Brief Information of the Cell Line and Protein
Cell Line ID: CL000308 , T-REx-CHO
 Cell Line Info 
Synonyms
T-REX-CHO
T-REx CHO
T-REx-CHO-K1
CHO-T-Rex
Category Spontaneously immortalized cell line
Organism
Cricetulus griseus (Chinese hamster)
Cellosaurus ID
CVCL_D586
Protein ID: PT06269 , G-protein coupled receptor 6
 Protein Info 
Gene Name GPR6
Organism Homo sapiens, Human
Protein Classification Membrane receptor
Uniprot ID P46095
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000308
 Cell Line Info 
 Protein ID: PT06269
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0353832
 Compound Info 
N-cyclopropyl-3-[4-[(2,4-difluorophenyl)methyl]piperazin-1-yl]pyrido[3,4-b]pyrazin-2-amine
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C21H22F2N6
  1
1
Ki = 7 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0231638
 Compound Info 
1-[2-[4-(2,4-difluorophenoxy)piperidin-1-yl]-3-[[(3R)-oxolan-3-yl]amino]-7,8-dihydro-5H-pyrido[3,4-b]pyrazin-6-yl]ethanone
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C24H29F2N5O3
  1
1
Ki = 9.4 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0542590
 Compound Info 
1-[2-[4-(2,4-difluorophenoxy)piperidin-1-yl]-3-(propan-2-ylamino)-5H-pyrido[3,4-b]pyrazin-6-yl]ethanone
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C23H27F2N5O2
  1
1
Ki = 16 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS