General Information of the Cell Line
Cell Line ID
CL000308
Cell Line Name
T-REx-CHO
Synonyms
T-REX-CHO
T-REx CHO
T-REx-CHO-K1
CHO-T-Rex
Category
Spontaneously immortalized cell line
Organism
Cricetulus griseus (Chinese hamster)
Cellosaurus ID
CVCL_D586
Tissue Information
Ovary
Disease None
Map of Molecular Bioactivity Related to the Cell Line
Map of Molecular Bioactivity Related to the Cell Line

Cell Line
Protein
Compound

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Cell Line
Protein ID: PT02149, Ankyrin-like with transmembrane domains protein 1
Compound ID Compound Name Compound Formula
CP0211420
1-[[3-[2-(4-chlorophenyl)ethyl]-1,2,4-oxadiazol-5-yl]methyl]-7-methylpurin-6-one
   Show/Hide
C17H15ClN6O2
 3
1
EC50 > 40000 nM
   TI
   LI
   LO
   TS
2
IC50 = 20 nM
   TI
   LI
   LO
   TS
3
IC50 = 131 nM
   TI
   LI
   LO
   TS
CP0391125
3-[[5-[(E)-2-(4-chlorophenyl)prop-1-enyl]-1,2,4-oxadiazol-3-yl]methyl]pyrido[2,3-d]pyrimidin-4-one
   Show/Hide
C19H14ClN5O2
 3
1
EC50 > 40000 nM
   TI
   LI
   LO
   TS
2
IC50 = 85 nM
   TI
   LI
   LO
   TS
3
IC50 = 116 nM
   TI
   LI
   LO
   TS
CP0391126
1-[[3-[(E)-2-(4-chlorophenyl)prop-1-enyl]-1,2,4-oxadiazol-5-yl]methyl]-7-methylpurin-6-one
   Show/Hide
C18H15ClN6O2
 3
1
EC50 > 40000 nM
   TI
   LI
   LO
   TS
2
IC50 = 63 nM
   TI
   LI
   LO
   TS
3
IC50 = 71 nM
   TI
   LI
   LO
   TS
CP0392459
3-[[3-[2-(4-chlorophenyl)ethyl]-1,2,4-oxadiazol-5-yl]methyl]pyrido[2,3-d]pyrimidin-4-one
   Show/Hide
C18H14ClN5O2
 3
1
EC50 > 40000 nM
   TI
   LI
   LO
   TS
2
IC50 = 41 nM
   TI
   LI
   LO
   TS
3
IC50 = 376 nM
   TI
   LI
   LO
   TS
CP0392463
3-[[3-[2-(4-chlorophenyl)-2-hydroxyethyl]-1,2,4-oxadiazol-5-yl]methyl]pyrido[2,3-d]pyrimidin-4-one
   Show/Hide
C18H14ClN5O3
 3
1
EC50 > 40000 nM
   TI
   LI
   LO
   TS
2
IC50 = 58 nM
   TI
   LI
   LO
   TS
3
IC50 = 251 nM
   TI
   LI
   LO
   TS
CP0425054
3-[[5-[2-(4-chlorophenyl)ethyl]-1,2,4-oxadiazol-3-yl]methyl]pyrido[2,3-d]pyrimidin-4-one
   Show/Hide
C18H14ClN5O2
 3
1
EC50 > 40000 nM
   TI
   LI
   LO
   TS
2
IC50 = 156 nM
   TI
   LI
   LO
   TS
3
IC50 = 1580 nM
   TI
   LI
   LO
   TS
CP0385690
N-[2-[4-(difluoromethoxy)phenyl]ethyl]-2-(8-methyl-4-oxoquinazolin-3-yl)acetamide
   Show/Hide
C20H19F2N3O3
 4
1
EC50 > 47000 nM
   TI
   LI
   LO
   TS
2
IC50 = 685 nM
   TI
   LI
   LO
   TS
3
IC50 = 6270 nM
   TI
   LI
   LO
   TS
4
IC50 > 25000 nM
   TI
   LI
   LO
   TS
CP0395902
6-methyl-5-[2-(trifluoromethyl)phenyl]-1H-indazole
   Show/Hide
C15H11F3N2
 3
1
IC50 = 15 nM
   TI
   LI
   LO
   TS
2
IC50 = 18 nM
   TI
   LI
   LO
   TS
3
IC50 = 20 nM
   TI
   LI
   LO
   TS
CP0404298
3-[[3-[2-(4-chlorophenyl)ethyl]-1,2,4-oxadiazol-5-yl]methyl]-5-methylpyrido[2,3-d]pyrimidin-4-one
   Show/Hide
C19H16ClN5O2
 1
1
IC50 = 16 nM
   TI
   LI
   LO
   TS
CP0440771
6-chloro-5-[2-(trifluoromethyl)phenyl]-1H-indazole
   Show/Hide
C14H8ClF3N2
 1
1
IC50 = 24 nM
   TI
   LI
   LO
   TS
CP0447248
6-(cyclopropylmethoxy)-5-[2-(trifluoromethyl)phenyl]-1H-indazole
   Show/Hide
C18H15F3N2O
 1
1
IC50 = 26 nM
   TI
   LI
   LO
   TS
CP0447265
6-methoxy-5-[2-(trifluoromethyl)phenyl]-1H-indazole
   Show/Hide
C15H11F3N2O
 1
1
IC50 = 26 nM
   TI
   LI
   LO
   TS
CP0395903
6-(trifluoromethoxy)-5-[2-(trifluoromethyl)phenyl]-1H-indazole
   Show/Hide
C15H8F6N2O
 1
1
IC50 = 36 nM
   TI
   LI
   LO
   TS
CP0469033
6-ethoxy-5-[2-(trifluoromethyl)phenyl]-1H-indazole
   Show/Hide
C16H13F3N2O
 1
1
IC50 = 39 nM
   TI
   LI
   LO
   TS
CP0509261
3-[[3-[2-(4-chlorophenyl)-2-fluoroethyl]-1,2,4-oxadiazol-5-yl]methyl]pyrido[2,3-d]pyrimidin-4-one
   Show/Hide
C18H13ClFN5O2
 1
1
IC50 = 41 nM
   TI
   LI
   LO
   TS
CP0443164
6-fluoro-5-[2-(trifluoromethyl)phenyl]-1H-indazole
   Show/Hide
C14H8F4N2
 1
1
IC50 = 48 nM
   TI
   LI
   LO
   TS
CP0440764
6-ethyl-5-[2-(trifluoromethyl)phenyl]-1H-indazole
   Show/Hide
C16H13F3N2
 1
1
IC50 = 50 nM
   TI
   LI
   LO
   TS
CP0506678
6-(difluoromethoxy)-5-[2-(trifluoromethyl)phenyl]-1H-indazole
   Show/Hide
C15H9F5N2O
 1
1
IC50 = 50 nM
   TI
   LI
   LO
   TS
CP0392455
6-[[3-[2-(4-chlorophenyl)ethyl]-1,2,4-oxadiazol-5-yl]methyl]-1-methylpyrazolo[4,3-d]pyrimidin-7-one
   Show/Hide
C17H15ClN6O2
 1
1
IC50 = 52 nM
   TI
   LI
   LO
   TS
CP0506676
6-cyclopropyl-5-[2-(trifluoromethyl)phenyl]-1H-indazole
   Show/Hide
C17H13F3N2
 1
1
IC50 = 61 nM
   TI
   LI
   LO
   TS
CP0425043
N-[2-(4-chlorophenyl)ethyl]-2-(5-methyl-4-oxoquinazolin-3-yl)acetamide
   Show/Hide
C19H18ClN3O2
 1
1
IC50 = 70 nM
   TI
   LI
   LO
   TS
CP0440768
5-[2-(trifluoromethyl)phenyl]-1H-indazole
   Show/Hide
C14H9F3N2
 3
1
IC50 = 84 nM
   TI
   LI
   LO
   TS
2
IC50 = 164 nM
   TI
   LI
   LO
   TS
3
IC50 = 550 nM
   TI
   LI
   LO
   TS
CP0443165
6-(difluoromethyl)-5-[2-(trifluoromethyl)phenyl]-1H-indazole
   Show/Hide
C15H9F5N2
 1
1
IC50 = 103 nM
   TI
   LI
   LO
   TS
CP0461076
5-[2-(trifluoromethyl)phenyl]-1H-indazole-6-carbonitrile
   Show/Hide
C15H8F3N3
 1
1
IC50 = 129 nM
   TI
   LI
   LO
   TS
CP0401633
6-[[3-[2-(4-chlorophenyl)ethyl]-1,2,4-oxadiazol-5-yl]methyl]pyrimido[4,5-c]pyridazin-5-one
   Show/Hide
C17H13ClN6O2
 1
1
IC50 = 136 nM
   TI
   LI
   LO
   TS
CP0447206
6-(methoxymethyl)-5-[2-(trifluoromethyl)phenyl]-1H-indazole
   Show/Hide
C16H13F3N2O
 1
1
IC50 = 142 nM
   TI
   LI
   LO
   TS
CP0469481
3-[[5-[2-(4-chlorophenyl)propyl]-1,2,4-oxadiazol-3-yl]methyl]pyrido[2,3-d]pyrimidin-4-one
   Show/Hide
C19H16ClN5O2
 1
1
IC50 = 150 nM
   TI
   LI
   LO
   TS
CP0469584
3-[[3-[2-(4-chlorophenyl)ethyl]-1,2,4-oxadiazol-5-yl]methyl]pyrimido[4,5-d]pyrimidin-4-one
   Show/Hide
C17H13ClN6O2
 1
1
IC50 = 153 nM
   TI
   LI
   LO
   TS
CP0401643
1-[[5-[(E)-2-(4-chlorophenyl)prop-1-enyl]-1,2,4-oxadiazol-3-yl]methyl]-7-methylpurin-6-one
   Show/Hide
C18H15ClN6O2
 1
1
IC50 = 165 nM
   TI
   LI
   LO
   TS
CP0462431
N-[2-(4-chlorophenyl)ethyl]-2-(8-cyano-4-oxoquinazolin-3-yl)acetamide
   Show/Hide
C19H15ClN4O2
 1
1
IC50 = 201 nM
   TI
   LI
   LO
   TS
CP0472931
1-[[5-[2-(4-chlorophenyl)ethyl]-1,2,4-oxadiazol-3-yl]methyl]-7-methylpurin-6-one
   Show/Hide
C17H15ClN6O2
 1
1
IC50 = 211 nM
   TI
   LI
   LO
   TS
CP0401632
N-[2-(4-chlorophenyl)ethyl]-2-(6-methyl-4-oxoquinazolin-3-yl)acetamide
   Show/Hide
C19H18ClN3O2
 1
1
IC50 = 265 nM
   TI
   LI
   LO
   TS
CP0392454
N-[2-(4-chlorophenyl)ethyl]-2-[4-oxo-8-(trifluoromethyl)quinazolin-3-yl]acetamide
   Show/Hide
C19H15ClF3N3O2
 1
1
IC50 = 286 nM
   TI
   LI
   LO
   TS
CP0443163
4-fluoro-5-[2-(trifluoromethyl)phenyl]-1H-indazole
   Show/Hide
C14H8F4N2
 1
1
IC50 = 296 nM
   TI
   LI
   LO
   TS
CP0547770
5-[5-fluoro-2-(trifluoromethyl)phenyl]-1H-indazole
   Show/Hide
C14H8F4N2
 1
1
IC50 = 306 nM
   TI
   LI
   LO
   TS
CP0548560
5-(2-propan-2-ylphenyl)-1H-indazole
   Show/Hide
C16H16N2
 1
1
IC50 = 514 nM
   TI
   LI
   LO
   TS
CP0489312
5-(2-ethylphenyl)-1H-indazole
   Show/Hide
C15H14N2
 1
1
IC50 = 584 nM
   TI
   LI
   LO
   TS
CP0487896
N-[2-(4-chlorophenyl)ethyl]-2-(8-methyl-4-oxoquinazolin-3-yl)acetamide
   Show/Hide
C19H18ClN3O2
 1
1
IC50 = 802 nM
   TI
   LI
   LO
   TS
CP0425044
3-[[3-[2-(4-chlorophenyl)ethyl]-1,2,4-oxadiazol-5-yl]methyl]pteridin-4-one
   Show/Hide
C17H13ClN6O2
 1
1
IC50 = 918 nM
   TI
   LI
   LO
   TS
CP0472932
3-[[5-[(E)-2-(4-chlorophenyl)ethenyl]-1,2,4-oxadiazol-3-yl]methyl]pyrido[2,3-d]pyrimidin-4-one
   Show/Hide
C18H12ClN5O2
 1
1
IC50 = 933 nM
   TI
   LI
   LO
   TS
CP0547769
6-propan-2-yloxy-5-[2-(trifluoromethyl)phenyl]-1H-indazole
   Show/Hide
C17H15F3N2O
 1
1
IC50 = 970 nM
   TI
   LI
   LO
   TS
CP0462428
N-[2-(4-chlorophenyl)ethyl]-2-(4-oxopyrido[2,3-d]pyrimidin-3-yl)acetamide
   Show/Hide
C17H15ClN4O2
 1
1
IC50 = 1180 nM
   TI
   LI
   LO
   TS
CP0440766
5-(2-chlorophenyl)-1H-indazole
   Show/Hide
C13H9ClN2
 1
1
IC50 = 1230 nM
   TI
   LI
   LO
   TS
CP0556785
5-[2-fluoro-6-(trifluoromethyl)phenyl]-1H-indazole
   Show/Hide
C14H8F4N2
 1
1
IC50 = 1230 nM
   TI
   LI
   LO
   TS
CP0469034
2-(1H-indazol-5-yl)benzonitrile
   Show/Hide
C14H9N3
 1
1
IC50 = 1290 nM
   TI
   LI
   LO
   TS
CP0498112
N-[2-(4-chlorophenyl)ethyl]-2-(8-fluoro-4-oxoquinazolin-3-yl)acetamide
   Show/Hide
C18H15ClFN3O2
 1
1
IC50 = 1330 nM
   TI
   LI
   LO
   TS
CP0499832
N-[2-(4-chlorophenyl)ethyl]-2-(8-methoxy-4-oxoquinazolin-3-yl)acetamide
   Show/Hide
C19H18ClN3O3
 1
1
IC50 = 1460 nM
   TI
   LI
   LO
   TS
CP0404296
N-[2-(4-chlorophenyl)ethyl]-2-(4-oxopyrido[3,4-d]pyrimidin-3-yl)acetamide
   Show/Hide
C17H15ClN4O2
 1
1
IC50 = 1710 nM
   TI
   LI
   LO
   TS
CP0467962
3-[[3-[2-(6-chloropyridin-3-yl)ethyl]-1,2,4-oxadiazol-5-yl]methyl]pyrido[2,3-d]pyrimidin-4-one
   Show/Hide
C17H13ClN6O2
 1
1
IC50 = 2120 nM
   TI
   LI
   LO
   TS
CP0404297
3-[[5-[2-(4-chlorophenyl)ethyl]-1,3,4-oxadiazol-2-yl]methyl]pyrido[2,3-d]pyrimidin-4-one
   Show/Hide
C18H14ClN5O2
 1
1
IC50 = 2180 nM
   TI
   LI
   LO
   TS
CP0499258
5-[2-(difluoromethyl)phenyl]-1H-indazole
   Show/Hide
C14H10F2N2
 1
1
IC50 = 2200 nM
   TI
   LI
   LO
   TS
CP0440762
3-methyl-5-[2-(trifluoromethyl)phenyl]-2H-indazole
   Show/Hide
C15H11F3N2
 1
1
IC50 = 3090 nM
   TI
   LI
   LO
   TS
CP0443162
5-(2-tert-butylphenyl)-1H-indazole
   Show/Hide
C17H18N2
 1
1
IC50 = 3400 nM
   TI
   LI
   LO
   TS
CP0481195
5-[2-(trifluoromethoxy)phenyl]-1H-indazole
   Show/Hide
C14H9F3N2O
 1
1
IC50 = 3430 nM
   TI
   LI
   LO
   TS
CP0440767
5-(2-fluorophenyl)-1H-indazole
   Show/Hide
C13H9FN2
 1
1
IC50 = 3950 nM
   TI
   LI
   LO
   TS
CP0461078
7-methyl-5-[2-(trifluoromethyl)phenyl]-1H-indazole
   Show/Hide
C15H11F3N2
 1
1
IC50 = 6720 nM
   TI
   LI
   LO
   TS
CP0440763
1-methyl-5-[2-(trifluoromethyl)phenyl]indazole
   Show/Hide
C15H11F3N2
 1
1
IC50 = 7410 nM
   TI
   LI
   LO
   TS
CP0440760
5-(2-methylphenyl)-1H-indazole
   Show/Hide
C14H12N2
 1
1
IC50 = 7810 nM
   TI
   LI
   LO
   TS
CP0440769
5-[3-fluoro-2-(trifluoromethyl)phenyl]-1H-indazole
   Show/Hide
C14H8F4N2
 1
1
IC50 = 8900 nM
   TI
   LI
   LO
   TS
CP0401638
N-[2-(3-methoxyphenyl)ethyl]-2-(8-methyl-4-oxoquinazolin-3-yl)acetamide
   Show/Hide
C20H21N3O3
 1
1
IC50 > 16700 nM
   TI
   LI
   LO
   TS
CP0401640
N-[2-(2-methoxyphenyl)ethyl]-2-(8-methyl-4-oxoquinazolin-3-yl)acetamide
   Show/Hide
C20H21N3O3
 1
1
IC50 > 16700 nM
   TI
   LI
   LO
   TS
CP0404295
N-[2-(4-chlorophenyl)ethyl]-2-(4-oxoquinazolin-3-yl)acetamide
   Show/Hide
C18H16ClN3O2
 1
1
IC50 > 16700 nM
   TI
   LI
   LO
   TS
CP0481740
6-propan-2-yl-5-[2-(trifluoromethyl)phenyl]-1H-indazole
   Show/Hide
C17H15F3N2
 1
1
IC50 = 25400 nM
   TI
   LI
   LO
   TS
CP0440759
5-phenyl-1H-indazole
   Show/Hide
C13H10N2
 1
1
IC50 > 30000 nM
   TI
   LI
   LO
   TS
CP0440761
5-[4-fluoro-2-(trifluoromethyl)phenyl]-1H-indazole
   Show/Hide
C14H8F4N2
 1
1
IC50 = 30000 nM
   TI
   LI
   LO
   TS
CP0440765
N-methyl-5-[2-(trifluoromethyl)phenyl]-1H-indazole-6-carboxamide
   Show/Hide
C16H12F3N3O
 1
1
IC50 > 30000 nM
   TI
   LI
   LO
   TS
CP0401641
N-[2-(4-chlorophenyl)ethyl]-2-(7-methyl-4-oxoquinazolin-3-yl)acetamide
   Show/Hide
C19H18ClN3O2
 1
1
IC50 > 4200 nM
   TI
   LI
   LO
   TS
CP0483177
2-(8-methyl-4-oxoquinazolin-3-yl)-N-(2-phenylethyl)acetamide
   Show/Hide
C19H19N3O2
 1
1
IC50 > 8330 nM
   TI
   LI
   LO
   TS
Protein family and CMB statistics Related to the Cell Line
Cell Lines Derived from the same Tissue Source (Ovary)
Cell Line Name Organism Disease
SW626 Homo sapiens (Human) Colon adenocarcinoma
FU-OV-1 Homo sapiens (Human) High grade ovarian serous adenocarcinoma
TOV-21G Homo sapiens (Human) Ovarian clear cell adenocarcinoma
ES-2 Homo sapiens (Human) Ovarian clear cell adenocarcinoma
A2780 Homo sapiens (Human) Ovarian endometrioid adenocarcinoma
A2780ADR Homo sapiens (Human) Ovarian endometrioid adenocarcinoma
IGROV-1 Homo sapiens (Human) Ovarian endometrioid adenocarcinoma
CHO Cricetulus griseus (Chinese hamster) -
CHO-K1 Cricetulus griseus (Chinese hamster) -
CHO/Galpha16 Cricetulus griseus (Chinese hamster) -
CHOP Cricetulus griseus (Chinese hamster) -
CHO Pro-4 MtxRII OuaR-2-4 Cricetulus griseus (Chinese hamster) -
Flp-In-CHO Cricetulus griseus (Chinese hamster) -
CHO-DXB11 Cricetulus griseus (Chinese hamster) -
CHO-CPR C10 Cricetulus griseus (Chinese hamster) -
PathHunter CHO-K1 EDG1 beta-arrestin Cricetulus griseus (Chinese hamster) -
CHO-S Cricetulus griseus (Chinese hamster) -
CHO-7 Cricetulus griseus (Chinese hamster) -
CHO-T Cricetulus griseus (Chinese hamster) -
ValiScreen human CRTH2 Cricetulus griseus (Chinese hamster) -
PathHunter CHO-K1 GLP1R beta-arrestin-1 Cricetulus griseus (Chinese hamster) -
CHO-K1/CRE-Luc Cricetulus griseus (Chinese hamster) -
CHO-hTRPV1 Cricetulus griseus (Chinese hamster) -
Lec1 Cricetulus griseus (Chinese hamster) -
CHO-N9 Cricetulus griseus (Chinese hamster) -
CHO/IR Cricetulus griseus (Chinese hamster) -
CHO-K1/Gqi5 Cricetulus griseus (Chinese hamster) -
CHO-K9 Cricetulus griseus (Chinese hamster) -
CHO-A12 Cricetulus griseus (Chinese hamster) -
CHO E1a Cricetulus griseus (Chinese hamster) -
PathHunter CHO-K1 CXCR7 beta-arrestin Cricetulus griseus (Chinese hamster) -
R2/PCFT4 Cricetulus griseus (Chinese hamster) -
Chinese hamster RT16 Cricetulus griseus (Chinese hamster) -
CHO-A1 Cricetulus griseus (Chinese hamster) -
CHO-D-/aequorin Cricetulus griseus (Chinese hamster) -
CHO-DUKX-A2 Cricetulus griseus (Chinese hamster) -
Lec3.2.8.1 Cricetulus griseus (Chinese hamster) -
CellSensor NFAT-bla CHO-K1 Cricetulus griseus (Chinese hamster) -
Chinese hamster PC43-10 Cricetulus griseus (Chinese hamster) -
CHO-A3 Cricetulus griseus (Chinese hamster) -
CHO/VR1 Cricetulus griseus (Chinese hamster) -
CHO-hgamma Cricetulus griseus (Chinese hamster) -
CHO-1 Cricetulus griseus (Chinese hamster) -
CHO-03 Cricetulus griseus (Chinese hamster) -
CHO CGE Cricetulus griseus (Chinese hamster) -
CHO-CHRM2 Cricetulus griseus (Chinese hamster) -
CHO CRE-SPAP Cricetulus griseus (Chinese hamster) -
CHO 2B7 Cricetulus griseus (Chinese hamster) -
hMORCHO Cricetulus griseus (Chinese hamster) -
CHO Pro-5 Cricetulus griseus (Chinese hamster) -
CHO CCR3/2 Cricetulus griseus (Chinese hamster) -
PPLS-HA-GPR88 CHO Cricetulus griseus (Chinese hamster) -
hTRPV4/CHO Cricetulus griseus (Chinese hamster) -
CHO 1827 Cricetulus griseus (Chinese hamster) -
CHO ducX#98 Cricetulus griseus (Chinese hamster) -
CHO 1829 Cricetulus griseus (Chinese hamster) -
CHO-mtAEQ Cricetulus griseus (Chinese hamster) -
DHB-11 CHO Cricetulus griseus (Chinese hamster) -
CellSensor CRE-bla CHO-K1 Cricetulus griseus (Chinese hamster) -
PathHunter CHO-K1 GLP1R beta-arrestin-2 Cricetulus griseus (Chinese hamster) -
Sf21 Spodoptera frugiperda (Fall armyworm) -
Sf9 Spodoptera frugiperda (Fall armyworm) -
SF-12 Spodoptera frugiperda (Fall armyworm) -
Tni PRO Trichoplusia ni (Cabbage looper) -