General Information of the Cell Line
Cell Line ID
CL000377
Cell Line Name
ES-2
Synonyms
ES2
Category
Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_3509
Tissue Information
Ovary
Disease
Ovarian clear cell adenocarcinoma (NCIt: C40078)
Clear cell adenocarcinoma of the ovary (ORDO: Orphanet_398971)
Map of Molecular Bioactivity Related to the Cell Line
Map of Molecular Bioactivity Related to the Cell Line

Cell Line
Protein
Compound

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Cell Line
Protein ID: PT01820, Aminopeptidase N
Compound ID Compound Name Compound Formula
CP0472906
(2S)-2-[(2-bromophenyl)carbamoylamino]-N-hydroxy-4-methylpentanamide
   Show/Hide
C13H18BrN3O3
 1
1
IC50 = 530 nM
   TI
   LI
   LO
   TS
CP0391667
(2S)-N-hydroxy-4-methyl-2-[(2-methylphenyl)carbamoylamino]pentanamide
   Show/Hide
C14H21N3O3
 1
1
IC50 = 610 nM
   TI
   LI
   LO
   TS
CP0460222
(2S)-2-[(2-chlorophenyl)methylcarbamoylamino]-N-hydroxy-4-methylpentanamide
   Show/Hide
C14H20ClN3O3
 1
1
IC50 = 650 nM
   TI
   LI
   LO
   TS
CP0434043
(2S)-N-hydroxy-2-[(2-methoxyphenyl)carbamoylamino]-4-methylpentanamide
   Show/Hide
C14H21N3O4
 1
1
IC50 = 700 nM
   TI
   LI
   LO
   TS
CP0565803
(2S)-2-[(2-bromophenyl)methylcarbamoylamino]-N-hydroxy-4-methylpentanamide
   Show/Hide
C14H20BrN3O3
 1
1
IC50 = 730 nM
   TI
   LI
   LO
   TS
CP0393151
(2S)-N-hydroxy-4-methyl-2-[[1-[(2-phenylmethoxyphenyl)methyl]triazol-4-yl]methylcarbamoylamino]pentanamide
   Show/Hide
C24H30N6O4
 1
1
IC50 = 740 nM
   TI
   LI
   LO
   TS
CP0424085
(2S)-N-hydroxy-4-methyl-2-[[1-[(3-phenylmethoxyphenyl)methyl]triazol-4-yl]methylcarbamoylamino]pentanamide
   Show/Hide
C24H30N6O4
 1
1
IC50 = 870 nM
   TI
   LI
   LO
   TS
CP0515615
(2S)-2-[(2-chlorophenyl)carbamoylamino]-N-hydroxy-4-methylpentanamide
   Show/Hide
C13H18ClN3O3
 1
1
IC50 = 1310 nM
   TI
   LI
   LO
   TS
CP0566687
(2S)-2-[[1-[(2-ethoxyphenyl)methyl]triazol-4-yl]methylcarbamoylamino]-N-hydroxy-4-methylpentanamide
   Show/Hide
C19H28N6O4
 1
1
IC50 = 2100 nM
   TI
   LI
   LO
   TS
CP0508627
2-(5'-chloro-2'-oxospiro[1,3-dioxepane-2,3'-indole]-1'-yl)-N-hydroxyacetamide
   Show/Hide
C14H15ClN2O5
 1
1
IC50 = 3120 nM
   TI
   LI
   LO
   TS
CP0424086
(2S)-N-hydroxy-2-[[1-[1-(2-methoxyphenyl)ethyl]triazol-4-yl]methylcarbamoylamino]-4-methylpentanamide
   Show/Hide
C19H28N6O4
 1
1
IC50 = 4800 nM
   TI
   LI
   LO
   TS
CP0560419
(2S)-N-hydroxy-2-[[1-[(2-methoxyphenyl)methyl]triazol-4-yl]methylcarbamoylamino]-4-methylpentanamide
   Show/Hide
C18H26N6O4
 1
1
IC50 = 6500 nM
   TI
   LI
   LO
   TS
CP0472907
(2S)-N-hydroxy-4-methyl-2-[[1-[(2-methylphenyl)methyl]triazol-4-yl]methylcarbamoylamino]pentanamide
   Show/Hide
C18H26N6O3
 1
1
IC50 = 6900 nM
   TI
   LI
   LO
   TS
CP0465631
2-(5'-chloro-2'-oxospiro[1,3-dioxolane-2,3'-indole]-1'-yl)-N-hydroxyacetamide
   Show/Hide
C12H11ClN2O5
 1
1
IC50 = 9580 nM
   TI
   LI
   LO
   TS
CP0539480
2-(5'-chloro-2'-oxospiro[1,3-dioxane-2,3'-indole]-1'-yl)-N-hydroxyacetamide
   Show/Hide
C13H13ClN2O5
 1
1
IC50 = 10940 nM
   TI
   LI
   LO
   TS
CP0444009
2-(5'-bromo-2'-oxospiro[1,3-dioxepane-2,3'-indole]-1'-yl)-N-hydroxyacetamide
   Show/Hide
C14H15BrN2O5
 1
1
IC50 = 12100 nM
   TI
   LI
   LO
   TS
CP0413707
2-(5'-bromo-2'-oxospiro[1,3-dioxolane-2,3'-indole]-1'-yl)-N-hydroxyacetamide
   Show/Hide
C12H11BrN2O5
 1
1
IC50 = 12400 nM
   TI
   LI
   LO
   TS
CP0539346
2-(5'-fluoro-2'-oxospiro[1,3-dioxepane-2,3'-indole]-1'-yl)-N-hydroxyacetamide
   Show/Hide
C14H15FN2O5
 1
1
IC50 = 15160 nM
   TI
   LI
   LO
   TS
CP0558459
2-(5'-fluoro-2'-oxospiro[1,3-dioxolane-2,3'-indole]-1'-yl)-N-hydroxyacetamide
   Show/Hide
C12H11FN2O5
 1
1
IC50 = 16190 nM
   TI
   LI
   LO
   TS
CP0539348
2-(5'-bromo-2'-oxospiro[1,3-dioxane-2,3'-indole]-1'-yl)-N-hydroxyacetamide
   Show/Hide
C13H13BrN2O5
 1
1
IC50 = 19660 nM
   TI
   LI
   LO
   TS
CP0037780
(2S)-2-[(2S,3R)-3-amino-2-hydroxy-4-phenylbutanamido]-4-methylpentanoic acid
   Show/Hide
C16H24N2O4
 3
1
IC50 = 20120 nM
   TI
   LI
   LO
   TS
2
IC50 = 29670 nM
   TI
   LI
   LO
   TS
3
IC50 = 35500 nM
   TI
   LI
   LO
   TS
CP0527484
2-(5'-fluoro-2'-oxospiro[1,3-dioxane-2,3'-indole]-1'-yl)-N-hydroxyacetamide
   Show/Hide
C13H13FN2O5
 1
1
IC50 = 97490 nM
   TI
   LI
   LO
   TS
Protein family and CMB statistics Related to the Cell Line
Cell Lines Derived from the same Tissue Source (Ovary)
Cell Line Name Organism Disease
SW626 Homo sapiens (Human) Colon adenocarcinoma
FU-OV-1 Homo sapiens (Human) High grade ovarian serous adenocarcinoma
TOV-21G Homo sapiens (Human) Ovarian clear cell adenocarcinoma
A2780 Homo sapiens (Human) Ovarian endometrioid adenocarcinoma
A2780ADR Homo sapiens (Human) Ovarian endometrioid adenocarcinoma
IGROV-1 Homo sapiens (Human) Ovarian endometrioid adenocarcinoma
CHO Cricetulus griseus (Chinese hamster) -
CHO-K1 Cricetulus griseus (Chinese hamster) -
CHO/Galpha16 Cricetulus griseus (Chinese hamster) -
CHOP Cricetulus griseus (Chinese hamster) -
T-REx-CHO Cricetulus griseus (Chinese hamster) -
CHO Pro-4 MtxRII OuaR-2-4 Cricetulus griseus (Chinese hamster) -
Flp-In-CHO Cricetulus griseus (Chinese hamster) -
CHO-DXB11 Cricetulus griseus (Chinese hamster) -
CHO-CPR C10 Cricetulus griseus (Chinese hamster) -
PathHunter CHO-K1 EDG1 beta-arrestin Cricetulus griseus (Chinese hamster) -
CHO-S Cricetulus griseus (Chinese hamster) -
CHO-7 Cricetulus griseus (Chinese hamster) -
CHO-T Cricetulus griseus (Chinese hamster) -
ValiScreen human CRTH2 Cricetulus griseus (Chinese hamster) -
PathHunter CHO-K1 GLP1R beta-arrestin-1 Cricetulus griseus (Chinese hamster) -
CHO-K1/CRE-Luc Cricetulus griseus (Chinese hamster) -
CHO-hTRPV1 Cricetulus griseus (Chinese hamster) -
Lec1 Cricetulus griseus (Chinese hamster) -
CHO-N9 Cricetulus griseus (Chinese hamster) -
CHO/IR Cricetulus griseus (Chinese hamster) -
CHO-K1/Gqi5 Cricetulus griseus (Chinese hamster) -
CHO-K9 Cricetulus griseus (Chinese hamster) -
CHO-A12 Cricetulus griseus (Chinese hamster) -
CHO E1a Cricetulus griseus (Chinese hamster) -
PathHunter CHO-K1 CXCR7 beta-arrestin Cricetulus griseus (Chinese hamster) -
R2/PCFT4 Cricetulus griseus (Chinese hamster) -
Chinese hamster RT16 Cricetulus griseus (Chinese hamster) -
CHO-A1 Cricetulus griseus (Chinese hamster) -
CHO-D-/aequorin Cricetulus griseus (Chinese hamster) -
CHO-DUKX-A2 Cricetulus griseus (Chinese hamster) -
Lec3.2.8.1 Cricetulus griseus (Chinese hamster) -
CellSensor NFAT-bla CHO-K1 Cricetulus griseus (Chinese hamster) -
Chinese hamster PC43-10 Cricetulus griseus (Chinese hamster) -
CHO-A3 Cricetulus griseus (Chinese hamster) -
CHO/VR1 Cricetulus griseus (Chinese hamster) -
CHO-hgamma Cricetulus griseus (Chinese hamster) -
CHO-1 Cricetulus griseus (Chinese hamster) -
CHO-03 Cricetulus griseus (Chinese hamster) -
CHO CGE Cricetulus griseus (Chinese hamster) -
CHO-CHRM2 Cricetulus griseus (Chinese hamster) -
CHO CRE-SPAP Cricetulus griseus (Chinese hamster) -
CHO 2B7 Cricetulus griseus (Chinese hamster) -
hMORCHO Cricetulus griseus (Chinese hamster) -
CHO Pro-5 Cricetulus griseus (Chinese hamster) -
CHO CCR3/2 Cricetulus griseus (Chinese hamster) -
PPLS-HA-GPR88 CHO Cricetulus griseus (Chinese hamster) -
hTRPV4/CHO Cricetulus griseus (Chinese hamster) -
CHO 1827 Cricetulus griseus (Chinese hamster) -
CHO ducX#98 Cricetulus griseus (Chinese hamster) -
CHO 1829 Cricetulus griseus (Chinese hamster) -
CHO-mtAEQ Cricetulus griseus (Chinese hamster) -
DHB-11 CHO Cricetulus griseus (Chinese hamster) -
CellSensor CRE-bla CHO-K1 Cricetulus griseus (Chinese hamster) -
PathHunter CHO-K1 GLP1R beta-arrestin-2 Cricetulus griseus (Chinese hamster) -
Sf21 Spodoptera frugiperda (Fall armyworm) -
Sf9 Spodoptera frugiperda (Fall armyworm) -
SF-12 Spodoptera frugiperda (Fall armyworm) -
Tni PRO Trichoplusia ni (Cabbage looper) -