General Information of the Cell Line
Cell Line ID
CL000943
Cell Line Name
CellSensor NFAT-bla CHO-K1
Synonyms
NFAT-bla CHO-K1
Category
Spontaneously immortalized cell line
Organism
Cricetulus griseus (Chinese hamster)
Tissue Information
Ovary
Disease None
Map of Molecular Bioactivity Related to the Cell Line
Map of Molecular Bioactivity Related to the Cell Line

Cell Line
Protein
Compound

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Cell Line
Protein ID: PT01996, Bombesin receptor subtype-3
Compound ID Compound Name Compound Formula
CP0410792
1-[6-[4-(trifluoromethoxy)phenyl]sulfonyl-2-(trifluoromethyl)-5,11-dihydropyrido[3,2-c][1,5]benzodiazepin-7-yl]cyclobutane-1-carboxamide
   Show/Hide
C25H20F6N4O4S
 1
1
IC50 = 0.5 nM
   TI
   LI
   LO
   TS
CP0504219
2-methyl-2-[6-[4-(trifluoromethoxy)phenyl]sulfonyl-2-(trifluoromethyl)-5,11-dihydropyrido[3,2-c][1,5]benzodiazepin-7-yl]propanamide
   Show/Hide
C24H20F6N4O4S
 1
1
IC50 = 0.5 nM
   TI
   LI
   LO
   TS
CP0385700
2-[3-[1-[6-[4-(trifluoromethoxy)phenyl]sulfonyl-2-(trifluoromethyl)-5,11-dihydropyrido[3,2-c][1,5]benzodiazepin-7-yl]cyclobutyl]-1,2,4-oxadiazol-5-yl]propan-2-ol
   Show/Hide
C29H25F6N5O5S
 1
1
IC50 = 0.6 nM
   TI
   LI
   LO
   TS
CP0315938
[3-[6-(4-tert-butylphenyl)sulfonyl-2-(trifluoromethyl)-5,11-dihydropyrido[3,2-c][1,5]benzodiazepin-7-yl]-1,2,4-oxadiazol-5-yl]methanol
   Show/Hide
C26H24F3N5O4S
 1
1
IC50 = 0.7 nM
   TI
   LI
   LO
   TS
CP0315941
6-(4-tert-butylphenyl)sulfonyl-7-(1-methylpyrazol-4-yl)-2-(trifluoromethyl)-5,11-dihydropyrido[3,2-c][1,5]benzodiazepine
   Show/Hide
C27H26F3N5O2S
 1
1
IC50 = 0.76 nM
   TI
   LI
   LO
   TS
CP0179883
2-[3-[6-(4-tert-butylphenyl)sulfonyl-2-(trifluoromethyl)-5,11-dihydropyrido[3,2-c][1,5]benzodiazepin-7-yl]-1,2,4-oxadiazol-5-yl]propan-2-ol
   Show/Hide
C28H28F3N5O4S
 1
1
IC50 = 0.9 nM
   TI
   LI
   LO
   TS
CP0191374
3-[6-(4-tert-butylphenyl)sulfonyl-2-(trifluoromethyl)-5,11-dihydropyrido[3,2-c][1,5]benzodiazepin-7-yl]-1,2,4-oxadiazole
   Show/Hide
C25H22F3N5O3S
 1
1
IC50 = 1.1 nM
   TI
   LI
   LO
   TS
CP0110516
(1S)-1-[3-[6-(4-tert-butylphenyl)sulfonyl-2-(trifluoromethyl)-5,11-dihydropyrido[3,2-c][1,5]benzodiazepin-7-yl]-1,2,4-oxadiazol-5-yl]ethanol
   Show/Hide
C27H26F3N5O4S
 1
1
IC50 = 1.2 nM
   TI
   LI
   LO
   TS
CP0385699
2-[3-[2-[6-[4-(trifluoromethoxy)phenyl]sulfonyl-2-(trifluoromethyl)-5,11-dihydropyrido[3,2-c][1,5]benzodiazepin-7-yl]propan-2-yl]-1,2,4-oxadiazol-5-yl]propan-2-ol
   Show/Hide
C28H25F6N5O5S
 1
1
IC50 = 1.4 nM
   TI
   LI
   LO
   TS
CP0315773
6-(4-tert-butylphenyl)sulfonyl-7-piperidin-4-yl-2-(trifluoromethyl)-5,11-dihydropyrido[3,2-c][1,5]benzodiazepine
   Show/Hide
C28H31F3N4O2S
 1
1
IC50 = 1.4 nM
   TI
   LI
   LO
   TS
CP0085078
2-[3-[6-(4-propan-2-ylphenyl)sulfonyl-2-(trifluoromethyl)-5,11-dihydropyrido[3,2-c][1,5]benzodiazepin-7-yl]-1,2,4-oxadiazol-5-yl]propan-2-ol
   Show/Hide
C27H26F3N5O4S
 1
1
IC50 = 1.7 nM
   TI
   LI
   LO
   TS
CP0315939
6-(4-tert-butylphenyl)sulfonyl-7-pyridin-3-yl-2-(trifluoromethyl)-5,11-dihydropyrido[3,2-c][1,5]benzodiazepine
   Show/Hide
C28H25F3N4O2S
 1
1
IC50 = 1.72 nM
   TI
   LI
   LO
   TS
CP0315940
(1R)-1-[3-[6-(4-tert-butylphenyl)sulfonyl-2-(trifluoromethyl)-5,11-dihydropyrido[3,2-c][1,5]benzodiazepin-7-yl]-1,2,4-oxadiazol-5-yl]ethanol
   Show/Hide
C27H26F3N5O4S
 1
1
IC50 = 1.9 nM
   TI
   LI
   LO
   TS
CP0436009
N-methyl-1-[6-[4-(trifluoromethoxy)phenyl]sulfonyl-2-(trifluoromethyl)-5,11-dihydropyrido[3,2-c][1,5]benzodiazepin-7-yl]cyclobutane-1-carboxamide
   Show/Hide
C26H22F6N4O4S
 1
1
IC50 = 2.1 nM
   TI
   LI
   LO
   TS
CP0256765
2-[3-[6-[4-(trifluoromethoxy)phenyl]sulfonyl-2-(trifluoromethyl)-5,11-dihydropyrido[3,2-c][1,5]benzodiazepin-7-yl]-1,2,4-oxadiazol-5-yl]propan-2-ol
   Show/Hide
C25H19F6N5O5S
 1
1
IC50 = 3.6 nM
   TI
   LI
   LO
   TS
CP0462865
2-(4-(2-(4-(2,2-dimethylbutyl)-1H-imidazol-2-yl)ethyl)phenyl)-6-methylpyridine
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C23H29N3
 1
1
IC50 = 6.3 nM
   TI
   LI
   LO
   TS
CP0430445
6-(4-(2-(4-(2,2-dimethylbutyl)-1H-imidazol-2-yl)ethyl)phenyl)pyridin-2-amine
   Show/Hide
C22H28N4
 1
1
IC50 = 7.3 nM
   TI
   LI
   LO
   TS
CP0377000
3-(4-(2-(4-(2,2-dimethylbutyl)-1H-imidazol-2-yl)ethyl)phenyl)pyridine
   Show/Hide
C22H27N3
 1
1
IC50 = 7.5 nM
   TI
   LI
   LO
   TS
CP0194393
2-[3-[2-(trifluoromethyl)-6-[4-(trifluoromethyl)phenyl]sulfonyl-5,11-dihydropyrido[3,2-c][1,5]benzodiazepin-7-yl]-1,2,4-oxadiazol-5-yl]propan-2-ol
   Show/Hide
C25H19F6N5O4S
 1
1
IC50 = 8.3 nM
   TI
   LI
   LO
   TS
CP0402311
4-(4-(2-(4-(2,2-dimethylbutyl)-1H-imidazol-2-yl)ethyl)phenyl)isothiazole
   Show/Hide
C20H25N3S
 1
1
IC50 = 10 nM
   TI
   LI
   LO
   TS
CP0365995
4'-(2-(4-(2,2-dimethylbutyl)-1H-imidazol-2-yl)ethyl)biphenyl-2-carboxylic acid
   Show/Hide
C24H28N2O2
 1
1
IC50 = 11 nM
   TI
   LI
   LO
   TS
CP0390896
5-(4-(2-(4-(2,2-dimethylbutyl)-1H-imidazol-2-yl)ethyl)phenyl)isothiazole
   Show/Hide
C20H25N3S
 1
1
IC50 = 11 nM
   TI
   LI
   LO
   TS
CP0225161
2-(4-(2-(4-(2,2-dimethylbutyl)-1H-imidazol-2-yl)ethyl)phenyl)pyridine
   Show/Hide
C22H27N3
 1
1
IC50 = 18 nM
   TI
   LI
   LO
   TS
CP0260398
2-[3-[6-[4-(difluoromethoxy)phenyl]sulfonyl-2-(trifluoromethyl)-5,11-dihydropyrido[3,2-c][1,5]benzodiazepin-7-yl]-1,2,4-oxadiazol-5-yl]propan-2-ol
   Show/Hide
C25H20F5N5O5S
 1
1
IC50 = 18 nM
   TI
   LI
   LO
   TS
CP0401480
2-(4-(2-(4-(2,2-dimethylbutyl)-1H-imidazol-2-yl)ethyl)phenyl)-5-fluoropyridine
   Show/Hide
C22H26FN3
 1
1
IC50 = 19 nM
   TI
   LI
   LO
   TS
CP0410795
1-(4-(2-(4-(2,2-dimethylbutyl)-1H-imidazol-2-yl)ethyl)phenyl)piperidine
   Show/Hide
C22H33N3
 1
1
IC50 = 28 nM
   TI
   LI
   LO
   TS
CP0192143
3-[6-(4-tert-butylphenyl)sulfonyl-2-(trifluoromethyl)-5,11-dihydropyrido[3,2-c][1,5]benzodiazepin-7-yl]-4H-1,2,4-oxadiazol-5-one
   Show/Hide
C25H22F3N5O4S
 1
1
IC50 = 29 nM
   TI
   LI
   LO
   TS
CP0402312
1-(4-(2-(4-(2,2-dimethylbutyl)-1H-imidazol-2-yl)ethyl)phenyl)-1H-pyrazole
   Show/Hide
C20H26N4
 1
1
IC50 = 33 nM
   TI
   LI
   LO
   TS
CP0462864
4'-(2-(4-(cyclohexylmethyl)-1H-imidazol-2-yl)ethyl)-4,5-difluorobiphenyl-2-carboxylic acid
   Show/Hide
C25H26F2N2O2
 1
1
IC50 = 36 nM
   TI
   LI
   LO
   TS
CP0507291
4-(4-(2-(4-(2,2-dimethylbutyl)-1H-imidazol-2-yl)ethyl)phenyl)-1,2,3-thiadiazole
   Show/Hide
C19H24N4S
 1
1
IC50 = 45 nM
   TI
   LI
   LO
   TS
CP0390895
6-(4-(2-(4-(2,2-dimethylbutyl)-1H-imidazol-2-yl)ethyl)phenyl)pyridin-2-ol
   Show/Hide
C22H27N3O
 1
1
IC50 = 51 nM
   TI
   LI
   LO
   TS
CP0401483
2-(4-(2-(4-(2,2-dimethylbutyl)-1H-imidazol-2-yl)ethyl)phenyl)pyrazine
   Show/Hide
C21H26N4
 1
1
IC50 = 51 nM
   TI
   LI
   LO
   TS
CP0417715
4-(4-(2-(4-(2,2-dimethylbutyl)-1H-imidazol-2-yl)ethyl)phenyl)pyridine
   Show/Hide
C22H27N3
 1
1
IC50 = 101 nM
   TI
   LI
   LO
   TS
CP0400009
6-(4-(2-(4-(2,2-dimethylbutyl)-1H-imidazol-2-yl)ethyl)phenyl)picolinonitrile
   Show/Hide
C23H26N4
 1
1
IC50 = 140 nM
   TI
   LI
   LO
   TS
CP0417714
2-(4-(2-(4-(cyclopentylmethyl)-1H-imidazol-2-yl)ethyl)phenyl)pyridine
   Show/Hide
C22H25N3
 1
1
IC50 = 177 nM
   TI
   LI
   LO
   TS
CP0401489
2-(4-(2-(4-(2,2-dimethylbutyl)-1H-imidazol-2-yl)ethyl)phenyl)-2H-tetrazole
   Show/Hide
C18H24N6
 1
1
IC50 = 205 nM
   TI
   LI
   LO
   TS
CP0390897
1-(4-(2-(4-(2,2-dimethylbutyl)-1H-imidazol-2-yl)ethyl)phenyl)-1H-1,2,4-triazole
   Show/Hide
C19H25N5
 1
1
IC50 = 340 nM
   TI
   LI
   LO
   TS
CP0401488
1-(4-(2-(4-(2,2-dimethylbutyl)-1H-imidazol-2-yl)ethyl)phenyl)-1H-1,2,3-triazole
   Show/Hide
C19H25N5
 1
1
IC50 = 390 nM
   TI
   LI
   LO
   TS
CP0401495
3-(4-(2-(4-(2,2-dimethylbutyl)-1H-imidazol-2-yl)ethyl)phenyl)picolinic acid
   Show/Hide
C23H27N3O2
 1
1
IC50 = 560 nM
   TI
   LI
   LO
   TS
CP0401496
6-(4-(2-(4-(2,2-dimethylbutyl)-1H-imidazol-2-yl)ethyl)phenyl)picolinic acid
   Show/Hide
C23H27N3O2
 1
1
IC50 = 2821 nM
   TI
   LI
   LO
   TS
CP0373910
4'-(2-(5-butyl-1H-imidazol-2-yl)-5-hydroxypentyl)biphenyl-2-carboxylic acid
   Show/Hide
C25H30N2O3
 1
1
IC50 = 3676 nM
   TI
   LI
   LO
   TS
Protein family and CMB statistics Related to the Cell Line
Cell Lines Derived from the same Tissue Source (Ovary)
Cell Line Name Organism Disease
SW626 Homo sapiens (Human) Colon adenocarcinoma
FU-OV-1 Homo sapiens (Human) High grade ovarian serous adenocarcinoma
TOV-21G Homo sapiens (Human) Ovarian clear cell adenocarcinoma
ES-2 Homo sapiens (Human) Ovarian clear cell adenocarcinoma
A2780 Homo sapiens (Human) Ovarian endometrioid adenocarcinoma
A2780ADR Homo sapiens (Human) Ovarian endometrioid adenocarcinoma
IGROV-1 Homo sapiens (Human) Ovarian endometrioid adenocarcinoma
CHO Cricetulus griseus (Chinese hamster) -
CHO-K1 Cricetulus griseus (Chinese hamster) -
CHO/Galpha16 Cricetulus griseus (Chinese hamster) -
CHOP Cricetulus griseus (Chinese hamster) -
T-REx-CHO Cricetulus griseus (Chinese hamster) -
CHO Pro-4 MtxRII OuaR-2-4 Cricetulus griseus (Chinese hamster) -
Flp-In-CHO Cricetulus griseus (Chinese hamster) -
CHO-DXB11 Cricetulus griseus (Chinese hamster) -
CHO-CPR C10 Cricetulus griseus (Chinese hamster) -
PathHunter CHO-K1 EDG1 beta-arrestin Cricetulus griseus (Chinese hamster) -
CHO-S Cricetulus griseus (Chinese hamster) -
CHO-7 Cricetulus griseus (Chinese hamster) -
CHO-T Cricetulus griseus (Chinese hamster) -
ValiScreen human CRTH2 Cricetulus griseus (Chinese hamster) -
PathHunter CHO-K1 GLP1R beta-arrestin-1 Cricetulus griseus (Chinese hamster) -
CHO-K1/CRE-Luc Cricetulus griseus (Chinese hamster) -
CHO-hTRPV1 Cricetulus griseus (Chinese hamster) -
Lec1 Cricetulus griseus (Chinese hamster) -
CHO-N9 Cricetulus griseus (Chinese hamster) -
CHO/IR Cricetulus griseus (Chinese hamster) -
CHO-K1/Gqi5 Cricetulus griseus (Chinese hamster) -
CHO-K9 Cricetulus griseus (Chinese hamster) -
CHO-A12 Cricetulus griseus (Chinese hamster) -
CHO E1a Cricetulus griseus (Chinese hamster) -
PathHunter CHO-K1 CXCR7 beta-arrestin Cricetulus griseus (Chinese hamster) -
R2/PCFT4 Cricetulus griseus (Chinese hamster) -
Chinese hamster RT16 Cricetulus griseus (Chinese hamster) -
CHO-A1 Cricetulus griseus (Chinese hamster) -
CHO-D-/aequorin Cricetulus griseus (Chinese hamster) -
CHO-DUKX-A2 Cricetulus griseus (Chinese hamster) -
Lec3.2.8.1 Cricetulus griseus (Chinese hamster) -
Chinese hamster PC43-10 Cricetulus griseus (Chinese hamster) -
CHO-A3 Cricetulus griseus (Chinese hamster) -
CHO/VR1 Cricetulus griseus (Chinese hamster) -
CHO-hgamma Cricetulus griseus (Chinese hamster) -
CHO-1 Cricetulus griseus (Chinese hamster) -
CHO-03 Cricetulus griseus (Chinese hamster) -
CHO CGE Cricetulus griseus (Chinese hamster) -
CHO-CHRM2 Cricetulus griseus (Chinese hamster) -
CHO CRE-SPAP Cricetulus griseus (Chinese hamster) -
CHO 2B7 Cricetulus griseus (Chinese hamster) -
hMORCHO Cricetulus griseus (Chinese hamster) -
CHO Pro-5 Cricetulus griseus (Chinese hamster) -
CHO CCR3/2 Cricetulus griseus (Chinese hamster) -
PPLS-HA-GPR88 CHO Cricetulus griseus (Chinese hamster) -
hTRPV4/CHO Cricetulus griseus (Chinese hamster) -
CHO 1827 Cricetulus griseus (Chinese hamster) -
CHO ducX#98 Cricetulus griseus (Chinese hamster) -
CHO 1829 Cricetulus griseus (Chinese hamster) -
CHO-mtAEQ Cricetulus griseus (Chinese hamster) -
DHB-11 CHO Cricetulus griseus (Chinese hamster) -
CellSensor CRE-bla CHO-K1 Cricetulus griseus (Chinese hamster) -
PathHunter CHO-K1 GLP1R beta-arrestin-2 Cricetulus griseus (Chinese hamster) -
Sf21 Spodoptera frugiperda (Fall armyworm) -
Sf9 Spodoptera frugiperda (Fall armyworm) -
SF-12 Spodoptera frugiperda (Fall armyworm) -
Tni PRO Trichoplusia ni (Cabbage looper) -