| Compound ID |
Compound Name |
Compound Formula |
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CP0039348
|
(2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide
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C12H16N6O4
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4
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| 1 |
EC50 = 2.512 nM
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|
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| 2 |
EC50 = 3.311 nM
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|
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| 3 |
EC50 = 4.786 nM
|
|
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| 4 |
EC50 = 12.59 nM
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CP0041258
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(CGS21680) 3-(4-{2-[6-Amino-9-(5-ethylcarbamoylmethyl-3,4-dihydroxy-tetrahydro-furan-2-yl)-9H-purin-2-ylamino]-ethyl}-phenyl)-propionic acid
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|
C23H29N7O6
|
1
|
| 1 |
EC50 = 12.59 nM
|
|
|
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CP0544796
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N-[4-[4-[[9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]purin-6-yl]amino]phenyl]butyl]benzamide
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|
C27H30N6O5
|
1
|
| 1 |
EC50 = 37.15 nM
|
|
|
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CP0394586
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(2S,3S,4R,5R)-5-[6-[6-[[4-[5-amino-4-benzoyl-3-[3-(trifluoromethyl)phenyl]thiophen-2-yl]benzoyl]amino]hexylamino]purin-9-yl]-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide
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|
C43H43F3N8O6S
|
1
|
| 1 |
EC50 = 56.23 nM
|
|
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CP0451309
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4-[[4-[[9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]purin-6-yl]amino]phenyl]methylcarbamoyl]benzenesulfonyl fluoride
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|
C24H23FN6O7S
|
1
|
| 1 |
EC50 = 67.61 nM
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|
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CP0451310
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1-[[4-[[9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]purin-6-yl]amino]phenyl]methyl]-3-(4-isothiocyanatophenyl)thiourea
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|
C25H24N8O4S2
|
1
|
| 1 |
EC50 = 67.61 nM
|
|
|
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CP0546140
|
[2-amino-5-[4-[1-[6-[[9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]purin-6-yl]amino]hexyl]triazol-4-yl]phenyl]-4-[3-(trifluoromethyl)phenyl]thiophen-3-yl]-phenylmethanone
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|
C42H40F3N9O5S
|
1
|
| 1 |
EC50 = 72.44 nM
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|
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CP0018686
|
(2S,3S,4R,5R)-3,4-Dihydroxy-5-[6-(3-iodo-benzylamino)-purin-9-yl]-tetrahydro-furan-2-carboxylic acid methylamide
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|
C18H19IN6O4
|
1
|
| 1 |
EC50 = 79.43 nM
|
|
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CP0880308
|
2-Amino-N6-phenethyladenosine-5'-N-methylcarboxamide
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|
C19H23N7O4
|
1
|
| 1 |
EC50 = 79.43 nM
|
|
|
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CP0394595
|
4-[5-amino-4-benzoyl-3-[3-(trifluoromethyl)phenyl]thiophen-2-yl]-N-[6-[[2-chloro-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]purin-6-yl]amino]hexyl]benzamide
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|
C41H39ClF3N7O6S
|
1
|
| 1 |
EC50 = 144.54 nM
|
|
|
|
CP0408494
|
3-[5-amino-4-benzoyl-3-[3-(trifluoromethyl)phenyl]thiophen-2-yl]-N-[6-[[9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]purin-6-yl]amino]hexyl]benzamide
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|
C41H40F3N7O6S
|
1
|
| 1 |
EC50 = 147.91 nM
|
|
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CP0856534
|
2-Amino-N6-(3-iodobenzyl)adenosine-5'-N-methylcarboxamide
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|
C18H20IN7O4
|
1
|
| 1 |
EC50 = 251.19 nM
|
|
|
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CP0549807
|
4-[5-amino-4-benzoyl-3-[3-(trifluoromethyl)phenyl]thiophen-2-yl]-N-[3-[4-[[9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]purin-6-yl]amino]phenyl]propyl]benzamide
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|
C44H38F3N7O6S
|
1
|
| 1 |
EC50 = 288.4 nM
|
|
|
|
CP0389165
|
4-(5-amino-4-benzoylthiophen-2-yl)-N-[6-[[9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]purin-6-yl]amino]hexyl]benzamide
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|
C34H37N7O6S
|
1
|
| 1 |
EC50 = 354.81 nM
|
|
|
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CP0546135
|
4-[5-amino-4-benzoyl-3-[3-(trifluoromethyl)phenyl]thiophen-2-yl]-N-[2-[4-[2-[[9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]purin-6-yl]amino]ethyl]phenyl]ethyl]benzamide
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|
C45H40F3N7O6S
|
1
|
| 1 |
EC50 = 363.08 nM
|
|
|
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CP0394589
|
4-[5-amino-4-benzoyl-3-[3-(trifluoromethyl)phenyl]thiophen-2-yl]-N-[6-[[9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]purin-6-yl]amino]hexyl]benzamide
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|
C41H40F3N7O6S
|
2
|
| 1 |
EC50 = 389.05 nM
|
|
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| 2 |
EC50 = 2290.87 nM
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CP0884485
|
2-Amino-N6-(3-chlorobenzyl)adenosine-5'-N-methylcarboxamide
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|
C18H20ClN7O4
|
1
|
| 1 |
EC50 = 398.11 nM
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|
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CP0389138
|
3-(4-benzoylthiophen-2-yl)-N-[6-[[9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]purin-6-yl]amino]hexyl]benzamide
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|
C34H36N6O6S
|
1
|
| 1 |
EC50 = 436.52 nM
|
|
|
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CP0880309
|
2-Ethylamino-N6-cyclopentyladenosine-5'-N-methylcarboxamide
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|
C18H27N7O4
|
1
|
| 1 |
EC50 = 501.19 nM
|
|
|
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CP0389136
|
N-[6-[[9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]purin-6-yl]amino]hexyl]-4-[3-[3-(trifluoromethyl)phenyl]thiophen-2-yl]benzamide
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|
C34H35F3N6O5S
|
1
|
| 1 |
EC50 = 645.65 nM
|
|
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CP0444859
|
(2R,3S,4R,5R)-2-(hydroxymethyl)-5-[6-[4-(isothiocyanatomethyl)anilino]purin-9-yl]oxolane-3,4-diol
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|
C18H18N6O4S
|
1
|
| 1 |
EC50 = 645.65 nM
|
|
|
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CP0546136
|
4-[5-amino-4-benzoyl-3-[3-(trifluoromethyl)phenyl]thiophen-2-yl]-N-[4-[4-[[9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]purin-6-yl]amino]phenyl]but-3-ynyl]benzamide
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|
C45H36F3N7O6S
|
1
|
| 1 |
EC50 = 741.31 nM
|
|
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CP0417389
|
4-[5-amino-4-benzoyl-3-[3-(trifluoromethyl)phenyl]thiophen-2-yl]-N-[6-[[2-amino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]purin-6-yl]amino]hexyl]benzamide
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|
C41H41F3N8O6S
|
1
|
| 1 |
EC50 = 758.58 nM
|
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CP0856535
|
2-Amino-N6-cyclohexyladenosine-5'-N-methylcarboxamide
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|
C17H25N7O4
|
1
|
| 1 |
EC50 = 794.33 nM
|
|
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CP0884489
|
2-Amino-N6-(2,2-diphenylethyl)adenosine-5'-N-methylcarboxamide
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|
C25H27N7O4
|
1
|
| 1 |
EC50 = 794.33 nM
|
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CP0394587
|
3-(5-aminothiophen-2-yl)-N-[6-[[9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]purin-6-yl]amino]hexyl]benzamide
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|
C27H33N7O5S
|
1
|
| 1 |
EC50 = 1071.52 nM
|
|
|
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CP0882253
|
2-Amino-N6-cyclopentyladenosine-5'-N-methylcarboxamide
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|
C16H23N7O4
|
1
|
| 1 |
EC50 = 1258.93 nM
|
|
|
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CP0389164
|
N-[6-[[9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]purin-6-yl]amino]hexyl]-3-thiophen-2-ylbenzamide
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|
C27H32N6O5S
|
1
|
| 1 |
EC50 = 1318.26 nM
|
|
|
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CP0478404
|
4-[5-acetamido-4-benzoyl-3-[3-(trifluoromethyl)phenyl]thiophen-2-yl]-N-[6-[[9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]purin-6-yl]amino]hexyl]benzamide
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|
C43H42F3N7O7S
|
1
|
| 1 |
EC50 = 2344.23 nM
|
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CP0884491
|
2-Amino-N6-cyclobutyladenosine-5'-N-methylcarboxamide
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|
C15H21N7O4
|
1
|
| 1 |
EC50 = 2511.89 nM
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CP0389166
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4-[5-amino-3-[3-(trifluoromethyl)phenyl]thiophen-2-yl]-N-[6-[[9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]purin-6-yl]amino]hexyl]benzamide
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|
C34H36F3N7O5S
|
1
|
| 1 |
EC50 = 2691.53 nM
|
|
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CP0394590
|
4-[4-benzoyl-3-[3-(trifluoromethyl)phenyl]thiophen-2-yl]-N-[6-[[9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]purin-6-yl]amino]hexyl]benzamide
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|
C41H39F3N6O6S
|
1
|
| 1 |
EC50 = 2884.03 nM
|
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CP0911591
|
2-Amino-N6-benzyladenosine-5'-N-methylcarboxamide
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|
C18H21N7O4
|
1
|
| 1 |
EC50 = 3162.28 nM
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CP0394585
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4-[5-amino-4-benzoyl-3-[3-(trifluoromethyl)phenyl]thiophen-2-yl]-N-[5-[[9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]purin-6-yl]amino]pentyl]benzamide
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|
C40H38F3N7O6S
|
1
|
| 1 |
EC50 = 3630.78 nM
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CP0851043
|
2-Methylamino-N6-cyclopentyladenosine-5'-N-methylcarboxamide
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|
C17H25N7O4
|
1
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| 1 |
EC50 = 3981.07 nM
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CP0417388
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4-[5-amino-4-benzoyl-3-[3-(trifluoromethyl)phenyl]thiophen-2-yl]-N-[7-[[9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]purin-6-yl]amino]heptyl]benzamide
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|
C42H42F3N7O6S
|
1
|
| 1 |
EC50 = 4897.79 nM
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CP0856536
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2-Dimethylamino-N6-cyclopentyladenosine-5'-N-methylcarboxamide
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C18H27N7O4
|
1
|
| 1 |
EC50 = 5011.87 nM
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CP0851044
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2-Amino-N6-methyladenosine-5'-N-methylcarboxamide
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|
C12H17N7O4
|
1
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| 1 |
EC50 > 10000 nM
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CP0856532
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2-Diethylamino-N6-cyclopentyladenosine-5'-N-methylcarboxamide
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|
C20H31N7O4
|
1
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| 1 |
EC50 > 10000 nM
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CP0856533
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2-Amino-N6-ethyladenosine-5'-N-methylcarboxamide
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|
C13H19N7O4
|
1
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| 1 |
EC50 > 10000 nM
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CP0880307
|
2-Amino-N6-butyladenosine-5'-N-methylcarboxamide
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|
C15H23N7O4
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1
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| 1 |
EC50 > 10000 nM
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CP0882232
|
2-Amino-N6-propyladenosine-5'-N-methylcarboxamide
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|
C14H21N7O4
|
1
|
| 1 |
EC50 > 10000 nM
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CP0398724
|
tert-butyl N-[12-oxo-12-[3-[2-(2-oxo-1,3-dihydroindol-4-yl)ethyl-propylamino]propylamino]dodecyl]carbamate
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|
C33H56N4O4
|
1
|
| 1 |
IC50 > 100000 nM
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