Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(2S)-2-{2-[(2R)-2-[(2S)-2-amino-3-(4-hydroxyphenyl)propanamido]propanamido]-N-methylacetamido}-N-(2-hydroxyethyl)-3-phenylpropanamide
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 PubChem ID
CID: 5462471
SID: 14933805
Canonical SMILES
C[C@@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)NCC(=O)N(C)[C@@H](Cc1ccccc1)C(=O)NCCO
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Compound Formula C26H35N5O6
Compound Structure
Protein Name
 Protein Info 
Mu-type opioid receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
>
Short peptide receptor (family A GPCR)
>
Opioid receptor
Uniprot ID
P33535
Gene Name
OPRM1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000049 C6
 Cell Line Info 
Rattus norvegicus (Rat)  1
1
EC50 = 146 nM
   TI
   LI
   LO
   TS
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  4
1
EC50 = 8.06 nM
   TI
   LI
   LO
   TS
2
EC50 = 81 nM
   TI
   LI
   LO
   TS
3
IC50 = 3 nM
   TI
   LI
   LO
   TS
4
Ki = 2.3 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 0.26 nM
   TI
   LI
   LO
   TS
CL000661 HN9.10e
 Cell Line Info 
Mus musculus (Mouse)  2
1
IC50 = 36.31 nM
   TI
   LI
   LO
   TS
2
Ki = 16 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 3.5 nM
2 Ki = 0.85 nM
3 Ki = 0.87 nM
4 Ki = 1.64 nM
5 Ki = 4 nM