General Information of the Compound
Compound ID
CP0389485
Compound Name
ethyl (4aR,10bR)-4-propyl-2,3,4a,5,6,10b-hexahydrobenzo[h][1,4]benzoxazine-9-carboxylate
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Structure
Formula
C18H25NO3
Molecular Weight
303.402
Canonical SMILES
CCCN1CCO[C@H]2[C@H]1CCc1ccc(cc21)C(=O)OCC
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InChI
InChI=1S/C18H25NO3/c1-3-9-19-10-11-22-17-15-12-14(18(20)21-4-2)6-5-13(15)7-8-16(17)19/h5-6,12,16-17H,3-4,7-11H2,1-2H3/t16-,17-/m1/s1
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InChIKey
DTNBLXRAVILHMO-IAGOWNOFSA-N
Physicochemical Property
logP
2.9614
Rotatable Bonds
4
Heavy Atom Count
22
Polar Areas
38.77
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
4
Complexity
22

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 15389749
ChEMBL ID
CHEMBL485018
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00943, D(3) dopamine receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 2630.27 nM
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