General Information of the Cell Line
Cell Line ID
CL000938
Cell Line Name
Chinese hamster RT16
Category
Spontaneously immortalized cell line
Organism
Cricetulus griseus (Chinese hamster)
Cellosaurus ID
CVCL_0214
Tissue Information
Ovary
Disease None
Map of Molecular Bioactivity Related to the Cell Line
Map of Molecular Bioactivity Related to the Cell Line

Cell Line
Protein
Compound

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Cell Line
Protein ID: PT04881, Folate receptor alpha
Compound ID Compound Name Compound Formula
CP0055020
AGF94
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C19H21N5O6S
 4
1
IC50 = 0.31 nM
   TI
   LI
   LO
   TS
2
IC50 = 0.38 nM
   TI
   LI
   LO
   TS
3
IC50 = 173 nM
   TI
   LI
   LO
   TS
4
IC50 > 1000 nM
   TI
   LI
   LO
   TS
CP0374708
(2S)-2-[[4-[3-(2-amino-4-oxo-3,7-dihydropyrrolo[2,3-d]pyrimidin-6-yl)propyl]thiophene-2-carbonyl]amino]pentanedioic acid
   Show/Hide
C19H21N5O6S
 2
1
IC50 = 0.33 nM
   TI
   LI
   LO
   TS
2
IC50 = 494 nM
   TI
   LI
   LO
   TS
CP0776522
(4-{[2-(2-Amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]-pyrimidin-6-yl)ethyl]thio}benzoyl)-L-glutamic Acid
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C20H21N5O6S
 1
1
IC50 = 0.51 nM
   TI
   LI
   LO
   TS
CP0206826
(2S)-2-[[5-[3-(2-amino-4-oxo-3,7-dihydropyrrolo[2,3-d]pyrimidin-6-yl)propyl]thiophene-3-carbonyl]amino]pentanedioic acid
   Show/Hide
C19H21N5O6S
 2
1
IC50 = 0.61 nM
   TI
   LI
   LO
   TS
2
IC50 = 506 nM
   TI
   LI
   LO
   TS
CP0705783
(4-{N-[2-(2-Amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]-pyrimidin-6-yl)ethyl]-2,2,2-trifluoroacetamido}benzoyl)-L-glutamic Acid
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C22H21F3N6O7
 1
1
IC50 = 1.08 nM
   TI
   LI
   LO
   TS
CP0383884
(2S)-2-[[5-[4-(2-amino-4-oxo-3,7-dihydropyrrolo[2,3-d]pyrimidin-6-yl)butyl]pyridine-2-carbonyl]amino]pentanedioic acid
   Show/Hide
C21H24N6O6
 2
1
IC50 = 1.27 nM
   TI
   LI
   LO
   TS
2
IC50 = 687 nM
   TI
   LI
   LO
   TS
CP0946262
(S)-2-(4-{[N-Methyl-(2-amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-6-yl)methylamino]-carbonyl}phenylcarbonyl)aminopentanedioic acid
   Show/Hide
C21H22N6O7
 1
1
IC50 = 1.4 nM
   TI
   LI
   LO
   TS
CP0946260
(S)-2-(3-{[N-methyl-(2-amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-6-yl)methylamino]-carbonyl}phenylcarbonyl)aminopentanedioic acid
   Show/Hide
C21H22N6O7
 1
1
IC50 = 1.78 nM
   TI
   LI
   LO
   TS
CP0330758
(S)-2-({5-[4-(2-Amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]-pyrimidin-6-yl)-butyl]-thiophene-2-carbonyl}-amino)-pentanedioicAcid
   Show/Hide
C20H23N5O6S
 1
1
IC50 = 1.82 nM
   TI
   LI
   LO
   TS
CP0874529
{4-[2-(2-Amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]-pyrimidin-6-yl)ethoxy]benzoyl}-L-glutamic Acid
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C20H21N5O7
 1
1
IC50 = 1.89 nM
   TI
   LI
   LO
   TS
CP0705782
(4-{N-[2-(2-Amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]-pyrimidin-6-yl)ethyl]formamido}benzoyl)-L-L-glutamic Acid
   Show/Hide
C21H22N6O7
 1
1
IC50 = 3.01 nM
   TI
   LI
   LO
   TS
CP0838078
(4-{[2-(2-Amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]-pyrimidin-6-yl)ethyl]amino}benzoyl)-L-glutamic Acid
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C20H22N6O6
 1
1
IC50 = 3.04 nM
   TI
   LI
   LO
   TS
CP0429653
(2S)-2-[[5-[4-(2-amino-4-oxo-3,7-dihydropyrrolo[2,3-d]pyrimidin-6-yl)but-1-ynyl]pyridine-2-carbonyl]amino]pentanedioic acid
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C21H20N6O6
 2
1
IC50 = 4.43 nM
   TI
   LI
   LO
   TS
2
IC50 > 1000 nM
   TI
   LI
   LO
   TS
CP0740290
(4-{N-[2-(2-Amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]-pyrimidin-6-yl)ethyl]acetamido}benzoyl)-L-glutamic Acid
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C22H24N6O7
 1
1
IC50 = 4.87 nM
   TI
   LI
   LO
   TS
CP0050307
(S)-2-(4-(4-(2-amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-6-yl)butyl)benzamido)pentanedioic acid
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C22H25N5O6
 2
1
IC50 = 6.3 nM
   TI
   LI
   LO
   TS
2
IC50 > 1000 nM
   TI
   LI
   LO
   TS
CP0419800
(2S)-2-[[5-[3-(2-amino-4-oxo-3,7-dihydropyrrolo[2,3-d]pyrimidin-6-yl)propyl]thiophene-2-carbonyl]amino]butanedioic acid
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C18H19N5O6S
 2
1
IC50 = 6.6 nM
   TI
   LI
   LO
   TS
2
IC50 > 1000 nM
   TI
   LI
   LO
   TS
CP0931090
(S)-2-(5-{[N-methyl-(2-amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-6-yl)methylamino]carbonyl}thiophene-2-carbonyl)aminopentanedioic acid
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C19H20N6O7S
 1
1
IC50 = 7.78 nM
   TI
   LI
   LO
   TS
CP0386884
(2S)-2-[[5-[3-(2-amino-4-oxo-3,7-dihydropyrrolo[2,3-d]pyrimidin-6-yl)propyl]thiophene-2-carbonyl]amino]hexanedioic acid
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C20H23N5O6S
 2
1
IC50 = 9.5 nM
   TI
   LI
   LO
   TS
2
IC50 > 1000 nM
   TI
   LI
   LO
   TS
CP0041026
(2S)-2-[(5-{methyl[(2-methyl-4-oxo-1,4-dihydroquinazolin-6-yl)methyl]amino}thiophen-2-yl)formamido]pentanedioic acid
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C21H22N4O6S
 2
1
IC50 = 15 nM
   TI
   LI
   LO
   TS
2
IC50 > 1000 nM
   TI
   LI
   LO
   TS
CP0383883
(2S)-2-[[6-[4-(2-amino-4-oxo-3,7-dihydropyrrolo[2,3-d]pyrimidin-6-yl)butyl]pyridine-3-carbonyl]amino]pentanedioic acid
   Show/Hide
C21H24N6O6
 2
1
IC50 = 15.02 nM
   TI
   LI
   LO
   TS
2
IC50 > 1000 nM
   TI
   LI
   LO
   TS
CP0386883
4-[[5-[3-(2-amino-4-oxo-3,7-dihydropyrrolo[2,3-d]pyrimidin-6-yl)propyl]thiophene-2-carbonyl]amino]butanoic acid
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C18H21N5O4S
 2
1
IC50 = 27.4 nM
   TI
   LI
   LO
   TS
2
IC50 > 1000 nM
   TI
   LI
   LO
   TS
CP0036368
(2S)-2-{[4-(2-{2-amino-4-oxo-1H,4H,7H-pyrrolo[2,3-d]pyrimidin-5-yl}ethyl)phenyl]formamido}pentanedioic acid
   Show/Hide
C20H21N5O6
 3
1
IC50 = 42 nM
   TI
   LI
   LO
   TS
2
IC50 = 388 nM
   TI
   LI
   LO
   TS
3
IC50 = 894 nM
   TI
   LI
   LO
   TS
CP0399631
(2S)-2-[[5-[5-(2-amino-4-oxo-3,7-dihydropyrrolo[2,3-d]pyrimidin-5-yl)pentyl]thiophene-2-carbonyl]amino]pentanedioic acid
   Show/Hide
C21H25N5O6S
 1
1
IC50 = 45.5 nM
   TI
   LI
   LO
   TS
CP0381988
(2S)-2-[[5-[4-(2-amino-4-oxo-3,7-dihydropyrrolo[2,3-d]pyrimidin-5-yl)butyl]thiophene-2-carbonyl]amino]pentanedioic acid
   Show/Hide
C20H23N5O6S
 1
1
IC50 = 49.3 nM
   TI
   LI
   LO
   TS
CP0379858
(2S)-2-[[5-[3-(2-amino-4-oxo-3,7-dihydropyrrolo[2,3-d]pyrimidin-6-yl)propyl]thiophene-2-carbonyl]amino]pentanoic acid
   Show/Hide
C19H23N5O4S
 2
1
IC50 = 55.7 nM
   TI
   LI
   LO
   TS
2
IC50 > 1000 nM
   TI
   LI
   LO
   TS
CP0461015
(2S)-2-[[5-[3-(2-amino-4-oxo-3,7-dihydropyrrolo[2,3-d]pyrimidin-5-yl)propyl]thiophene-2-carbonyl]amino]pentanedioic acid
   Show/Hide
C19H21N5O6S
 1
1
IC50 = 109 nM
   TI
   LI
   LO
   TS
CP0036197
2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)amino}phenyl)formamido]pentanedioic acid
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C20H22N8O5
 3
1
IC50 = 114 nM
   TI
   LI
   LO
   TS
2
IC50 = 216 nM
   TI
   LI
   LO
   TS
3
IC50 = 461 nM
   TI
   LI
   LO
   TS
CP0374710
(2S)-2-[[5-[3-(2,4-diaminofuro[2,3-d]pyrimidin-5-yl)propyl]thiophene-3-carbonyl]amino]pentanedioic acid
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C19H21N5O6S
 2
1
IC50 = 148 nM
   TI
   LI
   LO
   TS
2
IC50 > 1000 nM
   TI
   LI
   LO
   TS
CP0374709
(2S)-2-[[4-[3-(2,4-diaminofuro[2,3-d]pyrimidin-5-yl)propyl]thiophene-2-carbonyl]amino]pentanedioic acid
   Show/Hide
C19H21N5O6S
 2
1
IC50 = 154 nM
   TI
   LI
   LO
   TS
2
IC50 > 1000 nM
   TI
   LI
   LO
   TS
CP0383886
CHEBI:71223
   Show/Hide
C23H23N7O5
 2
1
IC50 = 168 nM
   TI
   LI
   LO
   TS
2
IC50 > 1000 nM
   TI
   LI
   LO
   TS
CP0383887
(2S)-2-[[6-[4-(2-amino-4-oxo-3,7-dihydropyrrolo[2,3-d]pyrimidin-6-yl)butyl]pyridine-2-carbonyl]amino]pentanedioic acid
   Show/Hide
C21H24N6O6
 2
1
IC50 = 186 nM
   TI
   LI
   LO
   TS
2
IC50 > 1000 nM
   TI
   LI
   LO
   TS
CP0383885
(2S)-2-[[6-[4-(2-amino-4-oxo-3,7-dihydropyrrolo[2,3-d]pyrimidin-6-yl)but-1-ynyl]pyridine-3-carbonyl]amino]pentanedioic acid
   Show/Hide
C21H20N6O6
 2
1
IC50 = 449 nM
   TI
   LI
   LO
   TS
2
IC50 > 1000 nM
   TI
   LI
   LO
   TS
CP0468983
(2S)-2-[[5-[2-(2-amino-4-oxo-3,7-dihydropyrrolo[2,3-d]pyrimidin-5-yl)ethyl]thiophene-2-carbonyl]amino]pentanedioic acid
   Show/Hide
C18H19N5O6S
 1
1
IC50 = 550 nM
   TI
   LI
   LO
   TS
CP0411313
5-[3-(2-amino-4-oxo-3,7-dihydropyrrolo[2,3-d]pyrimidin-6-yl)propyl]thiophene-2-carboxylic acid
   Show/Hide
C14H14N4O3S
 2
1
IC50 = 661 nM
   TI
   LI
   LO
   TS
2
IC50 > 1000 nM
   TI
   LI
   LO
   TS
CP0876574
(S)-2-(5-{[N-methyl-(2-amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-6-yl)methylamino]carbonyl}thiophene-3-carbonyl)aminopentanedioic acid
   Show/Hide
C19H20N6O7S
 1
1
IC50 = 867 nM
   TI
   LI
   LO
   TS
CP0200251
(2S)-2-[[5-[(2-amino-4-oxo-3,7-dihydropyrrolo[2,3-d]pyrimidin-5-yl)methyl]thiophene-2-carbonyl]amino]pentanedioic acid
   Show/Hide
C17H17N5O6S
 1
1
IC50 > 1000 nM
   TI
   LI
   LO
   TS
CP0399627
(2S)-2-[[5-[6-(2-amino-4-oxo-3,7-dihydropyrrolo[2,3-d]pyrimidin-5-yl)hexyl]thiophene-2-carbonyl]amino]pentanedioic acid
   Show/Hide
C22H27N5O6S
 1
1
IC50 > 1000 nM
   TI
   LI
   LO
   TS
CP0416461
(2S)-2-[[6-[4-(2-amino-4-oxo-3,7-dihydropyrrolo[2,3-d]pyrimidin-6-yl)but-1-ynyl]pyridine-2-carbonyl]amino]pentanedioic acid
   Show/Hide
C21H20N6O6
 1
1
IC50 > 1000 nM
   TI
   LI
   LO
   TS
CP0935714
(S)-2-(4-{[N-methyl-(2-amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-6-yl)methylamino]carbonyl}thiophene-2-carbonyl)aminopentanedioic acid
   Show/Hide
C19H20N6O7S
 1
1
IC50 > 1000 nM
   TI
   LI
   LO
   TS
CP0946261
(S)-2-(4-{[N-methyl-(2-amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-6-yl)methylamino]-sulfonyl}phenylcarbonyl)aminopentanedioic acid
   Show/Hide
C20H22N6O8S
 1
1
IC50 > 1000 nM
   TI
   LI
   LO
   TS
Protein family and CMB statistics Related to the Cell Line
Cell Lines Derived from the same Tissue Source (Ovary)
Cell Line Name Organism Disease
SW626 Homo sapiens (Human) Colon adenocarcinoma
FU-OV-1 Homo sapiens (Human) High grade ovarian serous adenocarcinoma
TOV-21G Homo sapiens (Human) Ovarian clear cell adenocarcinoma
ES-2 Homo sapiens (Human) Ovarian clear cell adenocarcinoma
A2780 Homo sapiens (Human) Ovarian endometrioid adenocarcinoma
A2780ADR Homo sapiens (Human) Ovarian endometrioid adenocarcinoma
IGROV-1 Homo sapiens (Human) Ovarian endometrioid adenocarcinoma
CHO Cricetulus griseus (Chinese hamster) -
CHO-K1 Cricetulus griseus (Chinese hamster) -
CHO/Galpha16 Cricetulus griseus (Chinese hamster) -
CHOP Cricetulus griseus (Chinese hamster) -
T-REx-CHO Cricetulus griseus (Chinese hamster) -
CHO Pro-4 MtxRII OuaR-2-4 Cricetulus griseus (Chinese hamster) -
Flp-In-CHO Cricetulus griseus (Chinese hamster) -
CHO-DXB11 Cricetulus griseus (Chinese hamster) -
CHO-CPR C10 Cricetulus griseus (Chinese hamster) -
PathHunter CHO-K1 EDG1 beta-arrestin Cricetulus griseus (Chinese hamster) -
CHO-S Cricetulus griseus (Chinese hamster) -
CHO-7 Cricetulus griseus (Chinese hamster) -
CHO-T Cricetulus griseus (Chinese hamster) -
ValiScreen human CRTH2 Cricetulus griseus (Chinese hamster) -
PathHunter CHO-K1 GLP1R beta-arrestin-1 Cricetulus griseus (Chinese hamster) -
CHO-K1/CRE-Luc Cricetulus griseus (Chinese hamster) -
CHO-hTRPV1 Cricetulus griseus (Chinese hamster) -
Lec1 Cricetulus griseus (Chinese hamster) -
CHO-N9 Cricetulus griseus (Chinese hamster) -
CHO/IR Cricetulus griseus (Chinese hamster) -
CHO-K1/Gqi5 Cricetulus griseus (Chinese hamster) -
CHO-K9 Cricetulus griseus (Chinese hamster) -
CHO-A12 Cricetulus griseus (Chinese hamster) -
CHO E1a Cricetulus griseus (Chinese hamster) -
PathHunter CHO-K1 CXCR7 beta-arrestin Cricetulus griseus (Chinese hamster) -
R2/PCFT4 Cricetulus griseus (Chinese hamster) -
CHO-A1 Cricetulus griseus (Chinese hamster) -
CHO-D-/aequorin Cricetulus griseus (Chinese hamster) -
CHO-DUKX-A2 Cricetulus griseus (Chinese hamster) -
Lec3.2.8.1 Cricetulus griseus (Chinese hamster) -
CellSensor NFAT-bla CHO-K1 Cricetulus griseus (Chinese hamster) -
Chinese hamster PC43-10 Cricetulus griseus (Chinese hamster) -
CHO-A3 Cricetulus griseus (Chinese hamster) -
CHO/VR1 Cricetulus griseus (Chinese hamster) -
CHO-hgamma Cricetulus griseus (Chinese hamster) -
CHO-1 Cricetulus griseus (Chinese hamster) -
CHO-03 Cricetulus griseus (Chinese hamster) -
CHO CGE Cricetulus griseus (Chinese hamster) -
CHO-CHRM2 Cricetulus griseus (Chinese hamster) -
CHO CRE-SPAP Cricetulus griseus (Chinese hamster) -
CHO 2B7 Cricetulus griseus (Chinese hamster) -
hMORCHO Cricetulus griseus (Chinese hamster) -
CHO Pro-5 Cricetulus griseus (Chinese hamster) -
CHO CCR3/2 Cricetulus griseus (Chinese hamster) -
PPLS-HA-GPR88 CHO Cricetulus griseus (Chinese hamster) -
hTRPV4/CHO Cricetulus griseus (Chinese hamster) -
CHO 1827 Cricetulus griseus (Chinese hamster) -
CHO ducX#98 Cricetulus griseus (Chinese hamster) -
CHO 1829 Cricetulus griseus (Chinese hamster) -
CHO-mtAEQ Cricetulus griseus (Chinese hamster) -
DHB-11 CHO Cricetulus griseus (Chinese hamster) -
CellSensor CRE-bla CHO-K1 Cricetulus griseus (Chinese hamster) -
PathHunter CHO-K1 GLP1R beta-arrestin-2 Cricetulus griseus (Chinese hamster) -
Sf21 Spodoptera frugiperda (Fall armyworm) -
Sf9 Spodoptera frugiperda (Fall armyworm) -
SF-12 Spodoptera frugiperda (Fall armyworm) -
Tni PRO Trichoplusia ni (Cabbage looper) -