| Compound ID |
Compound Name |
Compound Formula |
|
CP0570525
|
(4R)-4-[(1S,2R,13S,14S,17R,18R)-7-acetyl-2,9,9,18-tetramethyl-6,7-diazapentacyclo[11.7.0.02,10.04,8.014,18]icosa-4(8),5,10-trien-17-yl]-1-morpholin-4-ylpentan-1-one
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|
C33H49N3O3
|
2
|
| 1 |
EC50 = 130 nM
|
|
|
| 2 |
EC50 = 220 nM
|
|
|
|
CP0568279
|
(3R)-3-[(1S,2R,13S,14S,17R,18R)-7-acetyl-2,9,9,18-tetramethyl-5,7-diazapentacyclo[11.7.0.02,10.04,8.014,18]icosa-4(8),5,10-trien-17-yl]-1-morpholin-4-ylbutan-1-one
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|
C32H47N3O3
|
1
|
| 1 |
EC50 = 280 nM
|
|
|
|
CP0568378
|
(3S,7R,8S,9S,10R,13R,14S,17R)-17-[(2R)-7-ethyl-7-hydroxynonan-2-yl]-4,4,10,13-tetramethyl-1,2,3,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthrene-3,7-diol
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|
C32H56O3
|
1
|
| 1 |
EC50 = 410 nM
|
|
|
|
CP0574700
|
(3S,7R,8S,9S,10R,13R,14S,17R)-17-[(2R)-6-ethyl-6-hydroxyoctan-2-yl]-4,4,10,13-tetramethyl-1,2,3,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthrene-3,7-diol
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|
C31H54O3
|
1
|
| 1 |
EC50 = 410 nM
|
|
|
|
CP0576380
|
(3S,7R,8S,9S,10R,13R,14S,17R)-17-[(2R)-7-hydroxy-7-methyloctan-2-yl]-4,4,10,13-tetramethyl-1,2,3,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthrene-3,7-diol
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|
C30H52O3
|
1
|
| 1 |
EC50 = 410 nM
|
|
|
|
CP0576850
|
(2S)-2-[(1S,2R,13S,14S,17R,18S)-7-acetyl-2,9,9,18-tetramethyl-5,7-diazapentacyclo[11.7.0.02,10.04,8.014,18]icosa-4(8),5,10-trien-17-yl]-1-morpholin-4-ylpropan-1-one
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|
C31H45N3O3
|
1
|
| 1 |
EC50 = 410 nM
|
|
|
|
CP0578374
|
(3S,7R,8S,9S,10R,13R,14S,17R)-17-[(2R)-6-hydroxy-6-prop-2-enylnon-8-en-2-yl]-4,4,10,13-tetramethyl-1,2,3,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthrene-3,7-diol
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|
C33H54O3
|
1
|
| 1 |
EC50 = 410 nM
|
|
|
|
CP0579934
|
(3S,7R,8S,9S,10R,13R,14S,17R)-17-[(2R)-6-hydroxy-6-methylheptan-2-yl]-4,4,10,13-tetramethyl-1,2,3,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthrene-3,7-diol
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|
C29H50O3
|
1
|
| 1 |
EC50 = 410 nM
|
|
|
|
CP0576849
|
(4R)-N-(1-acetylpiperidin-4-yl)-4-[(1S,2R,13S,14S,17R,18R)-7-acetyl-2,9,9,18-tetramethyl-6,7-diazapentacyclo[11.7.0.02,10.04,8.014,18]icosa-4(8),5,10-trien-17-yl]pentanamide
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|
C36H54N4O3
|
1
|
| 1 |
EC50 = 430 nM
|
|
|
|
CP0579788
|
(3S,7R,8S,9S,10R,13R,14S,17R)-17-[(2R)-6-hydroxy-6-prop-2-enylnon-8-en-2-yl]-4,4,10,13-tetramethyl-1,2,3,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthrene-3,7-diol;hydrochloride
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|
C33H55ClO3
|
1
|
| 1 |
EC50 = 430 nM
|
|
|
|
CP0579933
|
(4R)-1-morpholin-4-yl-4-[(1S,2R,13S,14S,17R,18R)-2,9,9,18-tetramethyl-7-(2-methylpropanoyl)-5,7-diazapentacyclo[11.7.0.02,10.04,8.014,18]icosa-4(8),5,10-trien-17-yl]pentan-1-one
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|
C35H53N3O3
|
1
|
| 1 |
EC50 = 430 nM
|
|
|
|
CP0580241
|
(4R)-4-[(1S,2R,13S,14S,17R,18R)-7-acetyl-2,9,9,18-tetramethyl-6,7-diazapentacyclo[11.7.0.02,10.04,8.014,18]icosa-4(8),5,10-trien-17-yl]-N-(oxan-4-yl)pentanamide
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|
C34H51N3O3
|
1
|
| 1 |
EC50 = 480 nM
|
|
|
|
CP0580193
|
(4R)-4-[(1S,2R,13S,14S,17R,18R)-7-butanoyl-2,9,9,18-tetramethyl-5,7-diazapentacyclo[11.7.0.02,10.04,8.014,18]icosa-4(8),5,10-trien-17-yl]-1-morpholin-4-ylpentan-1-one
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|
C35H53N3O3
|
1
|
| 1 |
EC50 = 520 nM
|
|
|
|
CP0577941
|
ethyl (1S,2R,13S,14S,17R,18R)-2,9,9,18-tetramethyl-17-[(2R)-5-morpholin-4-yl-5-oxopentan-2-yl]-6,7-diazapentacyclo[11.7.0.02,10.04,8.014,18]icosa-4(8),5,10-triene-5-carboxylate
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|
C34H51N3O4
|
1
|
| 1 |
EC50 = 530 nM
|
|
|
|
CP0568366
|
1-[(1S,2R,13S,14S,17R,18R)-17-[(2R)-5-ethyl-5-hydroxyheptan-2-yl]-2,9,9,18-tetramethyl-5,7-diazapentacyclo[11.7.0.02,10.04,8.014,18]icosa-4(8),5,10-trien-7-yl]ethanone
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|
C33H52N2O2
|
1
|
| 1 |
EC50 = 630 nM
|
|
|
|
CP0576851
|
(4R)-1-morpholin-4-yl-4-[(1S,2R,13S,14S,17R,18R)-2,9,9,18-tetramethyl-7-propanoyl-5,7-diazapentacyclo[11.7.0.02,10.04,8.014,18]icosa-4(8),5,10-trien-17-yl]pentan-1-one
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|
C34H51N3O3
|
1
|
| 1 |
EC50 = 650 nM
|
|
|
|
CP0576852
|
(4R)-4-[(1S,2R,12R,13S,14S,17R,18R)-12-hydroxy-2,9,9,18-tetramethyl-7-(2-methylpropanoyl)-5,7-diazapentacyclo[11.7.0.02,10.04,8.014,18]icosa-4(8),5,10-trien-17-yl]-1-morpholin-4-ylpentan-1-one
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|
C35H53N3O4
|
1
|
| 1 |
EC50 = 730 nM
|
|
|
|
CP0573077
|
(4R)-1-morpholin-4-yl-4-[(1S,2R,13S,14S,17R,18R)-2,9,9,18-tetramethyl-7-(2-methylprop-2-enoyl)-5,7-diazapentacyclo[11.7.0.02,10.04,8.014,18]icosa-4(8),5,10-trien-17-yl]pentan-1-one
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|
C35H51N3O3
|
1
|
| 1 |
EC50 = 760 nM
|
|
|
|
CP0568861
|
(4R)-4-[(1S,2R,13S,14S,17R,18R)-7-acetyl-2,9,9,18-tetramethyl-6,7-diazapentacyclo[11.7.0.02,10.04,8.014,18]icosa-4(8),5,10-trien-17-yl]-N-methylpentanamide
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|
C30H45N3O2
|
1
|
| 1 |
EC50 = 820 nM
|
|
|
|
CP0577333
|
(4R)-1-morpholin-4-yl-4-[(1S,2R,13S,14S,17R,18R)-2,9,9,18-tetramethyl-5-thia-6,7-diazapentacyclo[11.7.0.02,10.04,8.014,18]icosa-4(8),6,10-trien-17-yl]pentan-1-one
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|
C30H45N3O2S
|
1
|
| 1 |
EC50 = 830 nM
|
|
|
|
CP0550510
|
(5R)-5-[(1S,2R,13S,14S,17R,18R)-7-acetyl-2,9,9,18-tetramethyl-5,7-diazapentacyclo[11.7.0.02,10.04,8.014,18]icosa-4(8),5,10-trien-17-yl]-1-morpholin-4-ylhexan-1-one
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|
C34H51N3O3
|
1
|
| 1 |
EC50 = 980 nM
|
|
|
|
CP0578373
|
(6R)-6-[(1S,2R,13S,14S,17R,18R)-7-acetyl-2,9,9,18-tetramethyl-5,7-diazapentacyclo[11.7.0.02,10.04,8.014,18]icosa-4(8),5,10-trien-17-yl]-1-morpholin-4-ylheptan-1-one
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|
C35H53N3O3
|
1
|
| 1 |
EC50 = 1090 nM
|
|
|
|
CP0580232
|
(4R)-4-[(1S,2R,13S,14S,17R,18R)-7-acetyl-2,9,9,18-tetramethyl-6,7-diazapentacyclo[11.7.0.02,10.04,8.014,18]icosa-4(8),5,10-trien-17-yl]-1-piperidin-1-ylpentan-1-one
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|
C34H51N3O2
|
1
|
| 1 |
EC50 = 1260 nM
|
|
|
|
CP0577940
|
(4R)-4-[(1S,2R,13S,14S,17R,18R)-7-acetyl-2,9,9,18-tetramethyl-6,7-diazapentacyclo[11.7.0.02,10.04,8.014,18]icosa-4(8),5,10-trien-17-yl]-N-ethylpentanamide
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|
C31H47N3O2
|
1
|
| 1 |
EC50 = 1630 nM
|
|
|
|
CP0579932
|
ethyl (1S,2R,13S,14S,17R,18R)-2,9,9,18-tetramethyl-17-[(2R)-5-morpholin-4-yl-5-oxopentan-2-yl]-7-oxa-6-azapentacyclo[11.7.0.02,10.04,8.014,18]icosa-4(8),5,10-triene-5-carboxylate
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|
C34H50N2O5
|
1
|
| 1 |
EC50 = 1840 nM
|
|
|
|
CP0576848
|
(4R)-4-[(1S,2R,13S,14S,17R,18R)-7-acetyl-2,9,9,18-tetramethyl-6,7-diazapentacyclo[11.7.0.02,10.04,8.014,18]icosa-4(8),5,10-trien-17-yl]-N-propylpentanamide
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|
C32H49N3O2
|
1
|
| 1 |
EC50 = 2030 nM
|
|
|
|
CP0570171
|
(4R)-4-[(1S,2R,13S,14S,17R,18R)-7-acetyl-2,9,9,18-tetramethyl-6,7-diazapentacyclo[11.7.0.02,10.04,8.014,18]icosa-4(8),5,10-trien-17-yl]pentanoic acid
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|
C29H42N2O3
|
1
|
| 1 |
EC50 = 2660 nM
|
|
|
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CP0577332
|
(4R)-4-[(1S,2R,13S,14S,17R,18R)-7-acetyl-2,9,9,18-tetramethyl-6,7-diazapentacyclo[11.7.0.02,10.04,8.014,18]icosa-4(8),5,10-trien-17-yl]-N-(2-morpholin-4-ylethyl)pentanamide
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|
C35H54N4O3
|
1
|
| 1 |
EC50 = 2730 nM
|
|
|
|
CP0564307
|
(4R)-4-[(1S,2R,13S,14S,17R,18R)-2,6,9,9,18-pentamethyl-7-thia-5-azapentacyclo[11.7.0.02,10.04,8.014,18]icosa-4(8),5,10-trien-17-yl]pentanoic acid
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|
C28H41NO2S
|
1
|
| 1 |
EC50 = 3370 nM
|
|
|
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CP0260331
|
(4R)-4-[(1S,2R,13S,14S,17R,18R)-2,9,9,18-tetramethyl-6,7-diazapentacyclo[11.7.0.02,10.04,8.014,18]icosa-4(8),5,10-trien-17-yl]pentanoic acid
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|
C27H40N2O2
|
1
|
| 1 |
EC50 = 3990 nM
|
|
|
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CP0550508
|
(4R)-4-[(1S,2R,13S,14S,17R,18R)-7-acetyl-2,9,9,18-tetramethyl-6,7-diazapentacyclo[11.7.0.02,10.04,8.014,18]icosa-4(8),5,10-trien-17-yl]-N-(2-methylphenyl)pentanamide
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|
C36H49N3O2
|
1
|
| 1 |
EC50 = 4470 nM
|
|
|
|
CP0570524
|
(4R)-4-[(1S,2R,13S,14S,17R,18R)-7-acetyl-2,9,9,18-tetramethyl-6,7-diazapentacyclo[11.7.0.02,10.04,8.014,18]icosa-4(8),5,10-trien-17-yl]-N-(5-nitro-1,3-thiazol-2-yl)pentanamide
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|
C32H43N5O4S
|
1
|
| 1 |
EC50 = 4800 nM
|
|
|
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CP0578414
|
(4R)-4-[(1S,2R,13S,14S,17R,18R)-6-amino-2,9,9,18-tetramethyl-7-thia-5-azapentacyclo[11.7.0.02,10.04,8.014,18]icosa-4(8),5,10-trien-17-yl]pentanoic acid
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|
C27H40N2O2S
|
1
|
| 1 |
EC50 = 4940 nM
|
|
|
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CP0149977
|
(4R)-4-[(1R,2S,5R,6R,9S,10S)-1,5,14,14-tetramethyl-16,19-diazapentacyclo[11.8.0.02,10.05,9.015,20]henicosa-12,15,17,19-tetraen-6-yl]pentanoic acid
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|
C28H40N2O2
|
1
|
| 1 |
EC50 = 5020 nM
|
|
|
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CP0576379
|
(4R)-4-[(1S,2R,13S,14S,17R,18R)-7-acetyl-2,9,9,18-tetramethyl-6,7-diazapentacyclo[11.7.0.02,10.04,8.014,18]icosa-4(8),5,10-trien-17-yl]-N-(4-methylphenyl)pentanamide
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|
C36H49N3O2
|
1
|
| 1 |
EC50 = 5410 nM
|
|
|
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CP0577130
|
(4R)-4-[(1S,2R,13S,14S,17R,18R)-2,9,9,18-tetramethyl-6-oxa-5,7-diazapentacyclo[11.7.0.02,10.04,8.014,18]icosa-4,7,10-trien-17-yl]pentanoic acid
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|
C26H38N2O3
|
1
|
| 1 |
EC50 = 5810 nM
|
|
|
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CP0547274
|
(4R)-4-[(1S,2R,12R,13S,14S,17R,18R)-7-acetyl-12-hydroxy-2,9,9,18-tetramethyl-5,7-diazapentacyclo[11.7.0.02,10.04,8.014,18]icosa-4(8),5,10-trien-17-yl]-1-morpholin-4-ylpentan-1-one
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|
C33H49N3O4
|
1
|
| 1 |
EC50 = 8160 nM
|
|
|
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CP0568377
|
(4R)-4-[(1R,2S,5R,6R,9S,10S)-17-amino-1,5,14,14-tetramethyl-16,18-diazapentacyclo[11.8.0.02,10.05,9.015,20]henicosa-12,15,17,19-tetraen-6-yl]-1-morpholin-4-ylpentan-1-one
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|
C32H48N4O2
|
1
|
| 1 |
EC50 = 8250 nM
|
|
|
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CP0077533
|
(4R)-4-[(1S,2R,13S,14S,17R,18R)-2,9,9,18-tetramethyl-7-phenyl-6,7-diazapentacyclo[11.7.0.02,10.04,8.014,18]icosa-4(8),5,10-trien-17-yl]pentanoic acid
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|
C33H44N2O2
|
1
|
| 1 |
EC50 = 8800 nM
|
|
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CP0568376
|
(4R)-4-[(1S,2R,13S,14S,17R,18R)-7-acetyl-2,9,9,18-tetramethyl-6,7-diazapentacyclo[11.7.0.02,10.04,8.014,18]icosa-4(8),5,10-trien-17-yl]-N-(5-methyl-1,3-thiazol-2-yl)pentanamide
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|
C33H46N4O2S
|
1
|
| 1 |
EC50 = 12580 nM
|
|
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CP0580192
|
(4R)-1-morpholin-4-yl-4-[(1S,2R,13S,14S,17R,18R)-2,6,9,9,18-pentamethyl-7-oxa-5-azapentacyclo[11.7.0.02,10.04,8.014,18]icosa-4(8),5,10-trien-17-yl]pentan-1-one
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|
C32H48N2O3
|
1
|
| 1 |
EC50 = 28080 nM
|
|
|
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CP0578372
|
(4R)-4-[(1S,2R,13S,14S,17R,18R)-7-acetyl-2,9,9,18-tetramethyl-6,7-diazapentacyclo[11.7.0.02,10.04,8.014,18]icosa-4(8),5,10-trien-17-yl]-N-(1,3-benzothiazol-2-yl)pentanamide
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|
C36H46N4O2S
|
1
|
| 1 |
EC50 = 31360 nM
|
|
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CP0573076
|
(4R)-4-[(1S,2R,13S,14S,17R,18R)-7-acetyl-2,9,9,18-tetramethyl-6,7-diazapentacyclo[11.7.0.02,10.04,8.014,18]icosa-4(8),5,10-trien-17-yl]-N-(4-methyl-1,3-benzothiazol-2-yl)pentanamide
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|
C37H48N4O2S
|
1
|
| 1 |
EC50 = 43880 nM
|
|
|
