General Information of the Cell Line
Cell Line ID
CL000939
Cell Line Name
CHO-A1
Category
Spontaneously immortalized cell line
Organism
Cricetulus griseus (Chinese hamster)
Cellosaurus ID
CVCL_0214
Tissue Information
Ovary
Disease None
Map of Molecular Bioactivity Related to the Cell Line
Map of Molecular Bioactivity Related to the Cell Line

Cell Line
Protein
Compound

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Cell Line
Protein ID: PT00840, Adenosine receptor A1
Compound ID Compound Name Compound Formula
CP0400722
N-(4-bromophenyl)-2-[4-(2,4-dioxo-3-propyl-1,5-dihydropyrrolo[3,2-d]pyrimidin-6-yl)phenoxy]acetamide
   Show/Hide
C23H21BrN4O4
 1
1
Ki = 1.738 nM
   TI
   LI
   LO
   TS
CP0490177
8-Cyclopentyl-1,3-diethyl-3,7-dihydro-purine-2,6-dione
   Show/Hide
C14H20N4O2
 1
1
Ki = 2.2 nM
   TI
   LI
   LO
   TS
CP0058033
1,3-dipropyl-8-cyclopentylxanthine
   Show/Hide
C16H24N4O2
 1
1
Ki = 3.2 nM
   TI
   LI
   LO
   TS
CP0095850
3-(6-(piperidin-1-yl)-9H-purin-2-yl)phenol
   Show/Hide
C16H17N5O
 1
1
Ki = 10 nM
   TI
   LI
   LO
   TS
CP0382970
4-(6-piperidin-1-yl-7H-purin-2-yl)phenol
   Show/Hide
C16H17N5O
 1
1
Ki = 10 nM
   TI
   LI
   LO
   TS
CP0400111
3-Benzyl-9-phenyl-1-pyridin-4-yl-pyrazolo[1',5':1,6]pyrimido[4,5-d]pyridazin-4(3H)-one
   Show/Hide
C26H18N6O
 1
1
Ki = 10.2 nM
   TI
   LI
   LO
   TS
CP0400110
3-Benzyl-9-phenyl-1-pyridin-3-yl-pyrazolo[1',5':1,6]pyrimido[4,5-d]pyridazin-4(3H)-one
   Show/Hide
C26H18N6O
 1
1
Ki = 11.4 nM
   TI
   LI
   LO
   TS
CP0384049
propan-2-yl 4-(furan-2-yl)-2-methyl-1,4-dihydropyrimido[1,2-a]benzimidazole-3-carboxylate
   Show/Hide
C19H19N3O3
 1
1
Ki = 20 nM
   TI
   LI
   LO
   TS
CP0506363
3-Benzyl-9-phenyl-6-n-propyl-1-pyridin-4-yl-pyrazolo[1',5':1,6]pyrimido-[4,5-d]pyridazin-4(3H)-one
   Show/Hide
C29H24N6O
 1
1
Ki = 28.3 nM
   TI
   LI
   LO
   TS
CP0398033
3-Benzyl-6-methyl-9-phenyl-1-pyridin-4-yl-pyrazolo[1',5':1,6]pyrimido-[4,5-d]pyridazin-4(3H)-one
   Show/Hide
C27H20N6O
 1
1
Ki = 43.6 nM
   TI
   LI
   LO
   TS
CP0425789
3-Benzyl-6-methyl-9-phenyl-1-pyridin-3-yl-pyrazolo[1',5':1,6]pyrimido-[4,5-d]pyridazin-4(3H)-one
   Show/Hide
C27H20N6O
 1
1
Ki = 47.4 nM
   TI
   LI
   LO
   TS
CP0416892
2-(3-chlorophenyl)-6-piperidin-1-yl-7H-purine
   Show/Hide
C16H16ClN5
 1
1
Ki = 50.12 nM
   TI
   LI
   LO
   TS
CP0425788
3-Benzyl-6-ethyl-9-phenyl-1-pyridin-4-yl-pyrazolo[1',5':1,6]pyrimido-[4,5-d]pyridazin-4(3H)-one
   Show/Hide
C28H22N6O
 1
1
Ki = 71.8 nM
   TI
   LI
   LO
   TS
CP0469056
2-[4-(2,4-dioxo-3-propyl-1,5-dihydropyrrolo[3,2-d]pyrimidin-6-yl)phenoxy]-N-(4-fluorophenyl)acetamide
   Show/Hide
C23H21FN4O4
 1
1
Ki = 75.86 nM
   TI
   LI
   LO
   TS
CP0517614
2-(3-chlorophenyl)-6-(4-methylpiperazin-1-yl)-7H-purine
   Show/Hide
C16H17ClN6
 1
1
Ki = 79.43 nM
   TI
   LI
   LO
   TS
CP0501289
3-Benzyl-1-methyl-9-thiophen-3-yl-pyrazolo[1',5':1,6]pyrimido[4,5-d]pyridazin-4(3H)-one
   Show/Hide
C20H15N5OS
 1
1
Ki = 85.3 nM
   TI
   LI
   LO
   TS
CP0425787
3-Benzyl-1-(3-fluorophenyl)-9-phenylpyrazolo[1',5':1,6]pyrimido[4,5-d]pyridazin-4(3H)-one
   Show/Hide
C27H18FN5O
 1
1
Ki = 92.7 nM
   TI
   LI
   LO
   TS
CP0110313
3-benzyl-1-methyl-9-phenylpyrazolo[1',5':1,6]pyrimido[4,5-d]pyridazin-4(3H)-one
   Show/Hide
C22H17N5O
 1
1
Ki = 104.3 nM
   TI
   LI
   LO
   TS
CP0504488
3-Benzyl-1-(4-fluorophenyl)-9-thiophen-3-yl-pyrazolo[1',5':1,6]pyrimido[4,5-d]pyridazin-4(3H)-one
   Show/Hide
C25H16FN5OS
 1
1
Ki = 122.9 nM
   TI
   LI
   LO
   TS
CP0491842
2-(4-chlorophenyl)-6-piperidin-1-yl-7H-purine
   Show/Hide
C16H16ClN5
 1
1
Ki = 125.89 nM
   TI
   LI
   LO
   TS
CP0470575
3-[6-(4-methylpiperazin-1-yl)-7H-purin-2-yl]phenol
   Show/Hide
C16H18N6O
 1
1
Ki = 158.49 nM
   TI
   LI
   LO
   TS
CP0387105
3-Benzyl-6-ethyl-9-phenyl-1-pyridin-3-yl-pyrazolo[1',5':1,6]pyrimido-[4,5-d]pyridazin-4(3H)-one
   Show/Hide
C28H22N6O
 1
1
Ki = 180.2 nM
   TI
   LI
   LO
   TS
CP0385545
6-[4-[[3-(4-bromophenyl)-1,2,4-oxadiazol-5-yl]methoxy]-2-methoxyphenyl]-1,3-dimethyl-5H-pyrrolo[3,2-d]pyrimidine-2,4-dione
   Show/Hide
C24H20BrN5O5
 1
1
Ki = 181.97 nM
   TI
   LI
   LO
   TS
CP0469640
3-Benzyl-1-(3-fluorophenyl)-9-thiophen-3-yl-pyrazolo [1',5':1,6]pyrimido[4,5-d]pyridazin-4(3H)-one
   Show/Hide
C25H16FN5OS
 1
1
Ki = 188.5 nM
   TI
   LI
   LO
   TS
CP0387103
3-Benzyl-6-isopropyl-9-phenyl-1-pyridin-4-yl-pyrazolo[1',5':1,6]pyrimido-[4,5-d]pyridazin-4(3H)-one
   Show/Hide
C29H24N6O
 1
1
Ki = 192.3 nM
   TI
   LI
   LO
   TS
CP0496603
3-Benzyl-1-(4-fluorophenyl)-9-phenylpyrazolo[1',5':1,6]pyrimido[4,5-d]pyridazin-4(3H)-one
   Show/Hide
C27H18FN5O
 1
1
Ki = 252.3 nM
   TI
   LI
   LO
   TS
CP0469641
3-Benzyl-6-methyl-9-phenyl-1-pyridin-4-ylpyrazolo[1',5':1,6]pyrimido[4,5-d]pyridazin-4(3H)-thione
   Show/Hide
C27H20N6S
 1
1
Ki = 267.4 nM
   TI
   LI
   LO
   TS
CP0517613
2-(4-chlorophenyl)-6-(4-methylpiperazin-1-yl)-7H-purine
   Show/Hide
C16H17ClN6
 1
1
Ki = 398.11 nM
   TI
   LI
   LO
   TS
CP0548247
4-[6-(4-methylpiperazin-1-yl)-7H-purin-2-yl]phenol
   Show/Hide
C16H18N6O
 1
1
Ki = 398.11 nM
   TI
   LI
   LO
   TS
CP0435312
1-Methyl-9-phenyl-3-(1-phenylethyl)pyrazolo[1',5':1,6]pyrimido-[4,5-d]pyridazin-4(3H)-one
   Show/Hide
C23H19N5O
 1
1
Ki = 475.2 nM
   TI
   LI
   LO
   TS
CP0493461
3-Benzyl-1,9-diphenyl-6-n-propylpyrazolo[1',5':1,6]pyrimido[4,5-d]pyridazin-4(3H)-one
   Show/Hide
C30H25N5O
 1
1
Ki = 563.5 nM
   TI
   LI
   LO
   TS
CP0412117
2-(3,4-dichlorophenyl)-6-(4-methylpiperazin-1-yl)-7H-purine
   Show/Hide
C16H16Cl2N6
 1
1
Ki = 630.96 nM
   TI
   LI
   LO
   TS
CP0530269
2-[9-methyl-6-(4-methylpiperazin-1-yl)purin-2-yl]phenol
   Show/Hide
C17H20N6O
 1
1
Ki = 630.96 nM
   TI
   LI
   LO
   TS
CP0053494
4-(2-{[5-amino-2-(furan-2-yl)-[1,2,4]triazolo[1,5-a][1,3,5]triazin-7-yl]amino}ethyl)phenol
   Show/Hide
C16H15N7O2
 1
1
Ki = 683 nM
   TI
   LI
   LO
   TS
CP0435310
3-Benzyl-1,9-diphenylpyrazolo[1',5':1,6]pyrimido[4,5-d]pyridazin-4(3H)-one
   Show/Hide
C27H19N5O
 1
1
Ki = 1432 nM
   TI
   LI
   LO
   TS
CP0425786
3-Benzyl-1,9-diphenyl-6-methylpyrazolo[1',5':1,6]pyrimido[4,5-d]pyridazin-4(3H)-one
   Show/Hide
C28H21N5O
 1
1
Ki = 1595 nM
   TI
   LI
   LO
   TS
CP0479120
3-Benzyl-1-chloro-6-methyl-9-phenylpyrazolo[1',5':1,6]pyrimido[4,5-d]pyridazin-4(3H)-one
   Show/Hide
C22H16ClN5O
 1
1
Ki = 1616 nM
   TI
   LI
   LO
   TS
CP0425785
6-Ethyl-9-phenyl-3-(1-phenylethyl)-1-methylpyrazolo[1',5':1,6]pyrimido-[4,5-d]pyridazin-4(3H)-one
   Show/Hide
C25H23N5O
 1
1
Ki = 2385 nM
   TI
   LI
   LO
   TS
CP0469639
3-Benzyl-1,9-diphenyl-6-ethylpyrazolo[1',5':1,6]pyrimido[4,5-d]pyridazin-4(3H)-one
   Show/Hide
C29H23N5O
 1
1
Ki = 2445 nM
   TI
   LI
   LO
   TS
CP0382971
2-(2,5-dichlorophenyl)-6-(4-methylpiperazin-1-yl)-7H-purine
   Show/Hide
C16H16Cl2N6
 1
1
Ki = 2511.89 nM
   TI
   LI
   LO
   TS
CP0425791
1,6-Dimethyl-9-phenyl-3-(1-phenylethyl)pyrazolo[1',5':1,6]pyrimido-[4,5-d]pyridazin-4(3H)-one
   Show/Hide
C24H21N5O
 1
1
Ki = 3080 nM
   TI
   LI
   LO
   TS
CP0387104
3-Benzyl-1-(3-fluorophenyl)-6-methyl-9-phenylpyrazolo[1',5':1,6]pyrimido[4,5d]pyridazin-4(3H)-one
   Show/Hide
C28H20FN5O
 1
1
Ki = 3245 nM
   TI
   LI
   LO
   TS
CP0058557
7-Benzyl-4,9-dimethyl-2-phenyl-7H-3,3a,5,7,8-pentaaza-cyclopenta[a]naphthalen-6-one
   Show/Hide
C23H19N5O
 1
1
Ki = 3250 nM
   TI
   LI
   LO
   TS
Protein family and CMB statistics Related to the Cell Line
Cell Lines Derived from the same Tissue Source (Ovary)
Cell Line Name Organism Disease
SW626 Homo sapiens (Human) Colon adenocarcinoma
FU-OV-1 Homo sapiens (Human) High grade ovarian serous adenocarcinoma
TOV-21G Homo sapiens (Human) Ovarian clear cell adenocarcinoma
ES-2 Homo sapiens (Human) Ovarian clear cell adenocarcinoma
A2780 Homo sapiens (Human) Ovarian endometrioid adenocarcinoma
A2780ADR Homo sapiens (Human) Ovarian endometrioid adenocarcinoma
IGROV-1 Homo sapiens (Human) Ovarian endometrioid adenocarcinoma
CHO Cricetulus griseus (Chinese hamster) -
CHO-K1 Cricetulus griseus (Chinese hamster) -
CHO/Galpha16 Cricetulus griseus (Chinese hamster) -
CHOP Cricetulus griseus (Chinese hamster) -
T-REx-CHO Cricetulus griseus (Chinese hamster) -
CHO Pro-4 MtxRII OuaR-2-4 Cricetulus griseus (Chinese hamster) -
Flp-In-CHO Cricetulus griseus (Chinese hamster) -
CHO-DXB11 Cricetulus griseus (Chinese hamster) -
CHO-CPR C10 Cricetulus griseus (Chinese hamster) -
PathHunter CHO-K1 EDG1 beta-arrestin Cricetulus griseus (Chinese hamster) -
CHO-S Cricetulus griseus (Chinese hamster) -
CHO-7 Cricetulus griseus (Chinese hamster) -
CHO-T Cricetulus griseus (Chinese hamster) -
ValiScreen human CRTH2 Cricetulus griseus (Chinese hamster) -
PathHunter CHO-K1 GLP1R beta-arrestin-1 Cricetulus griseus (Chinese hamster) -
CHO-K1/CRE-Luc Cricetulus griseus (Chinese hamster) -
CHO-hTRPV1 Cricetulus griseus (Chinese hamster) -
Lec1 Cricetulus griseus (Chinese hamster) -
CHO-N9 Cricetulus griseus (Chinese hamster) -
CHO/IR Cricetulus griseus (Chinese hamster) -
CHO-K1/Gqi5 Cricetulus griseus (Chinese hamster) -
CHO-K9 Cricetulus griseus (Chinese hamster) -
CHO-A12 Cricetulus griseus (Chinese hamster) -
CHO E1a Cricetulus griseus (Chinese hamster) -
PathHunter CHO-K1 CXCR7 beta-arrestin Cricetulus griseus (Chinese hamster) -
R2/PCFT4 Cricetulus griseus (Chinese hamster) -
Chinese hamster RT16 Cricetulus griseus (Chinese hamster) -
CHO-D-/aequorin Cricetulus griseus (Chinese hamster) -
CHO-DUKX-A2 Cricetulus griseus (Chinese hamster) -
Lec3.2.8.1 Cricetulus griseus (Chinese hamster) -
CellSensor NFAT-bla CHO-K1 Cricetulus griseus (Chinese hamster) -
Chinese hamster PC43-10 Cricetulus griseus (Chinese hamster) -
CHO-A3 Cricetulus griseus (Chinese hamster) -
CHO/VR1 Cricetulus griseus (Chinese hamster) -
CHO-hgamma Cricetulus griseus (Chinese hamster) -
CHO-1 Cricetulus griseus (Chinese hamster) -
CHO-03 Cricetulus griseus (Chinese hamster) -
CHO CGE Cricetulus griseus (Chinese hamster) -
CHO-CHRM2 Cricetulus griseus (Chinese hamster) -
CHO CRE-SPAP Cricetulus griseus (Chinese hamster) -
CHO 2B7 Cricetulus griseus (Chinese hamster) -
hMORCHO Cricetulus griseus (Chinese hamster) -
CHO Pro-5 Cricetulus griseus (Chinese hamster) -
CHO CCR3/2 Cricetulus griseus (Chinese hamster) -
PPLS-HA-GPR88 CHO Cricetulus griseus (Chinese hamster) -
hTRPV4/CHO Cricetulus griseus (Chinese hamster) -
CHO 1827 Cricetulus griseus (Chinese hamster) -
CHO ducX#98 Cricetulus griseus (Chinese hamster) -
CHO 1829 Cricetulus griseus (Chinese hamster) -
CHO-mtAEQ Cricetulus griseus (Chinese hamster) -
DHB-11 CHO Cricetulus griseus (Chinese hamster) -
CellSensor CRE-bla CHO-K1 Cricetulus griseus (Chinese hamster) -
PathHunter CHO-K1 GLP1R beta-arrestin-2 Cricetulus griseus (Chinese hamster) -
Sf21 Spodoptera frugiperda (Fall armyworm) -
Sf9 Spodoptera frugiperda (Fall armyworm) -
SF-12 Spodoptera frugiperda (Fall armyworm) -
Tni PRO Trichoplusia ni (Cabbage looper) -