| Compound ID |
Compound Name |
Compound Formula |
|
CP0434285
|
2-(ethylamino)-6-[3-[4-(trifluoromethylsulfanyl)phenyl]propanoyl]-7,8-dihydro-5H-pyrido[4,3-d]pyrimidine-4-carboxamide
Show/Hide
|
C20H22F3N5O2S
|
2
|
| 1 |
EC50 = 1.6 nM
|
|
|
| 2 |
EC50 = 48 nM
|
|
|
|
CP0428836
|
2-ethyl-6-[3-[4-(trifluoromethoxy)phenyl]propanoyl]-7,8-dihydro-5H-pyrido[4,3-d]pyrimidine-4-carboxamide
Show/Hide
|
C20H21F3N4O3
|
2
|
| 1 |
EC50 = 2 nM
|
|
|
| 2 |
EC50 = 83 nM
|
|
|
|
CP0130477
|
2-(ethylamino)-6-[3-[4-(trifluoromethoxy)phenyl]propanoyl]-7,8-dihydro-5H-pyrido[4,3-d]pyrimidine-4-carboxamide
Show/Hide
|
C20H22F3N5O3
|
2
|
| 1 |
EC50 = 2.3 nM
|
|
|
| 2 |
EC50 = 75 nM
|
|
|
|
CP0146999
|
2-(ethylamino)-6-[3-(4-propan-2-ylphenyl)propanoyl]-7,8-dihydro-5H-pyrido[4,3-d]pyrimidine-4-carboxamide
Show/Hide
|
C22H29N5O2
|
2
|
| 1 |
EC50 = 2.5 nM
|
|
|
| 2 |
EC50 = 158 nM
|
|
|
|
CP0428730
|
6-[3-[4-(1,1-difluoroethyl)phenyl]propanoyl]-2-(ethylamino)-7,8-dihydro-5H-pyrido[4,3-d]pyrimidine-4-carboxamide
Show/Hide
|
C21H25F2N5O2
|
2
|
| 1 |
EC50 = 2.7 nM
|
|
|
| 2 |
EC50 = 146 nM
|
|
|
|
CP0428728
|
2-cyclopropyl-6-[3-[4-(trifluoromethoxy)phenyl]propanoyl]-7,8-dihydro-5H-pyrido[4,3-d]pyrimidine-4-carboxamide
Show/Hide
|
C21H21F3N4O3
|
2
|
| 1 |
EC50 = 2.8 nM
|
|
|
| 2 |
EC50 = 43 nM
|
|
|
|
CP0499267
|
2-ethoxy-6-[3-[4-(trifluoromethoxy)phenyl]propanoyl]-7,8-dihydro-5H-pyrido[4,3-d]pyrimidine-4-carboxamide
Show/Hide
|
C20H21F3N4O4
|
2
|
| 1 |
EC50 = 3.3 nM
|
|
|
| 2 |
EC50 = 112 nM
|
|
|
|
CP0434202
|
2-(ethylamino)-6-[3-[4-(2,2,2-trifluoroethyl)phenyl]propanoyl]-7,8-dihydro-5H-pyrido[4,3-d]pyrimidine-4-carboxamide
Show/Hide
|
C21H24F3N5O2
|
2
|
| 1 |
EC50 = 4.7 nM
|
|
|
| 2 |
EC50 = 154 nM
|
|
|
|
CP0428729
|
2-(ethylamino)-6-[3-(4-ethylphenyl)propanoyl]-7,8-dihydro-5H-pyrido[4,3-d]pyrimidine-4-carboxamide
Show/Hide
|
C21H27N5O2
|
2
|
| 1 |
EC50 = 9.2 nM
|
|
|
| 2 |
EC50 = 215 nM
|
|
|
|
CP0191568
|
N-(3-chloro-4-methylphenyl)-3-(2-chlorophenyl)-N,5-dimethyl-1,2-oxazole-4-carboxamide
Show/Hide
|
C19H16Cl2N2O2
|
2
|
| 1 |
EC50 = 24 nM
|
|
|
| 2 |
EC50 = 316 nM
|
|
|
|
CP0387036
|
6-[3-[6-(1,1-difluoroethyl)pyridin-3-yl]propanoyl]-2-(ethylamino)-7,8-dihydro-5H-pyrido[4,3-d]pyrimidine-4-carboxamide
Show/Hide
|
C20H24F2N6O2
|
2
|
| 1 |
EC50 = 43 nM
|
|
|
| 2 |
EC50 = 2990 nM
|
|
|
|
CP0392778
|
N-(4-chlorophenyl)-5-ethyl-N-methyl-3-phenyltriazole-4-carboxamide
Show/Hide
|
C18H17ClN4O
|
2
|
| 1 |
EC50 = 47 nM
|
|
|
| 2 |
EC50 = 1420 nM
|
|
|
|
CP0506990
|
2-(ethylamino)-6-[3-(4-methylphenyl)propanoyl]-7,8-dihydro-5H-pyrido[4,3-d]pyrimidine-4-carboxamide
Show/Hide
|
C20H25N5O2
|
2
|
| 1 |
EC50 = 78 nM
|
|
|
| 2 |
EC50 = 3780 nM
|
|
|
|
CP0460625
|
2-(ethylamino)-6-[3-(4-methoxyphenyl)propanoyl]-7,8-dihydro-5H-pyrido[4,3-d]pyrimidine-4-carboxamide
Show/Hide
|
C20H25N5O3
|
2
|
| 1 |
EC50 = 137 nM
|
|
|
| 2 |
EC50 = 2430 nM
|
|
|
|
CP0386163
|
2-(4-bromophenyl)-N-((7-methoxy-2-(thiophen-3-yl)quinolin-3-yl)methyl)ethanamine
Show/Hide
|
C23H21BrN2OS
|
2
|
| 1 |
EC50 = 154 nM
|
|
|
| 2 |
EC50 = 3220 nM
|
|
|
|
CP0191847
|
6alpha-ethyl-23(S)-methyl-cholic acid
Show/Hide
|
C27H46O5
|
2
|
| 1 |
EC50 = 166 nM
|
|
|
| 2 |
EC50 = 5540 nM
|
|
|
|
CP0460627
|
2-(ethylamino)-6-(3-phenylpropanoyl)-7,8-dihydro-5H-pyrido[4,3-d]pyrimidine-4-carboxamide
Show/Hide
|
C19H23N5O2
|
2
|
| 1 |
EC50 = 257 nM
|
|
|
| 2 |
EC50 = 8320 nM
|
|
|
