Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)amino}phenyl)formamido]pentanedioic acid
    Show/Hide
 PubChem ID
CID: 126941
SID: 14760074
Canonical SMILES
CN(Cc1cnc2nc(N)nc(N)c2n1)c1ccc(cc1)C(=O)N[C@@H](CCC(O)=O)C(O)=O
    Show/Hide
Compound Formula C20H22N8O5
Compound Structure
Protein Name
 Protein Info 
Folate receptor alpha
Protein Classification
Membrane receptor
Uniprot ID
P15328
Gene Name
FOLR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000938 Chinese hamster RT16
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  3
1
IC50 = 114 nM
   TI
   LI
   LO
   TS
2
IC50 = 216 nM
   TI
   LI
   LO
   TS
3
IC50 = 461 nM
   TI
   LI
   LO
   TS