General Information of the Protein
| Protein ID |
PT04077
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| Protein Name |
Vasoactive intestinal polypeptide receptor 2
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| Secondarily Protein Name |
Helodermin-preferring VIP receptor
Pituitary adenylate cyclase-activating polypeptide type III receptor
VPAC2
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| Gene Name |
VIPR2
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| Secondarily Gene Name |
VIP2R
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| Sequence |
MRTLLPPALLTCWLLAPVNSIHPECRFHLEIQEEETKCAELLRSQTEKHKACSGVWDNITCWRPANVGETVTVPCPKVFSNFYSKAGNISKNCTSDGWSETFPDFVDACGYSDPEDESKITFYILVKAIYTLGYSVSLMSLATGSIILCLFRKLHCTRNYIHLNLFLSFILRAISVLVKDDVLYSSSGTLHCPDQPSSWVGCKLSLVFLQYCIMANFFWLLVEGLYLHTLLVAMLPPRRCFLAYLLIGWGLPTVCIGAWTAARLYLEDTGCWDTNDHSVPWWVIRIPILISIIVNFVLFISIIRILLQKLTSPDVGGNDQSQYKRLAKSTLLLIPLFGVHYMVFAVFPISISSKYQILFELCLGSFQGLVVAVLYCFLNSEVQCELKRKWRSRCPTPSASRDYRVCGSSFSRNGSEGALQFHRGSRAQSFLQTETSVI
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| Organism |
Homo sapiens, Human
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| Protein Classification |
Membrane receptor
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Family B G protein-coupled receptor
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Peptide receptor (family B GPCR)
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Vasoactive intestinal peptide receptor
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Vasoactive intestinal peptide receptor
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| Function |
This is a receptor for VIP as well as PACAP-38 and -27, the activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Can be coupled to phospholipase C.
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| Uniprot ID |
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| Ensembl ID | |||||
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| Subcellular Location |
Cell membrane
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Map of Molecular Bioactivity Related to the Protein
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Map of Molecular Bioactivity Related to the Protein Protein Cell Line Compound Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Protein
Cell Line ID: CL000011 , CHO
Cell Line ID: CL000026 , CHO-K1
Cell Line ID: CL000386 , Flp-In-CHO
Cell Line ID: CL000006 , HEK293
Clinical Information about the Protein
Target 1 ( Helodermin-preferring VIP receptor (VIPR2) )
| Target Type | Clinical trial Target | ||||
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