General Information of the Cell Line
Cell Line ID
CL000449
Cell Line Name
FU-OV-1
Synonyms
FUOV-1
FUOV1
Fukuoka University-OVarian-1
Category
Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_2047
Tissue Information
Ovary
Disease
High grade ovarian serous adenocarcinoma (NCIt: C105555)
Map of Molecular Bioactivity Related to the Cell Line
Map of Molecular Bioactivity Related to the Cell Line

Cell Line
Protein
Compound

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Cell Line
Protein ID: PT01427, Myt1 kinase
Compound ID Compound Name Compound Formula
CP0574500
2-amino-5-cyclopropyl-1-(3-hydroxy-2,6-dimethylphenyl)pyrrolo[2,3-b]pyridine-3-carboxamide
   Show/Hide
C19H20N4O2
 1
1
IC50 = 5 nM
   TI
   LI
   LO
   TS
CP0570320
2-amino-5-chloro-1-(3-hydroxy-2,6-dimethylphenyl)-6-methylpyrrolo[2,3-b]pyridine-3-carboxamide
   Show/Hide
C17H17ClN4O2
 1
1
IC50 = 7 nM
   TI
   LI
   LO
   TS
CP0574498
2-amino-1-(3-hydroxy-2,6-dimethylphenyl)-5,6-dimethylpyrrolo[2,3-b]pyridine-3-carboxamide
   Show/Hide
C18H20N4O2
 1
1
IC50 = 14 nM
   TI
   LI
   LO
   TS
CP0577047
2-amino-5-chloro-1-(3-hydroxy-2,6-dimethylphenyl)pyrrolo[2,3-b]pyridine-3-carboxamide
   Show/Hide
C16H15ClN4O2
 1
1
IC50 = 17 nM
   TI
   LI
   LO
   TS
CP0546952
2-amino-1-(3-hydroxy-2,6-dimethylphenyl)-5-methylpyrrolo[2,3-b]pyridine-3-carboxamide
   Show/Hide
C17H18N4O2
 1
1
IC50 = 24 nM
   TI
   LI
   LO
   TS
CP0578806
6-amino-5-(3-hydroxy-2,6-dimethylphenyl)-2-morpholin-4-ylpyrrolo[2,3-b]pyrazine-7-carboxamide
   Show/Hide
C19H22N6O3
 1
1
IC50 = 25 nM
   TI
   LI
   LO
   TS
CP0577566
6-amino-5-(3-hydroxy-2,6-dimethylphenyl)-2-(2-hydroxypropan-2-yl)pyrrolo[2,3-b]pyrazine-7-carboxamide
   Show/Hide
C18H21N5O3
 1
1
IC50 = 26 nM
   TI
   LI
   LO
   TS
CP0579127
2-amino-5-cyano-1-(3-hydroxy-2,6-dimethylphenyl)pyrrolo[2,3-b]quinoxaline-3-carboxamide
   Show/Hide
C20H16N6O2
 1
1
IC50 = 34 nM
   TI
   LI
   LO
   TS
CP0580003
6-amino-5-(3-hydroxy-2,6-dimethylphenyl)-2-(1,3-thiazol-2-yl)pyrrolo[2,3-b]pyrazine-7-carboxamide
   Show/Hide
C18H16N6O2S
 1
1
IC50 = 34 nM
   TI
   LI
   LO
   TS
CP0577583
2-amino-8-cyano-1-(3-hydroxy-2,6-dimethylphenyl)pyrrolo[3,2-b]quinoxaline-3-carboxamide
   Show/Hide
C20H16N6O2
 1
1
IC50 = 36 nM
   TI
   LI
   LO
   TS
CP0578487
6-amino-2-cyclopropyl-5-(3-hydroxy-2,6-dimethylphenyl)pyrrolo[2,3-b]pyrazine-7-carboxamide
   Show/Hide
C18H19N5O2
 1
1
IC50 = 42 nM
   TI
   LI
   LO
   TS
CP0579917
6-amino-2-(3,5-difluoropyridin-2-yl)-5-(3-hydroxy-2,6-dimethylphenyl)pyrrolo[2,3-b]pyrazine-7-carboxamide
   Show/Hide
C20H16F2N6O2
 1
1
IC50 = 50 nM
   TI
   LI
   LO
   TS
CP0568557
2-amino-1-(2-chloro-3-hydroxy-6-methylphenyl)pyrrolo[3,2-b]quinoxaline-3-carboxamide
   Show/Hide
C18H14ClN5O2
 1
1
IC50 = 70 nM
   TI
   LI
   LO
   TS
CP0548461
6-amino-5-(3-hydroxy-2,6-dimethylphenyl)-2,3-dimethylpyrrolo[2,3-b]pyrazine-7-carboxamide
   Show/Hide
C17H19N5O2
 1
1
IC50 = 73 nM
   TI
   LI
   LO
   TS
CP0579252
6-amino-5-(3-hydroxy-2,6-dimethylphenyl)-2-methylpyrrolo[2,3-b]pyrazine-7-carboxamide
   Show/Hide
C16H17N5O2
 1
1
IC50 = 108 nM
   TI
   LI
   LO
   TS
CP0548444
2-amino-1-(3-hydroxy-2,6-dimethylphenyl)-8-(2-methylpyrazol-3-yl)pyrrolo[3,2-b]quinoxaline-3-carboxamide
   Show/Hide
C23H21N7O2
 1
1
IC50 = 120 nM
   TI
   LI
   LO
   TS
CP0575859
2-amino-1-(3-hydroxy-2,6-dimethylphenyl)pyrrolo[3,2-b]quinoxaline-3-carboxamide
   Show/Hide
C19H17N5O2
 1
1
IC50 = 130 nM
   TI
   LI
   LO
   TS
CP0579599
2-amino-1-(3-hydroxy-2,6-dimethylphenyl)-6-(2-methylpyrazol-3-yl)pyrrolo[2,3-b]quinoxaline-3-carboxamide
   Show/Hide
C23H21N7O2
 1
1
IC50 = 170 nM
   TI
   LI
   LO
   TS
CP0579262
2-amino-8-bromo-1-(3-hydroxy-2,6-dimethylphenyl)pyrrolo[3,2-b]quinoxaline-3-carboxamide
   Show/Hide
C19H16BrN5O2
 1
1
IC50 = 190 nM
   TI
   LI
   LO
   TS
CP0572964
2-amino-6-cyano-1-(3-hydroxy-2,6-dimethylphenyl)pyrrolo[2,3-b]quinoxaline-3-carboxamide
   Show/Hide
C20H16N6O2
 1
1
IC50 = 200 nM
   TI
   LI
   LO
   TS
CP0571615
2-amino-6-(cyclopenten-1-yl)-1-(3-hydroxy-2,6-dimethylphenyl)pyrrolo[2,3-b]quinoxaline-3-carboxamide
   Show/Hide
C24H23N5O2
 1
1
IC50 = 300 nM
   TI
   LI
   LO
   TS
CP0578486
2-amino-1-(3-hydroxy-2,6-dimethylphenyl)-5-(2-methylpyrazol-3-yl)pyrrolo[2,3-b]quinoxaline-3-carboxamide
   Show/Hide
C23H21N7O2
 1
1
IC50 = 320 nM
   TI
   LI
   LO
   TS
CP0548443
2-amino-1-(5-hydroxy-2-methylphenyl)pyrrolo[2,3-b]quinoline-3-carboxamide
   Show/Hide
C19H16N4O2
 1
1
IC50 = 360 nM
   TI
   LI
   LO
   TS
CP0579021
2-amino-6-bromo-1-(3-hydroxy-2,6-dimethylphenyl)pyrrolo[2,3-b]quinoxaline-3-carboxamide
   Show/Hide
C19H16BrN5O2
 1
1
IC50 = 360 nM
   TI
   LI
   LO
   TS
CP0574495
2-amino-1-(6-chloro-3-hydroxy-2-methylphenyl)pyrrolo[3,2-b]quinoxaline-3-carboxamide
   Show/Hide
C18H14ClN5O2
 1
1
IC50 = 380 nM
   TI
   LI
   LO
   TS
CP0571618
6-amino-5-(3-hydroxy-2,6-dimethylphenyl)-3-methylpyrrolo[2,3-b]pyrazine-7-carboxamide
   Show/Hide
C16H17N5O2
 1
1
IC50 = 488 nM
   TI
   LI
   LO
   TS
CP0548445
2-amino-8-(cyclopenten-1-yl)-1-(3-hydroxy-2,6-dimethylphenyl)pyrrolo[3,2-b]quinoxaline-3-carboxamide
   Show/Hide
C24H23N5O2
 1
1
IC50 = 550 nM
   TI
   LI
   LO
   TS
CP0578803
1-(3-hydroxy-2,6-dimethylphenyl)pyrrolo[3,2-b]quinoxaline-3-carboxamide
   Show/Hide
C19H16N4O2
 1
1
IC50 = 560 nM
   TI
   LI
   LO
   TS
CP0571617
6-amino-5-(3-hydroxy-2,6-dimethylphenyl)pyrrolo[2,3-b]pyrazine-7-carboxamide
   Show/Hide
C15H15N5O2
 1
1
IC50 = 626 nM
   TI
   LI
   LO
   TS
CP0579261
2-amino-1-(2,6-dichloro-3-hydroxyphenyl)pyrrolo[3,2-b]quinoxaline-3-carboxamide
   Show/Hide
C17H11Cl2N5O2
 1
1
IC50 = 920 nM
   TI
   LI
   LO
   TS
CP0577563
2-amino-5-(cyclopenten-1-yl)-1-(3-hydroxy-2,6-dimethylphenyl)pyrrolo[2,3-b]quinoxaline-3-carboxamide
   Show/Hide
C24H23N5O2
 1
1
IC50 = 1050 nM
   TI
   LI
   LO
   TS
CP0579251
2-amino-7-bromo-1-(3-hydroxy-2,6-dimethylphenyl)pyrrolo[3,2-b]quinoxaline-3-carboxamide
   Show/Hide
C19H16BrN5O2
 1
1
IC50 = 1370 nM
   TI
   LI
   LO
   TS
CP0052636
2-amino-1-(5-hydroxy-2-methylphenyl)pyrrolo[3,2-b]quinoxaline-3-carboxamide
   Show/Hide
C18H15N5O2
 1
1
IC50 > 3000 nM
   TI
   LI
   LO
   TS
CP0571614
2-amino-1-(3-hydroxy-2-methylphenyl)pyrrolo[3,2-b]quinoxaline-3-carboxamide
   Show/Hide
C18H15N5O2
 1
1
IC50 > 3000 nM
   TI
   LI
   LO
   TS
Protein family and CMB statistics Related to the Cell Line
Cell Lines Derived from the same Tissue Source (Ovary)
Cell Line Name Organism Disease
SW626 Homo sapiens (Human) Colon adenocarcinoma
TOV-21G Homo sapiens (Human) Ovarian clear cell adenocarcinoma
ES-2 Homo sapiens (Human) Ovarian clear cell adenocarcinoma
A2780 Homo sapiens (Human) Ovarian endometrioid adenocarcinoma
A2780ADR Homo sapiens (Human) Ovarian endometrioid adenocarcinoma
IGROV-1 Homo sapiens (Human) Ovarian endometrioid adenocarcinoma
CHO Cricetulus griseus (Chinese hamster) -
CHO-K1 Cricetulus griseus (Chinese hamster) -
CHO/Galpha16 Cricetulus griseus (Chinese hamster) -
CHOP Cricetulus griseus (Chinese hamster) -
T-REx-CHO Cricetulus griseus (Chinese hamster) -
CHO Pro-4 MtxRII OuaR-2-4 Cricetulus griseus (Chinese hamster) -
Flp-In-CHO Cricetulus griseus (Chinese hamster) -
CHO-DXB11 Cricetulus griseus (Chinese hamster) -
CHO-CPR C10 Cricetulus griseus (Chinese hamster) -
PathHunter CHO-K1 EDG1 beta-arrestin Cricetulus griseus (Chinese hamster) -
CHO-S Cricetulus griseus (Chinese hamster) -
CHO-7 Cricetulus griseus (Chinese hamster) -
CHO-T Cricetulus griseus (Chinese hamster) -
ValiScreen human CRTH2 Cricetulus griseus (Chinese hamster) -
PathHunter CHO-K1 GLP1R beta-arrestin-1 Cricetulus griseus (Chinese hamster) -
CHO-K1/CRE-Luc Cricetulus griseus (Chinese hamster) -
CHO-hTRPV1 Cricetulus griseus (Chinese hamster) -
Lec1 Cricetulus griseus (Chinese hamster) -
CHO-N9 Cricetulus griseus (Chinese hamster) -
CHO/IR Cricetulus griseus (Chinese hamster) -
CHO-K1/Gqi5 Cricetulus griseus (Chinese hamster) -
CHO-K9 Cricetulus griseus (Chinese hamster) -
CHO-A12 Cricetulus griseus (Chinese hamster) -
CHO E1a Cricetulus griseus (Chinese hamster) -
PathHunter CHO-K1 CXCR7 beta-arrestin Cricetulus griseus (Chinese hamster) -
R2/PCFT4 Cricetulus griseus (Chinese hamster) -
Chinese hamster RT16 Cricetulus griseus (Chinese hamster) -
CHO-A1 Cricetulus griseus (Chinese hamster) -
CHO-D-/aequorin Cricetulus griseus (Chinese hamster) -
CHO-DUKX-A2 Cricetulus griseus (Chinese hamster) -
Lec3.2.8.1 Cricetulus griseus (Chinese hamster) -
CellSensor NFAT-bla CHO-K1 Cricetulus griseus (Chinese hamster) -
Chinese hamster PC43-10 Cricetulus griseus (Chinese hamster) -
CHO-A3 Cricetulus griseus (Chinese hamster) -
CHO/VR1 Cricetulus griseus (Chinese hamster) -
CHO-hgamma Cricetulus griseus (Chinese hamster) -
CHO-1 Cricetulus griseus (Chinese hamster) -
CHO-03 Cricetulus griseus (Chinese hamster) -
CHO CGE Cricetulus griseus (Chinese hamster) -
CHO-CHRM2 Cricetulus griseus (Chinese hamster) -
CHO CRE-SPAP Cricetulus griseus (Chinese hamster) -
CHO 2B7 Cricetulus griseus (Chinese hamster) -
hMORCHO Cricetulus griseus (Chinese hamster) -
CHO Pro-5 Cricetulus griseus (Chinese hamster) -
CHO CCR3/2 Cricetulus griseus (Chinese hamster) -
PPLS-HA-GPR88 CHO Cricetulus griseus (Chinese hamster) -
hTRPV4/CHO Cricetulus griseus (Chinese hamster) -
CHO 1827 Cricetulus griseus (Chinese hamster) -
CHO ducX#98 Cricetulus griseus (Chinese hamster) -
CHO 1829 Cricetulus griseus (Chinese hamster) -
CHO-mtAEQ Cricetulus griseus (Chinese hamster) -
DHB-11 CHO Cricetulus griseus (Chinese hamster) -
CellSensor CRE-bla CHO-K1 Cricetulus griseus (Chinese hamster) -
PathHunter CHO-K1 GLP1R beta-arrestin-2 Cricetulus griseus (Chinese hamster) -
Sf21 Spodoptera frugiperda (Fall armyworm) -
Sf9 Spodoptera frugiperda (Fall armyworm) -
SF-12 Spodoptera frugiperda (Fall armyworm) -
Tni PRO Trichoplusia ni (Cabbage looper) -