Brief Information of the Compound and Protein
Compound Name
2-[4-({6-[6-Amino-1,3-dioxo-1H-benzo[de]isoquinolin-2(3H)-yl]hexanoyl}amino)piperidino]ethyl 4-Amino-5-chloro-2-methoxybenzoate
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PubChem ID
CID: 44582815
Canonical SMILES
COc1cc(N)c(Cl)cc1C(=O)OCCN1CCC(NC(=O)CCCCN2C(=O)c3cccc4c(N)ccc(c34)C2=O)CC1
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Compound Formula C32H36ClN5O6
Compound Structure
Protein Name
5-hydroxytryptamine receptor 4
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
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Monoamine receptor
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Serotonin receptor
Uniprot ID
Q13639
Gene Name
HTR4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000049 C6 Rattus norvegicus (Rat)  2
1
EC50 = 4 nM
   TI
   LI
   LO
   TS
2
Ki = 111 nM
   TI
   LI
   LO
   TS