/Hide	C70H109N21O13	1
1	Ki = 970 nM Bioactivity Info	TI LI LO TS
CP0383359 Compound Info	(2S)-1-[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2R)-2-[[2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-3-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]-N-[(2S)-1,6-diamino-1-oxohexan-2-yl]pyrrolidine-2-carboxamide Show/Hide	C72H111N23O12	1
1	Ki = 1080 nM Bioactivity Info	TI LI LO TS
CP0880017 Compound Info	(5S,8S,13S,E)-13-((S)-2-amino-3-(4-hydroxyphenyl)propanamido)-5-benzyl-N-((6S,9S,12S,15S)-1,20-diamino-9-sec-butyl-6-((S)-2-((S)-1,6-diamino-1-oxohexan-2-ylcarbamoyl)pyrrolidine-1-carbonyl)-12-(3-guanidinopropyl)-1,20-diimino-8,11,14-trioxo-2,7,10,13,19-pentaazaicosan-15-yl)-3,6,14-trioxo-1,4,7-triazacyclotetradec-10-ene-8-carboxamide Show/Hide	C63H100N22O12	1
1	Ki = 1130 nM Bioactivity Info	TI LI LO TS
CP0859806 Compound Info	(2S,5S,8S,13S,Z)-13-((S)-2-(2-(2-((S)-2-amino-3-(4-hydroxyphenyl)propanamido)acetamido)acetamido)-3-phenylpropanamido)-N-((S)-1-((S)-2-((S)-1,6-diamino-1-oxohexan-2-ylcarbamoyl)pyrrolidin-1-yl)-5-guanidino-1-oxopentan-2-yl)-2,5-bis(3-guanidinopropyl)-3,6,14-trioxo-1,4,7-triazacyclotetradec-10-ene-8-carboxamide Show/Hide	C59H92N22O12	1
1	Ki = 1210 nM Bioactivity Info	TI LI LO TS
CP0380061 Compound Info	(3S)-2-[2-[[2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]acetyl]-N-[(2S)-1-[[(2S)-5-(diaminomethylideneamino)-1-[[(2S)-5-(diaminomethylideneamino)-1-[[(2R)-1-[[(2S)-5-(diaminomethylideneamino)-1-[(2S)-2-[[(2S)-1,6-diamino-1-oxohexan-2-yl]carbamoyl]pyrrolidin-1-yl]-1-oxopentan-2-yl]amino]-1-oxopropan-2-yl]amino]-1-oxopentan-2-yl]amino]-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]-3,4-dihydro-1H-isoquinoline-3-carboxamide Show/Hide	C61H98N22O12	1
1	Ki = 3590 nM Bioactivity Info	TI LI LO TS
CP0439123 Compound Info	(2S)-1-[(3S,6S,9S,12S)-12-[[(2S)-2-[[(2S)-2-[[2-[[2-[[(2S)-2-(benzylamino)-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]-6-[(2S)-butan-2-yl]-9-[3-(diaminomethylideneamino)propyl]-5,8,11,14-tetraoxo-1,4,7,10-tetrazacyclotetradecane-3-carbonyl]-N-[(2S)-1,6-diamino-1-oxohexan-2-yl]pyrrolidine-2-carboxamide Show/Hide	C65H95N17O13	1
1	Ki = 3660 nM Bioactivity Info	TI LI LO TS
CP0401517 Compound Info	(2S)-N-[(2S)-1-[[(2S,3S)-1-[[(2S)-3-acetamido-1-[(2S)-2-[[(2S)-1,6-diamino-1-oxohexan-2-yl]carbamoyl]pyrrolidin-1-yl]-1-oxopropan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]-2-[[(2R)-2-[[(2S)-2-[[2-[[2-[[(2S)-2-(benzylamino)-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]butanediamide Show/Hide	C67H100N18O14	1
1	Ki = 4640 nM Bioactivity Info	TI LI LO TS
CP0418861 Compound Info	(2S)-1-[(2S)-2-[[(2R)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]acetyl]amino]-4-phenylbutanoyl]amino]-4-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]propanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]-N-[(2S)-1,6-diamino-1-oxohexan-2-yl]pyrrolidine-2-carboxamide Show/Hide	C61H100N22O12	1
1	Ki = 5570 nM Bioactivity Info	TI LI LO TS
CP0463642 Compound Info	(3R,6R,9S,12R)-12-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-6-benzyl-N-[(2S)-5-(diaminomethylideneamino)-1-[[(2S)-5-(diaminomethylideneamino)-1-[[(2S,3S)-1-[[(2S)-5-(diaminomethylideneamino)-1-[(2S)-2-[[(2S)-1,6-diamino-1-oxohexan-2-yl]carbamoyl]pyrrolidin-1-yl]-1-oxopentan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-1-oxopentan-2-yl]amino]-1-oxopentan-2-yl]-9-(1H-indol-3-ylmethyl)-5,8,11,14-tetraoxo-1,4,7,10-tetrazacyclotetradecane-3-carboxamide Show/Hide	C71H106N24O13	1
1	Ki = 7070 nM Bioactivity Info	TI LI LO TS
CP0859807 Compound Info	(5S,8S,13S,Z)-13-((S)-2-amino-3-(4-hydroxyphenyl)propanamido)-5-benzyl-N-((6S,9S,12S,15S)-1,20-diamino-9-sec-butyl-6-((S)-2-((S)-1,6-diamino-1-oxohexan-2-ylcarbamoyl)pyrrolidine-1-carbonyl)-12-(3-guanidinopropyl)-1,20-diimino-8,11,14-trioxo-2,7,10,13,19-pentaazaicosan-15-yl)-3,6,14-trioxo-1,4,7-triazacyclotetradec-10-ene-8-carboxamide Show/Hide	C63H100N22O12	1
1	Ki = 7670 nM Bioactivity Info	TI LI LO TS
CP0182171 Compound Info	(2S)-1-[(2S)-2-[[(2R)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]propanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]-N-[(2S)-1,6-diamino-1-oxohexan-2-yl]pyrrolidine-2-carboxamide Show/Hide	C60H98N22O12	1
1	Ki > 10000 nM Bioactivity Info	TI LI LO TS
CP0404175 Compound Info	(2S)-1-[(2S)-2-[[(2R)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2R)-2-[[2-[[2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]acetyl]amino]-3,4-dihydro-1H-naphthalene-2-carbonyl]amino]-4-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]propanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]-N-[(2S)-1,6-diamino-1-oxohexan-2-yl]pyrrolidine-2-carboxamide Show/Hide	C62H100N22O12	1
1	Ki > 10000 nM Bioactivity Info	TI LI LO TS
CP0436644 Compound Info	(2S)-1-[(2S)-2-[[(2R)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]acetyl]amino]-3,4-dihydro-1H-naphthalene-2-carbonyl]amino]-4-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]propanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]-N-[(2S)-1,6-diamino-1-oxohexan-2-yl]pyrrolidine-2-carboxamide Show/Hide	C62H100N22O12	1
1	Ki > 10000 nM Bioactivity Info	TI LI LO TS
CP0501076 Compound Info	(2S)-1-[(2S)-2-[[(2R)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[2-[[2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]acetyl]amino]-1,3-dihydroindene-2-carbonyl]amino]-4-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]propanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]-N-[(2S)-1,6-diamino-1-oxohexan-2-yl]pyrrolidine-2-carboxamide Show/Hide	C61H98N22O12	1
1	Ki > 10000 nM Bioactivity Info	TI LI LO TS
CP0380412 Compound Info	(3R,8R,11R,14S)-3-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-11-benzyl-N-[(2S)-5-(diaminomethylideneamino)-1-[[(2S)-5-(diaminomethylideneamino)-1-[[(2S,3S)-1-[[(2S)-5-(diaminomethylideneamino)-1-[(2S)-2-[[(2S)-1,6-diamino-1-oxohexan-2-yl]carbamoyl]pyrrolidin-1-yl]-1-oxopentan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-1-oxopentan-2-yl]amino]-1-oxopentan-2-yl]-2,5,10,13-tetraoxo-1,6,9,12-tetrazabicyclo[12.3.0]heptadecane-8-carboxamide Show/Hide	C65H103N23O13	1
1	Ki > 10000 nM Bioactivity Info	TI LI LO TS
CP0095956 Compound Info	zyklophin Show/Hide	C65H96N20O13	1
1	Ki > 10000 nM Bioactivity Info	TI LI LO TS
CP0499015 Compound Info	(N-alpha-benzyl)Tyr-Gly-Gly-Phe-D-Asn-Arg-Arg-Dap(Ac)-Arg-Pro-Lys-NH2 Show/Hide	C67H102N24O14	1
1	Ki > 10000 nM Bioactivity Info	TI LI LO TS
CP0376791 Compound Info	N-[(4R,4aS,7R,7aR,12bS)-4a,9-dihydroxy-3-prop-2-enyl-1,2,4,5,6,7,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinolin-7-yl]adamantane-2-carboxamide Show/Hide	C30H38N2O4	1
1	Ki > 100 nM Bioactivity Info	TI LI LO TS
CP0477029 Compound Info	N-[(4R,4aS,7R,7aR,12bS)-4a-hydroxy-9-methoxy-3-prop-2-enyl-1,2,4,5,6,7,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinolin-7-yl]-3-iodobenzamide Show/Hide	C27H29IN2O4	1
1	Ki > 100 nM Bioactivity Info	TI LI LO TS
CP0477030 Compound Info	N-[(4R,4aS,7R,7aR,12bS)-4a,9-dihydroxy-3-prop-2-enyl-1,2,4,5,6,7,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinolin-7-yl]cyclohexanecarboxamide Show/Hide	C26H34N2O4	1
1	Ki > 100 nM Bioactivity Info	TI LI LO TS
CP0488753 Compound Info	N-[(4R,4aS,7R,7aR,12bS)-4a,9-dihydroxy-3-prop-2-enyl-1,2,4,5,6,7,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinolin-7-yl]acetamide Show/Hide	C21H26N2O4	1
1	Ki > 100 nM Bioactivity Info	TI LI LO TS
CP0379614 Compound Info	(E)-N-[(4R,4aR,7R,7aR,12bS)-9-methoxy-3-methyl-2,4,4a,7,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7-yl]-3-(4-chlorophenyl)prop-2-enamide Show/Hide	C27H27ClN2O3	1
1	Ki > 100 nM Bioactivity Info	TI LI LO TS
CP0411621 Compound Info	(E)-N-[(4R,4aR,7R,7aR,12bS)-9-methoxy-3-methyl-2,4,4a,7,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7-yl]-3-(4-methoxyphenyl)prop-2-enamide Show/Hide	C28H30N2O4	1
1	Ki > 100 nM Bioactivity Info	TI LI LO TS
CP0432957 Compound Info	(E)-N-[(4R,4aR,7R,7aR,12bS)-9-methoxy-3-methyl-2,4,4a,7,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7-yl]-3-phenylprop-2-enamide Show/Hide	C27H28N2O3	1
1	Ki > 100 nM Bioactivity Info	TI LI LO TS
CP0487351 Compound Info	(E)-N-[(4R,4aR,7R,7aR,12bS)-9-methoxy-3-methyl-2,4,4a,7,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7-yl]-3-(3-nitrophenyl)prop-2-enamide Show/Hide	C27H27N3O5	1
1	Ki > 100 nM Bioactivity Info	TI LI LO TS
CP0517446 Compound Info	(E)-N-[(4R,4aR,7R,7aR,12bS)-9-methoxy-3-methyl-2,4,4a,7,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7-yl]-3-[4-(trifluoromethyl)phenyl]prop-2-enamide Show/Hide	C28H27F3N2O3	1
1	Ki > 100 nM Bioactivity Info	TI LI LO TS
CP0036843 Compound Info	(2S,4aR,6aR,7R,9S,10aS,10bR)-9-(acetyloxy)-2-(furan-3-yl)dodecahydro-6a,10b-dimethyl-4,10-dioxo-2H-naphtho-[2,1-c]pyran-7-carboxylic acid methyl ester Show/Hide	C23H28O8	1
1	Ki > 1000 nM Bioactivity Info	TI LI LO TS
CP0040101 Compound Info	2-(3,4-dichlorophenyl)-N-methyl-N-[(1R,2R)-2-pyrrolidin-1-ylcyclohexyl]acetamide Show/Hide	C19H26Cl2N2O	1
1	Ki > 1000 nM Bioactivity Info	TI LI LO TS
CP0372905 Compound Info	methyl (2S,4aR,6aR,7R,9S,10aS,10bR)-9-(1-ethoxyethoxy)-2-(furan-3-yl)-6a,10b-dimethyl-4,10-dioxo-2,4a,5,6,7,8,9,10a-octahydro-1H-benzo[f]isochromene-7-carboxylate Show/Hide	C25H34O8	1
1	Ki > 1000 nM Bioactivity Info	TI LI LO TS
CP0372906 Compound Info	methyl (2S,4aR,6aR,7R,9S,10aS,10bR)-2-(furan-3-yl)-9-(2-methoxypropan-2-yloxy)-6a,10b-dimethyl-4,10-dioxo-2,4a,5,6,7,8,9,10a-octahydro-1H-benzo[f]isochromene-7-carboxylate Show/Hide	C25H34O8	1
1	Ki > 1000 nM Bioactivity Info	TI LI LO TS
CP0372907 Compound Info	methyl (2S,4aR,6aR,7R,9S,10aS,10bR)-2-(furan-3-yl)-6a,10b-dimethyl-4,10-dioxo-9-(phenylmethoxymethoxy)-2,4a,5,6,7,8,9,10a-octahydro-1H-benzo[f]isochromene-7-carboxylate Show/Hide	C29H34O8	1
1	Ki > 1000 nM Bioactivity Info	TI LI LO TS
CP0372908 Compound Info	methyl (2S,4aR,6aR,7R,9S,10aS,10bR)-2-(furan-3-yl)-6a,10b-dimethyl-9-[(2-methylpropan-2-yl)oxymethoxy]-4,10-dioxo-2,4a,5,6,7,8,9,10a-octahydro-1H-benzo[f]isochromene-7-carboxylate Show/Hide	C26H36O8	1
1	Ki > 1000 nM Bioactivity Info	TI LI LO TS
CP0372909 Compound Info	methyl (2S,4aR,6aR,7R,9S,10aS,10bR)-2-(furan-3-yl)-6a,10b-dimethyl-4,10-dioxo-9-(propan-2-yloxymethoxy)-2,4a,5,6,7,8,9,10a-octahydro-1H-benzo[f]isochromene-7-carboxylate Show/Hide	C25H34O8	1
1	Ki > 1000 nM Bioactivity Info	TI LI LO TS
CP0372910 Compound Info	methyl (2S,4aR,6aR,7R,9S,10aS,10bR)-2-(furan-3-yl)-6a,10b-dimethyl-9-(methylsulfanylmethoxy)-4,10-dioxo-2,4a,5,6,7,8,9,10a-octahydro-1H-benzo[f]isochromene-7-carboxylate Show/Hide	C23H30O7S	1
1	Ki > 1000 nM Bioactivity Info	TI LI LO TS
CP0395483 Compound Info	methyl (2S,4aR,6aR,7R,9S,10aS,10bR)-9-(ethoxymethoxy)-2-(furan-3-yl)-6a,10b-dimethyl-4,10-dioxo-2,4a,5,6,7,8,9,10a-octahydro-1H-benzo[f]isochromene-7-carboxylate Show/Hide	C24H32O8	1
1	Ki > 1000 nM Bioactivity Info	TI LI LO TS
CP0395485 Compound Info	methyl (2S,4aR,6aR,7R,9S,10aS,10bR)-2-(furan-3-yl)-9-(methoxymethoxy)-6a,10b-dimethyl-4,10-dioxo-2,4a,5,6,7,8,9,10a-octahydro-1H-benzo[f]isochromene-7-carboxylate Show/Hide	C23H30O8	1
1	Ki > 1000 nM Bioactivity Info	TI LI LO TS
CP0399581 Compound Info	methyl (2S,4aR,6aR,7R,9S,10aS,10bR)-9-(2-fluoroethoxymethoxy)-2-(furan-3-yl)-6a,10b-dimethyl-4,10-dioxo-2,4a,5,6,7,8,9,10a-octahydro-1H-benzo[f]isochromene-7-carboxylate Show/Hide	C24H31FO8	1
1	Ki > 1000 nM Bioactivity Info	TI LI LO TS
CP0405101 Compound Info	methyl (2S,4aR,6aR,7R,9S,10aS,10bR)-2-(furan-3-yl)-6a,10b-dimethyl-4,10-dioxo-9-(propoxymethoxy)-2,4a,5,6,7,8,9,10a-octahydro-1H-benzo[f]isochromene-7-carboxylate Show/Hide	C25H34O8	1
1	Ki > 1000 nM Bioactivity Info	TI LI LO TS
CP0405102 Compound Info	methyl (2S,4aR,6aR,7R,9S,10aS,10bR)-9-(fluoromethoxy)-2-(furan-3-yl)-6a,10b-dimethyl-4,10-dioxo-2,4a,5,6,7,8,9,10a-octahydro-1H-benzo[f]isochromene-7-carboxylate Show/Hide	C22H27FO7	1
1	Ki > 1000 nM Bioactivity Info	TI LI LO TS
CP0433117 Compound Info	methyl (2S,4aR,6aR,7R,9S,10aS,10bR)-2-(furan-3-yl)-6a,10b-dimethyl-9-(oxan-2-yloxy)-4,10-dioxo-2,4a,5,6,7,8,9,10a-octahydro-1H-benzo[f]isochromene-7-carboxylate Show/Hide	C26H34O8	1
1	Ki > 1000 nM Bioactivity Info	TI LI LO TS
CP0433118 Compound Info	methyl (2S,4aR,6aR,7R,9S,10aS,10bR)-2-(furan-3-yl)-9-(2-methoxyethoxymethoxy)-6a,10b-dimethyl-4,10-dioxo-2,4a,5,6,7,8,9,10a-octahydro-1H-benzo[f]isochromene-7-carboxylate Show/Hide	C25H34O9	1
1	Ki > 1000 nM Bioactivity Info	TI LI LO TS
CP0433119 Compound Info	methyl (2S,4aR,6aR,7R,9S,10aS,10bR)-2-(furan-3-yl)-6a,10b-dimethyl-4,10-dioxo-9-(2,2,2-trifluoroethoxymethoxy)-2,4a,5,6,7,8,9,10a-octahydro-1H-benzo[f]isochromene-7-carboxylate Show/Hide	C24H29F3O8	1
1	Ki > 1000 nM Bioactivity Info	TI LI LO TS
CP0452799 Compound Info	methyl (2S,4aR,6aR,7R,9S,10aS,10bR)-2-(furan-3-yl)-6a,10b-dimethyl-4,10-dioxo-9-(2-trimethylsilylethoxymethoxy)-2,4a,5,6,7,8,9,10a-octahydro-1H-benzo[f]isochromene-7-carboxylate Show/Hide	C27H40O8Si	1
1	Ki > 1000 nM Bioactivity Info	TI LI LO TS
CP0452800 Compound Info	methyl (2S,4aR,6aR,7R,9S,10aS,10bR)-9-(butoxymethoxy)-2-(furan-3-yl)-6a,10b-dimethyl-4,10-dioxo-2,4a,5,6,7,8,9,10a-octahydro-1H-benzo[f]isochromene-7-carboxylate Show/Hide	C26H36O8	1
1	Ki > 1000 nM Bioactivity Info	TI LI LO TS
CP0845069 Compound Info	salvinorin B 1-ethoxyethyl ether Show/Hide	C25H35ClO8	1
1	Ki > 1000 nM Bioactivity Info	TI LI LO TS
CP0139686 Compound Info	(2S,4aR,6aR,7R,9S,10aS,10bR)-methyl 9-acetoxy-2-(methoxymethyl)-6a,10b-dimethyl-4,10-dioxododecahydro-1H-benzo[f]isochromene-7-carboxylate Show/Hide	C21H30O8	1
1	Ki > 1000 nM Bioactivity Info	TI LI LO TS
CP0214838 Compound Info	(2S,4aR,6aR,7R,9S,10aS,10bR)-dimethyl 9-acetoxy-6a,10b-dimethyl-4,10-dioxododecahydro-1H-benzo[f]isochromene-2,7-dicarboxylate Show/Hide	C21H28O9	1
1	Ki > 1000 nM Bioactivity Info	TI LI LO TS
CP0323771 Compound Info	(2S,4aR,6aR,7R,9S,10aS,10bR)-methyl 9-acetoxy-2-(ethoxymethyl)-6a,10b-dimethyl-4,10-dioxododecahydro-1H-benzo[f]isochromene-7-carboxylate Show/Hide	C22H32O8	1
1	Ki > 1000 nM Bioactivity Info	TI LI LO TS
CP0323885 Compound Info	(2S,4aR,6aR,7R,9S,10aS,10bR)-2-isopropyl 7-methyl 9-acetoxy-6a,10b-dimethyl-4,10-dioxododecahydro-1H-benzo[f]isochromene-2,7-dicarboxylate Show/Hide	C23H32O9	1
1	Ki > 1000 nM Bioactivity Info	TI LI LO TS
CP0372800 Compound Info	(2S,4aR,6aR,7R,9S,10aS,10bR)-methyl 9-acetoxy-6a,10b-dimethyl-4,10-dioxo-2-(pyrazine-2-carbonyl)dodecahydro-1H-benzo[f]isochromene-7-carboxylate Show/Hide	C24H28N2O8	1
1	Ki > 1000 nM Bioactivity Info	TI LI LO TS
CP0372807 Compound Info	(2S,4aR,6aR,7R,9S,10aS,10bR)-methyl 9-acetoxy-2-(2-bromofuran-3-yl)-6a,10b-dimethyl-4,10-dioxo-dodecahydro-1H-benzo[f]isochromene-7-carboxylate Show/Hide	C23H27BrO8	1
1	Ki > 1000 nM Bioactivity Info	TI LI LO TS
CP0372808 Compound Info	(2S,4aR,6aR,7R,9S,10aS,10bR)-methyl 9-acetoxy-2-((S)-furan-2-yl(hydroxy)methyl)-6a,10b-dimethyl-4,10-dioxododecahydro-1H-benzo[f]isochromene-7-carboxylate Show/Hide	C24H30O9	1
1	Ki > 1000 nM Bioactivity Info	TI LI LO TS
CP0373868 Compound Info	(2S,4aR,6aR,7R,9S,10aS,10bR)-methyl 9-acetoxy-2-(acetoxymethyl)-6a,10b-dimethyl-4,10-dioxododecahydro-1H-benzo[f]isochromene-7-carboxylate Show/Hide	C22H30O9	1
1	Ki > 1000 nM Bioactivity Info	TI LI LO TS
CP0391771 Compound Info	12-epi-Salvinorin A Show/Hide	C23H28O8	1
1	Ki > 1000 nM Bioactivity Info	TI LI LO TS
CP0406037 Compound Info	(2S,4aR,6aR,7R,9S,10aS,10bR)-methyl 9-acetoxy-6a,10b-dimethyl-4,10-dioxo-2-(thiophene-2-carbonyl)dodecahydro-1H-benzo[f]isochromene-7-carboxylate Show/Hide	C24H28O8S	1
1	Ki > 1000 nM Bioactivity Info	TI LI LO TS
CP0414180 Compound Info	(2S,4aR,6aR,7R,9S,10aS,10bR)-methyl 9-acetoxy-6a,10b-dimethyl-4,10-dioxo-2-(2-vinylfuran-3-yl)dodecahydro-1H-benzo[f]isochromene-7-carboxylate Show/Hide	C25H30O8	1
1	Ki > 1000 nM Bioactivity Info	TI LI LO TS
CP0423234 Compound Info	(2S,4aR,6aR,7R,9S,10aS,10bR)-2-ethyl 7-methyl 9-acetoxy-6a,10b-dimethyl-4,10-dioxododecahydro-1H-benzo[f]isochromene-2,7-dicarboxylate Show/Hide	C22H30O9	1
1	Ki > 1000 nM Bioactivity Info	TI LI LO TS
CP0467297 Compound Info	(2S,4aR,6aR,7R,9S,10aS,10bR)-9-acetoxy-7-(methoxycarbonyl)-6a,10b-dimethyl-4,10-dioxododecahydro-1H-benzo[f]isochromene-2-carboxylic acid Show/Hide	C20H26O9	1
1	Ki > 1000 nM Bioactivity Info	TI LI LO TS
CP0067334 Compound Info	(2S,4aR,6aR,7R,9S,10aS,10bR)-methyl 9-acetoxy-6a,10b-dimethyl-2-(3-methyl-1,2,4-oxadiazol-5-yl)-4,10-dioxo-dodecahydro-1H-benzo[f]isochromene-7-carboxylate Show/Hide	C22H28N2O8	1
1	Ki > 1000 nM Bioactivity Info	TI LI LO TS
CP0415137 Compound Info	(2S,4aR,6aR,7R,9S,10aS,10bR)-methyl 9-acetoxy-6a,10b-dimethyl-2-(1-methyl-1H-1,2,3-triazol-4-yl)-4,10-dioxododecahydro-1H-benzo[f]isochromene-7-carboxylate Show/Hide	C22H29N3O7	1
1	Ki > 1000 nM Bioactivity Info	TI LI LO TS
CP0415138 Compound Info	(2S,4aR,6aR,7R,9S,10aS,10bR)-methyl 9-acetoxy-2-(1-benzyl-1H-1,2,3-triazol-4-yl)-6a,10b-dimethyl-4,10-dioxododecahydro-1H-benzo[f]isochromene-7-carboxylate Show/Hide	C28H33N3O7	1
1	Ki > 1000 nM Bioactivity Info	TI LI LO TS
CP0435054 Compound Info	(2S,4aR,6aR,7R,9S,10aS,10bR)-methyl 9-acetoxy-6a,10b-dimethyl-4,10-dioxo-2-(1H-1,2,3-triazol-4-yl)dodecahydro-1H-benzo[f]isochromene-7-carboxylate Show/Hide	C21H27N3O7	1
1	Ki > 1000 nM Bioactivity Info	TI LI LO TS
CP0459737 Compound Info	(2S,4aR,6aR,7R,9S,10aS,10bR)-methyl 9-acetoxy-6a,10b-dimethyl-4,10-dioxo-2-(1-(pivaloyloxymethyl)-1H-1,2,3-triazol-4-yl)dodecahydro-1H-benzo[f]isochromene-7-carboxylate Show/Hide	C27H37N3O9	1
1	Ki > 1000 nM Bioactivity Info	TI LI LO TS
CP0459760 Compound Info	(2S,4aS,6aR,7R,9S,10aS,10bR)-methyl 9-acetoxy-6a,10b-dimethyl-4,10-dioxo-2-(1H-1,2,3-triazol-4-yl)dodecahydro-1H-benzo[f]isochromene-7-carboxylate Show/Hide	C21H27N3O7	1
1	Ki > 1000 nM Bioactivity Info	TI LI LO TS
CP0500818 Compound Info	(2S,4aR,6aR,7R,9S,10aS,10bR)-methyl 9-acetoxy-2-(1-ethyl-1H-1,2,3-triazol-4-yl)-6a,10b-dimethyl-4,10-dioxododecahydro-1H-benzo[f]isochromene-7-carboxylate Show/Hide	C23H31N3O7	1
1	Ki > 1000 nM Bioactivity Info	TI LI LO TS
CP0130404 Compound Info	methyl (2S,4aR,6aR,7R,9S,10aS,10bR)-2-(furan-3-yl)-9-hydroxy-6a,10b-dimethyl-4,10-dioxo-2,4a,5,6,7,8,9,10a-octahydro-1H-benzo[f]isochromene-7-carboxylate Show/Hide	C21H26O7	1
1	Ki > 1000 nM Bioactivity Info	TI LI LO TS
CP0380446 Compound Info	methyl (2S,4aS,6aR,7R,9S,10aS,10bR)-2-(furan-3-yl)-9-[2-(2-iodoethoxy)ethyl]-9-(methoxymethyl)-6a,10b-dimethyl-4,10-dioxo-1,2,4a,5,6,7,8,10a-octahydrobenzo[f]isochromene-7-carboxylate Show/Hide	C27H37IO8	1
1	Ki > 1000 nM Bioactivity Info	TI LI LO TS
CP0380447 Compound Info	methyl (2S,4aR,6aR,7R,9R,10aS,10bR)-9-ethyl-2-(furan-3-yl)-9-(methoxymethyl)-6a,10b-dimethyl-4,10-dioxo-1,2,4a,5,6,7,8,10a-octahydrobenzo[f]isochromene-7-carboxylate Show/Hide	C25H34O7	1
1	Ki > 1000 nM Bioactivity Info	TI LI LO TS
CP0380493 Compound Info	methyl (2S,4aS,6aR,7R,9R,10aS,10bR)-2-(furan-3-yl)-9-(methoxymethyl)-6a,9,10b-trimethyl-4,10-dioxo-1,2,4a,5,6,7,8,10a-octahydrobenzo[f]isochromene-7-carboxylate Show/Hide	C24H32O7	1
1	Ki > 1000 nM Bioactivity Info	TI LI LO TS
CP0380494 Compound Info	methyl (2S,4aR,6aR,7R,9R,10aS,10bR)-2-(furan-3-yl)-9-(methoxymethyl)-6a,9,10b-trimethyl-4,10-dioxo-1,2,4a,5,6,7,8,10a-octahydrobenzo[f]isochromene-7-carboxylate Show/Hide	C24H32O7	1
1	Ki > 1000 nM Bioactivity Info	TI LI LO TS
CP0401020 Compound Info	methyl (2S,4aR,6aR,7R,9S,10aS,10bR)-2-(furan-3-yl)-9-[2-(2-iodoethoxy)ethyl]-9-(methoxymethyl)-6a,10b-dimethyl-4,10-dioxo-1,2,4a,5,6,7,8,10a-octahydrobenzo[f]isochromene-7-carboxylate Show/Hide	C27H37IO8	1
1	Ki > 1000 nM Bioactivity Info	TI LI LO TS
CP0401022 Compound Info	methyl (2S,4aR,6aR,7R,9R,10aS,10bR)-2-(furan-3-yl)-9-(methoxymethyl)-6a,10b-dimethyl-4,10-dioxo-9-prop-2-enyl-1,2,4a,5,6,7,8,10a-octahydrobenzo[f]isochromene-7-carboxylate Show/Hide	C26H34O7	1
1	Ki > 1000 nM Bioactivity Info	TI LI LO TS
CP0401025 Compound Info	methyl (2S,4aS,6aR,7R,9R,10aS,10bR)-2-(furan-3-yl)-9-(methoxymethyl)-6a,10b-dimethyl-4,10-dioxo-9-prop-2-enyl-1,2,4a,5,6,7,8,10a-octahydrobenzo[f]isochromene-7-carboxylate Show/Hide	C26H34O7	1
1	Ki > 1000 nM Bioactivity Info	TI LI LO TS
CP0415580 Compound Info	methyl (2S,4aR,6aR,7R,9R,10aS,10bR)-2-(furan-3-yl)-9-(methoxymethyl)-6a,10b-dimethyl-4,10-dioxo-9-propyl-1,2,4a,5,6,7,8,10a-octahydrobenzo[f]isochromene-7-carboxylate Show/Hide	C26H36O7	1
1	Ki > 1000 nM Bioactivity Info	TI LI LO TS
CP0429093 Compound Info	methyl (2S,4aR,6aR,7R,9R,10aS,10bR)-2-(furan-3-yl)-9-(5-iodopentyl)-9-(methoxymethyl)-6a,10b-dimethyl-4,10-dioxo-1,2,4a,5,6,7,8,10a-octahydrobenzo[f]isochromene-7-carboxylate Show/Hide	C28H39IO7	1
1	Ki > 1000 nM Bioactivity Info	TI LI LO TS
CP0434780 Compound Info	methyl (2S,4aS,6aR,7R,9R,10aS,10bR)-9-ethyl-2-(furan-3-yl)-9-(methoxymethyl)-6a,10b-dimethyl-4,10-dioxo-1,2,4a,5,6,7,8,10a-octahydrobenzo[f]isochromene-7-carboxylate Show/Hide	C25H34O7	1
1	Ki > 1000 nM Bioactivity Info	TI LI LO TS
CP0458417 Compound Info	methyl (2S,4aS,6aR,7R,9R,10aS,10bR)-2-(furan-3-yl)-9-(methoxymethyl)-6a,10b-dimethyl-4,10-dioxo-9-propyl-1,2,4a,5,6,7,8,10a-octahydrobenzo[f]isochromene-7-carboxylate Show/Hide	C26H36O7	1
1	Ki > 1000 nM Bioactivity Info	TI LI LO TS
CP0477238 Compound Info	methyl (2S,4aS,6aR,7R,9R,10aS,10bR)-2-(furan-3-yl)-9-(5-iodopentyl)-9-(methoxymethyl)-6a,10b-dimethyl-4,10-dioxo-1,2,4a,5,6,7,8,10a-octahydrobenzo[f]isochromene-7-carboxylate Show/Hide	C28H39IO7	1
1	Ki > 1000 nM Bioactivity Info	TI LI LO TS
CP0468881 Compound Info	methyl (E)-2-[(1S,6S,7S,8aS)-6-ethyl-4'-methoxy-1'-methyl-3'-oxospiro[3,5,6,7,8,8a-hexahydro-2H-indolizine-1,2'-indole]-7-yl]-3-methoxyprop-2-enoate Show/Hide	C24H32N2O5	1
1	Ki > 1000 nM Bioactivity Info	TI LI LO TS

Cell Line ID: CL001010 , CHO-hgamma

Cell Line Info

Cell Line ID: CL000006 , HEK293

Cell Line Info

Biochemical Assays

Compound ID	Compound Name	Compound Formula
CP0038418 Compound Info	13-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-7-benzyl-3,3,14,14-tetramethyl-6,9,12-trioxo-1,2-dithia-5,8,11-triaza-cyclotetradecane-4-carboxylic acid Show/Hide	C30H39N5O7S2	2
1	EC50 = 4.1 nM
2	IC50 = 4.1 nM
CP0045380 Compound Info	(2S)-2-amino-N-[(1R)-1-[({[(1S)-1-{N'-[(2S)-2-{2-[(2R)-2-[(2S)-2-amino-3-(4-hydroxyphenyl)propanamido]propanamido]acetamido}-3-phenylpropanoyl]hydrazinecarbonyl}-2-phenylethyl]carbamoyl}methyl)carbamoyl]ethyl]-3-(4-hydroxyphenyl)propanamide Show/Hide	C46H56N10O10	2
1	IC50 = 2.7 nM
2	IC50 = 27 nM
CP0328410 Compound Info	(2S)-2-amino-N-[(4S,10S,15S,21S)-21-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-10,15-dibenzyl-3,3,22,22-tetramethyl-5,8,11,14,17,20-hexaoxo-1,2-dithia-6,9,12,13,16,19-hexazacyclodocos-4-yl]-3-(4-hydroxyphenyl)propanamide Show/Hide	C50H62N10O10S2	1
1	IC50 = 7.2 nM
CP0041449 Compound Info	C18130 Show/Hide	C40H43N3O6	2
1	IC50 = 10.4 nM
2	Ki = 17.7 nM
CP0088373 Compound Info	(S)-2-[(S)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-acetylamino}-acetylamino)-3-phenyl-propionylamino]-4-methyl-pentanoic acid Show/Hide	C28H37N5O7	1
1	IC50 = 11.4 nM
CP0043354 Compound Info	2-[2-({(S)-2-[2-Amino-3-(4-hydroxy-phenyl)-propionyl]-4-methyl-1,2,3,4-tetrahydro-isoquinoline-3-carbonyl}-amino)-3-phenyl-propionylamino]-3-phenyl-propionic acid Show/Hide	C37H38N4O6	2
1	IC50 = 14.1 nM
2	Ki = 1.22 nM
CP0723478 Compound Info	2-[2-({2-[2-Amino-3-(4-hydroxy-phenyl)-propionyl]-1,2,3,4-tetrahydro-isoquinoline-3-carbonyl}-amino)-3-phenyl-propionylamino]-3-(4-amino-phenyl)-propionic acid Show/Hide	C37H39N5O6	1
1	IC50 = 19.9 nM
CP0148509 Compound Info	DYNORPHIN A (1-11) Show/Hide	C63H103N21O13	1
1	IC50 = 28.93 nM
CP0786258 Compound Info	2-[2-({2-[2-Amino-3-(4-hydroxy-phenyl)-propionyl]-1,2,3,4-tetrahydro-isoquinoline-3-carbonyl}-amino)-3-(4-amino-phenyl)-propionylamino]-3-phenyl-propionic acid Show/Hide	C37H39N5O6	1
1	IC50 = 36.2 nM
CP0050068 Compound Info	(1S,2S,13R,21R)-22-(cyclopropylmethyl)-14-oxa-11,22-diazaheptacyclo[13.9.1.01,13.02,21.04,12.05,10.019,25]pentacosa-4(12),5,7,9,15,17,19(25)-heptaene-2,16-diol Show/Hide	C26H26N2O3	2
1	Kd = 0.631 nM
2	Ki = 0.5 nM
CP0722817 Compound Info	SID56463016 Show/Hide	C26H27ClN2O3	1
1	Ki = 0.22 nM
CP0041255 Compound Info	(+)-4-((alpha R)-((2S,5R)-4-allyl-2,5-dimethylpiperazin-1-yl)(3-methoxyphenyl)methyl)-N,N-diethylbenzamide Show/Hide	C28H39N3O2	2
1	Ki = 1.57 nM
2	Ki = 1.7 nM
CP0047082 Compound Info	(2S)-1-[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-3-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]-N-[(2S)-1,6-diamino-1-oxohexan-2-yl]pyrrolidine-2-carboxamide Show/Hide	C63H104N22O12	1
1	Ki = 13.5 nM
CP0054764 Compound Info	2-[(1S,2S,13R,21R)-22-(cyclopropylmethyl)-2,16-dihydroxy-14-oxa-11,22-diazaheptacyclo[13.9.1.01,13.02,21.04,12.05,10.019,25]pentacosa-4(12),5(10),6,8,15,17,19(25)-heptaen-7-yl]guanidine Show/Hide	C27H29N5O3	1
1	Ki = 24.8 nM

Cite

About MolBiC

Correspondence

Prof. Feng ZHU

Prof. Leo, Lianyi Han