General Information of the Cell Line
Cell Line ID
CL000386
Cell Line Name
Flp-In-CHO
Synonyms
Flp-In CHO
CHO Flp-In
CHO-Flp-In
Category
Spontaneously immortalized cell line
Organism
Cricetulus griseus (Chinese hamster)
Cellosaurus ID
CVCL_U424
Tissue Information
Ovary
Disease None
Map of Molecular Bioactivity Related to the Cell Line
Map of Molecular Bioactivity Related to the Cell Line

Cell Line
Protein
Compound

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Cell Line
Protein ID: PT01513, 5-hydroxytryptamine receptor 5A
Compound ID Compound Name Compound Formula
CP0848197
(E)-5-((5-bromo-1H-indol-3-yl)methylene)-2-iminoimidazolidin-4-one
   Show/Hide
C12H9BrN4O
 1
1
Ki = 89 nM
   TI
   LI
   LO
   TS
CP0121280
7-[2-[2-(3-chlorophenyl)ethylamino]ethyl]quinolin-2-amine
   Show/Hide
C19H20ClN3
 1
1
Ki < 100 nM
   TI
   LI
   LO
   TS
CP0874532
(E)-5-((1H-indol-3-yl)methylene)-2-iminoimidazolidin-4-one
   Show/Hide
C12H10N4O
 1
1
Ki = 101 nM
   TI
   LI
   LO
   TS
CP0848620
(E)-5-((7-bromo-1H-indol-3-yl)methylene)-2-iminoimidazolidin-4-one
   Show/Hide
C12H9BrN4O
 1
1
Ki = 112 nM
   TI
   LI
   LO
   TS
CP0861380
(E)-5-((4-bromo-1H-indol-3-yl)methylene)-2-iminoimidazolidin-4-one
   Show/Hide
C12H9BrN4O
 1
1
Ki = 123 nM
   TI
   LI
   LO
   TS
CP0846923
(E)-5-((6-bromo-1H-indol-3-yl)methylene)-2-iminoimidazolidin-4-one
   Show/Hide
C12H9BrN4O
 1
1
Ki = 184 nM
   TI
   LI
   LO
   TS
CP0156479
(+)-N-methyl-laurotetanine
   Show/Hide
C20H23NO4
 1
1
Ki = 566 nM
   TI
   LI
   LO
   TS
CP0248165
2-benzyl-5-(3-methoxyphenyl)-1,3-dihydroisoindole
   Show/Hide
C22H21NO
 1
1
Ki = 875 nM
   TI
   LI
   LO
   TS
CP0198450
1-[5,5-bis(4-fluorophenyl)pentyl]-4-[4-chloro-3-(trifluoromethyl)phenyl]piperidin-4-ol
   Show/Hide
C29H29ClF5NO
 1
1
Ki = 894 nM
   TI
   LI
   LO
   TS
CP0168317
1-(4,4-bis(4-fluorophenyl)butyl)-4-(4-chloro-3-(trifluoromethyl)phenyl)piperidin-4-ol
   Show/Hide
C28H27ClF5NO
 1
1
Ki = 1000 nM
   TI
   LI
   LO
   TS
CP0860580
(E)-5-((4-bromo-1H-indol-3-yl)methylene)-2-imino-3-methylimidazolidin-4-one
   Show/Hide
C13H11BrN4O
 1
1
Ki = 1282 nM
   TI
   LI
   LO
   TS
CP0167765
CHEMBL2058409
   Show/Hide
C13H11BrN4O
 1
1
Ki = 1323 nM
   TI
   LI
   LO
   TS
CP0146890
CHEMBL2058418
   Show/Hide
C14H13BrN4O
 1
1
Ki = 1425 nM
   TI
   LI
   LO
   TS
CP0237317
CHEMBL2058415
   Show/Hide
C14H13BrN4O
 1
1
Ki = 1454 nM
   TI
   LI
   LO
   TS
CP0886656
(E)-5-((7-bromo-1H-indol-3-yl)methylene)-2-imino-3-methylimidazolidin-4-one
   Show/Hide
C13H11BrN4O
 1
1
Ki = 1550 nM
   TI
   LI
   LO
   TS
CP0073146
benzyl 7-(4-cyclopentylpiperazin-1-yl)-3,4-dihydro-1H-isoquinoline-2-carboxylate
   Show/Hide
C26H33N3O2
 1
1
Ki = 1747 nM
   TI
   LI
   LO
   TS
CP0391120
(1S,2R)-1-ethyl-7-methoxy-2-methyl-3,4-dihydro-1H-naphthalen-2-amine
   Show/Hide
C14H21NO
 1
1
Ki = 1995.26 nM
   TI
   LI
   LO
   TS
CP0866621
(E)-5-((5-bromo-1H-indol-3-yl)methylene)-2-imino-3-methylimidazolidin-4-one
   Show/Hide
C13H11BrN4O
 1
1
Ki = 2332 nM
   TI
   LI
   LO
   TS
CP0775034
(5Z)-5-((7-bromo-1H-indol-3-yl)methylene)-2-(methylimino)imidazolidin-4-one
   Show/Hide
C13H11BrN4O
 1
1
Ki = 3324 nM
   TI
   LI
   LO
   TS
CP0699214
(5Z)-5-((4-bromo-1H-indol-3-yl)methylene)-2-(methylimino)imidazolidin-4-one
   Show/Hide
C13H11BrN4O
 1
1
Ki = 3372 nM
   TI
   LI
   LO
   TS
CP0314578
4-[4-chloro-3-(trifluoromethyl)phenyl]-1-[4-(4-fluoro-N-(4-fluorophenyl)anilino)butyl]piperidin-4-ol
   Show/Hide
C28H28ClF5N2O
 1
1
Ki = 4152 nM
   TI
   LI
   LO
   TS
CP0114042
5-[(6-bromoindol-3-ylidene)methyl]-1,3-dimethyl-2-methyliminoimidazol-4-ol
   Show/Hide
C15H15BrN4O
 1
1
Ki = 4681 nM
   TI
   LI
   LO
   TS
CP0315737
2-[4-(1H-imidazol-5-ylmethyl)-5-phenyl-4,5-dihydro-1,3-thiazol-2-yl]phenol
   Show/Hide
C19H17N3OS
 1
1
Ki = 4700 nM
   TI
   LI
   LO
   TS
CP0202831
4-[4-chloro-3-(trifluoromethyl)phenyl]-1-[4-(4-methoxy-N-(4-methoxyphenyl)anilino)butyl]piperidin-4-ol
   Show/Hide
C30H34ClF3N2O3
 1
1
Ki = 4973 nM
   TI
   LI
   LO
   TS
CP0114039
CHEMBL2058426
   Show/Hide
C15H15BrN4O
 1
1
Ki = 5080 nM
   TI
   LI
   LO
   TS
CP0787573
(E)-5-((6-bromo-1H-indol-3-yl)methylene)-2-imino-3-methylimidazolidin-4-one
   Show/Hide
C13H11BrN4O
 1
1
Ki = 5355 nM
   TI
   LI
   LO
   TS
CP0244206
7-[4-imidazo[1,2-a]pyridin-5-yl-3-(trifluoromethyl)phenoxy]thieno[2,3-c]pyridine
   Show/Hide
C21H12F3N3OS
 1
1
Ki = 6200 nM
   TI
   LI
   LO
   TS
CP0257640
CHEMBL1170237
   Show/Hide
C14H13BrN4O
 1
1
Ki = 6725 nM
   TI
   LI
   LO
   TS
CP0176519
(4R,5S)-4-(1H-imidazol-5-ylmethyl)-5-methyl-2-phenyl-4,5-dihydro-1,3-thiazole
   Show/Hide
C14H15N3S
 1
1
Ki = 6800 nM
   TI
   LI
   LO
   TS
CP0114041
CHEMBL2058429
   Show/Hide
C15H15BrN4O
 1
1
Ki = 6913 nM
   TI
   LI
   LO
   TS
CP0369306
4-[4-imidazo[1,2-a]pyridin-5-yl-3-(trifluoromethyl)phenoxy]furo[3,2-c]pyridine
   Show/Hide
C21H12F3N3O2
 1
1
Ki = 7400 nM
   TI
   LI
   LO
   TS
CP0237316
CHEMBL2058419
   Show/Hide
C14H13BrN4O
 1
1
Ki = 7828 nM
   TI
   LI
   LO
   TS
CP0110111
[(4S,5S)-5-methyl-2-thiophen-3-yl-4,5-dihydro-1,3-thiazol-4-yl]methanol
   Show/Hide
C9H11NOS2
 1
1
Ki = 8200 nM
   TI
   LI
   LO
   TS
CP0210541
CHEMBL2058427
   Show/Hide
C15H15BrN4O
 1
1
Ki = 9118 nM
   TI
   LI
   LO
   TS
CP0064188
4-[4-(6-methylimidazo[1,2-a]pyrazin-5-yl)-3-(trifluoromethyl)phenoxy]furo[3,2-c]pyridine
   Show/Hide
C21H13F3N4O2
 1
1
Ki = 9500 nM
   TI
   LI
   LO
   TS
CP0055735
5-(6-Bromo-1H-indol-3-ylmethylene)-2-imino-1,3-dimethyl-imidazolidin-4-one
   Show/Hide
C14H13BrN4O
 1
1
Ki = 9621 nM
   TI
   LI
   LO
   TS
CP0002070
1-(1H-Indol-3-yl)-2-propanamine
   Show/Hide
C11H14N2
 1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS
CP0002071
N-[2-(5-methoxy-1H-indol-3-yl)ethyl]-N-prop-2-enylprop-2-en-1-amine
   Show/Hide
C17H22N2O
 1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS
CP0054519
(1R,12R,13S,17R,21S)-12-ethyl-18-propyl-7-(trifluoromethyl)-10,18-diazapentacyclo[11.7.1.02,11.04,9.017,21]henicosa-2(11),3,5,7,9-pentaene
   Show/Hide
C25H31F3N2
 1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS
CP0085414
(3aS,6R,6aS,9aR,9bR)-6-benzyl-1-methyl-3,3a,4,6,6a,7,8,9,9a,9b-decahydro-2H-benzo[de]quinolin-5-one
   Show/Hide
C20H27NO
 1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS
CP0389578
benzyl 7-[4-(3-ethoxy-3-oxopropyl)piperazin-1-yl]-3,4-dihydro-1H-isoquinoline-2-carboxylate
   Show/Hide
C26H33N3O4
 1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS
CP0315736
2-[4-(1H-imidazol-5-ylmethyl)-4,5-dihydro-1,3-thiazol-2-yl]phenol
   Show/Hide
C13H13N3OS
 1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS
CP0315738
[(4S,5S)-5-methyl-2-phenyl-4,5-dihydro-1,3-thiazol-4-yl]methanol
   Show/Hide
C11H13NOS
 1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS
CP0315739
[(4S,5S)-2-(1H-indol-3-yl)-5-methyl-4,5-dihydro-1,3-thiazol-4-yl]methanol
   Show/Hide
C13H14N2OS
 1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS
CP0315740
[(4S,5S)-5-methyl-2-thiophen-2-yl-4,5-dihydro-1,3-thiazol-4-yl]methanol
   Show/Hide
C9H11NOS2
 1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS
CP0369530
methyl (2S)-2-[[(4S,5R)-2-(2-hydroxyphenyl)-5-methyl-4,5-dihydro-1,3-thiazole-4-carbonyl]amino]-3-(1H-imidazol-5-yl)propanoate
   Show/Hide
C18H20N4O4S
 1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS
CP0396119
2-[(3aR,6aS)-4,5,6,6a-tetrahydro-3aH-cyclopenta[d][1,3]thiazol-2-yl]phenol
   Show/Hide
C12H13NOS
 1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS
CP0396120
[(4S,5S)-5-methyl-2-(4-octoxyphenyl)-4,5-dihydro-1,3-thiazol-4-yl]methanol
   Show/Hide
C19H29NO2S
 1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS
CP0396121
[(4S,5S)-2-(4-butoxyphenyl)-5-methyl-4,5-dihydro-1,3-thiazol-4-yl]methanol
   Show/Hide
C15H21NO2S
 1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS
CP0396122
[(4S,5S)-2-(4-hexoxyphenyl)-5-methyl-4,5-dihydro-1,3-thiazol-4-yl]methanol
   Show/Hide
C17H25NO2S
 1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS
CP0396185
[(4S,5S)-5-methyl-2-[2-(methylamino)phenyl]-4,5-dihydro-1,3-thiazol-4-yl]methanol
   Show/Hide
C12H16N2OS
 1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS
CP0408362
(4S,5S)-4-(1H-imidazol-5-ylmethyl)-5-methyl-2-phenyl-4,5-dihydro-1,3-thiazole
   Show/Hide
C14H15N3S
 1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS
CP0444340
3-[(4S,5S)-4-(hydroxymethyl)-5-methyl-4,5-dihydro-1,3-thiazol-2-yl]naphthalen-2-ol
   Show/Hide
C15H15NO2S
 1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS
CP0444342
2-[(4S,5S)-4-(1H-imidazol-5-ylmethyl)-5-methyl-4,5-dihydro-1,3-thiazol-2-yl]phenol
   Show/Hide
C14H15N3OS
 1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS
CP0475794
[(4S,5S)-2-(furan-2-yl)-5-methyl-4,5-dihydro-1,3-thiazol-4-yl]methanol
   Show/Hide
C9H11NO2S
 1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS
CP0391121
(3S,4S)-4-ethyl-3,6-dimethyl-2,4-dihydrochromen-3-amine
   Show/Hide
C13H19NO
 1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS
CP0411059
(3S,4S)-4-ethyl-3-methyl-1-phenyl-2,4-dihydroquinolin-3-amine
   Show/Hide
C18H22N2
 1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS
CP0064183
4-[3-methyl-4-(6-methylimidazo[1,2-a]pyrazin-5-yl)phenoxy]furo[3,2-c]pyridine
   Show/Hide
C21H16N4O2
 1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS
CP0127400
(-)-Pramipexole
   Show/Hide
C10H17N3S
 1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS
CP0085824
2-[(4S,5R)-4-(hydroxymethyl)-5-methyl-4,5-dihydro-1,3-thiazol-2-yl]phenol
   Show/Hide
C11H13NO2S
 1
1
Ki > 10 nM
   TI
   LI
   LO
   TS
CP0110059
2-[(4S,5S)-4-(hydroxymethyl)-5-methyl-4,5-dihydro-1,3-thiazol-2-yl]phenol
   Show/Hide
C11H13NO2S
 1
1
Ki > 10 nM
   TI
   LI
   LO
   TS
CP0475795
2-[(4R,5R)-4-(hydroxymethyl)-5-methyl-4,5-dihydro-1,3-thiazol-2-yl]phenol
   Show/Hide
C11H13NO2S
 1
1
Ki > 10 nM
   TI
   LI
   LO
   TS
Protein family and CMB statistics Related to the Cell Line
Cell Lines Derived from the same Tissue Source (Ovary)
Cell Line Name Organism Disease
SW626 Homo sapiens (Human) Colon adenocarcinoma
FU-OV-1 Homo sapiens (Human) High grade ovarian serous adenocarcinoma
TOV-21G Homo sapiens (Human) Ovarian clear cell adenocarcinoma
ES-2 Homo sapiens (Human) Ovarian clear cell adenocarcinoma
A2780 Homo sapiens (Human) Ovarian endometrioid adenocarcinoma
A2780ADR Homo sapiens (Human) Ovarian endometrioid adenocarcinoma
IGROV-1 Homo sapiens (Human) Ovarian endometrioid adenocarcinoma
CHO Cricetulus griseus (Chinese hamster) -
CHO-K1 Cricetulus griseus (Chinese hamster) -
CHO/Galpha16 Cricetulus griseus (Chinese hamster) -
CHOP Cricetulus griseus (Chinese hamster) -
T-REx-CHO Cricetulus griseus (Chinese hamster) -
CHO Pro-4 MtxRII OuaR-2-4 Cricetulus griseus (Chinese hamster) -
CHO-DXB11 Cricetulus griseus (Chinese hamster) -
CHO-CPR C10 Cricetulus griseus (Chinese hamster) -
PathHunter CHO-K1 EDG1 beta-arrestin Cricetulus griseus (Chinese hamster) -
CHO-S Cricetulus griseus (Chinese hamster) -
CHO-7 Cricetulus griseus (Chinese hamster) -
CHO-T Cricetulus griseus (Chinese hamster) -
ValiScreen human CRTH2 Cricetulus griseus (Chinese hamster) -
PathHunter CHO-K1 GLP1R beta-arrestin-1 Cricetulus griseus (Chinese hamster) -
CHO-K1/CRE-Luc Cricetulus griseus (Chinese hamster) -
CHO-hTRPV1 Cricetulus griseus (Chinese hamster) -
Lec1 Cricetulus griseus (Chinese hamster) -
CHO-N9 Cricetulus griseus (Chinese hamster) -
CHO/IR Cricetulus griseus (Chinese hamster) -
CHO-K1/Gqi5 Cricetulus griseus (Chinese hamster) -
CHO-K9 Cricetulus griseus (Chinese hamster) -
CHO-A12 Cricetulus griseus (Chinese hamster) -
CHO E1a Cricetulus griseus (Chinese hamster) -
PathHunter CHO-K1 CXCR7 beta-arrestin Cricetulus griseus (Chinese hamster) -
R2/PCFT4 Cricetulus griseus (Chinese hamster) -
Chinese hamster RT16 Cricetulus griseus (Chinese hamster) -
CHO-A1 Cricetulus griseus (Chinese hamster) -
CHO-D-/aequorin Cricetulus griseus (Chinese hamster) -
CHO-DUKX-A2 Cricetulus griseus (Chinese hamster) -
Lec3.2.8.1 Cricetulus griseus (Chinese hamster) -
CellSensor NFAT-bla CHO-K1 Cricetulus griseus (Chinese hamster) -
Chinese hamster PC43-10 Cricetulus griseus (Chinese hamster) -
CHO-A3 Cricetulus griseus (Chinese hamster) -
CHO/VR1 Cricetulus griseus (Chinese hamster) -
CHO-hgamma Cricetulus griseus (Chinese hamster) -
CHO-1 Cricetulus griseus (Chinese hamster) -
CHO-03 Cricetulus griseus (Chinese hamster) -
CHO CGE Cricetulus griseus (Chinese hamster) -
CHO-CHRM2 Cricetulus griseus (Chinese hamster) -
CHO CRE-SPAP Cricetulus griseus (Chinese hamster) -
CHO 2B7 Cricetulus griseus (Chinese hamster) -
hMORCHO Cricetulus griseus (Chinese hamster) -
CHO Pro-5 Cricetulus griseus (Chinese hamster) -
CHO CCR3/2 Cricetulus griseus (Chinese hamster) -
PPLS-HA-GPR88 CHO Cricetulus griseus (Chinese hamster) -
hTRPV4/CHO Cricetulus griseus (Chinese hamster) -
CHO 1827 Cricetulus griseus (Chinese hamster) -
CHO ducX#98 Cricetulus griseus (Chinese hamster) -
CHO 1829 Cricetulus griseus (Chinese hamster) -
CHO-mtAEQ Cricetulus griseus (Chinese hamster) -
DHB-11 CHO Cricetulus griseus (Chinese hamster) -
CellSensor CRE-bla CHO-K1 Cricetulus griseus (Chinese hamster) -
PathHunter CHO-K1 GLP1R beta-arrestin-2 Cricetulus griseus (Chinese hamster) -
Sf21 Spodoptera frugiperda (Fall armyworm) -
Sf9 Spodoptera frugiperda (Fall armyworm) -
SF-12 Spodoptera frugiperda (Fall armyworm) -
Tni PRO Trichoplusia ni (Cabbage looper) -