| Compound ID |
Compound Name |
Compound Formula |
|
CP0906299
|
(trans)-N-Methyl-4-((8-methyl-2-oxo-6-(thiazol-5-yl)-1,2-dihydroquinolin-4-yl)amino)cyclohexanecarboxamide
Show/Hide
|
C21H24N4O2S
|
1
|
| 1 |
IC50 < 0.18 nM
|
|
|
|
CP0548367
|
4-[[4-(2-methoxyethoxy)cyclohexyl]amino]-8-methyl-6-(1,3-thiazol-5-yl)-1H-quinolin-2-one
Show/Hide
|
C22H27N3O3S
|
1
|
| 1 |
IC50 = 0.62 nM
|
|
|
|
CP0488234
|
4-[(4-methoxycyclohexyl)amino]-8-methyl-6-(1,3-thiazol-5-yl)-1H-quinolin-2-one
Show/Hide
|
C20H23N3O2S
|
1
|
| 1 |
IC50 = 0.65 nM
|
|
|
|
CP0450444
|
4-[[1,8-dimethyl-2-oxo-6-(1,3-thiazol-5-yl)quinolin-4-yl]amino]-N-methylcyclohexane-1-carboxamide
Show/Hide
|
C22H26N4O2S
|
1
|
| 1 |
IC50 = 0.78 nM
|
|
|
|
CP0450443
|
N-methyl-4-[[2-oxo-6-(1,3-thiazol-5-yl)-1H-quinolin-4-yl]amino]cyclohexane-1-carboxamide
Show/Hide
|
C20H22N4O2S
|
1
|
| 1 |
IC50 = 0.9 nM
|
|
|
|
CP0482600
|
4-[(4-methoxycyclohexyl)amino]-8-methyl-6-(1,3-thiazol-5-yl)-1H-quinazolin-2-one
Show/Hide
|
C19H22N4O2S
|
1
|
| 1 |
IC50 = 1 nM
|
|
|
|
CP0530442
|
CHEMBL3426066
Show/Hide
|
C21H24N4O2S
|
1
|
| 1 |
IC50 = 1.1 nM
|
|
|
|
CP0859087
|
4-(((trans)-4-(2-Methoxyethoxy)cyclohexyl)amino)-6-(thiazol-5-yl)quinolin-2(1H)-one
Show/Hide
|
C21H25N3O3S
|
1
|
| 1 |
IC50 = 1.3 nM
|
|
|
|
CP0249204
|
4-[(4-methoxycyclohexyl)amino]-1,8-dimethyl-6-(1,3-thiazol-5-yl)quinolin-2-one
Show/Hide
|
C21H25N3O2S
|
1
|
| 1 |
IC50 = 1.4 nM
|
|
|
|
CP0469833
|
4-[(4-methoxycyclohexyl)amino]-1-methyl-6-(1,3-thiazol-5-yl)quinolin-2-one
Show/Hide
|
C20H23N3O2S
|
1
|
| 1 |
IC50 = 1.6 nM
|
|
|
|
CP0555864
|
4-[[4-(2-methoxyethoxy)cyclohexyl]amino]-1,8-dimethyl-6-(1,3-thiazol-5-yl)quinolin-2-one
Show/Hide
|
C23H29N3O3S
|
1
|
| 1 |
IC50 = 1.6 nM
|
|
|
|
CP0188353
|
4-[[4-(2-methoxyethoxy)cyclohexyl]amino]-1-methyl-6-(1,3-thiazol-5-yl)quinolin-2-one
Show/Hide
|
C22H27N3O3S
|
1
|
| 1 |
IC50 = 1.9 nM
|
|
|
|
CP0528854
|
4-[(4-hydroxycyclohexyl)amino]-1-methyl-6-(1,3-thiazol-5-yl)quinolin-2-one
Show/Hide
|
C19H21N3O2S
|
1
|
| 1 |
IC50 = 2.5 nM
|
|
|
|
CP0389468
|
4-[[8-methoxy-6-(1,3-thiazol-5-yl)quinazolin-4-yl]amino]benzamide
Show/Hide
|
C19H15N5O2S
|
1
|
| 1 |
IC50 = 4 nM
|
|
|
|
CP0400543
|
4-(3-chloro-4-fluoroanilino)-8-methyl-6-(1,3-thiazol-5-yl)-1H-quinazolin-2-one
Show/Hide
|
C18H12ClFN4OS
|
1
|
| 1 |
IC50 = 4 nM
|
|
|
|
CP0566856
|
8-methyl-4-(oxan-4-ylamino)-6-(1,3-thiazol-5-yl)-1H-quinolin-2-one
Show/Hide
|
C18H19N3O2S
|
1
|
| 1 |
IC50 = 4.5 nM
|
|
|
|
CP0414620
|
1-ethyl-4-[[4-(2-methoxyethoxy)cyclohexyl]amino]-6-(1,3-thiazol-5-yl)quinolin-2-one
Show/Hide
|
C23H29N3O3S
|
1
|
| 1 |
IC50 = 5.2 nM
|
|
|
|
CP0400580
|
1,8-dimethyl-4-(oxan-4-ylamino)-6-(1,3-thiazol-5-yl)quinolin-2-one
Show/Hide
|
C19H21N3O2S
|
1
|
| 1 |
IC50 = 6 nM
|
|
|
|
CP0414619
|
4-[[1-ethyl-2-oxo-6-(1,3-thiazol-5-yl)quinolin-4-yl]amino]-N-methylcyclohexane-1-carboxamide
Show/Hide
|
C22H26N4O2S
|
1
|
| 1 |
IC50 = 6.1 nM
|
|
|
|
CP0448226
|
N-(4-methylcyclohexyl)-6-(1,3-thiazol-5-yl)quinazolin-4-amine
Show/Hide
|
C18H20N4S
|
1
|
| 1 |
IC50 = 7 nM
|
|
|
|
CP0489213
|
4-[[2,8-dimethyl-6-(1,3-thiazol-5-yl)quinazolin-4-yl]amino]-N-methylcyclohexane-1-carboxamide
Show/Hide
|
C21H25N5OS
|
1
|
| 1 |
IC50 = 7 nM
|
|
|
|
CP0400544
|
4-[[4-(2-methoxyethoxy)cyclohexyl]amino]-1-methyl-6-(1,3-thiazol-5-yl)quinazolin-2-one
Show/Hide
|
C21H26N4O3S
|
1
|
| 1 |
IC50 = 8 nM
|
|
|
|
CP0489212
|
4-[(4-methoxycyclohexyl)amino]-1-methyl-6-(1,3-thiazol-5-yl)quinazolin-2-one
Show/Hide
|
C19H22N4O2S
|
1
|
| 1 |
IC50 = 8 nM
|
|
|
|
CP0555863
|
4-[[6-(1,3-thiazol-5-yl)-8-(trifluoromethyl)quinazolin-4-yl]amino]benzamide
Show/Hide
|
C19H12F3N5OS
|
1
|
| 1 |
IC50 = 8 nM
|
|
|
|
CP0409957
|
N-(3-chloro-4-fluorophenyl)-8-methoxy-6-(1,3-thiazol-5-yl)quinazolin-4-amine
Show/Hide
|
C18H12ClFN4OS
|
1
|
| 1 |
IC50 = 9 nM
|
|
|
|
CP0451644
|
4-[[6-(1,3-thiazol-5-yl)quinazolin-4-yl]amino]cyclohexane-1-carboxamide
Show/Hide
|
C18H19N5OS
|
1
|
| 1 |
IC50 = 9 nM
|
|
|
|
CP0409985
|
N-(3-chloro-4-fluorophenyl)-8-methyl-6-(1,3-thiazol-5-yl)quinazolin-4-amine
Show/Hide
|
C18H12ClFN4S
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0481582
|
N-[(1S,2S)-2-methylcyclohexyl]-6-(1,3-thiazol-5-yl)quinazolin-4-amine
Show/Hide
|
C18H20N4S
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0482601
|
4-(oxan-4-ylamino)-6-(1,3-thiazol-5-yl)-1H-quinolin-2-one
Show/Hide
|
C17H17N3O2S
|
1
|
| 1 |
IC50 = 11 nM
|
|
|
|
CP0415308
|
N-[(1S,2R)-2-methylcyclohexyl]-6-(1,3-thiazol-5-yl)quinazolin-4-amine
Show/Hide
|
C18H20N4S
|
1
|
| 1 |
IC50 = 12 nM
|
|
|
|
CP0482651
|
N-ethyl-4-[[6-(1,3-thiazol-5-yl)quinazolin-4-yl]amino]cyclohexane-1-carboxamide
Show/Hide
|
C20H23N5OS
|
1
|
| 1 |
IC50 = 12 nM
|
|
|
|
CP0530439
|
N-cyclopentyl-6-(1,3-thiazol-5-yl)quinazolin-4-amine
Show/Hide
|
C16H16N4S
|
1
|
| 1 |
IC50 = 12 nM
|
|
|
|
CP0415310
|
N-[4-(1,3-oxazol-5-yl)phenyl]-6-(1,3-thiazol-5-yl)quinazolin-4-amine
Show/Hide
|
C20H13N5OS
|
1
|
| 1 |
IC50 = 13 nM
|
|
|
|
CP0489207
|
N-cyclohexyl-6-(1,3-thiazol-5-yl)quinazolin-4-amine
Show/Hide
|
C17H18N4S
|
1
|
| 1 |
IC50 = 13 nM
|
|
|
|
CP0241206
|
1-methyl-4-(oxan-4-ylamino)-6-(1,3-thiazol-5-yl)quinolin-2-one
Show/Hide
|
C18H19N3O2S
|
1
|
| 1 |
IC50 = 15 nM
|
|
|
|
CP0551548
|
N-(3-methylcyclohexyl)-6-(1,3-thiazol-5-yl)quinazolin-4-amine
Show/Hide
|
C18H20N4S
|
1
|
| 1 |
IC50 = 15 nM
|
|
|
|
CP0487036
|
N-(3-methylphenyl)-6-(1,3-thiazol-5-yl)quinazolin-4-amine
Show/Hide
|
C18H14N4S
|
1
|
| 1 |
IC50 = 17 nM
|
|
|
|
CP0469830
|
N-(3-chloro-4-fluorophenyl)-6-(1,3-thiazol-5-yl)quinolin-4-amine
Show/Hide
|
C18H11ClFN3S
|
1
|
| 1 |
IC50 = 19 nM
|
|
|
|
CP0498968
|
N-(3-chlorophenyl)-6-(1,3-thiazol-5-yl)quinazolin-4-amine
Show/Hide
|
C17H11ClN4S
|
1
|
| 1 |
IC50 = 19 nM
|
|
|
|
CP0481563
|
N-(4-methylphenyl)-6-(1,3-thiazol-5-yl)quinazolin-4-amine
Show/Hide
|
C18H14N4S
|
1
|
| 1 |
IC50 = 22 nM
|
|
|
|
CP0451648
|
N-pyridin-4-yl-6-(1,3-thiazol-5-yl)quinazolin-4-amine
Show/Hide
|
C16H11N5S
|
1
|
| 1 |
IC50 = 24 nM
|
|
|
|
CP0546317
|
4-[[6-(1,3-thiazol-5-yl)quinazolin-4-yl]amino]benzamide
Show/Hide
|
C18H13N5OS
|
1
|
| 1 |
IC50 = 24 nM
|
|
|
|
CP0415307
|
4-[[6-(1,3-thiazol-5-yl)quinazolin-4-yl]amino]cyclohexan-1-ol
Show/Hide
|
C17H18N4OS
|
1
|
| 1 |
IC50 = 25 nM
|
|
|
|
CP0428758
|
N-(4-chlorophenyl)-6-(1,3-thiazol-5-yl)quinazolin-4-amine
Show/Hide
|
C17H11ClN4S
|
1
|
| 1 |
IC50 = 26 nM
|
|
|
|
CP0482652
|
1-[4-[[6-(1,3-thiazol-5-yl)quinazolin-4-yl]amino]phenyl]pyrrolidin-2-one
Show/Hide
|
C21H17N5OS
|
1
|
| 1 |
IC50 = 26 nM
|
|
|
|
CP0546318
|
N-(4-imidazol-1-ylphenyl)-6-(1,3-thiazol-5-yl)quinazolin-4-amine
Show/Hide
|
C20H14N6S
|
1
|
| 1 |
IC50 = 26 nM
|
|
|
|
CP0451647
|
4-[[6-(1,3-thiazol-5-yl)quinazolin-4-yl]amino]benzenesulfonamide
Show/Hide
|
C17H13N5O2S2
|
1
|
| 1 |
IC50 = 27 nM
|
|
|
|
CP0469832
|
N-(3-fluorophenyl)-6-(1,3-thiazol-5-yl)quinazolin-4-amine
Show/Hide
|
C17H11FN4S
|
1
|
| 1 |
IC50 = 31 nM
|
|
|
|
CP0481583
|
N-(3-methylsulfonylphenyl)-6-(1,3-thiazol-5-yl)quinazolin-4-amine
Show/Hide
|
C18H14N4O2S2
|
1
|
| 1 |
IC50 = 31 nM
|
|
|
|
CP0489209
|
N-cyclobutyl-6-(1,3-thiazol-5-yl)quinazolin-4-amine
Show/Hide
|
C15H14N4S
|
1
|
| 1 |
IC50 = 31 nM
|
|
|
|
CP0566803
|
N-(4-fluorophenyl)-6-(1,3-thiazol-5-yl)quinazolin-4-amine
Show/Hide
|
C17H11FN4S
|
1
|
| 1 |
IC50 = 31 nM
|
|
|
|
CP0428757
|
N-(3-chloro-4-fluorophenyl)-6-(1,3-thiazol-5-yl)quinazolin-4-amine
Show/Hide
|
C17H10ClFN4S
|
1
|
| 1 |
IC50 = 32 nM
|
|
|
|
CP0428755
|
4-[[6-(1,3-thiazol-5-yl)quinazolin-4-yl]amino]piperidine-1-carboxamide
Show/Hide
|
C17H18N6OS
|
1
|
| 1 |
IC50 = 34 nM
|
|
|
|
CP0481580
|
(1R,3R)-3-[[6-(1,3-thiazol-5-yl)quinazolin-4-yl]amino]cyclohexane-1-carboxamide
Show/Hide
|
C18H19N5OS
|
1
|
| 1 |
IC50 = 37 nM
|
|
|
|
CP0547406
|
N-methyl-4-[[8-methyl-6-(1,3-thiazol-5-yl)-2-(trifluoromethyl)quinazolin-4-yl]amino]cyclohexane-1-carboxamide
Show/Hide
|
C21H22F3N5OS
|
1
|
| 1 |
IC50 = 37 nM
|
|
|
|
CP0451643
|
4-[[6-(1,3-thiazol-5-yl)quinazolin-4-yl]amino]cyclohexane-1-carboxylic acid
Show/Hide
|
C18H18N4O2S
|
1
|
| 1 |
IC50 = 40 nM
|
|
|
|
CP0389610
|
6-(1,3-thiazol-5-yl)-N-[3-(trifluoromethyl)phenyl]quinazolin-4-amine
Show/Hide
|
C18H11F3N4S
|
1
|
| 1 |
IC50 = 42 nM
|
|
|
|
CP0508019
|
N-(oxan-3-yl)-6-(1,3-thiazol-5-yl)quinazolin-4-amine
Show/Hide
|
C16H16N4OS
|
1
|
| 1 |
IC50 = 45 nM
|
|
|
|
CP0508021
|
N-(2-fluorophenyl)-6-(1,3-thiazol-5-yl)quinazolin-4-amine
Show/Hide
|
C17H11FN4S
|
1
|
| 1 |
IC50 = 45 nM
|
|
|
|
CP0469831
|
N-phenyl-6-(1,3-thiazol-5-yl)quinazolin-4-amine
Show/Hide
|
C17H12N4S
|
1
|
| 1 |
IC50 = 46 nM
|
|
|
|
CP0549241
|
N-[4-[[6-(1,3-thiazol-5-yl)quinazolin-4-yl]amino]phenyl]methanesulfonamide
Show/Hide
|
C18H15N5O2S2
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0508020
|
N-(oxan-4-yl)-6-(1,3-thiazol-5-yl)quinazolin-4-amine
Show/Hide
|
C16H16N4OS
|
1
|
| 1 |
IC50 = 51 nM
|
|
|
|
CP0451646
|
N-(2-chlorophenyl)-6-(1,3-thiazol-5-yl)quinazolin-4-amine
Show/Hide
|
C17H11ClN4S
|
1
|
| 1 |
IC50 = 58 nM
|
|
|
|
CP0428760
|
N-pyridin-3-yl-6-(1,3-thiazol-5-yl)quinazolin-4-amine
Show/Hide
|
C16H11N5S
|
1
|
| 1 |
IC50 = 59 nM
|
|
|
|
CP0508022
|
N-(2-methylphenyl)-6-(1,3-thiazol-5-yl)quinazolin-4-amine
Show/Hide
|
C18H14N4S
|
1
|
| 1 |
IC50 = 65 nM
|
|
|
|
CP0530441
|
N-tert-butyl-6-(1,3-thiazol-5-yl)quinazolin-4-amine
Show/Hide
|
C15H16N4S
|
1
|
| 1 |
IC50 = 66 nM
|
|
|
|
CP0397784
|
N-methyl-4-[[2-methyl-6-(1,3-thiazol-5-yl)-8-(trifluoromethyl)quinazolin-4-yl]amino]cyclohexane-1-carboxamide
Show/Hide
|
C21H22F3N5OS
|
1
|
| 1 |
IC50 = 72 nM
|
|
|
|
CP0489210
|
N-propan-2-yl-6-(1,3-thiazol-5-yl)quinazolin-4-amine
Show/Hide
|
C14H14N4S
|
1
|
| 1 |
IC50 = 75 nM
|
|
|
|
CP0478178
|
1-[4-[[6-(1,3-thiazol-5-yl)quinazolin-4-yl]amino]cyclohexyl]pyrrolidin-2-one
Show/Hide
|
C21H23N5OS
|
1
|
| 1 |
IC50 = 77 nM
|
|
|
|
CP0549996
|
N-(1,1-dioxothian-4-yl)-6-(1,3-thiazol-5-yl)quinazolin-4-amine
Show/Hide
|
C16H16N4O2S2
|
1
|
| 1 |
IC50 = 85 nM
|
|
|
|
CP0428756
|
N-(oxolan-3-yl)-6-(1,3-thiazol-5-yl)quinazolin-4-amine
Show/Hide
|
C15H14N4OS
|
1
|
| 1 |
IC50 = 86 nM
|
|
|
|
CP0546319
|
N-pyridin-2-yl-6-(1,3-thiazol-5-yl)quinazolin-4-amine
Show/Hide
|
C16H11N5S
|
1
|
| 1 |
IC50 = 97 nM
|
|
|
|
CP0481562
|
N-(4-methylsulfonylcyclohexyl)-6-(1,3-thiazol-5-yl)quinazolin-4-amine
Show/Hide
|
C18H20N4O2S2
|
1
|
| 1 |
IC50 = 135 nM
|
|
|
|
CP0555862
|
N-(3-chloro-4-fluorophenyl)-6-(1,3-thiazol-5-yl)-8-(trifluoromethyl)quinazolin-4-amine
Show/Hide
|
C18H9ClF4N4S
|
1
|
| 1 |
IC50 = 139 nM
|
|
|
|
CP0488087
|
N-cyclopropyl-6-(1,3-thiazol-5-yl)quinazolin-4-amine
Show/Hide
|
C14H12N4S
|
1
|
| 1 |
IC50 = 144 nM
|
|
|
|
CP0566855
|
N-ethyl-6-(1,3-thiazol-5-yl)quinazolin-4-amine
Show/Hide
|
C13H12N4S
|
1
|
| 1 |
IC50 = 145 nM
|
|
|
|
CP0414621
|
4-amino-1-methyl-6-(1,3-thiazol-5-yl)quinolin-2-one
Show/Hide
|
C13H11N3OS
|
1
|
| 1 |
IC50 = 163 nM
|
|
|
|
CP0489211
|
2-[[6-(1,3-thiazol-5-yl)quinazolin-4-yl]amino]ethanol
Show/Hide
|
C13H12N4OS
|
1
|
| 1 |
IC50 = 189 nM
|
|
|
|
CP0489208
|
4-(3-chloro-4-fluoroanilino)-6-(1,3-thiazol-5-yl)quinoline-3-carboxamide
Show/Hide
|
C19H12ClFN4OS
|
1
|
| 1 |
IC50 = 205 nM
|
|
|
|
CP0498967
|
N-piperidin-4-yl-6-(1,3-thiazol-5-yl)quinazolin-4-amine
Show/Hide
|
C16H17N5S
|
1
|
| 1 |
IC50 = 275 nM
|
|
|
|
CP0549240
|
N-piperidin-3-yl-6-(1,3-thiazol-5-yl)quinazolin-4-amine
Show/Hide
|
C16H17N5S
|
1
|
| 1 |
IC50 = 296 nM
|
|
|
|
CP0478179
|
N-(2-methoxyethyl)-6-(1,3-thiazol-5-yl)quinazolin-4-amine
Show/Hide
|
C14H14N4OS
|
1
|
| 1 |
IC50 = 298 nM
|
|
|
|
CP0548365
|
4-[[6-(1,3-thiazol-5-yl)quinazolin-4-yl]amino]cyclohexane-1-carboxylic acid
Show/Hide
|
C18H18N4O2S
|
1
|
| 1 |
IC50 = 459 nM
|
|
|
|
CP0547405
|
1-[4-[[6-(1,3-thiazol-5-yl)quinazolin-4-yl]amino]cyclohexyl]pyrrolidin-2-one
Show/Hide
|
C21H23N5OS
|
1
|
| 1 |
IC50 = 1110 nM
|
|
|
