General Information of the Compound
Compound ID
CP0486722
Compound Name
CHEMBL4741702
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Formula
C24H36ClN3O2
Molecular Weight
434.024
Canonical SMILES
C[C@H]1CN(CC[C@H]2CC[C@@H](CC2)NC(=O)N2CCOCC2)CCc2ccc(Cl)cc12
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InChI
InChI=1S/C24H36ClN3O2/c1-18-17-27(11-9-20-4-5-21(25)16-23(18)20)10-8-19-2-6-22(7-3-19)26-24(29)28-12-14-30-15-13-28/h4-5,16,18-19,22H,2-3,6-15,17H2,1H3,(H,26,29)/t18-,19-,22-/m0/s1
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InChIKey
UNEYERITNKRLJR-IPJJNNNSSA-N
Physicochemical Property
logP
4.2923
Rotatable Bonds
4
Heavy Atom Count
30
Polar Areas
44.81
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
3
Complexity
30

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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ChEMBL ID
CHEMBL4741702
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01005, D(2) dopamine receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 2.9 nM
   TI
   LI
   LO
   TS
Protein ID: PT00943, D(3) dopamine receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 1.8 nM
   TI
   LI
   LO
   TS