General Information of the Cell Line
Cell Line ID
CL000643
Cell Line Name
CHO-K1/CRE-Luc
Synonyms
CHO-K1/CRE-Luciferase
Category
Spontaneously immortalized cell line
Organism
Cricetulus griseus (Chinese hamster)
Cellosaurus ID
CVCL_H414
Tissue Information
Ovary
Disease None
Map of Molecular Bioactivity Related to the Cell Line
Map of Molecular Bioactivity Related to the Cell Line

Cell Line
Protein
Compound

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Cell Line
Protein ID: PT01155, Growth hormone secretagogue receptor type 1
Compound ID Compound Name Compound Formula
CP0452228
N-[4,6-dichloro-3-(3,4-dichlorophenyl)-2-oxo-1H-indol-3-yl]-2-(1-ethylpiperidin-4-yl)acetamide
   Show/Hide
C23H23Cl4N3O2
 2
1
IC50 = 1 nM
   TI
   LI
   LO
   TS
2
Ki = 3 nM
   TI
   LI
   LO
   TS
CP0392090
N-[4,6-dichloro-3-(3,4-dichlorophenyl)-2-oxo-1H-indol-3-yl]-2-(4-ethylpiperazin-1-yl)acetamide
   Show/Hide
C22H22Cl4N4O2
 2
1
IC50 = 7 nM
   TI
   LI
   LO
   TS
2
Ki = 8 nM
   TI
   LI
   LO
   TS
CP0476871
N-[4,6-dichloro-3-(3,4-dichlorophenyl)-2-oxo-1H-indol-3-yl]-2-(4-methylpiperazin-1-yl)acetamide
   Show/Hide
C21H20Cl4N4O2
 1
1
IC50 = 24 nM
   TI
   LI
   LO
   TS
CP0446300
N-[4,6-dichloro-3-(3,4-dichlorophenyl)-2-oxo-1H-indol-3-yl]-2-[(3R)-3-(dimethylamino)pyrrolidin-1-yl]acetamide
   Show/Hide
C22H22Cl4N4O2
 1
1
IC50 = 25 nM
   TI
   LI
   LO
   TS
CP0381626
N-[4,6-dichloro-3-(3,4-dichlorophenyl)-2-oxo-1H-indol-3-yl]-2-(4-prop-2-enylpiperazin-1-yl)acetamide
   Show/Hide
C23H22Cl4N4O2
 2
1
IC50 = 38 nM
   TI
   LI
   LO
   TS
2
Ki = 121 nM
   TI
   LI
   LO
   TS
CP0481700
N-[(3S)-5,6-dichloro-3-(4-chlorophenyl)-2-oxo-1H-indol-3-yl]-2-(4-methylpiperazin-1-yl)acetamide
   Show/Hide
C21H21Cl3N4O2
 2
1
IC50 = 47 nM
   TI
   LI
   LO
   TS
2
Ki = 249 nM
   TI
   LI
   LO
   TS
CP0514012
N-[4,6-dichloro-3-(3,4-dichlorophenyl)-2-oxo-1H-indol-3-yl]-2-(1-ethylpiperidin-3-yl)acetamide
   Show/Hide
C23H23Cl4N3O2
 1
1
IC50 = 47 nM
   TI
   LI
   LO
   TS
CP0413980
N-[4,6-dichloro-3-(3,4-dichlorophenyl)-2-oxo-1H-indol-3-yl]-2-(4-methyl-1,4-diazepan-1-yl)acetamide
   Show/Hide
C22H22Cl4N4O2
 1
1
IC50 = 64 nM
   TI
   LI
   LO
   TS
CP0452229
N-[4,6-dichloro-3-(4-chlorophenyl)-2-oxo-1H-indol-3-yl]-2-(4-methylpiperazin-1-yl)acetamide
   Show/Hide
C21H21Cl3N4O2
 2
1
IC50 = 72 nM
   TI
   LI
   LO
   TS
2
Ki = 44 nM
   TI
   LI
   LO
   TS
CP0413976
N-[5,6-dichloro-3-(4-chlorophenyl)-2-oxo-1H-indol-3-yl]-2-(4-ethylpiperazin-1-yl)acetamide
   Show/Hide
C22H23Cl3N4O2
 2
1
IC50 = 110 nM
   TI
   LI
   LO
   TS
2
Ki = 202 nM
   TI
   LI
   LO
   TS
CP0523369
N-[4,6-dichloro-3-(3,4-dichlorophenyl)-2-oxo-1H-indol-3-yl]-2-[(3S)-3-(dimethylamino)pyrrolidin-1-yl]acetamide
   Show/Hide
C22H22Cl4N4O2
 1
1
IC50 = 110 nM
   TI
   LI
   LO
   TS
CP0507783
N-[6-chloro-3-(3,4-dichlorophenyl)-2-oxo-1H-indol-3-yl]-2-(4-methylpiperazin-1-yl)acetamide
   Show/Hide
C21H21Cl3N4O2
 1
1
IC50 = 111 nM
   TI
   LI
   LO
   TS
CP0404930
N-[6-chloro-3-(4-chlorophenyl)-5-methyl-2-oxo-1H-indol-3-yl]-2-(4-ethylpiperazin-1-yl)acetamide
   Show/Hide
C23H26Cl2N4O2
 2
1
IC50 = 129 nM
   TI
   LI
   LO
   TS
2
Ki = 286 nM
   TI
   LI
   LO
   TS
CP0544485
N-[6-chloro-3-(4-chlorophenyl)-2-oxo-1H-indol-3-yl]-2-(4-methylpiperazin-1-yl)acetamide
   Show/Hide
C21H22Cl2N4O2
 1
1
IC50 = 140 nM
   TI
   LI
   LO
   TS
CP0404931
N-[6-chloro-3-(4-chlorophenyl)-5-methyl-2-oxo-1H-indol-3-yl]-2-(4-methylpiperazin-1-yl)acetamide
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C22H24Cl2N4O2
 2
1
IC50 = 213 nM
   TI
   LI
   LO
   TS
2
Ki = 392 nM
   TI
   LI
   LO
   TS
CP0392091
N-[6-chloro-3-(3,4-dichlorophenyl)-5-methyl-2-oxo-1H-indol-3-yl]-2-(4-methylpiperazin-1-yl)acetamide
   Show/Hide
C22H23Cl3N4O2
 2
1
IC50 = 220 nM
   TI
   LI
   LO
   TS
2
Ki > 1000 nM
   TI
   LI
   LO
   TS
CP0452230
N-[4,6-dichloro-3-(3,4-dichlorophenyl)-2-oxo-1H-indol-3-yl]-2-[4-(dimethylamino)piperidin-1-yl]acetamide
   Show/Hide
C23H24Cl4N4O2
 1
1
IC50 = 239 nM
   TI
   LI
   LO
   TS
CP0513260
N-[5-chloro-3-(4-chlorophenyl)-6-methyl-2-oxo-1H-indol-3-yl]-2-(4-methylpiperazin-1-yl)acetamide
   Show/Hide
C22H24Cl2N4O2
 1
1
IC50 = 251 nM
   TI
   LI
   LO
   TS
CP0413883
2-(4-methylpiperazin-1-yl)-N-[4,5,6-trichloro-3-(4-chlorophenyl)-2-oxo-1H-indol-3-yl]acetamide
   Show/Hide
C21H20Cl4N4O2
 1
1
IC50 = 273 nM
   TI
   LI
   LO
   TS
CP0452233
N-[6-chloro-3-(4-methoxyphenyl)-5-methyl-2-oxo-1H-indol-3-yl]-2-(4-methylpiperazin-1-yl)acetamide
   Show/Hide
C23H27ClN4O3
 1
1
IC50 = 525 nM
   TI
   LI
   LO
   TS
CP0476870
N-[5,6-dichloro-3-(4-methoxyphenyl)-2-oxo-1H-indol-3-yl]-2-(4-methylpiperazin-1-yl)acetamide
   Show/Hide
C22H24Cl2N4O3
 1
1
IC50 = 700 nM
   TI
   LI
   LO
   TS
CP0513906
N-[4-chloro-3-(4-chlorophenyl)-5-methyl-2-oxo-1H-indol-3-yl]-2-(4-methylpiperazin-1-yl)acetamide
   Show/Hide
C22H24Cl2N4O2
 1
1
IC50 = 1160 nM
   TI
   LI
   LO
   TS
CP0452232
N-[6-chloro-3-(3-chlorophenyl)-5-methyl-2-oxo-1H-indol-3-yl]-2-(4-methylpiperazin-1-yl)acetamide
   Show/Hide
C22H24Cl2N4O2
 1
1
IC50 = 1180 nM
   TI
   LI
   LO
   TS
CP0544484
N-[5,7-dichloro-3-(4-chlorophenyl)-2-oxo-1H-indol-3-yl]-2-(4-methylpiperazin-1-yl)acetamide
   Show/Hide
C21H21Cl3N4O2
 1
1
IC50 = 1390 nM
   TI
   LI
   LO
   TS
CP0540779
N-[3-(4-tert-butylphenyl)-5,6-dichloro-2-oxo-1H-indol-3-yl]-2-(4-methylpiperazin-1-yl)acetamide
   Show/Hide
C25H30Cl2N4O2
 1
1
IC50 = 1470 nM
   TI
   LI
   LO
   TS
CP0452746
N-[5,6-dichloro-3-(4-chlorophenyl)-2-oxo-1H-indol-3-yl]-2-(4-methylpiperidin-1-yl)acetamide
   Show/Hide
C22H22Cl3N3O2
 1
1
IC50 = 2540 nM
   TI
   LI
   LO
   TS
CP0381625
N-[4,6-dichloro-3-(3,4-dichlorophenyl)-2-oxo-1H-indol-3-yl]-2-(4-ethyl-3-oxopiperazin-1-yl)acetamide
   Show/Hide
C22H20Cl4N4O3
 1
1
IC50 = 2780 nM
   TI
   LI
   LO
   TS
CP0408594
N-[6-chloro-3-(4-chlorophenyl)-5-methyl-2-oxo-1H-indol-3-yl]-2-piperazin-1-ylacetamide
   Show/Hide
C21H22Cl2N4O2
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0413978
N-[6-chloro-3-(4-chlorophenyl)-5-methyl-2-oxo-1H-indol-3-yl]-2-(4-pyridin-4-ylpiperazin-1-yl)acetamide
   Show/Hide
C26H25Cl2N5O2
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0446301
N-[6-chloro-3-(2-chlorophenyl)-5-methyl-2-oxo-1H-indol-3-yl]-2-(4-methylpiperazin-1-yl)acetamide
   Show/Hide
C22H24Cl2N4O2
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0446327
N-[5,6-dichloro-3-(4-chlorophenyl)-2-oxo-1H-indol-3-yl]-2-[2-(dimethylamino)ethyl-methylamino]acetamide
   Show/Hide
C21H23Cl3N4O2
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0452231
N-[6-chloro-3-(2,4-dichlorophenyl)-5-methyl-2-oxo-1H-indol-3-yl]-2-(4-methylpiperazin-1-yl)acetamide
   Show/Hide
C22H23Cl3N4O2
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0553477
2-(4-benzylpiperazin-1-yl)-N-[6-chloro-3-(4-chlorophenyl)-5-methyl-2-oxo-1H-indol-3-yl]acetamide
   Show/Hide
C28H28Cl2N4O2
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0860645
(-)-N-(5,6-dichloro-3-(4-chlorophenyl)-2-oxoindolin-3-yl)-2-(4-methylpiperazin-1-yl)acetamide
   Show/Hide
C21H21Cl3N4O2
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
Protein family and CMB statistics Related to the Cell Line
Cell Lines Derived from the same Tissue Source (Ovary)
Cell Line Name Organism Disease
SW626 Homo sapiens (Human) Colon adenocarcinoma
FU-OV-1 Homo sapiens (Human) High grade ovarian serous adenocarcinoma
TOV-21G Homo sapiens (Human) Ovarian clear cell adenocarcinoma
ES-2 Homo sapiens (Human) Ovarian clear cell adenocarcinoma
A2780 Homo sapiens (Human) Ovarian endometrioid adenocarcinoma
A2780ADR Homo sapiens (Human) Ovarian endometrioid adenocarcinoma
IGROV-1 Homo sapiens (Human) Ovarian endometrioid adenocarcinoma
CHO Cricetulus griseus (Chinese hamster) -
CHO-K1 Cricetulus griseus (Chinese hamster) -
CHO/Galpha16 Cricetulus griseus (Chinese hamster) -
CHOP Cricetulus griseus (Chinese hamster) -
T-REx-CHO Cricetulus griseus (Chinese hamster) -
CHO Pro-4 MtxRII OuaR-2-4 Cricetulus griseus (Chinese hamster) -
Flp-In-CHO Cricetulus griseus (Chinese hamster) -
CHO-DXB11 Cricetulus griseus (Chinese hamster) -
CHO-CPR C10 Cricetulus griseus (Chinese hamster) -
PathHunter CHO-K1 EDG1 beta-arrestin Cricetulus griseus (Chinese hamster) -
CHO-S Cricetulus griseus (Chinese hamster) -
CHO-7 Cricetulus griseus (Chinese hamster) -
CHO-T Cricetulus griseus (Chinese hamster) -
ValiScreen human CRTH2 Cricetulus griseus (Chinese hamster) -
PathHunter CHO-K1 GLP1R beta-arrestin-1 Cricetulus griseus (Chinese hamster) -
CHO-hTRPV1 Cricetulus griseus (Chinese hamster) -
Lec1 Cricetulus griseus (Chinese hamster) -
CHO-N9 Cricetulus griseus (Chinese hamster) -
CHO/IR Cricetulus griseus (Chinese hamster) -
CHO-K1/Gqi5 Cricetulus griseus (Chinese hamster) -
CHO-K9 Cricetulus griseus (Chinese hamster) -
CHO-A12 Cricetulus griseus (Chinese hamster) -
CHO E1a Cricetulus griseus (Chinese hamster) -
PathHunter CHO-K1 CXCR7 beta-arrestin Cricetulus griseus (Chinese hamster) -
R2/PCFT4 Cricetulus griseus (Chinese hamster) -
Chinese hamster RT16 Cricetulus griseus (Chinese hamster) -
CHO-A1 Cricetulus griseus (Chinese hamster) -
CHO-D-/aequorin Cricetulus griseus (Chinese hamster) -
CHO-DUKX-A2 Cricetulus griseus (Chinese hamster) -
Lec3.2.8.1 Cricetulus griseus (Chinese hamster) -
CellSensor NFAT-bla CHO-K1 Cricetulus griseus (Chinese hamster) -
Chinese hamster PC43-10 Cricetulus griseus (Chinese hamster) -
CHO-A3 Cricetulus griseus (Chinese hamster) -
CHO/VR1 Cricetulus griseus (Chinese hamster) -
CHO-hgamma Cricetulus griseus (Chinese hamster) -
CHO-1 Cricetulus griseus (Chinese hamster) -
CHO-03 Cricetulus griseus (Chinese hamster) -
CHO CGE Cricetulus griseus (Chinese hamster) -
CHO-CHRM2 Cricetulus griseus (Chinese hamster) -
CHO CRE-SPAP Cricetulus griseus (Chinese hamster) -
CHO 2B7 Cricetulus griseus (Chinese hamster) -
hMORCHO Cricetulus griseus (Chinese hamster) -
CHO Pro-5 Cricetulus griseus (Chinese hamster) -
CHO CCR3/2 Cricetulus griseus (Chinese hamster) -
PPLS-HA-GPR88 CHO Cricetulus griseus (Chinese hamster) -
hTRPV4/CHO Cricetulus griseus (Chinese hamster) -
CHO 1827 Cricetulus griseus (Chinese hamster) -
CHO ducX#98 Cricetulus griseus (Chinese hamster) -
CHO 1829 Cricetulus griseus (Chinese hamster) -
CHO-mtAEQ Cricetulus griseus (Chinese hamster) -
DHB-11 CHO Cricetulus griseus (Chinese hamster) -
CellSensor CRE-bla CHO-K1 Cricetulus griseus (Chinese hamster) -
PathHunter CHO-K1 GLP1R beta-arrestin-2 Cricetulus griseus (Chinese hamster) -
Sf21 Spodoptera frugiperda (Fall armyworm) -
Sf9 Spodoptera frugiperda (Fall armyworm) -
SF-12 Spodoptera frugiperda (Fall armyworm) -
Tni PRO Trichoplusia ni (Cabbage looper) -